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28,300 | Use of the peripheral cutting balloon to treat hemodialysis-related stenoses. | To compare the effectiveness and safety of use of the peripheral cutting balloon (PCB) versus standard percutaneous transluminal angioplasty (PTA) for the treatment of hemodialysis-related stenoses.</AbstractText>This prospective, randomized multicenter clinical trial included 340 patients with stenotic or thrombosed h... |
28,301 | [Thromboembolic risk and prevention of deep venous thrombosis in open and laparoscopic surgery]. | Deep Vein Thrombosis (DVT) and pulmonary embolism are the dangerous and serious complications in patients undergoing surgery. It is known that prognosis is strictly linked to timely recognition of the pathogenetic-clinical phase of the thromboembolic disease and that prevention, therefore, plays the leading role in pat... |
28,302 | [Treatment options in deep vein thrombosis]. | In the event of a deep vein thrombosis, the major concern is to prevent the subsequent development of an embolism or a recurrence. The therapeutic time gap to the development of the full effect of the vitamin K antagonists is bridged in the initial acute treatment phase with low molecular weight heparin (LMWH) or fonda... |
28,303 | [Diagnosing deep vein thrombosis in the leg]. | As a consequence of changes in lifestyle, an ageing population sometimes overdoing things in terms of sports activities, long-haul travel and an increasing incidence of malignomas, deep vein thrombosis (DVT) is increasingly being seen in ambulatory patients. The incidence of DVT is some 0.1-0.3%, and increases with age... |
28,304 | Successful diagnosis of thromboembolism before surgery in a woman with clear cell adenocarcinoma of the endometrium. | Patients with ovarian cancer with clear cell histology often have venous thromboembolism (VTE) even before surgery. In view of the possible association between clear cell histology and VTE in endometrial cancer, we measured the plasma levels of thrombin-antithrombin III complex (TAT) and D-dimer (DD) in the preoperativ... |
28,305 | Usefulness of catheter-directed thrombolysis using alteplase in peripheral vascular occlusion. | This study evaluated the safety and efficacy of alteplase in catheter-directed treatment for peripheral arterial and venous thrombosis and considered the optimal dosing regimen. Forty-four patients (49 encounters) underwent transcatheter therapy using alteplase between January and November 1999. The most common indicat... |
28,306 | Budd-Chiari syndrome: current options in interventional radiology treatment exemplified by three selected cases. | Budd-Chiari syndrome (BCS) is rare clinical state characterized by stenosis or complete obstruction of hepatic veins. Currently, interventional radiology techniques are more frequently used as a single method of treatment or as a bridge to liver transplantation.</AbstractText>This study presents current interventional ... |
28,307 | Extensive arterial and venous thrombosis in a patient with ulcerative colitis--a case report. | Vascular thrombosis is a rare but well-recognized extraintestinal manifestation of ulcerative colitis. Thrombosis usually involves the peripheral veins and less commonly the cerebral veins and the arterial system.</AbstractText>A case of a 22-year-old woman is reported who presented with an exacerbation of ulcerative c... |
28,308 | [Prothrombotic state in early stages of chronic Chagas' disease. Its association with thrombotic risk factors]. | The aim of this study was to explore the presence of prothrombotic state in early stages of chronic Chagas' disease with serum markers of thrombosis and fibrinolysis, and to investigate it's association with thrombotic risk factors for venous thromboembolic disease.</AbstractText>Forty two patients with chronic Chagas'... |
28,309 | Massive macular hard exudates associated with branch retinal vein occlusion. | To report four cases of branch retinal vein occlusion (BRVO) with the complication of serous retinal detachment (SRD).</AbstractText>We retrospectively studied four eyes of four patients with macular edema and macular hard exudates associated with midperipheral BRVO. Visual acuity, ophthalmoscopy, fluorescein angiograp... |
28,310 | Preexisting morbidity as an independent risk factor for perioperative acute thromboembolism syndrome. | Preexisting morbidities are risk factors for perioperative arterial or venous thromboembolic events and subsequent death within 30 postoperative days.</AbstractText>Prospective cohort study.</AbstractText>University-affiliated general hospital.</AbstractText>A total of 21,903 surgery patients treated from January 1, 19... |
28,311 | Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: a clinical trial coordinated by the Eastern Cooperative Oncology Group. | To determine if thalidomide plus dexamethasone yields superior response rates compared with dexamethasone alone as induction therapy for newly diagnosed multiple myeloma.</AbstractText>Patients were randomly assigned to receive thalidomide plus dexamethasone or dexamethasone alone. Patients in arm A received thalidomid... |
28,312 | Follow-up after deep venous thrombosis in azygos continuation. | To determine the sequelae of patients after deep venous thrombosis inpatients with azygos continuation defined as agenesis of the inferior vena cava with collateral flow.</AbstractText>Five patients post deep venous thrombosis in the context of azygos continuation were followed up clinically and with colour duplex ultr... |
28,313 | [Malignancy and thrombosis: a double-sided clinical relationship]. | Venous thromboembolism (VTE) is the second most common cause of mortality in cancer patients and also points towards unfavourable prognosis. In about 10% of patients with idiopathic VTE there is underlying malignancy. However, the efficacy of extensive tumour screening in those patients is not yet established. Numerous... |
28,314 | Venous thromboembolism and fractured neck of femur. | The post-operative incidence of venous thromboembolism (VTE) is high for patients undergoing hip fracture surgery. Proven prophylactic measures are available although underutilized due to concern on post-operative bleeding with use of anticoagulants. This study retrospectively reviewed the clinical incidence of VTE and... |
28,315 | Few predictors of massive deep vein thrombosis. | Factors that predispose to thrombus propagation from the femoropopliteal veins to the pelvic veins are poorly understood. Our goal was to determine whether there are characteristics that identify patients with massive deep vein thrombosis (DVT). We compared the 122 (2.5%) patients presenting with massive DVT (pelvic pl... |
28,316 | D-dimer levels in combination with residual venous obstruction and the risk of recurrence after anticoagulation withdrawal for a first idiopathic deep vein thrombosis. | We assessed the predictive value of D-dimer levels in combination with residual venous obstruction (RVO) for recurrent venous thromboembolism (VTE) in a prospective cohort of outpatients after oral anticoagulant therapy (OAT) suspension for a first episode of idiopathic proximal deep vein thrombosis of the lower limbs ... |
28,317 | Fibrinogen Saint-Germain II: hypofibrinogenemia due to heterozygous gamma N345S mutation. | We have identified a novel heterozygous fibrinogen gamma chain mutation, gammaN345S (Fibrinogen Saint-Germain II), in a subject with hypofibrinogenemia. There was no evidence by mass spectrometry of plasma fibrinogen containing the mutant chain. The hypofibrinogenemia was discovered in a 26-year-old man who experienced... |
28,318 | Homocysteine and thrombosis: from basic science to clinical evidence. | Homocysteine is a sulfhydryl-containing amino acid formed during the metabolism of methionine. Rapidly accumulating evidence links elevated homocysteine levels to thrombosis via several mechanisms such as increased tissue factor expression, attenuated anticoagulant processes, enhanced platelet reactivity, increased thr... |
28,319 | Dural arteriovenous fistulas: unusual access routes in the elderly. | Transvenous embolization is effective in the treatment of an intracranial dural arteriovenous fistula (DAVF). Retrograde venous access to the fistula may be limited by associated sinus thrombosis, as in the two cases here reported. Unusual curative access routes were performed: direct superior ophthalmic vein puncture ... |
28,320 | Coagulation parameters in the patients with Fournier's Gangrene. | In this prospective study, we aimed to determine the coagulation parameters in the patients with Fournier's gangrene.</AbstractText>The study group is consisted of 12 consecutive Fournier's gangrene patients (11 men and 1 woman) and control group is consisted of patients with periurethral abscess (n = 2), scrotal absce... |
28,321 | Functional polymorphisms of FGA, encoding alpha fibrinogen, are associated with susceptibility to venous thromboembolism in a Taiwanese population. | To determine the genetic risk factors for venous thromboembolism (VTE), this study examined 14 genetic variants from 10 hemostatic genes in 186 Taiwanese VTE patients and the same number of matched controls, which demonstrated FGA (encoding alpha fibrinogen) Thr312Ala polymorphism was the only variant significantly ass... |
28,322 | Is there a risk of infertility after inguinal mesh repair? Experimental studies in the pig and the rabbit. | The implantation of a non-absorbable polypropylene mesh during hernia repair causes chronic foreign body reaction involving the surrounding tissue. In case of inguinal hernia repair using mesh techniques, the spermatic cord is potentially affected by this chronic inflammatory tissue remodeling. This effect has been inv... |
28,323 | Catastrophic antiphospholipid antibody syndrome following initiation of hemodialysis. | Antiphospholipid syndrome (APS) is associated with arterial and venous thrombosis, pregnancy morbidity, and thrombocytopenia. Some APS patients develop rapid and disseminated microthrombosis and are known as having catastrophic APS or CAPS. We document here a case of CAPS in a patient who presented with various clinica... |
28,324 | Low frequency of factor V Leiden and prothrombin G20210A mutations in patients with hepatic venous outflow tract obstruction in northern India: a case-control study. | Factor V Leiden (FVL) and prothrombin gene (G20210A) mutations are known to be associated with venous thromboembolism. Several studies have shown an association of these mutations with hepatic venous outflow tract obstruction (HVOTO). We studied the prevalence of these mutations among patients with HVOTO in northern In... |
28,325 | Thrombophilic conditions in non-cirrhotic portal vein thrombosis. | To study the prevalence of thrombophilic conditions in patients with acute and chronic portal vein thrombosis (PVT) and to compare it with those in patients suffering from deep vein thrombosis (DVT) after lower limb arthroplasty and in healthy subjects.</AbstractText>Twenty-six patients with spontaneous PVT (20 chronic... |
28,326 | Nursing interventions in the management of patients with cancer-associated thrombosis. | To provide oncology nurses with an overview of the clinical trial evidence and to help them apply the data to patient management to optimize care and ensure the best possible outcomes.</AbstractText>Primary and tertiary literature and the authors' clinical experience.</AbstractText>Nursing interventions for patients wi... |
28,327 | Use of low-molecular-weight heparins in the treatment and secondary prevention of cancer-associated thrombosis. | To provide oncology nurses with an understanding of the differences between low-molecular-weight heparins and unfractionated heparin, key clinical trial data, and current treatment guidelines.</AbstractText>Primary and tertiary literature and the authors' clinical experience.</AbstractText>The latest American College o... |
28,328 | Therapeutic options for the treatment of cancer-associated thrombosis. | To provide oncology nurses with an understanding of therapeutic options for cancer-associated thrombosis, strategies to prevent recurrence, and practical issues in patient management.</AbstractText>Primary and tertiary literature and the author's clinical experience.</AbstractText>Oncology nurses monitor patients throu... |
28,329 | Abnormal clotting in cancer: an overview of pathophysiology and etiology. | To help oncology nurses become more cognizant of the increased risk cancer patients have for venous thromboembolism due to such factors as chemotherapy and hypercoagulability stemming from the neoplasm itself.</AbstractText>Primary and tertiary literature and the author's clinical experience.</AbstractText>Establishing... |
28,330 | Venous thromboembolism in patients with ischemic and hemorrhagic stroke. | The rates of pulmonary embolism (PE), deep venous thrombosis (DVT), and their combination, venous thromboembolism (VTE), in hospitalized patients with stroke from 1979 to 2003 were determined from the National Hospital Discharge Survey. Of 14,109,000 patients hospitalized with ischemic stroke, PE occurred in 72,000 (0.... |
28,331 | Ion-pairing reversed-phased chromatography/mass spectrometry of heparin. | Heparin and heparin-derived components are widely applied anticoagulant drugs used for amongst other applications medical treatment of deep vein thrombosis and pulmonary embolism. Depolymerisation of native heparin results in complex mixtures of sulfated linear oligosaccharides that are usually not well characterised. ... |
28,332 | Safety and low molecular weight heparin in older people in a hospital with ambulatory care. | To examine major bleeding and mortality rates of low molecular weight heparin (LMWH) and unfractionated heparin (UFH) for patients with pulmonary embolism (PE) and/or deep vein thrombosis (DVT), a retrospective review of the medical records for 286 patients who presented at a local hospital with PE and/or DVT during th... |
28,333 | Expression of the normal factor V allele modulates the APC resistance phenotype in heterozygous carriers of the factor V Leiden mutation. | Functional defects of the protein C pathway, detectable in plasma as activated protein C (APC) resistance, are a prevalent risk factor for venous thrombosis. The factor V (FV) Leiden mutation causes APC resistance by interfering with the APC-mediated inactivation of both FVa and FVIIIa. Co-inheritance of FV Leiden and ... |
28,334 | The post-thrombotic syndrome: risk factors and impact on the course of thrombotic disease. | The post-thrombotic syndrome (PTS) is a frequent complication of deep vein thrombosis (DVT). Patients with recurrent ipsilateral DVT have an increased risk of PTS; other risk factors are unknown.</AbstractText>To establish risk factors of PTS and its impact on venous thrombotic disease.</AbstractText>We prospectively f... |
28,335 | Deep-vein thrombosis rates after major orthopedic surgery in Asia. An epidemiological study based on postoperative screening with centrally adjudicated bilateral venography. | The incidence of postsurgical venous thromboembolism is thought to be low in Asian ethnic populations.</AbstractText>We studied the incidence of deep-vein thrombosis (DVT) in Asian patients undergoing major orthopedic surgery of the lower limbs.</AbstractText><AbstractText Label="PATIENTS/METHODS" NlmCategory="METHODS"... |
28,336 | Successful treatment of cerebral venous thrombosis associated with bilateral internal jugular vein stenosis using direct thrombolysis and stenting: a case report. | Cerebral venous thrombosis (CVT) is not uncommon, but CVT associated with bilateral internal jugular vein stenosis (BIJVS) is rare. Bilateral internal jugular vein stenting is also a rare procedure. We report on a patient with CVT associated with BIJVS, who was treated successfully using direct thrombolysis and bilater... |
28,337 | The impact of catheter-restricted filling with cefotaxime and heparin on the lifespan of temporary hemodialysis catheters: a case controlled study. | Reduction in the rates of major complications such as infection and thrombosis that limit the lifespan of hemodialysis (HD) catheters could conceivably lead to improved survival of "temporary" non-tunneled HD catheters (NTCs). This study was designed to evaluate the impact of the "locking"' of a broad-spectrum antibiot... |
28,338 | Recurrent pulmonary embolism despite inferior vena cava filter placement in patients with the antiphospholipid syndrome. | In patients at risk for pulmonary emboli, consideration is often given to placement of an inferior vena cava (IVC) filter to prevent propagation of a distal thrombus. However, long-term benefits remain controversial, and deep venous thrombosis and IVC thrombosis may result from the procedure itself. Whether a filter if... |
28,339 | Chorioretinal neovascularization after radial optic neurotomy for central retinal vein occlusion. | Radial optic neurotomy was recently introduced for the treatment of central retinal vein occlusion. Two patients developed chorioretinal neovascularization through the radial cut of the optic disc after pars plana vitrectomy, radial optic neurotomy, and endophotocoagulation. Patients undergoing radial optic neurotomy s... |
28,340 | Heparin-induced thrombocytopenia complicated with massive thrombosis of the inferior vena cava after filter placement. | A 45-year-old man presented with deep vein thrombosis of the right leg and bilateral pulmonary embolism. Heparin was administered on the initial one and a half days. On the 3rd day, an inferior vena cava (IVC) filter was placed with a heparin flush, after which massive IVC thrombosis developed. The platelet count was 2... |
28,341 | Impaired ambulatory venous function in lymphedema assessed by near-infrared spectroscopy. | The aim of this study was to investigate venous function in patients with leg lymphedema during exercise using near-infrared spectroscopy (NIRS), compared with that of patients with chronic venous insufficiency (CVI).</AbstractText>Forty-three legs of 33 patients (5 males, 28 females; mean age: 53 years) with leg lymph... |
28,342 | Comparison of two intermittent pneumatic compression systems. A hemodynamic study. | Sequential leg compression has been previously shown to be superior to uniform compression. The aim of our study was to compare the hemodynamic effectiveness of the portable sequential compression device (SCD Express Compression System, Tyco Healthcare Group LP, Mansfield, MA, USA) with a rapid inflation device (VenaFl... |
28,343 | Combined oral contraceptives in women with systemic lupus erythematosus. | Oral contraceptives are rarely prescribed for women with systemic lupus erythematosus, because of concern about potential negative side effects. In this double-blind, randomized, noninferiority trial, we prospectively evaluated the effect of oral contraceptives on lupus activity in premenopausal women with systemic lup... |
28,344 | Enoxaparin for thromboprophylaxis in morbidly obese patients undergoing bariatric surgery: findings of the prophylaxis against VTE outcomes in bariatric surgery patients receiving enoxaparin (PROBE) study. | Obese patients undergoing bariatric surgery are at significant risk for venous thromboembolism (VTE). We performed a multicenter, retrospective survey to evaluate the safety and efficacy of enoxaparin for thromboprophylaxis in patients with morbid obesity undergoing primary bariatric surgery.</AbstractText>From January... |
28,345 | [Novel possibilities of antithrombotic therapy in patients with chronic heart failure].<Pagination><StartPage>93</StartPage><EndPage>98</EndPage><MedlinePgn>93-8</MedlinePgn></Pagination><Abstract><AbstractText>Modern approaches to prevention of venous thromboembolic complications in patients with chronic heart failure... | Modern approaches to prevention of venous thromboembolic complications in patients with chronic heart failure are analyzed in this review which contains results of large studies of low molecular weight heparins. In MEDENOX trial the use of enoxaparin in medical patients was associated with 63% reduction of risk of thro... |
28,346 | C-reactive protein 3' UTR +1444C>T polymorphism in patients with spontaneous venous thromboembolism. | Data on C-reactive protein (CRP) as a risk indicator of venous thromboembolism are conflicting. A recent study reported higher CRP levels in homozygous carriers of a novel CRP gene polymorphism at the 3' UTR (CRP +1444C>T). We investigated, whether homozygosity for CRP +1444C>T is associated with an increased ris... |
28,347 | A unique presentation of antiphospholipid antibody syndrome in pregnancy. | Primary antiphospholipid antibody syndrome (APS) is a protean disease with many manifestations including venous and arterial thrombosis, recurrent foetal loss, preeclampsia, intrauterine growth retardation, cardiac valvular disease, glomerulonephritis, thrombocytopaenia and livedo reticularis. We report an interesting ... |
28,348 | [Outcome of patients with suspected pulmonary thromboembolism and low probability ventilation/perfusion lung scan who receive no long-term anticoagulation]. | To know in our area the security of no long-term anticoagulation in patients with suspected pulmonary thromboembolism (PTE) and a low probability ventilation/perfusion (V/Q) lung scan.</AbstractText>Retrospective review of a series of consecutive outpatients with suspected PTE and a low probability V/Q lung scan, accor... |
28,349 | [Home versus inpatient therapy for deep venous thrombosis. A cost-comparative analysis]. | To compare the home-care management of deep vein thromboses (DVT) by a Home Care Unit (HCU) respect to conventional inpatient treatment.</AbstractText>Twenty-one patients with a doppler-ecography diagnosis of DVT were managed by the HCU during 2002. In 7 out 13 a concomitant diagnosis of pulmonary embolism (PE) was mad... |
28,350 | [Hyperthrombophilia status in a patient without thrombotic events]. | Some case reports have been published in the literature about thrombosis associated with several risk factors, especially in hypercoagulability state. Nevertheless, we have not found any description of a case like this of hyperthrombophilia status without thrombotic events. We present a 75 year old woman who was assess... |
28,351 | [Venous thromboembolic disease in a rural area of Southern Extremadura (Spain)]. | To study the characteristics of the venous thromboembolic disease (VTD) in a rural area of Southern Extremadura (Spain).</AbstractText>Prospective observational study of all patients diagnosed by objective methods of VTD in the only hospital in our area from November 2002 to November 2004.</AbstractText>Seventy-six pat... |
28,352 | The emergency use of recombinant hirudin in cardiopulmonary bypass. 1999. | The most common anticoagulant used for cardiopumonary bypass is heparin. An alternate form of anticoagulant therapy is needed for patients who have immune-mediated heparin-associated thrombocytopenia (HIT). Thrombocytopenia causes bleeding and may lead to serious arterial and venous thrombosis. HIT or heparin-induced t... |
28,353 | The role of ultrasound in renal insufficiency: the essentials. | Sonography is the best screening modality to evaluate patients presenting with renal insufficiency. Ultrasound findings can be normal in patients with renal disease, especially in prerenal azotemia and acute parenchymal renal disease. Echogenic kidneys indicate the presence of parenchymal renal disease; the kidneys may... |
28,354 | Sonography for deep venous thrombosis: current and future applications. | Deep venous thrombosis (DVT) is a one of the most common problems facing the clinician in medicine today. It is often asymptomatic and goes undiagnosed with potentially fatal consequences. Ultrasound has become the "gold standard" in the diagnosis of deep venous thrombosis and with proper attention to technique sensiti... |
28,355 | Thrombolysis of venous and arterial thrombosis by catheter-directed low-dose infusion of tissue plasminogen activator in children. | Thrombolytic therapy is a well-defined treatment option for arterial and venous thrombosis in adults. In contrast, uniform recommendations regarding the indication, route of administration, and dosing of thrombolytic therapy in children are not available. The authors report the successful resolution of bilateral pulmon... |
28,356 | Venous thromboembolism among elderly patients treated with atypical and conventional antipsychotic agents. | Some antipsychotic agents have been indicated as a possible risk factor for venous thromboembolism (VTE) in adult patients with psychiatric disorders. The aim of this study was to estimate the effect of atypical and conventional antipsychotic agents on the risk of hospitalization for VTE among elderly patients.</Abstra... |
28,357 | Management of the relapsed/refractory myeloma patient: strategies incorporating lenalidomide. | The immunomodulatory drug (IMiD) lenalidomide is a more potent immunomodulator than thalidomide with respect to its effects on cytokine modulation and increased T-cell proliferation. Of all the IMiDs, clinical trial data are most mature for lenalidomide. In phase I studies, dose-limiting toxicities of lenalidomide were... |
28,358 | Lenalidomide: patient management strategies. | Experience with thalidomide has underscored the need for diligent monitoring and management of side effects to achieve optimal therapeutic benefit. Initial phase II and III results with lenalidomide, a thalidomide analogue, have confirmed impressive response rates with a significantly more favorable toxicity profile. T... |
28,359 | Venous thromboembolism after spinal cord injury: incidence, time course, and associated risk factors in 16,240 adults and children. | To analyze the incidence of venous thromboembolism (VTE) after spinal cord injury (SCI).</AbstractText>Retrospective cohort analysis of all SCI cases (16,240) in California from 1991 through 2001.</AbstractText>All public hospitals in California.</AbstractText>Subjects (cases) coded as having complete or incomplete SCI... |
28,360 | The role of aspirin in the prevention of thrombotic complications of thalidomide and anthracycline-based chemotherapy for multiple myeloma. | To study the efficacy of daily low-dose aspirin (81 mg orally) in decreasing the incidence of venous thromboembolic events (VTEs) in patients with multiple myeloma receiving pegylated doxorubicin, vincristine, and decreased-frequency dexamethasone, plus thalidomide (DVd-T).</AbstractText>In this phase 2 clinical trial ... |
28,361 | [Tricuspid valve stenosis--an serious complication to Port-a-cath]. | Tricuspid valve stenosis and occlusion of superior vena cava are severe complications to Port-a-cath. In a child with SLE, symptoms started to develop about five to seven years after Port-a-cath insertion and cyclophosphamid injections. The patient developed hepatomegaly with abdominal and venous distension. Open heart... |
28,362 | Arterio-venous dissection after isovolaemic haemodilution in branch retinal vein occlusion: a non-randomised prospective study. | The rationale for this pilot study was to add arterio-venous dissection (AVD) after unsuccessful medical treatment in a well-defined group of patients with branch retinal vein occlusion (BRVO).</AbstractText>In this prospective, interventional case series 35 consecutive patients with a visual acuity (VA) of 0.4 (logMar... |
28,363 | Intrahepatic cholangiocarcinoma presenting as the Budd-Chiari syndrome: a case report and literature review. | Intrahepatic cholangiocarcinoma, an increasingly recognized primary tumour of the liver, is associated with a very poor prognosis. A patient with this tumour who presented with Budd-Chiari syndrome (the first to the authors' knowledge in Western literature and only the third patient overall) secondary to extensive thro... |
28,364 | [Thrombosis and lung cancer]. | Venous thromboembolism (TE) is a frequent occurrence in lung cancer patients and can be precipitated by venous stasis, the activation of clotting cascades by pro-coagulant tumour factors and by vascular injury due to chemotherapy and central venous catheters. Subcutaneous low molecular weight heparin (LMWH) has replace... |
28,365 | Coagulation and splenectomy: an overview. | Venous thromboembolic events, such as pulmonary embolism, deep venous thrombosis, and portal vein thrombosis, have been observed in adult thalassemia patients, mainly in beta-thalassemia intermedia. The clinical findings are consistent with the observation of several alterations that indicate a state of activation of t... |
28,366 | Design and rationale of the MICHELANGELO Organization to Assess Strategies in Acute Ischemic Syndromes (OASIS)-5 trial program evaluating fondaparinux, a synthetic factor Xa inhibitor, in patients with non-ST-segment elevation acute coronary syndromes. | Factor Xa plays a central role in the generation of thrombin, making it a novel target for treatment of arterial thrombosis. Fondaparinux, a synthetic pentasaccharide, is a factor Xa inhibitor, which has been shown to be superior to enoxaparin for the prevention of venous thrombosis. We designed a large, phase III, ran... |
28,367 | Towards evidence-based guidelines for the prevention of venous thromboembolism: systematic reviews of mechanical methods, oral anticoagulation, dextran and regional anaesthesia as thromboprophylaxis. | To assess the benefits in terms of reductions in the risks of deep vein thrombosis (DVT) and of pulmonary embolism (PE), and hazards in terms of major bleeding, of: (i) mechanical compression; (ii) oral anticoagulants; (iii) dextran; and (iv) regional anaesthesia (as an alternative to general anaesthesia) in surgical a... |
28,368 | Hyperhomocysteinaemia: risk of retinal vascular occlusion. | To investigate the possible relationship between hyperhomocysteinaemia and retinal vascular occlusion, we measured plasma homocysteine levels in 25 patients with a history of retinal vascular occlusion in the previous 2 years and in a control group of 24. The difference in mean plasma homocysteine levels was not statis... |
28,369 | Antiphospholipid syndrome and retinal vein occlusion in adults. | Antiphospholipid antibodies may play and important role in the pathogenesis of retinal vascular occlusions; investigated the prevalence among 33 patients with retinal vein and artery occlusions and 80 controls. Prevalence was 33% and 5% respectively. Ophthalmic examination and fluorescein angiography showed that occlus... |
28,370 | [Budd-Chiari syndrome and TIPS--twelve years' experience]. | Massive thrombosis of hepatic veins is clinically the most serious type of Budd-Chiari syndrome (BCS). Ischemic impairment is the basic problem in case of acute or fulminate course of BCS. Restitution of blood drainage within the liver is a key therapeutic approach in such situation. In chronic course of the disease, s... |
28,371 | First-line investigation of acute intracerebral hemorrhage using dynamic magnetic resonance angiography. | To report the initial experience of magnetic resonance (MR) digital subtraction angiography (MR-DSA) in the dynamic assessment of the cerebral circulation in acute non-traumatic intracerebral hemorrhage (ICH).</AbstractText>Twelve patients with acute ICH were investigated within 6 days of the ictus using a dynamic cont... |
28,372 | Hepatic vein stenosis and inferior vena cava stenosis in a patient with chronic obstructive pulmonary disease. | The case is presented of a patient with stenosis of the intrahepatic portion of the inferior vena cava and the terminal part of hepatic veins, a state manifesting itself in ascites resistant to treatment. The case was originally seen as decompensated cirrhosis of the liver. Once properly diagnosed, it was successfully ... |
28,373 | Abulia: no will, no way. | Abulia refers to impaired ability to perform voluntary actions, show initiative, make decisions along with decrease in movements, speech, thought and emotional reactions. We describe here two patients who developed this condition following bilateral insult to different sites in the centromedial core of the brain, the f... |
28,374 | Enoxaparin and heparin comparison of deep vein thrombosis prophylaxis in total hip replacement patients. | We compared the efficacy and safety of standard heparin to that of low molecular weight heparin (Enoxaparin) in 100 hip replacement patients.</AbstractText>A total of 100 patients who underwent total hip replacement surgery were randomised to receive a study medication. Enoxaparin was administered to 50 patients (proph... |
28,375 | Isolated eosinophilic mesenteric vasculitis with extensive thrombosis and splenic infarction in a 13-year-old boy. | There are no generally accepted diagnostic criteria for primary systemic vasculitis, and the application of classification as diagnostic criteria is not feasible and may even be misleading. We report a case of a 13-year-old boy with acute abdomen who was found to have isolated eosinophilic mesenteric vasculitis with ex... |
28,376 | Low molecular weight heparins in cardiovascular medicine. | Cardiovascular diseases are the major cause of morbidity and mortality in the Western countries and their prevalence is increasing in developing world. The final biological evolution of atherosclerotic process, supporting development and progression of cardiovascular diseases, is thrombosis. In the most recent years se... |
28,377 | Manifestations of chronic disease during pregnancy. | Physiologic changes of pregnancy include insulin resistance, thrombophilia, immunosuppression, and hypervolemia. These changes may herald the development of disease in later life.</AbstractText>To summarize current evidence on how pregnancy reveals risk of chronic disease.</AbstractText>MEDLINE was searched for article... |
28,378 | The anti-angiogenesis agent, AG-013736, has minimal activity in elderly patients with poor prognosis acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). | AG-013736 is an oral anti-angiogenesis agent with activity against a variety of receptor tyrosine kinases, including VEGFR-1, VEGFR-2, VEGFR-3, c-kit, and PDGFR-beta. A phase 2 study was conducted in patients with poor prognosis AML or MDS. Twelve patients (six AML; six MDS) were treated with AG-013736 at a dose of 10m... |
28,379 | Association of 4G/5G polymorphism in PAI1 promoter with PAI1 level in deep vein thrombosis. | To reveal the association of 4G/5G polymorphism in the promoter region of the plasminogen activator inhibitor 1 gene (PAI1) with plasma PAI1 level in deep vein thrombosis (DVT) in Chinese Han ethnic group.</AbstractText>One hundred and twenty Chinese DVT patients and 120 healthy controls were recruited. The PAI1 promot... |
28,380 | Venous thromboembolic prophylaxis after elective total hip arthroplasty. | Elective total hip arthroplasty is a common orthopaedic procedure that has been proven to relieve pain and reliably improves the quality of life of its patients. However, patients having a total hip arthroplasty are among those at greatest risk for venous thromboembolic disease. Therefore, most orthopaedic surgeons use... |
28,381 | Regional anesthesia in hip surgery. | Historically, general anesthesia has been the "gold standard" for surgeons and patients when major hip surgery is being done. The recent introductions of improved techniques and catheters for continuous peripheral nerve blocks have made regional anesthesia more attractive to patients and surgeons. We focus on current t... |
28,382 | The John Charnley Award: prevention of readmission for venous thromboembolic disease after total hip arthroplasty. | Venous thromboembolic disease remains the most common reason for readmission after total hip arthroplasty. Prospective analysis of screening contrast venography was done from 1984 to 2003 in 1972 patients having elective total hip arthroplasty. Patients with deep venous thrombosis or pulmonary embolism received warfari... |
28,383 | The John Charnley Award: heritable thrombophilia and development of thromboembolic disease after total hip arthroplasty. | We retrospectively assessed whether heritable thrombophilia-hypofibrinolysis was more common in patients developing venous thromboembolism after total hip replacement than among control patients who did not develop venous thromboembolism, as an approach to better identify causes of venous thromboembolism after total hi... |
28,384 | Branch retinal artery occlusion combined with branch retinal vein occlusion in a patient with hepatitis C treated with interferon and ribavirin. | To report a case of a combined branch retinal artery and vein occlusion in a patient with hepatitis C treated with interferon and ribavirin.</AbstractText>A 29-year-old man with a 1-week history of sudden visual field defect and decrease of central visual acuity was examined.</AbstractText>Ophthalmoscopy and fluorescei... |
28,385 | Intravitreal triamcinolone acetonide for treatment of central retinal vein occlusion. | To evaluate the effect of intravitreal triamcinolone acetonide on visual acuity and intraocular pressure in patients with central retinal vein occlusion.</AbstractText>This prospective comparative non-randomized clinical interventional study included 32 patients (33 eyes) with central retinal vein occlusion. The study ... |
28,386 | Cerebral venous sinus thrombosis presenting with excessive subarachnoid hemorrhage in a 14-year-old boy. | Cerebral venous thrombosis presenting with subarachnoid hemorrhage (SAH) is very rare. We report a case of cerebral venous sinus thrombosis as an initial manifestation of SAH. A 14-year-old boy was admitted with progressive headache, nausea, vomiting, diplopia, and gait disturbance. Cerebral computed tomography scan sh... |
28,387 | Thrombosis of the palmar digital veins: a report of 6 cases and a review of the literature. | Our experience in 6 cases of thrombosis of the palmar digital veins is presented and an additional 20 from the world literature are reviewed. All our patients were female and suffered from a tender, bluish nodule on the palmar aspect of a digit at or distally to the proximal interphalangeal joint. In the first 2 cases,... |
28,388 | Anticoagulation in ischemic stroke: opportunities in arterial disease. | In the acute phase of ischemic stroke, there is no evidence that anticoagulants provide any benefit in terms of death or dependency. A small reduction in the incidence of recurrent stroke is offset by an equally small increase in intracranial hemorrhage (ICH). In the secondary prevention of stroke, in patients with tra... |
28,389 | Venous thromboembolism associated with hip and knee replacement over a ten-year period: a population-based study. | This population-based study investigated the incidence and trends in venous thromboembolic disease after total hip and knee arthroplasty over a ten-year period. Death or readmission for venous thromboembolic disease up to two years after surgery for all patients in Scotland was the primary outcome. The incidence of ven... |
28,390 | What progress has been made in surgical management of patients with astrocytoma and oligodendroglioma in Australia over the last two decades? | Most primary brain cancers are associated with a dismal prognosis because of their aggressive behaviour and high mortality. Surgical resection with adjuvant radiotherapy is a major treatment for these cancers but little has been published about their surgical management in Australia.</AbstractText>To determine changes ... |
28,391 | Perioperative management of special populations: obesity. | Surgeons and hospitals must be aware of the special considerations for treating obese patients. Obesity involves increased incidence of several comorbidities, such as coronary heart disease and hyper-tension, which increase perioperative risk. Obesity has been identified as an independent risk factor for surgical site ... |
28,392 | Thrombosis and coagulation: operative management of the anticoagulated patient. | The surgical management of the anticoagulated patient requires an understanding of the fundamentals of blood thrombosis, the mechanisms that enable anticoagulants to work, and the indications for anticoagulation. As percutaneous cardiac and peripheral procedures become increasingly sophisticated, we can expect to encou... |
28,393 | Thrombosis and coagulation: deep vein thrombosis and pulmonary embolism prophylaxis. | Venous thromboembolism (deep venous thrombosis and pulmonary embolism, VTE) is a common complication in surgical patients and is the primary cause of preventable deaths in hospitalized patients. Despite well-known risk factors, VTE prophylaxis is frequently not practiced according to recommended guidelines. Patients ca... |
28,394 | Multiorgan failure and antiphospholipid antibodies: the catastrophic antiphospholipid (Asherson's) syndrome. | A review of 250 patients with the catastrophic antiphospholipid (Asherson's) syndrome (CAPS) taken from the web site organized by the Europhospholipid Group (http://www.med.ub.es/MIMMUN/FORUM/CAPS.HTM) is presented in this paper. A short historical overview of the antiphospholipid syndrome (APS) is followed by a descri... |
28,395 | [Diabetic neuroarthropathy in acute phase: a diagnostic dilemma. Two cases and bibliographic review]. | Charcot's neuroarthropathy is a progressive deterioration of bones and joints, mainly the ankle and foot of the diabetic patients suffering severe neuropathy. Its pathogeny is not well known, although mechanical, vascular and neurological factors are thought to be involved, generally with a precipitating minor traumati... |
28,396 | [New strategies in the secondary prevention of relapsing venous thromboembolism]. | Treatment of venous thromboembolism includes an acute phase treatment, followed by a secondary prophylaxis period. Oral anticoagulants have been the usual treatment for secondary prophylaxis of VTE. However, some issues regarding oral anticoagulant treatment (OAT), such as length or intensity are controversial. The app... |
28,397 | [Effects of transcatheter closure of perimembranous ventricular septal defects: intermediate and long-term follow-up of 68 cases]. | To evaluate the curative effects of transcatheter closure on perimembranous ventricular septal defects (PMVSDs) using unbalanced Amplatzer asymmetric ventricular septal defect occluder (AAVSDO).</AbstractText>The data of 68 patients of PMVSDs with a diameter of 6.7 mm (3 to 12 mm) and the diameter of ventricular septal... |
28,398 | Successful renal transplantation in the right iliac fossa 2 years after serious deep venous thrombosis in a patient with systemic lupus erythematosus. | Deep venous thrombosis (DVT) possibly occurs in the perioperative period, and induces serious complications such as a pulmonary embolism. On the other hand, allograft renal vein thrombosis leads to a high incidence of graft loss. We experienced a case in which a serious DVT occurred prior to renal transplantation; howe... |
28,399 | [Severe bilateral visual loss as the presenting sign of cerebral venous sinus thrombosis: case report]. | Our purpose is to report a case of cranial venous thrombosis causing pseudotumor syndrome, where the principal clinical manifestation was severe bilateral vision loss. A 24-year-old man presented with severe bilateral vision loss, transient obscuration of vision, headache, bilateral papilledema and constricted visual f... |
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