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11,600
Early cerebral thromboembolic complications after radiofrequency catheter ablation of atrial fibrillation: incidence, characteristics, and risk factors.
Thromboembolic complications remain one of the most severe adverse events associated with catheter ablation of atrial fibrillation (AF), but data on such events are limited.</AbstractText>The purpose of this study was to evaluate the incidence, characteristics, and risk factors of thromboembolic complications after AF ...
11,601
Vernakalant in an experimental model of pacing-induced heart failure: lack of proarrhythmia despite prolongation of repolarization.
The present ESC guidelines on atrial fibrillation have introduced vernakalant (VER) for pharmacologic cardioversion of atrial fibrillation. The aim of the present study was to investigate possible proarrhythmic effects of vernakalant in an experimental model of heart failure (HF).</AbstractText>In 12 female rabbits, HF...
11,602
Lack of interference of electromagnetic navigation bronchoscopy to implanted cardioverter-defibrillator: in-vivo study.
Electromagnetic navigation bronchoscopy (ENB) (Superdimension) is a diagnostic and therapeutic tool in patients with lung lesions. Very small data are available about potential interference of ENB magnetic field to implanted cardioverter-defibrillators (ICDs) and any documentation of ICD behaviour if a ventricular tach...
11,603
Is the acetylcholine-regulated inwardly rectifying potassium current a viable antiarrhythmic target? Translational discrepancies of AZD2927 and A7071 in dogs and humans.
We aimed at examining the acetylcholine-dependent inward-rectifier current (IKAch) as a target for the management of atrial fibrillation (AF).</AbstractText>The investigative agents AZD2927 and A7071 concentration-dependently blocked IKACh in vitro with minimal off-target activity. In anaesthetized dogs (n = 17) subjec...
11,604
Glucose fluctuations increase the incidence of atrial fibrillation in diabetic rats.
We investigated whether glucose fluctuations aggravate cardiac fibrosis and increase the occurrence of atrial fibrillation (AF) in rats with diabetes mellitus (DM).</AbstractText>Streptozotocin-induced diabetic rats were randomly divided into three groups: uncontrolled DM (U-STZ) group, controlled DM (C-STZ) group, and...
11,605
A prospective placebo controlled randomized study of caffeine in patients with supraventricular tachycardia undergoing electrophysiologic testing.
Patients with cardiac arrhythmias are generally instructed to avoid caffeine intake. A comprehensive evaluation of the electrophysiological effects of caffeine on atrial and ventricular tissues in humans has not previously been performed.</AbstractText>Eighty patients (31&#xa0;men, mean age 49&#xa0;&#xb1;&#xa0;14&#xa0;...
11,606
Acute Myocardial Infarction in Patient With Triple Negative Breast Cancer After Paclitaxel Infusion: A Case Report.
A 47-year-old woman with breast cancer suffered progressive chest pain and flushing within 5 minutes of her second exposure to paclitaxel. Her symptoms progressed and she became pulseless. Advanced cardiac life support (ACLS) was initiated, and after a series of chest compressions the cardiac monitor revealed ventricul...
11,607
Remote Monitoring for Follow-up of Patients with Cardiac Implantable Electronic Devices.
Follow-up of patients with cardiac implantable electronic devices is challenging due to the increasing number and technical complexity of devices coupled to increasing clinical complexity of patients. Remote monitoring (RM) offers the opportunity to optimise clinic workflow and to improve device monitoring and patient ...
11,608
New Ablation Technologies and Techniques.
Catheter ablation is an established treatment strategy for a range of different cardiac arrhythmias. Over the past decade two major areas of expansion have been ablation of atrial fibrillation (AF) and ventricular tachycardia (VT) in the context of structurally abnormal hearts. In parallel with the expanding role of ca...
11,609
Short QT Syndrome - Review of Diagnosis and Treatment.
Short QT syndrome (SQTS) is an inherited cardiac channelopathy characterised by an abnormally short QT interval and increased risk for atrial and ventricular arrhythmias. Diagnosis is based on the evaluation of symptoms (syncope or cardiac arrest), family history and electrocardiogram (ECG) findings. Mutations of cardi...
11,610
Left atrial reverse remodeling and prevention of progression of atrial fibrillation with atrial resynchronization device therapy utilizing dual-site right atrial pacing in patients with atrial fibrillation refractory to antiarrhythmic drugs or catheter ablation.
Dual-site right atrial pacing (DAP) produces electrical atrial resynchronization but its long-term effect on the atrial mechanical function in patients with refractory atrial fibrillation (AF) has not been studied.</AbstractText>Drug-refractory paroxysmal (PAF) and persistent AF (PRAF) patients previously implanted wit...
11,611
Cardiocerebral Resuscitation: An Approach to Improving Survival of Patients With Primary Cardiac Arrest.
Out-of-hospital cardiac arrest (OHCA) is a major public health problem. In the United States, OHCA accounts for more premature deaths than any other cause. For over a half-century, the national "Guidelines" for resuscitation have recommended the same initial treatment of primary and secondary cardiac arrests. Using thi...
11,612
Acute cardiogenic pulmonary edema--etiological spectrum and precipitating factors.
The analysis of the predisposing and precipitating factors encountered in the anamnesis of the patients hospitalized with acute pulmonary oedema, in order to establish some correlations with the evolution and prognosis.</AbstractText>The study included 50 patients, 32 males and 18 females, admitted to the Cardiology I ...
11,613
[Ventricular fibrillation or general seizure?].
A 78-year-old patient seemed to have recurrent seizures due to marginal hypoglycaemia. He was initially awake with stable circulation. Subsequently, he lost consciousness followed by extensie twitching arms of his arms and the upper part of his body. Thereafter, the patient was somnolent, but accessible.</AbstractText>...
11,614
Role of primary care physicians in treating patients with ST-segment elevation myocardial infarction located in remote areas (from the REseau Nord-Alpin des Urgences [RENAU], Network).
European guidelines for ST-segment elevation myocardial infarction (STEMI) encourage healthcare networks to increase rates of, and decrease delays to, reperfusion. We examined the impact of training primary care physicians (PCPs) to use equipment for pre-hospital management of STEMI patients in remote areas.</AbstractT...
11,615
Implication of left ventricular diastolic dysfunction in cryptogenic ischemic stroke.
Left ventricular diastolic dysfunction (LVDD) is a predictor for atrial fibrillation (AF). This study was aimed to investigate whether LVDD in cryptogenic ischemic stroke (CS) could be a clue to stroke mechanism.</AbstractText>The clinical and echocardiographic findings of 1589 consecutive patients with acute ischemic ...
11,616
Advances in clinical cardiology.
Multiple, potentially practice-changing cardiology trials have been presented or published over the past year. In this paper, we summarize and place in clinical context, new data regarding management of acute coronary syndrome and ST-elevation myocardial infarction (copeptin assessment, otamixaban, cangrelor, prasugrel...
11,617
Application of positron emission tomography in the detection of myocardial metabolism in pig ventricular fibrillation and asphyxiation cardiac arrest models after resuscitation.
To study the application of positron emission tomography (PET) in detection of myocardial metabolism in pig ventricular fibrillation and asphyxiation cardiac arrest models after resuscitation.</AbstractText>Thirty-two healthy miniature pigs were randomized into a ventricular fibrillation cardiac arrest (VFCA) group (n=...
11,618
Continuous rhythm monitoring for ventricular arrhythmias after alcohol septal ablation for hypertrophic cardiomyopathy.
The purpose of the present study was to determine the incidence of ventricular arrhythmias before and after alcohol septal ablation (ASA).</AbstractText>In patients with hypertrophic obstructive cardiomyopathy (HOCM), gradient reduction by ASA is an alternative for surgical myectomy. However, concerns exist about wheth...
11,619
Treatment of methadone-induced torsades de pointes with lidocaine.
Methadone maintenance treatment (MMT) is commonly used for chronic pain control and for substitution in heroin addicts undergoing rehabilitation. Methadone is known to prolong QT interval and sometimes cause torsade de pointes (TdP) and ventricular fibrillation (VF). Treatment of TdP by antiarrhythmic drugs that prolon...
11,620
Mid-term follow-up after maze IV procedures for concomitant atrial fibrillation.
We performed a retrospective analysis of the maze IV procedures performed in our surgical department for concomitant atrial fibrillation.</AbstractText>Preoperative, in-hospital and postoperative follow-up data were collected from 46 consecutive patients who underwent the maze IV operation between April 2006 and Decemb...
11,621
Coronary artery spasm following off-pump coronary artery bypass surgery.
Coronary artery spasm after coronary artery bypass surgery may result in life-threatening arrhythmias, circulatory collapse, or death. We report two cases of coronary artery spasm after coronary artery bypass surgery, one of which developed ventricular fibrillation requiring extracorporeal membrane oxygenation support....
11,622
Sevoflurane therapy for life-threatening acute severe asthma: a case report.
Acute severe asthma is a life-threatening form of bronchial constriction in which the progressively worsening airway obstruction is unresponsive to the usual appropriate bronchodilator therapy. Pathophysiological changes restrict airflow, which leads to premature closure of the airway on expiration, impaired gas exchan...
11,623
[Analysis of the cardiac side effects of antipsychotics: Japanese Adverse Drug Event Report Database (JADER)].
We analyzed the cases of side effects due to antipsychotics reported to Japan's Pharmaceuticals and Medical Devices Agency (PMDA) from Jan. 2004 to Dec. 2012. We used the Japanese Adverse Drug Event Report Database (JADER) and analyzed 136 of 216,945 cases using the defined terms. We also checked the cardiac adverse ef...
11,624
Ventricular fibrillation mechanisms and cardiac restitutions: An investigation by simulation study on whole-heart model.
The action potential duration (APD) and the conduction velocity (CV) restitution have been reported to be important in the maintenance and conversion of ventricular fibrillation (VF), whose mechanisms remain poorly understood. Multiple-wavelet and/or mother-rotor have been regarded as the main VF mechanisms, and APD re...
11,625
Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II: rationale and design of the ORBIT-AF II registry.
Recent clinical trials have demonstrated the safety and efficacy of several non-vitamin K oral anticoagulants (NOACs) for the treatment of atrial fibrillation (AF). However, there are limited data on their use and outcomes in routine clinical practice, particularly among patients newly diagnosed as having AF and patien...
11,626
Obesity does not increase complication rate of percutaneous epicardial access.
Percutaneous epicardial access for ablative therapies is an increasingly common technique utilized for refractory ventricular arrhythmias. There are, however few known data on obesity and complication rates associated with this procedure.</AbstractText>We retrospectively reviewed the charts of subjects undergoing epica...
11,627
Fosinopril improves the electrophysiological characteristics of left ventricular hypertrophic myocardium in spontaneously hypertensive rats.
This study investigated the effects of fosinopril on the electrophysiological characteristics of the left ventricular hypertrophic myocardium in spontaneously hypertensive rats (SHRs). Twenty-four 10-week-old male SHRs were divided into fosinopril and non-fosinopril groups (n&#x2009;=&#x2009;12 each). Twelve 10-week-ol...
11,628
Initial complications and factors related to prehospital mortality in acute myocardial infarction with ST segment elevation.
Hospital mortality in myocardial infarction ST-elevation myocardial infarction has decreased in recent years, in contrast to prehospital mortality. Our objective was to determine initial complications and factors related to prehospital mortality in patients with acute myocardial infarction with ST segment elevation (ST...
11,629
Sudden cardiac arrest in takotsubo cardiomyopathy - a case study.
We present a 59-year-old woman who was admitted to hospital after sudden cardiac arrest due to ventricular fibrillation. Finally takotsubo syndrome was diagnosed. In the acute phase of takotsubo syndrome life-threatening ventricular arrhythmias and significant hemodynamic disorders may occur due to strong adrenergic st...
11,630
Ventilation/perfusion ratios measured by multiple inert gas elimination during experimental cardiopulmonary resuscitation.
During cardiopulmonary resuscitation (CPR) the ventilation/perfusion distribution (VA /Q) within the lung is difficult to assess. This experimental study examines the capability of multiple inert gas elimination (MIGET) to determine VA /Q under CPR conditions in a pig model.</AbstractText>Twenty-one anaesthetised pigs ...
11,631
Optimal blood pressure in patients with atrial fibrillation (from the AFFIRM Trial).
Many medications used to treat atrial fibrillation (AF) also reduce blood pressure (BP). The relation between BP and mortality is unclear in patients with AF. We performed a post hoc analysis of 3,947 participants from the Atrial Fibrillation Follow-Up Investigation of Rhythm Management trial. Systolic blood pressure (...
11,632
Influence of the mode of management of acute myocardial infarction on the inducibility of ventricular tachyarrhythmias with programmed ventricular stimulation after myocardial infarction.
Programmed ventricular stimulation (PVS) is a technique for screening patients at risk for ventricular tachycardia (VT) after myocardial infarction (MI), but the results might be difficult to interpret.</AbstractText>To investigate the results of PVS after MI, according to date of completion.</AbstractText>PVS results ...
11,633
Detection of T-wave beat-by-beat variations prior to ventricular arrhythmias onset in ICD-stored intracardiac electrograms: the Endocardial T-Wave Alternans Study (ETWAS).
The aim of the Endocardial T-Wave Alternans Study was to prospectively assess the presence of T-wave alternans (TWA) or beat-to-beat repolarization changes on implantable cardioverter-defibrillator (ICD)-stored electrograms (EGMs) immediately preceding the onset of spontaneous ventricular tachycardia (VT) or fibrillati...
11,634
Regression of electrocardiographic left ventricular hypertrophy or strain is associated with lower incidence of cardiovascular morbidity and mortality in hypertensive patients independent of blood pressure reduction - A LIFE review.
Cornell product criteria, Sokolow-Lyon voltage criteria and electrocardiographic (ECG) strain (secondary ST-T abnormalities) are markers for left ventricular hypertrophy (LVH) and adverse prognosis in population studies. However, the relationship of regression of ECG LVH and strain during antihypertensive therapy to ca...
11,635
Wolff-Parkinson-White syndrome in the era of catheter ablation: insights from a registry study of 2169 patients.
The management of Wolff-Parkinson-White is based on the distinction between asymptomatic and symptomatic presentations, but evidence is limited in the asymptomatic population.</AbstractText>The Wolff-Parkinson-White registry was an 8-year prospective study of either symptomatic or asymptomatic Wolff-Parkinson-White pat...
11,636
SCN5A mutations and polymorphisms in patients with ventricular fibrillation during acute myocardial infarction.
Mutations in the SCN5A gene encoding the Nav1.5 channel &#x3b1;-subunit are known to be risk factors of arrhythmia, including Brugada Syndrome and Long QT syndrome subtype 3. The present study focused on the role of SCN5A variants in the development of ventricular fibrillation (VF) during acute myocardial infarction (A...
11,637
Complications in the clinical course of tako-tsubo cardiomyopathy.
This study evaluated the frequency, severity and outcome of complications in the clinical course of tako-tsubo cardiomyopathy (TTC).</AbstractText>TTC is regarded as a benign disease since left ventricular (LV) function returns to normal within a short time. However, severe complications have been reported in selected ...
11,638
Impact of adverse left ventricular remodeling on sudden cardiac death in patients with hypertrophic cardiomyopathy.
Adverse left ventricular (LV) remodeling predicts heart failure symptoms and overt LV dysfunction in patients with hypertrophic cardiomyopathy (HCM), but its influence on the occurrence of sudden cardiac death (SCD) is unknown. The aim of this study was to investigate the effect of adverse LV remodeling on SCD risk in ...
11,639
Distinct properties and metabolic mechanisms of postresuscitation myocardial injuries in ventricular fibrillation cardiac arrest versus asphyxiation cardiac arrest in a porcine model.
The two most prevalent causes of sudden cardiac death are ventricular fibrillation cardiac arrest (VFCA) and asphyxiation cardiac arrest (ACA). Profound postresuscitation myocardial dysfunction has been demonstrated in both VFCA and ACA animal models. Our study aimed to characterize the two porcine models of cardiac ar...
11,640
[Association between thyroid dysfunction and incidence of atrial fibrillation in patients with stable angina pectoris].
To explore the correlation between incidence of atrial fibrillation (AF) and thyroid dysfunction.</AbstractText>Patients with stable angina pectoris with thyroid function test results hospitalized at Fuwai Hospital from 2011 Jan to 2011 Dec were included in this analysis (n = 2 541). General clinical data and related b...
11,641
Study of spatial relationship of phrenic nerves with cardiac structures relevant to electrophysiologic interventions.
Pulmonary vein (PV) isolation with catheter ablation in treating atrial fibrillation carries the risk of injury to phrenic nerve (PN). Left PN (LPN) stimulation continues to be one of the common complications of transvenous left ventricular lead placement during cardiac resynchronization therapy (CRT).</AbstractText>In...
11,642
Arrhythmia risk assessment using heart rate variability parameters in patients with frequent ventricular ectopic beats without structural heart disease.
Ventricular ectopic beats (VEBs) are usually considered a benign condition that can be managed with conservative measures. Heart rate variability (HRV), which is one of the most important methods for assessing autonomic activity, is a noninvasive, quantitative method of analyzing autonomic effects on the heart. We aime...
11,643
Incident atrial fibrillation in systemic sclerosis: the predictive role of B-type natriuretic peptide.
Atrial fibrillation (AF) is common in patients with systemic sclerosis (SSc) and is associated with significant morbidity, mortality, and healthcare expenditures. The aim of this study was to prospectively determine the incidence and the independent predictors of AF in this patient population.</AbstractText>Forty-nine ...
11,644
Nonfluoroscopic catheter visualization in atrial fibrillation ablation: experience from 375 consecutive procedures.
A technological platform (MediGuide) has been recently introduced for nonfluoroscopic catheter tracking. No data on the safety of this technology are yet available in a large cohort of patients.</AbstractText>Data from a prospective ablation registry were analyzed. All patients undergoing atrial fibrillation ablation p...
11,645
New insights on Carpentier I mitral regurgitation from multidetector row computed tomography.
The underlying mechanism of mitral regurgitation (MR) because of isolated annulus dilation (Carpentier type I) remains controversial in patients with atrial fibrillation (AF). The present study evaluated changes in mitral valve geometry of patients with AF and structurally and functionally normal left ventricles and mi...
11,646
Altered RyR2 regulation by the calmodulin F90L mutation associated with idiopathic ventricular fibrillation and early sudden cardiac death.
Calmodulin (CaM) association with the cardiac muscle ryanodine receptor (RyR2) regulates excitation-contraction coupling. Defective CaM-RyR2 interaction is associated with heart failure. A novel CaM mutation (CaM(F90L)) was recently identified in a family with idiopathic ventricular fibrillation (IVF) and early onset s...
11,647
His bundle activates faster than ventricular myocardium during prolonged ventricular fibrillation.
The Purkinje fiber system has recently been implicated as an important driver of the rapid activation rate during long duration ventricular fibrillation (VF&gt;2 minutes). The goal of this study is to determine whether this activity propagates to or occurs in the proximal specialized conduction system during VF as well...
11,648
Left atrial functional reservoir: predictive value for outcome of catheter ablation in paroxysmal atrial fibrillation.
Left arial (LA) function, defined according to conduit, reservoir and booster functions, is closely linked to left ventricular (LV) mechanics, particularly during diastole. Right ventricular pacing (RVP) is thought to impair LA diastolic restoring forces through alteration of ventricular activation. The aim of this stu...
11,649
Comparison of intracardiac echocardiography and transesophageal echocardiography for imaging of the right and left atrial appendages.
Transesophageal echocardiography (TEE) is the standard for diagnosis of atrial thrombi and is performed before ablation of atrial arrhythmias. Intracardiac echocardiography (ICE) is routinely used during these procedures and may provide an alternative imaging modality.</AbstractText>The purpose of this study was to com...
11,650
Use of esmolol after failure of standard cardiopulmonary resuscitation to treat patients with refractory ventricular fibrillation.
We compare the outcomes for patients who received esmolol to those who did not receive esmolol during refractory ventricular fibrillation (RVF) in the emergency department (ED).</AbstractText>A retrospective investigation in an urban academic ED of patients between January 2011 and January 2014 of patients with out-of-...
11,651
Left atrial function in heart failure with impaired and preserved ejection fraction.
Left atrial structural and functional changes in heart failure are relatively ignored parts of cardiac assessment. This review illustrates the pathophysiological and functional changes in left atrium in heart failure as well as their prognostic value.</AbstractText>Heart failure can be divided into those with systolic ...
11,652
Clinical profile, management, and outcome in patients with out of hospital cardiac arrest: insights from a 20-year registry.
There is limited information regarding the clinical characteristics and outcome of out of hospital cardiac arrest (OHCA) in Middle Eastern patients. The aim of this study was to evaluate clinical characteristics, treatment, and outcomes in patients admitted following OHCA at a single center in the Middle East over a 20...
11,653
Failed anti-tachycardia pacing can be used to differentiate atrial arrhythmias from ventricular tachycardia in implantable cardioverter-defibrillators.
Atrial fibrillation/tachycardia (AF/AT) may result in inappropriate therapies in implantable cardioverter-defibrillators (ICDs). The post-pacing interval (PPI) and tachycardia cycle length difference (PPI - TCL) has been previously demonstrated to indicate the proximity of the pacing site to a tachycardia origin.</Abst...
11,654
Predictors of hospitalization for heart failure and of all-cause mortality after atrioventricular nodal ablation and right ventricular pacing for atrial fibrillation.
Atrioventricular junction ablation (AVJA) is a highly effective treatment in patients with therapy refractory atrial fibrillation (AF) but renders the patient pacemaker dependent. We aimed to analyse the long-term incidence of hospitalization for heart failure (HF) and all-cause mortality in patients who underwent AVJA...
11,655
Caspase-3-mediated splenic lymphocyte apoptosis in a porcine model of cardiac arrest.
Postresuscitation immunologic dysfunction contributes to the low survival rate after successful resuscitation, but its mechanism remains poorly understood. The mitochondrial apoptosis pathway is initiated by the Bcl-2/Bax-controlled and caspase-3-mediated pathway, this study investigated whether mitochondrial pathway-m...
11,656
Long-term outcomes after mitral valve repair for degenerative mitral regurgitation with persistent atrial fibrillation.
Atrial fibrillation (AF) adversely affects surgical outcomes of mitral valve surgery. However, the long-term impact of Maze procedure has not been clear yet.</AbstractText>We retrospectively investigated 159 patients who underwent mitral valve repair for degenerative mitral regurgitation with persistent AF between 1991...
11,657
Radiofrequency ablation of left atrial flutter mediated with double potentials in a seemingly normally structured heart.
Left atrial flutter (left AFL) is common in patients who undergo atrial fibrillation ablation and cardiac surgery; however, few reports describe left AFL in detail in a seemingly normally structured heart, and the mechanisms of the occurrence of such arrhythmia are still not clear. We describe left AFL in patients with...
11,658
A wavelet transform based feature extraction and classification of cardiac disorder.
This paper approaches an intellectual diagnosis system using hybrid approach of Adaptive Neuro-Fuzzy Inference System (ANFIS) model for classification of Electrocardiogram (ECG) signals. This method is based on using Symlet Wavelet Transform for analyzing the ECG signals and extracting the parameters related to dangero...
11,659
Outcomes of heart failure with preserved ejection fraction in a Southeast Asian cohort.
Heart failure with preserved ejection fraction (HF-PEF) has been shown to be of better or equivalent prognosis than heart failure with reduced ejection fraction (HF-REF). We aimed to characterize and study the outcome of HF-PEF in a multiethnic South East Asian context.</AbstractText>This is a single-centre retrospecti...
11,660
Therapeutic hypothermia in the intensive cardiac care unit.
Therapeutic hypothermia has demonstrated to improve both survival and neurological outcome in patients who experienced an out-of-hospital cardiac arrest. Nevertheless, many aspects of its clinical application are still controversial. Current guidelines recommend to cool patients who survive a cardiac arrest due to eith...
11,661
[Perioperative cardiovascular abnormality in elder patients with silent coronary heart disease].
To explore the perioperative cardiovascular dysfunction and its relevance to age in patients with silent coronary heart disease (or silent myocardial ischemia), and explore the clinical treatment and recovery of perioperative arrhythmias.</AbstractText>One hundred and eighty cases were selected from selective surgery p...
11,662
Prevalence of type 1 Brugada ECG pattern after administration of Class 1C drugs in patients with type 1 myotonic dystrophy: Myotonic dystrophy as a part of the Brugada syndrome.
Both type 1 myotonic dystrophy (MD1) and Brugada syndrome (BrS) may be complicated by conduction disturbances and sudden death. Spontaneous BrS has been observed in MD1 patients, but the prevalence of drug-induced BrS in MD1 is unknown.</AbstractText>The purpose of this study was to prospectively assess the prevalence ...
11,663
Resumption of chest compressions after successful defibrillation and risk for recurrence of ventricular fibrillation in out-of-hospital cardiac arrest.
Prior investigation of out-of-hospital cardiac arrest has raised the concern that ventricular fibrillation (VF) recurrence may be triggered by chest compression (CC) resumption. We investigated predictors of VF recurrence after defibrillation, including timing of CC resumption.</AbstractText>Patients with witnessed out...
11,664
A genome-wide association study to identify genomic modulators of rate control therapy in patients with atrial fibrillation.
For many patients with atrial fibrillation, ventricular rate control with atrioventricular (AV) nodal blockers is considered first-line therapy, although response to treatment is highly variable. Using an extreme phenotype of failure of rate control necessitating AV nodal ablation and pacemaker implantation, we conduct...
11,665
Late and very late drug-eluting stent thrombosis in the immediate postoperative period after antiplatelet withdrawal: a retrospective study.
Late (31-360 days after deployment) and very late (&gt;360 days after deployment) stent thrombosis is a feared complication after drug-eluting stent (DES) deployment. The American College of Cardiology/American Heart Association guidelines recommend dual antiplatelet therapy for 12 months due to the lack of protection ...
11,666
Impact of presenting rhythm on short- and long-term neurologic outcome in comatose survivors of cardiac arrest treated with therapeutic hypothermia.
To compare short- and long-term neurologic outcomes in comatose survivors of out-of-hospital cardiac arrest treated with mild therapeutic hypothermia presenting with nonshockable versus shockable initial rhythms.</AbstractText>Retrospective cohort study.</AbstractText>Emergency department and ICU of an academic hospita...
11,667
Ventricular arrhythmias in the North American multidisciplinary study of ARVC: predictors, characteristics, and treatment.
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is associated with sudden cardiac death. However, the selection of patients for implanted cardioverter-defibrillators (ICDs), as well as programming of the ICD, is unclear.</AbstractText>The objective of this study was to identify predictors, characteristics, and t...
11,668
Average current is better than peak current as therapeutic dosage for biphasic waveforms in a ventricular fibrillation pig model of cardiac arrest.
Defibrillation current has been shown to be a clinically more relevant dosing unit than energy. However, the effects of average and peak current in determining shock outcome are still undetermined. The aim of this study was to investigate the relationship between average current, peak current and defibrillation success...
11,669
Impact of intensified postresuscitation treatment on outcome of comatose survivors of out-of-hospital cardiac arrest according to initial rhythm.
We investigated the impact of intensified postresuscitation treatment in comatose survivors of out-of-hospital cardiac arrest (OHCA) of presumed cardiac etiology according to the initial rhythm at the emergency medical team arrival.</AbstractText>Interventions and survival with Cerebral Performance Category (CPC) 1-2 w...
11,670
High-fidelity simulation enhances ACLS training.
Medical student training and experience in cardiac arrest situations is limited. Traditional Advanced Cardiac Life Support (ACLS) teaching methods are largely unrealistic with rare personal experience as team leader. Yet Postgraduate Year 1 residents may perform this role shortly after graduation.</AbstractText>We expa...
11,671
Long-term results of single-procedure catheter ablation for atrial fibrillationin pre- and post-menopausal women.
To address whether menopause affects outcome of catheter ablation (CA) for atrial fibrillation (AF) by comparing the safety and long-term outcome of a single-procedure in pre- and post-menopausal women.</AbstractText>A total of 743 female patients who underwent a single CA procedure of drug-refractory AF were retrospec...
11,672
Incidence and outcome of re-entry injury in redo cardiac surgery: benefits of preoperative planning.
Repeat sternotomy for redo cardiac surgery may be associated with catastrophic injuries to mediastinal structures. The purpose of this study was to determine the frequency of these injuries, associated outcome and if a preoperative computerized tomography (CT) scan reduces the risk of re-entry injury.</AbstractText>Fiv...
11,673
Modified Valsalva manoeuvre to treat recurrent supraventricular tachycardia: description of the technique and its successful use in a patient with a previous near fatal complication of DC cardioversion.
Patients with attacks of re-entrant supraventricular tachycardia (SVT) frequently present to the emergency department (ED). The Valsalva manoeuvre (VM) is the most effective and safe vagal manoeuvre and advocated as the first-line treatment in stable patients but has a relatively low cardioversion success rate. Improvi...
11,674
Assessment of atrial conduction time in patients with polycystic ovary syndrome.
Polycystic ovary syndrome (PCOS) is closely related to increased cardiovascular risk in women of reproductive age. Atrial conduction abnormalities in these patients have not been investigated in terms of atrial electromechanical delay measured by tissue Doppler imaging (TDI) as an early predictor of atrial fibrillation...
11,675
Rationale and design of VENTURE-AF: a randomized, open-label, active-controlled multicenter study to evaluate the safety of rivaroxaban and vitamin K antagonists in subjects undergoing catheter ablation for atrial fibrillation.
To evaluate the safety of uninterrupted rivaroxaban, a novel oral anticoagulant that directly inhibits factor Xa, and a vitamin K antagonist (VKA) in eligible adult patients with nonvalvular AF (NVAF) who are scheduled for a catheter ablation.</AbstractText><AbstractText Label="METHODS/DESIGN" NlmCategory="METHODS">Thi...
11,676
Clinical and epidemiological profile of patients with valvular heart disease admitted to the emergency department.
To evaluate the clinical and epidemiological profile of patients with valvular heart disease who arrived decompensated at the emergency department of a university hospital in Brazil.</AbstractText>A descriptive analysis of clinical and echocardiographic data of 174 patients with severe valvular disease, who were clinic...
11,677
Effectiveness of atrial versus atrioventricular pacing for sick sinus syndrome during long-term follow-up.
According to the current guidelines, atrioventricular (DDD) pacing is superior to atrial pacing (AAI) in the treatment of sick sinus syndrome (SSS).</AbstractText>To compare outcomes of AAI and DDD pacing in patients with SSS during long-term follow-up.</AbstractText>We studied 809 patients, including 86 patients in th...
11,678
Delayed embolisation of amplatzer ASD closure device caused partial obstruction of left ventricular outflow tract.
A 54-year-old male presented with symptoms of dyspnoea, and oedema of the lower extremities. Transthoracic echocardiography (TTE) revealed secondum-type atrial septal defect (ASD). He successfully received a 30-mm Amplatzer ASD closure device percutaneously. Echocardiography immediately after the procedure and the next...
11,679
Simultaneous coronary artery bypass grafting and carotid endarterectomy can be performed with low mortality rates.
There is controversy over the best approach for patients with concomitant carotid and coronary artery disease. In this study, we report on our experience with simultaneous carotid endarterectomy (CEA) and coronary artery bypass graft (CABG) surgery in our clinic in the light of data in the literature.</AbstractText>Bet...
11,680
The potential mechanism of the detrimental effect of defibrillation prior to cardiopulmonary resuscitation in prolonged cardiac arrest model.
Defibrillation is no longer universally recommended as initial intervention for the reversal of ventricular fibrillation (VF) after a prolonged and untreated cardiac arrest. We sought to examine this issue in an animal model where a prolonged untreated VF was induced. The aim of this study was to investigate the potent...
11,681
Cardiovascular complications of calcium supplementation in chronic kidney disease: are there arrhythmic risks?
Calcium supplements may induce hypercalcaemia in patients with chronic kidney disease (CKD) or patients on hemodialysis. Even in the absence of overt hypercalcaemia, calcium supplementation may be associated with a positive calcium balance and intracellular calcium overload. There is an increased risk of complex suprav...
11,682
Anomalous origin of the right coronary artery from the pulmonary artery diagnosed in an adult: A case report.
Anomalous origin of the right coronary artery (ARCA) from the main pulmonary artery is a rare congenital anomaly, unlike the well-known anomalous origin of the left coronary artery (Bland-White-Garland syndrome) from the pulmonary artery. Since most ARCA cases are diagnosed during childhood, few adult cases have been r...
11,683
Hypertrophic cardiomyopathy: present and future, with translation into contemporary cardiovascular medicine.
Hypertrophic cardiomyopathy (HCM) is a common inherited heart disease with diverse phenotypic and genetic expression, clinical presentation, and natural history. HCM has been recognized for 55 years, but recently substantial advances in diagnosis and treatment options have evolved, as well as increased recognition of t...
11,684
Regional variations in baseline characteristics of cardiac rhythm device recipients: The PANORAMA observational cohort study.
The PANORAMA study was designed to collect concurrent data on subjects from different worldwide regions implanted with CRM devices.</AbstractText>In this prospective, multi-center study, we analyzed baseline data on 8586 subjects implanted with CRM devices with no additional selection criteria (66% pacemaker (IPG), 16%...
11,685
Cardiac arrest: should we consider norepinephrine instead of epinephrine?
A patient scheduled for a laparoscopic cholecystectomy had an anaphylactic shock during induction of anesthesia. After the injection of vecuronium, an unusual fall of arterial pressure occurred, with bradycardia, enlargement of the QRS complex, then a circulatory arrest. Chest compressions were initiated, while intrave...
11,686
[P wave dispersion increased in childhood depending on blood pressure, weight, height, and cardiac structure and function].
Increased P wave dispersion are identified as a predictor of atrial fibrillation. There are associations between hypertension, P wave dispersion, constitutional and echocardiographic variables. These relationships have been scarcely studied in pediatrics.</AbstractText>The aim of this study was to determine the relatio...
11,687
Electrocardiographic predictors of sudden and non-sudden cardiac death in patients with ischemic cardiomyopathy.
This study evaluated the prognostic value of electrocardiogram (ECG)-based predictors in the primary prevention of sudden cardiac arrest (SCA) among ischemic cardiomyopathy patients with depressed left ventricular ejection fraction (LVEF &#x2264;35%).</AbstractText>The prediction of cause-specific mortality in high-ris...
11,688
Predictive factors of left atrial spontaneous echo contrast in patients with rheumatic mitral valve stenosis: a retrospective study of 159 patients.
Mitral valve stenosis is a common manifestation of chronic rheumatic heart disease. The presence of spontaneous echo contrast in the left atrium and left atrial appendage has been reported to be an independent predictor of thrombo-embolic risk in patients with mitral stenosis. The objective of this study was to retrosp...
11,689
Early experience with the subcutaneous ICD.
The Subcutaneous Internal Cardiac Defibrillator (S-ICD) represents a major advance in the care of patients who have an indication for an internal cardiac defibrillator without pacing indications. Its main advantage is that it can deliver a shock to cardiovert ventricular arrhythmias utilising a tunnelled subcutaneous l...
11,690
Evaluation of the need of elective implantable cardioverter-defibrillator generator replacement in primary prevention patients without prior appropriate ICD therapy.
It is not clear whether patients who received an implantable cardioverter-defibrillator (ICD) for primary prevention should undergo device replacement if they never experienced an appropriate ICD therapy during the first generator longevity. This study evaluated the incidence and predictors of appropriate ICD therapy a...
11,691
Prognostic value of the electrocardiogram in patients with syncope: data from the group for syncope study in the emergency room (GESINUR).
The Group for Syncope Study in the Emergency Room (GESINUR) was a Spanish multicenter, prospective, observational study that evaluated the clinical presentation and acute management of loss of consciousness in Spain. Several studies have shown that an abnormal ECG is a poor prognostic factor in patients with syncope. H...
11,692
[Case with Emery-Dreifuss muscular dystrophy diagnosed forty-two years after onset and implanted with a cardiac resynchronization therapy defibrillator].
The patient was a 53-year-old male. He showed steppage gait at the age of 11 and equinus foot at 13. He walked unaided with shoe-insoles to support his heels. Atrial fibrillation and cardiac hypertrophy were found in his 30s, and ventricular tachycardia (VT) was observed at the age of 48. Electrophysiological studies w...
11,693
Arrhythmia and thyroid dysfunction.
Arrhythmia is a major cause of morbidity and mortality in Europe and in the United States. The aim of this review article was to assess the results of the prospective studies that evaluated the risk of arrhythmia in patients with overt and subclinical thyroid disease and discuss the management of this arrhythmia.</Abst...
11,694
Acute effects of simvastatin to terminate fast reentrant tachycardia through increasing wavelength of atrioventricular nodal reentrant tachycardia circuit.
Simvastatin (SV) leads to reduction of ventricular rhythm during atrial fibrillation on rabbit atrioventricular (AV) nodes. The aim of our study was (i) to determine the frequency-dependent effects of SV in a functional model, and (ii) to assess the effects of SV to suppress experimental AV nodal reentrant tachycardia ...
11,695
Circadian rhythm and day to day variability of serum potassium concentration: a pilot study.
Hyperkalemia is a common and life-threatening complication frequently seen in patients with acute kidney injury, end-stage renal disease and chronic heart failure. Cardiac arrest and ventricular fibrillation are possible consequences. Biosensors are currently being developed to measure serum potassium under ambulatory ...
11,696
[Catheter renal denervation in treatment of resistant hypertension: reality or fiction?].
Catheter renal denervation is one of the most dynamically emerging subspecialties in cardiology in the last five years. Initial indications for the treatment of resistant hypertension have been extended to other research areas - sleep apnea syndrome, heart failure, insulin resistance, atrial fibrillation, ventricular t...
11,697
Prognostic stratification of patients with chronic systolic heart failure using biomarkers and Doppler echocardiography.
To verify whether a combined assessment of left-ventricular filling pattern at Doppler echocardiography, plasma levels of brain natriuretic peptide (BNP) and high-sensitive troponin I (hsTnI) improves prognostic stratification in patients with chronic systolic heart failure.</AbstractText>Three predictors of prognosis ...
11,698
Polymorphisms of &#x3b2; 1-adrenoreceptor gene and cardiovascular complications in patients with thyrotoxicosis.
Human cardiac &#x3b2; 1-AR perform a crucial role in mediating the cardiostimulating effects of norepinephrine. Gly389Arg and Ser49Gly polymorphisms of &#x3b2; 1-adrenoreceptors ( &#x3b2; 1-AR) can influence the cardiovascular prognosis. However, the possible effect of Gly389Arg and Ser49Gly polymorphisms on heart func...
11,699
Long-term prognosis in patients with Brugada syndrome based on Class II indication for implantable cardioverter-defibrillator in the HRS/EHRA/APHRS Expert Consensus Statement: multicenter study in Japan.
The HRS/EHRA/APHRS Expert Consensus Statement for implantable cardioverter-defibrillator (ICD) in Brugada syndrome (BrS) has recently been published. However, the validity of the Class II indication for ICD in BrS patients is still unknown.</AbstractText>The purpose of this study was to evaluate the validity of the Cla...