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1,000 | Predictive characteristics of holter-based postinfarction risk stratifiers appear superior to electrophysiological testing. | Prevalent low-frequency (PLF) oscillation of heart rate and turbulence slope (TS) are both powerful postmyocardial infarction (MI) risk factors. Abnormal composite risk stratifier (CRS) was defined as abnormal PLF or abnormal TS when PLF was not analyzable. We compared the predictive power of CRS with the previously pu... |
1,001 | Defibrillation effects of intravenous nifekalant in patients with out-of-hospital ventricular fibrillation. | Nifekalant (NF), a pure K(+) channel blocker developed in Japan, has been reported to be effective in the treatment of life-threatening ventricular arrhythmias. We studied its efficacy in 18 men and 4 women with out-of-hospital ventricular fibrillation (VF) admitted to our emergency department between August 2001 and M... |
1,002 | Detection of atrial fibrillation by implanted devices with wireless data transmission capability. | Remote telemetry may facilitate the management of implantable devices. We tested the reliability of a new automatic, wireless home monitoring (HM) system that archives data every 24 hours. We retrospectively analyzed archival data from 276 consecutive pacing system implants to define temporal atrial fibrillation (AF) p... |
1,003 | Serum troponin I and myoglobin after monophasic versus biphasic transthoracic shocks for cardioversion of persistent atrial fibrillation. | This study compared the effects of standard monophasic versus biphasic direct current shocks for cardioversion of atrial fibrillation (AF) on the release of cardiac troponin I (cTnI) and myoglobin (Myo). We randomized 48 patients with persistent AF (mean age = 61.4 +/- 10.7 years, 33 men) to monophasic (45.2%) or bipha... |
1,004 | No correlation between atrial natriuretic peptide concentrations and echocardiographic measurements of left atrial size or left ventricular size and function in patients with persistent atrial fibrillation. | Atrial fibrillation (AF) may be associated with activation of atrial natriuretic peptide (ANP). The exact trigger for the release of ANP is still being debated. Atrial volume, pressure, and wall stretch are considered to be the main determinants of ANP activation. The aim of the study was to evaluate plasma ANP concent... |
1,005 | [Treatment of life-threatening cardiac arrhythmias]. | Tachyarrhythmias represent a frequent problem in intensive care medicine. However, considerable uncertainty prevails among physicians regarding optimal pharmacotherapy, due also to numerous negative study results on chronic antiarrhythmic therapy. Moreover, in an emergency situation, the physician faces the dilemma of ... |
1,006 | Prevention of sudden cardiac death: the role of the implantable cardioverter-defibrillator. | Sudden cardiac death, usually due to fatal ventricular tachyarrhythmias, results in the loss of 300,000-400,000 lives each year in the United States. Implantable cardioverter-defibrillator therapy has revolutionized both the secondary and, increasingly, the primary prevention of sudden cardiac death. In the last decade... |
1,007 | N,N,N',N'-tetrakis(2-pyridylmethyl)-ethylenediamine improves myocardial protection against ischemia by modulation of intracellular Ca2+ homeostasis. | N,N,N',N'-Tetrakis(2-pyridylmethyl)-ethylenediamine (TPEN), a transition-metal chelator, was recently found to protect against myocardial ischemia-reperfusion injury. The goals of this study were to investigate the in vivo antiarrhythmic and antifibrillatory potential of TPEN in rats and guinea pigs and to study the in... |
1,008 | Successful resuscitation after sudden death in a one year old infant who sustained a blunt chest injury after a fall from 10 m. | Sudden cardiac arrest due to blunt anterior chest wall impact (Commotio Cordis) usually occurs in young athletes who are struck by a baseball or other projectile in the precordium. Survival is extremely rare if the induced ventricular fibrillation (VF) is not defibrillated immediately at the scene. We report here a rar... |
1,009 | Prehospital thrombolysis perfomed by a ship's nurse with on-line physician consultation. | Prehospital thrombolysis for acute ST-elevation myocardial infarction (STEMI) has been shown to improve recovery from myocardial function. We describe prehospital thrombolytic treatment in two patients suffering from STEMI complicated by ventricular fibrillation (VF) on a passenger ship. The importance of a functioning... |
1,010 | Influence of dobutamine on the variables of systemic haemodynamics, metabolism, and intestinal perfusion after cardiopulmonary resuscitation in the rat. | Global left ventricular dysfunction after successful resuscitation from cardiac arrest may be treated successfully with dobutamine but the effects on intestinal perfusion are unknown.</AbstractText>In 24 male Sprague-Dawley rats ventricular fibrillation was induced. After 4 min of untreated cardiac arrest, precordial c... |
1,011 | Effects of intravenous arginine vasopressin on epicardial coronary artery cross sectional area in a swine resuscitation model. | Although arginine vasopressin (AVP) has been shown to be a promising drug during cardiopulmonary resuscitation (CPR), concern has been raised about the potential for AVP-mediated vasoconstriction of the coronary arteries. In a prospective, randomized laboratory investigation employing an established porcine model, the ... |
1,012 | The evolution of serum astroglial S-100 beta protein in patients with cardiac arrest treated with mild hypothermia. | To study the effects of mild hypothermia on the 24h concentration of serum astroglial of S-100 beta protein in patients who survived cardiac arrest (CA).</AbstractText>A prospective, randomised, clinical study in a university teaching hospital.</AbstractText>Sixty-one resuscitated patients were randomised into two pros... |
1,013 | Layperson positioning of defibrillation electrodes guided by pictorial instructions. | Correct positioning of defibrillation electrodes is essential to achieve sufficient transmyocardial current to depolarize a critical mass of myocardium, and thus terminate ventricular fibrillation (VF).</AbstractText>To evaluate the pictures on the self-adhesive defibrillation electrodes in guiding laypersons to place ... |
1,014 | Evaluating the quality of prehospital cardiopulmonary resuscitation by reviewing automated external defibrillator records and survival for out-of-hospital witnessed arrests. | Without an easy method to monitor the performance of prehospital cardiopulmonary resuscitation (CPR), earlier studies have not been able to assess the quality of CPR. In this study, we have used a new approach to evaluate prehospital CPR performance and the impact on outcome using data retrieved from the automatic exte... |
1,015 | Emergency trans-oesophageal ventricular pacing in a child. | We report our experience with an 8-year-old boy with complete atrioventricular block and syncopal bradycardia who required urgent pacing. Each attempt to cross the tricuspid valve with a femoral lead triggered ventricular standstill, followed by fibrillation, and pacing through the coronary sinus failed. Successful ven... |
1,016 | Effects of transient myocardial ischemia on the ventricular defibrillation threshold. | Acute myocardial ischemia and the mode of ventricular fibrillation (VF) induction influence the ventricular defibrillation threshold (DFT).</AbstractText>The purpose of this study was to determine the effects of transient regional left ventricular (LV) ischemia on the DFT.</AbstractText>Ventricular effective refractory... |
1,017 | Thyrotoxic periodic paralysis complicated by near-fatal ventricular arrhythmias. | A 35-year-old Chinese man presented with acute thyrotoxic periodic paralysis complicated by near-fatal cardiac arrhythmias due to persistent hypokalaemia, despite maximum potassium supplementation. He was eventually resuscitated with external cadioversion. In this unusual case of severe refractory hypokalaemia leading ... |
1,018 | The burden of atrial fibrillation: should we abandon antiarrhythmic drug therapy? | Atrial fibrillation (AF) is the most common sustained arrhythmia, exacting a substantial toll in cardiovascular morbidity and mortality. Until recently, the prevailing philosophy has been that restoration and maintenance of normal sinus rhythm, as opposed to control of ventricular response rate, was the optimal approac... |
1,019 | C-reactive protein and microalbuminuria are associated with atrial fibrillation. | Atrial fibrillation (AF) is associated with an increased risk for cardiovascular disease. It is important to detect AF at an early stage and to search for new pathophysiological pathways to intervene. We hypothesized that microalbuminuria and C-reactive protein (CRP), a marker of generalized vascular damage and inflamm... |
1,020 | Improved resuscitation outcome in emergency medical systems with increased usage of sodium bicarbonate during cardiopulmonary resuscitation. | The use of sodium bicarbonate (SB) in cardiopulmonary resuscitation (CPR) is controversial. This study analyzes the effects of SB use on CPR outcome in the Brain Resuscitation Clinical Trial III (BRCT III), which was a multicenter randomized trial comparing high-dose to standard-dose epinephrine during CPR. Sodium bica... |
1,021 | CPR before defibrillation in out-of-hospital cardiac arrest: a randomized trial. | Current resuscitation guidelines recommend that defibrillation be undertaken as soon as possible in patients suffering a cardiac arrest where the cardiac rhythm is either ventricular fibrillation (VF) or ventricular tachycardia (VT). Evidence from animal and clinical studies suggests that outcomes may be improved if a ... |
1,022 | Gender differences in electrophysiologic effects of mental stress and autonomic tone inhibition: a study in health individuals. | Gender differences exist in electrophysiologic properties and the occurrence of certain arrhythmias. Mental stress may trigger serious arrhythmias, including ventricular tachycardias and ventricular fibrillation. This study investigates gender differences in the electrophysiologic effects on different levels of the car... |
1,023 | Further insights into the effect of quinidine in short QT syndrome caused by a mutation in HERG. | The principal aim of this study was to assess the efficacy of quinidine in suppressing IKr in vitro and in modulating the rate dependence of the QT interval in the "SQT1" form of the short QT syndrome.</AbstractText>Graded-intensity bicycle exercise testing was performed off drug in three patients and during oral quini... |
1,024 | Assessment of markers for identifying patients at risk for life-threatening arrhythmic events in Brugada syndrome. | Risk stratification for life-threatening arrhythmic events in Brugada syndrome is not yet established. The aim of the present study was to examine the usefulness of various markers in predicting life-threatening arrhythmic events in the Brugada syndrome.</AbstractText>Forty-six patients with Brugada-type ECGs were cate... |
1,025 | Hypertension and hypertensive heart disease are associated with increased ostial pulmonary vein diameter. | Atrial fibrillation (AF) is associated with increased ostial pulmonary vein (PV) diameter and commonly with hypertension. We sought to investigate ostial PV anatomy in patients with and without AF with the goal of characterizing the relationship to hypertension and cardiovascular disease.</AbstractText>Ostial PV diamet... |
1,026 | Evolution of our knowledge of sudden death due to commotio cordis. | Commotio cordis refers to circulatory arrest due to a nonpenetrating blow to the chest. First discovered in 1932 in a study using large rabbits, it came to the attention of clinicians who encountered children dying suddenly from a chest blow while engaging in sports activities. This review traces the history of commoti... |
1,027 | Electrical characteristics of low atrial septum pacing compared with right atrial appendage pacing. | The study was designed to compare the electrical characteristics of atrial leads placed in the low atrial septum (LAS) with those placed in the right atrial appendage (RAA) associated with dual chamber pacing.</AbstractText>In 86 patients an active-fixation (St. Jude Medical's Tendril DX model 1388T) atrial lead was po... |
1,028 | Effects of successful cardioversion of persistent atrial fibrillation on right ventricular refractoriness and repolarization. | Changes in ventricular refractoriness and repolarization after successful electrical cardioversion to sinus rhythm in persistent atrial fibrillation (AF) patients were studied.</AbstractText>In 33 AF patients with controlled ventricular response, right ventricular ERP (VERP) at three basic cycle lengths (600, 500, 400 ... |
1,029 | [Complications of myocardial infarction]. | Most acute complications of myocardial infarction do not need emergency imaging, since they often result in death prior to hospital admission: ventricular fibrillation and tachycardia, papillary muscle or septal rupture, fissuration and tamponade. Imaging can play a role at distance of the acute phase (papillary muscle... |
1,030 | [Causes and prognosis of syncope in patients with primary dilated cardiomyopathy]. | The causes of adverse prognosis of patients with primary dilated cardiomyopathy remain controversial. Classically, it is thought that syncope is associated with an increased risk of mortality. The aim of this study was to try and identify the causes and prognostic significance of syncope in patients with primary dilate... |
1,031 | Life-threatening ventricular arrhythmia recognition by nonlinear descriptor. | Ventricular tachycardia (VT) and ventricular fibrillation (VF) are ventricular cardiac arrhythmia that could be catastrophic and life threatening. Correct and timely detection of VT or VF can save lives.</AbstractText>In this paper, a multiscale-based non-linear descriptor, the Hurst index, is proposed to characterize ... |
1,032 | Pretreatment with ACE inhibitors improves acute outcome of electrical cardioversion in patients with persistent atrial fibrillation. | Persistent atrial fibrillation (AF) is difficult to treat. In the absence of class I or III antiarrhythmic drugs sinus rhythm is maintained in only 30% of patients during the first year after electrical cardioversion (ECV). One of the remodeling processes induced by AF is fibrosis, which relates to inducibility and mai... |
1,033 | Chronic nicotine in hearts with healed ventricular myocardial infarction promotes atrial flutter that resembles typical human atrial flutter. | The potential of chronic nicotine exposure for atrial fibrillation (AF) and atrial flutter (AFL) in hearts with and without chronic myocardial infarction (MI) remains poorly explored. MI was created in dogs by permanent occlusion of the left anterior descending coronary artery, and dogs were administered nicotine (5 mg... |
1,034 | Incomplete myocardial rupture after coronary embolism of an isolated single coronary artery. | An 82-year-old female was admitted to the coronary care unit with an anterior wall myocardial infarction and cardiogenic shock. She was in chronic atrial fibrillation without oral anticoagulation. Coronary angiography showed occlusion of the left main coronary artery which originated together with a normal right corona... |
1,035 | Activation recovery time measurements in evaluation of global sequence and dispersion of ventricular repolarization. | Activation recovery time (ART), defined as the time from the earliest ventricular activation time to the end of T wave on unipolar electrograms, has been used as an index of myocardial repolarization time. However, it is unknown whether the ART can be used to estimate the global sequence and dispersion of ventricular r... |
1,036 | QT dispersion failed to estimate the global dispersion of ventricular repolarization measured using monophasic action potential mapping technique in swine and patients. | The aim of this study was to evaluate whether the QT dispersion measured from 12-lead electrocardiogram (ECG) can estimate the global dispersion of ventricular repolarization (DVR) measured using a monophasic action potential (MAP) mapping technique. Monophasic action potentials were recorded from 75 +/- 12 left ventri... |
1,037 | Factors associated with an increased chance of survival among patients suffering from an out-of-hospital cardiac arrest in a national perspective in Sweden. | To describe factors associated with an increased chance of survival among patients suffering from an out-of-hospital cardiac arrest in Sweden.</AbstractText>All patients suffering from an out-of-hospital cardiac arrest, which were not crew witnessed, in Sweden and in whom cardiopulmonary resuscitation (CPR) was attempt... |
1,038 | Role of permanent pacing to prevent atrial fibrillation: science advisory from the American Heart Association Council on Clinical Cardiology (Subcommittee on Electrocardiography and Arrhythmias) and the Quality of Care and Outcomes Research Interdisciplinary Working Group, in collaboration with the Heart Rhythm Society... | This advisory summarizes the current database on pacing modalities and algorithms used to prevent and terminate atrial fibrillation (AF). On the basis of the evidence indicating that ventricular pacing is associated with a higher incidence of AF in patients with sinus node dysfunction, a patient who has a history of AF... |
1,039 | [Myocardial ischemia and paroxysmal cardiac arrhythmia in different severity of bronchial asthma]. | The study was undertaken to define the prevalence and pattern of myocardial ischemia and cardiac arrhythmia in patients with persistent bronchial asthma (BA) in relation to its severity. Eighty-one patients with persistent BA, including 21 patients with mild BA, 39 with moderate BA, and 21 with severe BA, were examined... |
1,040 | Cardiac wall motion abnormalities observed in a patient with transient hyperthyroidism. | A 74-year-old woman, with a history of hypertension and hyperlipidemia, was admitted to our hospital. She was found to have a sinus tachycardia with ST-segment elevations in leads II, III, (a)V(F), and V(3) through V(6) in electrocardiography, hypokinesis of the left ventricular apex by echocardiography, and normal fin... |
1,041 | A case of the toxicity of pilsicainide hydrochloride with comparison of the serial serum pilsicainide levels and electrocardiographic findings. | We treated an 88-year-old man with aortic valvular stenosis/insufficiency and paroxysmal atrial fibrillation, who developed ventricular tachycardia due to pilsicainide toxicity. He was treated at the outpatient clinic of his local hospital, and was administered pilsicainide (100 mg/day) for atrial fibrillation. The ele... |
1,042 | Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association. | Since its introduction as a clinical entity in 1992, the Brugada syndrome has progressed from being a rare disease to one that is second only to automobile accidents as a cause of death among young adults in some countries. Electrocardiographically characterized by a distinct ST-segment elevation in the right precordia... |
1,043 | In vivo and in vitro antiarrhythmic effects of SSR149744C in animal models of atrial fibrillation and ventricular arrhythmias. | SSR149744C (2-butyl-3-{4-[3-(dibutylamino)propyl]benzoyl}-1-benzofuran-5-carboxylate isopropyl fumarate) is a new noniodinated benzofuran derivative structurally related to amiodarone and dronedarone that is currently undergoing clinical trials as an antiarrhythmic agent. As SSR149744C exhibits electrophysiological and... |
1,044 | Changes in demographic factors and mortality after out-of-hospital cardiac arrest in Sweden. | To describe changes between 1992 and 2003 in age, sex, factors at resuscitation and survival among patients suffering from out-of-hospital cardiac arrest in Sweden.</AbstractText>This was a prospective observational study including various ambulance organizations in Sweden. Patients suffering from out-of-hospital cardi... |
1,045 | Tachycardia-induced cardiomyopathy: atrial fibrillation and congestive heart failure. | Tachycardia-induced cardiomyopathy occurs as a result of prolonged, excessive heart rates. Ventricular function may improve significantly upon control of the heart rate. We present a case of a patient with atrial fibrillation with rapid ventricular response who showed a dramatic improvement in left ventricular function... |
1,046 | Rate control vs. pulmonary vein isolation. | Atrial fibrillation (AF) is a frequent arrhythmia encountered in clinical practice. It can be asymptomatic in some patients but incapacitating in others. Regardless of symptoms, patients at increased risk of embolism need chronic anticoagulation. In patients with AF and a rapid ventricular response that cannot be contr... |
1,047 | Ablation therapy of supraventricular tachycardia in elderly persons. | Ablation of supraventricular tachycardia in elderly persons presents a challenging problem to electrophysiologists. Friable cardiac structures, prone to catheter perforation, comorbid cardiovascular disease, and the propensity to develop atrial fibrillation and thromboembolic complications, place these patients at high... |
1,048 | Role of electrophysiologic studies, signal-averaged electrocardiography, heart rate variability, T-wave alternans, and loop recorders for risk stratification of ventricular arrhythmias. | Ventricular tachycardia and fibrillation are major causes of morbidity and mortality after myocardial infarction. Frequently, sudden cardiac death is the first manifestation of such malignant rhythms. Optimal risk stratification strategies in this population are of utmost importance. In this review the authors discuss ... |
1,049 | [Defibrillators--end of sudden cardiac death?]. | The ventricular fibrillation is still the main cause of a sudden cardiac death, even though it was described 155 years ago in experiment (M. Hoffa 1849) and its therapy--defibrillation--has been known since 1947 (C. Beck). In Europe 2500 inhabitants suffer from cardiac arrest daily and 90% is caused by ventricular fibr... |
1,050 | Noninvasive sudden death risk stratification by ambulatory ECG-based T-wave alternans analysis: evidence and methodological guidelines. | Extensive experimental and clinical evidence supports the utility of T-wave alternans (TWA) as a marker of risk for ventricular fibrillation. This entity appears to reflect the fundamental arrhythmogenic property of enhanced dispersion of repolarization. This relationship probably accounts for its relative ubiquity in ... |
1,051 | Heart rate turbulence: a new predictor for risk of sudden cardiac death. | Initial acceleration and a subsequent deceleration of sinus rhythm following a ventricular ectopic beat with a compensatory pause has been termed heart rate turbulence (HRT). The changes in sinus rhythm are thought to be mediated by a baroreflex response to the lower stroke volume of the ectopic beat. HRT is vagally me... |
1,052 | Exercise-induced ventricular arrhythmias and cardiovascular death. | Exercise-induced ventricular arrhythmias (EIVA) are frequently observed during exercise testing. However, the clinical guidelines do not specify their significance and so we examined this issue in our population.</AbstractText>A retrospective analysis of prospectively collected data was performed on 5754 consecutive ma... |
1,053 | Effect of reperfusion on P-wave duration and P-wave dispersion in acute myocardial infarction: primary angioplasty versus thrombolytic therapy. | Atrial fibrillation (AF) is a common arrhythmia occurring in about 10-20% of patients with acute myocardial infarction (AMI). P-wave dispersion (PWd) and P-wave duration (PWD) have been used to evaluate the discontinuous propagation of sinus impulse and the prolongation of atrial conduction time, respectively. This stu... |
1,054 | Assessment of left atrial volumes in sinus rhythm and atrial fibrillation using the biplane area-length method and cardiovascular magnetic resonance imaging with TrueFISP. | To determine whether the biplane area-length method can be used for the evaluation of left atrial volumes and ejection fraction with cardiovascular magnetic resonance imaging (CMR) by TrueFISP in normal subjects and patients with atrial fibrillation.</AbstractText>Atrial fibrillation is the most common arrhythmia in el... |
1,055 | Out-of-hospital cardiac arrest locations in a rural community: where should we place AEDs? | Early defibrillation improves survival for patients suffering cardiac arrest from ventricular fibrillation (VF) or ventricular tachycardia (VT). Automated external defibrillators (AEDs) should be placed in locations in which there is a high incidence of out-of-hospital cardiac arrest (OOHCA). The study objective was to... |
1,056 | ["Highlights" in emergency medicine -- severe head trauma, polytrauma and cardiac arrest]. | According to scientific publications focusing on emergency medicine and published in international journals in the past few months, new and clinically important results can be identified. In patients with severe head trauma (SHT), application of hypertonic solutions is possible; long term outcome, however, is not impro... |
1,057 | Effects of cyclic GMP and its protein kinase on the contraction of ventricular myocytes from hearts after cardiopulmonary arrest. | Hearts undergoing cardiopulmonary arrest and resuscitation have depressed function and may have changes in signal transduction. We hypothesized that the cyclic GMP (cGMP) signaling pathway would be altered in the post-resuscitation heart. This was studied in ventricular myocytes from 7 anesthetized open-chest rabbits. ... |
1,058 | Hepatotoxicity during rapid intravenous loading with amiodarone: Description of three cases and review of the literature. | Atrial fibrillation is the most common arrhythmia after cardiac surgery. Amiodarone can effectively prevent and control postoperative atrial and ventricular fibrillation. Acute hepatic damage after intravenous amiodarone, which can be fatal, is not well recognized. We describe three cases of acute hepatocellular injury... |
1,059 | Vasopressin for cardiac arrest: a systematic review and meta-analysis. | The current guidelines for cardiopulmonary resuscitation recommend vasopressin as an alternative to epinephrine for the treatment of adult shock-refractory ventricular fibrillation. The objective of this study was to determine the effectiveness of vasopressin in the treatment of cardiac arrest.</AbstractText>We perform... |
1,060 | Long-term prognosis of individuals with right precordial ST-segment-elevation Brugada syndrome. | Brugada syndrome is an arrhythmogenic disease characterized by an ECG pattern of ST-segment elevation in the right precordial leads and an increased risk of sudden cardiac death as a result of ventricular fibrillation. Controversy exists with regard to risk stratification and therapeutic management, particularly in asy... |
1,061 | Targeted modification of atrial electrophysiology by homogeneous transmural atrial gene transfer. | Safe and effective myocardial gene transfer remains elusive. Heterogeneous ventricular gene delivery has been achieved in small mammals but generally with methods not readily transferable to the clinic. Atrium-specific gene transfer has not yet been reported. We hypothesized that homogeneous atrial gene transfer could ... |
1,062 | Comparison of the effects of metoclopramide and domperidone on HERG channels. | Torsades de pointes (TdP) is a potentially fatal form of ventricular arrhythmia that occurs under conditions where cardiac repolarization is delayed (as indicated by prolonged QT intervals from electrocardiographic recordings). A likely mechanism for QT prolongation and TdP is blockade of the rapid component of the car... |
1,063 | Prevalence of diastolic dysfunction as a possible cause of dyspnea in the elderly. | Symptoms in patients with heart failure and preserved left ventricular ejection fraction may be caused by isolated diastolic dysfunction. The purpose of this study was to assess the prevalence of diastolic dysfunction as a potential cause of dyspnea in a sample of elderly subjects, as well as of isolated diastolic dysf... |
1,064 | [Predictive value of coagulative molecular markers for thromboembolism in patients with nonvalvular atrial fibrillation: prospective five-year follow-up study]. | Nonvalvular atrial fibrillation is a known risk factor for thromboembolism. This study investigated the use of coagulation markers to predict thromboembolism in nonvalvular atrial fibrillation patients.</AbstractText>One hundred thirty nonvalvular atrial fibrillation patients (104 males, 26 females, mean age 63.7 +/- 1... |
1,065 | [Cardiovascular manifestations of thyrotoxicosis and thyroid dysfunction caused by amiodarone]. | Cardiovascular manifestations of thyrotoxicosis and thyroid dysfunction caused by amiodarone. The cardiovascular symptoms of thyrotoxicosis were described more than two hundred years ago and remained the basis of diagnosis in modern medicine. Myocardium, peripheral circulation and sympathetic nerve system, all affectin... |
1,066 | Doppler tissue analysis of atrial electromechanical coupling in paroxysmal atrial fibrillation. | The aim of this study was to: (1) evaluate atrial electromechanical coupling using M-mode Doppler tissue; and (2) test its clinical impact for detecting atrial abnormalities in paroxysmal atrial fibrillation (AF). Using Doppler tissue, the time intervals from the onset of P wave until the backward motions of the right ... |
1,067 | Noninvasive prediction of complications with anteroseptal acute myocardial infarction by left ventricular Tei index. | Tei index has been proposed as a noninvasive and simple index that enables the evaluation of global left ventricular (LV) function and prediction of patient prognosis. However, its use to predict complications with acute myocardial infarction (AMI) is not fully investigated. Therefore, the purpose of this study was to ... |
1,068 | Anti-HERG activity and the risk of drug-induced arrhythmias and sudden death. | Drug-induced QTc-prolongation, resulting from inhibition of HERG potassium channels may lead to serious ventricular arrhythmias and sudden death. We studied the quantitative anti-HERG activity of pro-arrhythmic drugs as a risk factor for this outcome in day-to-day practice.</AbstractText>All 284,426 case reports of sus... |
1,069 | Predictors of mortality in patients with acute myocardial infarction and cardiogenic shock. | Although cardiogenic shock (CS) is the leading cause of death for acute myocardial infarction (AMI) patients, reliable predictive factors in the acute stage, such as cardiovascular peptides, have not yet been identified.</AbstractText>In 42 consecutive AMI patients with CS on admission, successfully treated by primary ... |
1,070 | Termination of resuscitative efforts for out-of-hospital cardiac arrests. | To determine the rate of termination of resuscitative efforts for out-of-hospital cardiac arrest patients and whether variability exists among different base hospitals providing online medical control (OLMC).</AbstractText>This was an observational one-year study that included all adult patients in the city of Los Ange... |
1,071 | Potential impact of a targeted cardiopulmonary resuscitation program for older adults on survival from private-residence cardiac arrest. | Traditional cardiopulmonary resuscitation (CPR) training programs do not target older adults who are most likely to witness private-residence cardiac arrests and do not reliably result in a bystander who is likely to perform CPR in the event of an arrest. This study was performed to compare targeted CPR training progra... |
1,072 | Cardiac rate normalization in chronic atrial fibrillation: comparison of long-term efficacy of treatment with amiodarone versus AV node ablation and permanent His-bundle pacing. | Chronic atrial fibrillation (AF) is a common arrhythmia with significant morbidity and mortality. AF has been the subject of considerable attention and intensive clinical research in recent years. Current opinion on the management of AF favors the restoration and maintenance of normal ventricular rhythm. This has sever... |
1,073 | Autonomic profile and arrhythmic risk stratification after surgical repair of tetralogy of Fallot. | Severe ventricular arrhythmias represent one of the main causes of mortality after repair of tetralogy of Fallot. Their appearance is primarily caused by the large ventricular scar created by surgical intervention. However, the role of autonomic activity as a modulating factor should be considered. The aim of our study... |
1,074 | Cerebrovascular risk factors and clinical classification of strokes. | Cerebrovascular risk represents a progressive and evolving concept owing to the particular distribution of risk factors in patients with ischemic stroke and in light of the newest stroke subtype classifications that account for pathophysiological, instrumental, and clinical criteria. Age represents the strongest nonmod... |
1,075 | Development of a substrate of atrial fibrillation during chronic atrioventricular block in the goat. | Atrial dilatation is an important risk factor for atrial fibrillation (AF). In the present study, we monitored the electrophysiological changes during progressive atrial dilatation in chronically instrumented goats.</AbstractText>In 8 goats, 2 screw-in leads with piezoelectric crystals were implanted transvenously in t... |
1,076 | Cost-effectiveness of dual-chamber pacing compared with ventricular pacing for sinus node dysfunction. | Compared with single-chamber ventricular pacing, dual-chamber pacing can reduce adverse events and, as a result, improve quality of life in patients paced for sick sinus syndrome. It is not clear, however, how these benefits compare with the increased cost of dual-chamber pacemakers.</AbstractText>We used 4-year data f... |
1,077 | Survival from in-hospital cardiac arrest: the potential impact of infection. | The aim of this study was to examine the relationship between outcome from cardiac arrest and infection status at the time of in-hospital cardiac arrest.</AbstractText>This was a retrospective database review from a single resuscitation service supporting two major hospitals.</AbstractText>Two urban University Hospital... |
1,078 | Characteristics and outcome among children suffering from out of hospital cardiac arrest in Sweden. | To evaluate the characteristics, outcome and prognostic factors among children suffering from out of hospital cardiac arrest in Sweden.</AbstractText>Patients aged below 18 years suffering from out of hospital cardiac arrest which were not crew witnessed and included in the Swedish cardiac arrest registry were included... |
1,079 | A probabilistic neural network as the predictive classifier of out-of-hospital defibrillation outcomes. | Although modern defibrillators are nearly always successful in terminating ventricular fibrillation (VF), multiple defibrillation attempts are usually required to achieve return of spontaneous circulation (ROSC). This is potentially deleterious as cardiopulmonary resuscitation (CPR) must be discontinued during each def... |
1,080 | Intravenous amiodarone bolus for treatment of atrial fibrillation in patients with advanced congestive heart failure or cardiogenic shock. | The clinical course of patients with advanced organic heart disease is often complicated by the occurrence of atrial fibrillation. Slowing the ventricular rate and, if possible, restoration of normal sinus rhythm is crucial but difficult in the state of decreased ventricular function.</AbstractText>We included 78 conse... |
1,081 | Effects of SEA0400, a Na+/Ca2+ exchange inhibitor, on ventricular arrhythmias in the in vivo dogs. | SEA0400 (2-[4-[(2,5-difluorophenyl)methoxy]phenoxy]-5-ethoxyaniline), a novel and selective inhibitor of Na+/Ca2+ exchanger, was investigated for its possible antiarrhythmic effects on arrhythmias of Ca2+ overload induced by coronary ligation/reperfusion and by digitalis in the dog. SEA0400 (1.0 mg/kg) did not change t... |
1,082 | Recurrent cardiac events in patients with idiopathic ventricular fibrillation, excluding patients with the Brugada syndrome. | The recurrence of cardiac events in patients with idiopathic ventricular fibrillation (VF) excluding patients with the Brugada syndrome is unclear since this entity remains present in previous studies.</AbstractText>Since 1992, 18 patients (72% male) with idiopathic VF out of 455 ICD implants were treated with an impla... |
1,083 | Use of automated external defibrillators in cardiac arrest: an evidence-based analysis. | The objectives were to identify the components of a program to deliver early defibrillation that optimizes the effectiveness of automated external defibrillators (AEDs) in out-of-hospital and hospital settings, to determine whether AEDs are cost-effective, and if cost-effectiveness was determined, to advise on how they... |
1,084 | Implantable cardioverter defibrillators. Prophylactic use: an evidence-based analysis.<Pagination><StartPage>1</StartPage><EndPage>74</EndPage><MedlinePgn>1-74</MedlinePgn></Pagination><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">The use of implantable cardiac defibrillators (ICDs) to prevent sudde... | Numerous clinical evidences as well as experimental studies show an increased vulnerability to atrial arrhythmias by acute stretch of the atrial walls. However, the mechanism by which atrial dilatation favours the development of sustained atrial tachyarrhythmias, such as atrial fibrillation (AF), is not fully understoo... |
1,085 | Rectilinear biphasic waveform defibrillation of out-of-hospital cardiac arrest. | The rectilinear biphasic (RLB) waveform has been shown to effectively defibrillate short-duration ventricular fibrillation (VF) at significantly lower energies than a monophasic damped sine (MDS) waveform. This article reports RLB waveform defibrillation effectiveness for patients presenting in VF during out-of-hospita... |
1,086 | Protective effect of taurine against free radicals damage in the rat myocardium. | Free radicals are highly cytotoxic to the heart and are involved in ischemia/reperfusion injury. In this study, we tested the ability of taurine to neutralize the deleterious effects of free radicals generated ex vivo and in vitro. Taurine was added at a concentration of 0.1 mM to the drinking water of experimental rat... |
1,087 | Morphological detection algorithms for the automatic implantable cardioverter/defibrillator (AICD). | To prevent sudden cardiac death of patients who are at risk from long standing tachyarrhythmia the implantable cardioverter defibrillator (ICD) is the first choice therapy. ICDs use a range of electrostimuli up to defibrillation, which is a non synchronous high energy shock, whereas cardioversion is synchronous with th... |
1,088 | Effect of remodelling, stretch and ischaemia on ventricular fibrillation frequency and dynamics in a heart failure model. | The dynamics of ventricular fibrillation (VF) in the presence of heart failure (HF) are different from those in the normal heart. This has been attributed solely to HF-induced electrophysiologic remodelling. We hypothesized that acute stretch and ischaemia, which are normally present during VF, might contribute signifi... |
1,089 | Three-day magnesium administration prevents atrial fibrillation after coronary artery bypass grafting. | The efficacy of magnesium administration in preventing the occurrence of atrial fibrillation after coronary artery bypass grafting surgery remains controversial. Optimal dose and timing of the administration also await clarification. The purpose of this study was to assess the effect of 3-day postoperative infusion of ... |
1,090 | Critical aortic stenosis in early infancy: surgical treatment for residual lesions after balloon dilation. | The optimal management for critical aortic stenosis in early infancy continues to challenge cardiologists and cardiac surgeons. We present a review of our experience with the surgical treatment of residual aortic valve disease after percutaneous balloon dilation for critical aortic stenosis in early infancy.</AbstractT... |
1,091 | Outcomes of patients with acute coronary syndromes and prior percutaneous coronary intervention: a pooled analysis of three randomized clinical trials. | We sought to characterize the outcomes of patients with a prior percutaneous coronary intervention (PCI) who presented with a non-ST-segment elevation acute coronary syndrome (ACS).</AbstractText>We analysed the 30 and 180 day outcomes of 3012 patients with prior PCI and 21 154 patients without prior PCI enrolled in th... |
1,092 | Prognostic risk of atrial fibrillation in acute myocardial infarction complicated by left ventricular dysfunction: the OPTIMAAL experience. | The present study aimed to determine the frequency and the impact on clinical outcome of atrial fibrillation (AF) in patients with acute myocardial infarction (AMI) and left ventricular dysfunction.</AbstractText>In the OPTIMAAL trial, 5477 patients with AMI and signs of left ventricular dysfunction were included. At b... |
1,093 | Prognostic influence of mitral regurgitation prior to a first myocardial infarction. | Mitral regurgitation (MR) following an acute myocardial infarction (AMI) confers an adverse prognosis during long-term follow-up. There are no studies evaluating the influence of pre-AMI MR in the short- and long-term prognosis of such patients. Our aim was to assess the prognostic value of pre-AMI MR in the short- and... |
1,094 | Functional impact of rate irregularity in patients with heart failure and atrial fibrillation receiving cardiac resynchronization therapy. | Atrial fibrillation (AFib) with a rapid ventricular response may adversely impact cardiac performance, especially in patients with heart failure. However, it remains uncertain whether rhythm irregularity per se has unfavourable effects apart from tachycardia, and whether rate regularization alone can improve heart func... |
1,095 | Comparative assessment of right, left, and biventricular pacing in patients with permanent atrial fibrillation. | Left ventricular (LV) and biventricular (BiV) pacing are potentially superior to right ventricular (RV) apical pacing in patients undergoing atrioventricular (AV) junction ablation and pacing for permanent atrial fibrillation.</AbstractText>Prospective randomized, single-blind, 3-month crossover comparison between RV a... |
1,096 | [Effect of tetradrine on electrophysilogic changes caused by rising of left ventricular preload in guinea pigs]. | To investigate the changes of guinea pig heart electrophysiological properties caused by increasing left ventricular preload, and to assess the effects of tetradrine on these changes.</AbstractText>Working model preparation of guinea pig hearts in vitro was used, and the preload of left ventricle was increased by adjus... |
1,097 | [A case of cardiogenic syncope in a drug-addict patient]. | Torsade de pointes is a polymorphic ventricular tachycardia, associated with prolonged QT interval and characterized by twisting of the mean electrical axis of the QRS complexes around an isoelectric line. The long QT syndrome can be divided into two categories, congenital and acquired. The congenital long QT syndrome ... |
1,098 | Induction of ventricular arrhythmias following mechanical impact: a simulation study in 3D. | Commotio cordis, mechanical induction of heart rhythm disturbances, including sudden cardiac death, in the absence of corresponding structural damage, has been reported with increasing frequency in young individuals participating in sporting activities. Recently, the electrophysiological changes during c. cordis have b... |
1,099 | [Subclinical thyroid disease: subclinical hypothyroidism and hyperthyroidism]. | Subclinical hypothyroidism (SHT) and subclinical hyperthyroidism (SCH) are defined as normal serum free T4 and T3 levels associated with elevated (SHT) or subnormal (SCH) serum TSH levels, respectively. Symptoms and signs of thyroid dysfunction are scarce. The prevalence is low. In SHT, total cholesterol and LDL-C are ... |
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