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15,000 | The role of photon scattering in voltage-calcium fluorescent recordings of ventricular fibrillation. | Recent optical mapping studies of cardiac tissue suggest that membrane voltage (V(m)) and intracellular calcium concentrations (Ca) become dissociated during ventricular fibrillation (VF), generating a proarrhythmic substrate. However, experimental methods used in these studies may accentuate measured dissociation due ... |
15,001 | Outpatient approach to palpitations. | Palpitations are a common problem seen in family medicine; most are of cardiac origin, although an underlying psychiatric disorder, such as anxiety, is also common. Even if a psychiatric comorbidity does exist, it should not be assumed that palpitations are of a noncardiac etiology. Discerning cardiac from noncardiac c... |
15,002 | Effects of the novel amiodarone-like compound SAR114646A on cardiac ion channels and ventricular arrhythmias in rats. | Amiodarone is the "gold standard" for current antiarrhythmic therapy because it combines efficacy with good hemodynamic and electrophysiological tolerance. Amiodarone is effective against both atrial and ventricular arrhythmias by intravenous (i.v.) or oral route. However, the i.v. formulation has limitations. Therefor... |
15,003 | Aortic bifurcation rupture after blunt abdominal trauma in a child: a case report. | Blunt trauma to the abdomen resulting in aortic injury is rare in children with only a few case reports in the past 40 years. We describe the diagnosis and management of a 2-year-old boy who survived an aortic bifurcation rupture after blunt trauma. |
15,004 | Global epidemiology and demographics of commotio cordis. | The commotio cordis literature has largely focused on events occurring in the United States. However, with enhanced public awareness, commotio cordis has been increasingly recognized internationally as a cause of cardiac arrest and sudden death due to blunt nonpenetrating chest blows.</AbstractText>This study sought to... |
15,005 | The impact of increased chest compression fraction on return of spontaneous circulation for out-of-hospital cardiac arrest patients not in ventricular fibrillation. | Greater chest compression fraction (CCF, or proportion of CPR time spent providing compressions) is associated with better survival for out-of-hospital cardiac arrest (OOHCA) patients in ventricular fibrillation (VF). We evaluated the effect of CCF on return of spontaneous circulation (ROSC) in OOHCA patients with non-... |
15,006 | The prevalence and the prognostic value of microvolt T-wave alternans in patients with hypertrophic cardiomyopathy. | Nonsustained ventricular tachycardia (nVT) may have ominous implications for patients with hypertrophic cardiomyopathy (HCM). The microvolt T-wave alternans (TWA) has been proposed as a noninvasive tool-identifying patients at risk of sudden cardiac death and ventricular tachycardia/fibrillation (VT/VF). The aim of the... |
15,007 | Usefulness of acute delirium as a predictor of adverse outcomes in patients >65 years of age with acute decompensated heart failure. | Delirium is an acute confusional state that is very prevalent in older patients hospitalized with acute decompensated heart failure (ADHF). The association between delirium and ADHF outcome has not been well described. We analyzed 883 consecutive patients >65 years of age admitted with ADHF. Acute delirium was diagn... |
15,008 | [The driver's illness as a cause of traffic accidents]. | Fatal motor vehicle accidents (fMVAs) as well as accidents involving pedestrians or bicyclists in Uusimaa county in 2008 were reviewed. Of the fMVAs, acute disease attacks while driving caused 26.5% (9/34) of the drivers' deaths. This equalled with the number of alcohol-related fatal accidents. Heart attack was the mai... |
15,009 | Ablation of Atrial Fibrillation in the Elderly: Current Evidence and Evolving Trends. | Management of atrial fibrillation in the elderly presents unique challenges, including deciding upon the best treatment strategy: rate control versus rhythm control. The decision to pursue one treatment strategy over another is based on understanding the underlying disorder: symptomatology from atrial fibrillation itse... |
15,010 | Left ventricular hypertrophy: major risk factor in patients with hypertension: update and practical clinical applications. | Left ventricular hypertrophy is a maladaptive response to chronic pressure overload and an important risk factor for atrial fibrillation, diastolic heart failure, systolic heart failure, and sudden death in patients with hypertension. Since not all patients with hypertension develop left ventricular hypertrophy, there ... |
15,011 | Low-energy control of electrical turbulence in the heart. | Controlling the complex spatio-temporal dynamics underlying life-threatening cardiac arrhythmias such as fibrillation is extremely difficult, because of the nonlinear interaction of excitation waves in a heterogeneous anatomical substrate. In the absence of a better strategy, strong, globally resetting electrical shock... |
15,012 | Atrial selective effects of intravenously administered vernakalant in conscious beagle dogs. | Vernakalant is a relatively atrial-selective antiarrhythmic drug approved for the conversion of recent onset atrial fibrillation in Europe and is under regulatory review in the United States. In this study, we examined the effects of intravenously administered vernakalant (5, 10, and 20 mg/kg) on blood pressure, heart ... |
15,013 | Outcomes of cardiac perforation complicating catheter ablation of ventricular arrhythmias. | Cardiac perforation is a recognized complication of catheter ablation procedures, most commonly encountered during ablation of atrial fibrillation. The study aims to investigate the incidence, management, and hospital outcomes of cardiac perforation complicating catheter ablation for ventricular arrhythmias.</AbstractT... |
15,014 | Asymmetric dimethylarginine predicts appropriate implantable cardioverter-defibrillator intervention in patients with left ventricular dysfunction. | More precise characterization of risk factors for occurring ventricular arrhythmia in patients (pts) with primary prevention implantable cardioverter-defibrillator (ICD) therapy is critical. We sought to investigate whether biomarkers of nitric oxide metabolism can predict the occurrence of ventricular tachyarrhythmias... |
15,015 | Live 3D TEE demonstrates and guides the management of prosthetic mitral valve obstruction. | A 43-year-old woman, with a remote history of rheumatic mitral stenosis and a St. Jude prosthetic mitral valve replacement, presented with shortness of breath and palpitations, shortly after a long flight. On admission, atrial fibrillation with a rapid ventricular response was noted in the setting of a long history of ... |
15,016 | Intramural activation during early human ventricular fibrillation. | We investigated patterns of intramural activation in early human ventricular fibrillation (VF) and hypothesized that intramural reentry colocalizes to sites with increased intramural fibrosis.</AbstractText>Thirteen human Langendorff hearts were used for this study. Twenty-five plunge needles (4 unipoles/needle) were u... |
15,017 | [Effects of Chinese herbal medicines Shengmai injection and Xuesaitong injection on ventricular fibrillation threshold and connexin 43 expression in rats with myocardial infarction]. | To explore the effects of Shengmai injection and Xuesaitong injection, compound Chinese herbal medicines for replenishing qi and activating blood, on ventricular fibrillation threshold, heart structure and connexin 43 (Cx43) expression in rats with myocardial infarction (MI).</AbstractText>One hundred male SD rats were... |
15,018 | Plitidepsin has a safe cardiac profile: a comprehensive analysis. | Plitidepsin is a cyclic depsipeptide of marine origin in clinical development in cancer patients. Previously, some depsipeptides have been linked to increased cardiac toxicity. Clinical databases were searched for cardiac adverse events (CAEs) that occurred in clinical trials with the single-agent plitidepsin. Demograp... |
15,019 | Arrhythmias in the coronary care unit. | Symptomatic sustained cardiac arrhythmias are frequently observed in in the coronary care unit and often lead to hemodynamic compromise, especially in the presence of multisystem disease. The predominant arrhythmias noted in intensive care units are tachyarrhythmias, particularly atrial fibrillation and flutter, and ve... |
15,020 | Therapeutic hypothermia after out-of-hospital cardiac arrest: evaluation of a regional system to increase access to cooling. | Therapeutic hypothermia (TH) improves survival and confers neuroprotection in out-of-hospital cardiac arrest (OHCA), but TH is underutilized, and regional systems of care for OHCA that include TH are needed.</AbstractText>The Cool It protocol has established TH as the standard of care for OHCA across a regional network... |
15,021 | Success of ablation for atrial fibrillation in isolated left ventricular diastolic dysfunction: a comparison to systolic dysfunction and normal ventricular function. | The efficacy of radiofrequency ablation for atrial fibrillation (AF) in patients with left ventricular (LV) systolic dysfunction and isolated diastolic dysfunction is uncertain.</AbstractText>A prospective cohort of patients with normal and abnormal LV function underwent ablation for antiarrhythmic drug (AAD)-refractor... |
15,022 | An unfortunate case of Pendred syndrome. | To report a patient with Pendred syndrome who developed life-threatening hypokalaemia as an unpredicted consequence of implant-induced imbalance and alcohol dependency, leading to multiple cardiac arrests.</AbstractText>Addenbrooke's Hospital, Cambridge, UK.</AbstractText>Case report and review of the English language ... |
15,023 | Fluoroscopic left ventricular lead position and the long-term clinical outcome of cardiac resynchronization therapy. | To determine the effects of left ventricular (LV) lead tip position on the long-term outcome of cardiac resynchronization therapy (CRT).</AbstractText>Cardiac device therapy center.</AbstractText>Five hundred and fifty-six patients (age 70.4 ± 10.7 years [mean ± standard deviation]).</AbstractText>CRT-pacing ... |
15,024 | Syncope during exercise: just another benign vasovagal event? | In general, syncope in children and adolescents is a benign event. Syncope during exercise may identify patients with a potentially fatal condition. Catecholaminergic polymorphic ventricular tachycardia is characterized by life-threatening ventricular arrhythmias, usually polymorphic ventricular tachycardia or ventricu... |
15,025 | Atrial fibrillation and mortality in African American patients with heart failure: results from the African American Heart Failure Trial (A-HeFT). | Atrial fibrillation (AF) is common in patients with heart failure (HF) and portends a worsened prognosis. Because of the low enrollment of African American subjects (AAs) in randomized HF trials, there are little data on AF in AAs with HF. This post hoc analysis reviews characteristics and outcomes of AA patients with ... |
15,026 | Experiment-model interaction for analysis of epicardial activation during human ventricular fibrillation with global myocardial ischaemia. | We describe a combined experiment-modelling framework to investigate the effects of ischaemia on the organisation of ventricular fibrillation in the human heart. In a series of experimental studies epicardial activity was recorded from 10 patients undergoing routine cardiac surgery. Ventricular fibrillation was induced... |
15,027 | Clinical study of the electrophysiological effects of ischemic post-conditioning in patients with acute myocardial infarctions. | Ischemic "pre"-conditioning has been shown to have antiarrhythmic effects. The aim of this study was to investigate whether ischemic "post"-conditioning (post-CON) also has antiarrhythmic effects in ST-segment elevation myocardial infarction (STEMI) patients undergoing coronary angioplasty (PCI) as a clinical model of ... |
15,028 | Ranolazine reduces Ca2+ overload and oxidative stress and improves mitochondrial integrity to protect against ischemia reperfusion injury in isolated hearts. | Ranolazine is a clinically approved drug for treating cardiac ventricular dysrhythmias and angina. Its mechanism(s) of protection is not clearly understood but evidence points to blocking the late Na+ current that arises during ischemia, blocking mitochondrial complex I activity, or modulating mitochondrial metabolism.... |
15,029 | Autoantibodies and cardiac arrhythmias. | Autoimmune diseases are associated with significant morbidity and mortality, afflicting about 5% of the US population. They encompass a wide range of disorders that affect all organs of the human body and have a predilection for women. In the past, autoimmune pathogenesis was not thought to be a major mechanism for car... |
15,030 | Ischemic ventricular arrhythmias: experimental models and their clinical relevance. | In the United States, sudden cardiac death accounts for an estimated 300,000 to 350,000 cases each year, with 80,000 presenting as the first manifestation of a preexisting, sometimes unrecognized, coronary artery disease. Acute myocardial infarction (AMI)-induced ventricular fibrillation frequently occurs without warni... |
15,031 | Can death unrelated to secondary causes be predicted in intubated comatose tricyclic antidepressant-poisoned patients? | It has been stated that the level of consciousness at presentation is the most sensitive clinical predictor of dysrhythmia and seizure in patients with tricyclic antidepressant (TCA) overdose.</AbstractText>To assess the prognostic value of the clinical characteristics and electrocardiographic (ECG) parameters in intub... |
15,032 | Effects of quinidine on the action potential duration restitution property in the right ventricular outflow tract in patients with brugada syndrome. | On a cellular level, Brugada syndrome has been attributed to a deep phase 1 notch and subsequent shallow and prolonged repolarization in the right ventricular outflow tract (RVOT). A sodium channel mutation that leads to early inactivation of the late sodium current has been identified in some patients. Thus, drugs tha... |
15,033 | Prevalence of J-point elevation in sudden arrhythmic death syndrome families. | The purpose of this study was to assess the prevalence of J-point elevation among the relatives of sudden arrhythmic death syndrome (SADS) probands.</AbstractText>J-point elevation is now known to be associated with idiopathic ventricular fibrillation. We hypothesized that this early repolarization phenomenon is an inh... |
15,034 | Atrial electrical and structural changes associated with longstanding hypertension in humans: implications for the substrate for atrial fibrillation. |  </AbstractText>Hypertension (HT) is the most common modifiable risk factor for atrial fibrillation (AF), yet little is known of the atrial effects of chronic HT in humans. We aimed to characterize the electrophysiologic (EP) and electroanatomic (EA) remodeling of the right atrium (RA) in patients with chronical... |
15,035 | Outcomes of cardiac catheterization and percutaneous coronary intervention for in-hospital ventricular tachycardia or fibrillation cardiac arrest. | This study examined outcomes of patients with sudden cardiac death attributable to primary ventricular tachycardia (VT) or ventricular fibrillation (VF) that underwent cardiac catheterization with or without percutaneous coronary intervention (PCI).</AbstractText>The decision to perform cardiac catheterization and PCI ... |
15,036 | Atrial ectopic tachycardia in a patient with marfan syndrome. | The fibrillin defect central to Marfan syndrome is believed to affect myocardial conduction and predispose affected patients to various arrhythmias, including ventricular tachycardia, atrial fibrillation, and atrioventricular nodal reentry tachycardia. Here we describe an adult Marfan patient with atrial ectopic tachyc... |
15,037 | The phosphatonin fibroblast growth factor 23 links calcium-phosphate metabolism with left-ventricular dysfunction and atrial fibrillation. | High serum phosphate is linked to cardiovascular morbidity and mortality in the general population. Fibroblast growth factor 23 (FGF-23) is a critical phosphate regulating hormone, potentially reflecting phosphate load better than a single serum phosphate measurement. Recent pioneering echocardiographic studies associa... |
15,038 | Assessment of sotalol prescribing in a community hospital: opportunities for clinical pharmacist involvement. | Due to risk of serious adverse drug events (ADEs) sotalol use is limited in renal insufficiency and heart failure. To reduce potential life-threatening ADEs, medication safety initiatives that ensure appropriate dosing of sotalol are necessary. Pharmacist-managed renal dosing assessment programmes ensure appropriate do... |
15,039 | Angiotensin II does not acutely regulate conduction velocity in rat atrial tissue. | Atrial angiotensin II (Ang II) levels are increased in atrial fibrillation and are believed to be important in the pathogenesis of atrial arrhythmias. Ang II reduces intercellular coupling by inhibiting gap junctions (connexins) and may thereby increase the risk of reentry arrhythmia. The aim of the current study was t... |
15,040 | The value of a family history of sudden death in patients with diagnostic type I Brugada ECG pattern. | We sought to investigate the value of a family history of sudden death (SD) in Brugada syndrome (BS).</AbstractText>Two hundred and eighty consecutive patients (mean age: 41 ± 18 years, 168 males) with diagnostic type I Brugada ECG pattern were included. Sudden death occurred in 69 (43%) of 157 families. One hundr... |
15,041 | The impact of body mass index on the efficacy and safety of catheter ablation of atrial fibrillation. | Obesity is a well established risk factor for atrial fibrillation (AF) development. Our purpose was to determine the impact of body mass index (BMI) on the safety and efficacy of radiofrequency catheter ablation of AF.</AbstractText>Two hundred and twenty-six consecutive patients with symptomatic, drug-refractory parox... |
15,042 | Biomarkers of structural remodelling and endothelial dysfunction for prediction of cardiovascular events or death in patients with atrial fibrillation. | Atrial fibrillation (AF) is associated not only with inflammation but also with structural remodelling and altered endothelial activation which may contribute to clot formation, embolization and mortality. We aimed to determine the predictive value of single-time biomarker analysis for prediction of outcome in patients... |
15,043 | Sodium nitroprusside-enhanced cardiopulmonary resuscitation improves resuscitation rates after prolonged untreated cardiac arrest in two porcine models. | Sodium nitroprusside-enhanced cardiopulmonary resuscitation consists of active compression-decompression, an impedance threshold device, abdominal binding, and large intravenous doses of sodium nitroprusside. We hypothesize that sodium nitroprusside-enhanced cardiopulmonary resuscitation will significantly increase car... |
15,044 | Hypothermia after cardiac arrest: beneficial, but slow to be adopted. | Survivors of cardiac arrest due to ventricular tachycardia or ventricular fibrillation have improved neurologic outcomes if they are cooled to a core body temperature of 32°C to 34°C for 24 hours as soon as possible after reaching the hospital. |
15,045 | Update in hospital medicine: studies likely to affect inpatient practice in 2011. | Dabigatran (Pradaxa) will likely start to replace warfarin (Coumadin) both to prevent stroke in patients with atrial fibrillation and to prevent recurrent venous thromboembolism. Using a checklist during insertion of central venous catheters can decrease the rate of catheter-related bloodstream infections in the intens... |
15,046 | Remodeling of atrial ATP-sensitive K⁺ channels in a model of salt-induced elevated blood pressure. | Hypertension is associated with the development of atrial fibrillation; however, the electrophysiological consequences of this condition remain poorly understood. ATP-sensitive K(+) (K(ATP)) channels, which contribute to ventricular arrhythmias, are also expressed in the atria. We hypothesized that salt-induced elevate... |
15,047 | Left atrial 'sludge' during vagally mediated pause triggered by pulmonary vein antral ablation. | We report a case of a patient with long-standing persistent atrial fibrillation (AF) who had rapid formation of spontaneous echo-contrast in the left atrium during pulmonary vein antrum isolation set off by a vagally mediated pause despite standard anticoagulation protocol. Spontaneous echo contrast resolved with ventr... |
15,048 | Safety of nerve conduction studies in patients with implantable cardioverter-defibrillators. | A patient with an implantable cardioverter-defibrillator (ICD) may suffer from neuromuscular disorders and may need to undergo a nerve conduction study (NCS). However, a NCS may be a source of electromagnetic interference (EMI). The aim of the present study was to investigate whether the interference from NCS used in a... |
15,049 | Usefulness of left ventricular diastolic dysfunction assessed by pulsed tissue Doppler imaging as a predictor of atrial fibrillation recurrence after successful electrical cardioversion. | The impact of left ventricular (LV) diastolic dysfunction on risk of atrial fibrillation (AF) recurrence is still unknown. The aim of this study was to assess the role of LV diastolic dysfunction in predicting AF recurrence after successful electrical cardioversion in patients with nonvalvular AF. In 51 patients with a... |
15,050 | The effect of heart rhythm on patient radiation dose with dual-source cardiac computed tomography. | To lower the radiation exposure associated with cardiac CT, it is essential to identify all factors that influence radiation dose.</AbstractText>We explored the effect of heart rhythm during scan acquisition on radiation dose with a 64-slice dual-source cardiac CT.</AbstractText>Patient and scan data were collected pro... |
15,051 | High-frequency powers hidden within QRS complex as an additional predictor of lethal ventricular arrhythmias to ventricular late potential in post-myocardial infarction patients. | Ventricular late potentials (VLPs) have been known to be a predictor of lethal ventricular arrhythmias (L-VAs); however, detection of other arrhythmogenic signals within the QRS complex remains obscure.</AbstractText>The aim of this study was to evaluate whether abnormal intra-QRS high-frequency powers (IQHFP) within t... |
15,052 | Double-valve Libman-Sacks endocarditis causing ventricular fibrillation cardiac arrest. | Libman-Sacks endocarditis is a well-known and rather common cardiac manifestation of systemic lupus erythematosus. Transesophageal and transthoracic echocardiography are the definitive imaging methods used to evaluate cardiac valvular involvement in this disease. Valvular masses (vegetations) and valvular thickening ar... |
15,053 | In-treatment stroke volume predicts cardiovascular risk in hypertension. | To evaluate whether lower stroke volume during antihypertensive treatment is a predictor of cardiovascular events independent of left ventricular geometric pattern.</AbstractText>The association between left ventricular stroke volume and combined cardiovascular death, stroke and myocardial infarction, the prespecified ... |
15,054 | Clinical characteristics and cardiovascular outcomes of hemodialysis patients with atrial fibrillation: a prospective follow-up study. | <AbstractText Label="BACKGROUND/AIMS" NlmCategory="OBJECTIVE">Among the cardiovascular complications in dialysis patients, atrial fibrillation (AF) is the most common arrhythmia. The purpose of this study was to clarify the characteristics and mortality of hemodialysis patients with AF, which are not completely elucida... |
15,055 | Holter monitoring in syncope: diagnostic yield in octogenarians. | To determine the diagnostic yield of Holter monitoring in very old adults (≥80) with syncope.</AbstractText>A Holter study was considered diagnostic if the arrhythmia explained syncope (atrioventricular (AV) block, sinus node dysfunction, atrial fibrillation with severe bradycardia or tachycardia, supraventricul... |
15,056 | Cerebral air emboli with atrial-esophageal fistula following atrial fibrillation ablation: a case report and review. | Atrial-esophageal fistula (AEF) is a rare and early complication of radiofrequency ablation for medically refractory atrial fibrillation, but has devastating consequences when the diagnosis is delayed or difficult to make.</AbstractText>Single case in a neurosciences critical care center.</AbstractText>A 69-year-old ma... |
15,057 | Cardioprotective activity of alcoholic extract of Tinospora cordifolia (Willd.) Miers in calcium chloride-induced cardiac arrhythmia in rats. | The present study investigated the antiarrhythmic activity of alcoholic extract of Tinospora cordifolia (T. cordifolia) in CaCl2 induced arrhythmia. CaCl2 (25 mg/kg) was administered by intravenous infusion (iv) to produce arrhythmia in rats. The animals were then treated with T. cordifolia extract (150, 250, and 450 m... |
15,058 | Increase in survival and bystander CPR in out-of-hospital shockable arrhythmia: bystander CPR and female gender are predictors of improved outcome. Experiences from Sweden in an 18-year perspective. | In a national perspective, to describe survival among patients found in ventricular fibrillation or pulseless ventricular tachycardia witnessed by a bystander and with a presumed cardiac aetiology and answer two principal questions: (1) what are the changes over time? and (2) which are the factors of importance?</Abstr... |
15,059 | Survival does not improve when therapeutic hypothermia is added to post-cardiac arrest care. | We investigated whether the use of therapeutic hypothermia improves the outcome after cardiac arrest (CA) under routine clinical conditions.</AbstractText>In a retrospective study, data of CA survivors treated from 2003 to 2010 were analysed. Of these, 143 patients were treated with hypothermia at 33 ± 0.5°C ... |
15,060 | Beta-blocker therapy for valvular disorders. | Valvular disorders are common, and result in a neurohormonal milieu similar to the heart failure state. Although valve surgery is the therapy of choice in symptomatic severe lesions, many patients do not receive surgery for a variety of reasons. Beta-blockers have a role in the management of many patients with valvular... |
15,061 | Impact of left ventricular ejection fraction on occurrence of ventricular events in defibrillator patients with coronary artery disease. | Primary preventive implantable cardioverter defibrillator (ICD) therapy is indicated in patients with coronary artery disease (CAD) and left ventricular ejection fraction (LVEF) of ≤ 35%, but some patients in the major trials had LVEF in the range of 30-35%. We hypothesized that these patients constitute a lower... |
15,062 | Right ventricular lead positioning does not influence the benefits of cardiac resynchronization therapy in patients with heart failure and atrial fibrillation. | Little is known about the optimal right ventricular (RV) pacing site in cardiac resynchronization therapy (CRT). This study compares bi-ventricular pacing at the left ventricular (LV) free wall combined with two different RV stimulation sites: RV outflow tract (RVOT+LV) vs. RV-apex (RVA+LV).</AbstractText>Thirty-three ... |
15,063 | [Case of ventricular fibrillation in patients with brugada type electrocardiogram during surgery]. | We described a case of ventricular fibrillation in patients with Brugada type electrocardiogram (ECG) during surgery. A 63-year-old man underwent lung lobectomy under combined general and epidural anesthesia. His preoperative ECG showed Brugada type, but he was asymptomatic and did not have a family history of sudden d... |
15,064 | [Case of coronary vasospasm during lumbar discectomy in prone position]. | A 62-year-old man with hypertension was scheduled for discectomy at L4-5 in prone position. Anesthesia was induced with propofol 70 mg, fentanyl 0.75 mg and rocuronium 40 mg and maintained with sevoflurane 0.8-2.0% in oxygen 2 l x min(-1) and nitrous oxide 2 l x min(-1). Just before the end of surgery, ST elevation wit... |
15,065 | Electrocardiographic changes in hospitalized patients with leptospirosis over a 10-year period. | The aim of this study was to investigate the incidence and type of ECG changes in patients with leptospirosis regardless of clinical evidence of cardiac involvement.</AbstractText><AbstractText Label="MATERIAL/METHODS" NlmCategory="METHODS">A total of 97 patients with serologically confirmed leptospirosis treated at th... |
15,066 | The effects of acute amiodarone on short- and long-duration ventricular defibrillation threshold in canines. | Some studies have shown that the defibrillation threshold (DFT) differs between short-duration ventricular fibrillation (SDVF, <1 minute) and long-duration ventricular fibrillation (LDVF > 1 minute). The goal of this study is to evaluate the effects of acute intravenous amiodarone on SDVF-DFT and LDVF-DFT and its... |
15,067 | Cholecystokinin octapeptide induces hypothermia and improves outcomes in a rat model of cardiopulmonary resuscitation. | To investigate the effects of cholecystokinin octapeptide on thermoregulation, postresuscitation myocardial function, neurologic outcome, and duration of survival in a rat model of cardiopulmonary resuscitation.</AbstractText>: Prospective, randomized, placebo-controlled experimental study.</AbstractText>University-aff... |
15,068 | Mild therapeutic hypothermia is associated with favourable outcome in patients after cardiac arrest with non-shockable rhythms. | Mild therapeutic hypothermia (32-34°C) improves neurological recovery and reduces the risk of death in comatose survivors of cardiac arrest when the initial rhythm is ventricular fibrillation or pulseless ventricular tachycardia. The aim of the presented study was to investigate the effect of mild therapeutic hypo... |
15,069 | The prevalence of early repolarization in Wolff-Parkinson-White syndrome with a special reference to J waves and the effects of catheter ablation. | We determined the prevalence of J waves in the electrocardiograms (ECG) of 120 patients with Wolff-Parkinson-White syndrome in comparison with J-wave prevalence in a control group of 1936 men and women with comparable demographic and ECG characteristics and with normal atrioventricular conduction. J waves were present ... |
15,070 | Tissue Doppler atrial conduction times and electrocardiogram interlead P-wave durations with varying severity of obstructive sleep apnea. | Obstructive sleep apnea (OSA) has been reported to be associated with an increased risk of atrial fibrillation. The aim of this study was to investigate atrial electromechanical couplings in patients with OSA and the relationship between these parameters and P-wave dispersion (Pd).</AbstractText>One hundred twenty-six ... |
15,071 | Heart failure with recovered ejection fraction: a distinct clinical entity. | A subset of patients with heart failure (HF) and preserved left ventricular ejection fraction (EF) previously had EF <40%. We postulated that such "recovered" EF patients would be prevalent in a referral HF population and clinically distinct from those with persistently preserved or reduced EF.</AbstractText>We iden... |
15,072 | Reconstituted high-density lipoprotein shortens cardiac repolarization. | We hypothesize that increasing high-density lipoprotein cholesterol (HDL-C) shortens cardiac repolarization.</AbstractText>HDL-C is inversely associated with sudden death. The relation between HDL-C and repolarization of the heart is unexplored.</AbstractText>HDL-C was elevated with reconstituted high-density lipoprote... |
15,073 | Incidence and predictors of major complications from contemporary catheter ablation to treat cardiac arrhythmias. | Updated understanding of the risks of catheter ablation is important because techniques have evolved for procedures treating non-life-threatening as well as potentially lethal arrhythmias.</AbstractText>This prospective study sought to assess the incidence and predictors of major complications from contemporary cathete... |
15,074 | Postpacing abnormal repolarization in catecholaminergic polymorphic ventricular tachycardia associated with a mutation in the cardiac ryanodine receptor gene. | Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an arrhythmogenic disease for which electrophysiological studies (EPS) have shown to be of limited value.</AbstractText>This study presents a CPVT family in which marked postpacing repolarization abnormalities during EPS were the only consistent phenotypic... |
15,075 | Reduced diameter spheres increases the risk of chest blow-induced ventricular fibrillation (commotio cordis). | Sudden death due to low-energy blunt trauma to the precordium (commotio cordis) has been described with a variety of sporting objects. However, the risk of ventricular fibrillation (VF) relative to the shape of the impact object is not known.</AbstractText>The objective of the current experiment is to test whether the ... |
15,076 | Protein kinase C downregulates I(Ks) by stimulating KCNQ1-KCNE1 potassium channel endocytosis. | The slow-activating cardiac repolarization K(+) current (I(Ks)), generated by the KCNQ1-KCNE1 potassium channel complex, is controlled via sympathetic and parasympathetic regulation in vivo. Inherited KCNQ1 and KCNE1 mutations predispose to ventricular fibrillation and sudden death, often triggered by exercise or emoti... |
15,077 | Short-term variability of repolarization predicts ventricular tachycardia and sudden cardiac death in patients with structural heart disease: a comparison with QT variability index. | Monitoring arrhythmic risk may improve management of patients with implantable cardioverter-defibrillators (ICD) and prevent ICD shocks. Changes in repolarization duration between subsequent beats quantified as short-term variability (STV) is associated with ventricular arrhythmias in several animal models.</AbstractTe... |
15,078 | Cardiac resynchronization therapy and the relationship of percent biventricular pacing to symptoms and survival. | With the advent of cardiac resynchronization therapy, it was unclear what percentage of biventricular pacing would be required to obtain maximal symptomatic and mortality benefit from the therapy. The optimal percentage of biventricular pacing and the association between the amount of continuous pacing and survival is ... |
15,079 | Anesthetic management of patients with Brugada syndrome: a case series and literature review. | To review the anesthetic management and perioperative outcomes of patients diagnosed with Brugada syndrome (BrS) who were treated at a single centre and to compare those results with a comprehensive review of the existing literature.</AbstractText>A retrospective chart review of anesthesia records from patients diagnos... |
15,080 | Ventricular fibrillation after exposure to air freshener-death just a breath away. | A case of ventricular fibrillation due to butane toxicity after unintentional inhalation of air freshener is reported for its rarity and to create awareness among practitioners and the public. A 25-year-old woman collapsed in the supermarket after unintended exposure to air freshener sprayed into her nostrils. Her husb... |
15,081 | Left ventricular noncompaction syndrome masquerading or misdiagnosed as congenital long QT syndrome: remember QT prolongation does not equal long QT syndrome. | Distinguishing congenital long QT syndrome from QT prolongation caused by drugs or a different underlying disease process is essential for selecting the proper treatment. Herein, we present a case of a patient referred for left cardiac sympathetic denervation as a last resort treatment option for her 19-year standing d... |
15,082 | Alterations in adhesion junction precede gap junction remodelling during the development of heart failure in cardiomyopathic hamsters. | The intercalated disc (ID) contains two complexes, the adhesion junction (AJ) and the gap junction (GJ). We studied ID remodelling and its potential role in arrhythmogenesis and investigated the effects of olmesartan on ID remodelling during development of heart failure (HF) in UM-X7.1 cardiomyopathic hamsters.</Abstra... |
15,083 | Left stellate ganglion blockade for the management of drug-resistant electrical storm. |   Electrical storm (ES) is a syndrome characterized by rapidly recurrent ventricular fibrillation or tachycardia. The most common precipitants include ongoing or recent myocardial ischemia, exacerbating congestive heart failure, arrhythmogenic medications, and electrolyte disturbances.</AbstractText>  We ... |
15,084 | Coronary angiography and intervention during hypothermia can be performed safely without cardiac arrhythmia or vasospasm. | Mild therapeutic hypothermia is a neuroprotective procedure after cardiac arrest. Therefore, it is increasingly used. Likewise, there is a growing demand for coronary angiography and percutaneous coronary interventions under hypothermia. Case studies suggested that hypothermia may be associated with coronary vasospasm,... |
15,085 | Impact of renal failure on in-hospital outcomes after coronary artery bypass surgery. | Chronic kidney disease (CKD) is a predictor of increased mortality in patients undergoing coronary artery bypass surgery (CABG).</AbstractText>To evaluate the characteristics and predictors of increased mortality in the CKD population submitted to CABG. To compare in-hospital outcomes between patients with and without ... |
15,086 | [Risk stratification in Brugada syndrome]. | Individuals with type 1 Brugada ECG pattern may suffer from malignant ventricular arrhythmias (Brugada syndrome). Patients with Brugada syndrome and documented cardiac arrest should receive an implantable cardioverter-defibrillator. In the remaining subjects, the best management is controversial. Many data suggest that... |
15,087 | Perishock pause: an independent predictor of survival from out-of-hospital shockable cardiac arrest. | Perishock pauses are pauses in chest compressions before and after defibrillatory shock. We examined the relationship between perishock pauses and survival to hospital discharge.</AbstractText>We included out-of-hospital cardiac arrest patients in the Resuscitation Outcomes Consortium Epistry-Cardiac Arrest who suffere... |
15,088 | Single-center experience with implantable cardioverter-defibrillators in adults with complex congenital heart disease. | Adults with congenital heart disease are at risk of lethal ventricular arrhythmias and are candidates for implantable cardiac defibrillator (ICD) therapy, yet implant risks, long-term outcomes, and rates of appropriate and inappropriate ICD therapies are not well characterized. We reviewed clinical, implantation, and f... |
15,089 | Tissue doppler imaging and plasma BNP levels to assess the prognosis in patients with hypertrophic cardiomyopathy. | In addition to sudden death, heart failure and stroke due to atrial fibrillation are important in patients with hypertrophic cardiomyopathy (HCM). The aim of the present study was to determine whether Doppler tissue imaging findings and plasma B-type natriuretic peptide (BNP) levels, which are widely used for risk stra... |
15,090 | Electrocardiographic findings in patients with primary dysmenorrhea. | Primary dysmenorrhea (PD), which is characterized by painful menstrual cycles, is one of the common clinical problems in young adult women. The aim of this study was to investigate the risk of cardiac arrhythmias in PD patients by using the electrocardiographic (ECG) parameters.</AbstractText>Forty patients diagnosed w... |
15,091 | RETRACTED: Ventricular Ectopic Beats: An Overview of Management Considerations. | Ventricular ectopic beats are commonly seen in daily clinical practice. Majority of them being asymptomatic, some can cause symptoms. In a normal heart, their occurrence is of no clinical significance. However, in the presence of an underlying heart disease, they signify a susceptibility toward more sinister arrhythmia... |
15,092 | Importance of evaluating conduction block in radiofrequency ablation for atrial fibrillation. | Atrial fibrillation (AF) is the most frequently diagnosed cardiac arrhythmia. Anti-arrhythmic drugs may be used to suppress ectopic foci and interrupt reentry circuits, but are often insufficient to treat recurrent AF and have a number of adverse effects. Alternative therapies, such as catheter and surgical ablation, h... |
15,093 | Twelve hours of sustained ventricular fibrillation supported by a continuous-flow left ventricular assist device. | Left ventricular assist device (LVAD) therapy improves survival and quality of life by mechanically unloading the left ventricle and maintaining hemodynamics in patients with end-stage heart failure. LVADs can also be lifesaving by maintaining hemodynamics during ventricular arrhythmia. Continuous-flow LVADs have becom... |
15,094 | Acute heart failure with dyspnoea: initial treatment. Furosemide and trinitrine, despite the lack of a proven survival benefit. | For patients with acute heart failure and dyspnoea due to pulmonary congestion, the risk of death in the short term is high. To determine how best to manage these patients, we reviewed the relevant literature using the standard Prescrire methodology. There are few reliable clinical trial data. None of the available dru... |
15,095 | Appropriate therapy but not inappropriate shocks predict survival in implantable cardioverter defibrillator patients. | Inappropriate implantable cardioverter defibrillator (ICD) shocks have been linked to a worse clinical outcome due to direct myocardial injury.</AbstractText>The occurrence of ventricular tachyarrhythmia indicating progression of the underlying heart disease, but not the ICD shock itself, has prognostic impact in clini... |
15,096 | [Acute pulmonary embolism following cardiac arrest in a 31 year-old female with long QT syndrome]. | A case of a young female with acute pulmonary embolism following cardiac arrest due to ventricular fibrillation as a result of long QT syndrome is presented. A differential diagnosis has been discussed. |
15,097 | Microvolt T-wave alternans for the risk stratification of dangerous ventricular arrhythmias in patients with previously implanted automatic cardioverter-defibrillator. | Sudden cardiac death (SCD) is the main cause of death in patients with reduced left ventricular ejection fraction (LVEF). Implantation of an automatic cardioverter-defibrillator (ICD) significantly reduces mortality of these patients. T-wave alternans (TWA) analysis is a relatively new method of SCD risk stratification... |
15,098 | Prolonged P wave dispersion in pre-diabetic patients. | It is known that overt diabetes as well as chronic hyperglycaemia can lead to atrial fibrillation. A P wave dispersion (PWD) represents heterogeneity in atrial refractoriness.</AbstractText>To investigate PWDs in patients with pre-diabetes.</AbstractText>Based on the results of examinations, 84 pre-diabetic patients (t... |
15,099 | Intermediate and long-term followup of percutaneous device closure of fossa ovalis atrial septal defect by the Amplatzer septal occluder in a cohort of 529 patients. | The aim of present study is to analyze the intermediate and long-term follow up results of percutaneous closure of fossa ovalis atrial septal defect (ASD) with Amplatzer septal occluder (ASO) in a large cohort of patients including children and adults.</AbstractText>Between May 1998 and July 2008, 529 patients (age gro... |
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