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14,400
Implantable cardioverter defibrillator lead placement in the middle cardiac vein after tricuspid valve surgery.
Pacing and defibrillation with an implantable cardioverter defibrillator (ICD) after tricuspid valve surgery can be challenging if right ventricular (RV) lead placement is contraindicated or safe lead placement in the RV apex is impossible.</AbstractText>In six patients for whom RV lead placement and repeat thoracotomy...
14,401
The clinical significance of ventricular arrhythmias during an exercise test in non-competitive and competitive athletes.
Sudden death in athletes can occur during sport activities and is presumably related to ventricular arrhythmias. There are no guidelines concerning athletes who develop ventricular arrhythmias during an exercise test. It is unclear whether they should be allowed to continue with their competitive activity or not.</Abst...
14,402
Chronic oral amiodarone but not dronedarone therapy increases ventricular defibrillation threshold during acute myocardial ischemia in a closed-chest animal model.
Dronedarone, a recently approved antiarrhythmic drug, has been shown to have fewer side effects than amiodarone, particularly with regard to thyroid and neurologic events. Since the effects of either drug on ventricular defibrillation threshold during ischemia are unknown, the aim of this study was to compare the effec...
14,403
Myocardial protection in beating heart cardiac surgery: I: pre- or postconditioning with inhibition of es-ENT1 nucleoside transporter and adenosine deaminase attenuates post-MI reperfusion-mediated ventricular fibrillation and regional contractile dysfunction.
To determine the role of the p-nitrobenzylthioinosine-sensitive equilibrative nucleoside transporter 1 (es-ENT1) in postmyocardial infarction reperfusion injury-mediated ventricular fibrillation and regional dysfunction. We used erythro-9 (2-hydroxy-3-nonyl)-adenine and p-nitrobenzylthioinosine to inhibit both adenosin...
14,404
Association between family risk of stroke and myocardial infarction with prevalent risk factors and coexisting diseases.
Familial transmission of stroke and myocardial infarction (MI) is partially mediated by transmission of cerebrovascular and cardiovascular risk factors. We examined relationships between family risk of stroke and MI with risk factors for these phenotypes.</AbstractText>A cross-sectional association between the stratifi...
14,405
[Management of severe accidental hypothermia].
Accidental hypothermia is an environmental condition with basic principles of classification and resuscitation that apply to mountain, sea or urban scenarios. Along with coagulopathy and acidosis, hypothermia belongs to the lethal triad of trauma victims requiring critical care. A customized healthcare chain is involve...
14,406
Mitral valve repair for severe mitral regurgitation secondary to lone atrial fibrillation.
Significant mitral regurgitation (MR) may arise from isolated annular dilatation secondary to lone atrial fibrillation (AF) and associated atrial remodelling. The aim of the present study is to assess the outcome of surgery for this condition.</AbstractText>Between November 2007 and July 2011, 20 patients underwent mit...
14,407
Therapeutic potential of marine n-3 fatty acids in CABG patients.
Dietary intake of marine n-3 polyunsaturated fatty acids (PUFA) has beneficial effects in various cardiac disorders. Few studies have, however, investigated the therapeutic potential of n-3 PUFA in patients undergoing coronary artery bypass grafting (CABG). Five heterogeneous randomized studies on n-3 PUFA for preventi...
14,408
[C-reactive protein and non-valvula atrial fibrillation combining with thrombosis].
To investigate the alteration of plasma C-reactive protein(CRP) count in patients with non-valvula atrial fibrillation combining thrombosis.</AbstractText>A total of 154 patients with non-valvula atrial fibrillation were divided into thrombus group (n = 46) and non-thrombus group (n = 108) in accordance with transesoph...
14,409
Relationship between left atrial volume and atrial fibrillation following coronary artery bypass grafting.
Atrial fibrillation (AF) is a common complication of coronary artery bypass grafting (CABG). However, limited information is available about the role of preoperative echocardiographic left atrial evaluation to predict AF occurrence after CABG. Thus, we prospectively compared the ability of echocardiographic measurement...
14,410
Methylphenidate and risk of serious cardiovascular events in adults.
The authors sought to determine whether use of methylphenidate in adults is associated with elevated rates of serious cardiovascular events compared with rates in nonusers.</AbstractText>This was a cohort study of new users of methylphenidate based on administrative data from a five-state Medicaid database and a 14-sta...
14,411
Ultra-short course of low-dose amiodarone-induced post-operative fatal pulmonary toxicity.
A 58-year-old male diabetic patient with severe left ventricular dysfunction and pulmonary arterial hypertension successfully underwent coronary artery by pass grafting (CABG) and was extubated 48 hours after surgery. Patient had atrial fibrillation on 3rd post-operative day requiring loading dose of amiodarone followe...
14,412
Incidence of asymptomatic cerebral microthromboembolism after atrial fibrillation ablation guided by complex fractionated atrial electrogram.
The incidence of cerebral thromboembolism after pulmonary vein isolation (PVI) ranges from 2% to 14%. This study investigated the incidence of cerebral thromboembolism after complex fractionated atrial electrogram (CFAE) ablation with or without PVI.</AbstractText>One hundred consecutive atrial fibrillation (AF) patien...
14,413
Clinical predictors of Fidelis lead failure: report from the Canadian Heart Rhythm Society Device Committee.
Approximately 268,000 Fidelis leads were implanted worldwide until distribution was suspended because of a high rate of early failure. Careful analyses of predictors of increased lead failure hazard are required to help direct future lead design and also to inform decision making on lead replacement. We sought to perfo...
14,414
Dingxin recipe ( ) prevents ischemia/reperfusion-induced arrhythmias via up-regulating prohibitin and suppressing inflammatory responses.
To identify the underlying mechanisms of the protective effects of Dingxin Recipe (: , DXR), a Chinese compound prescription that has been used clinically in China for more than 20 years, on ischemia/reperfusion (I/R)-induced arrhythmias in rat model.</AbstractText>A total of 30 rats were randomly divided into three gr...
14,415
Unrecognized failure of a narrow caliber defibrillation lead: the role of defibrillation threshold testing in identifying an unprotected individual.
In this case report we describe a short circuit in the Riata 1570 defibrillator lead (Riata 1570, St. Jude Medical, St. Paul, MN, USA) that was unsuspected owing to normal lead parameters until defibrillator threshold testing at the time of elective generator change. On this occasion, the short circuit manifested as un...
14,416
Near elimination of ventricular pacing in SafeR mode compared to DDD modes: a randomized study of 422 patients.
SafeR performance versus DDD/automatic mode conversion (DDD/AMC) and DDD with a 250-ms atrioventricular (AV) delay (DDD/LD) modes was assessed toward ventricular pacing (Vp) reduction.</AbstractText>After a 1-month run-in phase, recipients of dual-chamber pacemakers without persistent AV block and persistent atrial fib...
14,417
Arrhythmogenic difference between the left and right atria in a canine ventricular pacing-induced heart failure model of atrial fibrillation.
The detail of biatrial activation during sustained atrial fibrillation (AF) has not been investigated until now.</AbstractText>Five dogs with right ventricular pacing-induced congestive heart failure (CHF) and five normal dogs were included. Biatrial endocardiac mapping was performed using noncontact mapping system.</A...
14,418
Continuous-flow left ventricular assist device support in patients with advanced heart failure: points of interest for the daily management.
Today, continuous-flow left ventricular assist devices (cf-LVADs) are implanted more often in patients with end-stage heart failure. Because of greater durability they can be implanted for an extended period of time. As a result of increased numbers of patients on cf-LVAD support, healthcare professionals should be awa...
14,419
Electromechanical and structural alterations in the aging rabbit heart and aorta.
Aging increases the risk for arrhythmias and sudden cardiac death (SCD). We aimed at elucidating aging-related electrical, functional, and structural changes in the heart and vasculature that account for this heightened arrhythmogenic risk. Young (5-9 mo) and old (3.5-6 yr) female New Zealand White (NZW) rabbits were s...
14,420
Use of beta-blockers for the treatment of cardiac arrest due to ventricular fibrillation/pulseless ventricular tachycardia: a systematic review.
Advanced Life Support guidelines recommend the use of epinephrine during Cardiopulmonary Resuscitation (CPR), as to increase coronary blood flow and perfusion pressure through its alpha-adrenergic peripheral vasoconstriction, allowing minimal rises in coronary perfusion pressure to make defibrillation possible. Contras...
14,421
Ventricular flutter triggered by fever in a patient with Brugada syndrome.
Brugada syndrome is a clinical-electrocardiographic entity predisposing to malignant ventricular arrhythmias. The typical arrhythmia is polymorphic ventricular tachycardia, which can potentially degenerate to ventricular fibrillation. Monomorphic ventricular tachycardia is uncommon. Our group is reporting the case of a...
14,422
Feasibility and safety of dabigatran versus warfarin for periprocedural anticoagulation in patients undergoing radiofrequency ablation for atrial fibrillation: results from a multicenter prospective registry.
The purpose of this study was to evaluate the feasibility and safety of periprocedural dabigatran during atrial fibrillation (AF) ablation.</AbstractText>AF ablation requires optimal periprocedural anticoagulation for minimizing bleeding and thromboembolic complications. The safety and efficacy of dabigatran as a perip...
14,423
Detection and prediction of the onset of human ventricular fibrillation: an approach based on complex network theory.
Ventricular fibrillation is a life-threatening cardiac arrhythmia which deserves quick and reliable detection as well as prediction from human electrocardiogram time series. We constructed networks of human ventricular time series with the visibility graph approach to study the network subgraph phenomenon and motif ran...
14,424
Cardiac resynchronization therapy with or without anatomical reverse remodeling does not affect defibrillation threshold.
Recent clinical trials have documented beneficial reverse-remodeling effects with cardiac resynchronization therapy (CRT). The aim of this study was to investigate the effect of CRT with or without reverse anatomical remodeling of the left ventricle on defibrillation threshold (DFT) levels in a prospective and consecut...
14,425
Estimating outcomes of astronauts with myocardial infarction in exploration class space missions.
We estimate likelihood of presenting rhythms and survival to hospital discharge outcome after acute cardiac ischemia with arrhythmia and/or myocardial infarction (AMI) during long-duration space missions (LDSM) using selected terrestrial cohorts in medical literature. Medical scenarios were risk-stratified by coronary ...
14,426
Propofol-induced coved-type electrocardiogram during catheter ablation of paroxysmal atrial fibrillation. A case of Brugada syndrome?
We report a case of a young man with paroxysmal atrial fibrillation, in whom a characteristic coved-type Brugada pattern developed during catheter ablation performed under sedation with propofol. After immediate discontinuation of the propofol infusion, coved-type ST-segment elevation gradually resolved and no ventricu...
14,427
Indications for cardiac resynchronization therapy: 2011 update from the Heart Failure Society of America Guideline Committee.
Cardiac resynchronization therapy (CRT) improves survival, symptoms, quality of life, exercise capacity, and cardiac structure and function in patients with New York Heart Association (NYHA) functional class II or ambulatory class IV heart failure (HF) with wide QRS complex. The totality of evidence supports the use of...
14,428
Does terfenadine-induced ventricular tachycardia/fibrillation directly relate to its QT prolongation and Torsades de Pointes?
Terfenadine has been reported to cause cardiac death. Hence, we investigated its pro-arrhythmic potential in various in vitro models.</AbstractText>Pro-arrhythmic effects of terfenadine were investigated in rabbit isolated hearts and left ventricular wedge preparations. Also, using whole-cell patch-clamp recording, we ...
14,429
Determinants of mortality in patients with heart failure and atrial fibrillation during long-term follow-up.
Heart failure (HF) and atrial fibrillation (AF) often occur together. Both are independently associated with an increased mortality. Clinical parameters associated with mortality in patients with HF such as left ventricular ejection fraction (LV-EF) and New York Heart Association (NYHA) functional class are influenced ...
14,430
Aging reduces left atrial performance during adrenergic stress in middle aged and older patients.
During adrenergic stress, the influence of age on left atrial (LA) function is unknown. We hypothesized that aging decreases LA total emptying fraction (LAEF) during maximal adrenergic stress. The aim of the study was to determine the influence of aging on LA function during adrenergic stress in middle aged and older p...
14,431
Predictors of local venous complications resulting from electrophysiological procedures.
Thromboembolic complications resulting from radiofrequency catheter ablation (RFCA) have an overall incidence of 0.6%. Multiple intracardiac catheters are often necessary for electrophysiological study and RFCA therapy. Therefore, the placement of multiple venous sheaths in one femoral vein is always required for multi...
14,432
Single-heartbeat electromechanical wave imaging with optimal strain estimation using temporally unequispaced acquisition sequences.
Electromechanical Wave Imaging (EWI) is a non-invasive, ultrasound-based imaging method capable of mapping the electromechanical wave (EW) in vivo, i.e. the transient deformations occurring in response to the electrical activation of the heart. Optimal imaging frame rates, in terms of the elastographic signal-to-noise ...
14,433
Conversion of Persistent Atrial Fibrillation After Radiofrequency Ablation by Ibutilide.
Ablation of peristent AF remains challenging with questions unanswered about what the ideal next step after pulmonary venous isolation should be. Ibutilide is a highly effective class III agent for cardioversion of acute-onset atrial flutter and fibrillation, with limited clinical use due to risks of ventricular pro-ar...
14,434
Left Atrial Diastolic Dysfunction following Catheter Ablation of Atrial Fibrillation.
Radiofrequency catheter ablation (RFCA)-induced thermal injury may cause and/or worsen left atrial (LA) diastolic dysfunction leading to pulmonary hypertension and heart failure in patients with atrial fibrillation (AF), the incidence of which is probably more common than is generally realized. Biplane 2-dimensional ec...
14,435
A Novel Transgenic Mouse Model of Cardiac Hypertrophy and Atrial Fibrillation.
Cardiac hypertrophy is a major risk factor for the development of atrial fibrillation (AF). However, there are few animal models of AF associated with cardiac hypertrophy. In this study, we describe the in vivo electrophysiological characteristics and histopathology of a mouse model of cardiac hypertrophy that develops...
14,436
Ejection fraction and outcomes in patients with atrial fibrillation and heart failure: the Loire Valley Atrial Fibrillation Project.
Heart failure (HF) increases the risk of stroke and thrombo-embolism (TE) in non-valvular atrial fibrillation (NVAF), and is incorporated in stroke risk stratification scores. We aimed to establish the role of ejection fraction (EF) in risk prediction in patients with NVAF and HF.</AbstractText>Patients with NVAF, hist...
14,437
Rapid recovery from congestive heart failure following successful radiofrequency catheter ablation in a patient with late onset of Wolff-Parkinson-White syndrome.
A 56-year-old man was admitted because of palpitations and dyspnea. A 12-lead electrocardiogram showed irregular wide QRS complex tachycardia with a slur at the initial portion of the QRS complex. He had preexisting long-standing persistent atrial fibrillation, but early excitation syndrome had never been noted. Chest ...
14,438
Electrophysiologic characteristics and catheter ablation of ventricular tachyarrhythmias among patients with heart failure on ventricular assist device support.
Ventricular tachyarrhythmias (VT) are common among ventricular assist device (VAD) recipients, yet electrophysiologic (EP) characteristics and catheter ablation outcomes remain uncharacterized.</AbstractText>To evaluate the EP characteristics and catheter ablation outcomes for VTs among heart failure patients on VAD su...
14,439
Paroxysmal atrial fibrillation with silent episodes: intermittent versus continuous monitoring.
Asymptomatic atrial fibrillation (AF) presents the same risk for cardioembolic events as symptomatic AF. Intermittent ECG recordings may be helpful in detecting asymptomatic paroxysmal arrhythmias. The objective of this study was to compare short intermittent heart rhythm recordings with or without symptoms with contin...
14,440
Efficacy and safety of vernakalant in patients with atrial flutter: a randomized, double-blind, placebo-controlled trial.
Vernakalant is a novel, relatively atrial-selective antiarrhythmic agent for conversion of atrial fibrillation (AF) to sinus rhythm. This study examined the safety and efficacy of vernakalant in converting atrial flutter (AFL) to sinus rhythm.</AbstractText>This was a phase 2/3, randomized, double-blind, placebo-contro...
14,441
Potassium-channel mutations and cardiac arrhythmias--diagnosis and therapy.
The coordinated generation and propagation of action potentials within cardiomyocytes creates the intrinsic electrical stimuli that are responsible for maintaining the electromechanical pump function of the human heart. The synchronous opening and closing of cardiac Na(+), Ca(2+), and K(+) channels corresponds with the...
14,442
Cannabinoid 1 (CB1) receptor mediates WIN55, 212-2 induced hypothermia and improved survival in a rat post-cardiac arrest model.
The nonselective Cannabinoid (CB) receptor agonist, WIN55, 212-2, was demonstrated to induce hypothermia and improve post-resuscitation outcomes in a rat post-cardiac arrest model. The present study was to explore the potential mechanisms of WIN55, 212-2 on thermoregulation following resuscitation and to investigate wh...
14,443
Discrete subaortic stenosis 37 years after repair of a ventricular septal defect.
Discrete subaortic stenosis (DSS) is uncommon in adults after surgical correction of congenital heart defects. There are only a few published reports on the occurrence of DSS in adults. We present an adult case with DSS after repair of a ventricular septal defect (VSD). The case was a 44-year old female patient who und...
14,444
Cardioprotective effect of dipeptidyl peptidase-4 inhibitor during ischemia-reperfusion injury.
Dipeptidyl peptidase-4 (DPP-4) inhibitor is a new anti-diabetic drug for type-2 diabetes mellitus patients. Despite its benefits on glycemic control, the effects of DPP-4 inhibitor on the heart during ischemia-reperfusion (I/R) periods are not known. We investigated the effect of DPP-4 inhibitor on cardiac electrophysi...
14,445
Polymorphic ventricular tachycardia in a patient with herpes encephalitis.
We present a patient with polymorphic ventricular tachycardia and subsequent ventricular fibrillation with acquired long QT syndrome secondary to herpes encephalitis.
14,446
Growth differentiation factor-15, a novel biomarker related with disease severity in patients with hypertrophic cardiomyopathy.
The growth differentiation factor 15 (GDF-15) has been shown up-regulated in stress conditions and to have regulatory actions in myocyte hypertrophy. We hypothesized that GDF-15 could be related to disease severity and functional status in patients with hypertrophic cardiomyopathy (HCM).</AbstractText>We performed a st...
14,447
Amiodarone (Nexterone) injection for the treatment and prophylaxis of frequently recurring ventricular fibrillation.
Intravenous (IV) amiodarone is the most used and effective drug to manage life-threatening ventricular arrhythmias. However, its administration is associated with important adverse effects, the most frequent of which is hypotension. Nexterone&#xae; is a novel IV amiodarone formulation, proved to be devoid of hypotensiv...
14,448
Atrial fibrillation: established and innovative methods of evaluation and treatment.
5% to 8% of 70-year-olds and some 10% of persons over age 80 have atrial fibrillation (AF).</AbstractText>Selective literature review.</AbstractText>New scoring schemes (CHA(2)DS(2)-VASc score, HAS-BLED score) have been introduced to enable more accurate estimation of the risk of stroke and hemorrhage in patients with ...
14,449
Effects of testosterone on norepinephrine release in isolated rat heart.
The effects of testosterone on norepinephrine release were investigated in the isolated rat hearts. Sprague-Dawley male rats (n=120) were randomized to testosterone and control groups. The rats in testosterone group were perfused with modified Krebs-Henseleit buffer containing different concentrations of testosterone (...
14,450
[Evaluation of clinical and demographic characteristics and their association with length of hospital stay in patients admitted to cardiac intensive care unit with the diagnosis of acute heart failure].
Despite increasing incidence, data regarding clinical and demographic characteristics of patients with acute heart failure (AHF) admitted to cardiac intensive care unit (ICU) are inconclusive. The aim of this study was to assess the presentation characteristics and factors determining the length of hospital stay in thi...
14,451
Prediction protocol for neurological outcome for survivors of out-of-hospital cardiac arrest treated with targeted temperature management.
To identify patients who can obtain the full benefit from targeted temperature management (TTM) after out-of-hospital cardiac arrest.</AbstractText>We performed a retrospective observational study of comatose patients treated with TTM after an out-of-hospital cardiac arrest from January 2006 to February 2011. Neurologi...
14,452
Unusual case of right atrial reinfarction.
It is well known that atrial infarctions are rare comparing to the ventricular. They cannot easily be verified on ECG and the standard autopsy technique does not include a detailed review of the atrial wall, so the atrial infarction often remains undiagnosed. A 63-year-old male was treated and died in an intensive care...
14,453
Right intra-atrial catheter placement for hemodialysis in patients with multiple venous failure.
The purpose of this study is to evaluate the efficacy and safety of direct right atrial catheter insertion for hemodialysis in patients with multiple venous access failure. We retrospectively evaluated the charts of 27 patients with multiple venous access failure who had intra-atrial dialysis catheter placement between...
14,454
Early increase in blood glucose in patients resuscitated from out-of-hospital ventricular fibrillation predicts poor outcome.
To describe the trend of blood glucose immediately after successful resuscitation from out-of-hospital ventricular fibrillation.</AbstractText>Data from cardiac arrest registry supplemented with blood glucose data were analyzed in this population-based observational study. Between 2005 and 2009, a total of 170 adult pa...
14,455
The natural history of preclinical diastolic dysfunction: a population-based study.
Preclinical diastolic dysfunction (PDD) has been broadly defined as subjects with left ventricular diastolic dysfunction, without the diagnosis of congestive heart failure (HF) and with normal systolic function. Our objective was to determine the risk factors associated with the progression from PDD (stage B) HF to sym...
14,456
Device troubleshooting: cross connection of ventricular leads in a patient with decreased right ventricular electrical activity.
A patient with cardiac sarcoidosis showed low R-wave amplitude in the entire right ventricle (RV). To troubleshoot this, a left ventricular (LV) lead was implanted in the coronary vein. The pace/sense terminal of the defibrillation lead was connected to LV:IS-1 of the defibrillator. Conversely, the LV lead was connecte...
14,457
Atrial burst pacing with biphasic and monophasic waveforms for atrial fibrillation.
Biphasic pacing is a novel mode of pacing that was suggested to increase cardiac conduction velocity as compared with cathodal monophasic pacing. We aimed to evaluate the safety and efficacy of rapid atrial pacing to convert atrial fibrillation (AF) to normal sinus rhythm.</AbstractText>Multiple biphasic (anodal/cathod...
14,458
[Arrhythmogenic effects of alcohol].
Acute or chronic excessive consumption of alcohol can cause cardiac arrhythmias, particularly supraventricular tachyarrhythmias. Experimental and clinical data show that chronic excessive alcohol ingestion has a destructive role on cardiac tissue, which significantly deteriorates the rhythm and contractile activity, ma...
14,459
Integration of intracardiac echocardiographic imaging of the left atrium with electroanatomic mapping data for pulmonary vein isolation: first-in-Greece experience with the CartoSound&#x2122; system and brief literature review.
Intracardiac echocardiography (ICE) offers the ability to image the left atrium in order to reconstruct a three-dimensional model that can be integrated with electroanatomic data to guide pulmonary vein isolation. We report a case series representing the first-in-Greece experience with the CartoSound module.</AbstractT...
14,460
Modeling defibrillation of the heart: approaches and insights.
Cardiac defibrillation, as accomplished nowadays by automatic, implantable devices (ICDs), constitutes the most important means of combating sudden cardiac death. While ICD therapy has proved to be efficient and reliable, defibrillation is a traumatic experience. Thus, research on defibrillation mechanisms, particularl...
14,461
Left atrial volume and function in patients with Behcet's disease assessed by real-time three-dimensional echocardiography.
Beh&#xe7;et's disease (BD), a multisystemic inflammatory disorder, has been associated with a number of cardiovascular dysfunctions, including endomyocardial fibrosis of the right heart, atrial fibrillation, ventricular arrhythmias and sudden cardiac death. The incidence and nature of cardiac involvement in BD are not ...
14,462
Predictors of long-term benefit of cardiac resynchronization therapy in patients with right bundle branch block.
The aims of this study were: (i) to characterize consecutive cardiac resynchronization therapy (CRT) recipients with right bundle branch block (RBBB) in comparison with left bundle branch block (LBBB) and (ii) to identify independent predictors of long-term outcome among CRT recipients with RBBB. The presence of RBBB h...
14,463
[Progress in cardiac electrophysiology and arrhythmias].
This article contains a review of the most important publications in the field of cardiac electrophysiology and arrhythmias that have appeared in the last year. Publications were selected because they reported important scientific developments or significant improvements in the devices or invasive techniques used for t...
14,464
A randomized trial of compression first or analyze first strategies in patients with out-of-hospital cardiac arrest: results from an Asian community.
It is still under debate whether a period of cardiopulmonary resuscitation should be performed prior to rhythm analysis for defibrillation for out of hospital cardiac arrests (OHCA). This study compared outcomes of OHCA treated by "compression first" (CF) versus "analyze first" (AF) strategies in an Asian community wit...
14,465
Atrial electrical and structural remodeling associated with longstanding pulmonary hypertension and right ventricular hypertrophy in humans.
Pulmonary hypertension (PH) is common to a range of cardiopulmonary conditions and is associated with atrial arrhythmias. However, little is known of the isolated atrial effects of PH and right atrial dilatation (RA) in humans. To avoid the confounding effects of PH-associated disease states, we performed detailed elec...
14,466
Studying semblances of a true killer: experimental model of human ventricular fibrillation.
It is unknown whether ventricular fibrillation (VF) studied in experimental models represents in vivo human VF. First, we examined closed chest in vivo VF induced at defibrillation threshold testing (DFT) in four patients with ischemic cardiomyopathy pretransplantation. We examined VF in these same four hearts in an ex...
14,467
Intramural optical mapping of V(m) and Ca(i)2+ during long-duration ventricular fibrillation in canine hearts.
Intramural gradients of intracellular Ca(2+) (Ca(i)(2+)) Ca(i)(2+) handling, Ca(i)(2+) oscillations, and Ca(i)(2+) transient (CaT) alternans may be important in long-duration ventricular fibrillation (LDVF). However, previous studies of Ca(i)(2+) handling have been limited to recordings from the heart surface during sh...
14,468
Combined cardiac magnetic resonance imaging and C-reactive protein levels identify a cohort at low risk for defibrillator firings and death.
Annually, &#x2248;80,000 Americans receive guideline-based primary prevention implantable cardioverter-defibrillators (ICDs), but appropriate firing rates are low. Current selection criteria for ICDs rely on left ventricular ejection fraction, which lacks sensitivity and specificity. Because scar-related myocardial tis...
14,469
Assessment of left atrial mechanics in patients with atrial fibrillation: comparison between two-dimensional speckle-based strain and velocity vector imaging.
Two-dimensional (2D) speckle tracking-derived left atrial (LA) strain (&#x3b5;) facilitates comprehensive evaluation of LA contractile, reservoir, and conduit function; however, its dependence on the individual software used for assessment has not been evaluated. The aim of this study was to compare LA &#x3b5; derived ...
14,470
Association of heart rate variability with arrhythmic events in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia.
Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is associated with an increased risk of sudden cardiac death (SCD). Risk stratification of ARVC/D patients, however, remains an unresolved issue. In this study we investigated whether heart rate variability (HRV) can be helpful in identifying ARVC/D pat...
14,471
Radiofrequency catheter ablation in children with supraventricular tachycardias: intermediate term follow up results.
Radiofrequency (RF) catheter ablation represents an important advance in the management of children with cardiac arrhythmias and has rapidly become the standard and effective line of therapy for supraventricular tachycardias (SVTs) in pediatrics. The purpose of this study was to evaluate the intermediate term follow up...
14,472
[Amiodarone and thyroid dysfunction].
Amiodarone is a structural analogue of thyroid hormone, and some of its anti-arrhythmic actions and toxicity are attributable to its interaction with nuclear receptors of thyroid hormones. Being highly lipophilic, amiodarone is concentrated in many tissues and is eliminated, consequently, very slowly. It is preferably ...
14,473
Automatic continuous ECG monitoring system for over-drug detection in Brugada Syndrome.
This paper is concerned with the automatic control of drug administration in patients suffering from Brugada Syndrome (BS). Drugs such as flecainide, procainamide, ajmaline and pilsicainide should be administrated under carefully controlled electrocardiogram (ECG) monitoring given that the treatment must be stopped if ...
14,474
Detection and removal of ventricular ectopic beats in atrial fibrillation recordings via principal component analysis.
Ectopic beats are early heart beats with remarkable large amplitude that provoke serious disturbances in the analysis of electrocardiograms (ECG). These beats are very common in atrial fibrillation (AF) and are the source of important residua when the QRST is intended to be removed. Given that QRST cancellation is a bi...
14,475
Interpretation of coarse-graining of Lempel-Ziv complexity measure in ECG signal analysis.
Lempel-Ziv (LZ) complexity measure has been applied to classify ventricular tachycardia (VT) and ventricular fibrillation (VF). The coarse-graining process plays a crucial role in the LZ complexity measure analysis, which directly affects the separating performance of VT and VF in ECG signal analysis. The question of d...
14,476
Time-domain ECG signal analysis based on smart-phone.
In this paper, a time domain algorithm architecture is presented and implemented on a smart-phone for ECG signal analysis. Using the QRS detection algorithm suggested by Pan-Tompkins and the beat classification method, the heart beats are detected and classified as normal beats and premature ventricular contractions (P...
14,477
Wavelet-based features for characterizing ventricular arrhythmias in optimizing treatment options.
Ventricular arrhythmias arise from abnormal electrical activity of the lower chambers (ventricles) of the heart. Ventricular tachycardia (VT) and ventricular fibrillation (VF) are the two major subclasses of ventricular arrhythmias. While VT has treatment options that can be performed in catheterization labs, VF is a l...
14,478
Ventricular fibrillation risk estimation for conducted electrical weapons: critical convolutions.
The TASER&#xae; Conducted Electrical Weapon (CEW) is used by law enforcement agencies about 900 times per day worldwide and has been shown to reduce suspect and officer injuries by about 65%. However, since a CEW delivers rapid electrical pulses through injected probes, the risk of inducing ventricular fibrillation (VF...
14,479
Ventricular fibrillation threshold of rapid short pulses.
The risk of VF (ventricular fibrillation) from continuous AC utility (50/60 Hz) power has been well quantified and is reflected in accepted standards. Similarly, the required charge for a single pulse delivered during the T-wave of the ECG is also quantified. However, there are no studies that deal with the VF risk of ...
14,480
Predicting refibrillation from pre-shock waveforms in optimizing cardiac resuscitation.
Ventricular fibrillation (VF) is a lethal cardiac arrhythmia that if untreated within minutes of its occurrence will lead to sudden cardiac death. Defibrillation using electric shocks is the only choice of treatment to restore the heart to normal rhythm especially in out-of-the-hospital VF incidents. Refibrillation (i....
14,481
Relating spatial heterogeneities to rotor formation in studying human ventricular fibrillation.
Ventricular fibrillation (VF) occurs due to disorganized electrical activity in the ventricles. This leads to rapid uncoordinated contractions of the ventricles and sudden cardiac death if not treated within minutes of its occurrence. The mechanism of VF initiation and maintenance is still elusive, however the mother r...
14,482
Targeting cardiac fibrosis: a new frontier in antiarrhythmic therapy?
Cardiac fibrosis is known to alter cardiac conduction and promote reentry. Recent evidence indicates that fibrosis characterized by increased interstitial collagen accumulation and increased myofibroblast proliferation also promotes enhanced automaticity and early afterdepolarizations (EADs) causing triggered activity....
14,483
Relation of components of the metabolic syndrome to left ventricular geometry in hispanic and non-hispanic black adults.
Left ventricular (LV) hypertrophy is an independent predictor of increased cardiovascular morbidity and mortality. It remains unclear whether components of the metabolic syndrome are associated with LV hypertrophy.</AbstractText>Accordingly, we analyzed echocardiograms in 192 consecutive ambulatory patients referred fo...
14,484
Characteristics of induced ventricular fibrillation cycle length in symptomatic Brugada syndrome patients.
Limited information is available on the ventricular fibrillation (VF) spectrum in Brugada syndrome (BS) patients. We clarified differences in the VF cycle length (CL) using fast-Fourier transformation (FFT) analysis in symptomatic and asymptomatic BS patients.</AbstractText>VF was induced by pacing from the right ventr...
14,485
96&#xa0;hours ECG monitoring for patients with ischemic cryptogenic stroke or transient ischaemic attack.
Atrial fibrillation (AF) is intermittent in 30% of patients with cardioembolic stroke and, therefore, might not be seen in a single standard ECG recording. The aim of this study was to evaluate if prolonged ECG monitoring (96&#xa0;h) finds episodes of intermittent AF beyond the 24&#xa0;h ECG monitoring in patients with...
14,486
Unmasking of J waves during right coronary angiography in patients with spontaneous coronary spasms and ventricular fibrillation.
We encountered two consecutive cases with spontaneous ST elevation due to right coronary spasms and subsequent ventricular fibrillation (VF). Their 12-lead ECGs on anterior chest pain showed elevation of ST-segments in the inferior leads, but coronary angiography (CAG) revealed no significant stenosis. Both cases showe...
14,487
Molecular mechanisms of therapeutic hypothermia on neurological function in a swine model of cardiopulmonary resuscitation.
To explore the molecular mechanisms by which mild hypothermia following resuscitation improves neurological function in a porcine model of cardiac arrest.</AbstractText>Thirty-three inbred Chinese Wuzhishan (WZS) minipigs were used. After 8 min of untreated ventricular fibrillation (VF), the surviving animals (n=29) we...
14,488
United States national prevalence of electrocardiographic abnormalities in black and white middle-age (45- to 64-Year) and older (&#x2265;65-Year) adults (from the Reasons for Geographic and Racial Differences in Stroke Study).
A United States national sample of 20,962 participants (57% women, 44% blacks) from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study provided general population estimates for electrocardiographic (ECG) abnormalities among black and white men and women. The participants were recruited from 200...
14,489
Prognostic value of tricuspid annular tissue Doppler velocity in heart failure with atrial fibrillation.
Right ventricular function is associated with long-term outcomes of heart failure (HF), particularly with atrial fibrillation (AF). The aim of this study was to evaluate the prognostic value of Doppler tissue imaging at the mitral and tricuspid annuli in patients with HF and AF.</AbstractText>In this prospective observ...
14,490
Worsening dyspnea in a man with 2 hearts.
We report a case of dyspnea in a 71-year-old man who underwent heterotopic heart transplantation in 2003. At presentation, electrocardiography showed ventricular fibrillation of the native heart and then a progression to both donor and recipient hearts. Synchronized electrical cardioversion restored sinus rhythm and re...
14,491
The involvement of gap junctions in the delayed phase of the protection induced by cardiac pacing in dogs.
The present study has examined the role of GJ (gap junctions) in the delayed anti-arrhythmic effect of cardiac pacing, with particular reference to the time-course changes in Cx43 (connexin43) expression both after pacing (4&#xd7;5&#xa0;min, at a rate of 240 beats/min) and 24&#xa0;h later, when the dogs were subjected ...
14,492
[Comparative study between landiolol and amiodarone for therapeutic efficacy after open heart surgery].
Tachyarrhythmia, especially atrial fibrillation, remains as a common complication after open heart surgery and sometimes leads to fatal condition. Many reports showed that landiolol (ultra short-acting beta one blocker) and amiodarone were effective against postoperative atrial fibrillation (POAF). However, there were ...
14,493
Atrial fibrillation management in Asia: from the Asian expert forum on atrial fibrillation.
Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, is associated with increased morbidity and mortality. AF has a slightly lower incidence and prevalence in Asian populations than in Western populations, but the associated relative risk of stroke and mortality is similar. Patients with AF in Asia h...
14,494
Hypothermia therapy: neurological and cardiac benefits.
Due to its protective effect on the brain and the myocardium, hypothermia therapy (HT) has been extensively studied in cardiac arrest patients with coma as well as in patients presenting with acute myocardial infarction (MI). In the setting of cardiac arrest, randomized studies have shown that HT decreases mortality an...
14,495
Characteristics of electrocardiographic repolarization in acute myocardial infarction complicated by ventricular fibrillation.
Some de- and re-polarization patterns can reflect an increased risk of ventricular tachyarrhythmias. We studied whether some electrocardiographic (ECG) patterns are able to predict the development of ventricular fibrillation (VF) during acute myocardial infarction (MI).</AbstractText>We compared the patterns of ST-T se...
14,496
Role of inflammation in early atrial fibrillation recurrence.
Outcome of rhythm control in atrial fibrillation (AF) is still poor due to various mechanisms involved in the initiation and perpetuation of AF. Differences in timing of AF recurrence may depend on different types of mechanisms. The aim of this study was to assess the mechanisms involved in early AF recurrence in patie...
14,497
Epidemiology of out-of hospital pediatric cardiac arrest due to trauma.
To determine the epidemiology and survival of pediatric out-of-hospital cardiac arrest (OHCA) secondary to trauma.</AbstractText>The CanAm Pediatric Cardiac Arrest Study Group is a collaboration of researchers in the United States and Canada sharing a common goal to improve survival outcomes for pediatric cardiac arres...
14,498
Cardiac movement identified on prehospital echocardiography predicts outcome in cardiac arrest patients.
The prognostic value of emergency echocardiography (EE) in the management of cardiac arrest patients has previously been studied in an in-hospital setting. These studies mainly included patients who underwent cardiopulmonary resuscitation (CPR) by emergency medicine technicians at the scene and who arrived at the emerg...
14,499
Serum potassium levels and mortality in acute myocardial infarction.
Clinical practice guidelines recommend maintaining serum potassium levels between 4.0 and 5.0 mEq/L in patients with acute myocardial infarction (AMI). These guidelines are based on small studies that associated low potassium levels with ventricular arrhythmias in the pre-&#x3b2;-blocker and prereperfusion era. Current...