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1,200 | Restitution properties during ventricular fibrillation in the in situ swine heart. | Although restitution has been hypothesized to determine action potential duration (APD) during ventricular fibrillation (VF), cardiac memory may also be important.</AbstractText>Transmembrane recordings were made with a floating microelectrode from the anterior right ventricular wall in 6 pigs during up to 60 seconds o... |
1,201 | Placebo-controlled, randomized clinical trial of azimilide for prevention of ventricular tachyarrhythmias in patients with an implantable cardioverter defibrillator. | Although implanted cardioverter defibrillators (ICDs) effectively treat sustained ventricular tachyarrhythmias, up to 50% of ICD recipients eventually require concomitant antiarrhythmic drug therapy to prevent symptomatic arrhythmia recurrences and hence reduce the number of device therapies.</AbstractText>A total of 6... |
1,202 | Is there a role for long-chain omega3 or oil-rich fish in the treatment of atrial fibrillation? | Atrial fibrillation is the most common cardiac arrhythmia in Europe and north America, and recently it was described as an epidemic. Treatment and management of this arrhythmia consists of using drugs, external electrical cardioversion and in extreme cases, internal electrical pacing. Despite treatment, this arrhythmia... |
1,203 | [Recurrent ventricular fibrillation during a febrile illness as the first manifestation of Brugada syndrome--a case report]. | A case of a 33-year-old male who was admitted to the hospital due to recurrent ventricular fibrillation during a febrile illness is presented. Initially, the patient was diagnosed with acute myocardial infarction and received thrombolytic treatment. Echocardiography and coronary angiography were normal. Right precordia... |
1,204 | In hospital cardiac arrest: a role for automatic defibrillation. | Sudden cardiac death (SCD) survival decreases by 10% for each minute of delay in defibrillation, however, survival rates of 98% can be achieved when defibrillation is accomplished within 30s of collapse. Recently, a fully automated external cardioverter-defibrillator (AECD) was approved by the FDA for in-hospital use. ... |
1,205 | Impact of community-wide deployment of biphasic waveform automated external defibrillators on out-of-hospital cardiac arrest in Taipei. | To determine the impact and outcome of out-of-hospital cardiac arrests (OHCA) while using automated external defibrillators (AED) with biphasic waveforms and its effectiveness when using the Utstein Style community-wide in Taipei.</AbstractText>A one-year study was conducted to collect OHCA patients with AED utilizatio... |
1,206 | Three year longitudinal study for out-of-hospital cardiac arrest in Osaka Prefecture. | To analyze the longitudinal changes in the treatment of out-of-hospital cardiac arrests. These analyses have focused on the time interval from the receipt of call until defibrillation of patients with ventricular fibrillation.</AbstractText>Population-based, prospective longitudinal study according to the Utstein style... |
1,207 | Prediction of short- and long-term outcomes by electrocardiography in survivors of out-of-hospital cardiac arrest. | Programs focusing on early defibrillation have improved both short- and long-term survival of patients with VF out-of-hospital cardiac arrest (OHCA). Subsequent long-term management of survivors would be facilitated by a straight-forward, non-invasive method of identifying those at highest risk for recurrence. Therefor... |
1,208 | Echocardiographic evidences of increased left ventricular pressure and atrial dilatation in patients with drug-resistant paroxystic atrial fibrillation and structurally normal heart. | Global myocardial index (GMI) has been significantly related to left ventricular filling pressure. We hypothesized that GMI and echographic indicators of atrial dilatation were significantly different in pAF pts compared to normals.</AbstractText>39 patients (pts) without structural heart disease, aged 52+/-10 years wi... |
1,209 | Haemoglobin level influences plasma brain natriuretic peptide concentration. | It has been demonstrated that the haemoglobin (Hb) level is associated with the prognosis of congestive heart failure (CHF). Correction of anaemia has improved CHF outcomes even in patients without anaemia. Lower Hb level may play a more important role in left ventricular (LV) dysfunction than previously recognized. Th... |
1,210 | Ventricular dysrhythmias in heart failure. | Left-ventricular systolic dysfunction, or heart failure (HF), is a chronic, progressive condition with a poor prognosis. Approximately 50% of deaths, especially in mild to moderate cases, are sudden. Most sudden deaths are thought to be due to ventricular tachycardia; however, premature ventricular contractions and cou... |
1,211 | Molecular and phenotypic effects of heterozygous, homozygous, and compound heterozygote myosin heavy-chain mutations. | Autosomal dominant familial hypertrophic cardiomyopathy (FHC) has variable penetrance and phenotype. Heterozygous mutations in MYH7 encoding beta-myosin heavy chain are the most common causes of FHC, and we proposed that "enhanced" mutant actin-myosin function is the causative molecular abnormality. We have studied ind... |
1,212 | [Excessive blood loss after abdominal hysterectomy -- use of recombinant factor VIIa]. | A 38-yr-old woman suffered from excessive blood loss after elective removal of the uterus because of a leiomyoma. The surgical attempt to stop the bleeding failed. The laboratory evaluation before surgery showed normal coagulation parameters (aPTT 23.4 sec, TPZ > 100 %, platelet count 267 000/microl).</AbstractText>... |
1,213 | Regression of significant tricuspid regurgitation after mitral balloon valvotomy for severe mitral stenosis. | Significant tricuspid regurgitation (TR) is occasionally associated with severe mitral stenosis and has an adverse impact on morbidity and mortality in patients undergoing mitral valve surgery. However, the effect of successful mitral balloon valvotomy (MBV) on significant TR is not fully elucidated. The aim of this st... |
1,214 | Role of a KCNH2 polymorphism (R1047 L) in dofetilide-induced Torsades de Pointes. | Various drugs are reported to prolong the QT-interval on the surface ECG, thereby increasing the risk of developing a potentially fatal arrhythmia known as Torsades de Pointes (TdP). TdP case reports for these drugs have often been associated with risk factors such as overdosing, concomitant drugs and/or existing patho... |
1,215 | [Fatal suicidal intoxication with cetirizine in patient with anorexia--a case report]. | According to the best of our knowledge this is the first case of acute fatal intoxication with cetirizine published in medical literature. We have described the case of a 18-year-old female with the history of anorexia for 2 years, who was admitted to Clinic of Toxicology because of suicidal attempt with use of cetiriz... |
1,216 | Heart failure, platelet activation and inhibition of the renin-angiotensin-aldosterone system. | Heart failure is a highly prevalent disease in aging western populations, associated with a substantially increased risk of thromboembolic events, not only in severe but even in mild to moderate stages. This can partly be attributed to concomitant atrial fibrillation, a well-known risk factor for stroke, as well as a "... |
1,217 | Epicardial mapping of chronic atrial fibrillation in patients: preliminary observations. | The mechanisms of chronic atrial fibrillation (AF) are not well understood. We performed epicardial mapping of chronic AF in patients undergoing open heart surgery to test the hypothesis that chronic AF is due to a left atrial "driver" with a regular, short cycle length, resulting in fibrillatory conduction to the rest... |
1,218 | Verification of implantable cardioverter defibrillator (ICD) interventions by nonlinear analysis of heart rate variability -- preliminary results. | Conventional ICD algorithms yield approximately 10-30% of spurious interventions. Our aim was to check whether nonlinear dynamics methods might be useful in the verification of ICD interventions.</AbstractText>We extracted 190 consecutive RR files (approximately 2000-9000 RR intervals long) from the ICDs of 70 patients... |
1,219 | An algorithm to predict implantable cardioverter-defibrillator lead failure. | The goal of this analysis was to test an algorithm that identifies implantable cardioverter-defibrillator (ICD) lead problems before clinical failure and/or inappropriate therapy.</AbstractText>The ICD lead failures typically present as inappropriate shock therapy. Identifying lead failures before their clinical presen... |
1,220 | Flecainide and propafenone induced ST-segment elevation in patients with atrial fibrillation: clue to specificity of Brugada-type electrocardiographic changes. | Potent sodium channel, blockade with type IC antiarrhythmics can provoke characteristic electrocardiographic changes consistent with Brugada's syndrome in unselected patients with atrial fibrillation. In 176 treated patients, the incidence of the characteristic abnormality is small (2.3%), and thus although no ventricu... |
1,221 | [Pharmacotherapy of chronic heart failure in clinical practice]. | Chronic heart failure affects between 1-5% of the population and rise steeply with age. Most patients with chronic heart failure should be routinely managed with a combination of 4 types of drugs: a diuretic, an angiotensin converting enzyme inhibitors (ACE-I), beta-blocker and usually digitalis. Diuretics are essentia... |
1,222 | Hemoperfusion in a child with amitriptyline intoxication. | Tricyclic antidepressant overdose is one of the most common causes of serious drug poisoning in children and adults. We report a 17-month-old girl with severe amitriptyline intoxication. She was admitted to hospital because of lethargy and seizures. It was estimated that she took approximately 75 mg/kg of amitriptyline... |
1,223 | Cardiac surgery for arrhythmias. | Cardiac arrhythmia surgery was initiated in 1968 with the first successful division of an accessory AV connection for the Wolff-Parkinson-White Syndrome. Subsequent surgical procedures included the left atrial isolation procedure and the right atrial isolation procedure for automatic atrial tachycardias, discrete cryos... |
1,224 | Comparison of primary mitral valve disease in German Shepherd dogs and in small breeds. | The case records of 58 German Shepherds (GS group) affected by mitral valve prolapse (MVP) and/or mitral valve regurgitation (MR), and 49 dogs weighing < 15 kg (D group), affected by chronic valvular disease (CVD) were reviewed. The dogs of the GS group were presented more often without a detectable heart murmur (p ... |
1,225 | Anterior ischemic optic neuropathy following off-pump cardiac bypass surgery. | Anterior ischemic optic neuropathy (AION) is a well-described cause of visual loss in patients who have undergone cardiac surgery with cardiopulmonary bypass. The etiology of AION following cardiac surgery with cardiopulmonary bypass is believed to be multifactorial. Microembolisation and pump-related platelet dysfunct... |
1,226 | Partial translocation for repair of left ventricular rupture after mitral valve replacement. | A new partial translocation technique to repair left ventricular rupture after mitral valve replacement and reimplant a mitral prosthesis is described. We repaired a tear from the interior by using mattress stitches buttressed with strips of Dacron felt, constructed a new annulus with a crescent-shaped piece of bovine ... |
1,227 | Regurgitation of the native aortic valve caused by thrombus formation after heterotopic heart transplantation. | A 61-year-old man, who had undergone heterotopic heart transplantation, had severe regurgitation through his native aortic valve develop 16 years later, which caused severe heart failure. At operation the regurgitation was found to be due to development of an organized thrombus in the sinuses of Valsalva tethering aort... |
1,228 | [Prevalence of atrial fibrillation and relationed factors in a population in the centre Madrid]. | Atrial fibrillation is the most common arrhythmia on clinical practice and an important risk factor for ictus. The aim of this study was to know the prevalence of this arrythmia in a central district of Madrid.</AbstractText>A retrospective study was done analysing medical records of 13,945 patients belonging to a prim... |
1,229 | [Alpha-linolenic acid and cardiovascular diseases]. | IMPORTANCE AND METABOLISM OF ALPHA-LINOLENIC ACID: Alpha-linolenic acid is an essential fatty acid which cannot be produced in the body and must be taken by food. Both in animals and humans, alpha-linolenic acid is desaturated and elongated into eicosapentaenoic and docosahexaenoic acid. It is also incorporated into pl... |
1,230 | Electrocardiographical case. Asymptomatic patient with ST-segment elevation. | A 46-year-old man complained of recurrent episodes of giddiness which was not associated with chest pain or breathlessness. There was no family history of sudden death. Clinical examination was unremarkable.12-lead electrocardiogram (ECG) showed ST segment elevation in the right precordial leads, with coved ST segment ... |
1,231 | [Pharmacological versus invasive treatment in patients with atrial fibrillation]. | Aim of this prospective study was to assess quality of life (QoL), left ventricular (LV) function and exercise performance in two groups of patients (pts) with atrial fibrillation (Af) treated with: radiofrequency catheter ablation (RFA) and antiarrhythmic drugs (AA). Between 1996 and 2000 - 74 patients, 28 women, with... |
1,232 | Beta1-adrenergic blockade during cardiopulmonary resuscitation improves survival. | The short-acting beta1-selective adrenergic blocking agent, esmolol, was administrated during cardiopulmonary resuscitation with the hypothesis that initial resuscitation and postresuscitation survival would be improved.</AbstractText>Prospective, randomized, controlled study.</AbstractText>Animal research laboratory.<... |
1,233 | Recurrent ventricular fibrillation in out-of-hospital cardiac arrest after defibrillation by police and firefighters: implications for automated external defibrillator users. | To determine the prevalence and frequency of recurrent ventricular fibrillation (VF) in patients defibrillated by police and firefighters only and to determine its relation to survival.</AbstractText>Retrospective observational study.</AbstractText>Out of hospital.</AbstractText>Individuals with witnessed VF arrest in ... |
1,234 | Vasopressin during cardiopulmonary resuscitation: a progress report. | In patients undergoing cardiopulmonary resuscitation, circulating endogenous vasopressin concentrations were significantly higher in successfully resuscitated patients than in patients who died. These observations have prompted several investigations to assess the role of vasopressin to improve cardiopulmonary resuscit... |
1,235 | Effect of vasopressin on postresuscitation ventricular function: unknown consequences of the recent Guidelines 2000 for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. | To compare the effect on postresuscitation left ventricular function of vasopressin vs. epinephrine used during cardiopulmonary resuscitation in a swine model of prolonged prehospital ventricular fibrillation.</AbstractText>Prospective, randomized experimental study.</AbstractText>University large animal resuscitation ... |
1,236 | Nonselective beta-blocking agent improves the outcome of cardiopulmonary resuscitation in a rat model. | Postresuscitation myocardial dysfunction has been recognized as a leading cause of early death after initial successful resuscitation. Recent experimental and clinical studies have indicated that the beta-adrenergic effect of epinephrine significantly increases the severity of postresuscitation myocardial dysfunction. ... |
1,237 | A new method for inducing hypothermia during cardiac arrest. | It has been shown that hypothermia induced after successful resuscitation of comatose survivors of ventricular fibrillation cardiac arrest improves survival and neurologic function. Recent studies also suggest that earlier induction of hypothermia may yield even more improvement. We sought to determine if a new pump sy... |
1,238 | Effects of intracerebroventricular application of brain-derived neurotrophic factor on cerebral recovery after cardiac arrest in rats. | After transient global cerebral ischemia, selective vulnerable brain areas show delayed neurodegeneration with characteristics of apoptosis. Recent data demonstrate potent neuroprotective effects of the application of endogenous growth hormones such as brain-derived neurotrophic factor (BDNF) after focal cerebral ische... |
1,239 | Amplitude spectrum area: measuring the probability of successful defibrillation as applied to human data. | The objective of our study was to examine the effectiveness of an electrocardiographic predictor, amplitude spectral area (AMSA), for the optimal timing of defibrillation shocks in human victims of cardiac arrest. Based on the spectral characteristics of ventricular fibrillation potentials, we examined the probability ... |
1,240 | Attenuated adult biphasic shocks for prolonged pediatric ventricular fibrillation: support for pediatric automated defibrillators. | To evaluate published data regarding the treatment of prolonged pediatric defibrillation, with special emphasis on the use of attenuated adult biphasic shocks for pediatric defibrillation.</AbstractText>Review relevant human and animal literature.</AbstractText>Rhythm analysis algorithms from two manufacturers of autom... |
1,241 | [Catheter cryoablation for the treatment of supraventricular arrhythmias]. | Catheter ablation is a radical treatment for various severe and drug-refractory arrhythmias. Radiofrequency is the reference energy for ablation, but has some limitations. Cryoenergy gradually freezes myocardial tissue, allowing the consequences to be predicted before inducing the lesion. Furthermore, the lesions are b... |
1,242 | Refractory ventricular fibrillation in accidental hypothermia: salvage with cardiopulmonary bypass. | A 20-year old woman presented with prolonged refractory ventricular fibrillation and pulmonary oedema following hypothermia while she was under self-administered heroin in an attempt to commit suicide. She was successfully resuscitated with cardiopulmonary bypass for core rewarming and internal defibrillation. |
1,243 | Use of implantable cardioverter defibrillators after out-of-hospital cardiac arrest: a prospective follow-up study. | Survivors of out-of-hospital cardiac arrest are at high risk of recurrent arrests, many of which could be prevented with implantable cardioverter defibrillators (ICDs). We sought to determine the ICD insertion rate among survivors of out-of-hospital cardiac arrest and to determine factors associated with ICD implantati... |
1,244 | Effects of cardiac resynchronization on disease progression in patients with left ventricular systolic dysfunction, an indication for an implantable cardioverter-defibrillator, and mildly symptomatic chronic heart failure. | The effects of cardiac resynchronization therapy (CRT) in patients with mildly symptomatic heart failure have not been fully elucidated.</AbstractText>The Multicenter InSync ICD Randomized Clinical Evaluation II (MIRACLE ICD II) was a randomized, double-blind, parallel-controlled clinical trial of CRT in NYHA class II ... |
1,245 | [Role of transthoracic echocardiography in evaluation of cardiac risk in thoracic surgery]. | It is not precisely defined which group of non-cardiac surgery patients should undergo transthoracic echocardiography in preoperative preparation. This study was prospectively performed to find out whether the routine use of echocardiography is justified in patients scheduled for lung resection, and to assess its role ... |
1,246 | Echo-guided endomyocardial biopsy in heart transplant recipients. | After heart transplantation the effect of immunosuppression is monitored by histopathology of endomyocardial biopsy (EMB). EMB is usually carried out under X-ray guidance. Between January 1998 and March 2003, 1,262 biopsies were collected under echo-guidance in 156 patients. The biopsy access was gained through the int... |
1,247 | Noninvasive assessment of right atrial pressure using Doppler tissue imaging. | Right atrial pressure (RAP) reflects volume and pressure hemodynamics of right cardiac chambers. Previous attempts for noninvasive assessment of RAP include 2-dimensional and Doppler correlates of RAP, which require the presence of optimal subcostal views that may not be always feasible. In this study we utilized Doppl... |
1,248 | Clinical significance of electrocardiography recordings from a higher intercostal space for detection of the brugada sign. | The significance of higher intercostal space electrocardiography (HICS ECG) for the detection of the Brugada sign was investigated.</AbstractText>The subjects consisted of 113 cases (108 males, 5 females; mean age, 57+/-17 years) with incomplete right bundle branch block type QRS morphology and ST-segment elevation (&g... |
1,249 | A benefit-risk assessment of class III antiarrhythmic agents. | The prevalence of arrhythmia in the population is increasing as more people survive for longer with cardiovascular disease. It was once thought that antiarrhythmic therapy could save life, however, it is now evident that antiarrhythmic therapy should be administrated with the purpose of symptomatic relief. Since many p... |
1,250 | [The effects of Na+ -H+ exchange inhibitor, KB-R9032, administered at the time of reperfusion in perfused rat heart]. | We have reported that pretreatment with KB-R9032, a newly developed Na+ -H+ exchange inhibitor is protective against reperfusion-induced ventricular arrhythmia in the isolated perfused rat heart. This study was conducted to elucidate whether the drug is equally effective when it is given at the time of reperfusion.</Ab... |
1,251 | [Antiischemic and antiarrhythmic effect of esafosfina]. | Esafosfina, a new preparation based on fructose 1,6-diphosphate, supported the pumping ability of the heart in experiments with a 40-min occlusion followed by 60-min reperfusion of the anterior descending branch of the left coronary artery in anesthetized cats. Esafosfina also exhibited a pronounced antifibrillatory an... |
1,252 | Biventricular support with the Jarvik 2000 ventricular assist device in a calf model of pulmonary hypertension. | The Jarvik 2000 ventricular assist device (VAD) is clinically efficacious for treating end-stage left ventricular failure. Because simultaneous right ventricular support is also occasionally necessary, we developed a biventricular Jarvik 2000 technique and tested it in a calf model. One VAD was implanted in the left ve... |
1,253 | Atrial fibrillation after electrical shock: a case report and review. | A 52 year old man was admitted to an emergency department with a fast ventricular rate atrial fibrillation after an electrical shock. Electrical cardioversion was attempted after echocardiographic examination. This failed, but the heart rate slowed. Successful pharmacological cardioversion was achieved after 16 hours o... |
1,254 | Effects of trimetazidine on myocardial preconditioning in anesthetized rats. | Trimetazidine is a widely used anti-ischemic agent, but its effect on myocardial preconditioning in anesthetized animals has not been investigated. The aim of this study was to examine the effects of trimetazidine on ischemic preconditioning and carbachol preconditioning in anesthetized rats. Ischemic preconditioning, ... |
1,255 | Mitral Regurgitation: Current Treatment Options and Their Selection. | Mitral regurgitation (MR) is a mechanically complex hemodynamic abnormality of various etiologies that, if untreated, leads to myocardial dysfunction, heart failure, and sudden death. Unless hemodynamically severe, MR is not a major risk factor for debility and death. However, even more modest MR may impact on longevit... |
1,256 | Approach to Hypertrophic Cardiomyopathy. | Hypertrophic cardiomyopathy is a genetic disease characterized by marked left ventricular (LV) hypertrophy. A dynamic LV outflow obstruction is present in approximately 20% of patients. Many affected individuals remain asymptomatic throughout life, others develop heart failure symptoms or atrial fibrillation (AF), and ... |
1,257 | [Cardiac indications for oral anticoagulation]. | While considering long-term oral anticoagulation one should assess benefit (i.e., reduction in thromboembolic events) and risks (i.e., bleeding complications) associated with therapy for each individual patient. The classic cardiac indications for oral anticoagulation include chronic atrial fibrillation, prosthetic hea... |
1,258 | Wolff-Parkinson-White syndrome: essentials for the primary care nurse practitioner. | To provide nurse practitioners with a basic understanding of the pathophysiology, clinical characteristics, diagnostic methods, and management of Wolff-Parkinson-White (WPW) syndrome.</AbstractText>Selected research and clinical articles.</AbstractText>WPW syndrome is the most common form of ventricular preexcitation. ... |
1,259 | Brain natriuretic peptide predicts successful cardioversion in patients with atrial fibrillation and maintenance of sinus rhythm. | Brain natriuretic peptide (BNP) is released from the heart by hemodynamically induced muscle stretch. Patients with atrial fibrillation have higher levels of BNP than those in sinus rhythm.</AbstractText>To assess the usefulness of BNP as a predictor of successful cardioversion in patients with persistent atrial fibril... |
1,260 | [Anti-arrhythmic effect of starfish sterol]. | To study the effect of modified starfish sterol [C03, succinic acid (5-epiandroene-17-one-3beta-ol) diester] on experimental arrhythmias.</AbstractText>Arrhythmias were induced by drugs (Aco, Oua, BaCl2 and adrenalin) i.v., ligating the left anterior descending coronary artery and electricity.</AbstractText>C03 71.4 mg... |
1,261 | [Case report of an unusual complication. Splenic rupture after cardiopulmonary resuscitation and thrombolysis resulted in death]. | Cardiopulmonary resuscitation (CPR) is associated with certain bleeding risks especially if thrombolysis is included in the treatment. Even though these risks are known it is not a contraindication with CPR after thrombolysis or thrombolysis after CPR. We present a case of a bleeding ruptured spleen after thrombolysis ... |
1,262 | Prospective randomized multicenter trial of empirical antitachycardia pacing versus shocks for spontaneous rapid ventricular tachycardia in patients with implantable cardioverter-defibrillators: Pacing Fast Ventricular Tachycardia Reduces Shock Therapies (PainFREE Rx II) trial results. | Successful antitachycardia pacing (ATP) terminates ventricular tachycardia (VT) up to 250 bpm without the need for painful shocks in implantable cardioverter-defibrillator (ICD) patients. Fast VT (FVT) >200 bpm is often treated by shock because of safety concerns, however. This prospective, randomized, multicenter t... |
1,263 | [Structural modification and bioactivity of cyclovirobuxine D]. | To search for new compounds for the treatment of cardiovascular diseases by structural modification of cyclovirobuxine D.</AbstractText>According to rational drug design principle, a series of cyclovirobuxine D analogues were prepared, and their bioactivities were tested.</AbstractText>Ten new compounds were syntheized... |
1,264 | Temporal and spatial phase analyses of the electrocardiogram stratify intra-atrial and intra-ventricular organization. | We hypothesized that electrocardiogram (ECG) spatial phase analysis would define a spectrum of intracardiac organization from atrial fibrillation (AF), nonisthmus-dependent and isthmus-dependent atrial flutter (AFL) to supraventricular tachycardias (SVT), and similarly for ventricular arrhythmias. We analyzed arrhythmi... |
1,265 | Exercise-provoked bidirectional ventricular tachycardia in a young woman. | Exercise-induced ventricular tachycardia (VT) is rare in children and young adults without structural heart disease. Catecholaminergic polymorphic VT (CPVT) is among the possible causes and carries a poor prognosis. The QRS morphology of CPVT can be bidirectional, polymorphic or even ventricular fibrillation. We report... |
1,266 | [Stroke and other tromboembolic complications in atrial fibrillation. Part I. Prevalence and risk factors]. | In a series of papers the authors discuss problems of epidemiology and drug prevention of stroke and other thromboembolic complications in patients with atrial fibrillation. Part I contains data on frequency of strokes in different categories of patients as well as review of main risk factors and mechanisms of developm... |
1,267 | [Simple cardiovascular reflex test during hospitalization due to myocardial infarction predicts sudden but not non-sudden cardiac death during 2 years follow up]. | Prognostic significance of heart rate (HR) response to easy to perform provocative maneuvers such as Valsalva maneuver and deep breath requires further elucidation.</AbstractText>Valsalva maneuver with calculation of Valsalva ratio (VR) and deep breath test with calculation of difference between average maximal and min... |
1,268 | Ephedrine increases ventricular arrhythmias in conscious dogs after myocardial infarction. | This study examined the hypothesis that the sympathomimetic activity of ephedrine increases the risk of lethal arrhythmias.</AbstractText>The sympathomimetic amine, ephedrine, is used to augment physical performance and as a weight loss aid, but little is known about the cardiovascular consequences in individuals with ... |
1,269 | Safety of dobutamine stress transesophageal echocardiography in obese patients for evaluation of potential ischemic heart disease. | The purpose of this study was to determine the safety of dobutamine stress transesophageal echocardiography (DS-TEE) in the evaluation of potential coronary artery disease in obese patients. Obese patients tend to have a higher prevalence of hypertension, coronary artery disease, and sleep apnea conditions that could p... |
1,270 | Deaths due to hunger strike: post-mortem findings. | Hunger strike is described as voluntary refusal of food and/or fluids. Prolonged starvation may produce many adverse events including even death in rare circumstances. Here, we present three fatal cases (all males, 25-38 years) died from hunger strike. In all corpses, obvious muscle wasting with reduced subcutaneous an... |
1,271 | Association of stage of left ventricular diastolic dysfunction with P wave dispersion and occurrence of atrial fibrillation after first acute anterior myocardial infarction. | The aim of this study was to investigate the association of stage of left ventricular diastolic dysfunction after acute myocardial infarction (AMI) with P maximum, P dispersion, and atrial fibrillation (AF) occurrence rate.</AbstractText>The occurrence of AF following AMI is frequently associated with a left ventricle ... |
1,272 | Two hearts and one defibrillator. | A patient who had undergone heterotopic heart transplantation and placement of an implantable cardioverter defibrillator in his native heart underwent generator change. Defibrillation testing induced ventricular fibrillation in his donor heart. To prevent this potentially lethal complication, defibrillator shock therap... |
1,273 | Adaptation of cardiac action potential durations to stimulation history with random diastolic intervals. | The restitution hypothesis proposes that adaptation of cardiac action potential duration (APD) to rate changes is a predictor of ventricular fibrillation (VF). Conventional restitution kinetics plots the APD of a premature beat as a function of the previous diastolic interval (DI), and VF vulnerability is related to ho... |
1,274 | Effects of ablation, digitalis, and beta-blocker on dual atrioventricular nodal pathways and conduction during atrial fibrillation. | Modification of AV nodal conduction by radiofrequency ablation (RFA) results in a variable reduction in heart rate during atrial fibrillation (AF). Using AF induced in patients with dual AV nodal pathways as a model, we tested the effect of additional treatment with digitalis (ouabain) and beta-blocker (esmolol).</Abst... |
1,275 | Magnetic resonance imaging findings in patients with Brugada syndrome. | Cardiac magnetic resonance imaging (CMR) is a powerful diagnostic tool for evaluating cardiac structure and function. Recently, right ventricular wall-motion abnormalities were described using electron beam tomography in patients with Brugada syndrome. In the present study, we prospectively evaluated CMR findings in pa... |
1,276 | Presence of intermittent J waves in multiple leads in relation to episode of atrial and ventricular fibrillation. | Brugada syndrome is characterized by J wave and ST-segment elevation of right precordial leads and causes idiopathic ventricular fibrillation. We experienced a patient of Brugada syndrome with prominent J wave and ST-segment elevation not only in V(1) to V(3) but also in many leads. He suffered spontaneous ventricular ... |
1,277 | Mild hypothermia during prolonged cardiopulmonary cerebral resuscitation increases conscious survival in dogs. | Therapeutic hypothermia during cardiac arrest and after restoration of spontaneous circulation enables intact survival after prolonged cardiopulmonary cerebral resuscitation (CPCR). The effect of cooling during CPCR is not known. We hypothesized that mild to moderate hypothermia during CPCR would increase the rate of n... |
1,278 | Cooled ablation. | Research on cooled ablation has been evolving for the last 10 years. Findings and current applications are reviewed. A cooled ablation catheter is approved by the FDA for use in idiopathic ventricular tachycardia (VT) patients, based on data originally submitted by Cardiac Pathways, Inc. This technology has subsequentl... |
1,279 | Focal origin of ventricular fibrillation in a patient with ischemic cardiomyopathy. | A 65-year-old patient with history of ischemic cardiomyopathy admitted to the hospital for chest pain and subsequently experienced incessant ventricular fibrillation (VF), requiring repeated defibrillation. Coronary angiogram was unchanged, compared to a study a year before, and acute ischemia was not considered to be ... |
1,280 | IgD myeloma with systemic amyloidosis with chest discomfort as an initial symptom. | A 53-year-old man was admitted to Keio University Hospital because of serious dyspnea and edema of the lower extremities. Eighteen months previously, the patient had complained of chest discomfort, and was then admitted for the first time to our hospital for evaluation of chest pain. Electrocardiography showed poor R w... |
1,281 | Atrial fibrillation after surgical correction of mitral regurgitation in sinus rhythm: incidence, outcome, and determinants. | The incidence, determinants, and outcome of postoperative atrial fibrillation (AF) after surgery for mitral regurgitation (MR) are poorly defined but may have important implications for timing of mitral valve surgery.</AbstractText>In 762 patients in sinus rhythm with no AF history undergoing MR surgical correction, we... |
1,282 | Role of IKur in controlling action potential shape and contractility in the human atrium: influence of chronic atrial fibrillation. | The ultrarapid outward current I(Kur) is a major repolarizing current in human atrium and a potential target for treating atrial arrhythmias. The effects of selective block of I(Kur) by low concentrations of 4-aminopyridine or the biphenyl derivative AVE 0118 were investigated on right atrial action potentials (APs) in... |
1,283 | Effect of simvastatin and antioxidant vitamins on atrial fibrillation promotion by atrial-tachycardia remodeling in dogs. | There is evidence for a role of oxidant stress and inflammation in atrial fibrillation (AF). Statins have both antioxidant and antiinflammatory properties. We compared the effects of simvastatin with those of antioxidant vitamins on AF promotion by atrial tachycardia in dogs.</AbstractText>We studied dogs subjected to ... |
1,284 | Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirin. | The rate of stroke in atrial fibrillation (AF) depends on the presence of comorbid conditions and the use of antithrombotic therapy. Although adjusted-dose warfarin is superior to aspirin for reducing stroke in AF, the absolute risk reduction of warfarin depends on the stroke rate with aspirin. This prospective cohort ... |
1,285 | Absence of clinically important HERG channel blockade by three compounds that inhibit phosphodiesterase 5--sildenafil, tadalafil, and vardenafil. | Compounds that inhibit phosphodiesterase 5 (PDE5) have been developed for the treatment of erectile dysfunction. Because men with erectile dysfunction frequently have comorbid cardiovascular disease, they may have limited cardiac repolarization reserve and be at risk of arrhythmia if treated with medications that prolo... |
1,286 | Value of immediate postoperative electrocardiogram to update risk stratification after major noncardiac surgery. | Current consensus guidelines recommend postoperative electrocardiographic surveillance only in patients at relatively high risk of postoperative major cardiac complications, but the usefulness of electrocardiograms after major noncardiac surgery is unknown. We prospectively studied 3,570 patients who underwent major no... |
1,287 | Comparison of outcomes of white versus black patients hospitalized with heart failure and preserved ejection fraction. | Black patients who have heart failure (HF) may have a larger proportion of HF with preserved ejection fraction (PEF) than white patients because of the greater prevalence and severity of hypertension and left ventricular hypertrophy in blacks. However, studies have not systematically evaluated differences by race in pa... |
1,288 | Dysrhythmias and the athlete. | Young competitive athletes are perceived by the general population to be the healthiest members of society. The possibility that highly trained high school and college athletes may have a potentially serious cardiac condition that can predispose to life-threatening dysrhythmias or sudden cardiac death (SCD) seems parad... |
1,289 | Risk stratification and primary prevention of sudden cardiac death: sudden death prevention. | The initial challenge in primary prevention of sudden cardiac death (SCD) lies in identifying those at greatest risk, before the index event. Ventricular fibrillation is the leading cause of SCD; however, many clinical conditions predispose fatal ventricular dysrhythmias. In patients with structural heart disease, left... |
1,290 | Cardiac pacing device therapy for atrial dysrhythmias: how does it work? | Atrial fibrillation (AF) is the most common dysrhythmia in North America. Paroxysmal or persistent AF affects an estimated 2.8 million individuals, causes significant morbidity, and is associated with 1 billion dollars in healthcare costs each year in the United States. An aging population, the prevalence of hypertensi... |
1,291 | Cardiac defibrillation and resynchronization therapies: principles, therapies, and management implications. | Patients with heart failure remain at high risk for sudden cardiac death (SCD) and death due to heart failure progression, despite the incorporation of pharmacologic agents into clinical practice that have been shown to decrease mortality in clinical trials. Most patients experience SCD as their first dysrrhythmic even... |
1,292 | Myocarditis: emergency department recognition and management. | Myocarditis is an acute inflammatory syndrome involving the heart and related structures. In many instances, the presentation is obvious, and appropriate treatment and disposition follow accordingly. In other situations, patients present with viral illness of the respiratory or gastrointestinal tracts (or both) or nons... |
1,293 | Dimensionality in cardiac modelling. | The development of mathematical models of the heart has been an ongoing concern for many decades. The initial focus of this work was on single cell models that incorporate varyingly detailed descriptions of the mechanisms that give rise to experimentally observed action potential shapes. Clinically relevant heart rhyth... |
1,294 | Benefit-risk assessment of tolterodine in the treatment of overactive bladder in adults. | Overactive bladder is associated with symptoms of urgency, with or without urge incontinence, usually with daytime frequency and nocturia in the absence of local pathological factors. Muscarinic receptor antagonists (antimuscarinics) are the first-line pharmacotherapy. Tolterodine, a competitive, nonselective antimusca... |
1,295 | Mother rotors and the mechanisms of D600-induced type 2 ventricular fibrillation. | Two types of ventricular fibrillation (VF) have been demonstrated in isolated rabbit hearts during D600 infusion. Type 1 VF is characterized by the presence of multiple, wandering wavelets, whereas type 2 VF shows local spatiotemporal periodicity. We hypothesized that a single mother rotor underlies type 2 VF.</Abstrac... |
1,296 | Conditions leading to pediatric cardiology consultation in a tertiary academic hospital. | To determine the basis for cardiac consultations for pediatric patients in an academic hospital setting.</AbstractText>The activities of the cardiology consultation service were tabulated for 12 months, from July 2001 to June 2002. Patients were identified from 4 sources, ie, a monthly log of patient encounters maintai... |
1,297 | Simultaneous biplane single-beat assessment of left ventricular systolic function in patients with atrial fibrillation. | Left ventricular systolic function was studied in 40 patients with atrial fibrillation using a matrix-array transducer, which enables 2 simultaneous orthogonal views to be obtained in a biplane mode. Bland-Altman analysis showed excellent correlation and agreement between the systolic parameters of a single beat with i... |
1,298 | Effects of ventricular rate regularization pacing on quality of life and symptoms in patients with atrial fibrillation (Atrial fibrillation symptoms mediated by pacing to mean rates [AF SYMPTOMS study]). | The aim of this study was to investigate the effect of the Ventricular Response Pacing (VRP) algorithm, which regularizes ventricular rate during atrial fibrillation (AF), on symptoms, quality of life, and functional capacity. VRP regularizes the ventricular rate during AF without increasing the mean ventricular rate, ... |
1,299 | QT interval variability and spontaneous ventricular tachycardia or fibrillation in the Multicenter Automatic Defibrillator Implantation Trial (MADIT) II patients. | This study aimed to determine whether increased QT interval variability is associated with an increased risk for ventricular tachycardia (VT) or ventricular fibrillation (VF), documented by interrogation of the implantable cardioverter-defibrillator (ICD), in patients enrolled in the Multicenter Automatic Defibrillator... |
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