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What are the treatments for Human T-cell leukemia virus type 1 ? | No cure or treatment exists for human T-cell leukemia virus, type 1 (HTLV-1). Management is focused on early detection and preventing the spread of HTLV-1 to others. Screening blood doners, promoting safe sex and discouraging needle sharing can decrease the number of new infections. Mother-to-child transmission can be ... | 0 |
Is the glutathione-related detoxification system increased in human breast cancer in correlation with clinical and histopathological features? | The breast tumours improved their redox status and detoxification capacities depending on various parameters of significance for cell proliferation and aggressiveness, which supports the involvement of the glutathione pathway in malignant cell resistance to oxidative stress and apoptosis. | 1 |
What are the genetic changes related to adermatoglyphia ? | Adermatoglyphia is caused by mutations in the SMARCAD1 gene. This gene provides information for making two versions of the SMARCAD1 protein: a full-length version that is active (expressed) in multiple tissues and a shorter version that is expressed only in the skin. Studies suggest that the full-length SMARCAD1 protei... | 2 |
What is (are) Psoriasis ? | Psoriasis is a chronic skin disease. Chronic means that it lasts a long time, often a lifetime. Psoriasis affects more than 5 million adults in the United States. It appears about equally in males and females. Psoriasis occurs when the skin cells grow too quickly. The body does not shed these excess cells and they buil... | 3 |
Is hilar location an independent prognostic factor for recurrence in T1 renal cell carcinoma after nephrectomy? | Hilar tumors show a higher recurrence rate than nonhilar counterparts in T1 RCC. In T1a hilar tumors, PN demonstrated poorer RFS than RN. Potential intrinsic renal anatomical or lymphovascular structural differences as well as differences in cancer characteristics need further investigations. | 4 |
What are the symptoms of Microcephaly deafness syndrome ? | The Human Phenotype Ontology provides the following list of signs and symptoms for Microcephaly deafness syndrome. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these me... | 5 |
How many people are affected by X-linked spondyloepiphyseal dysplasia tarda ? | The prevalence of X-linked spondyloepiphyseal dysplasia tarda is estimated to be 1 in 150,000 to 200,000 people worldwide. | 6 |
Does bevacizumab modulate epithelial-to-mesenchymal transition in the retinal pigment epithelial cells via connective tissue growth factor up-regulation? | Bevacizumab exerts pro-fibrotic effects on human RPE cells at clinical doses by up-regulation of CTGF expression via an Fc-FcR interaction. This effect of bevacizumab may be one of the underlying mechanisms involved in age-related macular degeneration therapy or intravitreal bevacizumab-associated complications. | 7 |
Does anti-prokineticin1 ( PROK1 ) monoclonal antibody suppress angiogenesis and tumor growth in colorectal cancer? | The in vitro and vivo experimental system indicated that the anti-PROK1mAb could suppress angiogenesis and tumor growth in the CRC strains. | 8 |
Is etomidate associated with mortality and adrenal insufficiency in sepsis : a meta-analysis*? | Administration of etomidate for rapid sequence intubation is associated with higher rates of adrenal insufficiency and mortality in patients with sepsis. | 9 |
Does geographical location and age affect the incidence of parasitic infestations in school children? | One of the greatest challenges for healthcare professionals is the prevention and treatment of protozoal and helminthic parasitic infections. From our study we conclude that the prevalence of different pathogenic species of amoeba such as Entamoeba histolytica (4.2 vs. 0%) and G. lamblia (17.9 vs. 14%), (P value was eq... | 10 |
Does nADPH oxidase 1 play a key role in diabetes mellitus-accelerated atherosclerosis? | These studies identify a major pathological role for Nox1 and suggest that Nox1-dependent oxidative stress is a promising target for diabetic vasculopathies, including atherosclerosis. | 11 |
Does the CDC Injury Center 's response to the growing public health problem of fall among older adults? | Falls in older adults will continue to rise substantially and become a significant cost to our health care system if we do not begin to focus on prevention in the clinical setting. | 12 |
What are the symptoms of Familial hypertrophic cardiomyopathy ? | The Human Phenotype Ontology provides the following list of signs and symptoms for Familial hypertrophic cardiomyopathy. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for th... | 13 |
Does hyperglycemia increase the risk of death in extremely preterm baboons? | HG is common in preterm baboons and is not associated with short-term morbidity. Severe HG occurring in the first week of life is associated with early death in preterm baboons. | 14 |
Do different gonadotropin and leuprorelin ovulation induction regimens markedly affect follicular fluid hormone levels and folliculogenesis? | Long GnRH-a regimens improved follicle yield and the endocrine milieu in spite of comparable exogenous gonadotropin dose and lower serum FSH and thus appear to be preferable in assisted reproduction. Reduced folliculogenesis found in flare-up GnRH-a regimens could be mediated by the atretic effects of high intraovarian... | 15 |
What are the treatments for Tay-Sachs disease ? | Although several attempts have been made at purified enzyme replacement therapy for children with Tay-Sachs disease, none has been successful. Cellular infusions and even bone marrow transplantation have been attempted with no evidence of benefit. Because no specific treatment is available for Tay-Sachs disease, treatm... | 16 |
Does anxiety during early pregnancy predict postpartum weight retention in obese mothers? | PPWR in obese mothers is associated with psychological discomfort during early pregnancy. Besides the importance of adequate prenatal weight management, focused psychological support should be an important cue to action in obese women, to prevent maternal obesity on the long run. | 17 |
Does butein provide neuroprotective and anti-neuroinflammatory effects through Nrf2/ARE-dependent haem oxygenase 1 expression by activating the PI3K/Akt pathway? | Our results indicate that butein effectively prevents glutamate-induced oxidative damage and LPS-induced activation and that the induction of HO1 by butein through the PI3K/Akt pathway and Nrf2 activation appears to play a pivotal role in its effects on neuronal cells. Our results provide evidence for the neuroprotecti... | 18 |
Is autosomal recessive congenital cataract in consanguineous Pakistani families associated with mutations in GALK1? | Here, we report pathogenic mutations in GALK1 that are responsible for autosomal recessive congenital cataracts in consanguineous Pakistani families. | 19 |
Do you have information about Ultrasound | Summary : Ultrasound is a type of imaging. It uses high-frequency sound waves to look at organs and structures inside the body. Health care professionals use it to view the heart, blood vessels, kidneys, liver, and other organs. During pregnancy, doctors use ultrasound to view the fetus. Unlike x-rays, ultrasound does ... | 20 |
What causes Simple Kidney Cysts ? | The cause of simple kidney cysts is not fully understood. Obstruction of tubulestiny structures within the kidneys that collect urineor deficiency of blood supply to the kidneys may play a role. Diverticulasacs that form on the tubulesmay detach and become simple kidney cysts. The role of genetic factors in the develop... | 21 |
Does surgical stress induce brain-derived neurotrophic factor reduction and postoperative cognitive dysfunction via glucocorticoid receptor phosphorylation in aged mice? | These results presented a mechanism that surgical stress-induced GR phosphorylation contributes to POCD in aged individuals. Inhibition of GR activation and phosphorylation might be a potential treatment target of POCD. | 22 |
Is quality of life more impaired in patients seeking medical care for food allergy? | Patients who seek medical care for their FA have a more impaired HRQL and perceive their FA as more severe. Food avoidance and issues related to the EI of FA are key areas of intervention aimed at improving HRQL in patients with FA. | 23 |
Are patient identification errors common in a simulated setting? | Wide variation exists among health care workers verifying patient identity before performing everyday tasks. Education, process changes, and technology are needed to improve the frequency and accuracy of patient identification. | 24 |
Is hepatitis C infection very rarely treated among hemodialysis patients? | HD patients with hepatitis C infection very rarely receive antiviral therapy. Increased intervention might prolong survival for some patients and in particular might improve the prospects for those awaiting renal transplantation. | 25 |
What is (are) Rickets ? | Rickets is a condition that causes children to have soft, weak bones. It usually occurs when children do not get enough vitamin D, which helps growing bones absorb important nutrients. Vitamin D comes from sunlight and food. Skin produces vitamin D in response to the sun's rays. Some foods also contain vitamin D, inclu... | 26 |
Does dasatinib induce autophagic cell death in human ovarian cancer? | Dasatinib induces autophagic cell death in ovarian cancer that partially depends on beclin 1, AKT, and Bcl-2. These results may have implications for clinical use of dasatinib. | 27 |
What are the treatments for Cornelia de Lange syndrome ? | Because Cornelia de Lange syndrome (CdLS) affects many different systems of the body, medical management is often provided by a team of doctors and other healthcare professionals. Treatment for this condition varies based on the signs and symptoms present in each person. For example, many people affected by CdLS have p... | 28 |
What are the genetic changes related to familial erythrocytosis ? | Familial erythrocytosis can result from mutations in the EPOR, VHL, EGLN1, or EPAS1 gene. Researchers define four types of familial erythrocytosis, ECYT1 through ECYT4, based on which of these genes is altered. The EPOR gene provides instructions for making a protein known as the erythropoietin receptor, which is foun... | 29 |
What is (are) Self-harm ? | Self-harm refers to a person's harming their own body on purpose. About 1 in 100 people hurts himself or herself in this way. More females hurt themselves than males. A person who self-harms usually does not mean to kill himself or herself. But they are at higher risk of attempting suicide if they do not get help. S... | 30 |
What are the genetic changes related to frontonasal dysplasia ? | Mutations in the ALX3 gene cause frontonasal dysplasia type 1, ALX4 gene mutations cause type 2, and ALX1 gene mutations cause type 3. These genes provide instructions for making proteins that are necessary for normal development, particularly of the head and face, before birth. The proteins produced from the ALX3, ALX... | 31 |
What are the symptoms of Cockayne syndrome type III ? | The Human Phenotype Ontology provides the following list of signs and symptoms for Cockayne syndrome type III. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these medica... | 32 |
Is sickle cell disease inherited ? | This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition. | 33 |
Does truncation mutation in HRG4 ( UNC119 ) lead to mitochondrial ANT-1-mediated photoreceptor synaptic and retinal degeneration by apoptosis? | The results support a novel mechanism of retinal degeneration in which preapoptotic degeneration starts in the photoreceptor synapse because of a deficiency in ANT-1 and spreads to the secondary neuron transsynaptically, followed by apoptosis and degeneration in the cell body of the photoreceptor. | 34 |
Is intraoperative blood loss a predictor of prognosis for pancreatic cancer? | Minimizing IBL is very important; however, the present study found that positive lymph node metastasis and R-status were stronger independent prognostic factors for pancreatic cancer. | 35 |
Do tuberculosis risk-associated single nucleotide polymorphisms show association with leprosy in Chinese population? | Although leprosy and TB have a number of similar characteristics, no shared susceptibility loci were found in the Chinese Han population. Thus, this study demonstrated that the genetic basis of the pathogenesis of the two diseases may vary greatly. | 36 |
Do serum cholesterol and statin use predict virological response to peginterferon and ribavirin therapy? | Baseline elevated LDL levels or low HDL levels and preemptive statin usage were associated with higher SVR rates. Prospective studies may be considered to explore the biological impact of these factors on HCV RNA replication and treatment response. | 37 |
Does functional interaction between Wnt3 and Frizzled-7 lead to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells? | These findings demonstrate a functional interaction between Wnt3 and FZD7 leading to activation of the Wnt/beta-catenin signaling pathway in HCC cells and may play a role during hepatocarcinogenesis. | 38 |
Is verapamil-sustained release-based treatment strategy equivalent to atenolol-based treatment strategy at reducing cardiovascular events in patients with prior myocardial infarction : an INternational VErapamil SR-Trandolapril ( INVEST ) substudy? | In hypertensive patients with prior MI, a verapamil-SR-based strategy was equivalent to a beta-blocker-based strategy for blood pressure control and prevention of cardiovascular events, with greater subjective feeling of well-being and a trend toward lower incidence of angina pectoris and stroke in the verapamil-SR-bas... | 39 |
Is transcranial Doppler-directed Dextran-40 therapy a cost-effective method of preventing carotid thrombosis after carotid endarterectomy? | postoperative TCD monitoring is a clinically effective and also cost-effective method of reducing the stroke rate associated with CEA. For units performing more than 50 CEAs per year who experience occasional postoperative carotid thrombosis, its introduction should be considered. | 40 |
Does communication of prenatal screening and diagnosis result to primary-care health professionals? | The frequent absence of means of effective communication between primary and secondary care about diagnosed abnormalities, and health professionals' uncertainties about their role has implications for the quality of care given to women who receive positive results after prenatal screening or diagnosis. There is a need ... | 41 |
What is (are) Diabetes and Pregnancy ? | Diabetes is a disease in which your blood glucose, or blood sugar, levels are too high. When you are pregnant, high blood sugar levels are not good for your baby. About seven out of every 100 pregnant women in the United States get gestational diabetes. Gestational diabetes is diabetes that happens for the first tim... | 42 |
Is Congenital myasthenic syndrome inherited ? | Almost all types of CMS are inherited in an autosomal recessive manner. In order to have the autosomal recessive form of CMS, both parents of an affected individual must be carriers of the disease causing mutation. If a person has CMS, but their partner is not a carrier of a CMS mutation, then their children will be ca... | 43 |
What is (are) Duane-radial ray syndrome ? | Duane-radial ray syndrome is a disorder that affects the eyes and causes abnormalities of bones in the arms and hands. This condition is characterized by a particular problem with eye movement called Duane anomaly (also known as Duane syndrome). This abnormality results from the improper development of certain nerves t... | 44 |
Is increased preference of surface ablation over laser in situ keratomileusis between 2008-2011 correlated to risk of ecatasia? | Our results indicate that with time, surface ablation tended to be performed more often than LASIK for the correction of myopia in our cohort. Increased awareness of risk factors and preoperative risk assessment tools, such as the ERFSS, have shifted the current practice of refractive surgery from LASIK towards surface... | 45 |
What are the symptoms of Osteopetrosis autosomal dominant type 2 ? | The Human Phenotype Ontology provides the following list of signs and symptoms for Osteopetrosis autosomal dominant type 2. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for... | 46 |
Do inhibition or knock out of inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury? | Taken together, our results clearly demonstrate that iNOS plays an important role in the lung injury induced by bleomycin in the mice. | 47 |
Do the incidence and complications of methicillin-resistant Staphylococcus aureus in a community Level I trauma center? | MRSA infections affect a minority of our trauma patients yet prolong length of stay. Admission MRSA screening of trauma patients does not sufficiently identify patients at risk for infectious complications and should not be practiced. | 48 |
What are the treatments for tetrasomy 18p ? | These resources address the diagnosis or management of tetrasomy 18p: - Chromosome 18 Clinical Research Center, University of Texas Health Science Center at San Antonio - Genetic Testing Registry: Chromosome 18, tetrasomy 18p These resources from MedlinePlus offer information about the diagnosis and management of v... | 49 |
What are the symptoms of Medullary Sponge Kidney ? | Many people with medullary sponge kidney have no symptoms. The first sign that a person has medullary sponge kidney is usually a UTI or a kidney stone. UTIs and kidney stones share many of the same signs and symptoms:
- burning or painful urination - pain in the back, lower abdomen, or groin - cloudy... | 50 |
What is (are) Crouzon syndrome ? | Crouzon syndrome is a genetic disorder characterized by the premature fusion of certain skull bones (craniosynostosis). This early fusion prevents the skull from growing normally and affects the shape of the head and face. Many features of Crouzon syndrome result from the premature fusion of the skull bones. Abnormal ... | 51 |
What is (are) Hemolytic uremic syndrome, atypical, childhood ? | Hemolytic uremic syndrome, atypical, childhood is a disease that causes abnormal blood clots to form in small blood vessels in the kidneys. These clots can cause serious medical problems if they restrict or block blood flow, including hemolytic anemia, thrombocytopenia, and kidney failure. It is often caused by a combi... | 52 |
Is the classic form of granular corneal dystrophy associated with R555W mutation in the BIGH3 gene rare in Japanese patients? | These results, together with our previous findings, show that the classic form of granular corneal dystrophy associated with the R555W mutation is rare in Japanese patients, whereas granular corneal dystrophy accompanied by amyloid deposits and associated with the R124H mutation, Avellino corneal dystrophy, is more com... | 53 |
What are the symptoms of Frank Ter Haar syndrome ? | The Human Phenotype Ontology provides the following list of signs and symptoms for Frank Ter Haar syndrome. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these medical t... | 54 |
What is (are) Twin twin transfusion syndrome ? | Twin-to-twin transfusion syndrome is a rare condition that occurs when blood moves from one identical twin (the donor twin) to the other (the recipient twin) while in the womb. The donor twin may be born smaller, with paleness, anemia, and dehydration. The recipient twin may be born larger, with redness, too much blood... | 55 |
What is (are) Pachydermoperiostosis ? | Pachydermoperiostosis is a rare disorder characterized by clubbing of the fingers and toes; thickening of the skin of the face (pachyderma); excessive sweating (hyperhidrosis); and new bone formation associated with joint pain. Other features may include congenital heart disease and delayed closure of fontanelles. This... | 56 |
Is neutrophil gelatinase-associated lipocalin a sensitive biomarker for the early diagnosis of acute rejection after living-donor kidney transplantation? | Urine NGAL level was found to be the most sensitive biomarker of acute kidney allograft dysfunction after living-donor kidney transplantation. | 57 |
Is hDL redox activity increased in HIV-infected men in association with macrophage activation and non-calcified coronary atherosclerotic plaque? | These data demonstrate increased HRA among HIV-infected subjects versus matched non-HIV subjects with comparable HDL levels. In HIV-infected subjects, HRA relates to macrophage activation and to non-calcified coronary atherosclerotic plaque, which may be rupture-prone. Further studies are needed in HIV-infected patient... | 58 |
Does comprehensive transcriptional profiling of NaCl-stressed Arabidopsis roots reveal novel classes of responsive genes? | Microarray profiling of NaCl-treated Arabidopsis roots revealed dynamic changes in transcript abundance for at least 20% of the genome, including hundreds of transcription factors, kinases/phosphatases, hormone-related genes, and effectors of homeostasis, all of which highlight the complexity of this stress response. O... | 59 |
What is (are) Childhood Central Nervous System Germ Cell Tumors ? | Key Points
- Childhood central nervous system (CNS) germ cell tumors form from germ cells. - There are different types of childhood CNS germ cell tumors. - Germinomas - Nongerminomas - The cause of most childhood CNS germ cell tumors is not known. - Signs and symptoms of c... | 60 |
Does intracytoplasmic sperm injection increase embryo fragmentation without affecting clinical outcome? | These data suggest that ICSI, irrespective of semen parameters, may increase embryo fragmentation and produce fewer nonfragmented grade I embryos while maintaining implantation and pregnancy rates similar to conventional IVF. | 61 |
What is (are) Mowat-Wilson syndrome ? | Mowat-Wilson syndrome (MWS) is a rare genetic disorder that affects many systems of the body. The main features include moderate to severe intellectual disability, distinctive facial features, and epilepsy. Other features may include Hirschsprung disease; heart (cardiac) defects; kidney (renal) abnormalities; genital a... | 62 |
Is elevated immune monitoring as measured by increased adenosine triphosphate production in activated lymphocytes associated with accelerated development of cardiac allograft vasculopathy after cardiac transplantation? | Elevated peak IM, as measured by increased ATP production, in activated lymphocytes is associated with decreased freedom from angiographic CAV. | 63 |
What is (are) Speech and Language Problems in Children ? | Children vary in their development of speech and language skills. Health professionals have milestones for what's normal. These milestones help determine if a child is on track or if he or she may need extra help. For example, a child usually has one or two words like "Hi," "dog," "Dada," or "Mama" by her first birthda... | 64 |
Does expression of p120-catenin isoforms correlate with genomic and transcriptional phenotype of breast cancer cell lines? | We demonstrate that mammary tumour cells exhibit a characteristic p120-catenin isoform expression profile, depending from their specific genomic and transcriptional properties. These particular expression patterns, combined with other regulatory proteins and in a specific cellular context, may explain how p120-catenin ... | 65 |
What is (are) Age-related Macular Degeneration ? | Dry AMD occurs when the light-sensitive cells in the macula slowly break down, gradually blurring central vision in the affected eye. As dry AMD gets worse, you may see a blurred spot in the center of your vision. Over time, as less of the macula functions, central vision in the affected eye can be lost. If you have vi... | 66 |
Does zinc deficiency aggravate abnormal glucose metabolism in thalassemia major patients? | These data support the assumption that zinc deficiency might lead to an exacerbation of the inability of the pancreas to secrete sufficient amounts of insulin in response to glucose stimulation in beta-thalassemia patients. We suggest that serum zinc levels be routinely monitored in these patients as it might provide u... | 67 |
Is Retinoblastoma inherited ? | Retinoblastoma occurs in heritable and nonheritable forms.
A child is thought to have the heritable form of retinoblastoma when one of the following is true: - There is a family history of retinoblastoma. - There is a certain mutation (change) in the RB1 gene. The mutation in the RB1 gene... | 68 |
Is the catechol O-methyltransferase Val158Met polymorphism associated with broad-based cognitive functioning in schizophrenia? | Based on the results in our sample, the catechol O-methyltransferase Val158Met polymorphism is not associated with broad-based cognitive functioning in schizophrenia. | 69 |
Does pET imaging of cortical 11C-nicotine binding correlate with the cognitive function of attention in Alzheimer 's disease? | Cortical nicotinic receptors in vivo in mild AD patients are robustly associated with the cognitive function of attention. | 70 |
Are melanoma metastases in regional lymph nodes accurately detected by proton magnetic resonance spectroscopy of fine-needle aspirate biopsy samples? | Proton MRS of FNAB samples may provide a robust and accurate diagnosis of metastatic disease in the regional lymph nodes of melanoma patients. These data indicate the potential for SN staging of melanoma without surgical biopsy and histopathological evaluation. | 71 |
What is (are) Wyburn Mason's syndrome ? | Wyburn Mason's syndrome is a condition in which blood vessels do not form correctly in both the retina of one eye and a part of the brain. These malformed blood vessels are called arteriovenous malformations (AVM). Wyburn Mason's syndrome is present from birth (congenital) and the cause is unknown. Individuals with ... | 72 |
What causes Lipodermatosclerosis ? | The exact cause of lipodermatosclerosis is unknown; however, it may be related to certain vein abnormalities and/or obesity. Lipodermatosclerosis often occurs in people with venous insufficiency. Approximately two thirds of affected people are obese. | 73 |
Is pIVKA-II a useful tumor marker for recurrent hepatocellular carcinoma after surgical resection? | Our data suggest that PIVKA-II is a useful tumor marker for HCC, complementary to AFP. Serial measurements of both markers after resection might be helpful for early diagnosis of tumor recurrence. | 74 |
What is (are) Levator syndrome ? | Levator syndrome is characterized by sporadic pain in the rectum caused by spasm of a muscle near the anus (the levator ani muscle). The muscle spasm causes pain that typically is not related to defecation. The pain usually lasts less than 20 minutes. Pain may be brief and intense or a vague ache high in the rectum. It... | 75 |
What is (are) Adult Acute Lymphoblastic Leukemia ? | Key Points
- Adult acute lymphoblastic leukemia (ALL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell). - Leukemia may affect red blood cells, white blood cells, and platelets. - Previous chemotherapy and exposure to radiation may increase th... | 76 |
Does intraluminal thyrotropin-releasing hormone affect gastric somatostatin and acid secretion through its specific receptor in rats? | These findings suggest that intraluminal TRH affects somatostatin and acid secretion in a paracrine manner via its specific receptor in the rat stomach. | 77 |
Does urinary oxalate excretion increase in home parenteral nutrition patients on a higher intravenous ascorbic acid dose? | In therapeutically used doses, IV vitamin C increases urinary oxalate excretion, potentially predisposing susceptible individuals to nephrolithiasis. This factor should be considered in patients receiving home TPN. | 78 |
What are the stages of Neuroblastoma ? | Key Points
- After neuroblastoma has been diagnosed, tests are done to find out if cancer has spread from where it started to other parts of the body. - There are three ways that cancer spreads in the body. - Cancer may spread from where it began to other parts of the body. - The following... | 79 |
Is subcutaneous efalizumab effective in the treatment of alopecia areata? | Numbers were too small for certain analyses. | 80 |
What is (are) Branchiootorenal syndrome ? | Branchiootorenal syndrome is characterized by birth defects or anomalies of tissues in the neck, malformations of the external ear, hearing loss, and kidney malformations. Symptom and symptom severity can vary greatly from person to person. It can be caused by mutations in the EYA1, SIX1, or SIX5 genes. It is passed th... | 81 |
How many people are affected by campomelic dysplasia ? | The prevalence of campomelic dysplasia is uncertain; estimates range from 1 in 40,000 to 200,000 people. | 82 |
What to do for Cystocele ? | - A cystocele, also called a prolapsed or dropped bladder, is the bulging or dropping of the bladder into the vagina. - A cystocele occurs when the muscles and supportive tissues between a womans bladder and vagina weaken and stretch, letting the bladder sag from its normal position and bulge into the vagina or throug... | 83 |
What are the treatments for Duchenne muscular dystrophy ? | There is no known cure for Duchenne muscular dystrophy (DMD). Treatment is aimed at the control of symptoms to maximize the quality of life. Individuals with DMD often experience dilated cardiomyopathy (the heart becomes larger and weaker). This can be treated with medications and in severe cases a heart transplant may... | 84 |
What is (are) epidermolysis bullosa simplex ? | Epidermolysis bullosa simplex is one of a group of genetic conditions called epidermolysis bullosa that cause the skin to be very fragile and to blister easily. Blisters and areas of skin loss (erosions) occur in response to minor injury or friction, such as rubbing or scratching. Epidermolysis bullosa simplex is one o... | 85 |
What is (are) Zellweger spectrum disorder ? | Zellweger spectrum disorder is a group of conditions that have overlapping signs and symptoms and affect many parts of the body. This group of conditions includes Zellweger syndrome, neonatal adrenoleukodystrophy (NALD), and infantile Refsum disease. These conditions were once thought to be distinct disorders but are n... | 86 |
Is juvenile Batten disease inherited ? | This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition. | 87 |
Is Tubular aggregate myopathy inherited ? | It is evident from family history studies that the condition can be passed through families in either an autosomal dominant or autosomal recessive fashion. Some cases appear to be due to dominant mutations in the STIM1 gene. Sporadic cases of tubular aggregate myopathy have also been reported. Sporadic is used to denot... | 88 |
What is (are) X-linked chondrodysplasia punctata 1 ? | X-linked chondrodysplasia punctata 1 is a disorder of cartilage and bone development that occurs almost exclusively in males. Chondrodysplasia punctata is an abnormality that appears on x-rays as spots (stippling) near the ends of bones and in cartilage. In most infants with X-linked chondrodysplasia punctata 1, this s... | 89 |
Does ketamine attenuate endotoxin-induced leukocyte adherence in rat mesenteric venules? | Pretreatment with ketamine attenuates endotoxin-induced leukocyte adherence by a shear rate-independent mechanism, suggesting reduced expression of adhesion molecules. These results indicate that ketamine exerts an anti-inflammatory effect, which might be beneficial in septic patients. | 90 |
Is toll-like receptor 2 required for autoantibody production and development of renal disease in pristane-induced lupus? | TLR-2 is required for the production of prototypical lupus autoantibodies and the development of renal disease in pristane-induced murine lupus. Interference with TLR-2 signaling may be a promising novel strategy for the treatment of SLE. | 91 |
What are the treatments for Neurosarcoidosis ? | There is no agreed upon standard of treatment for neurosarcoidosis. Doctors generally recommend corticosteroid therapy as first-line therapy for individuals with the condition. Additional treatment with immunomodulatory drugs such as hydroxychloroquine, pentoxyfilline, thalidomide, and infliximab, and immunosuppressive... | 92 |
What are the stages of Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies ? | Key Points
- Once childhood acute myeloid leukemia (AML) has been diagnosed, tests are done to find out if the cancer has spread to other parts of the body. - There is no standard staging system for childhood AML, childhood chronic myelogenous leukemia (CML), juvenile myelomonocytic leukemia (JM... | 93 |
What are the symptoms of Hereditary sensory and autonomic neuropathy type V ? | The Human Phenotype Ontology provides the following list of signs and symptoms for Hereditary sensory and autonomic neuropathy type V. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the defi... | 94 |
Is muscle atrophy as pre-sarcopenia in Japanese patients with chronic liver disease : computed tomography useful for evaluation? | Retrospective evaluate for pre-sarcopenia was easy to perform with CT findings. Nutrition and exercise instruction should be considered for early stage and even non-elderly CLD as well as LC. | 95 |
Is insecure attachment associated with paranoia but not hallucinations in psychotic patients : the mediating role of negative self-esteem? | It may be fruitful to explore attachment representations in psychological treatments for paranoid patients. If future research confirms the importance of disrupted attachment as a risk factor for persecutory delusions, consideration might be given to how to protect vulnerable young people, for example those raised in c... | 96 |
What are the genetic changes related to Horner syndrome ? | Although congenital Horner syndrome can be passed down in families, no associated genes have been identified. Horner syndrome that appears after the newborn period (acquired Horner syndrome) and most cases of congenital Horner syndrome result from damage to nerves called the cervical sympathetics. These nerves belong t... | 97 |
Does carbidopa pretreatment improve image interpretation and visualisation of carcinoid tumours with 11C-5-hydroxytryptophan positron emission tomography? | We conclude that CD premedication improves 11C-5-HTP PET image quality and facilitates detection of NET lesions. Because of the similarity of metabolic pathways, this method could probably be applied to improve PET imaging using other tracers like 18F-DOPA and 11C-DOPA. | 98 |
Is perioperative allogenenic blood transfusion associated with worse clinical outcomes for hepatocellular carcinoma : a meta-analysis? | The findings from the current meta-analysis demonstrated that ABT was associated with adverse clinical outcomes for HCC patients undergoing surgery, including increased death, recurrence and complications. Therefore, ABT should not be performed if possible. | 99 |
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