Unnamed: 0 int64 0 2.34M | titles stringlengths 5 21.5M | abst stringlengths 1 21.5M |
|---|---|---|
2,327,800 | Microsurgical techniques for achieving gross total resection of ependymomas of the fourth ventricle. | Ependymomas arising from the ventricular surface present a major challenge to achieving a complete operative extirpation when located in the fourth ventricle given the presence of significant adherence to the floor of the same. Overzealous dissection and removal of a tumor from this zone may precipitate potentially cat... |
2,327,801 | Evolution of cerebellomedullary fissure opening: its effects on posterior fossa surgeries from the fourth ventricle to the brainstem. | Surgical approaches to the fourth ventricle and its surrounding brainstem regions have changed significantly in the previous 30 years, after the establishment of cerebellomedullary fissure (CMF) opening. With the development of CMF opening techniques, CMF opening surgeries have become widely used for the treatment... |
2,327,802 | An Overview of Nicotinic Cholinergic System Signaling in Neurogenesis. | The production of new neurons continues in the adult mammalian brain because of the sustained proliferation and differentiation of neural stem cells (NSCs) in neurogenic regions. The subventricular zone (SVZ), lining the lateral ventricle, and the subgranular zone (SGZ), which is in the dentate gyrus (DG) of the hippoc... |
2,327,803 | Prx2 (Peroxiredoxin 2) as a Cause of Hydrocephalus After Intraventricular Hemorrhage. | Background and Purpose- Our recent study demonstrated that release of Prx2 (peroxiredoxin 2) from red blood cells (RBCs) is involved in the inflammatory response and brain injury after intracerebral hemorrhage. The current study investigated the role of extracellular Prx2 in hydrocephalus development after experimental... |
2,327,804 | Optimal strategy for measuring intraventricular temperature using acceleration motion compensation diffusion-weighted imaging. | DWI thermometry is affected by CSF pulsation. To achieve more accurate determination of intraventricular temperature, we compared conventional DWI (c-DWI), acceleration motion compensation DWI (aMC-DWI), and motion compensation DWI (MC-DWI) when using two different b values (commonly used b value [1000 s/mm<sup>2<... |
2,327,805 | A methodological review of fetal neurosonographic studies: New directions in assessment of neurodevelopmental risk for mental health problems. | Most mental disorders are now considered to have neurodevelopmental origins, with a growing body of research pointing to neural alterations that predate birth. However, lack of established methods for reliable investigation of fetal brain development has limited research into early neural vulnerability. Using a systema... |
2,327,806 | Evolution of care pathways for babies with hypoplastic left heart syndrome: integrating mechanistic and clinical process investigation, standardization, and collaborative study. | Since initial descriptions of staged palliation for hypoplastic left heart syndrome (HLHS) in the 1980's, much has been learned about the pathophysiology of the single ventricle circulation. New therapies that leverage systems biology and clinical derivatives have been developed. While in-hospital mortality and morbidi... |
2,327,807 | Quantitative approach to numbers and sizes: Generation of primary neurospheres from the dorsal lateral ganglionic eminence of late embryonic mice. | <b>Background:</b> The neurosphere assay is a powerful <i>in vitro</i> tool to investigate neural stem cells in the dorsal lateral ventricle (dLGE). In the dLGE, metrics of sizes and numbers of neurospheres generated using this assay has not been completely characterized. The objective of this protocol is to provide a ... |
2,327,808 | The bitter taste receptor TAS2R14 regulates resveratrol transport across the human blood-cerebrospinal fluid barrier. | The regulation of transport mechanisms at brain barriers must be thoroughly understood, so that novel strategies for improving drug delivery to the brain can be designed. The blood-cerebrospinal fluid barrier (BCSFB) established by the choroid plexus (CP) epithelial cells has been poorly studied in this regard despite ... |
2,327,809 | Cardiac MR segmentation based on sequence propagation by deep learning. | Accurate segmentation of myocardial in cardiac MRI (magnetic resonance image) is key to effective rapid diagnosis and quantitative pathology analysis. However, a low-quality CMR (cardiac magnetic resonance) image with a large amount of noise makes it extremely difficult to accurately and quickly manually segment the my... |
2,327,810 | Neuroimaging Spectrum at Pre-, Early, and Late Symptomatic Stages of SCA17 Mice. | Spinocerebellar ataxia (SCA) is a hereditary neurodegenerative disease. We have generated SCA17 transgenic mice bearing human TBP with 109 CAG repeats under the Purkinje cell-specific L7/pcp2 promoter. These mice recapitulate the patients' phenotypes and are suitable for the study of the SCA17 pathomechanism. Magnetic ... |
2,327,811 | Neonatal Stroke and TLR1/2 Ligand Recruit Myeloid Cells through the Choroid Plexus in a CX3CR1-CCR2- and Context-Specific Manner. | Neonatal stroke is as frequent as stroke in the elderly, but many pathophysiological injury aspects are distinct in neonates, including immune signaling. While myeloid cells can traffic into the brain via multiple routes, the choroid plexus (CP) has been identified as a uniquely educated gate for immune cell traffic du... |
2,327,812 | [Anatomical study of rat trigeminal motor nucleus-lateral pterygoid muscle projection pathway]. | <b>Objective:</b> To determine the opening and closing action of the external muscle, the projection pathway of the axon terminal of trigeminal motor nucleus (Vmo) neuron to the lateral pterygoid muscle was revealed. <b>Methods:</b> In this study, 10 SD rats of 8 weeks old were included. The left lateral pterygoid musc... |
2,327,813 | Progressive subcortical volume loss in treatment-resistant schizophrenia patients after commencing clozapine treatment. | The association of antipsychotic medication with abnormal brain morphometry in schizophrenia remains uncertain. This study investigated subcortical morphometric changes 6 months after switching treatment to clozapine in patients with treatment-resistant schizophrenia compared with healthy volunteers, and the relationsh... |
2,327,814 | Microcephalic osteodysplastic primordial dwarfism type II: Additional nine patients with implications on phenotype and genotype correlation. | PCNT encodes a large coiled- protein localizing to pericentriolar material and is associated with microcephalic osteodysplastic primordial dwarfism type II syndrome (MOPD II). We report our experience of nine new patients from seven unrelated consanguineous Egyptian families with the distinctive clinical features of MO... |
2,327,815 | Corrigendum: Numerical Simulation of the Influence of Geometric Configurations on Pressure Difference in the Intraventricular Tunnel. | [This corrects the article DOI: 10.3389/fphys.2020.00133.]. |
2,327,816 | Tropical Endomyocardial Fibrosis. | Tropical endomyocardial fibrosis is a common cause of restrictive cardiomyopathy worldwide, but is relatively rare in developed countries. We present a case of tropical endomyocardial fibrosis with right ventricular involvement initially mistaken as Ebstein's anomaly. We highlight the need for timely and accurate diagn... |
2,327,817 | Dosimetric Comparison of Three Radiotherapy Techniques in Irradiation of Left-Sided Breast Cancer Patients after Radical Mastectomy. | The VMAT plans showed superior to PTV dose conformity index (CI), homogeneity index (HI), protection of the ipsilateral lung, monitor units (MUs), and maximum dose (Dmax</sub>) to the contralateral breast compared with TSP and 9FIMRT plans. The TSP provided better protection for Dmean</sub> of the heart and left ventri... |
2,327,818 | Prospective study to assess the survival outcomes of planned irradiation of ipsilateral subventricular and periventricular zones in glioblastoma. | <AbstractText Label="PURPOSE/OBJECTIVES" NlmCategory="OBJECTIVE">Retrospective evidence suggests that the irradiation of stem cells in the periventricular zone (PVZ), specifically the subventricular zone (SVZ), to higher doses may be associated with improved outcomes.</AbstractText><AbstractText Label="MATERIALS/METHOD... |
2,327,819 | Paeoniflorin Ameliorates Chronic Hypoxia/SU5416-Induced Pulmonary Arterial Hypertension by Inhibiting Endothelial-to-Mesenchymal Transition. | Endothelial cells dysfunction is one of the hallmark pathogenic features of pulmonary arterial hypertension (PAH). Paeoniflorin (PF) is a monoterpene glycoside with endothelial protection, vasodilation, antifibrotic, anti-inflammatory and antioxidative properties. However, the effects of PF on PAH remain unknown.</Abst... |
2,327,820 | Yolk sac tumor of the fourth ventricle in a 3-year-old boy: imaging features. | Yolk sac tumor (YST) is a rare malignant germ cell tumor and typically occurs in gonads. It is extremely rare in the brain, especially in the fourth ventricle.</AbstractText>This study reported the case of a 3-year-old boy with intermittent vomiting for 11 days and then intermittent twitch for 5 h.</AbstractT... |
2,327,821 | Multifaceted actions of Zeb2 in postnatal neurogenesis from the ventricular-subventricular zone to the olfactory bulb. | The transcription factor Zeb2 controls fate specification and subsequent differentiation and maturation of multiple cell types in various embryonic tissues. It binds many protein partners, including activated Smad proteins and the NuRD co-repressor complex. How Zeb2 subdomains support cell differentiation in various co... |
2,327,822 | Pravastatin alleviates intracellular calcium dysregulation induced by Interleukin-6 via the mitochondrial ROS pathway in adult ventricular myocytes. | Acute inflammation often contributes to the increased arrhythmogenesis in the cardiomyocytes. We investigated the protective effects of pravastatin on calcium disorders induced by acute administration of pro-inflammatory cytokines in isolated ventricular myocytes and its underlying mechanisms. Wild-type mice were intra... |
2,327,823 | A first case of meningitis/encephalitis associated with SARS-Coronavirus-2. | Novel coronavirus (SARS-Coronavirus-2:SARS-CoV-2) which emerged in Wuhan, China, has spread to multiple countries rapidly. We report the first case of meningitis associated with SARS-CoV-2 who was brought in by ambulance due to a convulsion accompanied by unconsciousness. He had never been to any foreign countries. He ... |
2,327,824 | Bitter taste receptors profiling in the human blood-cerebrospinal fluid-barrier. | The choroid plexus (CP) epithelial cells establish an important blood-brain interface, the blood-cerebrospinal fluid barrier (BCSFB), which constitutes a complementary gateway to the blood-brain-barrier for the entrance of several molecules into the central nervous system (CNS). However, the mechanisms that operate at ... |
2,327,825 | The role of dopamine D<sub>2</sub>-like receptors in a "depotentiation-like effect" of deep brain stimulation in kindled rats. | The mechanisms involved in the anti-seizure effects of low-frequency stimulation (LFS) have not been completely determined. However, G<sub>i</sub>-protein-coupled receptors, including D<sub>2</sub>-like receptors, may have a role in mediating these effects. In the present study, the role of D<sub>2</sub>-like receptors... |
2,327,826 | Establishment of Immortalized Laryngeal Epithelial Cells Transfected with Bmi1. | Primary laryngeal epithelial cells are essential to exploring the mechanisms of laryngeal and voice disorders; however, they are difficult to study and apply because of their limited life span. The purpose of this study was to develop a stable and reliable <i>in vitro</i> model for the comprehensive study of the pathog... |
2,327,827 | Pediatric septal dysembryoplastic neuroepithelial tumor (sDNT): case-based update. | The purpose of this study was to review a case of a septal dysembryoplastic neuroepithelial tumor (sDNT) and compare it to cases reported in the current literature.</AbstractText>We review a case of sDNT and compare with 7 other previously noted cases in the literature.</AbstractText>The mainstay treatment is gross tot... |
2,327,828 | Endoscopic third ventriculostomy in patients with myelomeningocele after shunt failure. | Myelomeningocele (MMC) is the most frequent form of spina bifida. Moreover, 90% of patients with MMC have hydrocephalus and require shunt placement. However, shunt failure management in such patients typically involves several shunt revisions, increasing the risk for morbidity and mortality. In this study, we report ou... |
2,327,829 | Morphofunctional status of cardio-vascular system of rats with arterial hypertension. | The aim: Was to clarify the general patterns of structural changes in the left ventricular myocardial capillaries in rats with spontaneous arterial hypertension.</AbstractText>Materials and methods: Experiments were conducted on 50 ISIAH (inherited stress-induced arterial hypertension) line rats with arterial hypertens... |
2,327,830 | Intracranial Fetus In Fetu-a Pediatric Rarity. | Intracranial fetus in fetu is an extremely rare entity in which a discrete vertebrate fetiform mass is found inside a diamniotic, monochorionic twin. It is a benign mass and can manifest with symptoms owing to mass effect. To establish the diagnosis, a vertebra must be present within the mass.</AbstractText>A 5-year-ol... |
2,327,831 | Thalamic Deep Brain Stimulation for tremor: The critical role of intraoperative testing. | Optimal placement of Deep Brain Stimulation (DBS) lead is critical to ensure an adequate therapeutic benefit and minimize stimulation-induced side effects.</AbstractText>We reviewed data from 2004 to 2018 of all cases of essential tremor treated with thalamic DBS at the University of Cincinnati. All procedures were per... |
2,327,832 | Retention of Gadolinium in Brain Parenchyma: Pathways for Speciation, Access, and Distribution. A Critical Review. | The unexpected appearance of T<sub>1</sub> hyperintensities, mostly in the dentate nucleus and the globus pallidus, during nonenhanced MRI was reported in 2014. This effect is associated with prior repeated administrations of gadolinium (Gd)-based contrast agents (GBCAs) in patients with a functional blood-brain barrie... |
2,327,833 | Transcriptional regulation of adult neural stem/progenitor cells: tales from the subventricular zone. | In rodents, well characterized neurogenic niches of the adult brain, such as the subventricular zone of the lateral ventricles and the subgranular zone of the hippocampus, support the maintenance of neural/stem progenitor cells (NSPCs) and the production of new neurons throughout the lifespan. The adult neurogenic proc... |
2,327,834 | Cerebrospinal fluid dynamics in idiopathic normal pressure hydrocephalus on four-dimensional flow imaging. | To evaluate complex CSF movements and shear stress in patients with idiopathic normal pressure hydrocephalus (iNPH) on four-dimensional (4D) flow MRI.</AbstractText>Three-dimensional velocities and volumes of the reciprocating CSF movements through 12 ROIs from the foramen of Monro to the upper cervical spine were meas... |
2,327,835 | Suprasellar central nervous system ganglioneuroblastoma: a case in a 9-year-old child and review of the literature. | Intracranial ganglioneuroblastomas are incredibly rare neuroectodermal tumors with only 8 described cases total, 5 of those having imaging findings METHODS: Here we present a 9-year-old female patient with 4 months progressive headaches, personality changes, and vomiting. We also present a review of the current li... |
2,327,836 | A validation study of manual atrophy measures in patients with Multiple Sclerosis. | Manual measures such as corpus callosum index, normalized corpus callosum area, and width of the third ventricle are potential biomarkers for brain atrophy. In this work, we investigate their suitability to assess the neurodegenerative component of multiple sclerosis (MS) by comparing them to volumetric measures and ex... |
2,327,837 | Improved myocardial perfusion PET imaging using artificial neural networks.<Pagination><StartPage>145010</StartPage><MedlinePgn>145010</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1088/1361-6560/ab8687</ELocationID><Abstract><AbstractText>Myocardial perfusion (MP) PET imaging plays a key role in r... | Myocardial perfusion (MP) PET imaging plays a key role in risk assessment and stratification of patients with coronary artery disease. In this work, we proposed a patch-based artificial neural network (ANN) fusion approach that integrates information from the ML and the post-smoothed ML reconstruction to improve MP PET... |
2,327,838 | Elevated p38MAPK activity promotes neural stem cell aging. | Age-progressive neural stem cell (NSC) dysfunction leads to impaired neurogenesis, cognitive decline and the onset of age-related neurodegenerative pathologies. p38MAPK signalling pathway limits stem cell activity during aging in several tissues. Its role in NSCs remains controversial. In this work, we show that p38MAP... |
2,327,839 | The impact of increased pulmonary arterial pressure on outcomes after transcatheter aortic valve replacement.<Pagination><StartPage>E723</StartPage><EndPage>E734</EndPage><MedlinePgn>E723-E734</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/ccd.28862</ELocationID><Abstract><AbstractText Label="O... | The aim of our study was to study and analyze the electrophysiological indicators of rhythm disturbances in heart failure in elderly people who participated in the elimination of the consequences of the Chernobyl accident in the distant period. In order to assess the functional features, 50 elderly patients (65-74 year... |
2,327,840 | Cardiomyocyte slowly activating delayed rectifier potassium channel: regulation by exercise and β-adrenergic signaling. | Exercise training is known to prolong the ventricular cardiomyocyte action potential duration (APD), increasing Ca<sup>2+</sup> influx and contractility. The prolonged APD is caused, in part, by a decreased responsiveness to β-adrenergic agonists. The study's aims were to elucidate the mechanisms by which exercis... |
2,327,841 | The mammillothalamic tracts: Age-related conspicuity and normative morphometry on brain magnetic resonance imaging. | The mammillothalamic tract (MTT, bundle of Vicq d'Azyr) is a white-matter projection from each mammillary body to the anterior nucleus of the thalamus (ANT). Deep brain stimulation of the MTTs or ANTs is a treatment option for medically refractory focal epilepsy. Since the ANTs may be atrophied in epilepsy, targeting o... |
2,327,842 | Diffusion MRI changes in the anterior subventricular zone following chemoradiation in glioblastoma with posterior ventricular involvement. | There is growing evidence that the subventricular zone (SVZ) plays a key role in glioblastoma (GBM) tumorigenesis. However, little is known regarding how the SVZ, which is a harbor for adult neural stem cells, may be influenced by chemoradiation. The current diffusion-weighted imaging (DWI) study explored ipsilateral a... |
2,327,843 | Silver-impregnated, antibiotic-impregnated or non-impregnated ventriculoperitoneal shunts to prevent shunt infection: the BASICS three-arm RCT. | Hydrocephalus (commonly known as ‘water on the brain’) is a condition that can affect all age groups, from babies to the elderly. In hydrocephalus, there is an accumulation of the normal brain fluid in the fluid cavities (ventricles) of the brain. Untreated, hydrocephalus can be life-threatening. The most... |
2,327,844 | Angiomodulin (IGFBP7) is a cerebral specific angiocrine factor, but is probably not a blood-brain barrier inducer. | Several secreted factors have been identified as drivers of cerebral vasculature development and inducers of blood-brain barrier (BBB) differentiation. Vascular endothelial growth factor A (VEGF-A) is central for driving cerebral angiogenesis and Wnt family factors (Wnt7a, Wnt7b and norrin) are central for induction an... |
2,327,845 | [Experimental study on effect and mechanism of Danzhi Jiangtang Capsules on diabetic myocardial injury]. | Diabetic cardiomyopathy( DCM) is one of the major cardiovascular complications of diabetes mellitus. Based on the clinical efficacy of Danzhi Jiangtang Capsules( DJC) in the prevention and treatment of diabetes and its cardiovascular complications,both in vivo and in vitro methods were adopted to investigate its effect... |
2,327,846 | Primary intracranial intraventricular leiomyoma: a literature review. | Leiomyomas, benign tumors of well-differentiated smooth muscle and vascular collagenous tissue, usually occur in the uterus but can develop wherever smooth muscle is present. Primary intracranial leiomyomas are rare tumors. We present the case of a 40-year-old woman with a primary intraventricular leiomyoma. She consul... |
2,327,847 | MT1-MMP deficiency leads to defective ependymal cell maturation, impaired ciliogenesis, and hydrocephalus. | Hydrocephalus is characterized by abnormal accumulation of cerebrospinal fluid (CSF) in the ventricular cavity. The circulation of CSF in brain ventricles is controlled by the coordinated beating of motile cilia at the surface of ependymal cells (ECs). Here, we show that MT1-MMP is highly expressed in olfactory bulb, r... |
2,327,848 | Loss of leptin receptor-expressing cells in the hindbrain decreases forebrain leptin sensitivity. | Previous studies indicate that inhibition of food intake by leptin is mediated by an integrated response to activation of hypothalamic and hindbrain receptors. This study tested whether loss of hindbrain leptin receptor signaling changed sensitivity to forebrain leptin. Injections of leptin-conjugated saporin (Lep-Sap)... |
2,327,849 | Tumor Location and Treatment Modality are Associated with Overall Survival in Adult Medulloblastoma. | Introduction Medulloblastoma (MB) is an aggressive brain tumor most commonly found in children. Although prognostic factors are well studied in children, factors affecting survival in adults with medulloblastoma are unclear. Methods We queried the 1973-2015 United States Surveillance, Epidemiology, and End Results (SEE... |
2,327,850 | Spontaneous hemispheric ventricular collapse and subarachnoid haemorrhages in a dog with congenital hydrocephalus internus. | Overdrainage and collapse of the hemispheres is a potential severe complication after surgical treatment of internal hydrocephalus using ventriculoperitoneal shunts. Here we describe a case of a spontaneous hemispheric ventricular collapse in an untreated dog with congenital hydrocephalus internus.</AbstractText>A twel... |
2,327,851 | Medicinal Plants and Phytochemicals for the Treatment of Pulmonary Hypertension.<Pagination><StartPage>145</StartPage><MedlinePgn>145</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">145</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.3389/fphar.2020.00145</ELocationID><Abstract><AbstractText Labe... | Here, we describe an in vitro culture assay to study coronary angiogenesis. Coronary vessels feed the heart muscle and are of clinical importance. Defects in these vessels represent severe health risks such as in atherosclerosis, which can lead to myocardial infarctions and heart failures in patients. Consequently, cor... |
2,327,852 | Structural changes in the brain on cranial magnetic resonance imaging in severely malnourished children before and after treatment. | The aim of this study was to examine the structural changes in brain on magnetic resonance imaging (MRI) in severely malnourished children before and after treatment.</AbstractText>This was a prospective study conducted at a Severe Malnutrition Treatment Unit (SMTU) at a tertiary care center. The study was carried out ... |
2,327,853 | ETV in infancy and childhood below 2 years of age for treatment of hydrocephalus. | Age and etiology play a crucial role in success of endoscopic third ventriculostomy (ETV) as a treatment of obstructive hydrocephalus. Outcome is worse in infants, and controversies still exist whether ETV is superior to shunt placement. We retrospectively analyzed 70 patients below 2 years from 4 different center... |
2,327,854 | Retrospective analysis of the clinical and radiological features of 94 consecutive DIPGs patients to investigate the factors determining the development of hydrocephalus and its impact on clinical status and survival. | There is no consensus in the literature about the impact of hydrocephalus on clinical course and overall survival of diffuse intrinsic pontine gliomas (DIPG) patients as well as about its specific treatment. Authors reviewed a series of DIPG patients to investigate factors related to the onset of hydrocephalus, its tre... |
2,327,855 | A deep learning-based approach for automatic segmentation and quantification of the left ventricle from cardiac cine MR images. | Cardiac MRI has been widely used for noninvasive assessment of cardiac anatomy and function as well as heart diagnosis. The estimation of physiological heart parameters for heart diagnosis essentially require accurate segmentation of the Left ventricle (LV) from cardiac MRI. Therefore, we propose a novel deep learning ... |
2,327,856 | Pediatric rosette-forming glioneuronal tumor of the septum pellucidum. | Rosette-forming glioneuronal tumor (RGNT) is a rare tumor entity which has been reported mainly occurring in the fourth ventricle. It has been described as a benign lesion with limited extension into surrounding structures, including the cerebellar vermis, midbrain, and cerebral aqueduct. More recently, few cases invol... |
2,327,857 | Entrainment of mammalian motile cilia in the brain with hydrodynamic forces. | Motile cilia are widespread across the animal and plant kingdoms, displaying complex collective dynamics central to their physiology. Their coordination mechanism is not generally understood, with previous work mainly focusing on algae and protists. We study here the entrainment of cilia beat in multiciliated cells fro... |
2,327,858 | Intracranial myxoid mesenchymal tumor with EWSR1-CREB1 gene fusion: a case report and literature review. | Intracranial myxoid mesenchymal tumors harboring EWSR1 fusions with CREB transcriptional factor gene families were recently described in several case reports and a few case series and this tumor closely resembles the myxoid variant of angiomatoid fibrous histiocytoma. We herein present an intracranial mesenchymal myxoi... |
2,327,859 | Changes of third ventricle diameter (TVD) mirror changes of the entire ventricular system at acute shunt failure and after shunt revision in pediatric hydrocephalus. | In hydrocephalic children, regular investigations of the ventricles are important for initial diagnosis and after initial treatment. Our recent study showed that changes of the third ventricle diameter (TVD) reliably reflect changes of the entire ventricular system at diagnosis and following initial therapy. This study... |
2,327,860 | Correction to: CT compared to MRI for functional evaluation of the right ventricle: a systematic review and meta-analysis. | The original version of this article, published on 27 May 2019, unfortunately contained mistakes. |
2,327,861 | Association between scripture memorization and brain atrophy using magnetic resonance imaging. | We investigated the association between scripture memorization and brain tissue using magnetic resonance imaging techniques. Participants comprised 63 healthy adults between the ages of 35 and 80 years old with no neurological or psychological disorders. Of these, 19 had completely memorized the Quran, 28 had partially... |
2,327,862 | Hindbrain metabolic deficiency regulates ventromedial hypothalamic nucleus glycogen metabolism and glucose‑regulatory signaling. | The catecholamine norepinephrine (NE) links hindbrain metabolic‑sensory neurons with downstream gluco‑regulatory loci, including the ventromedial hypothalamic nucleus (VMN). Exogenous NE up‑regulates VMN expression of glutamate decarboxylase (GAD), biomarker for the gluco‑inhibitory transmit... |
2,327,863 | Semaglutide lowers body weight in rodents via distributed neural pathways. | Semaglutide, a glucagon-like peptide 1 (GLP-1) analog, induces weight loss, lowers glucose levels, and reduces cardiovascular risk in patients with diabetes. Mechanistic preclinical studies suggest weight loss is mediated through GLP-1 receptors (GLP-1Rs) in the brain. The findings presented here show that semaglutide ... |
2,327,864 | Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species. | Cerebrospinal fluid contacting neurons (CSF-cNs) represent a specific class of neurons located in close vicinity of brain ventricles and central canal. In contrast with knowledge gained from other vertebrate species, we found that vast majority of CSF-cNs in the spinal cord of C57Bl/6N mice is located in ectopic distal... |
2,327,865 | Regional volume changes of the brain in migraine chronification. | The pathophysiology of migraine is complex. Neuroimaging studies reveal functional and structural changes in the brains of migraine patients. We sought to explore regional volume differences in intracranial structures in patients with episodic and chronic migraine. Sixteen episodic migraine patients, 16 chronic migrain... |
2,327,866 | [A case of intramyocardial dissecting haematoma]. | 患者为60岁男性。因胸痛入院，心电图提示急性ST段抬高型下壁心肌梗死，冠状动脉造影显示... |
2,327,867 | White Matter High Signals Interfere with Noncontrast Computed Tomography in the Early Identification of Cerebral Infarction. | We developed an image patch classification-based method to detect early ischemic stroke. The accuracy of this method was >75%. We aimed to analyze patients' image data to identify interference factors that would affect its accuracy.</AbstractText>We conducted a retrospective analysis of 162 patients who were hospita... |
2,327,868 | A retrospective regional study of aqueduct stenosis and fourth ventricle outflow obstruction in the paediatric complex neurofibromatosis type 1 population; Aetiology, clinical presentation and management. | Aqueduct stenosis (AS) and fourth ventricle outflow obstruction are rare associations of neurofibromatosis type 1 (NF1), resulting in ventriculomegaly and hydrocephalus requiring surgical treatment. This study aims to identify the prevalence of AS and its patterns of clinical presentation, aetiology and treatment in th... |
2,327,869 | ECE2 regulates neurogenesis and neuronal migration during human cortical development. | During embryonic development, excitatory projection neurons migrate in the cerebral cortex giving rise to organised layers. Periventricular heterotopia (PH) is a group of aetiologically heterogeneous disorders in which a subpopulation of newborn projection neurons fails to initiate their radial migration to the cortex,... |
2,327,870 | Cardiac fiber tracking on super high-resolution CT images: a comparative study. | <b>Purpose:</b> High-resolution cardiac imaging and fiber analysis methods are required to understand cardiac anatomy. Although refraction-contrast x-ray CT (RCT) has high soft tissue contrast, it cannot be commonly used because it requires a synchrotron system. Microfocus x-ray CT ( <mml:math xmlns:mml="http://www.w3.... |
2,327,871 | Near-infrared light driven tissue-penetrating cardiac optogenetics via upconversion nanoparticles in vivo. | This study determines whether near-infrared (NIR) light can drive tissue-penetrating cardiac optical control with upconversion luminescent materials. Adeno-associated virus (AAV) encoding channelrhodopsin-2 (ChR2) was injected intravenously to rats to achieve ChR2 expression in the heart. The upconversion nanoparticles... |
2,327,872 | Optimization of combined measures of airway physiology and cardiovascular hemodynamics in mice. | Pulmonary hypertension may arise as a complication of chronic lung disease typically associated with tissue hypoxia, as well as infectious agents or injury eliciting a type 2 immune response. The onset of pulmonary hypertension in this setting (classified as Group 3) often complicates treatment and worsens prognosis of... |
2,327,873 | Cerebral localization of higher functions: Memory-related anatomic structures. | The nature of memory and the search for its localization have been a subject of interest since Antiquity. After millennia of theoretical concepts, shifting from the heart to the brain, then from the ventricles to solid parts, the core memory-related structures finally began to be identified through modern scientificall... |
2,327,874 | Analysis of mast cells and myocardial fibrosis in autopsied patients with hypertensive heart disease. | To analyze the percentage of collagen fibers and mast cell density in the left ventricular myocardium of autopsied patients with and without hypertensive heart disease.</AbstractText>Thirty fragments of left ventricular myocardium were obtained from individuals autopsied at the Clinical Hospital of the Federal Universi... |
2,327,875 | [Streptozocin-induced Alzheimer's disease as an independent risk factor for the development of hyperglycemia in Wistar rats]. | Обоснование. В последние годы широко обсуждается теC... |
2,327,876 | [Xiao's "<i>xingnaofusu</i>" needling for regaining consciousness and the influence on width of the third ventricle in patients with persistent vegetative state]. | To observe the influence of Xiao's "xingnaofusu</i>" needling (the technique for resuscitation) on regaining consciousness in the patients with persistent vegetative state (PVS).</AbstractText>A total of 50 patients of PVS were randomized into an observation group and a control group, 25 cases in each. The patients in ... |
2,327,877 | A rare case of intralesional haemorrhage of a benign aqueductal cyst after CSF diversion treatment. A case report and review of literature. | Benign cysts within the pure aqueductal region are a rare entity. Their critical location within the ventricular system presents a risk of potentially catastrophic outcomes. We present a case of a 68-year-old female who was transferred to our unit with an acute obstructive triventricular hydrocephalus caused by a benig... |
2,327,878 | Remote Supratentorial Subdural Hematoma Following Craniectomy and Evacuation of Hypertensive Cerebellar Hematoma. | Remote acute subdural hematoma following a decompressive craniotomy or craniectomy is a rare phenomenon. Only few cases of postoperative contralateral acute subdural hematomas have been reported in the literature review till date. This case report details a case of a 32-year-old hypertensive male who presented with sev... |
2,327,879 | Extracellular matrix components isolated from diabetic mice alter cardiac fibroblast function through the AGE/RAGE signaling cascade. | Individuals suffering from diabetes have an increased risk of developing cardiovascular complications such as heart failure. Heart failure can be a result of the stiffening of the left ventricle, which occurs when cardiac fibroblasts become "active" and begin to remodel the extracellular matrix (ECM). Fibroblast "activ... |
2,327,880 | Colocalized neurotransmitters in the hindbrain cooperate in adaptation to chronic hypernatremia. | Chronic hypernatremia activates the central osmoregulatory mechanisms and inhibits the function of the hypothalamic-pituitary-adrenal (HPA) axis. Noradrenaline (NE) release into the periventricular anteroventral third ventricle region (AV3V), the supraoptic (SON) and hypothalamic paraventricular nuclei (PVN) from effer... |
2,327,881 | Cannabinol in the spotlight: Toxicometabolomic study and behavioral analysis of zebrafish embryos exposed to the unknown cannabinoid. | Cannabinol (CBN) is a degradation product of the cannabis metabolite Δ9-tetrahydrocannabinol. The CBN concentration in cannabis leaves ranges between 0.1 and 1.6% (w/w of dry weight); it increases as the plant ages and its formation is affected by the storage conditions. As CBN has not been extensively studied so... |
2,327,882 | Aqueductal Compression by Dilated Virchow-Robin Spaces in the Mesencephalic-Pontine Region Presenting with Symptoms Mimicking Normal Pressure Hydrocephalus: A Case Report and Review of Literature. | Dilatation of Virchow-Robin spaces (dVRS) have been described in the development of hydrocephalic syndromes. We report an unusual case of a type III dVRS presenting as a mimic of normal pressure hydrocephalus (NPH), due to distortion at the level of the cerebral aqueduct.</AbstractText>A 59-year-old woman presented wit... |
2,327,883 | MAST1 variant causes mega-corpus-callosum syndrome with cortical malformations but without cerebellar hypoplasia. | We report the case of a Caucasian Spanish origin female who showed severe psychomotor developmental delay, hypotonia, strabismus, epilepsy, short stature, and poor verbal language development. Brain magnetic resonance imaging scans showed thickened corpus callosum, cortical malformations, and dilated and abnormal confi... |
2,327,884 | Polyplex transfection from intracerebroventricular delivery is not significantly affected by traumatic brain injury. | Traumatic brain injury (TBI) is largely non-preventable and often kills or permanently disables its victims. Because current treatments for TBI merely ameliorate secondary effects of the initial injury like swelling and hemorrhaging, strategies for the induction of neuronal regeneration are desperately needed. Recent d... |
2,327,885 | Spontaneous Third Ventriculostomy in Krabbe Disease.<Pagination><StartPage>99</StartPage><EndPage>105</EndPage><MedlinePgn>99-105</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.pediatrneurol.2019.11.014</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0887-8994(19)30932-4</ELocationID><Ab... | Aortic injury is a rarely encountered complication of spinal surgery. The authors report a case of a 32-year-old woman with a T3 tumor who experienced an intraoperative aortic arch injury during T3 spondylectomy. The patient was successfully treated with no postoperative neurological deficits. |
2,327,886 | Long-term postnatal outcome of fetuses with prenatally suspected septo-optic dysplasia. | Septo-optic dysplasia (SOD) is a clinical syndrome characterized by varying combinations of optic nerve hypoplasia, pituitary gland hypoplasia and abnormal cavum septi pellucidi. It is suspected on prenatal imaging when there is non-visualization or hypoplasia of the septal leaflets. Long-term postnatal outcomes of fet... |
2,327,887 | H3K27M mutant diffuse midline glioma: a case report. | Diffuse midline glioma with H3K27M mutation is a new tumor type of WHO central nervous system tumor classification. It often occurs in the midline structure and usually has a poor prognosis.</AbstractText>A 38-year-old male patient presented with 2 years history of right limb with facial numbness, tumors in the left th... |
2,327,888 | Differences in Expression of Mitochondrial Complexes Due to Genetic Variants May Alter Sensitivity to Radiation-Induced Cardiac Dysfunction. | Radiation therapy is received by over half of all cancer patients. However, radiation doses may be constricted due to normal tissue side effects. In thoracic cancers, including breast and lung cancers, cardiac radiation is a major concern in treatment planning. There are currently no biomarkers of radiation-induced car... |
2,327,889 | Targeted alpha therapy in a systemic mouse model of prostate cancer - a feasibility study. | <sup>225</sup>Ac-PSMA-617 targeted-therapy has demonstrated efficacy in 75-85% of patients; however, responses are not durable. We aimed to establish translatable mouse models of disseminated prostate cancer (PCa) to evaluate effectiveness of <sup>225</sup>Ac-PSMA-617 at various disease stages. <b>Methods</b>: C4-2, C4... |
2,327,890 | Involvement of Wnt7a in the role of M2c microglia in neural stem cell oligodendrogenesis. | The participation of microglia in CNS development and homeostasis indicate that these cells are pivotal for the regeneration that occurs after demyelination. The clearance of myelin debris and the inflammatory-dependent activation of local oligodendrocyte progenitor cells in a demyelinated lesion is dependent on the ac... |
2,327,891 | Distribution of aromatase in the brain of the African cichlid fish Astatotilapia burtoni: Aromatase expression, but not estrogen receptors, varies with female reproductive-state. | Estrogen synthesis and signaling in the brains of vertebrates has pleotropic effects ranging from neurogenesis to modulation of behaviors. The majority of studies on brain-derived estrogens focus on males, but estrogenic signaling in females likely plays important roles in regulation of reproductive cycling and social ... |
2,327,892 | Fast Localization and Sectioning of Mouse Locus Coeruleus. | The locus nucleus (LC) is a multifunctional nucleus which is also the source of norepinephrine in the brain. To date, there is no simple and easy method to locate the small LC in brain sectioning. Here we report a fast, accurate, and easy-to-follow protocol for the localization of mice LC in frozen sectioning. After fi... |
2,327,893 | The clinical, radiological, and immunohistochemical characteristics and outcomes of primary intracranial gliosarcoma: a retrospective single-centre study. | Primary intracranial gliosarcoma is a rare malignant brain tumour, and the most effective treatment for gliosarcoma remains unclear. This study aimed to identify risk factors for progression-free survival (PFS) and overall survival (OS) in these cases. This retrospective single-centre study evaluated 103 patients (medi... |
2,327,894 | Real-Time In Vivo Imaging of Mouse Left Ventricle Reveals Fluctuating Movements of the Intercalated Discs. | Myocardial contraction is initiated by action potential propagation through the conduction system of the heart. It has been thought that connexin 43 in the gap junctions (GJ) within the intercalated disc (ID) provides direct electric connectivity between cardiomyocytes (electronic conduction). However, recent studies c... |
2,327,895 | Subventricular zone-derived extracellular vesicles promote functional recovery in rat model of spinal cord injury by inhibition of NLRP3 inflammasome complex formation. | Spinal cord injury (SCI) is the destruction of spinal cord motor and sensory resulted from an attack on the spinal cord, which can cause significant physiological damage. The inflammasome is a multiprotein oligomer resulting in inflammation; the NLRP3 inflammasome composed of NLRP3, apoptosis-associated speck-like prot... |
2,327,896 | Management of multiloculated hydrocephalus in children with emphasis on role of CT ventriculography. | The authors performed a retrospective review of children diagnosed with multiloculated hydrocephalus (MLH) in our institute. The goal was to analyze the different diagnostic and therapeutic modalities used with special emphasis on CT ventriculography (CTV).</AbstractText>Male and female patients below the age of 18
... |
2,327,897 | Right ventricle in adulthood: CT and MR assessment. | Anatomical complexities coupled with a protracted subclinical disease course, particularly in the early stages, makes the right ventricle (RV) the less studied entity when compared with the left. RV failure is an important predictor of survival in patients with cardiovascular disease. Technological advances have made i... |
2,327,898 | Lrig1 expression prospectively identifies stem cells in the ventricular-subventricular zone that are neurogenic throughout adult life. | Leucine-rich repeats and immunoglobulin-like domains 1 (Lrig1) regulates stem cell quiescence. As a marker, it identifies stem cells in multiple organs of the mouse. We had detected Lrig1 expression in cultured Id1high</sup> neural stem cells obtained from the lateral walls lining the lateral ventricles of the adult mo... |
2,327,899 | Neocortical tissue recovery in severe congenital obstructive hydrocephalus after intraventricular administration of bone marrow-derived mesenchymal stem cells. | In obstructive congenital hydrocephalus, cerebrospinal fluid accumulation is associated with high intracranial pressure and the presence of periventricular edema, ischemia/hypoxia, damage of the white matter, and glial reactions in the neocortex. The viability and short time effects of a therapy based on bone marrow-de... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.