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Prevalence of neurogenetic disorders in the North of England
Charcot–Marie–Tooth disease in Northern England
s2orc_citation_titles
SummaryThe changes in the status of the adenylic acid-creatine phosphate system and in glycogen, glucose, and lactate were investigated in canine kidneys during preservation in anaerobic and aerobic ischemia at normo- and hypothermia. For anaerobic ischemia, the kidneys were stored without additional measures; for aerobic ischemia, the ischemic kidneys were persufflated with gaseous O2 or gas mixtures containing O2 via the renal artery or vein (orthograde and retrograde aerobic ischemia respectively). Prior to preservation, the kidneys were flushed with cell-free perfusates.Changes in the metabolic status characteristic of anaerobic ischemia were a decrease in the tissue levels of ATP, creatine phosphate, glycogen, glucose, and the sum of adenine nucleotides, a transitory increase in ADP and AMP, and an increase in the tissue level of lactate. Hypothermia caused a retardation of the anaerobic alterations; the loss of ATP was slowed down by factors of 2 and 9.5 when the temperatures were lowered from 37° to 26° and 6°C, respectively.In aerobic ischemia with orthograde and retrograde persufflation of 100% O2 (persufflation pressure = PP 60 and 30 mm Hg), deviations from a regular metabolic status developed very slowly. While the ATP-level decreased to 50% of the control value within scarcely 30 min of anaerobic ischemia at 6°C, it was almost 48 h before a similar loss of ATP occurred during orthograde aerobic ischemia at 6°C. Reduction of O2 in the persufflation gas to 40 and 21 vol-% resulted in less adequate preservation of the metabolic status. Increasing PP to 100 mm Hg for orthograde persufflation had no effect. An increase in PP to 60 mm Hg for retrograde persufflation resulted in a further delay in the metabolic deterioration. The long-term preservation of a regular metabolic status or the slow deviation of the metabolic pattern from the normal range during ischemia with O2-persufflation indicates a significantly smaller energy deficit than during storage in anaerobic ischemia. It must be attributed to a sufficient aerobiosis in the aerobically ischemic kidney, during which organogenic substrates brought in by the initial perfusion are utilized.
In search for new techniques of renal preservation, kidneys were persufflatedin situ with gaseous O2 at a pressure of 90–100 mm Hg via their vascular system (orthograde aerobic ischemia). The results on post-ischemic function and blood flow, and on the changes in the renal tissue levels of the adenine nucleotides were compared to those obtained from kidneys ischemically stored without additional measures (anaerobic ischemia). The kidneys were stored for 4 hrs at 6°C. A contralateral nephrectomy was performed before the preservation period.
s2orc_abstract_citation
what sport did william mcdowell white give up on
William McDowell-White 13. Despite seemingly heading down the same career path as his father, William surprised many, when he decided to focus on basketball, and gave up playing football at the age of 15. He played at the Nike Hoop Summit in 2016. McDowell-White also attended Fresno State University, alongside his Older brother Darryl, in 2016. However, Will would ultimately be ruled academically ineligible to play for the university's team, the Bulldogs. After being ruled academically ineligible at Fresno State University, it was announced in December 2016, that McDowell-White had signed to play with the Sydney Kings, in the 2016–17 season of
paq
Malignant histiocytosis. A report of three cases.
Malignant histiocytosis: A reassessment of cases formerly classified as histiocytic neoplasms and review of the literature
s2orc_citation_titles
Make Mini Meatloaves
This meatloaf version is created using muffin pans instead of a regular loaf pan. Simple to make and delicious to eat. Here is how to make mini meatloaves.
wikihow
Nonlinear relationships between anxiety and visual processing of own and others’ faces in body dysmorphic disorder
The neurobiology of body dysmorphic disorder: A systematic review and theoretical model
s2orc_citation_titles
Embryonic DEVOURMENT release a new album later this year
Brutal Death Grind ' Embryonic Devourment ' recently completed all of the new album material , and is ready to release a new album as soon as the end of this year . Album entitled ' Reptilian Agenda ' will be released by ' Deepsend Records ' . The album in mixing and mastering by ' Colin Davis ' deal ever ' Vile ' . For the concept of this album , ' Embryonic Devourment ' take the point of view of humanoid reptiles that became extinct 1,000 years ago .
reddit_title_body
With grid expansion in China, many metropolitan power grids have been divided into partitions at 220kV to reduce the system short-circuit current and make the grid structure clearer. However, there are still a lot of problems with the current domestic (Chinese) grid partitioning. In contrast, urban power grids of developed countries are fully developed, and their partition operation experience can be reference for domestic urban power grids. In this paper, the grid partitioning situation of domestic cities, especially Shanghai power grid, is presented and analyzed. Then, similar work is done to analyze the grid partition status quo of New York and Tokyo of which grid partition features are prominent. Finally, the metropolitan power grid partition situation in China and abroad is comparatively analyzed to provide reference for the Chinese urban power grids. Keywords-metropolitan power grid; power grid partition; Shanghai grid; New York City grid; Tokyo grid
The paper analyzed the problems that the power flow,N-1 static security and short circuit current of Jiangsu grid are over limit in future years,brought forward recommended scheme of network partition of Jiangsu grid in 2006 and presented proposals on issues of network planning,power plant construction and configuration of security automation devices.
s2orc_abstract_citation
what does mba stand for at fox school of business and management
trading room and business simulation center, along with one of the longest stock tickers in the United States. Fox School of Business and Management The Richard J. Fox School of Business and Management is the business school of Temple University. Located in Philadelphia, the Fox School offers several Master of Business Administration programs (full-time MBA, part-time MBA, international MBA, executive MBA and online MBA); several other master's degree programs; and several Ph.D. programs, including in accountancy, finance, marketing, international business, entrepreneurship, management of information systems, risk management and insurance, strategic management, and sports. The school has some 6,500 students, 155
paq
Poor example for kids
Very negative book until you get to the end. Poor example for kids.
amazon_reviews
Do the Perfect Step Overs in Soccer
Ever wanted to know how Cristiano Ronaldo does his step-overs so quickly? Or how Joe Cole does it? Are you an aspiring soccer star? Well with these simple instructions you will be able to do the traditional step over in your sleep.
wikihow
What was snow patrol's first album?
What artic creature was snow patrol previously named after?
wikianswers
A shared approach to supporting remote observing for multiple observatories
Remote observing with the Keck Telescopes
s2orc_citation_titles
Are bert and ernie from sesame street a banana and and orange?
Where did bert and ernie from sesame street get their names?
wikianswers
this is sturdy and trustworthy
Boy, this is sturdy and trustworthy, and the tabs worked great. I do wish it were a little longer. However, I am still giving it 5 stars, as I think the length is pretty standard compared to its competitors. I would love it to cover more of the door. Still good!
amazon_reviews
Imagination: Lin Bai's Individualized Writing
The most noticeable phenomenon in female literature creation in the 1990s is "body writing" and the individualized writing developed on it. The female writing posture changed in thousand ways. As the representative writer of the female literature creation, Lin Bai endeavored to practice her in devitalized writing during that times. She made her novel language full of imagination on base of her own personal experience and her own memory.
s2orc_title_abstract
Who had a illegitimate son of a French noble who invaded England in 1066?
What group invaded england in 1066 AD?
wikianswers
who occupied the ryukyu islands after world war 2
History of the Ryukyu Islands grenades to the girls to allow them to commit suicide rather than be taken as prisoners. One of the Princess Lilies explained: "We had a strict imperial education, so being taken prisoner was the same as being a traitor. We were taught to prefer suicide to becoming a captive." Many students died saying, "Tennō Heika Banzai", which means "Long live the Emperor". After the war, the islands were occupied by the United States and were initially governed by the United States Military Government of the Ryukyu Islands from 1945 to 1950 when it was replaced by the United States Civil
paq
when did the anglican community arrive in the canary islands
Religion in the Canary Islands routes and its condition as a bridge of union between Europe, Africa and America motivated the establishment in the islands of merchants and merchants of various religions, including Jews and Protestants. The presence of Anglican communities in the archipelago dates back to the late sixteenth century, although it will be from the nineteenth century when it will take more boom. The first Anglican communities arrived in the Canary Islands were established mainly in the cities of Puerto de la Cruz, Santa Cruz de Tenerife, Las Palmas de Gran Canaria and to a lesser extent in Santa Cruz de La Palma.
paq
How to improve my aim and reaction time
Hello, can you advice me how to improve my aim and reaction time? I have 50 competitive wins and I am still Silver I. Is there any way to know if I have talent to CS:GO? Thanks
reddit_title_body
Vivianne Reding named 2006's 'villain of the internet'
.eu palaver tipped the scales European Commissioner Vivianne Reding is the internet's biggest villain of the year, according to UK internet service providers. She was given the title by the ISP Association (ISPA) in protest at the rules for registering a .eu domain name.…
agnews
david shakow is best known for his pioneering research on what disorder
David Shakow David Shakow (1901–1981) was an American psychologist. He is perhaps best known for his development of the Scientist-Practitioner Model (or "Boulder Model") of graduate training for clinical psychologists, adopted by the American Psychological Association in 1949. He also did pioneering research in schizophrenia, especially focusing on how deterioration and deficit results in the loss of normal functioning. His work helped to humanize those with schizophrenia, which was then seen largely as dangerous and untreatable. He is also known in the field for creating one of the first U.S. clinical psychology internship programs while he was at Worcester State
paq
Estimating sex ratios of loggerhead turtles in Brazil from pivotal incubation durations
A method of estimating natural sex ratios of hatchlings of species with temperature-dependent sexual differentiation from data on incubation durations is described. The method was applied to loggerhead turtles (Caretta caretta) nesting in Brazil. Data on incubation durations were collected from 11 nesting beaches monitored for up to six seasons. It was estimated that 82.5% of the loggerhead hatchlings produced were female. The strongly female-biased sex ratio in Brazil is similar to that found previously for loggerheads using beaches in the eastern U.S.A. This suggests that a female-biased hatchling sex ratio may be a feature of loggerhead populations.
s2orc_title_abstract
How was reconstruction efforts in the south affect the national elections after the civil war?
What were the results of the civil war and reconstruction?
wikianswers
Kengo Ishii ( born 2 April 1986 ) is a Japanese football player . He plays for Ehime .
Kengo Ishii is a Japanese footballer who currently plays for Ehime F.C. .
simplewiki
2nd workshop on software development governance (SDG)
Towards governance schemes for distributed software development projects
s2orc_citation_titles
Phase Transients in the Higher-Harmonic RF Systems For the ALS-U Proposal
Transient beam loading effects in harmonic rf systems for light sources
s2orc_citation_titles
Will a corn sanke eat crickets?
Does corn snakes eat crickets?
wikianswers
Can you machine-wash microfiber suede?
How do you wash microfiber in a washing machine?
wikianswers
Research progress in control and microbial infection of fresh-cut fruits and vegetables
Microbial infection is one of the most important factors influencing quality of fresh-cut fruits and vegetables.In this paper,the sources and species of microbial,which effect on physiology of fresh-cut fruits and vegetables,were reviewed.The control methods on microbial of fresh-cut fruits and vegetables were introduced at home and abroad.
s2orc_title_abstract
Split-Twig Figurines from Northern Arizona: New Radiocarbon Dates.
Late Holocene Climate Change and the Origin of the “Figurine Complex” In Grand Canyon, Arizona
s2orc_citation_titles
Pricing Disclosure: Crowdfunding’s Curious Conundrum
Crowdfunding: Motives, Definitions, Typology and Ethical Challenges
s2orc_citation_titles
what is the main toxicant of clitocybe rivulosa ( cl
consumption. The main toxin in "Clitocybe rivulosa" is muscarine, and thus the symptoms are those of muscarine poisoning, namely, greatly increased salivation, perspiration (sweating), and lacrimation (tear flow) within 15–30 minutes of ingestion. With large doses, these symptoms may be followed by abdominal pain, severe nausea, diarrhea, blurred vision, and labored breathing. Intoxication generally subsides within two hours. Death is rare, but may result from cardiac or respiratory failure in severe cases. The specific antidote is atropine. Clitocybe rivulosa Clitocybe rivulosa, commonly known as the false champignon or fool's funnel, is a poisonous basidiomycete fungus of the large genus "Clitocybe".
paq
// WatchLeaderSettings returns a watcher for observing changed to an application's // leader settings.
func (a *Application) WatchLeaderSettings() NotifyWatcher { docId := a.st.docID(leadershipSettingsKey(a.Name())) return newEntityWatcher(a.st, settingsC, docId) }
codesearch
Name seven reasons why someone voice sounds funny?
Reasons why someones voice might sound funny?
wikianswers
Watching MLG games seems really "erratic"
Does anyone one else feel like when they watch MLG scrims or the 5k that it was just really death after death and hard to keep track of where everyone was?
reddit_title_body
What is the lug nut torque spec for a PT Cruiser?
Lug nut torque specs for pt cruiser?
wikianswers
CRACK DETECTION AT CONCRETE CONSTRUCTION UNITS FROM PHOTOGRAMMETRIC DATA USING IMAGE PROCESSING PROCEDURES
Monitoring of concrete members using photogrammetry and image processing
s2orc_citation_titles
Does corona have sugar in it?
Is there sugar in corona?
wikianswers
What was ceasar chavez's childhood like?
What was cesar chavez education like?
wikianswers
Betsy ross's mom and dad 's names?
Betsy Ross's mom and dad's name?
wikianswers
Give an explicit formula for the affine map θ : R → R . . .?
Give an explicit formula for the affine map θ : R → R carrying [ S1 , S2 ]→ [t1 , t2] with θ(Si) = ti , i=1,2 . In particular, give a formula for the affine map taking [32,212] on to [0,100]. (Hint: θ(x) = λx +x0).
yahoo_title_question
High Pressure Interpass Rolling of Wire + Arc Additively Manufactured Titanium Components
Realization of A Multi-Sensor Framework for Process Monitoring of the Wire Arc Additive Manufacturing in Producing Ti6Al4V Parts
s2orc_citation_titles
what are the ncr test answers?
When he asks you who the most popular NCR president was, you answer Tandi. When asked where the original NCR capital was located, you answer Shady Sands. And when asked what the NCR's flag is emblazoned with, you answer a double-headed bear.
gooaq
Well written story of Oregon History
As a lover of Western and Oregon histroy I found this story to be factual to the area as I know it. The stroy line was well written and interesting.
amazon_reviews
Quality management certification on Farms Machineries Market
HOW TRACTORS TRADERS SEE THE ROMANIAN QUALITY MANAGEMENT SYSTEM
s2orc_citation_titles
What is common among a family of elements?
What do elements in the same familygroup have in common?
wikianswers
Go to outback instead
More rating for the restaurant instead of the cards. Spend your money on a better quality steak at outback instead. Also as a southerner with an accent I hate that they force everyone to "have an accent".
amazon_reviews
Why do mothers breastfeed?
Why should others breastfeed?
wikianswers
When betty smith wrote a tree grows in brooklyn what was she inspired by?
Why did Betty Smith write A Tree Grows In Brooklyn?
wikianswers
Infected acute myocardial infarct with rupture in systemic lupus erythematosus
Cardiac Rupture Following Acute Myocardial Infarction in Systemic Lupus Erythematosus: Case Report
s2orc_citation_titles
Warfarin time in therapeutic range and its impact on healthcare resource utilization and costs among patients with nonvalvular atrial fibrillation
Impact of Warfarin Persistence on Health-Care Utilization and Costs Among Patients With Atrial Fibrillation Managed in Anticoagulation Clinics in the United States
s2orc_citation_titles
Family Feud: The best, worst and most ridiculous moments
Following news that Family Feud has been cancelled, we take a look back at these stellar moments from the show's 100th episode anniversary. Family Feud has been the source of a lot of laughter since it came to New Zealand television screens. Here are some of the best (or worst, depending on how you look at it) answers on the show so far, starting with one from a celebrity episode featuring Hunt For the Wilderpeople's Julian Dennison. READ MORE: Family Feud Cancelled as Dai Goes Dancing What's Julian Dennison up to in his spare time? The question: Advertisement "Name an animal we eat, that would never eat us." The answer: : "A horse?" Is horse on the board? Dai: "Name an animal we eat, that would never eat us" Julian: "A horse?" Posted by Family Feud New Zealand on Monday, 23 May 2016 The best part about this is Julian's clearly just throwing the towel in by making his answer another question: a horse? Maybe. To be fair, there was that time a handful of British supermarket were discovered to be selling horse meat in the frozen section, so he's not entirely wrong. Oi, with the horses already The question: "Name a tall breed of dog." The answer: "A horse." Horse is Not a Dog Dai: "Name a tall breed of dog." Aurora: "A horse." Posted by Family Feud New Zealand on Sunday, 17 April 2016 The best part about this is Aurora knows it's wrong (she's not stupid), but she's just thought "hey, might as well". You never know, one of the 100 Kiwis surveyed may well have drawn a blank and written horse too. Either way, bonus points for having a crack at impersonating a horse. Well, you're not entirely wrong The question: "Give me a word that rhymes with jumper." The answer: "Jumper." Let's see if you can beat Heather's answer? Give us a word that rhymes with Jumper. Tune in tonight 5.30pm for more funny moments #familyfeudnz Posted by Family Feud New Zealand on Thursday, 18 February 2016 Clearly, Heather heard somewhere that confidence is key. Hey, if rappers can get away with rhyming by repeating the same word, why can't she? Just your finest mammal, please The question: "Name an animal beginning with M." The answer: "Mammal" Of Mammals and Mammal Milk Dai asks: "Name an animal beginning with M." Posted by Family Feud New Zealand on Thursday, 7 April 2016 Everything about this is great. But nothing more so than Ethan answering the question "what sort of milk comes from a mammal?", with "mammal milk". By the time they're done, mammal doesn't even sound like a real word anymore. Only in New Zealand, eh? The question: "Name something that gives you support." The answer: "Social welfare." Hilarious Social Welfare Moment This is literally the BEST answer we've had on Feud so far! Posted by Family Feud New Zealand on Tuesday, 8 March 2016 This one's the gift that keeps on giving. First of all, Ben seems pretty stoked with that answer and he should be. That's the kind of one liner a comic might work into a set. But also, not only does Dai find it hilarious, but he seems genuinely outraged when the answer doesn't come up on the board. Because once again, he's not wrong. Just what doors is the PM opening? The question: "Name a type of key." The answer: "I'm going to say... John." John Key Dai: "Name a type of key." Jakob: "I'm going to say.....John." Posted by Family Feud New Zealand on Monday, 21 March 2016 The best part about this is, while everyone's sitting around cracking up at Jakob's ridiculous answer, it turns out it isn't that ridiculous. Not only is "John Key" on the board, it's the second most popular answer. The ultimate wedding crasher The question: "Something you might take home [from a wedding]" The answer: "Bridesmaids." Paki and His Bridesmaids Dai asks: 'Name something you might take home from a wedding." and we are cracking up at Paki's answer! So good. Posted by Family Feud New Zealand on Wednesday, 4 May 2016 As Dai points out, what's funny about this is Paki makes a special effort to make it a plural - Bridesmaids, not just one. It's not technically on the board, but the sentiment's very much the same. On ya, Paki. Ya walked right into that one, Dai The question: "Besides an animal, name something that is hairy." The answer: "Dai Henwood." Dai Henwood is a Hairy Man And the 6th most popular answer is... Dai Henwood?! Posted by Family Feud New Zealand on Friday, 8 April 2016 Dai was the sixth most popular answer on the board. Need we say more? These women are out of control The question: "Name something that's hard to control." Answer one: "The wind." Answer two: "A car." Things are out of control We've had some surprising answers before, but none quite like this! #AnythingCanHappen Posted by Family Feud New Zealand on Wednesday, 8 June 2016 Sure, the weather is hard to control. If by "hard", you mean "impossible". And if you answered "car", then please, for us, stay off the roads. What's even better than these answers though, is the fact that Dai mocked both of them, only to discover they were on the board. Which leads us to our final moment: You may be wrong, but at least you're not alone The question: "Apart from Wellington, name a capital city." The answer: "Auckland." Since when was Auckland a capital city And this wasn't the only shocking answer of the night... Posted by Family Feud New Zealand on Monday, 13 June 2016 Janet starts out confident, only realising her mistake when the audience's laughter fails to let up. But the joke's on all of us, because it turned out a bunch of other people also think Auckland's a capital city, and it was on the board. You've got to love a quiz show where you're only as right or wrong as the people around you.
ccnews
Legality of bringing a butterfly knife into the United States
I was wondering if it is legal to bring two butterfly knives into the States.(From Russia into Colorado, stopping in Germany for a week) I've searched for an answer but still haven't figured out if customs actually seizes them or not. If it isn't legal, could I perhaps mail them in?
reddit_title_body
Found this camera at work...
I work at a recycling depot and found this camera in with the tin cans and decided to take it home.. Would anyone be able to give me some info on it. and what i would need to use it... if anything special
reddit_title_body
What is the average height of a pool table?
What is the height of a regulation pool table?
wikianswers
Adaptive power controlled MAC protocol in mobile ad hoc networks
We first propose two power controlled MAC protocols which constrain the transmission power of the current packet depending on the transmission and received powers of the preceding packet. We determine the optimal level of over-compensation for different operating scenarios. Then we propose a fully adaptive power control (APC) protocol which is shown to yield significant improvement in system performance.
s2orc_title_abstract
HTC Mail app reverts to Plain Text on its own
Anyone else experiencing this? Set your mail app to HTML format in the settings, and then randomly later it reverts to Plain Text. It also reverts to the setting not to download any attachments. There's a thread on XDA about it, but no solutions as yet.
reddit_title_body
Is a turtle a reptile or mammal or amphibian?
Is a turtle a mammal reptile or amphibian?
wikianswers
How many boyfriends does demi lovato?
How many boyfriend had demi lovato had?
wikianswers
Advances in the development of an antifertility vaccine
Possibility and potential of a vaccine against human chorionic gonadotropin for family planning
s2orc_citation_titles
Drug trials with Monanema martini: effect on the adult worms, the dermal microfilariae and the natural murid host
Ivermectin and moxidectin in two filarial systems: resistance of Monanema martini; inhibition of Litomosoides sigmodontis insemination.
s2orc_citation_titles
how to find your bank routing number without checks?
You can also find the routing number by logging into your bank account online and checking your bank statement. If you don't have access to either, you can get your routing number by contacting the bank directly.
gooaq
Cluster-cluster aggregations of superparamagnetic particles in a rotational magnetic field.
Structural Organization in Magnetic Fluids with Magnetized Aggregates in Rotating Magnetic Field
s2orc_citation_titles
Successful treatment of congestive heart failure with concomitant administration of tolvaptan to enhance the effects of furosemide
A new paradigm for the treatment of volume overload in heart failure-combined effect of tolvaptan with furosemide
s2orc_citation_titles
@param File $file Send the raw file to the output interface (chunked by blockSize).
protected function outputRaw(File $file) { $fh = $file->getFilehandle(); $crc = $file->isSmooth() ? hash_init('crc32b') : FALSE; $size = 0; while (TRUE) { $data = fread($fh, $this->blockSize); $chunkLength = $data === FALSE ? 0 : strlen($data); if ($chunkLength == 0) break; $size += $chunkLength; $crc && hash_update($crc, $data); $this->output($data); } $file->setSize($size); $file->setDeflatedSize($size); if ($crc) $file->setRawCrc(hash_final($crc, TRUE)); fclose($fh); }
codesearch
Depressive symptomatology and fall risk among community-dwelling older adults
The association between depressive symptoms and fall accidents among middle-aged and elderly people in China
s2orc_citation_titles
What metals aern't magnetic?
2 metals which are not magnetic?
wikianswers
where will linknyc be located in the uk
agency Primesight, is also planning to install up to 850 Links in the United Kingdom, including in London, beginning in 2017. The LinkUK kiosks, as they will be called, are similar to the LinkNYC kiosks in New York City. These Links will replace some of London's iconic telephone booths due to these booths' age. The first hundred Links would be installed in the borough of Camden. The Links will have tablets, but they will lack web browsing capabilities due to the problems that LinkNYC faced in enabling the tablet browsers. In early 2016, Intersection announced that it could install about
paq
Fractal Friday - 01/04/13 - ALL NIGHT!!
**Who** * Anyone who wants to get some Fractals done. * Anyone who needs to get their Monthly Achievement completed. **What** Fractals!! **When** 01/04/13 - All Night!! **Where** Just be on and we'll coordinate it all. **Why** * Monthly. * Because it's fun!
reddit_title_body
Catfish (Ictalurus punctatus) cone horizontal cells contain N-methyl-d-aspartate (NMDA) receptors, the function of which has yet to be determined. In the present study, we have examined the effect of NMDA receptor activation on voltage-gated ion channel activity. NMDA receptor activation produced a long-term downregulation of voltage-gated sodium and calcium currents but had no effect on the delayed rectifying potassium current. NMDA's effect was eliminated in the presence of AP-7. To determine whether NMDA receptor activation had functional implications, isolated catfish cone horizontal cells were current clamped to mimic the cell's physiological response. When horizontal cells were depolarized, they elicited a single depolarizing overshoot and maintained a depolarized steady state membrane potential. NMDA reduced the amplitude of the depolarizing overshoot and increased the depolarized steady-state membrane potential. Both effects of NMDA were eliminated in the presence of AP-7. These results support the hypothesis that activation of NMDA receptors in catfish horizontal cells may affect the type of visual information conveyed through the distal retina.
1. Bifurcation theory is used to study properties of nonlinear analytical and computational models of isolated retinal horizontal cells. The analytical model is based on the published data of Shingai and Christensen describing steady-state I-V characteristics of horizontal cells isolated from catfish (Ictalurus punctatus) retina. The computational model is based on I-V characteristics of distinct macroscopic membrane currents observed in horizontal cells isolated from goldfish (Carassius auratus) retina. Slow-model dynamics are analyzed assuming that excitatory processes occur rapidly with respect to the time course of inactivation of the inward Ca2+ and outward K+ currents. 2. A global bifurcation diagram plotting the location and stability properties of critical points as a function of photoreceptor-evoked horizontal-cell postsynaptic membrane conductance Gsyn is derived for the analytical model. The automated bifurcation analysis software AUTO is used to compute global bifurcation diagrams for the computational model. Bifurcation diagrams exhibit a bistable regime at small Gsyn values characterized by two stable and one unstable critical point and a monostable regime at larger Gsyn values characterized by a single globally attracting stable critical point. The transition between bistable and monostable behavior occurs at a Gsyn value of roughly 0.9 nS for the computational model and 1.7 nS for the analytical model. Estimates of horizontal-cell glutamate-channel conductance suggest that this transition corresponds to the activation of as few as 400-700 glutamate channels. Dark-evoked release of neurotransmitter from photoreceptors may therefore set horizontal-cell synaptic conductance Gsyn to a value within the monostable regime. 3. Photoreceptor-evoked horizontal-cell membrane conductance, total Ca2+ channel conductance, and inactivation of the inward Ca2+ current are shown to be the major factors controlling the bifurcation structure of the computational model. Inactivation of the inward Ca2+ current is required to account for the dark resting potential of horizontal cells as well as light-evoked hyperpolarizing responses. Inactivation of the outward K+ current has little effect on model properties. 4. Isolated horizontal cells generate Ca2+ action potentials whereas cells in the intact retina normally do not. Simple procedures for modeling the slow dynamics of isolated horizontal-cell Ca2+ action potentials are described.(ABSTRACT TRUNCATED AT 400 WORDS)
s2orc_abstract_citation
Is racing heartbeat a side effect of Lotrel?
"Racing" heartbeat is not a usual or common known side effects of Lotrel but rather it could be a primary symptom of overdosage which goes along with a sudden drop of blood pressure. You need to see a doctor immediately for reevaluation of his dosage treatment.♥
yahoo_title_answer
what is the title of the 6 part of jacki apple's montage of political
Jacki Apple airtime to address their fellow citizens on “what should we aspire to and how we should get there" as if they were running for President. The compilation of voices from across the political spectrum was orchestrated and edited by Apple into a multilayered montage of views on education, the environment, racism, greed, government, the power elite, spiritual values, and broadcast in October 1992. "A Leap of Faith" (Part 6), a collaboration with Keith Antar Mason produced in the aftermath of the Los Angeles uprisings, is a poetic exchange between the two artists- one white and one black-- "born in America
paq
Iranian Environmentalism: Nationhood, Alternative Natures, and the Materiality of Objects
Management of the Environment (mohit-e zist) An Ethnography of Islam and Environmental Politics in Iran
s2orc_citation_titles
Short backfire antenna with concentric sleeves for highly sensitive radio astronomical receivers
Short backfire antennas for wireless LAN applications at millimeter-waves
s2orc_citation_titles
Skin Manifestations Associated With Mantle Cell Lymphoma: a Case Report
Insect bite-like reaction associated with mantle cell lymphoma: clinicopathological, immunopathological, and molecular studies.
s2orc_citation_titles
What event within the heart causes the AV valves to open?
What event within the heart cause the valves to opens?
wikianswers
which is the only member of the eu not to have a rome i regulation
Rome I Regulation The Rome I Regulation (Regulation (EC) No 593/2008 of the European Parliament and of the Council of 17 June 2008 on the law applicable to contractual obligations) is a regulation which governs the choice of law in the European Union. It is based upon and replaces the Convention on the Law Applicable to Contractual Obligations 1980. The Rome I Regulation can be distinguished from the Brussels Regime which determines which court can hear a given dispute, as opposed to which law it should apply. The regulation applies to all EU member states except Denmark, which has an
paq
An Optimal Selection Method of Manufacturing Resources in Cloud Environment
Cloud Manufacturing allows geographically separated factories to cooperate for finishing one manufacturing task with less time, less cost, higher quality. The key issue is to achieve the optimal combination of manufacturing resources in cloud. In this paper, the constraint characteristics among manufacturing resources in cloud environment are analyzed, involving the attributes of manufacturing resources and constraints relationship among them. Based on Rough Set theory, an optimal selection method for manufacturing resources in the cloud manufacturing environment is proposed, along with its implementation framework and processing approach. A case study is demonstrated and discussed to validate the proposed method.
s2orc_title_abstract
Bifidobacterium in the gut microbiota confer resilience to chronic social defeat stress in mice
Possible role of the gut microbiota–brain axis in the antidepressant effects of (R)-ketamine in a social defeat stress model
s2orc_citation_titles
Abstract Objective To systematically review the outcomes of tongue-tie division procedures in patients with ankyloglossia with the goal of (1) deriving clinically oriented insights into the effect of tongue-tie division procedures and (2) identifying needs in knowledge to stimulate further research. Data sources Medline, EMBASE, and Cochrane databases were searched without any limitations, for studies published between 1966 and June 2012. Review methods Studies were included (level 4 evidence or above) if subjects of any age had ankyloglossia and underwent tongue-tie release. Outcome measures of interest were any subjective or objective measures of breastfeeding and speech outcomes, or reports of adverse events. Results In all, 378 abstracts were generated from the literature searches; 20 studies met the criteria for data extraction and analysis. Of those, 15 studies were observational and 5 were randomized controlled trials. Tongue-tie division provided objective improvements in the following: LATCH scores (3 studies); SF-MPQ index (2 studies); IBFAT (1 study); milk production and feeding characteristics (3 studies); and infant weight gain (1 study). Subjective improvements were also noted in maternal perception of breastfeeding (14 studies) and maternal pain scores (4 studies). No definitive improvements in speech function were reported. The only significant adverse events were recurrent tongue-ties that required repeat procedures. Conclusion Ankyloglossia is a well-tolerated procedure that provides objective and subjective benefits in breastfeeding; however, there was a limited number of studies available with quality evidence. There are no significant data to suggest a causative association between ankyloglossia and speech articulation problems. Aspects of ankyloglossia that would benefit from further research are described, and recommendations for tongue-tie release candidacy criteria are provided.
BACKGROUND AND OBJECTIVE ::: Children with ankyloglossia, an abnormally short, thickened, or tight lingual frenulum, may have restricted tongue mobility and sequelae, such as speech and feeding difficulties and social concerns. We systematically reviewed literature on feeding, speech, and social outcomes of treatments for infants and children with ankyloglossia. ::: ::: ::: METHODS ::: Medline, PsycINFO, Cumulative Index of Nursing and Allied Health Literature, and Embase were searched. Two reviewers independently assessed studies against predetermined inclusion/exclusion criteria. Two investigators independently extracted data on study populations, interventions, and outcomes and assessed study quality. ::: ::: ::: RESULTS ::: Two randomized controlled trials, 2 cohort studies, and 11 case series assessed the effects of frenotomy on feeding, speech, and social outcomes. Bottle feeding and social concerns, such as ability to use the tongue to eat ice cream and clean the mouth, improved more in treatment groups in comparative studies. Supplementary bottle feedings decreased over time in case series. Two cohort studies reported improvement in articulation and intelligibility with treatment. Other benefits were unclear. One randomized controlled trial reported improved articulation after Z-frenuloplasty compared with horizontal-to-vertical frenuloplasty. Numerous noncomparative studies reported speech benefits posttreatment; however, studies primarily discussed modalities, with outcomes including safety or feasibility, rather than speech. We included English-language studies, and few studies addressed longer-term speech, social, or feeding outcomes; nonsurgical approaches, such as complementary and alternative medicine; and outcomes beyond infancy, when speech or social concerns may arise. ::: ::: ::: CONCLUSIONS ::: Data are currently insufficient for assessing the effects of frenotomy on nonbreastfeeding outcomes that may be associated with ankyloglossia.
s2orc_abstract_citation
New uniqueness results for fractional differential equation with dependence on the first order derivative
In this paper, we study the uniqueness of solutions for a fractional differential equation with dependence on the first order derivative. By means of Banach’s contraction mapping principle and a weighted norm in product space, sufficient conditions for the uniqueness of solutions are investigated. An example is given to illustrate the main results.
s2orc_title_abstract
Radiation Effects on Unsteady MHD Free Convective Couette Flow of Heat Generation/Absorbing Fluid
Combined Effects of Hall Current and Radiation on MHD Free Convective Flow in a Vertical Channel with an Oscillatory Wall Temperature
s2orc_citation_titles
A cat giving birth to puppies?!?
http://pop.wizbangblog.com/2006/11/16/cat-gives-birth-to-puppies.php\n\nCould this really be possible? \n\nI thought dogs and cats had completely incompatible genes/chromosome counts which meant this would be impossible. I mean they're not even closely related species are they?
yahoo_title_question
Spirocyclic Zwitterionic λ5Si-Silicates with Two Bidentate Ligands Derived from α-Amino Acids or α-Hydroxycarboxylic Acids: Synthesis, Structure, and Stereodynamics
A series of zwitterionic λ5Si-silicates with a (2,2,6,6-tetramethylpiperidinio)methyl group and two identical bidentate ligands derived from glycine, (S)-alanine, (S)-phenylalanine, glycolic acid, (S)-lactic acid, (S)-3-phenyllactic acid, or (S)-mandelic acid were synthesized and structurally characterized (solution and solid-state NMR spectroscopy; single-crystal X-ray diffraction). The chiral λ5Si-silicates with ligands derived from optically active α-amino acids or α-hydroxycarboxylic acids were isolated as enantiomerically and diastereomerically pure compounds that undergo a (Λ)/(Δ)-epimerization in solution.
s2orc_title_abstract
It is beautiful. So light and cool for the warm days
I always get a compliment when I wear this top. It is beautiful. So light and cool for the warm days.
amazon_reviews
What is peoples daily life like in ireland?
What do kids in Ireland do in their daily life?
wikianswers
Last nba player coach?
Who was the last player coach to win a NBA Championship?
wikianswers
/* Set the contents of the JMSExpiration field in the message header. Javadoc description supplied by JsJmsMessage interface.
@Override public final void setJmsExpiration(long value) { if (TraceComponent.isAnyTracingEnabled() && tc.isEntryEnabled()) SibTr.entry(this, tc, "setJmsExpiration", Long.valueOf(value)); getHdr2().setField(JsHdr2Access.JMSEXPIRATION_DATA, Long.valueOf(value)); if (TraceComponent.isAnyTracingEnabled() && tc.isEntryEnabled()) SibTr.exit(this, tc, "setJmsExpiration"); }
codesearch
Angle detection device, a motor provided with this angle detection apparatus, a torque sensor, the electric power steering apparatus and an automobile
A suitable angle detector for correcting the error contained in the output angle information multipole angle detector, a motor provided with this angle detection apparatus, a torque sensor, to provide an electric power steering device and an automobile. A generates a digital electric angle information (θed) in multiplier 12 from the analog angle information outputted from the multi-pole optical encoder 11, the electrical angular velocity ωed by differentiating the electrical angle Shitaed first differentiator 30 calculates the relative against performs processing for correcting discontinuities in the time variation of the angular velocity at the first discontinuity correction circuit 31, an electric angular velocity ωedc passed through the first discontinuous correction circuit 31 this electrical angular velocity Omegaed, It performs correction processing for reducing the high frequency noise components by a digital filter 32. .FIELD 5
s2orc_title_abstract
Read it twice, and will probably read it a ...
Read it twice,and will probably read it a third time. Have also sent copies to two of my friends. A "must read" for anyone planning the next phase of their life
amazon_reviews
When do babies eyes change colors?
How old must a baby be before his eyes change colors?
wikianswers
the great divergence brought about great societal changes in what religion
and toleration. In the era known as the Great Divergence, when in the West the Age of Enlightenment and the scientific revolution brought about great societal changes, Christianity was confronted with various forms of skepticism and with certain modern political ideologies such as versions of socialism and liberalism. Events ranged from mere anti-clericalism to violent outbursts against Christianity such as the dechristianisation of France during the French Revolution, the Spanish Civil War and certain Marxist movements, especially the Russian Revolution and the persecution of Christians in the Soviet Union under state atheism. Especially pressing in Europe was the formation of
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how many times was william ray bonner shot in the leg
William Ray Bonner car and eventually managed to force them to stop. Bennett then left his vehicle armed with his shotgun and opened fire at Bonner, who then shot at him in return. When police finally caught up with Bonner, a shootout ensued in which he was hit five times in his legs and lower body. Some officers apparently aimed their fire at Bennett first, mistaking him for the gunman. He was hit twice in the head and shoulders and succumbed to these wounds four days later. Mrs. Felton also suffered minor injuries in the shoulder. At 3:29 p.m. Bonner was taken into
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They are perfect. So many sizes for the price
I wanted these for everyday use. They are perfect. So many sizes for the price! And they don't bother my ears or look cheap. Would definitely buy again as a gift and would recommend to others.
amazon_reviews
who is malar's girlfriend in leelai leelai
that he has also worked on a song for the theatrical trailer. Leelai Leelai () is a 2012 Tamil romantic comedy film directed by Andrew Louis and produced by Ramesh Babu. It stars débutantes Shiv Pandit and Manasi Parekh in lead roles along with Santhanam and Suhasini Raju in pivotal roles. The film which began in May 2008, opened after production delays on 27 April 2012 to positive reviews. The film begins with a trio of friends in college (Malar, Mona, Gayathri). Mona falls in love with Karthik (Shiv Pandit) despite the advice of Malar (Manasi Parekh Gohil) who suspects
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Cholesterol and Cognitive Performance in Normal Controls and the Influence of Elective Statin Use after Conversion to Mild Cognitive Impairment: Results in a Clinical Trial Cohort
Statins and cognition: a systematic review and meta-analysis of short- and long-term cognitive effects.
s2orc_citation_titles
How do you download apps on a nook color?
How do you download online pictures to your nook color?
wikianswers
Who was the maker of Cadbury Chocolate?
When was cadbury chocolate created?
wikianswers
What term is defined as the quality given to a sound by its overstone?
What term is defined as the quality given to a sound by its overtunes?
wikianswers