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25,200 | Multicohort Metabolomics Analysis Discloses 9-Decenoylcarnitine to Be Associated With Incident Atrial Fibrillation. | Background The molecular mechanisms involved in atrial fibrillation are not well known. We used plasma metabolomics to investigate if we could identify novel biomarkers and pathophysiological pathways of incident atrial fibrillation. Methods and Results We identified 200 endogenous metabolites in plasma/serum by nontar... |
25,201 | Impact of QRS morphology on response to conduction system pacing after atrioventricular junction ablation. | His-Purkinje conduction system pacing (HPCSP) utilizing His (HBP) or left bundle branch pacing (LBBP) in patients with atrial fibrillation (AF) and wide QRS duration has not been well studied. We assessed the benefit of left bundle branch block (LBBB) correction during HPCSP in AF patients undergoing atrioventricular j... |
25,202 | A review of indications and comorbidities in which warfarin may be the preferred oral anticoagulant. | Direct oral anticoagulants (DOACs) are increasingly prescribed instead of warfarin for chronic anticoagulation for ease of dosing, fewer interactions, and less stringent monitoring. However, it is important to consider indications and comorbidities for which warfarin is still the preferred anticoagulant. This review ai... |
25,203 | Association of type 2 diabetes mellitus with the development of new-onset atrial fibrillation in patients with non-ischemic dilated cardiomyopathy: impact of SGLT2 inhibitors. | The aim of this study was to investigate the association of type 2 diabetes mellitus (T2DM) with the development of new-onset atrial fibrillation (AF) for non-ischemic dilated cardiomyopathy (DCM) patients. We also tested the hypothesis that sodium glucose cotransporter type 2 (SGLT2) inhibitors reduce the risk of deve... |
25,204 | The predictive value of epicardial adipose tissue volume assessed by cardiac magnetic resonance for atrial fibrillation in patients with hypertrophic obstructive cardiomyopathy. | Atrial fibrillation (AF) is the most common arrhythmia and potentially increase the risk of embolic stroke and aggravate progressive heart failure in patients with hypertrophic cardiomyopathy (HCM). Recent studies demonstrated that epicardial adipose tissue (EAT) was closely associated with AF in general population. Ho... |
25,205 | Prognosis and clinical characteristics of patients with early ventricular fibrillation in the 6-week guideline-offered time period: is it safe to wait 6 weeks with the assessment? (results from the VMAJOR-MI Registry). | The most common, potentially fatal complication following an acute myocardial infarction (AMI) is early ventricular fibrillation (EVF). According to the guidelines, the assessment of implanting an implantable cardioverter defibrillator (ICD) is sufficient 6 weeks after the event, in patients with reduced left ventricul... |
25,206 | Paroxysmal atrial fibrillation in a dog that was presented for neck wounds. | A 12-year-old spayed female German shorthaired pointer dog sustained extensive bite wounds around the neck. At presentation, atrial fibrillation was identified with a rapid ventricular response rate of 300 beats per minute (bpm). The ventricular response rate rapidly decreased to 130 bpm following administration of hyd... |
25,207 | Unusual Overlapping Cardiac Sarcoidosis and Long-QT Type 3 Induced Ventricular Fibrillation. | A 54-year-old woman had been resuscitated after ventricular fibrillation and her electrocardiogram showed a QT prolongation (QTc=510 ms), and genetic screening revealed a missense variant, R1644C, in the SCN5A gene. She was therefore diagnosed with congenital long-QT syndrome (LQTS) type 3. However, the patient had lef... |
25,208 | Incremental diagnostic role of left atrial strain analysis in thrombotic risk assessment of nonvalvular atrial fibrillation patients planned for electrical cardioversion. | During the COVID-19 pandemic, transesophageal echocardiography (TEE) for left atrial appendage thrombosis (LAAT) detection should be limited to situations of absolute necessity. We sought to identify the main conventional and functional echocardiographic parameters associated with LAAT on TEE in non-valvular atrial fib... |
25,209 | The year in cardiovascular medicine 2020: arrhythmias. | of the progress in arrhythmias in 2020. RACE4 and ALL-IN indicated that integrated nurse-led care improves outcomes in AF patients.3,4 The same was reported for early rhythm control therapy15 and cryoablation as initial AF treatment.25,26 Subcutaneous ICD was non-inferior to classical transvenous ICD therapy in PRAETOR... |
25,210 | Right atrial volume is a major determinant of tricuspid annulus area in functional tricuspid regurgitation: a three-dimensional echocardiographic study. | The aim of this study is to explore the relationships of tricuspid annulus area (TAA) with right atrial maximal volume (RAVmax) and right ventricular end-diastolic volume (RVEDV) in healthy subjects and patients with functional tricuspid regurgitation (FTR) of different aetiologies and severities.</AbstractText>We enro... |
25,211 | The fatal consequence of inappropriate therapy in a single VF zone primary prevention defibrillator. | We report a case of inappropriate implantable cardioverter defibrillator (ICD) therapy due to single ventricular fibrillation (VF) zone programming leading to patient death. A remote transmission was received from a patient with a cardiac resynchronization therapy-defibrillator showing sinus tachycardia in the VF detec... |
25,212 | Is mitral annuloplasty an effective treatment for severe atrial functional mitral regurgitation? | Unlike secondary mitral regurgitation (MR) in the setting of left ventricular disease, results of surgical treatment of severe atrial functional MR has remained largely unspoken. The aim of this study is to analyze short to midterm results of isolated ring annuloplasty in patients with severe atrial functional MR, in c... |
25,213 | The transient outward potassium current plays a key role in spiral wave breakup in ventricular tissue. | Spiral wave reentry as a mechanism of lethal ventricular arrhythmias has been widely demonstrated in animal experiments and recordings from human hearts. It has been shown that in structurally normal hearts spiral waves are unstable, breaking up into multiple wavelets via dynamical instabilities. However, many of the s... |
25,214 | Amiodarone induced pulmonary toxicity. | Amiodarone is one of the more frequently used drugs in the treatment of supraventricular and ventricular arrhythmias. Many adverse effects, more or less serious, are associated with its administration. Amiodaron-induced pulmonary toxicity (AIPT) is quite rare but represents one of the most severe adverse effects with h... |
25,215 | Electocardiographic features in Ebstein's disease. | <b>Introduction:</b>Ebstein's disease (ED) is a rare and heterogeneous congenital heart disease affecting the tricuspid valve and the right ventricle. Few studies have analyzed the electrocardiographic features of this disease. <b>Aim:</b> To describe the electrocardiographic features observed in Ebstein's disease <b>M... |
25,216 | Left atrial appendage closure with Watchman device: Insights from the first-ever Tunisian experience and six-year follow-up. | Stroke is a major complication of nonvalvular atrial fibrillation (AF). Despite its proven efficacy in stroke prevention, oral anticoagulation (OAC) is associated to a significant increase in bleeding complications. New techniques such as percutaneous left atrial appendage (LAA) closure were developed.</AbstractText>To... |
25,217 | Short-period temporal repolarization dispersion in subjects with atrial fibrillation and decompensated heart failure. | <AbstractText Label="BACKGROUND/OBJECTIVES">The association between chronic heart failure (CHF) and permanent atrial fibrillation is very frequent. The repolarization duration was already found predictive for atrial fibrillation. Aim of this study was to evaluate the influence of atrial fibrillation on short period rep... |
25,218 | Can permanent His bundle pacing be safely started by operators new to this technique? Data from a multicenter registry. | Right ventricular pacing (RVP) induces ventricular asynchrony in patients with normal QRS and increases the risk of heart failure and atrial fibrillation in long term. His bundle pacing (HBP) is a physiological alternative to RVP, and could overcome its drawbacks. Recent studies assessed the feasibility and safety of H... |
25,219 | Prognostic value of left atrial volume index in acute coronary syndrome: A systematic review and meta-analysis. | In the absence of mitral valve disease, increased left atrial volume (LAV) is a marker of diastolic dysfunction and long-standing elevated left ventricle (LV) pressure. The aim of this study was to assess the role of increased baseline LAV in predicting clinical outcome of patients presenting with acute coronary syndro... |
25,220 | Ventricular fibrillation due to coronary spasm after pepper spray. | Pepper spray is used as a crowd control agent and for self-defense. It has been thought to be safe; however, 27 persons have died in police custody after exposure to pepper spray. We report on a 21-year-old man, with no underlying heart disease and a normal ECG and echocardiogram in the past, who was pepper sprayed and... |
25,221 | Brugada syndrome and syncope: a practical approach for diagnosis and treatment. | Syncope in patients with Brugada electrocardiogram pattern may represent a conundrum in the decision algorithm because incidental benign forms, especially neurally mediated syncope, are very frequent in this syndrome similarly to the general population. Arrhythmic syncope in Brugada syndrome typically results from a se... |
25,222 | Life-threatening arrhythmias with autosomal recessive TECRL variants. | Sudden death and aborted sudden death have been observed in patients with biallelic variants in TECRL. However, phenotypes have only begun to be described and no data are available on medical therapy after long-term follow-up.</AbstractText>An international, multi-centre retrospective review was conducted. We report ne... |
25,223 | Influence of Chronic Obstructive Pulmonary Disease on Atrial Mechanics by Speckle Tracking Echocardiography in Patients With Atrial Fibrillation. | The present study aimed to examine differences in left- and right atrial characteristics between atrial fibrillation (AF) patients with and without chronic obstructive pulmonary disease (COPD). For this, 420 patients (mean age 68 ± 10 years, 73% female) with first diagnosis of AF and baseline echocardiography were... |
25,224 | Systolic Blood Pressure and Risk for Ventricular Arrhythmia in Patients With an Implantable Cardioverter Defibrillator. | Low systolic blood pressure (SBP) was previously suggested to be a marker for heart failure and mortality in patients with low left ventricular ejection fraction. We aimed to explore the association of SBP on risk of ventricular tachyarrhythmias (VTA) and atrial arrhythmias as well as appropriate and inappropriate Impl... |
25,225 | Unique technique to relieve left ventricular assist device electromagnetic interference with an implantable cardioverter defibrillator. | We introduced a simple technique to eliminate electromagnetic interference between a left ventricular assist device (LVAD) and an implantable cardioverter defibrillator (ICD). A 43-year-old male with heart failure and a reduced ejection fraction who had an ICD presented with decompensated heart failure and received an ... |
25,226 | Two siblings with early repolarization syndrome: clinical and genetic characterization by whole-exome sequencing. | The early repolarization syndrome (ERS) can cause ventricular fibrillation (VF) and sudden death in young, otherwise healthy individuals. There are limited data suggesting that ERS might be heritable. The aim of this study was to characterize the clinical phenotype and to identify a causal variant in an affected family... |
25,227 | Ventricular arrhythmia burden during the coronavirus disease 2019 (COVID-19) pandemic. | Our objective was to determine the ventricular arrhythmia burden in implantable cardioverter-defibrillator (ICD) patients during COVID-19.</AbstractText>In this multicentre, observational, cohort study over a 100-day period during the COVID-19 pandemic in the USA, we assessed ventricular arrhythmias in ICD patients fro... |
25,228 | No impact of mineralocorticoid receptor antagonists on long-term recurrences of ventricular tachyarrhythmias. | The study sought to assess the prognostic impact of treatment with mineralocorticoid receptor antagonists (MRA) on recurrences of ventricular tachyarrhythmias in implantable cardioverter-defibrillator (ICD) recipients with systolic heart failure (HF).</AbstractText>Data regarding the outcome of patients with ventricula... |
25,229 | Prediction of low-voltage areas using modified APPLE score. | The presence of low-voltage areas (LVAs) in patients with atrial fibrillation (AF) reflects left atrial (LA) electroanatomical substrate, which is essential for individualized AF management. However, echocardiographic anteroposterior LA diameter included into previous LVAs prediction scores does not mirror LA size accu... |
25,230 | Pulsed field ablation: a promise that came true. | Pulsed field ablation is a nonthermal ablative modality that uses short living, strong electrical field created around catheter to create microscopic pores in cell membranes (electroporation). When adequately dosed/configured it shows a preference for myocardial tissue necrosis. Thus, it holds a promise to become a 'pe... |
25,231 | Do Elderly Patients With Diastolic Dysfunction Require Higher Doses of Norepinephrine During General Anesthesia for Noncardiac Surgeries? A Prospective Observational Study. | Diastolic dysfunction is a risk factor for postoperative major cardiovascular events. During anesthesia, patients with diastolic dysfunction might experience impaired hemodynamic function and worsening of diastolic function, which in turn, might be associated with a higher incidence of postoperative complications.We ai... |
25,232 | Prognostic value of left ventricular mechanical dyssynchrony in hypertrophic cardiomyopathy patients with low risk of sudden cardiac death. | This study aims to explore the prognostic value of left ventricular mechanical dyssynchrony (LVMD) in hypertrophic cardiomyopathy (HCM) patients with low risk of sudden cardiac death (SCD).</AbstractText>This retrospective study was performed in 50 patients with HCM who underwent Tc-99m sestamibi GSPECT-MPI. All patien... |
25,233 | Long-term outcome of myocardial scarring and deformation with cardiovascular magnetic resonance in out of hospital cardiac arrest survivors. | Cardiovascular magnetic resonance (CMR) is increasingly recognized as a diagnostic and prognostic tool in out of hospital cardiac arrest (OHCA) survivors. After assessing CMR findings early after ventricular fibrillation (VF) OHCA, we sought to explore the long-term outcome of myocardial scarring and deformation.</Abst... |
25,234 | Characteristics and long-term outcomes of aortico-left ventricular tunnel. | Aortico-left ventricular tunnel (ALVT) is an extremely rare, abnormal paravalvular communication between the aorta and the left ventricle. Few studies have identified the characteristics and long-term prognosis associated with ALVT.</AbstractText>The data of 31 patients with ALVT from July 2002 to December 2019 were re... |
25,235 | Prognosis of paradoxical low-flow low-gradient aortic stenosis after transcatheter aortic valve replacement. | In paradoxical low-flow low-gradient severe aortic stenosis (PLFLG AS) patients, stroke volume index (SVI) is reduced despite preserved left ventricular ejection fraction (LVEF). Although reduced SVI is already known as a poor prognostic predictor, the outcomes of PLFLG AS patients after transcatheter aortic valve repl... |
25,236 | Arrhythmias and Pregnancy: Management of Preexisting and New-Onset Maternal Arrhythmias. | Arrhythmias are the most common cardiovascular complication of pregnancy in women with and without structural heart disease. Appropriate maternal diagnosis and management is of utmost importance to optimize maternal and fetal outcomes. A multidisciplinary care approach with cardiology, maternal fetal medicine, anesthes... |
25,237 | Brugada syndrome genetics is associated with phenotype severity. | Brugada syndrome (BrS) is associated with an increased risk of sudden cardiac death due to ventricular tachycardia/fibrillation (VT/VF) in young, otherwise healthy individuals. Despite SCN5A being the most commonly known mutated gene to date, the genotype-phenotype relationship is poorly understood and remains uncertai... |
25,238 | Impact of contact force sensing technology on outcome of catheter ablation of idiopathic pre-mature ventricular contractions originating from the outflow tracts. | Catheter ablation of frequent idiopathic pre-mature ventricular contractions (PVC) is increasingly performed. While potential benefits of contact force (CF)-sensing technology for atrial fibrillation ablation have been assessed in several studies, the impact of CF-sensing on ventricular arrhythmia ablation remains unkn... |
25,239 | Infanticide vs. inherited cardiac arrhythmias. | In 2003, an Australian woman was convicted by a jury of smothering and killing her four children over a 10-year period. Each child died suddenly and unexpectedly during a sleep period, at ages ranging from 19 days to 18 months. In 2019 we were asked to investigate if a genetic cause could explain the chil... |
25,240 | Risk of arrhythmias after myocardial infarction in patients with left ventricular systolic dysfunction according to mode of revascularization: a Cardiac Arrhythmias and RIsk Stratification after Myocardial infArction (CARISMA) substudy. | The Cardiac Arrhythmias and RIsk Stratification after Myocardial infArction (CARISMA) study was an observational trial including 312 patients with acute myocardial infarction (MI) and left ventricular ejection fraction (LVEF) <40%. Primary percutaneous intervention (pPCI) was introduced 2 years after start of... |
25,241 | Early repolarization in the inferolateral leads predicts the presence of vasospastic angina: a novel predictor in patients with resting angina. | An association between early repolarization and ventricular fibrillation has recently been reported in patients with vasospastic angina (VSA). However, no studies have clarified whether the presence of early repolarization can predict VSA.</AbstractText>Participants comprised 286 patients (136 males) with clinically su... |
25,242 | Spontaneous coronary artery dissection and Takotsubo syndrome: comparison of baseline clinical and angiographic characteristics and in-hospital outcomes. | Spontaneous coronary artery dissection (SCAD) and Takotsubo syndrome (TTS) constitute two relatively common nonatherosclerotic causes of acute coronary syndrome particularly frequent in women.</AbstractText>This study sought to compare the baseline clinical and angiographic characteristics and in-hospital outcomes of p... |
25,243 | Cardiac arrhythmias amongst hospitalised Coronavirus 2019 (COVID-19) patients: Prevalence, characterisation, and clinical algorithm to classify arrhythmic risk. | A significant proportion of COVID-19 patients may have cardiac involvement including arrhythmias. Although arrhythmia characterisation and possible predictors were previously reported, there are conflicting data regarding the exact prevalence of arrhythmias. Clinically applicable algorithms to classify COVID patients' ... |
25,244 | Spontaneous Coronary Artery Dissection: Does Being Unemployed Matter? Insights from the GSCAD Registry. | Spontaneous coronary artery dissection (SCAD) has emerged as an important cause of acute coronary syndrome (ACS) and sudden cardiac death. Physical or emotional stressors are the most commonly reported triggers for SCAD. Unemployment has been identified as a source of emotional stress and is linked to poor mental and p... |
25,245 | QTc Interval Prolongation and Life-Threatening Arrhythmias During Hospitalization in Patients With Coronavirus Disease 2019 (COVID-19): Results From a Multicenter Prospective Registry. | Prolonged QTc intervals and life-threatening arrhythmias (LTA) are potential drug-induced complications previously reported with antimalarials, antivirals, and antibiotics. Our objective was to evaluate the prevalence and predictors of QTc interval prolongation and incidences of LTA during hospitalization for coronavir... |
25,246 | Association of Hydroxychloroquine Use With Decreased Incident Atrial Fibrillation in Systemic Lupus Erythematosus. | To study the relationship between hydroxychloroquine (HCQ) use and new-onset atrial fibrillation in patients with systemic lupus erythematosus (SLE).</AbstractText>A retrospective cohort of adult patients with SLE was constructed from December 1, 2014 to May 30, 2017. Patients were categorized as either HCQ users or no... |
25,247 | Electrocardiographic findings at presentation and clinical outcome in patients with SARS-CoV-2 infection. | The main severe complications of SARS-CoV-2 infection are pneumonia and respiratory distress syndrome. Recent studies, however, reported that cardiac injury, as assessed by troponin levels, is associated with a worse outcome in these patients. No study hitherto assessed whether the simple standard electrocardiogram (EC... |
25,248 | The use of direct oral anticoagulants in patients with ventricular assist devices: Is there hope for Factor Xa inhibition? | The use of continuous-flow ventricular assist devices (cf-VAD) necessitates systemic anticoagulation, routinely with vitamin K antagonists (VKA). Newer direct oral anticoagulants (DOACs) have significant advantages over VKA in providing a predictable level of systemic anticoagulation without frequent monitoring or stri... |
25,249 | Non-invasive detection of exercise-induced cardiac conduction abnormalities in sudden cardiac death survivors in the inherited cardiac conditions. | Rate adaptation of the action potential ensures spatial heterogeneities in conduction across the myocardium are minimized at different heart rates providing a protective mechanism against ventricular fibrillation (VF) and sudden cardiac death (SCD), which can be quantified by the ventricular conduction stability (V-CoS... |
25,250 | Cardiovascular Toxicity and Mortality Associated With Adoptive Cell Therapy and Tumor-infiltrating Lymphocytes for Advanced Stage Melanoma. | Adoptive cellular therapy (ACT) with tumor-infiltrating lymphocytes (TILs) has emerged as an effective treatment option for unresectable stage III/IV metastatic melanoma. Acute toxicities, particularly cardiovascular (CV), can have a significant effect on the completion of therapy. We abstracted information on 43 patie... |
25,251 | Idiopathic ventricular fibrillation: the ongoing quest for diagnostic refinement. | Prior to the recognition of distinct clinical entities, such as Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia, and long QT syndrome, all sudden cardiac arrest (SCA) survivors with ventricular fibrillation (VF) and apparently structurally normal hearts were labelled as idiopathic ventricular fi... |
25,252 | Prospective follow-up in various subtypes of cardiomyopathies: insights from the ESC EORP Cardiomyopathy Registry. | The European Society of Cardiology (ESC) European Observational Research Programme (EORP) Cardiomyopathy Registry is a prospective multinational registry of consecutive patients with cardiomyopathies. The objective of this report is to describe the short-term outcomes of adult patients (≥18 years old).</A... |
25,253 | Calmodulinopathies: throwing back the veil on the newest life-threatening genetic arrhythmia syndrome. | This review provides a basic understanding of the calmodulin gene and its role in calcium homeostasis. We outline the functional effects and clinical expression of CALM mutations and review disease expression and management.</AbstractText>Calmodulinopathies are rare life-threatening arrhythmia syndromes affecting young... |
25,254 | Frequency, predictors and prognostic impact of implantable cardioverter defibrillator shocks in a primary prevention population with heart failure and reduced ejection fraction. | The role of the implantable cardioverter defibrillator (ICD) in primary prevention real-world population is debated. We sought to evaluate the incidence, predictors and prognostic impact of ICD shocks in consecutive heart failure patients implanted for primary prevention at our tertiary institution.</AbstractText>We re... |
25,255 | Ventricular arrhythmias in Takotsubo Syndrome: incidence, predictors and clinical outcomes. | To investigate predictors of the occurrence of subacute ventricular arrhythmias (VAs), defined as any VAs presenting after 48 h from admission in patients with Takotsubo Syndrome (TTS), and to evaluate the related in-hospital mortality.</AbstractText>This is a retrospective single-center study enrolling patients... |
25,256 | The inflammation-resolution promoting molecule resolvin-D1 prevents atrial proarrhythmic remodelling in experimental right heart disease. | Inflammation plays a role in atrial fibrillation (AF), but classical anti-inflammatory molecules are ineffective. Recent evidence suggests that failure of inflammation-resolution causes persistent inflammatory signalling and that a novel drug-family called resolvins promotes inflammation-resolution. Right heart disease... |
25,257 | Echocardiographic predictors of cardiovascular morbidity and mortality in women from the general population. | Global longitudinal strain (GLS) is a strong predictor of adverse cardiovascular outcome in men. However, studies have indicated that GLS may not predict cardiovascular outcomes as effectively in women. The aim of this study was to identify echocardiographic predictors of cardiovascular morbidity and mortality in women... |
25,258 | Colchicine for the treatment of cardiovascular diseases: old drug, new targets. | : Well known in past centuries as a herbal remedy for osteoarticular pain and commonly used in the treatment of gout and familial Mediterranean fever, colchicine has an emerging role in the setting of cardiovascular diseases. Its unique properties not only target the key mechanisms of recurrent inflammation underlying ... |
25,259 | End-Tidal Carbon Dioxide Impacts Brain and Kidney Injury in Experimental Extracorporeal Cardiopulmonary Resuscitation (ECPR). | Extracorporeal membrane oxygenation-assisted cardiopulmonary resuscitation (ECPR) is proposed for cardiac resuscitation in selected cases. End-tidal carbon dioxide (ETCO2) is easily obtained during conventional cardiopulmonary resuscitation (CPR). We hypothesized that the level of ETCO2 during CPR would reflect the deg... |
25,260 | Novel Density Poincaré Plot Based Machine Learning Method to Detect Atrial Fibrillation From Premature Atrial/Ventricular Contractions. | Detection of Atrial fibrillation (AF) from premature atrial contraction (PAC) and premature ventricular contraction (PVC) is difficult as frequent occurrences of these ectopic beats can mimic the typical irregular patterns of AF. In this paper, we present a novel density Poincaré plot-based machine learning method... |
25,261 | The use of novel oral anticoagulants compared to vitamin K antagonists (warfarin) in patients with left ventricular thrombus after acute myocardial infarction. | Current guidelines recommend the use of vitamin K antagonist (VKA) for up to 3-6 months for treatment of left ventricular (LV) thrombus post-acute myocardial infarction (AMI). However, based on evidence supporting non-inferiority of novel oral anticoagulants (NOAC) compared to VKA for other indications such as d... |
25,262 | Clinical Presentation and Outcome of Patients With Spontaneous Coronary Artery Dissection Versus Atherosclerotic Coronary Plaque Dissection. | Atherosclerotic coronary plaque dissection (ACPD) is one cause of acute coronary syndrome (ACS) caused by underlying atherosclerosis. Spontaneous coronary artery dissection (SCAD) occurs outside the setting of atherosclerosis among young women and individuals with few or no conventional atherosclerotic risk factors, an... |
25,263 | Arrhythmic event prediction in patients with heart failure and reduced ejection fraction. | Implantable cardioverter defibrillator (ICD) is an effective treatment to reduce mortality in patients with symptomatic heart failure and left ventricular ejection fraction (LVEF) 35% or less. LVEF presents a low sensitivity for predicting arrhythmic events. Aim of this study was to identify predictors of sustained ven... |
25,264 | Recommendations for participation in leisure-time physical activity and competitive sports in patients with arrhythmias and potentially arrhythmogenic conditions: Part 1: Supraventricular arrhythmias. A position statement of the Section of Sports Cardiology and Exercise from the European Association of Preventive Cardi... | Symptoms attributable to arrhythmias are frequently encountered in clinical practice. Cardiologists and sport physicians are required to identify high-risk individuals harbouring such conditions and provide appropriate advice regarding participation in regular exercise programmes and competitive sport. The three aspect... |
25,265 | Pathogenesis of chronic heart failure: cardiovascular aging, risk factors, comorbidities, and disease modifiers. | Chronic heart failure (HF) is rare in the young and common in the elderly in the Western world. HF in the young is usually due to specific causes, predominantly or exclusively affecting the heart (adult congenital heart disease, different types of cardiomyopathies, myocarditis, or cardiotoxicity). In contrast, the mech... |
25,266 | Effects of Different Target Temperatures on Angiogenesis and Neurogenesis Following Resuscitation in a Porcine Model After Cardiac Arrest. | The optimal effective temperature of targeted temperature management (TTM) used to prevent cerebral injury following cardiopulmonary resuscitation (CPR) is undetermined. In this study, we compared the mortality, neurologic deficits, and cerebral protein levels of two target temperatures.</AbstractText>Fifty 4-month-old... |
25,267 | Positron Emission Tomography Imaging of Long-Term Expression of the 18 kDa Translocator Protein After Sudden Cardiac Arrest in Rats. | Knowledge about the neuroinflammatory state during months after sudden cardiac arrest is scarce. Neuroinflammation is mediated by cells that express the 18 kDa translocator protein (TSPO). We determined the time course of TSPO-expressing cells in a rat model of sudden cardiac arrest using longitudinal in vivo positron ... |
25,268 | Ventricular fibrillation mechanism and global fibrillatory organization are determined by gap junction coupling and fibrosis pattern. | Conflicting data exist supporting differing mechanisms for sustaining ventricular fibrillation (VF), ranging from disorganized multiple-wavelet activation to organized rotational activities (RAs). Abnormal gap junction (GJ) coupling and fibrosis are important in initiation and maintenance of VF. We investigated whether... |
25,269 | Wolff Parkinson White and recreational (meth)amphetamine use: a potentially lethal combination. | Cardiac arrest in Wolff-Parkinson-White (WPW) is a rare event, and although some patients appear to be at greater risk, there is no consensus on clear risk factors. We present a case of a 23-year-old male patient, with a known history of WPW pattern, who suffered an out of hospital ventricular fibrillation after the co... |
25,270 | Masters Athlete Screening Study (MASS): Insights Into the Psychological Impact of Cardiovascular Preparticipation Screening. | To determine the psychological impact of a cardiovascular disease (CVD) diagnosis identified during preparticipation screening (PPS) of masters athletes.</AbstractText>Cross-sectional study.</AbstractText>Masters athletes diagnosed with CVD through the Masters Athletes Screening Study.</AbstractText>Sixty-seven athlete... |
25,271 | Prognostic power of left atrial strain in patients with acute heart failure. | Left atrial (LA) dysfunction can be associated with left ventricular (LV) disorders; however, its clinical significance has not been well-studied in patients with acute heart failure (AHF). We evaluated prognostic power of peak atrial longitudinal strain (PALS) of the left atrium according to heart failure (HF) phenoty... |
25,272 | Inhibition of N-type calcium channels in cardiac sympathetic neurons attenuates ventricular arrhythmogenesis in heart failure. | Cardiac sympathetic overactivation is an important trigger of ventricular arrhythmias in patients with chronic heart failure (CHF). Our previous study demonstrated that N-type calcium (Cav2.2) currents in cardiac sympathetic post-ganglionic (CSP) neurons were increased in CHF. This study investigated the contribution o... |
25,273 | Role of atrial arrhythmia and ventricular response in atrial fibrillation induced atrial remodelling. | No studies have assessed the specific contributions of atrial fibrillation (AF)-related atrial vs. associated ventricular arrhythmia to remodelling. This study assessed the roles of atrial arrhythmia vs. high ventricular rate in AF-associated remodelling.</AbstractText>Four primary dog-groups (12/group) were subje... |
25,274 | Simple risk models to predict cardiovascular death in patients with stable coronary artery disease. | Risk estimation is important to motivate patients to adhere to treatment and to identify those in whom additional treatments may be warranted and expensive treatments might be most cost effective. Our aim was to develop a simple risk model based on readily available risk factors for patients with stable coronary artery... |
25,275 | Cardiovascular complications in patients with idiopathic inflammatory myopathies: does heart matter in idiopathic inflammatory myopathies? | This review presents a detailed study of original researches and previously published reviews concerning cardiovascular involvement in idiopathic inflammatory myopathies (IIM). We aimed to summarize the current knowledge on the cardiac involvement in IIM, evaluate its impact on mortality and indicate areas still awaiti... |
25,276 | Atrial Fibrillation Induced From Commotio Cordis. | A 20-year-old male collegiate basketball player was evaluated for sudden chest pain, shortness of breath, dizziness, and blurry vision, following an elbow to the anterior chest by another player. His symptoms improved over 10 minutes of observation, but rhythm strip performed onsite showed atrial fibrillation, and the ... |
25,277 | Risk factors for atrial fibrillation in hypertrophic cardiomyopathy. | Atrial fibrillation is the most common sustained arrhythmia in hypertrophic cardiomyopathy (HCM), occurring in approximately 25% of patients, which is four to six times more common than in similarly aged patients of the general population. Atrial fibrillation is poorly tolerated by HCM patients, largely due to their de... |
25,278 | COVID-19 management in heart transplanted recipients: registry of Almazov
National Medical Research Centre. | Aim This study presents the experience of managing patients with COVID-19
after cardiac transplantation (CT).Material and methods Infectious
complications (IC) following CT are a leading cause for morbidity and mortality.
A prolonged incubation period, atypical IC symptoms, and originally altered
results of l... |
25,279 | [The role of diastolic transthoracic stress echocardiography with incremental
workload in the evaluation of heart failure with preserved ejection fraction:
indications, methodology, interpretation. Expert consensus developed under the
auspices of the National Medical Research Center of Cardiology, Society of
Expert... | Diagnosis of heart failure with preserved ejection fraction (HFpEF) is
associated with certain difficulties since many patients with HFpEF have a
slight left ventricular diastolic dysfunction and normal filling pressure at
rest. Diagnosis of HFpEF is improved by using diastolic transthoracic
stress-echocardiography... |
25,280 | [Computed Tomography Coronary Angiography Possibilities in "High Risk" Plaque
Identification in Patients with non-ST-Elevation Acute Coronary Syndrome:
Comparison with Intravascular Ultrasound]. | Aim To evaluate structural characteristics of atherosclerotic plaques (ASP)
by coronary computed tomography arteriography (CCTA) and intravascular
ultrasound (IVUS).Material and methods This study included 37 patients with
acute coronary syndrome (ACS). 64-detector-row CCTA, coronarography, and
grayscale IVUS... |
25,281 | [Assessment of the Dynamics of Oxidative Stress Indicators and Early Markers of
Myocardial Damage and Dysfunction in Patients with Aggressive
Lymphoproliferative Diseases During of Anticancer Therapy]. | Aim To evaluate the dynamics of indexes of oxidative stress and markers of
myocardial injury and dysfunction in patients with aggressive type lymphomas
during the antitumor therapy.Material and methods This study included 75
patients with lymphoproliferative diseases of aggressive type. The main group
consist... |
25,282 | Gender Differences in Vascular Stiffness Indicators and Daily Blood Pressure
Profile in Patients with Arterial Hypertension and Depressive Disorders. | Aim To study gender-related characteristics of vascular wall stiffness
(VWS), central blood pressure (CBP), and BP diurnal profile in patients with
arterial hypertension (AH) and depression.Material and methods This
prospective, noninterventional study enrolled 161 patients, including 98
patients with AH and ... |
25,283 | ["Ictal" Bradyarrhythmias in Patients with Drug-Resistant Epilepsy: Results of
Long-Term Heart Rhythm Monitoring]. | Aim To determine the type and incidence of ictal bradyarrhythmias in
patients with drug-resistant types of epilepsy by long-term electrocardiogram
(ECG) monitoring.Material and methods Subcutaneous ECG monitors programed for
recording pauses >3 sec and episodes of bradycardia ≤45 bpm were implanted in
193 ... |
25,284 | [The new Epoch of Antithrombotic Therapy in the Long-Term Prevention of a
non-Cardioembolic Stroke]. | This article presents current opinions on the role of antithrombotic therapy in
secondary prevention of cardiovascular diseases (CVD) in patients after
noncardioembolic stroke or a transient ischemic attack on the background of
sinus rhythm. This review analytically analyses evidence-based data on
antithrombotic dr... |
25,285 | [Asymptomatic Hyperuricemia: Treatment Approaches According to the Risk of
Cardiovascular and Renal Events]. | Asymptomatic hyperuricemia (HU) is widespread in the population. Results of
multiple studies have demonstrated independent associations between increased
levels of uric acid and risk of arterial hypertension, cardiovascular diseases,
and chronic kidney disease. HU is considered as an independent predictor of
cardio... |
25,286 | [Echocardiography in the Assessment of Postsystolic Shortening of the Left
Ventricle Myocardium of the Heart]. | Echocardiography allows evaluating left ventricular (LV) myocardial
contractility; however, the visual assessment of contractility is subjective and
requires considerable experience. Modern technologies for assessment of LV
myocardial contractility, such as tissue Doppler and speckle-tracking
echocardiography, prov... |
25,287 | [Antibiotic prophylaxis for infective endocarditis: current approaches]. | This review addresses current views on prevention of infectious endocarditis
(IE). History of establishing the concept of antibacterial prophylaxis (ABP),
major approaches, and substantiation of changes in ABP in recent years are
described. Recent international and national guidelines are highlighted,
specifically,... |
25,288 | [Detection of peripheral artery disease in patients with ischemic heart disease.
A quick guide for medical practitioners]. | In this manual, the authors focused on the principal methods for diagnosis of
peripheral artery disease in cardiological patients, from the interview and
physical examination to functional tests and vascular visualization. Diagnostic
and prognostic value of each method, its potentialities for reducing the risk of
c... |
25,289 | The role of prognostic nutritional index in patients with non-ST segment
elevation acute coronary syndrome. | Objective The importance of nutritional status in non-ST segment elevated acute
coronary syndrome (NSTE-ACS) is not clear. In this study, the importance of
prognostic nutritional index (PNI) in terms of in-hospital mortality in patients
with NSTE-ACS and its relationship with the Global Record of Acute Coronary
Eve... |
25,290 | An early echocardiographic prediction for functional myocardial recovery after
ST elevation myocardial infarction. | Goals Discrimination of the time course of functional recovery in early period
following ST elevation myocardial infarction (STEMI) has prognostic importance.
This study aims to establish the ability of the combined systolic-diastolic
index (E / (Ea x Sa), for differentiating recoverable myocardium or persistent
no... |
25,291 | [Atherosclerotic Cardiovascular Diseases and Type 2 Diabetes Mellitus - new
Developments in the Treatment]. | Despite obvious success in the management of patients with type 2 diabetes
mellitus, incidence of myocardial infarction, stroke, critical ischemia, and
lower extremity amputation remains high. Results of clinical studies of new
hypoglycemic drugs have demonstrated their high efficacy in decreasing
mortality, incide... |
25,292 | [Infective Endocarditis with Unknown Etiology: Possibilities of Conquering and
Role of Microbiologistics]. | Current infectious endocarditis (IE) is characterized by changes in its
etiological and epidemiological profiles associated with increased incidence of
IE of undetermined etiology. This requires a search for ways to enhance the
effectivity of diagnosis. Microbiologistics along with high-tech methods becomes
decisiv... |
25,293 | [Classification of stages of severe aortic stenosis based on the prevalence of
extravalvular heart damage]. | This thematic review focuses on recently proposed classification of stages in
pronounced aortic stenosis based on the prevalence of extravalvular cardiac
damage and its modified variant designed for asymptomatic patients. The review
presents studies, which analyzed the predictive significance of the proposed
classi... |
25,294 | Approach to decongestion therapy in patients with acute decompensated heart
failure: the echocardiography guided strategy. | Goal The E / (Ea×Sa) index is an echocardiographic parameter to determine a
patient's left ventricular filling pressure. This study aims to determine the
safety and efficacy of the echocardiographic E / (Ea×Sa) index guided diuretic
therapy compared to urine output (conventional) guided diuretic
treatment.Material ... |
25,295 | The new classification method in ACEF score is more useful in patients with
acute coronary syndrome without ST segment elevation. | Goal In this study, it was investigated whether the age, creatinine, and
ejection fraction (ACEF) score [age (years) / ejection fraction (%) +1 (if
creatinine >2 mg / dL)] could predict in-hospital mortality in patients with
non-ST-elevation acute coronary syndrome (NSTE-ACS) and its relationship with
the Global... |
25,296 | [The no-Reflow Phenomenon During Primary Percutaneous Coronary Intervention in
Patients With ST-Segment Elevation Myocardial Infarction due to Massive Coronary
Thrombosis. Pathogenesis and Predictors of no-Reflow]. | Despite successful and timely revascularization of the infarct-related artery,
myocardial tissue remains underperfused in some patients. This condition is
known as the no-reflow phenomenon, which is associated with a worse prognosis.
The first part of the systematic review on no-reflow focuses on description of
the... |
25,297 | [The case of recurrent tako-tsubo syndrome on the background of coronary
atherosclerosis]. | Takotsubo syndrome (TS) is characterized with a reversible disorder of left
ventricular contractility. At present time, it is established that various
factors, both psycho-emotional and clinical, can trigger this disease. Notably,
according to current opinions, coronary atherosclerosis may accompany TS and not
be i... |
25,298 | Clinical Characteristics and Factors Associated with Poor Outcomes in
Hospitalized Patients with Novel Coronavirus Infection COVID-19. | Aim To evaluate the clinical picture and factors associated with
unfavorable outcomes in admitted patients with COVID-19.Material and methods
This study included all patients admitted to the COVID Center of the National
Research Center of Cardiology of the Russian Ministry of Health Care from May 1
through May... |
25,299 | Proactive anti-inflammatory therapy with colchicine in the treatment of advanced
stages of new coronavirus infection. The first results of the COLORIT study. | Actuality The course of the novel coronavirus disease (COVID-19) is
unpredictable. It manifests in some cases as increasing inflammation to even the
onset of a cytokine storm and irreversible progression of acute respiratory
syndrome, which is associated with the risk of death in patients. Thus,
proactive anti-infl... |
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