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14,800 | Heart failure, atrial fibrillation and neuromuscular disorders influence mortality in left ventricular hypertrabeculation/noncompaction. | The prognosis of patients with left ventricular hypertrabeculation/noncompaction (LVHT) is controversial. The aim of the study was to assess parameters influencing mortality and to compare the mortality of LVHT patients with that of the general population of Austria.</AbstractText>Included were patients with LVHT diagn... |
14,801 | Prognostic factors of atrial fibrillation following elective coronary artery bypass grafting: the impact of quantified intraoperative myocardial ischemia. | Atrial fibrillation (AF) occurs in 28-33% of the patients undergoing coronary artery revascularization (CABG). This study focuses on both pre- and peri-operative factors that may affect the occurrence of AF. The aim is to identify those patients at higher risk to develop AF after CABG.</AbstractText>Two patient cohorts... |
14,802 | Fusion of imaging technologies: how, when, and for whom? | Over the past decade, electroanatomic mapping has emerged as a useful tool for complex ablation procedures. A more recent advancement is the development of image integration. Image integration refers to the process of registering a previously acquired MRI or CT scan of the heart with the mapping space during the ablati... |
14,803 | Electrophysiologic profile of dronedarone on the ventricular level: beneficial effect on postrepolarization refractoriness in the presence of rapid phase 3 repolarization. | Dronedarone (D) is developed to maintain sinus rhythm in patients suffering from atrial fibrillation. The aim of the present study was to investigate, whether dronedarone also has an antiarrhythmic potential in the ventricle and to elucidate the mechanisms for its low proarrhythmic potential in an experimental whole he... |
14,804 | Quantitative waveform measures of the electrocardiogram as continuous physiologic feedback during resuscitation with cardiopulmonary bypass. | There are few if any real-time physiologic measures that currently provide feedback during resuscitation from cardiac arrest. Such measures could be used to guide therapy not simply based on process guidelines but on the physiologic response of the patient from moment to moment. To this end, we applied an existing tech... |
14,805 | Impact of resuscitation system errors on survival from in-hospital cardiac arrest. | An estimated 350,000-750,000 adult, in-hospital cardiac arrest (IHCA) events occur annually in the United States. The impact of resuscitation system errors on survival during IHCA resuscitation has not been evaluated. The purpose of this paper was to evaluate the impact of resuscitation system errors on survival to hos... |
14,806 | Cardiovascular protection with danshensu in spontaneously hypertensive rats. | The objective of the present study was to evaluate the cardiovascular protective effects of Danshensu, a water-soluble active component of Danshen, in spontaneously hypertensive rats (SHR). SHR (male, 9 weeks old, n=30) were divided into three groups: 1) saline control (n=10); 2) a Danshensu (10 mg/kg/d, intraperitonea... |
14,807 | Pulmonary hypertension adversely affects short- and long-term survival after mitral valve operation for mitral regurgitation: implications for timing of surgery. | We investigated the impact of preoperative pulmonary hypertension (PH) on early and late outcomes after mitral valve operation for mitral regurgitation.</AbstractText>Systolic pulmonary artery pressure (sPAP) was measured before operation in 873 consecutive patients who underwent mitral valve surgery for mitral regurgi... |
14,808 | Improvement in the assessment of diastolic function in a clinical echocardiography laboratory following implementation of a quality improvement initiative. | The aim of this study was to demonstrate improvement in the characterization of diastolic function in the routine practice of a clinical echocardiography laboratory after the implementation of a quality improvement initiative. The echocardiographic analysis of left ventricular (LV) diastolic dysfunction is an inherentl... |
14,809 | Late outcome of 132 Senning procedures after 20 years of follow-up. | Risk factors and rates of reoperation, arrhythmias, systemic right ventricular dysfunction (RVD), and late death after a Senning procedure were investigated.</AbstractText>One-hundred thirty-two patients underwent a Senning operation between 1977 and 2004 (105 simple and 27 complex transpositions of the great arteries)... |
14,810 | [Premature sudden death--consider serious familial heart rhythm disturbances]. | We describe 3 patients from a region in the centre of the Netherlands with several relatives who died prematurely from sudden cardiac arrest. These premature deaths appeared to be caused by a unique familial sudden death syndrome. These patients and their relatives did not present any distinguishable signs, symptoms or... |
14,811 | [Amiodaron: decades of administration]. | The review of long-term international clinical experience with amiodaron covers pharmacological properties of the drug, mechanisms of development of its pharmacodynamic effects basing on its action on ionic channels, receptors, impact on thyroid function. Unique pharmacokinetics of amiodaron, high antiarrhythmic effica... |
14,812 | A case of Brugada syndrome coexisting with vasospastic angina: Caution should be taken when using calcium channel blockers. | Although calcium channel blockers have been reported to aggravate Brugada-type electrocardiogram (ECG) abnormalities, there have been few reports in clinical settings. We present a case of Brugada syndrome coexisting with vasospastic angina, in whom Brugada-type ST-segment elevation was aggravated and ventricular fibri... |
14,813 | Clinical and microbiological profiles of infective endocarditis in a tertiary hospital in Aseer region, Saudi Arabia. | We aimed to evaluate demographic data, underlying cardiac abnormalities, clinical profile, microbiological features, treatments and complications of infective endocarditis (IE) in a tertiary hospital in Aseer region, Saudi Arabia.</AbstractText>A retrospective study of all cases with the diagnosis of definite endocardi... |
14,814 | Evaluation of QT and P wave dispersion and mean platelet volume among inflammatory bowel disease patients. | In inflammatory bowel disease (IBD) number of thromboembolic events are increased due to hypercoagulupathy and platelet activation. Increases in mean platelet volume (MPV) can lead to platelet activation, this leads to thromboembolic events and can cause acute coronary syndromes. In IBD patients, QT-dispersion and P-wa... |
14,815 | Prognostic utility of T-wave alternans in a real-world population of patients with left ventricular dysfunction: the PREVENT-SCD study. | The predictive value of T-wave alternans (TWA) for lethal ventricular tachyarrhythmia in patients with left ventricular (LV) dysfunction is controversial. Also, long-term arrhythmia risk of patients ineligible for the TWA test is unknown.</AbstractText>This was a multicenter, prospective observational study of patients... |
14,816 | Renal sympathetic denervation for treatment of electrical storm: first-in-man experience. | Sympathetic activity plays an important role in the pathogenesis of ventricular tachyarrhythmia. Catheter-based renal sympathetic denervation (RDN) is a novel treatment option for patients with resistant hypertension, proved to reduce local and whole-body sympathetic activity.</AbstractText>Two patients with chronic he... |
14,817 | Incidence and outcome of out-of-hospital cardiac arrest with public-access defibrillation. A descriptive epidemiological study in a large urban community. | Detailed characteristics of those who experience an out-of-hospital cardiac arrest (OHCA) with public-access defibrillation (PAD) are unknown.</AbstractText>A prospective, population-based observational study involving consecutive OHCA patients with emergency responder resuscitation attempts was conducted from July 1, ... |
14,818 | Isolated severe tricuspid regurgitation in a post pneumonectomy patient with chronic atrial fibrillation. | Severe primary tricuspid regurgitation is a rare entity, with most cases of tricuspid regurgitation being functional and secondary to pulmonary hypertension from left heart pathologies. We report an unusual case of a female patient with a history of left pneumonectomy and chronic atrial fibrillation many years earlier,... |
14,819 | [Arrhythmology today: risks associated with anti-arrhythmic therapy in an internal medicine outpatient clinic]. | Arhytmology that is focused on diagnostics and therapy of heart rhythm disturbances and their complications has undergone dramatic development in last 2 decades. Widespread use of catheter ablation, introduction of implantable cardioverter-defibrillators for prevention of sudden cardiac death and finally, development o... |
14,820 | Role of clonidine in perioperative acute atrial fibrillation. | We report a case of acute onset atrial fibrillation (AF) that presented for emergency surgery where rate control and sinus rhythm were successfully achieved using clonidine. Patient had acute AF with high blood pressure. Metoprolol failed to decrease the ventricular rate and blood pressure but with clonidine, we could ... |
14,821 | Reversible cardiac conduction block and defibrillation with high-frequency electric field. | Electrical impulse propagation is an essential function in cardiac, skeletal muscle, and nervous tissue. Abnormalities in cardiac impulse propagation underlie lethal reentrant arrhythmias, including ventricular fibrillation. Temporary propagation block throughout the ventricular myocardium could possibly terminate thes... |
14,822 | Dofetilide reduces the frequency of ventricular arrhythmias and implantable cardioverter defibrillator therapies. | Patients with an implanted cardioverter defibrillator (ICD) and ventricular arrhythmias leading to ICD therapies have poor clinical outcomes and quality of life. Antiarrhythmic agents and catheter ablation are needed to control these arrhythmias. Dofetilide has only been approved for the treatment of atrial fibrillatio... |
14,823 | Atrial Coronary Arteries: Anatomy And Atrial Perfusion Territories. | Coronary anatomy has traditionally focused on ventricular circulation. This is largely due to the extent to which coronary artery disease contributes to ischemic heart disease through ventricular myocardial damage. Atrial fibrillation and other tachyarrhythmias that involve the atria, however, remain a major cause of m... |
14,824 | Ascorbic acid mitigates the myocardial injury after cardiac arrest and electrical shock. | To examine the effects of ascorbic acid (AA) administrated during cardiopulmonary resuscitation (CPR) on the myocardial injury in a rat model of ventricular fibrillation (VF) and electrical shock (ES).</AbstractText>VF was induced in male Wistar rats and left untreated for 5 min, followed by 1 min of CPR, and... |
14,825 | Living with life-saving technology - coping strategies in implantable cardioverter defibrillators recipients. | To describe coping strategies and coping effectiveness in recipients with an implantable cardioverter defibrillator and to explore factors influencing coping.</AbstractText>Implantable cardioverter defibrillators are documented as saving lives and are used to treat ventricular tachycardia and ventricular fibrillation. ... |
14,826 | A 35-year-old pregnant woman presenting with sudden cardiac arrest secondary to peripartum cardiomyopathy. | We present a case of successful resuscitation from cardiac arrest after 25 minutes of ventricular fibrillation (VF) secondary to peripartum cardiomyopathy. This case highlights a rare disease, but also, more importantly, the successful use of the five links of survival: early access to 9-1-1, early cardiopulmonary resu... |
14,827 | Long-term use and tolerability of irbesartan for control of hypertension. | In this review, we discuss the pharmacological and clinical properties of irbesartan, a noncompetitive angiotensin II receptor type 1 antagonist, successfully used for more than a decade in the treatment of essential hypertension. Irbesartan exerts its antihypertensive effect through an inhibitory effect on the pressur... |
14,828 | Relationship between R-R interval variation and left ventricular function in sinus rhythm and atrial fibrillation as estimated by means of heart rate variability fraction. | Reduced heart rate variability (HRV) is associated with a poor outcome in patients with sinus rhythm (SR) or atrial fibrillation (AF). However, cut-off points for HRV measures differ between SR and AF. We hypothesized that a global index of 24-hour HRV based on evaluation of scatterplot would describe HRV irrespective ... |
14,829 | Frequency, determinants and outcome of pulmonary hypertension in patients with aortic valve stenosis. | The frequency, causes and prognostic implications of pulmonary hypertension (PHT) in patients with severe aortic stenosis (AS) are not well defined. The objectives of this study were to determine the frequency of PHT [pulmonary artery systolic pressure (PASP) >50 mm Hg] in patients with severe AS, identify the facto... |
14,830 | Ventricular tachycardia or ventricular fibrillation occurs less often in patients with left bundle branch block and combined resynchronization and defibrillators than in patients with narrow QRS and conventional defibrillators. | Mortality in chronic heart failure (CHF) patients with left bundle branch block (LBBB) is high. Cardiac resynchronization therapy (CRT) reduces symptoms and mortality in CHF patients with LBBB. Whether CRT promotes or prevents ventricular tachycardia (VT)/ventricular fibrillation (VF) remains controversial, however. Th... |
14,831 | Coupled pacing controls rapid heart rates better than paired pacing during atrial fibrillation. | Delivery of a ventricular extrastimulus shortly after the effective refractory period (ERP) of a sensed (coupled pacing; CP) or a paced (paired pacing; PP) ventricular event can instantly decrease the mechanical pulse rate (MPR) during rapidly conducting atrial fibrillation (AF). We compared the short-term rate-control... |
14,832 | Subarachnoid hemorrhage causing cardiopulmonary arrest: resuscitation profiles and outcomes. | Aneurysmal subarachnoid hemorrhage (SAH) is a common cause of cardiopulmonary arrest (CPA). The outcomes of SAH patients presenting with CPA are extremely poor, and long-term survivors have occasionally been reported, but the circumstances under which SAH-CPA patients achieve long-term survival are unclear. Neurosurgeo... |
14,833 | Paediatric arrhythmias in the emergency department. | Emergency department (ED) staff need to rapidly establish accurate diagnosis and management for children with arrhythmias. Limited data are available on the presenting features, epidemiology and management of arrhythmias encountered in the ED. The aim of this study was to characterise the incidence, presenting features... |
14,834 | In vivo porcine left atrial wall stress: Effect of ventricular tachypacing on spatial and temporal stress distribution. | Animal models of ventricular tachypacing (VTP) have been successfully used to reproduce the relevant features observed in patients with atrial fibrillation, such as increased atrial pressure and volume, ion-channel alterations and fibrosis. After performing VTP on a healthy Yorkshire pig, we measured an increase in vol... |
14,835 | Strong coherence between heart rate variability and intracardiac repolarization lability during biventricular pacing is associated with reverse electrical remodeling of the native conduction and improved outcome. | Reverse electrical remodeling (RER) of the native conduction with cardiac resynchronization therapy (CRT) is associated with decreased mortality and antiarrhythmic effect of CRT. Still, mechanisms of RER are largely unknown. In this study, we explored repolarization lability during biventricular pacing.</AbstractText>T... |
14,836 | Arrhythmic manifestations in patients with congenital left ventricular aneurysms and diverticula. | Congenital left ventricular aneurysms and diverticula (LVA/Ds) are rare cardiac malformations that can be detected using echocardiography or other imaging techniques. Some of these patients present with ventricular arrhythmias. This study investigated clinical characteristics of patients with congenital LVA/D presentin... |
14,837 | Comparison of invasive and non-invasive measurements of haemodynamic parameters in patients with advanced heart failure. | Measurement of haemodynamic parameters using a Swan-Ganz catheter is of clinical importance in patients with advanced heart failure; however, its applicability is limited due to its invasiveness. The aim of the study was to estimate the concordance between invasive and non-invasive measurements of haemodynamic paramete... |
14,838 | Short-term exercise preserves myocardial glutathione and decreases arrhythmias after thiol oxidation and ischemia in isolated rat hearts. | The purpose of this study was to determine if exercise (Ex) protects hearts from arrhythmias induced by glutathione oxidation or ischemia-reperfusion (I/R). Female Sprague-Dawley rats were divided into two experimental groups: sedentary controls (Sed) or short-term Ex (10 days of treadmill running). Twenty-four hours a... |
14,839 | Deterioration of mitral valve competence after the repair of atrial septal defect in adults. | Although mild mitral regurgitation (MR) associated with atrial septal defect (ASD) is believed to improve by ASD closure alone, new-onset MR or aggravation of preexisting mild MR may also develop after ASD closure. We sought to determine the preoperative risk factors for the postoperative deterioration of mitral valve ... |
14,840 | Incidence and predictors of implantable cardioverter-defibrillator therapy in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy undergoing implantable cardioverter-defibrillator implantation for primary prevention. | The purpose of this study was to define the incidence and predictors of implantable cardioverter-defibrillator (ICD) therapy in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) after placement of an ICD for primary prevention.</AbstractText>Patients with a diagnosis of ARVD/C often recei... |
14,841 | Evidence of atrial functional mitral regurgitation due to atrial fibrillation: reversal with arrhythmia control. | The purpose of this study was to determine whether atrial fibrillation (AF) might cause significant mitral regurgitation (MR), and to see whether this MR improves with restoration of sinus rhythm.</AbstractText>MR can be classified by leaflet pathology (organic/primary and functional/secondary) and by leaflet motion (n... |
14,842 | Vagal activity modulates spontaneous augmentation of J-wave elevation in patients with idiopathic ventricular fibrillation. | Although J-wave elevation in the inferolateral leads could be related to idiopathic ventricular fibrillation (IVF), little is known about the pathophysiologic characteristics of J-wave elevation in patients with IVF.</AbstractText>This study aimed to determine the relationship between augmentation of J-wave elevation a... |
14,843 | Clinical impact of the number of extrastimuli in programmed electrical stimulation in patients with Brugada type 1 electrocardiogram. | Use of programmed electrical stimulation (PES) for risk stratification of Brugada syndrome (BrS) is controversial.</AbstractText>To elucidate the role of the number of extrastimuli during PES in patients with BrS.</AbstractText>Consecutive 108 patients with type 1 electrocardiogram (104 men, mean age 46 ± 12 years... |
14,844 | Isolating the pulmonary veins as first-line therapy in patients with lone paroxysmal atrial fibrillation using the cryoballoon. | Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice. Nowadays, catheter-based ablative approaches are mainly reserved for drug-refractory patients. However, the value of an ablative therapy as a first-line alternative remains elusive. The aim of our study was to analyse the acute pro... |
14,845 | Atrial function after left atrial epicardial cryoablation for atrial fibrillation in patients undergoing mitral valve surgery. | To explore the effects on atrial and ventricular function of restoring sinus rhythm (SR) after epicardial cryoablation and closure of the left atrial appendage (LAA) in patients with mitral valve disease and atrial fibrillation (AF) undergoing surgery.</AbstractText>Sixty-five patients with permanent AF were randomized... |
14,846 | A case of exhaustion of implantable cardioverter defibrillator therapies due to inappropriate programming. | Strategically chosen tachycardia detection and therapy options targeting non-sustained ventricular tachycardia (VT) or ventricular fibrillation (VF) can efficiently reduce the morbidity related to implantable cardioverter defibrillator (ICD) therapy. We report a case of a 60-year-old woman with ischemic cardiomyopathy ... |
14,847 | Cardioplegia and ventricular late potentials in cardiac surgical patients. | Ventricular late potentials (LP) recording with signal-averaged electrocar- diogram allow identifying patients at risk of sudden death and ventricular tachycardia. Cardiac surgery with cardiopulmonary bypass (CPB) could predispose to the development of myocardial ischemia related to imperfect cardioplegia. To the best ... |
14,848 | On-chip constructive cell-network study (II): on-chip quasi-in vivo cardiac toxicity assay for ventricular tachycardia/fibrillation measurement using ring-shaped closed circuit microelectrode with lined-up cardiomyocyte cell network. | Conventional in vitro approach using human ether-a-go-go related gene (hERG) assay has been considered worldwide as the first screening assay for cardiac repolarization safety. However, it does not always oredict the potential QT prolongation risk or pro-arrhythmic risk correctly. For adaptable preclinical strategiesto... |
14,849 | Impact of type 2 diabetes and the metabolic syndrome on myocardial structure and microvasculature of men with coronary artery disease. | Type 2 diabetes and the metabolic syndrome are associated with impaired diastolic function and increased heart failure risk. Animal models and autopsy studies of diabetic patients implicate myocardial fibrosis, cardiomyocyte hypertrophy, altered myocardial microvascular structure and advanced glycation end-products (AG... |
14,850 | Increased prevalence of cardiovascular risk factors in patients with acute coronary syndrome and indications for treatment with oral anticoagulation. | Antiplatelet drugs currently constitute the basic treatment of coronary artery disease (acute coronary syndrome [ACS], stable angina and patients treated with percutaneous coronary interventions [PCI]). The number of patients with indication for dual antiplatelet therapy with comorbidities with high thrombo-embolic ris... |
14,851 | Beneficial effects of terlipressin in pediatric cardiac arrest. | : Vasopressin and its analog, terlipressin (TP), are potent vasopressors that may be useful therapeutic agents in the treatment of cardiac arrest (CA), septic and catecholamine-resistant shock, and esophageal variceal hemorrhage. The American Heart Association 2000 guidelines recommend its use for adult ventricular fib... |
14,852 | Preserved heart rate variability during therapeutic hypothermia correlated to 96 hrs neurological outcomes and survival in a pig model of cardiac arrest. | Therapeutic hypothermia initiated with cardiopulmonary resuscitation improves neurologic outcomes and survival after prolonged cardiac arrest. However, the potential mechanism by which hypothermia improves neurologic outcomes remains unclear. In the current study, we investigated the effect of rapid head cooling on 96-... |
14,853 | Left atrial remodeling and response to valsartan in the prevention of recurrent atrial fibrillation: the GISSI-AF echocardiographic substudy. | Left atrial (LA) dilation precedes or appears early after the onset of atrial fibrillation (AF) and factors in perpetuating the arrhythmia. Angiotensin receptor blockers were proposed for reversing LA remodeling. We evaluated the effect of valsartan on LA remodeling in patients with a recent episode of AF and the effec... |
14,854 | Reliability of left ventricular volumes and function measurements using three-dimensional speckle tracking echocardiography. | Although the accuracy of three-dimensional speckle tracking echocardiography (STE) to quantify left ventricular (LV) volumes and function has been demonstrated, its reliability has not been studied in great detail. The aim of the study was to determine inter-observer, intra-observer, and test-retest reliability of echo... |
14,855 | Imaging cardio-vascular anatomy and function in D-Transposition of the great arteries after mustard procedure. | We used cardiovascular magnetic resonance (CMR) to demonstrate cardio-vascular anatomy and function in a 42 year-old man with a D-Transposition of the great arteries who survived a sudden cardiac arrest. |
14,856 | Human atrial action potential and Ca2+ model: sinus rhythm and chronic atrial fibrillation. | Understanding atrial fibrillation (AF) requires integrated understanding of ionic currents and Ca2+ transport in remodeled human atrium, but appropriate models are limited.</AbstractText>To study AF, we developed a new human atrial action potential (AP) model, derived from atrial experimental results and our human vent... |
14,857 | Prophylactic implantable cardioverter-defibrillator treatment in the elderly: therapy, adverse events, and survival gain. | In elderly patients, obscurity remains regarding the benefit of implantable cardioverter-defibrillator (ICD) treatment as primary prevention of sudden cardiac death. This study assesses implant rates, therapy, adverse events, and survival gain in the elderly primary prevention ICD patient.</AbstractText>A total of 1395... |
14,858 | Evolutionary innovations in cardiac pacing. | Cardiac pacing has played a significant role in mitigating morbidity and mortality associated with bradyarrhythmias. Throughout the years, advances made in battery reliability, lead performance, and device portability have rapidly expanded the use of cardiac pacemakers in many different disease states. Despite the bene... |
14,859 | Anticoagulation therapy in older adults newly diagnosed with atrial fibrillation. | Atrial fibrillation (AF) is the most common chronic arrhythmia and the most serious heart rhythm irregularity in individuals older than 70. It is usually not life threatening in and of itself, but it can lead to serious medical problems, including stroke, additional heart rhythm problems, and heart failure. Symptoms of... |
14,860 | Life-threatening atrial tachycardia after the Senning operation in a patient with transposition of the great arteries. | Atrial tachycardia (AT) is recognized as a risk factor of sudden death (SD) in patients with transposition of the great arteries (TGA) after atrial switch operation. A 20-year-old man with TGA who had undergone a Senning operation experienced a near-miss SD event 1 day after appearance of AT. He was successfully resusc... |
14,861 | Long-term cognitive outcomes following out-of-hospital cardiac arrest: a population-based study. | To report the neurologic outcomes in long-term survivors of out-of-hospital cardiac arrest with ventricular fibrillation as the presenting rhythm (OHCA VF) at a population level.</AbstractText>All adults who experienced OHCA VF in Olmsted County, MN, from 1990 to 2008, survived more than 6 months postarrest, and were a... |
14,862 | Cardiac manifestations of myotonic dystrophy type 1. | To estimate the degree of cardiac involvement regarding left ventricular ejection fraction, conduction abnormalities, arrhythmia, risk of sudden cardiac death (SCD) and the associations between cardiac involvement and cytosine-thymine-guanine (CTG)-repeat, neuromuscular involvement, age and gender in patients with myot... |
14,863 | Cardiac remodeling with rhythm versus rate control strategies for atrial fibrillation in patients with heart failure: insights from the AF-CHF echocardiographic sub-study. | In patients with heart failure and atrial fibrillation, the AF-CHF (Atrial Fibrillation and Congestive Heart Failure) trial did not demonstrate the superiority of rhythm control (RhyC) over a rate control (RaC) strategy on cardiovascular mortality. Nevertheless, deleterious hemodynamic effects of atrial fibrillation ca... |
14,864 | Suppression of ischemic and reperfusion ventricular arrhythmias by inhalational anesthetic-induced preconditioning in the rat heart. | Inhalational anesthetic-induced preconditioning (APC) has been shown to reduce infarct size and attenuate contractile dysfunction caused by myocardial ischemia. Only a few studies have reported the effects of APC on arrhythmias during myocardial ischemia-reperfusion injury, focusing exclusively on reperfusion. Accordin... |
14,865 | Distinguishing "benign" from "malignant early repolarization": the value of the ST-segment morphology. | Means for distinguishing the very common "benign early repolarization" from the very rare but malignant form are needed. Recently, the presence of early repolarization with "horizontal ST segment" was found to predict arrhythmic death during long-term follow-up in a large population study. We therefore speculated that ... |
14,866 | Inflammatory activation and carbohydrate antigen-125 levels in subjects with atrial fibrillation. | Atrial fibrillation (AF) might be associated with an inflammatory activation and reduced left ventricular (LV) function. Less is known with regard to newly introduced markers of LV dysfunction such as carbohydrate antigen-125 (CA-125) in subjects with AF. The aim of this study was therefore to assess possible associati... |
14,867 | [Totally subcutaneous cardioverter-defibrillator (S-ICD®) : recent experience and future perspectives]. | The implantable cardioverter defibrillator (ICD) is an established therapy for patients at risk of sudden cardiac death. Nevertheless the endocardial electrode in conventional systems plays a major role in long-term complications (difficult removal, risk of endocarditis, etc.). The totally subcutaneous ICD (S-ICD®... |
14,868 | [Treating congestive heart failure with cardiac contractility modulation (CCM) : possibilities and study overview]. | Cardiac contractility modulation (CCM) is a device therapy for patients with systolic heart failure. CCM therapy applies non-excitatory signals during the absolute refractory period of the heart cycle. It influences myocardial contractility by modulating the regulation of calcium cycling. CCM therapy has been proven to... |
14,869 | Recurrent torsades de pointes after catheter ablation of incessant ventricular bigeminy in combination with QT prolongation. | A 45-year-old woman, who had received a single-chamber implantable cardioverter defibrillator (ICD) due to ventricular fibrillation 5 years ago, was admitted for catheter ablation of incessant right ventricular outflow tract bigeminy. After successful ablation recurrent torsades de pointes associated with a prolonged c... |
14,870 | Association of rate-controlled persistent atrial fibrillation with clinical outcome and ventricular remodelling in recipients of cardiac resynchronization therapy. | Whether patients with persistent atrial fibrillation (AF) obtain the same degree of benefit with cardiac resynchronization therapy (CRT) as those in sinus rhythm remains unclear.</AbstractText>We enrolled 93 patients undergoing CRT implantation, 20 (22%) of whom had rate-controlled persistent AF. The primary endpoint w... |
14,871 | J-wave syndromes. from cell to bedside. | The J wave, a deflection that follows the QRS complex of the surface electrocardiogram, is usually partially buried in the R wave in humans, appearing as a J-point elevation. An early repolarization (ER) pattern characterized by J-point elevation, slurring of the terminal part of the QRS, and ST-segment elevation has l... |
14,872 | Atrial fibrillatory rate and irregularity of ventricular response as predictors of clinical outcome in patients with atrial fibrillation. | Atrial fibrillation (AF) remains the most common arrhythmia encountered in clinical practice. Electrocardiogram (ECG)-based predictors of clinical outcome, however, have mostly been studied during sinus rhythm, whereas noninvasive risk stratification of patients with AF remains largely unexplored. Advances in ECG signa... |
14,873 | Genetic suppression of atrial fibrillation using a dominant-negative ether-a-go-go-related gene mutant. | Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. Gene therapy-dependent modulation of atrial electrophysiology may provide a more specific alternative to pharmacological and ablative treatment strategies.</AbstractText>We hypothesized that genetic inactivation of atrial repolarizing ether-a-go-... |
14,874 | Increased d-dimer levels predict cardiovascular mortality in patients with systolic heart failure. | D-dimer is a fibrin degradation product, and is implicated in pathologies of cardiovascular system. Thrombosis within the vascular system in relation with inflammation and stasis might be associated with poor prognosis in patients with systolic heart failure (HF). In this study we aimed to investigate for relationship ... |
14,875 | Elevated γ-glutamyltransferase in implantable cardioverter defibrillator patients. | Elevated γ-glutamyltransferase (GGT) is a new risk factor for cardiovascular diseases, but its impact on ventricular tachyarrhythmia occurrence and survival in patients with an implantable cardioverter defibrillator (ICD) is unknown.</AbstractText>Considering that GGT levels are gender-dependent, female ICD recip... |
14,876 | Clinical characteristics of patients with atrial fibrillation at a tertiary care hospital in the central region of Saudi Arabia. | To report on the clinical presentation, etiology, and laboratory features of acute and chronic atrial fibrillation (AF) in a tertiary hospital in Riyadh, Saudi Arabia.</AbstractText>We retrospectively studied records of 720 patients with AF seen in outpatients and inpatients departments at King Abdulaziz Medical City, ... |
14,877 | Impairment of pulmonary function is an independent risk factor for atrial fibrillation: the Takahata study. | Chronic pulmonary disorders, such as chronic obstructive pulmonary disease (COPD) and fibrosing lung diseases, and atrial fibrillation (AF), are prevalent in elderly people. The impact of cardiac co-morbidities in the elderly, where pulmonary function is impaired, cannot be ignored as they influence mortality. The rela... |
14,878 | Multiple arrhythmic syndromes in a newborn, owing to a novel mutation in SCN5A. | Mutations in the SCN5A gene have been linked to Brugada syndrome (BrS), conduction disease, Long QT syndrome (LQT3), atrial fibrillation (AF), and to pre- and neonatal ventricular arrhythmias.</AbstractText>The objective of this study is to characterize a novel mutation in Na(v)1.5 found in a newborn with fetal chaotic... |
14,879 | Low safety index of domperidone: mechanism for increased odds ratio for sudden cardiac death. | Domperidone is a dopamine antagonist with anti-nausea and anti-emetic activity. There have been several reports of sudden cardiac death (SCD) associated with the compound. Recently it was estimated to increase SCD nearly fourfold. I therefore tested domperidone for liability of cardiac repolarization disturbances (tria... |
14,880 | QRS duration and QTc interval are predictors of risk for ventricular arrhythmias during cardiac resynchronization therapy. | QRS duration (QRSd) and prolonged corrected QT interval (QTc) are associated with ventricular arrhythmic events. This study was designed to determine whether CRT by means of biventricular pacing alters the QTc and QRSd, and whether such changes are related to the risk of sustained ventricular tachyarrhythmias (sVTA).</... |
14,881 | Relation of milrinone after surgery for congenital heart disease to significant postoperative tachyarrhythmias. | Milrinone reduces the risk of low cardiac output syndrome for some pediatric patients after congenital heart surgery. Data from adults undergoing cardiac surgery suggest an association between milrinone and an increased risk of postoperative arrhythmias. We tested the hypothesis that milrinone is an independent risk fa... |
14,882 | Clinical and echocardiographic predictors of outcomes in patients with apical hypertrophic cardiomyopathy. | Apical hypertrophic cardiomyopathy (HC) is considered to have a favorable prognosis, but recent observations have suggested less benign clinical courses. We investigated the outcomes in patients with apical HC and evaluated the predictors. All 454 patients with apical HC (316 men, age 61 ± 11 years) were recruited... |
14,883 | Rate and irregularity of electrical activation during atrial fibrillation affect myocardial NGF expression via different signalling routes. | An irregular ventricular response during atrial fibrillation (AF) has been shown to mediate an increase in sympathetic nerve activity in human subjects. The molecular mechanisms remain unclear. This study aimed to investigate the impact of rate and irregularity on nerve growth factor (NGF) expression in cardiomyocytes,... |
14,884 | 'Cooling and cathing' the post-resuscitated. | Cronier and co-workers provide additional evidence that routine use of mild therapeutic hypothermia combined with emergent coronary angiography and percutaneous intervention results in excellent survival with intact neurological function for post-resuscitation patients with ventricular fibrillation. |
14,885 | Decadal electrocardiographic changes between age 40 and 50 in military pilots. | Cardiovascular diseases can lead to sudden in-flight incapacitation and long-term disability in aircraft pilots. Electrocardiogram (ECG) has been widely used to screen for these diseases in routine aeromedical examinations. Several ECG changes such as complete left bundle-branch block (CLBBB) and left ventricular hyper... |
14,886 | Comparison of ventricular tachyarrhythmia characteristics in patients with idiopathic dilated or ischemic cardiomyopathy and defibrillators implanted for primary prevention. | Implantable cardioverter-defibrillator (ICD) therapy for primary prevention is well established in ischemic cardiomyopathy (ICM). Data on the role of ICDs in patients with dilated cardiomyopathy (DCM) and no history of ventricular tachyarrhythmia (VT/VF) are more limited.</AbstractText>DCM patients with an impaired lef... |
14,887 | Severe hypothermia in a patient with spinal cord injury without radiological abnormality. | We report a case of a 64-year-old caucasian male who was transported to the emergency department (ED) after being found unconscious on the side of the road. On arrival to the ED the patient went into ventricular fibrillation and advanced cardiac life support was started at that time. Thirty minutes into the resuscitati... |
14,888 | Hypokalemic quadriparesis in Sjogren syndrome. | We report a 58-year-old woman who presented with acute quadriparesis, bulbar weakness, atrial fibrillation, ventricular ectopics, and distal renal tubular acidosis with severe hypokalemia. She recovered completely on potassium and alkali supplementation. The patient also had hypergammaglobulinemia with probable primary... |
14,889 | Effect of hepatitis C virus infection on the left ventricular systolic and diastolic functions. | Hepatitis secondary to infection with the hepatitis C virus (HCV) is one of the most common causes of viral hepatitis worldwide. Multiple extrahepatic manifestations of HCV infection have been recognized. Dilated and hypertrophic cardiomyopathy associated with HCV infection have been recently described in the literatur... |
14,890 | [How beta-blockers are used in Spain? Analysis of limitations in their use in internal medicine and cardiology: CARACTER-BETA study]. | Beta-blocker treatment has a class I indication, level of evidence A, in guidelines for the treatment of heart failure, ischemic heart disease, and atrial fibrillation. However, beta-blocker use continues to be less than optimal. In this study, beta blocker use in Spain is analyzed in patients with heart failure, ische... |
14,891 | Invasive acute hemodynamic response to guide left ventricular lead implantation predicts chronic remodeling in patients undergoing cardiac resynchronization therapy. | We evaluated the relationship between acute hemodynamic response (AHR) and reverse remodeling (RR) in cardiac resynchronization therapy (CRT).</AbstractText>CRT reduces mortality and morbidity in heart failure patients; however, up to 30% of patients do not derive symptomatic benefit. Higher proportions do not remodel.... |
14,892 | Atrial-selective inhibition of sodium-channel current by Wenxin Keli is effective in suppressing atrial fibrillation. | Wenxin Keli is a Chinese herb extract reported to be of benefit in the treatment of cardiac arrhythmias, cardiac inflammation, and heart failure.</AbstractText>We evaluated the electrophysiologic effects of Wenxin Keli in isolated canine arterially perfused right atrial preparations with a rim of right ventricular tiss... |
14,893 | Efficacy of a new accelerated streptokinase regime in acute myocardial infarction: a double blind randomized clinical trial. | Studies of thrombolysis in acute ST-elevation myocardial infarction (STEMI) have focused on differences in outcome between groups receiving various regimes. Expedited treatment may influence the efficacy of nonfibrin specific thrombolytic agents in restoring early patency of the infarct-related artery (IRA), which is a... |
14,894 | Resuscitation strategies from bupivacaine-induced cardiac arrest. | Local anesthetic (LA) intoxication with cardiovascular arrest is a potential fatal complication of regional anesthesia. Lipid resuscitation has been recommended for the treatment of LA-induced cardiac arrest. Aim of the study was to compare four different rescue regimens using epinephrine and/or lipid emulsion and vaso... |
14,895 | Predictors and course of high-degree atrioventricular block after transcatheter aortic valve implantation using the CoreValve Revalving System. | Transcatheter aortic valve implantation (TAVI) is a novel treatment for high risk or inoperable patients with symptomatic severe aortic stenosis. However, significant atrioventricular (AV) conduction system abnormalities requiring permanent pacemaker (PPM) implantation might complicate this procedure. We used best subs... |
14,896 | Does rheumatic valvular heart disease affect right ventricular performance? | Right ventricular (RV) function often determines clinical outcome in patients with valvular heart disease. Though difficult to assess by echocardiography, Tei index is useful in its assessment. The aims of the study were to evaluate global RV function using the Tei index in patients with rheumatic heart disease and to ... |
14,897 | Defibrillation. | Defibrillation may be needed in witnessed and unwitnessed cardiac arrests. Cardiopulmonary resuscitation (CPR) must be initiated and defibrillation administered without delay. Every shock cycle includes 1-2 minutes of CPR followed by rhythm analysis. The energy level for biphasic defibrillation of ventricular fibrillat... |
14,898 | When, where and how to initiate hypothermia after adult cardiac arrest. | Therapeutich hypothermia (TH) has been shown to improve neurological outcome and survival after witnessed cardiac arrest (CA) that is due to ventricular fibrillation. Although TH is widely used following witnessed CA as well as all forms of initial rhythm, the mortality rate after CA remains unacceptably high, and addi... |
14,899 | An atrioventricular node model for analysis of the ventricular response during atrial fibrillation. | This paper introduces a model of the atrioventricular node function during atrial fibrillation (AF), and describes the related ECG-based estimation method. The proposed model is defined by parameters that characterize the arrival rate of atrial impulses, the probability of an impulse choosing either one of the two atri... |
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