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31,200 | Management of anticoagulation in patients who require invasive procedures. | When orally anticoagulated patients need to have surgery, the goals of management are to minimize the risks of thromboembolism and of bleeding from the invasive procedure. Some invasive procedures can be performed while patients are fully or partially anticoagulated because bleeding is rare and/or easily controlled. Wh... |
31,201 | Natural history of paroxysmal nocturnal haemoglobinuria using modern diagnostic assays. | Paroxysmal nocturnal haemoglobinuria (PNH) is an uncommon, acquired disorder of blood cells caused by mutation of the phosphatidylinositol glycan class A (PIG-A) gene. The disease often manifests with haemoglobinuria, peripheral blood cytopenias, and venous thrombosis. The natural history of PNH has been documented in ... |
31,202 | Inherited prothrombotic defects in Budd-Chiari syndrome and portal vein thrombosis: a study from North India. | We studied 57 patients with Budd-Chiari syndrome (BCS) and 48 with portal vein thrombosis (PVT) for underlying inherited prothrombotic defects such as protein C, protein S, and antithrombin III deficiencies. Genetic mutations for factor V Leiden, prothrombin gene 20210A, and methyltetrahydrofolate reductase (MTHFR) C67... |
31,203 | Plasma volume and blood viscosity during 4 h sitting in a dry environment: effect of prehydration. | Deep vein thrombosis and pulmonary thromboembolism are potential problems for travelers, including those who fly. We hypothesized that prehydration with an electrolyte-glucose beverage (EGB) would be better than water for maintaining body fluid balance and preventing increased blood viscosity in immobilized men.</Abstr... |
31,204 | [Perioperative failure of hemodialysis shunts: analysis of risk factors]. | Because vascular access dysfunction results in substantial morbidity in patients undergoing chronic hemodialysis, this complication should be avoided. However, we experienced four patients whose hemodialysis shunts failed within 24 hours postoperatively.</AbstractText>We retrospectively analyzed operations performed un... |
31,205 | [Relationships between hemostatic variables and delay of surgical repair of femoral neck fracture in elderly patients]. | This study was conducted to clarify the preoperative risk of thrombosis in elderly patients with femoral neck fracture by determining the relationships between hemostatic variables and time from injury until surgical repair.</AbstractText>Thirty-four patients over 70 years of age with femoral neck fracture were assigne... |
31,206 | Intrahepatic arterioportal shunting and anomalous venous drainage: understanding the CT features in the liver. | The increased use of high-contrast volume, arterial-phase studies of the liver has demonstrated the frequent occurrence of arterioportal shunts within both the cirrhotic and non-cirrhotic liver. This article sets out to explain the underlying microcirculatory mechanisms behind these commonly encountered altered perfusi... |
31,207 | Morbidity in immunosuppressed (SCID/NOD) mice treated with reovirus (dearing 3) as an anti-cancer biotherapeutic. | Specific viral oncolysis of cancer cells has aroused great interest as a potential anti-cancer therapy. Reovirus was proposed as an anti-cancer biotherapeutic several years ago, as it elicits virus-mediated death of human cancer cells both in vitro and in mouse model systems. A common model system for reovirus oncolysi... |
31,208 | Withholding anticoagulation after a negative result on duplex ultrasonography for suspected symptomatic deep venous thrombosis. | Negative results on simplified compression ultrasonography cannot rule out symptomatic deep venous thrombosis (DVT) without further testing, such as repeated ultrasonography several days later. Repeated testing is costly and inconvenient, and patients are sometimes less likely to return for follow-up tests.</AbstractTe... |
31,209 | Characteristic clinical features of hepatocellular carcinoma associated with Budd-Chiari syndrome: evidence of different carcinogenic process from hepatitis B virus-associated hepatocellular carcinoma. | Budd-Chiari syndrome (BCS) is a known risk factor for hepatocellular carcinoma (HCC). Considering the pathophysiological mechanism of BCS, BCS-associated HCC may have a different carcinogenic process to hepatitis B virus (HBV)-associated HCC, resulting in different characteristic clinical features.</AbstractText>The cl... |
31,210 | PC-SPES: a herbal therapy for the treatment of hormone refractory prostate cancer. | In this review the authors consider the commercially available herbal product PC-SPES. This is a combination of eight different herbs marketed for its effects of reducing prostate specific antigen (PSA) levels, improving pain, and enhancing the quality of life of those with hormone refractory prostate cancer. The evide... |
31,211 | Contrast-enhanced US in the assessment of the ilio-caval axis in deep venous thrombosis. | To assess the feasibility and the accuracy of a new technique in the evaluation of deep venous thrombosis (DVT) in the ilio-caval axis.</AbstractText>Thirty-eight patients with suspected DVT were prospectively examined with unenhanced and enhanced colour-Doppler ultrasonography, and ascending contrast venography. Thirt... |
31,212 | Effect of lipoprotein (a) on platelet activation induced by platelet-activating factor: role of apolipoprotein (a) and endogenous PAF-acetylhydrolase. | Lipoprotein (a) [Lp(a)] is considered an atherogenic lipoprotein, which is also implicated in thrombosis. Lp(a) binds to platelets and modulates the effects of various platelet agonists. Platelet activating factor (PAF) is a potent platelet agonist degraded and inactivated by PAF-acetylhydrolase (PAF-AH), which in plas... |
31,213 | Does surgical technique influence outcomes after simultaneous kidney-pancreas transplantation? | Since 1995, many centers have switched from bladder to enteric drainage of the exocrine secretions in simultaneous kidney-pancreas transplantation (SKPT). Enteric exocrine drainage may be performed with either systemic (systemic-enteric [S-E]) or portal (portal-enteric [P-E]) venous delivery of insulin. Controversy exi... |
31,214 | Management of vascular complications after pediatric liver transplantation. | Sixty-five children underwent liver transplantation (LTx) from March 1995 to December 2002. Cirrhosis due to biliary atresia was the main indication, and hepatic artery thrombosis (HAT) the most common vascular complication (n = 5). Other vascular problems were portal vein thrombosis and stenosis. Another patient devel... |
31,215 | Pediatric liver transplantation: fourteen years of experience at the children institute in São Paulo, Brazil. | This study reports the 14-year experience of a single center on 206 liver transplantations from living and cadaveric donors performed in 179 pediatric patients. Biliary atresia (57.2%) and fulminant hepatitis (9.8%) were the most frequent indications. The mean age of the recipients was 3 years, 7 months (9 months to 18... |
31,216 | The predictive characteristics of D-dimer testing in outpatients with suspected venous thromboembolism: a Bayesian approach. | Despite the widespread use of quantitative methods to measure D-dimer, clinical decisions commonly are based only on binary test information (positive/negative). This study aimed to determine the significance of quantitative D-dimer results in the evaluation of venous thromboembolism (VTE) by means of a differentiated ... |
31,217 | Hyperhomocysteinemia, low folate and vitamin B12 concentrations, and methylene tetrahydrofolate reductase mutation in cerebral venous thrombosis. | Elevated plasma levels of homocysteine are associated with an increased risk of deep-vein thrombosis. Through a case-control study, we examined the potential association among homocysteine, folate and vitamin B12 levels, and the common C677-->T mutation in the methylene tetrahydrofolate reductase (MTHFR) gene in pat... |
31,218 | Contribution of susceptibility-weighted imaging to acute stroke assessment. | Susceptibility-weighted (SW) MRI provides insight into the pathophysiology of acute stroke. We report on the use of SW imaging (SWI) sequences in clinical practice and highlight the future applications.</AbstractText>SWI exploits the magnetic susceptibility effects generated by local inhomogeneities of the magnetic fie... |
31,219 | Venous thromboembolism prophylaxis for surgical patients in an Asian hospital. | Venous thromboembolism (VTE) is increasingly recognized as a significant postoperative complication in Asian hospitals. Recommendations have been published for VTE prophylaxis. We conducted a prospective survey of the risk profile and measures used for VTE prophylaxis in elective surgical patients in our hospital.</Abs... |
31,220 | [Budd-Chiari syndrome: updated treatment modalities]. | Budd-Chiari Syndrome (BCS) refers to hepatic venous outflow obstruction, resulting in simultaneous occurrence of hepatic congestion and portal hypertension, leading to a typical clinical triad consisting of right upper quadrant pain, hepatomegaly and ascites. Contrary to Asia and Africa, where BCS is caused primarily b... |
31,221 | Propensity for hemorrhage and thrombosis in chronic myeloproliferative disorders. | Polycythemia vera (PV) and essential thrombocythemia (ET) are two myeloproliferative disorders (MPDs) with frequent thrombotic and hemorrhagic complications. Thrombosis is often the cause of mortality in PV and ET; hemorrhage occurs more commonly in idiopathic myelofibrosis patients, but is rarely fatal. Thromboses may... |
31,222 | Thrombosis and cancer. | Venous thromboembolism is a common problem in cancer patients. It complicates both the surgical management of those with cancer and has been associated with varying risk for the development of clinical thromboembolism in patients receiving chemotherapy. Unfractionated and low-molecular-weight heparin have been validate... |
31,223 | Vena caval filters: a review for intensive care specialists. | Venous thromboembolism (VTE) is a common complication among patients in the intensive care unit. While anticoagulation remains standard therapy, vena caval filters are an important alternative when anticoagulation is contraindicated. To determine the safety and efficacy of vena caval filters in the treatment of VTE, a ... |
31,224 | [Low molecular weight heparin--a safer anticoagulant in thrombosis and cancer].<Pagination><StartPage>1712</StartPage><EndPage>1715</EndPage><MedlinePgn>1712-5</MedlinePgn></Pagination><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Schulman</LastName><ForeName>Sam</ForeName><Initials>S</Initials><AffiliationI... | Intravascular coagulation is considered a major pathogenetic mechanism for nontraumatic osteonecrosis. The aim of our study was to evaluate the association of thrombophilic factor V G1691A mutation (factor V Leiden) and G20210A prothrombin mutation with the disease. Mutation presence was investigated by polymerase chai... |
31,225 | Retinal choroidal collateral circulation after radial optic neurotomy correlated with the lessening of macular edema. | To evaluate patients who had undergone radial optic neurotomy for central retinal vein occlusion for the presence of retinal choroidal collateral circulation and to correlate these collaterals with changes in macular thickness during follow-up. Radial optic neurotomy is designed to release proposed pressure within the ... |
31,226 | Internal limiting membrane peeling for decompression of macular edema in retinal vein occlusion: a report of 14 cases. | Currently, there is no proven treatment for macular edema due to central retinal vein occlusion (CRVO). Moreover, not all cases with macular edema due to branch retinal vein occlusion (BRVO) respond to laser photocoagulation. We postulated that internal limiting membrane (ILM) peeling for decompression of macular edema... |
31,227 | Purpura fulminans due to Streptococcus pneumoniae sepsis following gastric bypass. | An older female underwent bariatric surgery which was followed by a significant weight loss and diarrhea, from which C. difficile was isolated just before her hospitalization. Less than 48 hours after admission, she became febrile, developed deep venous thrombosis of the leg and a pulmonary embolus. Blood cultures grew... |
31,228 | Unfractionated heparin infusion for thromboprophylaxis in highest risk gastric bypass surgery. | Patients undergoing gastric bypass for obesity are at risk for postoperative venous thromboembolic complications. Per our routine, these patients receive unfractionated heparin (UFH) per a previously described, blood volume-based, subcutaneous prophylactic UFH protocol. However, some patients have additional risk facto... |
31,229 | Italian Society of Cardiovascular Echography (SIEC) Consensus Conference on the state of the art of contrast echocardiography. | Part 1: Technical and methodological issues. Contrast echocardiography is based on the use of gas microbubbles. The size, gas composition and shell structure of the microbubbles modify their stability, resistance to pressure and scattering behavior. A proposed classification of contrast agents is based on the modalitie... |
31,230 | [Diagnostic image (190). A man with melaena. Enteral varices due to portal hypertension]. | A 58-year-old man was seen because of anaemia and melaena, due to bleeding from colonic varices resulting from thrombosis of the V. portae hepatis and the V. lienalis. |
31,231 | The evaluation of the peak flow velocity and cross-sectional area of the femoral artery and vein following totally extraperitoneal vs preperitoneal open repair of inguinal hernias. | Both totally extraperitoneal (TEP) and preperitoneal (PPOR) approaches involve the placement of prosthetic material preperitoneally. As the prosthetic material overlies the femoral artery and vein, we aimed to assess its effect on the velocity and the diameter of the artery and vein, using colour Doppler ultrasonograph... |
31,232 | [An update on thrombosis prophylaxis in orthopaedic and accident surgery]. | The prevention of deep venous thrombosis has become a routine in orthopaedic surgery. While the necessity for prophylaxis is not questioned, its practice is still a matter of controversy. The development of new anticoagulants increases the variety of prophylactic methods but leads to a need for additional information. ... |
31,233 | Hepatic allograft salvage with early doppler ultrasound diagnosis of acute vena cava thrombosis. | Postoperative inferior vena cava obstruction is an uncommon complication after liver transplantation. Outflow obstruction, if not rapidly corrected, can lead to graft failure and the patient's death. We report a case in which Doppler ultrasound showed the thrombus inside the vessel, excluding extrahepatic causes of ven... |
31,234 | Successful treatment of acute Budd-Chiari syndrome with percutaneous transluminal angioplasty. | A 26-year-old man developed progressive, massive ascites and hematemesis due to rupture of esophageal varices. Combination diagnostic modalities of color doppler ultrasonography, enhanced computed tomography, and magnetic resonance imaging led to the case being diagnosed as acute Budd-Chiari syndrome with severe strict... |
31,235 | Deep vein thrombosis after elective cesarean section. | Pregnancy is associated with an overall 5-10 fold increased risk of venous thromboembolism (VTE). The absolute risk is highest during and shortly after delivery. Although operative delivery further increases the risk of VTE, there is no consensus on thromboprophylaxis after an elective cesarean. The aim of the present ... |
31,236 | The prothrombotic state in cancer: pathogenic mechanisms. | Thrombosis and disseminated intravascular coagulation (DIC) are common complications in cancer. Patients with malignancy have a prothrombotic state due to the ability of almost all type of cancer cells to activate the coagulation system. However, none of the haemostatic markers of coagulation has any predictive value f... |
31,237 | A survey of orthopedic surgeons regarding DVT prophylaxis in foot and ankle trauma surgery. | This study hypothesized that thromboembolism in patients with foot and ankle trauma is higher than currently recognized, and that prophylaxis varies among surgeons. A questionnaire sent to members of two orthopedic specialty societies surveyed the use of thromboembolic prophylaxis over 1 year. Most did not use preopera... |
31,238 | Adventitial cystic disease of the external iliac vein presenting with deep venous thrombosis. A case report. | Adventitial cystic disease of the venous system is a rare occurrence with only 8 reported cases in the world literature. The most commonly involved segment has been the common femoral vein, resulting in luminal compromise and presenting with extremity swelling. Painless swelling of the right lower extremity in a 37-yea... |
31,239 | Factor V Leiden mutation in pregnancy. | Normal maternal adaptation to pregnancy significantly increases the risk for thrombus formation. Inherited thrombophilias further increase risk for deep venous thrombosis and adverse outcome in pregnancy. Factor V Leiden mutation is the most common inherited thrombophilia, occurring in approximately 5% of the White and... |
31,240 | Effect of plasminogen activator inhibitor-1 4G/5G polymorphism in Turkish deep vein thromboembolic patients with and without prothrombin 20210 G-A. | Prothrombin 20210 G-A mutation is a common factor that predispose to thrombosis. The effect of the mutations in PAI-1 gene on the risk of thrombosis is controversial. We aimed to evaluate the role of these two polymorphisms in Turkish patients with deep vein thrombosis. Although there was no statistically significant d... |
31,241 | Low-molecular-weight heparins in thrombosis and cancer: emerging links. | Heparin as well as low-molecular-weight heparins (LMWHs) have polypharmacological actions at various levels. Earlier studies focused on the plasma anti-Xa and anti-IIa pharmacodynamics (PD) for the different LMWHs. Other important PD parameters for heparin and LMWHs might explain the diverse clinical impacts of this cl... |
31,242 | The dose-response relation between serum homocysteine and cardiovascular disease: implications for treatment and screening. | With the recognition that serum homocysteine may cause cardiovascular disease there is clinical interest in homocysteine measurement to guide treatment with folic acid. It is uncertain whether treatment is best directed at those with high homocysteine or those at high risk irrespective of initial homocysteine.</Abstrac... |
31,243 | Cerebral venous thrombosis. | Cerebral venous thrombosis is an infrequent condition characterized by extreme variability in its clinical presentation and mode of onset. The combination of magnetic resonance imaging and magnetic resonance angiography is currently the best method for diagnosis. The proportion of cases of unknown etiology remains high... |
31,244 | Pharmacomechanical thrombolysis and early stent placement for iliofemoral deep vein thrombosis. | To evaluate an approach to the treatment of iliofemoral deep vein thrombosis (DVT) that included pharmacomechanical catheter-directed thrombolysis with reteplase and the Helix mechanical thrombectomy device, followed by early stent placement.</AbstractText>During 3-year period, 23 symptomatic limbs in 18 patients with ... |
31,245 | Cost-effectiveness of testing for hypercoagulability and effects on treatment strategies in patients with deep vein thrombosis. | Among patients with deep vein thrombosis, hypercoagulable conditions impart a substantial risk of recurrent thrombosis. We sought to determine the cost-effectiveness of testing for these disorders, as well as which tests should be selected and how results should be used.</AbstractText>Using a Markov state-transition mo... |
31,246 | Stroke in women of reproductive age: comparison between stroke related and unrelated to pregnancy. | Pregnancy may increase the risk of stroke. However, few studies have compared strokes in women of reproductive age that occur in pregnancy or the puerperium (pregnancy-related stroke, PRS) with those unrelated to pregnancy. This study assesses risk factors and etiologies of stroke in these women based on relationship t... |
31,247 | Retinal vein occlusions in patients taking warfarin. | To describe development of retinal vein occlusion (RVO) in patients anticoagulated with warfarin.</AbstractText>Retrospective, observational case series.</AbstractText>Thirteen patients drawn from a private retina practice.</AbstractText>Review of clinical records, laboratory results, color fundus photographs, and fluo... |
31,248 | Non-traumatic lower limb vascular complications in endurance athletes. Review of literature. | To review the importance, clinical features, investigations, management and prognosis of non-traumatic vascular injuries, affecting the lower limbs of endurance athletes.</AbstractText>Review of literature.</AbstractText>A literature search was conducted from Medline, Pubmed, the National Electronic Library for Health,... |
31,249 | Antiphospholipid antibodies in primary Sjögren's syndrome: prevalence and clinical significance in a series of 74 patients. | The aim of this study is to determine prevalence, clinical significance of antiphospholipid antibodies (aPL) including anticardiolipin antibodies (aCL), anti-beta2GP1 and lupus anticoagulant (LA) in a cohort of 74 patients with primary Sjögren's syndrome (pSS) according to revised European criteria. aPL were found... |
31,250 | Efficacy of multi-slice helical CT venography for the diagnosis of deep venous thrombosis: comparison with venous sonography. | The purpose of this study was to assess the efficacy of contrast enhanced multi-slice helical CT (MSCT) venography for the diagnosis of deep venous thrombosis (DVT) in comparison with venous sonography.</AbstractText>MSCT was used to obtain contiguous, 5-mm thick axial CT images from the diaphragm to the ankles of 27 p... |
31,251 | Rapid D-dimer test combined a clinical model for deep vein thrombosis. Validation with ultrasonography and clinical follow-up in 383 patients. | An optimal approach to the diagnosis of deep vein thrombosis (DVT) in lower limbs in the emergency department is still unknown. In this prospective cohort study, we aimed to evaluate the accuracy of the widely available plasma D-dimer test (VIDAS) and establish the usefulness of combining D-dimer testing with a clinica... |
31,252 | In proven deep vein thrombosis, a low positive D-Dimer score is a strong negative predictor for associated malignancy. | D-Dimer measurements are being increasingly used for negative prediction of deep vein thrombosis (DVT). At our institution, clinical score, D-Dimer assay, plethysmography and, if necessary, Doppler ultrasound are used to secure the diagnosis. We collected the data from 100 consecutive patients proven to have DVT. We ex... |
31,253 | The Ser460Pro mutation in recombinant protein S Heerlen does not affect its APC-cofactor and APC-independent anticoagulant activities. | Protein S is a vitamin K-dependent plasma protein that functions as an APC-cofactor, but also exhibits anticoagulant activity in the absence of APC. The Heerlen polymorphism of protein S is characterized by a Ser460Pro substitution and lacks glycosylation at Asn458. It is associated with decreased protein S levels due ... |
31,254 | Effect of recombinant factor VIIa on melagatran-induced inhibition of thrombin generation and platelet activation in healthy volunteers. | The objectives were to investigate whether activation of the extrinsic coagulation cascade by recombinant factor VIIa (rFVIIa) reverses the inhibition of thrombin generation and platelet activation by melagatran, the active form of the oral direct thrombin inhibitor ximelagatran. In a single-blind, randomized, parallel... |
31,255 | Therapeutic effect of diagnostic ultrasound on enzymatic thrombolysis. An in vitro study on blood of normal subjects and patients with coronary artery disease. | If delivered at elevated intensity, ultrasound potentiates enzymatic clot dissolution; however, an elevated acoustic intensity damages vascular wall and favors reocclusion. This study's aim was to investigate whether exposure to high-frequency, low-intensity ultrasound - generated by a diagnostic scanner -enhances enzy... |
31,256 | A case of right loin pain: septic ovarian vein thrombosis due to Campylobacter fetus bacteraemia. | Septic ovarian venous thrombosis is an uncommon condition. Diagnosis is often not immediately apparent clinically and there are many that mimic this condition. We described an unusual case of septic ovarian vein thrombosis associated with Campylobacter fetus (C. fetus) bacteraemia.</AbstractText>A 46-year-old female pr... |
31,257 | The use of in-line intravenous filters in sick newborn infants. | This study assesses the improvement in outcome for newborn infants by decreasing major complications associated with intravenous fluid therapy by using an in-line filter, and evaluates the economical impact this might have in relation to daily changing of i.v. lines.</AbstractText>In a prospective controlled study, 88 ... |
31,258 | [Cerebral venous thrombosis--clinical aspects and consequences]. | The clinical picture of cerebral venous thrombosis (CVT) depends on the site of thrombosis in the venous system including superficial veins, deep veins and venous sinuses. Thrombotic changes may occur simultaneously in various parts of the venous system. Since CVT may have various causes, the knowledge of its etiology ... |
31,259 | Closed suction drainage for hip and knee arthroplasty. A meta-analysis. | The use of closed-suction drainage systems after total joint replacement is a common practice. The theoretical advantages for the use of drains is a reduction in the occurrence of wound hematomas and infection. The aim of this meta-analysis was to determine, on the basis of the evidence from randomized controlled trial... |
31,260 | Fondaparinux or enoxaparin for the initial treatment of symptomatic deep venous thrombosis: a randomized trial. | The current standard initial therapies for deep venous thrombosis are low-molecular-weight heparin and unfractionated heparin. In a dose-ranging study of patients with symptomatic deep venous thrombosis, fondaparinux had efficacy and a safety profile similar to those of low-molecular-weight heparin (dalteparin).</Abstr... |
31,261 | Natural anticoagulant inhibitors: activated Protein C. | Protein C is a vitamin-K-dependent zymogen, whose congenital deficiency state leads to increased risk for venous thrombosis. Activated Protein C (aPC) exerts its anticoagulant function by inhibiting the cofactors in the clotting cascade, Factors Va and VIIIa. In addition, aPC displays anti-inflammatory, anti-apoptotic ... |
31,262 | Oral delivery of heparin: SNAC and related formulations. | Unfractionated heparin is one of the most commonly used pharmacological agents in hospital practice. The use of this agent is inconvenient in that it must be given parenterally. Current research is directed at development of oral antithrombotic agents that will not require laboratory monitoring of the antithrombotic ef... |
31,263 | Ximelagatran: a new oral anticoagulant. | Vitamin K antagonists are effective oral anticoagulants, but they have limitations related to a narrow therapeutic range, food and drug interactions, slow onset of action and the need for routine coagulation monitoring. Ximelagatran is a promising new oral anticoagulant under investigation in advanced clinical trials. ... |
31,264 | Fondaparinux: a new synthetic and selective inhibitor of Factor Xa. | Fondaparinux (Arixtra) is the first synthetic selective Factor Xa inhibitor. Its efficacy and safety in the prevention of venous thromboembolism (VTE) was first studied in patients undergoing major orthopedic surgery, a setting in the highest risk category for postoperative thrombotic complications. Low-molecular-weigh... |
31,265 | Low- and ultra-low-molecular-weight heparins. | Heparins and low-molecular-weight heparins (LMWHs) have been the mainstay for the prevention and management of venous and arterial thromboembolic disease. In particular, the LMWHs have become well established in the past 15 years for the prevention of thrombosis in medium- and high-risk surgical and medical patients an... |
31,266 | Hyperhomocysteinemia and other thrombophilic risk factors in 26 patients with cerebral venous thrombosis. | Despite the continuous description of new conditions pre-disposing for cerebral venous thrombosis (CVT), no apparent cause is found in about 30% of cases. Hyperhomocysteinemia (hyper-Hcy) is an established risk factor for deep venous thrombosis and stroke but has not been clearly associated with increased risk of CVT. ... |
31,267 | Sonorheometry: a noncontact method for the dynamic assessment of thrombosis. | Inappropriate blood coagulation plays a central role in the onset of myocardial infarction, stroke, pulmonary embolism, and other thrombotic disorders. The ability to screen for an increased propensity to clot could prevent the onset of such events by appropriately identifying those at risk and enabling prophylactic tr... |
31,268 | Percutaneous closure of atrial septal defect via transjugular approach with the Amplatzer septal occluder after unsuccessful attempt using the CardioSEAL device. | Percutaneous closure of a secundum atrial septal defect was performed successfully via the jugular approach in a 77-year-old patient with heparin-induced thrombocytopenia and total occlusion of the inferior vena cava using the Amplatzer septal occluder after an unsuccessful attempt using the CardioSEAL septal occluder.... |
31,269 | [Repeated thromboembolism during pregnancy with constitutional antithrombin deficiency]. | We report the case of a twenty-three-year old woman with constitutional antithrombin deficiency, who had oral anticoagulation since she was four years old. During her first pregnancy, after the introduction of unfractionated heparin prophylactic therapy, she presented a first venous thromboembolism at nine weeks, and a... |
31,270 | Fibrinogen polymorphisms TaqI, HaeIII and BclI are not associated with a higher risk of deep vein thrombosis. | High fibrinogen is recognised as a risk factor for atherosclerosis. It seems that high fibrinogen is also a risk factor for deep vein thrombosis (DVT). It has been shown that certain polymorphisms in fibrinogen genes can influence the fibrinogen level. In this study, fibrinogen levels and the frequency of the polymorph... |
31,271 | Factor V gene (1691A and 4070G) and prothrombin gene 20210A mutations in patients with Behçet's disease. | Behçet's disease (BD) is a chronic inflammatory disorder of still unknown etiology, characterized by endothelial cell injury/dysfunction and thrombosis and/or aneurysm of large blood vessels. Thrombophilia may play a role in the pathogenesis of thrombosis in BD. The common inherited gene defects, factor V (FV) 169... |
31,272 | The effect of dietary bacillus natto productive protein on in vivo endogenous thrombolysis. | The influence of dietary bacillus natto productive protein (BNPP) on endogenous thrombolysis was investigated in the rat. Animals were given a standard feed for 14 weeks, to which 0.2 or 1% BNPP was added. Thrombolysis was evaluated using an He-Ne laser-induced thrombosis model in mesenteric microvessels. Changes in th... |
31,273 | Medical complications in hemodialysis patients requiring vascular access radiology procedures. | Vascular access maintenance is crucial to providing adequate hemodialysis (HD) and hence preventing signs and symptoms of uremia. The best vascular assess is a permanent arteriovenous fistula (AVF) because it has the longest survival with the least number of complications. However, because of problems with AVF maturati... |
31,274 | [Pulmonary thromboembolism complicating right subclavian vein obstruction: case report]. | We report a case of pulmonary thromboembolism, in which obstruction of the right subclavian vein, also called Paget-von Schroetter syndrome, was detected. The patient was a 39-year-old man (a scaffold constructor). He lost consciousness at work, and was admitted as an emergency case to our hospital. He had noticed grad... |
31,275 | Recurrent life-threatening thromboembolism and catastrophic antiphospholipid syndrome in a patient despite sufficient oral anticoagulation. | We report on a 32-year old female patient with primary antiphospholipid syndrome (PAPS) and several thromboembolic events despite stable doses of oral anticoagulation, good patient compliance and maintained INR values of >3. Over the preceding 3 years the patient had presented a wide spectrum of manifestations of AP... |
31,276 | Behçet's syndrome and the nervous system. | Behçet's syndrome (BS) is a multi-system, vascular-inflammatory disease of unknown origin, involving the nervous system in a subgroup of patients. The syndrome is rare, but as patients with BS are young and frequently present with an acute or subacute brainstem syndrome or hemiparesis, as well as with other variou... |
31,277 | The natural history of pancreatitis-induced splenic vein thrombosis. | To determine the natural history of pancreatitis-induced splenic vein thrombosis with particular attention to the risk of gastric variceal hemorrhage.</AbstractText>Previous studies have suggested that splenic vein thrombosis results in a high likelihood of gastric variceal bleeding and that splenectomy should be perfo... |
31,278 | Successful treatment of post-exertion acute myocardial infarction by primary angioplasty and stenting in a patient with antiphospholipid antibody syndrome. | Antiphospholipid syndrome is a disorder characterized by arterial and venous thromboses, thrombocytopaenia and stroke. Acute myocardial infarction is rarely associated with this syndrome. The treatment of these patients is a clinical challenge. This report is about a patient with antiphospholipid syndrome presenting wi... |
31,279 | Venous and arterial thrombosis in rat models: dissociation of the antithrombotic effects of glycosaminoglycans. | Fucosylated chondroitin sulfate is a glycosaminoglycan from sea cucumber, made up of alternating beta-D-glucuronic acid and N-acetyl-beta-D-galactosamine units, like mammalian chondroitin sulfate. But the beta-D-glucuronic acid residues have branches of sulfated fucose, which confer high anticoagulant and antithromboti... |
31,280 | Clinical and laboratory evaluation of Turkish children with thrombosis for homozygous factor V G1691A mutation. | Factor V (FV) G1691A mutation, in a heterozygous state, is one of the most common inherited risk factors for development of thrombosis. However, the clinical manifestations of homozygosity for the FV G1691A mutation in children is largely unknown because of the limited number of studies reported. The purpose of this st... |
31,281 | Magnetic resonance venography in consecutive patients with suspected deep vein thrombosis of the upper extremity: initial experience. | To assess the feasibility and accuracy of two magnetic resonance (MR) venography methods in a consecutive series of patients with suspected deep vein thrombosis of the upper extremity (DVTUE).</AbstractText>Consecutive in- and outpatients who were referred for imaging of suspected DVTUE in a large teaching hospital dur... |
31,282 | Mesenteric and portal vein thrombosis presenting as acute intestinal obstruction. | Acute bowel infarction is a major complication in patients with superior mesenteric vein and portal vein thrombosis. However, in some patients, sufficient collaterals can prevent acute bowel infraction. We present a case of mesenteric vein and portal vein thrombosis with intestinal obstruction due to acute bowel oedema... |
31,283 | Role of surgical portosystemic shunts in the era of interventional radiology and liver transplantation. | In the present era of liver transplantation and transjugular intrahepatic portosystemic shunts, the role and choice of shunt surgery for portal hypertension was reviewed.</AbstractText>This retrospective study analysed the management of patients with portal hypertension in a tertiary liver transplant unit between June ... |
31,284 | Warfarin-induced limb gangrene in the setting of lung adenocarcinoma. | A 53-year-old man with lung adenocarcinoma developed pulmonary embolism and bilateral popliteal venous thrombosis. Treated with intravenous unfractionated heparin and discharged home on warfarin, he returned a week later with extending thrombosis. Treatment with heparin followed by warfarin was reinitiated. Twenty-four... |
31,285 | Molecular basis of inherited antithrombin deficiency in Portuguese families: identification of genetic alterations and screening for additional thrombotic risk factors. | Antithrombin (AT), the most important coagulation serine proteases inhibitor, plays an important role in maintaining the hemostatic balance. Inherited AT deficiency, mainly characterized by predisposition to recurrent venous thromboembolism, is transmitted in an autosomal dominant manner. In this study, we analyzed the... |
31,286 | Thromboembolic complications after splenectomy for hematologic diseases. | Thromboembolic complications following splenectomy for hematologic diseases occur in up to 10% of patients and may range from portal vein thrombosis (PVT) to pulmonary embolism (PE) and deep vein thrombosis (DVT). Up to now there exist no recommendations for the duration and intensity of prophylactic anticoagulation, w... |
31,287 | Acute appendicitis-like symptoms as initial presentation of ovarian vein thrombosis. | Postpartum ovarian vein thrombosis is a rare condition, with an incidence rate being 1/600 deliveries. It most often arises in the right ovarian vein. A 33-year-old patient who had had normal vaginal delivery presented with fever, pain in the right iliac fossa, and leukocytosis on the sixth day after delivery. An antib... |
31,288 | Evaluation of the efficacy of heparins of varying molecular mass and duration of their use in the treatment of patients with acute venous thrombosis. | This paper analyses the results of examination and treatment of 90 patients with acute thrombosis in the inferior vena cava system. To verify the diagnosis, use was made of contrast phlebography (retrograde iliocavography), ultrasound angioscanning, and perfusion scanning of the lungs, The treatment was carried out usi... |
31,289 | [Aspirin versus oral anticoagulants following lower limb arterial reconstructions: what to choose?]. | Graft thrombosis in long-term postoperative period after lower extremity arterial reconstructions often results in limb loss. In some studies prolonged antithrombotic therapy was demonstrated to improve long-term patency of vascular grafts. Nevertheless little consensus exists on the optimal antithrombotic agents. The ... |
31,290 | [Real embologenicity of thromboses of lower extremity veins]. | The aim of the present work was to study real embologenicity of thromboses of lower extremity veins. We carried out a comparative evaluation of the embologenic risk of different thromboses of the superficial and deep veins associated with hospital treatment. The study performed allows the following conclusions to be dr... |
31,291 | The importance of D-dimer for the diagnosis of venous thromboses in clinical cardiology. | The aim of the study was to analyze the importance of the rapid assay for D-dimer in the diagnosis of venous thromboses (VT). The study accrued 82 patients. There were 57 (70%) men and 25 (30%) women aged 16 to 86 years. Fifty-three patients were suspected of deep venous thrombosis (DVT) and 29 of pulmonary thromboembo... |
31,292 | The therapeutic potential of ximelagatran to become the anticoagulant of choice in medicine: a review of recently completed clinical trials. | Ximelagatran (Exanta, AstraZeneca) is a novel oral direct thrombin inhibitor that inhibits the final step in the coagulation process - namely, the conversion of fibrinogen to insoluble fibrin by thrombin. Recently completed large clinical trials have evaluated the efficacy and safety of ximelagatran compared to standar... |
31,293 | Fondaparinux: a Factor Xa inhibitor for antithrombotic therapy. | Fondaparinux (Arixtra) is the first of a new class of antithrombotic compounds - Factor Xa inhibitors. This synthetic pentasaccharide acts by inhibiting Factor Xa selectively. Its efficacy and safety have been demonstrated in animal models of venous and arterial thromboses and bleeding risk. In humans, its pharmacokine... |
31,294 | Dural sinus thrombosis after cardiopulmonary bypass. | Cerebral venous thrombosis in various clinical conditions, such as congenital heart disease (CHD) and hypercoagulable states, have been recognized previously. However, dural sinus thrombosis in a pediatric patient with Antiphospholipid Syndrome (APLS) after the repair of a ventricular septal defect (VSD) has not been r... |
31,295 | The surgical management of thoracolumbar injuries. | This review addresses the epidemiology, clinical examination, and radiographic evaluation and fracture classification of thoracolumbar injuries. The factors that indicate surgical intervention and the surgical management of specific injuries such as compression fractures, burst fractures, flexion-distraction, and fract... |
31,296 | Umbilical portion of recipient's left portal vein: a useful vascular conduit in dual living donor liver transplantation for the thrombosed portal vein. | We considered performing living donor liver transplantation (LDLT) in a larger-size recipient. When the recipient was large-sized, or when the donor liver was severely steatotic or had a right-to-left volume discrepancy. We devised dual living donor liver transplantation (DLDLT) to make up for graft size insufficiency ... |
31,297 | Increased endothelin-1 plasma level in young adults with retinal vascular occlusive diseases. | Vascular occlusive diseases are usually seen in the elderly but can occur even in younger patients without arteriosclerosis. We assume a vascular dysregulation as a underlying pathogenetic mechanism.</AbstractText>In a prospective study we analysed the clinical findings of six patients under 55 years of age, three men ... |
31,298 | CT of small bowel ischemia. | We evaluated the computed tomographic (CT) features of small bowel (SB) ischemia and necrosis and correlated the findings with clinical outcome or patient prognosis. Sixty-eight surgically or angiographically proved cases of SB ischemia were retrospectively reviewed. The CT features of intestinal ischemia were divided ... |
31,299 | [Diagnostic image (188). A man suffering from a swollen and red arm. Deep venous thrombosis of the arm]. | A 25-year-old man presented with a deep venous thrombosis of the left arm due to excessive lifting of household materials (Paget-Schroetter syndrome). |
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