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C0000744
inverse_isa
C5680814
Abetalipoproteinemia
Rare hereditary metabolic disease with peripheral neuropathy
An autosomal recessive disorder of lipid metabolism. It is caused by mutation of the microsomal triglyceride transfer protein that catalyzes the transport of lipids (TRIGLYCERIDES; CHOLESTEROL ESTERS; PHOSPHOLIPIDS) and is required in the secretion of BETA-LIPOPROTEINS (low density lipoproteins or LDL). Features includ...
null
C0000744
inverse_isa
C5680981
Abetalipoproteinemia
Genetic intestinal disease due to fat malabsorption
An autosomal recessive disorder of lipid metabolism. It is caused by mutation of the microsomal triglyceride transfer protein that catalyzes the transport of lipids (TRIGLYCERIDES; CHOLESTEROL ESTERS; PHOSPHOLIPIDS) and is required in the secretion of BETA-LIPOPROTEINS (low density lipoproteins or LDL). Features includ...
null
C0000744
inverse_isa
C5681332
Abetalipoproteinemia
Neurometabolic disease
An autosomal recessive disorder of lipid metabolism. It is caused by mutation of the microsomal triglyceride transfer protein that catalyzes the transport of lipids (TRIGLYCERIDES; CHOLESTEROL ESTERS; PHOSPHOLIPIDS) and is required in the secretion of BETA-LIPOPROTEINS (low density lipoproteins or LDL). Features includ...
null
C0000744
inverse_isa
C5681517
Abetalipoproteinemia
Autosomal recessive metabolic cerebellar ataxia
An autosomal recessive disorder of lipid metabolism. It is caused by mutation of the microsomal triglyceride transfer protein that catalyzes the transport of lipids (TRIGLYCERIDES; CHOLESTEROL ESTERS; PHOSPHOLIPIDS) and is required in the secretion of BETA-LIPOPROTEINS (low density lipoproteins or LDL). Features includ...
null
C0000744
inverse_isa
C5681665
Abetalipoproteinemia
Metabolic disease with cataract
An autosomal recessive disorder of lipid metabolism. It is caused by mutation of the microsomal triglyceride transfer protein that catalyzes the transport of lipids (TRIGLYCERIDES; CHOLESTEROL ESTERS; PHOSPHOLIPIDS) and is required in the secretion of BETA-LIPOPROTEINS (low density lipoproteins or LDL). Features includ...
null
C0000744
inverse_isa
C5681745
Abetalipoproteinemia
Intestinal disease due to fat malabsorption
An autosomal recessive disorder of lipid metabolism. It is caused by mutation of the microsomal triglyceride transfer protein that catalyzes the transport of lipids (TRIGLYCERIDES; CHOLESTEROL ESTERS; PHOSPHOLIPIDS) and is required in the secretion of BETA-LIPOPROTEINS (low density lipoproteins or LDL). Features includ...
null
C0000744
mapped_from
C0020623
Abetalipoproteinemia
Hypolipoproteinemias
An autosomal recessive disorder of lipid metabolism. It is caused by mutation of the microsomal triglyceride transfer protein that catalyzes the transport of lipids (TRIGLYCERIDES; CHOLESTEROL ESTERS; PHOSPHOLIPIDS) and is required in the secretion of BETA-LIPOPROTEINS (low density lipoproteins or LDL). Features includ...
Conditions with abnormally low levels of LIPOPROTEINS in the blood. This may involve any of the lipoprotein subclasses, including ALPHA-LIPOPROTEINS (high-density lipoproteins); BETA-LIPOPROTEINS (low-density lipoproteins); and PREBETA-LIPOPROTEINS (very-low-density lipoproteins).
C0000744
mapped_from
C0154251
Abetalipoproteinemia
Lipid Metabolism Disorders
An autosomal recessive disorder of lipid metabolism. It is caused by mutation of the microsomal triglyceride transfer protein that catalyzes the transport of lipids (TRIGLYCERIDES; CHOLESTEROL ESTERS; PHOSPHOLIPIDS) and is required in the secretion of BETA-LIPOPROTEINS (low density lipoproteins or LDL). Features includ...
Pathological conditions resulting from abnormal anabolism or catabolism of lipids in the body.
C0000754
associated_with
C0001193
Congenital abnormal fusion
Apert syndrome
null
An autosomal dominant inherited type of acrocephalosyndactyly caused by mutations in the FGFR2 gene. It is characterized by early closure of the sutures between the skull bones, bulging eyes, low-set ears, fusion of the second, third, and forth fingers, and fusion of the toes.
C0000754
associated_with
C0016873
Congenital abnormal fusion
Fused Teeth
null
Two teeth united during development by the union of their tooth germs; the teeth may be joined by the enamel of their crowns, by their root dentin, or by both.
C0000754
associated_with
C0022738
Congenital abnormal fusion
Klippel-Feil Syndrome
null
A syndrome characterised by a low hairline and a shortened neck resulting from a reduced number of vertebrae or the fusion of multiple hemivertebrae into one osseous mass.
C0000754
associated_with
C0079541
Congenital abnormal fusion
Holoprosencephaly
null
Anterior midline brain, cranial, and facial malformations resulting from the failure of the embryonic prosencephalon to undergo segmentation and cleavage. Alobar prosencephaly is the most severe form and features anophthalmia; cyclopia; severe INTELLECTUAL DISABILITY; CLEFT LIP; CLEFT PALATE; SEIZURES; and microcephaly...
C0000754
associated_with
C0152233
Congenital abnormal fusion
Congenital ankyloblepharon
null
A congenital abnormality in which the margins of the upper and lower eyelids are fused together by bands of tissue.
C0000754
associated_with
C0158736
Congenital abnormal fusion
Syndactyly of fingers with fusion of bones
null
Webbing or fusion of the fingers, involving soft parts and including fusion of individual finger bones. [https://orcid.org/0009-0006-4530-3154]
C0000754
associated_with
C0158738
Congenital abnormal fusion
Syndactyly of toes with fusion of bones
null
Webbing or fusion of the toes, involving soft parts and including fusion of individual bones of the toes. Bony fusions are referred to as bony" Syndactyly if the fusion occurs in a tibial-fibular axis. Fusions of bones of the toes in a proximo-distal axis are referred to as "Symphalangism"." [https://orcid.org/0009-000...
C0000754
associated_with
C0158761
Congenital abnormal fusion
Radioulnar Synostosis
null
An abnormal osseous union (fusion) between the radius and the ulna. [https://orcid.org/0000-0002-0736-9199]
C0000754
associated_with
C0221353
Congenital abnormal fusion
Horseshoe Kidney
null
Congenital fusion of two kidneys in the lower midline.
C0000754
associated_with
C0265242
Congenital abnormal fusion
Otocephaly
null
A fatal, congenital, anatomic defect of the head characterised by a total or near total absence of the lower jaw, resulting in the union or close approach of the ears on the ventral side of the neck.
C0000754
associated_with
C0265651
Congenital abnormal fusion
Astragaloscaphoid synostosis
null
null
C0000754
associated_with
C0265652
Congenital abnormal fusion
Calcaneonavicular bar
null
null
C0000754
associated_with
C0265653
Congenital abnormal fusion
Coalition of calcaneus
null
null
C0000754
associated_with
C0265654
Congenital abnormal fusion
Tarsal Coalition
null
Congenital, complete or partial fusion of the TARSAL BONES of the foot. PES PLANUS is usually a feature.
C0000754
associated_with
C0265678
Congenital abnormal fusion
Congenital fusion of spine
null
null
C0000754
associated_with
C0265682
Congenital abnormal fusion
Sacralization of lumbar vertebra
null
null
C0000754
associated_with
C0265685
Congenital abnormal fusion
Congenital fusion of sacroiliac joint
null
null
C0000754
associated_with
C0265695
Congenital abnormal fusion
Congenital fusion of ribs
null
Complete or partial merging of adjacent ribs. [https://orcid.org/0000-0002-0736-9199]
C0000754
associated_with
C0265782
Congenital abnormal fusion
Unilobar lung
null
null
C0000754
associated_with
C0265850
Congenital abnormal fusion
Fused commissures of mitral valve
null
null
C0000754
associated_with
C0266033
Congenital abnormal fusion
Gemination of teeth
null
The development of two teeth from a single tooth bud, leading to a larger fused tooth. [PMID:18167487]
C0000754
associated_with
C0266096
Congenital abnormal fusion
Synchilia
null
null
C0000754
associated_with
C0266305
Congenital abnormal fusion
Fused Kidney
null
Congenital fusion of two kidneys.
C0000754
associated_with
C0266361
Congenital abnormal fusion
Hermaphroditism, True
null
An historical term for conditions of sexual ambiguity in which the individual possesses gonadal tissues of both sexes.
C0000754
associated_with
C0266419
Congenital abnormal fusion
Synechia vulvae
null
Synechia vulvae (adhesions of the labia minora) are characterized by a complete or partial fusion of the labia minora in the midline. [PMID:17364294, PMID:29262197]
C0000754
associated_with
C0266428
Congenital abnormal fusion
Congenital fusion of testis
null
null
C0000754
associated_with
C0266602
Congenital abnormal fusion
Congenital fusion of ossicles of ear
null
null
C0000754
associated_with
C0266636
Congenital abnormal fusion
Splenogonadal fusion
null
A rare, non-syndromic visceral malformation characterized by an abnormal, continuous or discontinuous attachment of the spleen to the gonad, epididymis or vas. Continuous type has a direct connection between spleen and the gonad, whereas discontinuous type indicates gonadal tissue fused with an accessory spleen or ecto...
C0000754
associated_with
C0431863
Congenital abnormal fusion
Carpal synostosis
null
Synostosis (bony fusion) involving one or more bones of the carpus (scaphoid, lunate, triquetrum, trapezium, trapezoid, capitate, hamate, pisiform). [https://orcid.org/0000-0002-0736-9199]
C0000754
associated_with
C0431878
Congenital abnormal fusion
Symbrachydactyly
null
null
C0000754
associated_with
C0685210
Congenital abnormal fusion
Congenital abnormal fusion of palatine bone
null
null
C0000754
associated_with
C0685217
Congenital abnormal fusion
Congenital abnormal fusion of zygomatic bone
null
null
C0000754
associated_with
C0685223
Congenital abnormal fusion
Congenital abnormal fusion of nasal bone
null
null
C0000754
associated_with
C0685231
Congenital abnormal fusion
Congenital abnormal fusion of lacrimal bone
null
null
C0000754
associated_with
C0685245
Congenital abnormal fusion
Congenital abnormal fusion of vomer
null
null
C0000754
associated_with
C0685252
Congenital abnormal fusion
Congenital abnormal fusion of premaxilla
null
null
C0000754
associated_with
C0685261
Congenital abnormal fusion
Congenital abnormal fusion of alisphenoid bone
null
null
C0000754
associated_with
C0685269
Congenital abnormal fusion
Congenital abnormal fusion of basisphenoid bone
null
null
C0000754
associated_with
C0685277
Congenital abnormal fusion
Congenital abnormal fusion of presphenoid bone
null
null
C0000754
associated_with
C0685285
Congenital abnormal fusion
Congenital abnormal fusion of basioccipital bone
null
null
C0000754
associated_with
C0685293
Congenital abnormal fusion
Congenital abnormal fusion of exoccipital bone
null
null
C0000754
associated_with
C0685301
Congenital abnormal fusion
Congenital abnormal fusion of supraoccipital bone
null
null
C0000754
associated_with
C0685310
Congenital abnormal fusion
Congenital abnormal fusion of interparietal bone
null
null
C0000754
associated_with
C0685319
Congenital abnormal fusion
Congenital abnormal fusion of parietal bone
null
null
C0000754
associated_with
C0685327
Congenital abnormal fusion
Congenital abnormal fusion of squamosal bone
null
null
C0000754
associated_with
C0685335
Congenital abnormal fusion
Congenital abnormal fusion of frontal bone
null
null
C0000754
associated_with
C0685344
Congenital abnormal fusion
Macromelia
null
null
C0000754
associated_with
C0685371
Congenital abnormal fusion
Congenital abnormal fusion of humerus
null
null
C0000754
associated_with
C0685377
Congenital abnormal fusion
Congenital abnormal fusion of radius
null
null
C0000754
associated_with
C0685386
Congenital abnormal fusion
Congenital abnormal fusion of ulna
null
null
C0000754
associated_with
C0685404
Congenital abnormal fusion
Congenital abnormal fusion of metacarpal bone
null
null
C0000754
associated_with
C0685416
Congenital abnormal fusion
Congenital abnormal fusion of forepaw phalanx
null
null
C0000754
associated_with
C0685419
Congenital abnormal fusion
Congenital abnormal fusion of femur
null
null
C0000754
associated_with
C0685425
Congenital abnormal fusion
Congenital abnormal fusion of fibula
null
null
C0000754
associated_with
C0685432
Congenital abnormal fusion
Congenital abnormal fusion of tibia
null
null
C0000754
associated_with
C0685442
Congenital abnormal fusion
Congenital abnormal fusion of calcaneus
null
null
C0000754
associated_with
C0685449
Congenital abnormal fusion
Congenital abnormal fusion of talus
null
null
C0000754
associated_with
C0685456
Congenital abnormal fusion
Congenital abnormal fusion of tarsal bone
null
null
C0000754
associated_with
C0685465
Congenital abnormal fusion
Congenital abnormal fusion of metatarsal bone
null
null
C0000754
associated_with
C0685478
Congenital abnormal fusion
Congenital abnormal fusion of hindpaw phalanx
null
null
C0000754
associated_with
C0685484
Congenital abnormal fusion
Congenital abnormal fusion of arch of cervical vertebra
null
null
C0000754
associated_with
C0685493
Congenital abnormal fusion
Congenital abnormal fusion of centrum of cervical vertebra
null
null
C0000754
associated_with
C0685494
Congenital abnormal fusion
Congenital abnormal fusion of centrum cartilage of cervical vertebra
null
null
C0000754
associated_with
C0685509
Congenital abnormal fusion
Congenital abnormal fusion of arch of thoracic vertebra
null
null
C0000754
associated_with
C0685518
Congenital abnormal fusion
Congenital abnormal fusion of centrum of thoracic vertebra
null
null
C0000754
associated_with
C0685519
Congenital abnormal fusion
Congenital abnormal fusion of centrum cartilage of thoracic vertebra
null
null
C0000754
associated_with
C0685534
Congenital abnormal fusion
Congenital abnormal fusion of arch of lumbar vertebra
null
null
C0000754
associated_with
C0685543
Congenital abnormal fusion
Congenital abnormal fusion of centrum of lumbar vertebra
null
null
C0000754
associated_with
C0685544
Congenital abnormal fusion
Congenital abnormal fusion of centrum cartilage of lumbar vertebra
null
null
C0000754
associated_with
C0685562
Congenital abnormal fusion
Congenital abnormal fusion of arch of sacral vertebra
null
null
C0000754
associated_with
C0685571
Congenital abnormal fusion
Congenital abnormal fusion of centrum of sacral vertebra
null
null
C0000754
associated_with
C0685572
Congenital abnormal fusion
Congenital abnormal fusion of centrum cartilage of sacral vertebra
null
null
C0000754
associated_with
C0685590
Congenital abnormal fusion
Congenital abnormal fusion of arch of caudal vertebra
null
null
C0000754
associated_with
C0685598
Congenital abnormal fusion
Congenital abnormal fusion of centrum of caudal vertebra
null
null
C0000754
associated_with
C0685636
Congenital abnormal fusion
Congenital abnormal fusion of rib cartilage
null
null
C0000754
associated_with
C0685646
Congenital abnormal fusion
Supernumerary fused sternebra
null
null
C0000754
associated_with
C0685653
Congenital abnormal fusion
Congenital abnormal fusion of ilium
null
null
C0000754
associated_with
C0685663
Congenital abnormal fusion
Congenital abnormal fusion of ischium
null
null
C0000754
associated_with
C0685682
Congenital abnormal fusion
Single naris
null
The presence of only a single nostril. [PMID:19152422]
C0000754
associated_with
C0685777
Congenital abnormal fusion
Congenital abnormal fusion of mandible
null
null
C0000754
associated_with
C0685782
Congenital abnormal fusion
Congenital abnormal fusion of maxilla
null
null
C0000754
associated_with
C0685814
Congenital abnormal fusion
Congenital abnormal fusion of liver lobes
null
null
C0000754
associated_with
C0685818
Congenital abnormal fusion
Congenital abnormal fusion of adrenal glands
null
null
C0000754
associated_with
C0685880
Congenital abnormal fusion
Congenital abnormal fusion of tympanic anulus
null
null
C0000754
associated_with
C0685895
Congenital abnormal fusion
Rhinocephaly
null
A congenital anatomic defect characterised by the presence of a proboscis-like nose located above the eyes, which are partially or completely fused.
C0000754
associated_with
C5848178
Congenital abnormal fusion
Symphalangism
null
null
C0000754
isa
C0332875
Congenital abnormal fusion
Congenital webbing
null
null
C0000754
isa
C0332876
Congenital abnormal fusion
Congenital fold
null
null
C0000754
isa
C0332877
Congenital abnormal fusion
Premature Closure
null
Fusion, stoppage, or loss of patency occurring before the usual or proper time.
C0000754
isa
C0332879
Congenital abnormal fusion
Congenital adhesion, NOS
null
null
C0000754
isa
C0332880
Congenital abnormal fusion
Congenital ankylosis, NOS
null
null
C0000754
isa
C0332881
Congenital abnormal fusion
Congenital pseudoarthrosis
null
null