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14,500 | Effects of a novel amiodarone-like compound SAR114646A on the pig atrium and susceptibility to ventricular fibrillation in dogs and pigs. | Amiodarone is one of the most effective antiarrhythmic drugs. However, poor solubility of this compound has limited its intravenous application. SAR11464A is a water-soluble amiodarone-like drug that lacks iodine and inhibits multiple cardiac ion channels in vitro. This study evaluated the antiarrhythmic efficacy of th... |
14,501 | Cardiac aging: from molecular mechanisms to significance in human health and disease. | Cardiovascular diseases (CVDs) are the major causes of death in the western world. The incidence of cardiovascular disease as well as the rate of cardiovascular mortality and morbidity increase exponentially in the elderly population, suggesting that age per se is a major risk factor of CVDs. The physiologic changes of... |
14,502 | Effect of amiodarone on dispersion of ventricular repolarization in a canine congestive heart failure model. | The effects of amiodarone on ventricular electrophysiological parameters, especially the dispersion of ventricular repolarization, were investigated in a canine model of congestive heart failure (CHF). Dogs were randomized to either a control, amiodarone, CHF, or CHF+amiodarone group. Dogs in the CHF and CHF+amiodarone... |
14,503 | Outcomes of mild therapeutic hypothermia after in-hospital cardiac arrest. | Although the benefits of mild therapeutic hypothermia (MTH) in selected patients after out-of-hospital cardiac arrest have been consistently demonstrated, no controlled trial of MTH in selected patients after in-hospital cardiac arrest (IHCA) has been published. We sought to assess the benefit of MTH after IHCA in pati... |
14,504 | Left atrial expansion index for predicting atrial fibrillation and in-hospital mortality after coronary artery bypass graft surgery. | Atrial fibrillation (AF), a common complication after coronary artery bypass graft surgery (CABG), is associated with prolonged hospital stay. This prospective study assessed the accuracy of left atrial parameters and additional preoperative characteristics for predicting post-CABG AF and in-hospital mortality.</Abstra... |
14,505 | Cardiac arrest from postpartum spontaneous coronary artery dissection. | We present the case of a 32-year-old woman who presented to the emergency department with a witnessed cardiac arrest. She was otherwise healthy with no cardiac risk factors and had undergone an uneventful repeated cesarean section 3 days priorly. The patient underwent defibrillation, out of ventricular fibrillation to ... |
14,506 | Shortened Ca2+ signaling refractoriness underlies cellular arrhythmogenesis in a postinfarction model of sudden cardiac death. | Diastolic spontaneous Ca(2+) waves (DCWs) are recognized as important contributors to triggered arrhythmias. DCWs are thought to arise when [Ca(2+)] in sarcoplasmic reticulum ([Ca(2+)](SR)) reaches a certain threshold level, which might be reduced in cardiac disease as a consequence of sensitization of ryanodine recept... |
14,507 | Contact force-controlled zero-fluoroscopy catheter ablation of right-sided and left atrial arrhythmia substrates. | Conventional catheter ablation of cardiac arrhythmias is associated with radiation risks for patients and laboratory personnel. However, nonfluoroscopic catheter guidance may increase the risk for inadvertent cardiac injury. A novel radiofrequency ablation catheter capable of real-time tissue-tip contact force measurem... |
14,508 | Ischemia-modified albumin use as a prognostic factor in coronary bypass surgery. | Various types of markers have been used so far in order to reveal myocardial perfusion defect. However, these markers usually appear in the necrosis phase or in the late stage. Having been the focus of various investigations recently, ischemia-modified albumin (IMA) is helpful in establishing diagnosis in the early sta... |
14,509 | Height and risk of heart failure in the Physicians' Health Study. | Although previous studies have reported an association between height and cardiovascular disease, it is unclear whether height is associated with the risk of heart failure (HF). We hypothesized that height would be inversely associated with HF risk. We used prospective data from 22,042 male physicians (mean age 53.8 ye... |
14,510 | Progressive conduction defects and cardiac death in late infantile neuronal ceroid lipofuscinosis. | This article reports the case of a female with late infantile neuronal ceroid lipofuscinosis who developed right and left anterior bundle branch blocks and episodic bradycardia at 23 years of age. Several episodes of supraventricular tachycardia manifested at 23 and 27 years of age. In addition, a transient second-degr... |
14,511 | Left atrial size predicts the onset of atrial fibrillation after major pulmonary resections. | Atrial fibrillation (AF) is a frequent complication after pulmonary resections. Notwithstanding prevention and early treatment it may show a negative impact on the outcome. We assessed the role of echocardiographic variables to predict the onset of this complication.</AbstractText>One-hundred and thirty-four patients w... |
14,512 | Implantation of additional defibrillation lead into the coronary sinus: an effective method of decreasing defibrillation threshold. | We report a case of successful implantation of an additional defibrillation lead into the coronary sinus due to high defibrillation threshold (DFT) in a seriously ill patient with a history of extensive myocardial infarction referred for implantable cardioverter- defibrillator implantation after an episode of unstable ... |
14,513 | The incidence and prognostic significance of cardiac arrhythmias and conduction abnormalities in patients with acute coronary syndromes and renal dysfunction. | The incidence of cardiac arrhythmias, including atrial fibrillation (AF) in chronic kidney disease, is unknown, although AF is several times more common in patients with end-stage kidney disease than in the general population.</AbstractText>To assess the incidence, types and management of cardiac arrhythmias and conduc... |
14,514 | Altered trans-mitral flow velocity pattern after exercise predicts development of new-onset atrial fibrillation in elderly patients with impaired left ventricular relaxation at rest: prognostic value of diastolic stress echocardiography. | This study attempted to determine whether exercise induced left ventricular (LV) diastolic dysfunction estimated by altered trans-mitral flow (TMF) velocity pattern after exercise is associated with increased risk of cardiac events including new-onset atrial fibrillation (AF) in elderly patients with impaired LV relaxa... |
14,515 | Risk of malignant arrhythmias in initially symptomatic patients with Wolff-Parkinson-White syndrome: results of a prospective long-term electrophysiological follow-up study. | The available amount of detailed long-term data in patients with Wolff-Parkinson-White syndrome is limited, and no prospective electrophysiological studies looking at predictors of malignant arrhythmia are available.</AbstractText>Among 8575 symptomatic Wolff-Parkinson-White patients with atrioventricular reentrant tac... |
14,516 | [Venous thrombosis secondary to catheter insertion for hypothermia after cardiac arrest. Report of one case]. | To improve survival and reduce neurological injury, the use of mild hypothermia following cardiac arrest has been recommended. We report a 65 years old woman who presented an out-of-hospital ventricular fibrillation and cardiac arrest. The patient was comatose following initial resuscitation and was admitted into the I... |
14,517 | Simultaneous Doppler tracing of transmitral inflow and mitral annular velocity as an estimate of elevated left ventricular filling pressure in patients with atrial fibrillation. | The time interval between the onset of early transmitral flow velocity (E) and that of early diastolic mitral annular velocity (e') (T(E-e')) is a good predictor of elevated left ventricular (LV) filling pressure in patients with sinus rhythm. Although the evaluation of LV filling pressure using E/e' has been challengi... |
14,518 | J-wave-associated ventricular fibrillation in a patient with a subarachnoid haemorrhage. | We report a case of 59-year-old man with subarachnoid haemorrhage (SAH) complicated by ventricular fibrillation (VF). Continuous electrocardiogram monitoring revealed that J-waves appeared immediately before the VF. The present report is the first to describe a J-wave-associated VF as another possible mechanism of sudd... |
14,519 | Does appropriate treatment of the primary underlying cause of PEA during resuscitation improve patients' survival? | We aimed to document how often patients received appropriate treatment of the primary cause underlying pulseless electrical activity (PEA) during cardiopulmonary resuscitation (CPR) and how it affected their outcome.</AbstractText>Data were collected between 2003 and 2010 in Finland and Sweden. All adult patients who u... |
14,520 | [Circadian rhythm and time variations in out-hospital sudden cardiac arrest]. | To analyze the chronobiological and time variations of out- hospital cardiac arrest (OHCA).</AbstractText>A retrospective descriptive study was made.</AbstractText>All cases of OHCA of cardiac origin registered over 18 months in the database of the emergency medical service (EMS) of the Autonomous Community of Castilla... |
14,521 | Shock advisory system with minimal delay triggering after end of chest compressions: accuracy and gained hands-off time. | Shortening hands-off intervals can improve benefits from defibrillation. This study presents the performance of a shock advisory system (SAS), which aims to decrease the pre-shock pauses by triggering fast rhythm analysis at minimal delay after end of chest compressions (CC).</AbstractText>The SAS is evaluated on a dat... |
14,522 | Delayed high-quality CPR does not improve outcomes. | The quality of cardiopulmonary resuscitation (CPR) is an important factor in the outcome of cardiac arrest. Our objective was to compare outcomes following either immediate low-quality (LQ) CPR or delayed high-quality (HQ) CPR. We hypothesized that delayed HQ CPR will improve the outcomes of CPR in comparison to immedi... |
14,523 | Sodium nitroprusside enhanced cardiopulmonary resuscitation prevents post-resuscitation left ventricular dysfunction and improves 24-hour survival and neurological function in a porcine model of prolonged untreated ventricular fibrillation. | Sodium nitroprusside-enhanced CPR, or SNPeCPR, consists of active compression-decompression CPR with an impedance threshold device, abdominal compression, and intravenous sodium nitroprusside (SNP). We hypothesize that SNPeCPR will improve post resuscitation left ventricular function and neurological function compared ... |
14,524 | Optimizing the duration of CPR prior to defibrillation improves the outcome of CPR in a rat model of prolonged cardiac arrest. | This study was to investigate whether optimal duration of CPR prior to defibrillation could be guided by Amplitude Spectrum Analysis (AMSA) in the setting of prolonged VF on outcome of CPR.</AbstractText>VF was induced in thirty Sprague-Dawley rats and untreated for 8 minutes. Animals were then randomized into 3 groups... |
14,525 | Prevalence and hemodynamic effects of leaning during CPR. | Cardiopulmonary resuscitation (CPR) guidelines recommend complete release between chest compressions (CC).</AbstractText>Evaluate the hemodynamic effects of leaning (incomplete chest wall release) during CPR and the prevalence of leaning during CPR.</AbstractText>In piglet ventricular fibrillation cardiac arrests, 10% ... |
14,526 | The role of the renin-angiotensin system blocking in the management of atrial fibrillation. | To review current available evidence for the role of renin-angiotensin system blockade in the management of atrial fibrillation.</AbstractText>We conducted a PubMed and Medline literature search (January 1980 through July 2011) to identify all clinical trials published in English concerning the use of angiotensin conve... |
14,527 | Function of the CaMKII-ryanodine receptor signaling pathway in rabbits with left ventricular hypertrophy and triggered ventricular arrhythmia. | Calcium calmodulin-dependent kinase II (CaMKII) can be more active in patients with left ventricular hypertrophy (LVH), which in turn causes phosphorylation of ryanodine receptors, resulting in inactivation and the instability of intracellular calcium homeostasis. The present study aimed to determine the effect of CaMK... |
14,528 | Effect of hypertransfusion on the gastrointestinal tract after cardiac arrest in a porcine model. | This study aimed to determine the potential protective effect of inducing hypertransfusion to the gastrointestinal tract following a porcine model of cardiac arrest and cardiopulmonary resuscitation (CPR) by evaluating the influence of gastrointestinal ultrastructure, ATPase and serum diamine oxidase.</AbstractText>Ven... |
14,529 | Biventricular noncompaction cardiomyopathy in a patient presenting with new onset seizure: case report. | Ventricular noncompaction (VNC) of the myocardium is a rare genetic cardiomyopathy caused by a disorder during endocardial morphogenesis and could be accompanied by life-threatening complications. The major clinical manifestations of VNC are heart failure, arrhythmias, and embolic events. The left ventricle is the most... |
14,530 | A comparison of verapamil and digoxin for heart rate control in atrial fibrillation. | Atrial fibrillation (AF) is one of the most common types of sustained dysrhythmia and there are some disagreements about its treatment. The goals of AF treatment include the control of ventricular rate, the establishment of sinus rhythm and the prevention of thromboembolic events. In this study, the effect of verapamil... |
14,531 | Zero flow global ischemia-induced injuries in rat heart are attenuated by natural honey. | In the present study, effects of preischemic administration of natural honey on cardiac arrhythmias and myocardial infarction size during zero flow global ischemia were investigated in isolated rat heart.</AbstractText>The isolated hearts were subjected to 30 min zero flow global ischemia followed by 120 min reperfusio... |
14,532 | Stroke prevention in atrial fibrillation: latest clinical trials and guidelines. | Atrial Fibrillation (AF) is the most common sustained arrhythmia and 1/6 strokes is attributed to AF. The cornerstone of treatment remains maintaining sinus rhythm or appropriate ventricular rate control in addition to prevention of stroke. Oral anticoagulation therapy (OAC) with vitamin K antagonists (VKAs) has been t... |
14,533 | Contrast media injection into right coronary artery caused thrombus extraction to aorta that may have resulted in left main trunk thrombosis. | A 59-year-old man with inferior acute myocardial infarction underwent an urgent coronary angiography and as a result a total occlusion of the ostial right coronary artery (RCA) was observed. Interestingly, the thrombus in the RCA clearly shortened within 2.3 s during the contrast media injection. While we prepared for ... |
14,534 | To cool or not to cool during cardiopulmonary resuscitation. | Therapeutic hypothermia following cardiac arrest improves neurologic outcome following adult ventricular fibrillation (VF) cardiac arrest and perinatal hypoxic ischemic encephalopathy. Evaluation of therapeutic hypothermia in the pediatric cardiac arrest population has been limited thus far to retrospective evaluations... |
14,535 | Coronary air embolism during removal of a central venous catheter. | Acute air embolism has been described during central venous cannulation, but it may also occur during catheter removal in a spontaneously breathing patient. We describe an episode of acute coronary ischaemia that occurred during CV catheter removal.</AbstractText>A 23-year-old male, multiple trauma patient was treated ... |
14,536 | [Sudden cardiac arrest in ventricular fibrillation mechanism as a first manifestation of primary mitral valve prolapse]. | We present the case of a 58 year-old patient with a primary mitral valve prolapse (MVP) at whose first manifestation of the disease was a sudden cardiac death (SCD) in ventricular fibrillation mechanism. In ECG paroxysmal atrial fibrillation was detected. The arrhythmia became persistent atrial fibrillation but in ECG ... |
14,537 | [Influence of increased mean heart rate at rest on mortality and ventricular tachycardia resulting in adequate intervention in patients after implantable cardioverter-defibrillator implantation]. | Increased heart rate at rest (HR) is a risk factor of sudden cardiac death (SCD) and cardiovascular mortality.</AbstractText>Retrospective assessment of increased HR influence on mortality and ventricular tachycardia followed by adequate ICD intervention.</AbstractText>350 patients (52 female, 298 male), mean age 65.1+... |
14,538 | Diagnostic utility of specific electrocardiographical parameters in predicting left ventricular function. | Changes in electrocardiography (ECG) parameters, including sinus tachycardia, atrial fibrillation, bundle branch blocks, Q waves and left ventricular (LV) hypertrophy, are commonly observed in patients with heart failure (HF).</AbstractText>To determine whether specific ECG parameters have a diagnostic role in predicti... |
14,539 | Pulmonary embolism caused by delayed heparin-induced thrombocytopenia in a patient who received prophylactic LMWH. | Heparin induced thrombocytopenia (HIT) is a serious complication associated with heparin use. HIT usually develops between 5-14 days after starting heparin. Delayed-onset HIT can still occur 9-45 days after heparin had been discontinued. In patients with delayed HIT, the patient might be admitted to the hospital for ne... |
14,540 | Fatal septicemia and endotoxic shock due to Aeromonas hydrophila. | Although rare, bloodstream infections caused by Aeromonas tend to be very severe and progress rapidly.</AbstractText>We report a case of an 81-year-old man with fetal septicemia and endotoxin shock caused by Aeromonas hydrophila. The patient had dilated cardiomyopathy, paroxysmal atrial fibrillation, interstitial pneum... |
14,541 | Atrial Fibrillation with Rapid Ventricular Response following use of Dietary Supplement Containing 1,3 Dimethylamylamine and Caffeine. | Our nation?s servicemembers commonly use dietary supplements to enhance their performance. Despite this prolific use, many of these products have detrimental side-effects that compromise servicemembers? health and could, by proxy, compromise a mission. This paper presents the case of a 32-year old Navy Special Operatio... |
14,542 | [Microcirculatory parameters in patients with myocardial infarction]. | To estimate the prognostic value of the parameters of the microcirculatory bed for the assessment of risk for in-hospital death and cardiovascular events in patients with myocardial infarction (MI).</AbstractText>Thirty (62.5%) and 18 (37.5%) of 48 patients (mean age 63.5 +/- 10.2 years) admitted to an intensive care u... |
14,543 | Importance and inter-relationship of tissue Doppler variables for predicting adverse outcomes in high-risk patients: an analysis of 388 diabetic patients referred for coronary angiography. | To investigate the relative importance of individual tissue Doppler imaging variables to predict adverse events in a high-risk population with diabetes, ischaemic heart disease, and/or systolic dysfunction.</AbstractText>Transthoracic echocardiograms were analysed in 388 diabetic patients without significant valve dise... |
14,544 | Amiodarone-induced T-U fusion. | Amiodarone is a widely used antiarrythmic drug for various atrial and ventricular arrhythmias. It has the potential to cause prolongation of the QT interval, which, in turn, can increases the incidence of torsade de pointes. Amiodarone is also one of the causes of prominent U waves. The presented case exemplifies the p... |
14,545 | Cerebrospinal fluid biochemistry reflects effects of therapeutic hypothermia after cardiac arrest in a porcine model. | Mild induced hypothermia (MIH) is recommended to treat neurologic injury after cardiac arrest (CA). However, clinical trials to assess MIH benefit after CA have been largely inconclusive. We investigated the subsequent changes in cerebrospinal fluid (CSF) biochemistry after MIH (33°C-34°C for 12 hours) and ev... |
14,546 | Continuous chest compressions improve survival and neurologic outcome in a swine model of prolonged ventricular fibrillation. | Evidence suggests that any interruptions, including those of rescue breaths, during cardiopulmonary resuscitation (CPR) have significant, detrimental effects on survival. The 2010 International Liaison Committee on Resuscitation guidelines strongly emphasized on the importance of minimizing interruptions during chest c... |
14,547 | Novel association patterns of cardiac remodeling markers in patients with essential hypertension and atrial fibrillation. | Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are essential for the cardiac extracellular matrix (ECM) remodeling. We investigated differences in serum levels of these markers between patients with atrial fibrillation (AF) and sinus rhythm (SR).</AbstractText>Serum levels of MMP-2, MMP-3, MMP-9 a... |
14,548 | What is the role of chest compression depth during out-of-hospital cardiac arrest resuscitation? | The 2010 international guidelines for cardiopulmonary resuscitation recently recommended an increase in the minimum compression depth from 38 to 50 mm, although there are limited human data to support this. We sought to study patterns of cardiopulmonary resuscitation compression depth and their associations with patien... |
14,549 | Treating cardiac arrhythmias detected with an implantable cardiac monitor in patients after an acute myocardial infarction. | Using an implantable cardiac monitor (ICM) in patients with acute myocardial infarction (MI) allows continuous electrocardiogram monitoring and provides a much more detailed picture of the incidence of brady- and tachyarrhythmias than conventional follow-up. The CARISMA study was the first to use the ICM in post-MI pat... |
14,550 | Early mineralocorticoid receptor blockade in primary percutaneous coronary intervention for ST-elevation myocardial infarction is associated with a reduction of life-threatening ventricular arrhythmia. | Aldosterone levels are high early after admission for ST elevation myocardial infarction (STEMI) concomitantly with high risk of sudden death and life-threatening ventricular arrhythmia.</AbstractText>We assessed the hypothesis that early aldosterone blockade on admission for primary percutaneous coronary intervention ... |
14,551 | Heterogeneity of left ventricular signal characteristics in response to acute vagal stimulation during ventricular fibrillation in dogs. | Studies have shown that long-term vagal stimulation is protective against ventricular fibrillation; however, the effects of acute vagal stimulation during ventricular fibrillation in the normal heart have not been investigated. We examined the effects of acute vagal stimulation on ventricular fibrillation in a canine m... |
14,552 | Spontaneous ventricular fibrillation in right ventricular failure secondary to chronic pulmonary hypertension. | Right ventricular failure (RVF) in pulmonary hypertension (PH) is associated with increased incidence of sudden death by a poorly explored mechanism. We test the hypothesis that PH promotes spontaneous ventricular fibrillation (VF) during a critical post-PH onset period characterized by a sudden increase in mortality.<... |
14,553 | Comparison of Microlife BP A200 Plus and Omron M6 blood pressure monitors to detect atrial fibrillation in hypertensive patients. | Self-monitoring home blood pressure (BP) devices are currently recommended for long-term follow-up of hypertension and its management. Some of these devices are integrated with algorithms aimed at detecting atrial fibrillation (AF), which is common essential hypertension. This study was designed to compare the diagnost... |
14,554 | Comparison of defibrillation efficacy between two pads placements in a pediatric porcine model of cardiac arrest. | The placement of defibrillation pads at ideal anatomical sites is one of the major determinants of transthoracic defibrillation success. However, the optimal pads position for ventricular defibrillation is still undetermined. In the present study, we compared the effects of two different pads positions on defibrillatio... |
14,555 | Characteristics and outcomes of peripartum versus nonperipartum cardiomyopathy in women using a wearable cardiac defibrillator. | Peripartum cardiomyopathy (PPCM) mortality rates vary between 2% and 56%, with half occurring ≤12 weeks'; postpartum. Although risk factors for PPCM have been identified, predicting sudden cardiac death among PPCM patients remains difficult. This study describes the characteristics and outcomes of PPCM patients ... |
14,556 | Prognostic significance of postprocedural sustained ventricular tachycardia or fibrillation in patients undergoing primary percutaneous coronary intervention (from the HORIZONS-AMI Trial). | The prognostic significance of postprocedure sustained ventricular tachycardia or ventricular fibrillation (VT/VF) in patients undergoing primary percutaneous coronary intervention (PPCI) for ST-segment elevation myocardial infarction (STEMI) has rarely been studied, although a previous study has suggested that its occ... |
14,557 | Outcomes of patients treated with triple antithrombotic therapy after primary percutaneous coronary intervention for ST-elevation myocardial infarction (from the Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction [HORIZONS-AMI] trial). | In the setting of ST-segment elevation myocardial infarction (STEMI), patients at high risk of systemic emboli who undergo primary percutaneous coronary intervention (PCI) using stents might require triple antithrombotic therapy (a combination of aspirin, thienopyridine, and vitamin K antagonist [VKA]). The risks and b... |
14,558 | Early cardiac arrest in patients hospitalized with pneumonia: a report from the American Heart Association's Get With The Guidelines-Resuscitation Program. | Pneumonia is the leading infectious cause of death. Early deterioration and death commonly result from progressive sepsis, shock, respiratory failure, and cardiac complications. Recent data suggest that cardiac arrest may also be common, yet few previous studies have addressed this. Accordingly, we sought to characteri... |
14,559 | Medical treatment of atrial fibrillation. | Atrial fibrillation is an increasingly common arrhythmia which is associated with a substantial burden of cardiovascular disease. The arrhythmia is mostly treated with pharmacological therapy, although some interventional techniques such as left atrial ablation, atrioventricular nodal ablation plus pacemaker implantati... |
14,560 | A common β1-adrenergic receptor polymorphism predicts favorable response to rate-control therapy in atrial fibrillation. | In this study, we evaluated the impact of 2 common β1-adrenergic receptor (β1-AR) polymorphisms (G389R and S49G) in response to ventricular rate control therapy in patients with atrial fibrillation (AF).</AbstractText>Randomized studies have shown that ventricular rate control is an acceptable treatment str... |
14,561 | Risk stratification in Brugada syndrome: results of the PRELUDE (PRogrammed ELectrical stimUlation preDictive valuE) registry. | The PRELUDE (PRogrammed ELectrical stimUlation preDictive valuE) prospective registry was designed to assess the predictive accuracy of sustained ventricular tachycardia/ventricular fibrillation (VTs/VF) inducibility and to identify additional predictors of arrhythmic events in Brugada syndrome patients without history... |
14,562 | Changes in renal function after implantation of continuous-flow left ventricular assist devices. | The aim of this study was to determine renal outcomes after left ventricular assist device (LVAD) implantation.</AbstractText>Renal dysfunction before LVAD placement is frequent, and it is unclear whether it is due to primary renal disease or to poor perfusion.</AbstractText>A retrospective single-center analysis was c... |
14,563 | [Effects of metoprolol on electrophysiology of ischemic and anoxic myocardium in diabetic rats]. | To investigate the effects of metoprolol on electrophysiology of ischemic and anoxic myocardium in diabetic rats.</AbstractText>Forty Sprague-Dawley (SD) rats were divided into 4 groups: diabetes group; diabetes and ablation of left sympathetic nerve group; diabetes and metoprolol group and sham group. The diabetes mod... |
14,564 | Successful surgical repair of a giant calcified left ventricular aneurysm: a report of a case. | A 68-year-old man presented at the outpatient clinic with epigastric discomfort. He had suffered a myocardial infarction 10 years previously. Chest radiography and computed tomography showed a giant calcified aneurysm in the left ventricle. Electrocardiography indicated atrial fibrillation. Echocardiography showed mode... |
14,565 | [Intermittent short QT interval in a patient with sudden cardiac death]. | This paper presents a 21 years-old-male without structural heart disease who was reanimated from a sudden cardiac death event. His familial history included two siblings suddenly dead in their first year of life. The patient had 10 episodes of ventricular tachycardia (some of them were registered). Electrocardiographic... |
14,566 | Visual three-dimensional representation of beat-to-beat electrocardiogram traces during hemodiafiltration. | This study evaluated the usefulness of the three-dimensional representation of electrocardiogram traces (3DECG) to reveal acute and gradual changes during a full session of hemodiafiltration (HDF) in end-stage renal disease (ESRD) patients. Fifteen ESRD patients were included (six men, nine women, age 46 ±&... |
14,567 | Analysis of left ventricular impedance in comparison with ultrasound images. | Cardiac monitoring of ventricular assist devices (VADs) is important for detecting heart failure risks, such as critical arrhythmia and ventricular fibrillation, and for supplying data that are useful for hemodynamic control. Specifically, impedance cardiograms (ICGs) are especially beneficial because they have no effe... |
14,568 | Fatal undersensing of ventricular fibrillation due to intermittent high-amplitude R waves. | A 48-year-old man was admitted after an episode of aborted sudden death with external defibrillation. An implantable cardioverter defibrillator implanted 2 years before for secondary prevention failed to sense properly an episode of ventricular fibrillation. Interrogation of the device showed large oscillatory changes ... |
14,569 | [Mitral valve replacement for heart failure due to hypertrophic obstructive cardiomyopathy; report of a case]. | Myotomy or myectomy are well known as the standard treatment of hypertrophic obstructive cardiomyopathy (HOCM), and mitral valve replacement (MVR) is reported to achieve the equivalent therapeutic effect. And recently, combined treatment with artificial chordae replacement and MVR has been reported to improve the progn... |
14,570 | Myocardial perfusion abnormality in the area of ventricular septum-free wall junction and cardiovascular events in nonobstructive hypertrophic cardiomyopathy. | Myocardial perfusion abnormality in the left ventricle is known to be prognostic in patients with hypertrophic cardiomyopathy (HCM). Magnetic resonance imaging and necropsy studies on HCM hearts revealed myocardial lesions predominating in the area of ventricular septum-free wall junction. We assessed perfusion abnorma... |
14,571 | [Direct current cardioversion in Abidjan: report of a ten-year practice in Institute of Cardiology of Abidjan, Ivory Coast]. | Direct current cardioversion is effective in arrhythmias' termination. Few is known about its use in our practice. This work aims to report its outcomes over a ten-year period in Abidjan.</AbstractText>One thousand, three hundred and ninety one charts of arrhythmic patients were reviewed.</AbstractText>Cardioversion wa... |
14,572 | Risk factors for persistent atrial fibrillation following successful hyperthyroidism treatment with radioiodine therapy. | To investigate the predicting factors for persistent atrial fibrillation (AF) following radioiodine therapy for hyperthyroidism.</AbstractText>Standard 12-lead ECG and 24-h Holter monitoring were performed in 94 patients (38 males, mean age 46.1±8.2 years) with persistent AF following radioiodine therapy for hyper... |
14,573 | Relationship of fragmented QRS with prognostic markers and in-hospital MACE in patients undergoing CABG. | Fragmented QRS complex (fQRS) is associated with increased morbidity and mortality, sudden cardiac death and recurrent cardiovascular events. However, its prognostic role has not been studied comprehensively in patients undergoing coronary artery bypass graft (CABG) surgery. In this study, we investigated the relations... |
14,574 | Evaluation of coronary blood flow velocity during cardiac arrest with circulation maintained through mechanical chest compressions in a porcine model. | Mechanical chest compressions (CCs) have been shown capable of maintaining circulation in humans suffering cardiac arrest for extensive periods of time. Reports have documented a visually normalized coronary blood flow during angiography in such cases (TIMI III flow), but it has never been actually measured. Only indir... |
14,575 | Renin-Angiotensin System and AtrialFibrillation:Understanding the Connection. | Atrial fibrillation (AF) arises as a result of a complex interaction of triggers, perpetuators and the substrate. The recurrence of AF may be partially related to a biologic phenomenon known as remodeling, in which the electrical, mechanical, and structural properties of the atrial tissue and cardiac cells are progress... |
14,576 | Evolution of activation patterns during long-duration ventricular fibrillation in pigs. | Quantitative analysis has demonstrated five temporal stages of activation during the first 10 min of ventricular fibrillation (VF) in dogs. To determine whether these stages exist in another species, we applied the same analysis to the first 10 min of VF recorded in vivo from two 504-electrode arrays, one each on left ... |
14,577 | Safety and efficacy of the remote magnetic navigation for ablation of ventricular tachycardias--a systematic review. | Remote magnetic navigation (RMN) is considered to be a solution for mapping and ablation of several arrhythmias. In this systematic review we aimed to assess the safety and efficacy of RMN in ablation of ventricular tachycardia (VT).</AbstractText>The National Library of Medicine's PubMed database was searched for arti... |
14,578 | TASK-1 channels may modulate action potential duration of human atrial cardiomyocytes. | <AbstractText Label="BACKGROUND/AIMS" NlmCategory="OBJECTIVE">Atrial fibrillation is the most common arrhythmia in the elderly, and potassium channels with atrium-specific expression have been discussed as targets to treat atrial fibrillation. Our aim was to characterize TASK-1 channels in human heart and to functional... |
14,579 | Immediate coronary angiogram in comatose survivors of out-of-hospital cardiac arrest--an Australian study. | The role of immediate coronary angiography and percutaneous coronary intervention (angio±PCI), amongst comatose survivors of out-of-hospital cardiac arrest is unclear. This study was undertaken to evaluate if immediate angio±PCI compared to no initial intervention improves neurological outcome at hospital dis... |
14,580 | Modifications in ventricular fibrillation and capture capacity induced by a linear radiofrequency lesion. | An analysis was made of the effects of a radiofrequency-induced linear lesion during ventricular fibrillation and the capacity to capture myocardium through high-frequency pacing.</AbstractText>Using multiple epicardial electrodes, ventricular fibrillation was recorded in 22 isolated perfused rabbit hearts, analyzing t... |
14,581 | Impact of periprocedural atrial fibrillation on short-term clinical outcomes following percutaneous coronary intervention. | There are few data on the incidence and clinical outcomes of patients with atrial fibrillation (AF) treated in the era of percutaneous coronary intervention (PCI). We analyzed 30-day clinical outcomes in 3,307 consecutive patients with and without AF (sinus rhythm) undergoing PCI from January 2007 through December 2008... |
14,582 | Effect of chest compressions on ventricular activation. | External mechanical forces can cause ventricular capture and fibrillation (i.e., commotio cordis). In animals, we showed that chest compressions (CCs) can also cause the phenomenon. The aim of the present study was to determine whether ventricular capture by CCs occurs in humans. Electronic rhythm strips were analyzed ... |
14,583 | Focal initiation of sustained and nonsustained ventricular tachycardia in a canine model of ischemic cardiomyopathy. | To define the role of focal and reentrant mechanisms underlying nonsustained (NSVT) and sustained ventricular tachycardia (SuVT) induced by programmed stimulation, 3-dimensional cardiac mapping was performed in 8 dogs with heart failure (HF) created by multiple intracoronary microsphere embolizations.</AbstractText>Con... |
14,584 | Watchful waiting for severe mitral regurgitation. | Watchful waiting is an established treatment strategy for asymptomatic patients with severe organic mitral regurgitation. It is based on indications for surgery that are based on current European Society of Cardiology and American Heart Association/American College of Cardiology guideline recommendations, which are def... |
14,585 | Early post-cardiac surgery delirium risk factors. | The purpose of this study was to identify the post-cardiac surgery delirium risk factors and to evaluate clinical outcomes. Data on 90 patients with postoperative delirium after cardiac surgery on cardiopulmonary bypass (CPB) were analyzed retrospectively. The patients were divided into two groups by evaluating the sev... |
14,586 | The management of patients with atrial fibrillation and dronedarone's place in therapy. | The pharmacologic management of atrial fibrillation (AF) includes rate and rhythm control strategies. Antiarrhythmic agents (eg, amiodarone, flecainide, and propafenone) are limited by serious toxicities (including proarrhythmic effects and pulmonary toxicity), which may lead to a reduced net clinical efficacy of rhyth... |
14,587 | A novel variant in plakophilin-2 gene detected in a family with arrhythmogenic right ventricular cardiomyopathy. | Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by fibrofatty replacement of muscular fibers predominantly in the right ventricle and with ventricular arrhythmias as the main clinical manifestation. Mutations in several components of the desmosome genes have been identified and mutations of the ... |
14,588 | Actual situation regarding cardiac etiology determined by clinical diagnosis of and medical examiner's postmortem findings on witnessed out-of-hospital cardiac arrest cases. | To examine indicators that may assist in the diagnosis of cardiac etiology using simple tests in witnessed cardiac etiology out-of-hospital cardiac arrest cases, which is emphasized in the Utstein Style.</AbstractText>The subjects were 165 witnessed cardiac etiology out-of-hospital cardiac arrest cases, which were tran... |
14,589 | Efficacy and safety of vernakalant in recent-onset atrial fibrillation after the European medicines agency approval: systematic review and meta-analysis. | Vernakalant is an emergent antiarrhythmic drug that, in preclinical studies, has demonstrated high efficacy in restoring sinus rhythm and safety in patients with rapid recent-onset atrial fibrillation. The aim of this work was to evaluate the efficacy and safety of vernakalant for cardioversion of recent-onset atrial f... |
14,590 | Pulmonary venous evaluation using electrocardiogram-gated 64-detector row cardiac CT. | Radiofrequency ablation of the pulmonary veins is an accepted treatment for atrial fibrillation. An accurate knowledge of pulmonary venous anatomy and dimensions is desirable prior to such a procedure. The objective of this study was to use 64-detector row cardiac CT to investigate the changes in pulmonary venous dimen... |
14,591 | Did you know? Why amiodarone requires diligent monitoring? | Amiodarone remains one of the most commonly prescribed antiarrhythmics effectively treating atrial fibrillation and ventricular arrhythmias. Diligent monitoring for potentially serious side effects especially in the elderly is paramount. |
14,592 | Current evidence in therapeutic hypothermia for postcardiac arrest care. | The ring of the red notification phone breaks the relative calm of an otherwise typical Monday morning and heralds the arrival of a critically ill patient. The dispatcher announces that EMS is on the way with a 57-year-old man in cardiac arrest, with an ETA of 3 minutes. Shortly after preparations for their arrival are... |
14,593 | Sudden cardiac arrest: associated with anomalous origin of the right coronary artery from the left main coronary artery. | Anomalous origin of the coronary artery from the opposite sinus of Valsalva and a course of that artery between the ascending aorta and the pulmonary artery is a rare congenital anomaly. It can cause myocardial ischemia, syncope, and sudden cardiac death in young people. Herein, we report the case of a 24-year-old man ... |
14,594 | [Autonomic dysfunction and cardiac arrhythmia in patients with obstructive and central sleep apnea]. | Obstructive sleep apnea and central sleep apnea with Cheyne-Stokes respiration are associated with an increased risk of cardiac arrhythmia. Apnea- associated arrhythmia may contribute to sudden cardiac death and premature mortality in those patients. Both forms of sleep apnea excert strong modulatory effects on the aut... |
14,595 | Impact of chronic atrial fibrillation in patients with severe heart failure and indication for CRT: data of two registries with 711 patients (1999-2006 and 2007-6/2008). | Atrial fibrillation (AF) is a relevant comorbidity in heart failure (HF) patients. In milestone cardiac resynchronization therapy (CRT) studies, patients with AF were excluded. We sought to investigate the influence of chronic atrial fibrillation (AF) on patients with CRT. AV node (AVN) ablation is frequently recommend... |
14,596 | Is the coexistence of sustained ST-segment elevation and abnormal Q waves a risk factor for electrical storm in implanted cardioverter defibrillator patients with structural heart diseases? | The aim of this study was to determine whether or not the coexistence of sustained ST-segment elevation and abnormal Q waves (STe-Q) could be a risk factor for electrical storm (ES) in implanted cardioverter defibrillator (ICD) patients with structural heart diseases.</AbstractText>In all, 156 consecutive patients rece... |
14,597 | Validating the acute heart failure index for patients presenting to the emergency department with decompensated heart failure. | The acute heart failure index (AHFI) is a previously derived prediction rule to identify patients presenting to emergency departments (ED) with decompensated heart failure (DHF) at low risk of early life-threatening events.</AbstractText>To validate the AHFI prospectively.</AbstractText>Using a prospective cohort study... |
14,598 | Cardiac arrest and the 2010 advanced cardiac life support guidelines--part IV. | The chance of a successful outcome with any cardiac arrest is prompt initiation of hands-only compression at a rate of at least 100 per min, to a depth of 2 in.,with full chest recoil, and no more than a 10-s interruption of compressions. The priority, regardless of being in a private clinic or in a facility using a te... |
14,599 | Investigating the role of the coronary vasculature in the mechanisms of defibrillation. | The direct role of coronary vessels in defibrillation, although hypothesized to be important, remains to be elucidated. We investigated how vessel-induced virtual electrode polarizations assist reentry termination.</AbstractText>A highly anatomically detailed rabbit ventricular slice bidomain computer model was constru... |
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