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31,400 | A new case of fatal pulmonary thromboembolism associated with prolonged sitting at computer in Korea. | A newly reported, variant form of venous thromboembolism (VTE), named as "eThrombosis", occurred in a patient who maintained a prolonged sitting position at a computer. The patient fortunately recovered from the disease through early diagnosis and treatment. Recently however, the author experienced a new case of a 24-y... |
31,401 | Polytetrafluoroethylene-covered nitinol stent-graft for transjugular intrahepatic portosystemic shunt creation: 3-year experience. | To prospectively evaluate the use of a recently developed expanded polytetrafluoroethylene (PTFE)-covered nitinol stent-graft in preventing the need for repeated intervention after transjugular intrahepatic portosystemic shunt (TIPS) creation.</AbstractText>Fifty-three consecutive patients underwent TIPS procedures bet... |
31,402 | Septic pelvic thrombophlebitis and preeclampsia are related disorders. | To elicit factors associated with the postpartum development of septic pelvic thrombophlebitis in a single large referral tertiary patient population.</AbstractText>A nine-year single institution retrospective case review of all patients with enigmatic fever and septic pelvic thrombophlebitis was analyzed.</AbstractTex... |
31,403 | Current perspectives on the treatment of venous thromboembolism: need for effective, safe and convenient new antithrombotic drugs. | Treatment of venous thromboembolism (VTE) has evolved significantly over the last decade. Low-molecular-weight heparins have largely replaced unfractionated heparin in the treatment of deep-vein thrombosis (DVT) but the majority of patients with pulmonary embolism (PE) continue to be treated with unfractionated heparin... |
31,404 | Lower limb venous haemodynamic impairment on dependency: quantification and implications for the "economy class" position. | The role of stasis in venous disease is undisputed, yet surprisingly, its haemodynamic quantitation remains largely undefined. We investigated the phenomenon of venous stasis in the lower limb upon sitting and standing and project its implications to economy class aircraft passengers. 26 normal limbs, 13 subjects, age ... |
31,405 | Prospective evaluation of coagulation activation in pregnant women receiving low-molecular weight heparin. | Pregnancy is a major risk factor for venous thromboembolism (VTE), and low-molecular weight heparin (LMWH) seems to be safe and effective in pregnant women. Normal pregnancy is accompanied by a state of hypercoagulability, indicated by an increase in markers of coagulation activation. In a prospective cohort study, we ... |
31,406 | Orally administered heparins prevent arterial thrombosis in a rat model. | Our previous studies demonstrated that orally administered heparins prevent thrombosis in a rat jugular vein thrombosis model, where bovine unfractionated heparin (UFH) and the low molecular weight heparin tinzaparin reduced thrombotic incidence by 50% at 7.5 and 0.1 mg/kg, respectively. Our objectives were to determin... |
31,407 | Contribution of polymorphisms in the endothelial protein C receptor gene to soluble endothelial protein C receptor and circulating activated protein C levels, and thrombotic risk. | Endothelial cell protein C receptor (EPCR) enhances the generation of activated protein C (APC) by the thrombin-thrombomodulin complex. A soluble form of EPCR (sEPCR), which is generated by metalloprotease activity, is present in plasma. The distribution of sEPCR levels in healthy populations is bimodal. Previously, we... |
31,408 | Association after linkage analysis indicates that homozygosity for the 46C-->T polymorphism in the F12 gene is a genetic risk factor for venous thrombosis. | In a family-based study called GAIT (Genetic Analysis of Idiopathic Thrombophilia) that included a genome-wide scan we demonstrated that a polymorphism (46C-->T) in the F12 locus jointly influences variability of plasma (Factor XII) FXII levels and susceptibility to thrombotic disease. It then became germane to dete... |
31,409 | Generating pre-test probabilities: a neglected area in clinical decision making. | To assess the accuracy and variability of clinicians' estimates of pre-test probability for three common clinical scenarios.</AbstractText>Postal questionnaire survey conducted between April and October 2001 eliciting pre-test probability estimates from scenarios for risk of ischaemic heart disease (IHD), deep vein thr... |
31,410 | Sepsis and elevated liver enzymes in a patient with inflammatory bowel disease: think of portal vein thrombosis. | A 42-year old man, 1 year previously diagnosed with ulcerative colitis after an emergency subtotal colectomy with formation of an ileostomy because of severe colitis with perforation, was admitted with sepsis and jaundice. The liver enzymes were elevated and blood cultures were positive for Streptococcus milleri. Magne... |
31,411 | Thrombocytopenia due to acute venous thromboembolism and its role in expanding the differential diagnosis of heparin-induced thrombocytopenia. | Thrombocytopenia is an uncommon but serious consequence of heparin administration. Occasionally patients with massive acute venous thromboembolism (VTE) will develop thrombocytopenia. As heparin or some thrombin inhibitor is strongly indicated in acute VTE, it is important to distinguish this event from heparin-induced... |
31,412 | MTHFR C677T polymorphism and its relation to ischemic stroke in the Black Sea Turkish population. | The MTHFR C677T mutation has been shown to be associated with venous thrombosis. The role of this mutation in ischemic stroke is unclear. We investigated whether the MTHFR mutation is a risk factor for patients with ischemic stroke in the Black Sea Turkish population or not. We analyzed 30 patients (19 male, 11 female)... |
31,413 | R147W mutation of PROC gene is common in venous thrombotic patients in Taiwanese Chinese. | We analyzed the genetic defects of 21 unrelated patients with venous thrombosis in whom hereditary protein C deficiency was diagnosed. Eleven mutations were detected in 18 families, while no mutation was detectable in the other three families. Among these mutations, a common genetic mutation of protein C (PROC) gene re... |
31,414 | Catastrophic heparin-induced thrombocytopenia/thrombosis syndrome related to the use of a Port-A-Cath in a breast cancer patient receiving chemotherapy. | Heparin-induced thrombocytopenia and thrombosis (HIT/T) syndrome is usually triggered by an immune response after repeated administration of heparin. The syndrome is strongly associated with limb deep vein thrombosis and is potentially life-threatening if unrecognized. We describe the case of a patient with compartment... |
31,415 | Seasonal variation in the occurrence of deep vein thrombosis. | The occurrence of several adverse cardiovascular events, eg, myocardial infarction and stroke, is not randomly distributed over time, but shows definite seasonal patterns. The temporal pattern for pulmonary embolism (PE) is known, whereas the data concerning deep vein thrombosis (DVT) are not conclusive. The aim of our... |
31,416 | Analysis of outpatient surgery center safety using an internet-based quality improvement and peer review program. | Assessing the quality of care delivered in office-based outpatient surgery centers is difficult because formerly there was no central data collection system. The American Association for Accreditation of Ambulatory Surgery Facilities (AAAASF), in its ongoing effort to assess and improve patient care, has developed an I... |
31,417 | Sudden death of a patient with primary hypereosinophilia, colon tumours, and pulmonary emboli. | A 33 year old man was admitted to hospital six days after the onset of abdominal pain. There was hypereosinophilia, but the cause could not be identified (primary hypereosinophilia). The hypereosinophilia, high C reactive protein concentration, and gastrointestinal symptoms were alleviated by corticosteroid treatment. ... |
31,418 | Prevention of pulmonary embolism by combined modalities of thromboprophylaxis and intensive surveillance protocol. | Deep vein thrombosis (DVT) is a known complication in neurosurgical patients. The protocols for the prevention of DVT and pulmonary embolism (PE) are not applied universally. Our goal was to review the incidence of DVT and PE in neurosurgical intensive care units (NSICUs) and to compare it with the incidence of DVT and... |
31,419 | Pharmacologic and clinical characteristics of thrombolytic agents. | Arterial and venous thromboembolic events, including myocardial infarction, ischemic stroke, peripheral arterial thrombosis, deep venous thrombosis, and pulmonary embolism are common potentially life-, organ-, and limb-threatening vascular diseases. Anticoagulant therapy is recommended in these settings to prevent furt... |
31,420 | Venous thromboembolism in oncology. | Thromboembolic events represent well-recognised complications of neoplastic disease contributing, in a significant manner, to the morbidity and mortality from cancer. The close relationship between the activation of blood coagulation and tumor growth is known since 1865, when Armand Trousseau first described the clinic... |
31,421 | Skin reactions due to low molecular weight heparin in pregnancy: a strategic dilemma.<Pagination><StartPage>163</StartPage><EndPage>165</EndPage><MedlinePgn>163-5</MedlinePgn></Pagination><Abstract><AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">Heparin-induced allergic reactions may cause problems if hepar... | Problems of strategy and policy of surgical treatment of acute thrombophlebitis in the territory of saphena magna vein are discussed. Results of urgent radical combined venectomy in 76 patients are presented. A gas technique of subfascial dissection of perforant veins (SEPS) was used in 52 patients for the first time b... |
31,422 | Surgical disobliteration of postthrombotic deep veins--endophlebectomy--is feasible. | Partial obstruction of postthrombotic veins is caused by endovenous scar tissue, which creates synechiae and septae that narrow and sometimes block the lumen. We have performed surgical disobliteration, or endophlebectomy, of chronically obstructed venous segments during various kinds of deep venous reconstructions to ... |
31,423 | Can low molecular weight heparin replace unfractionated heparin during peripheral arterial reconstruction? An open label prospective randomized controlled trial. | This study was undertaken to evaluate the effect of low molecular weight heparin (LMWH) compared with unfractionated heparin (UFH) on the rate of occlusion and bleeding during peripheral vascular surgery.</AbstractText>The study was an open label, prospective, randomized trial, carried out by 20 Swedish surgical and va... |
31,424 | Iliac vein compression in an asymptomatic patient population. | May-Thurner syndrome is a well-recognized anatomic variant that is associated with the development of symptomatic acute venous thrombosis of the left iliac vein. However, the natural frequency of compression of the left iliac vein and its clinical significance in asymptomatic disease has not been established. Therefore... |
31,425 | Iatrogenic operative injuries of abdominal and pelvic veins: a potentially lethal complication. | Epidemiologic studies of vascular injuries are usually limited to those caused by trauma. The purpose of this study was to review the management and clinical outcome in patients with operative injuries to abdominal and pelvic veins.</AbstractText>Clinical data and outcome in all patients with iatrogenic venous injuries... |
31,426 | Polycythemia vera in a child following treatment for acute lymphoblastic leukemia. | Polycythemia vera (PV), a hematologic stem cell disorder characterized by predominant erythroid proliferation, is extremely rare in childhood. Some PV patients develop acute leukemia, especially acute myelogenous leukemia, but cases of PV occurring after treatment of acute leukemia are rare. The authors describe a girl... |
31,427 | Multirow CT in the follow-up of pancreas transplantation. | Isolated pancreas or combined kidney-pancreas transplantation represents the only therapeutic weapon for complete resolution of type I diabetes mellitus. The purpose of the present study was to investigate the role of multirow CT in the follow-up of these patients.</AbstractText>Thirty patients who underwent isolated (... |
31,428 | Role of interventional radiology in the management of vascular complications after liver transplantation. | The purpose of this study is to review the role of the percutaneous interventional procedures in the treatment of vascular complications after orthotopic liver transplantations (OLT). Vascular complications, such as arterial stenosis and venous thrombosis, which occur in approximately 1% to 10% of liver transplant pati... |
31,429 | Regional differences in rates of diagnosis and mortality of pulmonary thromboembolism. | The rates of diagnosis of deep venous thrombosis, pulmonary embolism (PE), and venous thromboembolism (PE and/or deep venous thrombosis) and the mortality rate of PE in hospitalized patients were evaluated in 4 regions of the United States. Data are from the National Hospital Discharge Survey and the United States Bure... |
31,430 | Retrospective database analysis of the prevention of venous thromboembolism with low-molecular-weight heparin in acutely III medical inpatients in community practice. | Clinical trials have demonstrated that prophylaxis with low-molecular-weight heparin reduces the occurrence of venous thromboembolism (VTE) among acutely ill medical inpatients in the experimental setting.</AbstractText>The goal of this retrospective database analysis was to examine the outcomes of low-molecular-weight... |
31,431 | Bird's nest filter causing symptomatic hydronephrosis following transmural penetration of the inferior vena cava. | We report a case of symptomatic hydronephrosis caused by transcaval penetration of a Bird's Nest filter. Perforation of the wall of the inferior vena cava (IVC) following insertion of a caval filter is a well-recognized complication. Whilst two cases of hydronephrosis have been described with Greenfield filters, no cas... |
31,432 | Guenther tulip filter retrieval from a left-sided inferior vena cava. | Optional (retrievable) inferior cava filters (IVC) may have advantages over permanent filters in a certain subset of patients, especially in view of recent concerns about the long-term thrombotic complications of the latter. Retrieval of the Guenther Tulip Filter (GTF), an optional filter, has been reported in a total ... |
31,433 | Eversion thromboendovenectomy in organized portal vein thrombosis during liver transplantation. | Portal thrombosis is no longer considered a contraindication for transplantation because of the technical experience acquired in the field of liver transplantation and the development of various surgical techniques. All the same, the results obtained in portal thrombosis patients are at times suboptimal, and the surgic... |
31,434 | Intracranial pseudoaneurysm due to rupture of a saccular aneurysm mimicking a large partially thrombosed aneurysm ("ghost aneurysm"): radiological findings and therapeutic implications in two cases. | Intracranial pseudoaneurysm formation due to ruptured non-traumatic saccular aneurysm is extremely rare. We experienced two cases of large pseudoaneurysm formation due to rupture of a saccular aneurysm. The neuroradiological ghost-like appearance of the aneurysms led to misdiagnoses as large partially thrombosed aneury... |
31,435 | [Modern anticoagulation. Problems of the proven, hope for the new]. | Anticoagulation is highly effective in the prevention and treatment of venous thromboembolism (VTE). Since decades, vitamin K antagonists (VKA) were the only available oral anticoagulants. Even though VKA are very effective, they have numerous practical problems: Due to their narrow therapeutic window, highly variable ... |
31,436 | Maternal brain death: medical, ethical and legal issues. | We present the case of a pregnant woman who experienced a cerebral venous sinus thrombosis resulting in brain death at 13 weeks gestation. We discuss the management of the mother and foetus following this tragic event. We also discuss the complex medical, legal and ethical issues that arose following maternal brain dea... |
31,437 | Best evidence topic reports. Safety of inferior vena cava filters as primary treatment for proximal deep vein thrombosis. | A short cut review was carried out to establish whether inferior vena cava filters were better than standard anticoagulation therapy in reducing pulmonary emboli in patients with proximal vein lower limb DVTs. Altogether 463 papers were found using the reported search, of which one presented the best evidence to answer... |
31,438 | Partial thrombosis of an idiopathic azygos vein aneurysm. | Aneurysms of the azygos vein are often asymptomatic, detected on a chest radiograph simulating paratracheal mass. When the aneurysm is totally thrombosed, it is impossible to distinguish it from another cause of mediastinal mass. A case is presented in which partial thrombosis of the aneurysm and communication with the... |
31,439 | Preparation and characterization of [99TcO] apcitide: a technetium labeled peptide. | [99mTcO] apcitide (99mTcO(P246)), the technetium complex of the 13 amino acid, apcitide, cyclo-(D-Tyr-Apc-Gly-Asp-Cys)-Gly-Gly-Cys(Acm)-Gly-Cys(Acm)-Gly-Gly-Cys-NH2, where Apc is L-[S-(3-aminopropyl)]cysteine (an arginine mimetic) and Acm is the acetamidomethyl protecting group, has high affinity and selectivity for th... |
31,440 | Branch retinal vein occlusion treated by intravitreal triamcinolone acetonide. | To evaluate the effect of intravitreal triamcinolone acetonide on visual acuity in branch retinal vein occlusion.</AbstractText>The prospective comparative nonrandomized clinical interventional study included 28 patients (28 eyes) with branch retinal vein occlusion. The study group consisting of 10 consecutive patients... |
31,441 | [Thromboembolic events related to travel, with the train too]. | The risk of thromboembolic events related to travel is not exclusively due to air travel. We report the case of a patient who presented pulmonary embolism after prolonged train travel.</AbstractText>An 82 Year-old patient had a significant past history of ischemic heart disease. He traveled by train, in a sitting posit... |
31,442 | [Impact of HRT on the arterial carotid vascular tree]. | Hormone replacement therapy (HRT) and arterial impact, this is a controversial subject since it is a large field that needs weeding, a theme in which new questions are raised by the cross-results of various studies conducted, and in which doubt is perhaps one of, or even the only, certitude that all the various special... |
31,443 | Neoadjuvant chemotherapy in squamous cell carcinoma of the esophagus using low dose continuous infusion 5-fluorouracil and cisplatin: results of a prospective study. | Surgery is the treatment of choice for localized esophageal squamous cell carcinoma (ESCC). Despite curative surgical resection, the majority of patients develop local and systemic recurrence with poor 5-year survival.</AbstractText>To study the role of low dose continuous infusion (CI) 5-fluorouracil (5-FU) and cispla... |
31,444 | Deep vein thrombosis resolution is modulated by monocyte CXCR2-mediated activity in a mouse model. | To determine the role of CXCR2, the receptor for cysteine-X-cysteine (CXC) chemokines, and its primary effector cell, the neutrophil (PMN), on deep venous thrombosis (DVT) resolution.</AbstractText>DVT in BALB/c, anti-CXCR2 antibody-treated, and BALB/c CXCR2(-/-) mice were created by infrarenal inferior vena cava (IVC)... |
31,445 | [The efficacy of arteriovenous adventitial sheathotomy for macular edema in branch retinal vein occlusion]. | To examine the efficacy of arteriovenous adventitial sheathotomy (or arteriovenous decompression) for macular edema (ME) in branch retinal vein occlusion (BRVO).</AbstractText>Eighty-three patients (83 eyes) who had ME in BRVO for 26 weeks or less underwent pars plana vitrectomy and internal limiting membrane dissectio... |
31,446 | Nursing initiatives for deep vein thrombosis prophylaxis. Pragmatic timing of administration. | This review explores the importance of the course of time in the development of deep vein thrombosis and its connection to prophylaxis in total hip replacement, emphasizing the impact on nursing practice. It examines the application of expanded use of low-molecular-weight heparin as an effective option versus warfarin.... |
31,447 | [Pulmonary venous thrombosis and neoplasia related cerebrovascular ischaemic events]. | Stroke in patients with malignant tumor are associated with various aetiologies. We report a case of lung adnocarcinoma with pulmonary vein thrombosis appending into the left atrial revealed by multiple cerebral infarcts. |
31,448 | [Cerebral venous thrombosis presenting as subarachnoid hemorrhage]. | Headache of subacute onset, associated with other signs of increased intracranial pressure, represents the most frequent symptom of cerebral thrombophlebitis. We report a case of subarachnoid hemorrhage as a rare presentation of cerebral thrombophlebitis. Unfractionated intravenous heparin treatment resulted in resolut... |
31,449 | [Dural arteriovenous fistula. A rare cause of treatable dementia]. | Dural fistulas are acquired arteriovenous shunts, accounting for 10-15p.cent of cerebrovascular malformations. Symptoms are commonly tinnitus or intracranial hemorrhage. Rarely, patients with dural fistulas can present with rapid cognitive impairment. We report two women with rapidly evolving dementia. Cerebral angiogr... |
31,450 | Clinical and angiographic features in nasal branch retinal vein occlusion. | To analyse the epidemiological and clinical characteristics of nasal branch retinal vein occlusion (NBRVO).</AbstractText>Patients affected by branch retinal vein occlusion observed in the out-patient departments of the Eye Clinic of Trieste between January 1995 and January 1999 were enrolled.</AbstractText>Out of 144 ... |
31,451 | SSR182289A enhances thrombolysis induced by fibrinolytic agents in rabbit models of venous and arterial thrombosis. | The purpose of this work was to investigate whether thrombolysis induced by recombinant tissue plasminogen activator (rt-PA) or streptokinase (SK) was enhanced in different rabbit models of thrombolysis by SSR182289A, a novel synthetic direct thrombin inhibitor which has been shown to possess potent antithrombotic prop... |
31,452 | Activation of innate immunity in patients with venous thrombosis: the Leiden Thrombophilia Study. | Previous studies have suggested that levels of inflammatory mediators are risk indicators for venous thrombotic disease. We have sought to confirm and extend these findings by measuring plasma tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, IL-6, IL-8, IL-10 and IL-12p70 levels in a case-control study for ve... |
31,453 | Tissue-type plasminogen activator: a historical perspective and personal account. | Over the past two decades tissue-type plasminogen activator (t-PA), the main physiological plasminogen activator, has been developed as a fibrin-specific thrombolytic agent for the treatment of various thromboembolic diseases. Milestones in this development include: first purification of human t-PA from uterine tissue,... |
31,454 | Unusual hepatic-portal-systemic shunting demonstrated by Doppler sonography in children with congenital hepatic vein ostial occlusion. | This report describes unusual changes in the hepatic vasculature in 3 children presenting with upper gastrointestinal hemorrhage.</AbstractText>The study included 3 children (ages 5-8 years) who presented with hematemesis. All had mild hepatosplenomegaly and normal liver function. Esophageal varices were demonstrated i... |
31,455 | [Genetic risk factors of venous thromboembolism]. | Up to date several hereditary disorders have been identified as prothrombic risk factors. The most common inherited thrombotic disorders include activated protein C resistance (factor V Leiden), prothrombin G20210A mutation, hyperhomocysteinemia, deficiencies of protein C, protein S, antithrombin III, and thrombomoduli... |
31,456 | Dehydration and venous thromboembolism after acute stroke. | Although it is widely assumed that dehydration predisposes to venous thromboembolism (VTE), there are no clinical studies to support this.</AbstractText>To evaluate the relationship between biochemical indices of dehydration and VTE after acute ischaemic stroke (AIS).</AbstractText>Prospective observational study.</Abs... |
31,457 | Cost-effectiveness of combination thromboembolism prophylaxis in gynecologic oncology surgery. | To compare the cost-effectiveness of external pneumatic compression devices with and without the addition of low-molecular-weight heparin for the prevention of deep vein thrombosis in high-risk surgical patients with gynecologic cancer.</AbstractText>A Markov decision analytic model was used to estimate the costs and o... |
31,458 | Sex and gender issues and venous thromboembolism. | At least 250,000 episodes of VTE leading to hospitalization or death are estimated to occur in the United States each year. A number of clinical and demographic risk factors for VTE are recognized,with the latter including both age and race. Overall,the incidence of VTE does not appear to vary significantly by sex, as ... |
31,459 | The 894 G > T variant of endothelial nitric oxide synthase (eNOS) increases the risk of recurrent venous thrombosis through interaction with elevated homocysteine levels. | Venous thrombosis is a multicausal disease involving both genetic as well as acquired risk factors. Hyperhomocysteinemia is associated with a 2-fold increased risk of recurrent venous thrombosis (RVT). Recently, the 894 G > T variant of endothelial nitric oxide synthase (eNOS) was postulated to be associated with hy... |
31,460 | Comparison of 1 month with 3 months of anticoagulation for a first episode of venous thromboembolism associated with a transient risk factor. | The risk of recurrence is lower after treatment of an episode of venous thromboembolism associated with a transient risk factor, such as recent surgery, than after an episode associated with a permanent, or no, risk factor. Retrospective analyses suggest that 1 month of anticoagulation is adequate for patients whose ve... |
31,461 | A prospective, longitudinal study of central venous catheter-related deep venous thrombosis in boys with hemophilia. | Central venous catheters (CVCs) are often inserted into boys with hemophilia to secure venous access for factor prophylaxis and immune tolerance induction therapy. Complications associated with CVCs include catheter-related infections, local hemorrhage, and mechanical failure. Less frequently reported is CVC-related de... |
31,462 | Familial segregation of venous thromboembolism. | Venous thromboembolism (VTE) is postulated as a complex disease, but the heritability and mode of inheritance are uncertain.</AbstractText>To determine if VTE (i) segregates in families; (ii) is attributable to inheritance, shared environment, or both; and (iii) the possible mode of inheritance.</AbstractText>In a fami... |
31,463 | [Results and surgical complications of pancreas transplantation with enteric exocrine drainage]. | The objective of this study was to evaluate the results and surgical complications of total pancreas transplantation with enteric exocrine drainage since the beginning of our experience with this type of transplantation.</AbstractText>From November 1999 to December 2002, 62 total pancreas transplantations were performe... |
31,464 | Deep vein thrombosis following hip fracture and prevalence of hyperhomocysteinaemia in the elderly. | The prevalence of deep vein thrombosis (DVT) in the West is reported to be as high as 50% after hip surgery. A study performed 14 years ago showed the incidence in Singapore to be <10%. Lately, some case-control and cross-sectional studies have suggested hyperhomocysteinaemia as an independent risk factor for DVT. T... |
31,465 | Thrombosis in inferior vena cava (IVC) due to intra-cystic hemorrhage into a hepatic local cyst with autosomal dominant polycystic kidney disease (ADPKD). | A 76-year-old man with autosomal dominant polycystic kidney disease (ADPKD) was admitted complaining of severe edema of bilateral lower extremities. Computed tomography (CT) of his abdomen revealed an enlarged hepatic cyst with intra-cystic hemorrhage, and massive thrombosis in the inferior vena cava (IVC). The extrins... |
31,466 | Vascular complications of pancreas transplantation. | The purpose of our study was to focus on the early diagnosis and treatment of vascular complications after simultaneous pancreas-kidney (SPK) transplantation. Description of the technique for salvage of the graft after venous thrombosis (VT) is also provided.</AbstractText>From July 1994 to December 2002, 14 patients o... |
31,467 | Catheter-related focal FDG activity on whole body PET imaging. | Whole body FDG positron emission tomography (PET) scan is increasingly being used in the management of a variety of cancers and infections. Cancer patients and other very sick patients have central venous catheters, which could be associated with common complications like thrombosis and infections. We describe catheter... |
31,468 | Reconstruction after soft tissue sarcoma resection in the setting of brachytherapy: a 10-year experience. | Management of recurrent soft tissue sarcomas often involves surgical resection and adjuvant brachytherapy. This study reviews our experience in the management of these patients and proposes a logical approach toward reconstruction. All patients who underwent soft tissue sarcoma resection, adjuvant brachytherapy, and so... |
31,469 | Detection of genomic polymorphisms associated with venous thrombosis using the invader biplex assay. | A multi-site study to assess the accuracy and performance of the biplex Invader assay for genotyping five polymorphisms implicated in venous thrombosis was carried out in seven laboratories. Genotyping results obtained using the Invader biplex assay were compared to those obtained from a reference method, either allele... |
31,470 | D-dimer for the exclusion of acute venous thrombosis and pulmonary embolism: a systematic review. | Despite extensive literature, the diagnostic role of d-dimer for deep venous thrombosis (DVT) or pulmonary embolism (PE) remains unclear, reflecting multiple d-dimer assays and concerns about differing sensitivities and variability.</AbstractText>To systematically review trials that assessed sensitivity, specificity, l... |
31,471 | Prophylaxis of thrombosis with low-molecular-weight heparin (LMWH). | Deep vein thrombosis (DVT) and pulmonary embolism (PE) are a major cause of morbidity and mortality, affecting approximately 4 million people each year in the United States. The identification of risk factors for the development of DVT and PE helped to develop a system for risk stratification. The risk to develop a dee... |
31,472 | Travel as a risk factor for venous thromboembolic disease. | There is increasing evidence that prolonged travel may be associated with the development of venous thromboembolic disease: ie deep venous thrombosis and pulmonary embolism. The data from case reports, retrospective reviews and case control studies have been confirmed by prospective studies. There have been several pro... |
31,473 | Prevention of venous thromboembolism in pregnancy. | Venous thromboembolic complications (VTE) are a leading causes of maternal mortality in the developed World. To reduce the incidence VTE in pregnancy, and improve outcomes, a wider understanding of the risk factors involved and a better identification of women at risk of thrombosis coupled with effective thromboprophyl... |
31,474 | Thromboprophylaxis in immobilized medical patients. | Venous thromboembolism accounts for a large number of preventable deaths. The majority of these events occur in medical patients, but medical thromboprophylaxis remains underutilised in this population. The purpose of this review is to examine the results of recent clinical trials of low molecular weight heparins in th... |
31,475 | Antithrombotic therapy with low molecular weight heparin in cancer patients. | Thrombosis is a common complication in patients with cancer. Low molecular weight heparins have been shown to be effective in both the prevention and treatment of venous thromboembolism in the cancer patient. More recently, studies have confirmed the benefits of extended duration of LMWH in the primary prevention of VT... |
31,476 | Prevention of deep vein thrombosis in orthopedic surgery. | In the absence of thromboprophylaxis, venous thromboembolism (VTE) affects about 50 to 80% of the patients after total hip replacement (THR), total knee replacement (TKR), or hip fracture surgery. Since stratification of patients in those who will become symptomatic and those who will not, is not possible, primary high... |
31,477 | Epidemiology, etiology and diagnosis of venous thrombosis. | Venous thromboembolism (VTE) is one of the most frequent multifactorial diseases. It manifests clinically by deep vein thrombosis (DVT) and pulmonary embolism (PE) leading to death in about 6%. It is important to emphasize, that 50% of the patients do not present any symptoms. The prevalence is influenced by age and et... |
31,478 | The transjugular intrahepatic portosystemic shunt in the treatment of portal hypertension. | The transjugular intrahepatic portosystemic shunt (TIPS) represents a major advance in the treatment of complications of portal hypertension. It is most commonly used in the management of refractory variceal bleeding, where it can be life-saving. Two other indications have been studied in randomized controlled trials: ... |
31,479 | Free vascularized osteocutaneous fibular graft to the tibia in 51 consecutive cases. | The authors reviewed retrospectively the clinical results of 51 consecutive cases of vascularized osteocutaneous fibular graft to the tibia for the reconstruction of extensive tibial bone and soft-tissue defects. The mean duration of follow-up was 31 months (range: 13 to 76 months). In the 51 procedures of free vascula... |
31,480 | [Low molecular weight heparins: mechanisms of action and pharmococynetics. Clinical advantages over the classic unfractioned heparins]. | Low molecular weight heparins inaugurated a new era in the treatment and prevention of cardiovascular pathology. In this paper, a deep analysis of their mechanisms of action and pharmococynetics is made, and the advantages of its clinical utilization are emphasised, when compared to the classic unfractioned heparins. |
31,481 | [Chronic abdominal pain due to bowel ischemia in a patient with Leiden factor V mutation]. | Leiden Factor V mutation, associated with resistance to activated protein C, is a prothrombotic state found in 20% of the patients with a first episode of deep-vein thrombosis. We report the case of a 30-Year-old woman with a history of intermittent abdominal pain who developed small bowel infarction requiring extensiv... |
31,482 | [Plantar venous thrombosis and anticardiolipin antibody syndrome. Case report]. | We report a case of isolated plantar venous thrombosis in a young female with no recent history of surgery or trauma who complained of spontaneous left talalgia. She was treated with aspirin for a lupus anticoagulant. The diagnosis was established on the basis of color duplex ultrasonography. The patient was given long... |
31,483 | Risk factors and clinical presentation of portal vein thrombosis in patients with liver cirrhosis. | <AbstractText Label="BACKGROUND/AIMS" NlmCategory="OBJECTIVE">Portal vein thrombosis in patients with liver cirrhosis is usually associated to hepatocellular carcinoma. Clinical presentation of non-neoplastic portal vein thrombosis (PVT) in cirrhotic patients has not been specifically studied and risk factors of PVT in... |
31,484 | Possible mechanisms of the cardiovascular effects of inhaled particles: systemic translocation and prothrombotic effects. | Particulate air pollution is associated with cardiovascular morbidity and mortality. Fine particles with a diameter <2.5 microm (PM2.5) have an important role in triggering biological responses. These particles, and particularly the ultrafine fraction (<100 nm) penetrate deeply into the respiratory tract. Recentl... |
31,485 | Early onset of heparin-induced thrombocytopenia with thrombosis after open heart surgery: importance of an early diagnosis and Lepirudin treatment. | Heparin-induced thrombocytopenia with thrombosis (HITT) is a rare complication of cardiac surgery with cardiopulmonary bypass. We report two cases of HITT treated with the direct thrombin inhibitor Lepirudin. Immediate diagnosis was essential to prompt heparin discontinuation and successful early Lepirudin administrati... |
31,486 | Comparison of the effect of fondaparinux and enoxaparin on thrombin generation during in-vitro clotting of whole blood and platelet-rich plasma. | Fondaparinux, a selective antithrombin-dependent inhibitor of activated factor X (FXa), is effective in the prevention and treatment of deep vein thrombosis and seems to be superior to enoxaparin. However, the exact mechanism of fondaparinux antithrombotic action is still unclear. We compared the effect of clinically r... |
31,487 | Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock. | In 2003, critical care and infectious disease experts representing 11 international organizations developed management guidelines for severe sepsis and septic shock that would be of practical use for the bedside clinician, under the auspices of the Surviving Sepsis Campaign, an international effort to increase awarenes... |
31,488 | Safety and outcomes of short-term multiple femoral venous sheath placement in cardiac electrophysiological study and radiofrequency catheter ablation. | Multiple intracardiac catheters are often necessary for electrophysiological study (EPS) and radiofrequency (RF) ablation therapy. Therefore, multiple venous sheath placement in one femoral vein is always required for multiple intracardiac catheter insertion. The vascular complications incurred by placement of multiple... |
31,489 | Physiologic change in flow velocity and direction of dural venous sinuses with respiration: MR venography and flow analysis. | Blood flow of the internal jugular vein and intracranial venous sinuses is affected by respiratory state. The purpose of this study was to clarify the changes in flow velocity and direction and signal intensities of sigmoid sinuses on phase-contrast (PC) MR images obtained with regular breathing and with deep inspirato... |
31,490 | Background morbidity of headache in an adult general population. Results of the Austrian SERMO (Self-Reported Morbidity) study. | To assess period and point prevalence of headache in Austria and the influence of sociodemographic factors and seasonal variations.</AbstractText>Data for the prevalence of headache were drawn from the database of seven representative surveys in the SERMO study (Self-Reported Morbidity Study). The aims of the SERMO stu... |
31,491 | [Not very commonplace throat pain]. | Jugular vein suppurative thrombophlebitis or Lemierre's syndrome is a rare but distinct clinical entity. It should be considered in young, otherwise healthy adults with "pharyngitis" followed by high fever, painful swelling or pain in a latero-cervical area. Rapid and appropriate treatment is important to control this ... |
31,492 | [Prothrombotic factors in stroke]. | Factor V Leiden and prothrombin 20210A polymorphisms are the most common mutations related to deep vein thrombosis, however their relationship with stroke is debated. This paper studies the possible relationship between both entities.</AbstractText>A case-control study was conducted during 27 months to study their asso... |
31,493 | Life-threatening thrombosis complicating the management of hepatic hemorrhage: anticoagulant treatment in a newborn with hemophilia B. | The authors report the case of a neonate presenting with a distended abdomen and shock from factor IX (F.IX) deficiency and intrahepatic bleeding. After resuscitation and treatment with recombinant F.IX through a central venous line, he developed superior vena cava, upper extremity, and intracerebral venous thrombosis ... |
31,494 | Systemic thrombolytic therapy for late-onset portal vein thrombosis after living-donor liver transplantation. | There have been few reports of noninvasive treatment for portal vein thrombosis (PVT) after liver transplantation.</AbstractText>One adult patient and four pediatric patients developed PVT 5, 14, 14, 16, and 43 months after living-donor liver transplantation, respectively. All five of the patients received a 10-day cou... |
31,495 | Extrahepatic portal vein thrombosis in children: etiology and long-term follow-up. | Mortality of extrahepatic portal vein thrombosis depends on underlying causes other than gastrointestinal bleeding. The aim of this study was to evaluate the etiology, treatment, and prognosis of patients with extrahepatic portal vein thrombosis.</AbstractText>The records of 12 patients (age range: 1-9 years) diagnosed... |
31,496 | Identification of three genetic risk factors for venous thrombosis using a multiplex allele-specific PCR assay: comparison of conventional and new alternative methods for the preparation of DNA from clinical samples. | The demand for thrombophilia testing at the molecular level is increasing and with it the need for a simple and rapid and cost-saving procedure for the preparation of genomic DNA from whole blood samples. The aim of this paper is to compare the efficiency of two conventional commercial procedures (Genomic, Eurobio-Labt... |
31,497 | A review of the clinical uses of ximelagatran in thrombosis syndromes. | Ximelagatran, an oral direct thrombin inhibitor, has been investigated for the prevention and treatment of venous thromboembolism as well as for anticoagulation in atrial fibrillation. Unique properties of ximelagatran are that it is a prodrug, it does not require routine laboratory monitoring and it has minimal drug i... |
31,498 | Cerebral infarct and meningitis secondary to Lemierre's syndrome. | The case is reported of a young man with Fusobacterium necrophorum septicemia who developed cavernous sinus thrombosis, meningitis, carotid artery stenosis and stroke. This article presents the only reported case of arterial stroke in Lemierre's syndrome. Clinical presentation, diagnostic difficulty and treatment are d... |
31,499 | Multifocal polypoid endometriosis presenting as huge pelvic masses causing deep vein thrombosis. | We describe a case of multifocal polypoid endometriosis presenting with advanced bulky disease at a variety of pelvic sites. The extent of tumor and clinical features such as vaginal bleeding and pulmonary embolus were suggestive of a malignant process. Histopathology demonstrated glands that were neither crowded nor c... |
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