CUI1 stringlengths 8 8 | RELA stringlengths 3 54 | CUI2 stringlengths 8 8 | Name1 stringlengths 1 2.86k ⌀ | Name2 stringlengths 1 2.86k ⌀ | Def1 stringlengths 1 8.95k ⌀ | Def2 stringlengths 1 8.95k ⌀ |
|---|---|---|---|---|---|---|
C0000530 | mapped_to | C1439160 | 5'-NUCLEOTIDASE | NT5C3A protein, human | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | Cytosolic 5'-nucleotidase 3A (336 aa, ~38 kDa) is encoded by the human NT5C3A gene. This protein is involved in the dephosphorylation of pyrimidine 5' monophosphates. |
C0000530 | mapped_to | C1506068 | 5'-NUCLEOTIDASE | SDT1 protein, S cerevisiae | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | mapped_to | C1610831 | 5'-NUCLEOTIDASE | Nt5c3 protein, mouse | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | mapped_to | C1701467 | 5'-NUCLEOTIDASE | NT5C2 protein, human | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | Cytosolic purine 5'-nucleotidase (561 aa, ~65 kDa) is encoded by the human NT5C2 gene. This protein plays a role in the maintenance of intracellular purine pools. |
C0000530 | mapped_to | C1849507 | 5'-NUCLEOTIDASE | Uridine 5-Prime Monophosphate Hydrolase Deficiency, Hemolytic Anemia due to | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | Hemolytic anemia due to pyrimidine 5' nucleotidase deficiency is a rare, hereditary, hemolytic anemia due to an erythrocyte nucleotide metabolism disorder characterized by mild to moderate hemolytic anemia associated with basophilic stippling and the accumulation of high concentrations of pyrimidine nucleotides within ... |
C0000530 | mapped_to | C2930876 | 5'-NUCLEOTIDASE | 5-Nucleotidase syndrome | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | mapped_to | C2932861 | 5'-NUCLEOTIDASE | NT5E protein, human | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | 5'-nucleotidase (574 aa, ~63 kDa) is encoded by the human NT5E gene. This protein is involved in the conversion of nucleotides to nucleosides. |
C0000530 | mapped_to | C2932862 | 5'-NUCLEOTIDASE | Nt5e protein, mouse | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | mapped_to | C2932863 | 5'-NUCLEOTIDASE | Nt5e protein, rat | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | mapped_to | C2973299 | 5'-NUCLEOTIDASE | NT5C1B protein, human | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | mapped_to | C2973302 | 5'-NUCLEOTIDASE | NT5C1A protein, human | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | Cytosolic 5'-nucleotidase 1A (368 aa, ~41 kDa) is encoded by the human NT5C1A gene. This protein plays a role in the hydrolysis of ribonucleoside and deoxyribonucleoside monophosphates. |
C0000530 | mapped_to | C2973303 | 5'-NUCLEOTIDASE | NT5M protein, human | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | mapped_to | C3529147 | 5'-NUCLEOTIDASE | Nt5e protein, Streptococcus sanguinis | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | mapped_to | C4548361 | 5'-NUCLEOTIDASE | NT5C1A protein, mouse | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | mapped_to | C4548362 | 5'-NUCLEOTIDASE | NT5C2 protein, mouse | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | mapped_to | C5391973 | 5'-NUCLEOTIDASE | Nt5dc2 protein, rat | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | mapped_to | C5543955 | 5'-NUCLEOTIDASE | NT5DC2 protein, human | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | associated_with | C0523870 | 5'-NUCLEOTIDASE | Pyrimidine-5'-nucleotidase measurement | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | measures | C0363823 | 5'-NUCLEOTIDASE | 5'-Nucleotidase:CCnc:Pt:Amnio fld:Qn | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | measures | C0363824 | 5'-NUCLEOTIDASE | 5'-Nucleotidase:CCnc:Pt:Ser/Plas:Qn | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | measures | C0365046 | 5'-NUCLEOTIDASE | Pyrimidine-5'-Nucleotidase:PrThr:Pt:Bld:Ord | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | measures | C0365047 | 5'-NUCLEOTIDASE | Pyrimidine-5'-Nucleotidase:CCnc:Pt:Bld:Qn | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | measures | C1715333 | 5'-NUCLEOTIDASE | Pyrimidine-5'-Nucleotidase:CCnt:Pt:Bld:Qn | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | measures | C0367649 | 5'-NUCLEOTIDASE | Deprecated CD73 cells/100 cells in Blood | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | inverse_isa | C1335532 | 5'-NUCLEOTIDASE | Protein Family | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | Collection of proteins that are evolutionarily related. This is reflected in the structural and functional similarities as well as in the extent of sequence conservation or residue identity. (from SCOP) |
C0000530 | is_biochemical_function_of_gene_product | C0014894 | 5'-NUCLEOTIDASE | Esterases | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | Any member of the class of enzymes that catalyze the cleavage of an ester bond and result in the addition of water to the resulting molecules. |
C0000530 | gene_product_has_chemical_classification | C1439160 | 5'-NUCLEOTIDASE | NT5C3A protein, human | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | Cytosolic 5'-nucleotidase 3A (336 aa, ~38 kDa) is encoded by the human NT5C3A gene. This protein is involved in the dephosphorylation of pyrimidine 5' monophosphates. |
C0000530 | gene_product_has_chemical_classification | C1701467 | 5'-NUCLEOTIDASE | NT5C2 protein, human | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | Cytosolic purine 5'-nucleotidase (561 aa, ~65 kDa) is encoded by the human NT5C2 gene. This protein plays a role in the maintenance of intracellular purine pools. |
C0000530 | gene_product_has_chemical_classification | C1740167 | 5'-NUCLEOTIDASE | ACPP protein, human | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | Prostatic acid phosphatase (386 aa, ~45 kDa) is encoded by the human ACP3 gene. This protein is involved in the dephosphorylation of both lipids and tyrosine and has ecto-5'-nucleotidase activity. |
C0000530 | gene_product_has_chemical_classification | C2932861 | 5'-NUCLEOTIDASE | NT5E protein, human | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | 5'-nucleotidase (574 aa, ~63 kDa) is encoded by the human NT5E gene. This protein is involved in the conversion of nucleotides to nucleosides. |
C0000530 | gene_product_has_chemical_classification | C2973302 | 5'-NUCLEOTIDASE | NT5C1A protein, human | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | Cytosolic 5'-nucleotidase 1A (368 aa, ~41 kDa) is encoded by the human NT5C1A gene. This protein plays a role in the hydrolysis of ribonucleoside and deoxyribonucleoside monophosphates. |
C0000530 | inverse_isa | C0014442 | 5'-NUCLEOTIDASE | Enzymes | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | Biological molecules that possess catalytic activity. They may occur naturally or be synthetically created. Enzymes are usually proteins, however CATALYTIC RNA and CATALYTIC DNA molecules have also been identified. |
C0000530 | measures | C1255313 | 5'-NUCLEOTIDASE | Intravascular 5' Nucleotidase Test | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | inverse_isa | C0020289 | 5'-NUCLEOTIDASE | Hydrolase | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | Any member of the class of enzymes that catalyze the cleavage of the substrate and the addition of water to the resulting molecules, e.g., ESTERASES, glycosidases (GLYCOSIDE HYDROLASES), lipases, NUCLEOTIDASES, peptidases (PEPTIDE HYDROLASES), and phosphatases (PHOSPHORIC MONOESTER HYDROLASES). EC 3. |
C0000530 | inverse_isa | C0033684 | 5'-NUCLEOTIDASE | Proteins | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein. |
C0000530 | has_component | C0202148 | 5'-NUCLEOTIDASE | 5' Nucleotidase measurement | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | The determination of the amount of ecto-5'-nucleotidase in a sample. |
C0000530 | has_measured_component | C0202148 | 5'-NUCLEOTIDASE | 5' Nucleotidase measurement | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | The determination of the amount of ecto-5'-nucleotidase in a sample. |
C0000530 | has_component | C0202148 | 5'-NUCLEOTIDASE | 5' Nucleotidase measurement | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | The determination of the amount of ecto-5'-nucleotidase in a sample. |
C0000530 | has_component | C0428313 | 5'-NUCLEOTIDASE | Serum 5-nucleotidase measurement | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | has_measured_component | C0428313 | 5'-NUCLEOTIDASE | Serum 5-nucleotidase measurement | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | disposition_of | C4521917 | 5'-NUCLEOTIDASE | Hydrolase (disposition) | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | inverse_isa | C0443962 | 5'-NUCLEOTIDASE | Cluster of differentiation antigen 56-78 | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | has_component | C3161515 | 5'-NUCLEOTIDASE | tissue enzyme assays fibroblast cd73 activity | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | inverse_isa | C0018928 | 5'-NUCLEOTIDASE | Hematinics | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | Agents which improve the quality of the blood, increasing the hemoglobin level and the number of erythrocytes. They are used in the treatment of anemias. |
C0000530 | inverse_isa | C0443773 | 5'-NUCLEOTIDASE | Red cell enzyme | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | inverse_isa | C0522105 | 5'-NUCLEOTIDASE | Clinically relevant enzymes with no Enzyme Commission designation | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | inverse_isa | C0581802 | 5'-NUCLEOTIDASE | Purine and pyrimidine disorder marker enzyme | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | has_component | C0523870 | 5'-NUCLEOTIDASE | Pyrimidine-5'-nucleotidase measurement | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | has_measured_component | C0523870 | 5'-NUCLEOTIDASE | Pyrimidine-5'-nucleotidase measurement | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | disposition_of | C4521904 | 5'-NUCLEOTIDASE | Red blood cell enzyme (disposition) | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | has_component | C0365046 | 5'-NUCLEOTIDASE | Pyrimidine-5'-Nucleotidase:PrThr:Pt:Bld:Ord | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | has_component | C0365047 | 5'-NUCLEOTIDASE | Pyrimidine-5'-Nucleotidase:CCnc:Pt:Bld:Qn | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | has_component | C1715333 | 5'-NUCLEOTIDASE | Pyrimidine-5'-Nucleotidase:CCnt:Pt:Bld:Qn | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | has_component | C0367649 | 5'-NUCLEOTIDASE | Deprecated CD73 cells/100 cells in Blood | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | has_component | C0363823 | 5'-NUCLEOTIDASE | 5'-Nucleotidase:CCnc:Pt:Amnio fld:Qn | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | has_component | C0363824 | 5'-NUCLEOTIDASE | 5'-Nucleotidase:CCnc:Pt:Ser/Plas:Qn | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | has_component | C5212676 | 5'-NUCLEOTIDASE | Cytosolic 5'-nucleotidase 1A Ab.IgG:PrThr:Pt:Ser/Plas:Ord:IA | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | has_component | C5425616 | 5'-NUCLEOTIDASE | Cytosolic 5'-nucleotidase 1A Ab:ACnc:Pt:Ser:Qn:IA | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000530 | exhibited_by | C1149918 | 5'-NUCLEOTIDASE | 5'-nucleotidase activity | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. [EC:3.1.3.5] |
C0000530 | exhibited_by | C2263478 | 5'-NUCLEOTIDASE | adenosine monophosphatase activity | A glycoprotein enzyme present in various organs and in many cells. The enzyme catalyzes the hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of water. It is cation-dependent and exists in a membrane-bound and soluble form. EC 3.1.3.5. | null |
C0000543 | inverse_isa | C0242701 | 5,6-Dihydroxytryptamine | Serotonin Agents | Tryptamine substituted with two hydroxyl groups in positions 5 and 6. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacologic research. | Drugs used for their effects on serotonergic systems. Among these are drugs that affect serotonin receptors, the life cycle of serotonin, and the survival of serotonergic neurons. |
C0000543 | mapped_to | C0625203 | 5,6-Dihydroxytryptamine | 4,7-dimethyl-5,6-dihydroxytryptamine | Tryptamine substituted with two hydroxyl groups in positions 5 and 6. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacologic research. | null |
C0000543 | mapped_to | C0625205 | 5,6-Dihydroxytryptamine | 4-methyl-5,6-dihydroxytryptamine | Tryptamine substituted with two hydroxyl groups in positions 5 and 6. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacologic research. | null |
C0000543 | mapped_to | C0625207 | 5,6-Dihydroxytryptamine | 7-methyl-5,6-dihydroxytryptamine | Tryptamine substituted with two hydroxyl groups in positions 5 and 6. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacologic research. | null |
C0000543 | mapped_to | C0642132 | 5,6-Dihydroxytryptamine | 5,6-dihydroxy-4-fluorotryptamine creatinine | Tryptamine substituted with two hydroxyl groups in positions 5 and 6. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacologic research. | null |
C0000543 | mapped_to | C0642134 | 5,6-Dihydroxytryptamine | 5,6-dihydroxy-7-fluorotryptamine creatinine | Tryptamine substituted with two hydroxyl groups in positions 5 and 6. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacologic research. | null |
C0000543 | mapped_to | C0642136 | 5,6-Dihydroxytryptamine | 4,7-difluoro-5,6-dihydroxytryptamine creatinine | Tryptamine substituted with two hydroxyl groups in positions 5 and 6. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacologic research. | null |
C0000543 | mapped_to | C0655900 | 5,6-Dihydroxytryptamine | 5,7-dihydroxytryptamine creatinine | Tryptamine substituted with two hydroxyl groups in positions 5 and 6. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacologic research. | null |
C0000544 | inverse_isa | C0242701 | 5,7-Dihydroxytryptamine | Serotonin Agents | Tryptamine substituted with two hydroxyl groups in positions 5 and 7. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacology as a tool. | Drugs used for their effects on serotonergic systems. Among these are drugs that affect serotonin receptors, the life cycle of serotonin, and the survival of serotonergic neurons. |
C0000544 | mapped_to | C0656856 | 5,7-Dihydroxytryptamine | 5-hydroxytryptamine-4,7-dione | Tryptamine substituted with two hydroxyl groups in positions 5 and 7. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacology as a tool. | null |
C0000544 | mapped_to | C0656858 | 5,7-Dihydroxytryptamine | 6,6'-bis(5-hydroxytryptamine-4,7-dione) | Tryptamine substituted with two hydroxyl groups in positions 5 and 7. It is a neurotoxic serotonin analog that destroys serotonergic neurons preferentially and is used in neuropharmacology as a tool. | null |
C0000545 | inverse_isa | C0015689 | eicosapentaenoic acid | omega-3 fatty acids | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | A group of unsaturated fatty acids occurring mainly in fish oils, with three double bonds at particular positions in the hydrocarbon chain. |
C0000545 | inverse_isa | C0542549 | eicosapentaenoic acid | Very long chain fatty acid | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | A class of dietary fatty acids that have an alkyl chain length above 21 carbon atoms. |
C0000545 | has_gdc_value | C1254351 | eicosapentaenoic acid | Pharmacologic Substance | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | Any natural, endogenously-derived, synthetic or semi-synthetic compound with pharmacologic activity. A pharmacologic substance has one or more specific mechanism of action(s) through which it exerts one or more effect(s) on the human or animal body. They can be used to potentially prevent, diagnose, treat or relieve sy... |
C0000545 | is_target | C1565860 | eicosapentaenoic acid | PTGS2 protein, human | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | Prostaglandin G/H synthase 2 (604 aa, ~69 kDa) is encoded by the human PTGS2 gene. This protein plays a role in prostaglandin metabolism. |
C0000545 | is_target | C1567332 | eicosapentaenoic acid | CASP3 protein, human | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | Caspase-3 (277 aa, ~31 kDa) is encoded by the human CASP3 gene. This protein is involved in the mediation of proteolysis and the activation of apoptosis. |
C0000545 | subset_includes_concept | C3899741 | eicosapentaenoic acid | CTRP Terminology | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | Terminology that is used to support NCI's Clinical Trials Reporting Program (CTRP), a database that captures the required reporting data for all NCI-sponsored clinical trials. |
C0000545 | subset_includes_concept | C3899744 | eicosapentaenoic acid | CTRP Agent Terminology | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | A subset of terminology about pharmacologic substances and formulations that are currently being used or tested in clinical trials for the treatment of cancer, cancer-related conditions and chemo/radiotherapy-related side effects. |
C0000545 | subset_includes_concept | C4288628 | eicosapentaenoic acid | NCIt Antineoplastic Agent Terminology | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | A terminology subset in NCI Thesaurus (NCIt) containing any agent that has known or potential antineoplastic activity. The subset includes FDA approved antineoplastic agents, agents that either are or once were in clinical trial (CT) specifically for their antineoplastic activity as well as some additional investigatio... |
C0000545 | subset_includes_concept | C4684827 | eicosapentaenoic acid | CTRP Biomarker Terminology | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | A set of terms that is comprised of the biomarkers referenced in NCI-sponsored clinical trials. |
C0000545 | subset_includes_concept | C4763808 | eicosapentaenoic acid | GDC Terminology | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | Terminology that supports the Genomic Data Commons (GDC). |
C0000545 | subset_includes_concept | C4763809 | eicosapentaenoic acid | GDC Therapeutic Agent Terminology | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | null |
C0000545 | subset_includes_concept | C5447243 | eicosapentaenoic acid | NCI Drug Dictionary Terminology | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | Terminology created to support the National Cancer Institute (NCI) Drug Dictionary. |
C0000545 | subset_includes_concept | C5447840 | eicosapentaenoic acid | GDC Value Terminology | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | Terminology that supports the values for properties in the Genomic Data Commons (GDC) data model. |
C0000545 | used_for | C0015689 | eicosapentaenoic acid | omega-3 fatty acids | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | A group of unsaturated fatty acids occurring mainly in fish oils, with three double bonds at particular positions in the hydrocarbon chain. |
C0000545 | has_inactive_ingredient | C0793653 | eicosapentaenoic acid | salicylic acid 20 MG/ML Topical Solution | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | null |
C0000545 | has_inactive_ingredient | C0974918 | eicosapentaenoic acid | benzoyl peroxide 25 MG/ML Topical Cream | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | null |
C0000545 | has_active_ingredient | C2724684 | eicosapentaenoic acid | FOLIC ACID 1 mg / PYRIDOXINE HYDROCHLORIDE 12.5 mg / CYANOCOBALAMIN 500 ug / OMEGA-3 FATTY ACIDS 500 mg / DOCONEXENT 350 mg / ICOSAPENT 35 mg / .BETA.-SITOSTEROL 200 mg ORAL CAPSULE, COATED [BP Vit 3] | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | null |
C0000545 | has_active_moiety | C2724684 | eicosapentaenoic acid | FOLIC ACID 1 mg / PYRIDOXINE HYDROCHLORIDE 12.5 mg / CYANOCOBALAMIN 500 ug / OMEGA-3 FATTY ACIDS 500 mg / DOCONEXENT 350 mg / ICOSAPENT 35 mg / .BETA.-SITOSTEROL 200 mg ORAL CAPSULE, COATED [BP Vit 3] | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | null |
C0000545 | has_active_ingredient | C3162628 | eicosapentaenoic acid | docosahexaenoic acid 250 MG / eicosapentaenoic acid 0.625 MG Oral Capsule | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | null |
C0000545 | has_active_moiety | C3162628 | eicosapentaenoic acid | docosahexaenoic acid 250 MG / eicosapentaenoic acid 0.625 MG Oral Capsule | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | null |
C0000545 | has_active_ingredient | C3163069 | eicosapentaenoic acid | Nestabs DHA, Prenatal Multivitamins with Folic Acid 1 mg oral kit | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | null |
C0000545 | has_active_moiety | C3163069 | eicosapentaenoic acid | Nestabs DHA, Prenatal Multivitamins with Folic Acid 1 mg oral kit | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | null |
C0000545 | has_active_moiety | C3486025 | eicosapentaenoic acid | icosapent ethyl 1000 MG Oral Capsule | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | null |
C0000545 | has_active_moiety | C3486031 | eicosapentaenoic acid | icosapent ethyl 1000 MG Oral Capsule [Vascepa] | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | null |
C0000545 | has_active_ingredient | C3645065 | eicosapentaenoic acid | ICOSAPENT 40 mg / ASCORBIC ACID 90 mg / CHOLECALCIFEROL 220 [iU] / .ALPHA.-TOCOPHEROL ACETATE, DL- 10 [iU] / PYRIDOXINE HYDROCHLORIDE 26 mg / FOLIC ACID 400 ug / 5-METHYLTETRAHYDROFOLIC ACID 600 ug / CYANOCOBALAMIN 13 ug / BIOTIN 280 ug / CALCIUM FORMATE 155 mg / FERROUS ASPARTO GLYCINATE 18 mg / POTASSIUM IODIDE 150 u... | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | null |
C0000545 | has_active_moiety | C3645065 | eicosapentaenoic acid | ICOSAPENT 40 mg / ASCORBIC ACID 90 mg / CHOLECALCIFEROL 220 [iU] / .ALPHA.-TOCOPHEROL ACETATE, DL- 10 [iU] / PYRIDOXINE HYDROCHLORIDE 26 mg / FOLIC ACID 400 ug / 5-METHYLTETRAHYDROFOLIC ACID 600 ug / CYANOCOBALAMIN 13 ug / BIOTIN 280 ug / CALCIUM FORMATE 155 mg / FERROUS ASPARTO GLYCINATE 18 mg / POTASSIUM IODIDE 150 u... | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | null |
C0000545 | has_active_moiety | C3667473 | eicosapentaenoic acid | BIOTIN 280 ug / CALCIUM CARBONATE 80 mg / FERROUS ASPARTO GLYCINATE 9 mg / IRON 9 mg / POTASSIUM IODIDE 150 ug / MAGNESIUM OXIDE 25 mg / DOCONEXENT 350 mg / LOWBUSH BLUEBERRY 25 mg / LEVOMEFOLIC ACID 600 ug / ASCORBIC ACID 60 mg / CHOLECALCIFEROL 1000 [iU] / .ALPHA.-TOCOPHEROL ACETATE, DL- 10 [iU] / PYRIDOXINE HYDROCHL... | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | null |
C0000545 | has_active_ingredient | C3811624 | eicosapentaenoic acid | docosaenoic acid 300 MG / eicosapentaenoic acid 0.75 MG Oral Capsule | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | null |
C0000545 | has_active_moiety | C3811624 | eicosapentaenoic acid | docosaenoic acid 300 MG / eicosapentaenoic acid 0.75 MG Oral Capsule | Important polyunsaturated fatty acid found in fish oils. It serves as the precursor for the prostaglandin-3 and thromboxane-3 families. A diet rich in eicosapentaenoic acid lowers serum lipid concentration, reduces incidence of cardiovascular disorders, prevents platelet aggregation, and inhibits arachidonic acid conve... | null |
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