PMID
int64 35.7M
36.4M
| Title/Abstract
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36,297,095
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associ circul branch chain amino acid tempor risk develop type diabet mellitus systemat review meta analysi recent studi conclud elev circul branch chain amino acid bcaa associ pathogenesi type diabet mellitus tdm obes howev develop associ time quantif strength associ individu bcaa prior tdm diagnosi remain unexplor
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D000597;D003924
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T123;T047;T116
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36,297,094
|
structur character immunomodulatori activ polysaccharid pleurotus abieticola fruit bodi polysaccharid obtain mushroom report possess immunomodulatori properti studi water solubl polysaccharid purifi fruit bodi pleurotus abieticola entitl pap composit structur analysi immunomodulatori activ investig immunosuppress mice induc cyclophosphamid ctx dosag mgkg intraperiton inject day day intragastr administr pap allevi cyclophosphamid ctx induc histopatholog damag increas express splenic cd cd cd igm serum immunosuppress mice pap suppress oxid stress indic prevent increas ros mda level accord intestin microflora analysi pap regul bacteria gene level includ helicobact paraprevotella relat immun oxid capac compar ctx treat mice signific increas immun relat cytokin interleukin il il il serum mice treat pap observ final pap strong increas express nuclear factor erythroid relat factor nrf downstream protein conclus pap boost immun may relat suppress oxid stress via enhanc activ nrf signal thus pap investig candid immunomodulatori therapi
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D048690;D056747;D011134
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T061;T121;T004;T109
|
36,297,093
|
health care profession deliv low carbohydr diet program reduc bodi weight haemoglobin ac diabet medic use cardiovascular risk marker singl arm intervent analysi studi examin effect health care profession deliv low carbohydr diet program diversa health program aim improv obesitytyp diabet manag peopl live australia adult age sd yrs particip januari august day pre post data collect key outcom variabl bodi weight hbac includ analysi averag particip durat day report consult visit bodi weight reduc kg n p lt weight loss kg kg kg respect classif normal weight n overweight n obes n commenc hbac reduc n p lt member commenc hbac lt n n n hbac reduc respect member commenc hbac experienc hbac reduct achiev final hbac lt inclus exclus metformin respect diabet medic prescrib member reduc medic prescrib member final visit health care profession deliv low carbohydr diet program facilit weight loss improv glycaem control greatest improv clinic relev individu wors baselin paramet
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D002318;D003920;D008687;D003924
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T121;T047;T109
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36,297,092
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covid gut injuri covid induc sever acut respiratori syndrom coronavirus sar cov current pandem led million patient million death global male suscept covid infect associ higher chanc develop sever covid femal age peopl high risk covid infect young children also increas case covid patient typic develop respiratori system patholog howev symptom gastrointestin gi tract also common inflammatori cell recruit secret cytokin found gi tract covid patient microbiota chang key featur covid patient gut injuri review current known mechan covid induc gut injuri accept one sar cov bind angiotensin convert enzym ace receptor host cell gi tract interest inflammatori bowel diseas ibd inflammatori disord patient ibd increas risk develop covid current cure covid anti virus monoclon antibodi reduc viral load shorten recoveri time diseas summar current therapeut target symptom gi tract includ probiot ace inhibitor nutrient promis therapeut option covid induc gut injuri
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D000086382;D005767
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T047;T067
|
36,297,091
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genet determin hydroxyvitamin concentr relev public health twin studi suggest consider genet contribut variabl hydroxyvitamin oh concentr report herit estim studi genom wide associ studi gwas suggest notabl lower rate identifi mani independ variant associ serum oh concentr discoveri provid novel insight metabol pathway review outlin find gwas studi date particular focus variant provid replic evid associ oh across independ larg scale analys oh associ variant link direct vitamin metabol pathway other may reflect differ storag capac lipid metabol pathway reflect skin properti construct genet score includ oh associ variant show genet differ oh concentr persist across season odd low concentr lt nmoll halv individu highest vitamin genet score compar lowest quintil impact may notabl influenc retain adequ level also discuss recent studi person approach vitamin supplement show mendelian random studi help inform public health strategi reduc advers health impact vitamin defici
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D055106;D014808
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T063;T047
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36,297,090
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associ omega index hyperglycemia depend bodi mass index among adult unit state inconsist regard associ long chain n polyunsatur fatti acid eicosapentaeno acid epa n docosahexaeno acid dha n risk type diabet present studi aim investig associ omega index erythrocyt epa dha glycem status function bodi mass index bmi cross section data routin clinic laboratori test total peopl age year bmi kgm includ patient hyperglycem fast plasma glucos level mgdl normal weight overweight obes odd ratio or hyperglycem invers associ omega index weaken bmi increas thus or ci compar quintil quintil normal weight group overweight group obes group similar pattern seen epa dha separ present studi suggest low omega index associ greater risk disord glucos metabol independ bmi
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D003924;D015525;D006943
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T123;T121;T109;T033;T047
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36,297,089
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combin use medium short chain fatti acid improv pregnanc outcom sow enhanc ovarian steroidogenesi endometri recept fatti acid play import role maintain ovarian steroidogenesi endometri recept porcin primari ovarian granulosa cell pgcs endometri epitheli cell peec treat without medium short chain fatti acid msfas h mrna abund gene detect fluoresc quantit pcr hormon level pgcs supernat rate adhes porcin trophoblast cell ptrs peec measur sow fed diet without msfas supplement earli gestat fecal vagin microbiom identifi use sequenc reproduct perform record parturit msfas increas mrna abund gene involv steroidogenesi lutein pgcs endometri recept peec p lt estrogen level pgc supernat rate adhes increas p lt dietari supplement msfas increas serum estrogen level total number live piglet per litter p lt moreov msfas reduc fecal trueperella abund vagin escherichia shigella clostridiumsensustricto abund data reveal msfas improv pregnanc outcom sow enhanc ovarian steroidogenesi endometri recept limit abund sever intestin vagin pathogen earli stage pregnanc
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D000821;D011256
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T033;T168
|
36,297,088
|
salt relat knowledg attitud behavior relationship hour urinari sodium excret chines adult salt intak china high increas risk hypertens cardiovascular diseas studi aim assess level salt relat knowledg attitud behavior kab factor influenc explor relationship score salt relat kab h urinari sodium excret collect data individu age year six provinc china face face survey carri focus kab relat salt reduct particip ask collect one h urin sampl particip complet urin collect mean score overal kab sd compos three element knowledg sd attitud sd behavior sd averag h urinari sodium excret sd mmol equival urinari sodium excret sd gd found salt relat knowledg attitud behavior overal kab score invers associ h urinari sodium excret everi one point increas kab score h urinari sodium excret decreas mmol ci also found locat ruralurban sex age educ associ salt relat kab score result suggest larg scale health educ need reduc salt intak chines popul particular effort focus reach live rural area low educ level older peopl
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D006973;D012982
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T168;T047
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36,297,087
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altern healthi eat index incid non communic diseas find year follow women cohort australian longitudin studi women health non communic diseas ncds multimorbid two chronic condit increas global diet risk factor ncds aim investig associ diet qualiti dq incid ncds particip australian longitudin studi women health cohort ncd complet dietari data survey age year respond least one survey survey survey dq measur altern healthi eat index ahei outcom includ coronari heart diseas chd hypertens ht asthma cancer exclud skin cancer diabet mellitus dm depress andor anxieti multimorbid caus mortal repeat cross section multivari logist regress perform investig associ baselin dq ncds year ahei mean sd particip n rang invers associ ahei incid asthma survey q q ci baselin dq predict occurr ncds multimorbid age year well plan larg prospect studi conduct young women need explor dietari risk factor establish ncds
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D000073296;D001249
|
T047
|
36,297,086
|
atp bind cassett transport famili c protein particip synthesi efflux hexosylceramid liver cell addit sphingomyelin ceramid sugar deriv ceramid hexosylceramid hexcer major circul sphingolipid shown silenc abca transmembran protein function instanc case loss function abca gene result low level hdl well concomit reduct plasma hexcer level howev protein involv hepat synthesi egress hexcer cell well known although abca seem indirect control hexcer plasma level support hdl synthesi studi hypothes protein abca involv transport hexcer hdl use unbias knockdown approach found atp bind cassett transport protein c abcc particip synthesi hexcer therebi affect egress hdl human hepatoma huh cell furthermor liver abcc defici mice signific lower level hexcer compar wild type liver studi suggest abcc partak modul synthesi subsequ efflux hexcer hdl liver cell
|
D018528;D002518;D008099
|
T123;T023;T116;T109
|
36,297,085
|
effect whey peptid supplement sarcopen obes high fat diet fed mice incid sarcopen obes gradual increas parallel age popul research examin effect whey peptid wp supplement withwithout resist exercis sarcopen obes male month old cblj mice fed control diet kcal fat high fat diet kcal fat week high fat diet fed mice random divid four group obes control group ob wp wp wpe wp wp supplement mgdaykg bw gavag ladder climb five time week repetit bw load conduct addit week protein mrna level marker relat energi protein lipid metabol analyz skelet muscl adipos tissu one way analysi varianc anova wp supplement regardless signific suppress increas fat mass p decreas lean mass p allevi abnorm morpholog chang skelet muscl adipos tissu p lt adipos tissu wp supplement regardless amelior dysregul energi metabol contribut reduct adipocyt differenti ppar p cebp p skelet muscl wp supplement regardless allevi energi metabol dysregul result regul protein degrad atrogin p murf p apoptosi bax p taken togeth current studi elucid wp supplement regardless potenti anti obes anti sarcopen effect sarcopen obes
|
D059305;D055948
|
T061;T047
|
36,297,084
|
proteom character food deriv bioactiv peptid anti allerg anti inflammatori properti bioactiv peptid found food dietari supplement respons health benefit applic human anim medicin health benefit includ antihypertens antimicrobi antithrombot immunomodulatori opioid antioxid anti allerg anti inflammatori function bioactiv peptid obtain microbi action main gastrointestin microbiota protein present food origin either veget anim matter action differ gastrointestin proteas proteom play import role identif bioactiv peptid high resolut mass spectrometri princip techniqu use detect identifi differ type analyt present complex mixtur even avail low concentr moreov proteom may provid character epitop develop new food allergi vaccin use immunomodul peptid induc oral toler toward offend food allergen even prevent allerg sensit addit food deriv bioactiv peptid investig anti inflammatori properti provid safer altern nonsteroid anti inflammatori drug nsaid bioactiv peptid potenti sourc novel drug ingredi food pharmaceut follow review focus food deriv bioactiv peptid antiallerg anti inflammatori properti summar new insight use proteom identif quantif
|
D018926;D000890;D010455
|
T121;T116
|
36,297,083
|
acquir vitamin b defici newborn posit impact newborn health earli detect earli diagnosi intervent vitamin b defici exclus breastf infant mother low vitamin b crucial prevent possibl irrevers neurolog damag megaloblast anemia failur thrive assess use earli detect asymptomat b defici relat acquir condit highlight import monitor serum vitamin b level pregnanc describ demograph clinic dietari biochem data includ evolut vitamin b defici function biomark enrol newborn male age rang month old exclus breastf asymptomat case refer metabol unit due alter expand newborn screen high level methylmalon acid andor total homocystein thci mother vegetarian diet except three abnorm b absorpt present low borderlin serum b level high plasma level thci supplement oral vitb establish metabol homeostasi mother infant therapi intramuscular inject mg hydroxocobalamin led rapid normal metabol pattern healthi outcom observ acquir b defici rule proceed differenti diagnosi cobalamin metabol deficit methylmalon acidemia homocystinuria
|
D008764;D014806
|
T047;T109
|
36,297,082
|
effect lysophosphatidylcholin intestin health turbot fed high lipid diet week feed trial conduct turbot fed four experiment diet contain differ lpc level name lpc lpc lpc lpc respect intestin morpholog result show widen lamina propria mix inflammatori cell lpc supplement group dietari lpc remark decreas express tlrs tlr tlr tlr tlr myd signal molecul nf b jnk ap similar diet lpc supplement mark depress gene express nf b jnk signal pathway downstream gene tnf il bax caspas caspas furthermor dietari lpc modifi intestin microbi profil increas relat abund short chain fatti acid produc lactic acid bacteria digest enzym produc bacteria predict function intestin microbiota show turbot fed lpc diet relat higher abund function lipid metabol immun system lower abund function metabol diseas immun system diseas activ intestin acid phosphatas alkalin phosphatas also increas dietari lpc conclus lpc supplement could regul intestin mucos barrier via tlr signal pathway alter intestin microbiota profil turbot fed high lipid diet
|
D005412;D008659
|
T047;T013
|
36,297,081
|
singl combin caffein taurin supplement improv athlet cognit perform without affect fatigu level elit boxer doubl blind placebo control studi previous studi effect singl combin intak caffein caf taurin tau exercis perform investig howev potenti synergist effect physic cognit perform fatigu induc anaerob exercis unknown effect singl combin caf tau supplement wingat test elit male boxer evalu balanc agil cognit perform fatigu investig first time studi twenti elit male boxer year old divid four group doubl blind random crossov studi caf mgkg caffein tau g singl dose taurin caf tau co ingest g singl dose taurin mgkg caffein pla mg maltodextrin find follow co ingest caf tau improv peak wkg averag w minimum w power time reach rpe perform compar pla group signific p lt similar determin singl dose tau creat signific differ p lt peak power wkg averag minimum power w valu compar caf group accord balanc agil test perform wingat test co ingest caf tau reveal signific differ p lt compar pla group term cognit perform co ingest caf tau signific improv neutral reaction time ms compar tau caf pla group result elit male boxer perform better term agil balanc cognit function consum combin mgkg caf g tau determin combin use supplement effect singl use
|
D002110;D054874
|
T121;T055;T109
|
36,297,080
|
effect l citrullin supplement endotheli function blood pressur hypertens postmenopaus women age menopaus associ decreas nitric oxid bioavail due reduc l arginin l arg level contribut endotheli dysfunct ed ed preced arteri stiff hypertens develop major risk factor cardiovascular diseas studi investig effect l citrullin l cit endotheli function aortic stiff rest brachial aortic blood pressur bp hypertens postmenopaus women twenti five postmenopaus women random week l cit g placebo pl serum l arg brachial arteri flow mediat dilat fmd aortic stiff carotid femor puls wave veloc cfpwv rest brachial aortic bp assess week l cit supplement increas l arg level vs moll p lt fmd vs p compar pl rest aortic diastol bp vs mmhg p mean arteri pressur vs mmhg p signific decreas week l cit compar pl although statist signific p cfpwv decreas l cit supplement ms find suggest l cit supplement improv endotheli function aortic bp via increas l arg avail
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D006973;D059289
|
T047;T046
|
36,297,079
|
impact higher protein intak patient prolong mechan ventil prolong mechan ventil pmv associ poor outcom high econom cost associ protein intak pmv rare investig previous studi studi aim investig impact protein intak wean mechan ventil patient pmv mechan ventil hday day hospit decemb april includ studi demograph data nutrit record laboratori data wean condit surviv data retriev patient electron medic record total patient elig analysi patient divid two group wean success n wean failur n patient daili protein intak greater gkgday signific shorter median day ventil use less daili protein intak vs day respect p lt daili protein intak gkgday odd ratio p daili protein intak gkgday odd ratio p improv serum albumin odd ratio p bmi odd ratio p independ predictor success wean serum creatinin level th week remain similar patient daili protein intak either gt gkgday gt gkgday p p respect higher protein intak may benefit wean patient pmv negat impact renal function
|
D012121;D015300
|
T061
|
36,297,078
|
develop relat valid reproduc short food frequenc questionnair japanes develop short food frequenc questionnair ffq use assess diet qualiti japan special refer prevent non communic diseas assess rank perform ffq reproduc develop item food group beverag ffq consider japanes dietari cultur evid diseas prevent twenti four univers faculti member particip valid studi complet day photograph food record answer ffq next day last food record time week later time calcul spearman correl coeffici intak food group photograph food record consumpt frequenc ffqs rank abil consumpt frequenc food group ffqs time time reproduc spearman correl coeffici food record ffq time rang median valu compar comparison ffq time energi adjust intak food record correspond valu somewhat weaken mani food group correl coeffici two ffqs rang median short ffq show accept reproduc abil rank consumpt food group
|
D004032
|
T168
|
36,297,077
|
would buy plant base beef patti survey product attribut prefer willing pay among consum liaon provinc china carbon emiss product beef account major carbon emiss anim husbandri anim husbandri turn main driver global carbon emiss present relat studi consum prefer beef substitut especi develop countri howev plant base meat great signific solv tens relationship suppli demand ensur sustain develop improv food safeti improv anim welfar base survey data consum liaon provinc china paper adopt choic experi method studi consum prefer willing pay four type plant base beef patti product attribut traceabl safeti certif brand price use multivari logit mnl model result show consum show greater prefer willing pay plant base beef patti strong traceabl fulli disclos safeti certif inform matur product technolog consum general strong brand prefer differ prefer product attribut addit environment focus consum greater degre prefer traceabl product studi explor micro decis mechan purchas plant base meat product develop countri research conclus paper guid signific busi engag plant base meat product process addit use attribut tag studi also refer signific regulatori standard decis make depart govern invest
|
D008461;D000069466
|
T168
|
36,297,076
|
impact meal dietari inflammatori index exercis induc chang airway inflamm adult asthma research suggest exercis may reduc eosinophil airway inflamm adult asthma dietari inflammatori index dii quantifi inflammatori potenti diet associ asthma outcom studi aim determin whether dii meal consum either exercis influenc exercis induc chang airway inflamm total adult asthma randomis min moder vigor exercis control group particip consum self select meal two hour pre two hour post intervent energi adjust dii e dii tm determin meal meal characteris anti inflammatori pro inflammatori accord median dii induc sputum cell count measur pre four hour post intervent particip consum anti inflammatori meal two hour post exercis decreas sputum eosinophil compar particip consum pro inflammatori meal two hour post exercis p posit correl e dii score post exercis meal chang sputum eosinophil rs p e dii score meal consum two hour pre exercis effect sputum eosinophil p studi suggest anti inflammatori meal two hour post exercis augment exercis induc improv eosinophil airway inflamm adult asthma
|
D001249
|
T047
|
36,297,075
|
comparison effect low carbohydr versus low fat diet type diabet systemat review meta analysi random control trial clinic benefit low carbohydr lc diet compar low fat lf diet peopl type diabet td remain uncertain conduct meta analysi random control trial rcts compar efficaci safeti peopl td rcts compar diet particip td identifi medlin embas cochran librari manual search bibliographi mean differ relat risk cis pool measur glycaemia cardiometabol paramet advers event use follow time point short term month intermedi term month long term month twenti two rcts compris most obes particip td includ month lc vs lf diet signific reduc hbac level mean differ ci lc diet signific reduc bodi weight bmi fast insulin triglycerid increas total cholesterol hdl c level short intermedi term decreas requir antiglycaem medic intermedi long term signific differ paramet advers event except reduc hbac level adipos paramet short intermedi term lc diet appear equal effect lf diet term control cardiometabol marker risk advers event obes patient td
|
D003924;D002318
|
T047
|
36,297,074
|
mediterranean diet western diet adolesc depress current report depress one common mental disord world current grow social health problem grow scale problem concern adult particular affect children adolesc prevent earli diagnosi treatment mood disord adolesc crucial adolesc depress risk factor recurr depress later life well mani mental health disord adulthood purpos studi analyz data dietari pattern composit mediterranean diet modifi risk factor depress would viabl prevent strategi good target earli intervent support treatment depress research show mediterranean diet pattern reduc risk symptom depress western eat style increas risk sever depress adolesc number studi adolesc popul continu increas longitudin clinic studi still insuffici modif diet help strategi prevent treatment depress adolesc therefor diet young peopl consid key modifi goal prevent mental disord
|
D038441
|
T061
|
36,297,073
|
give surgic patient probiot although various hypothes health promot role probiot supplement play via target gut microbiota andor regul system immun metabol respons precis natur benefit restitut health follow surgeri remain discuss doubt
|
D019936;D000069196
|
T007;T001
|
36,297,072
|
uteroplacent insuffici caus microbiota disrupt lung develop impair growth restrict newborn rat preclin studi demonstr intrauterin growth retard iugr associ reduc lung develop neonat period infanc uteroplacent insuffici upi affect approxim human pregnanc common caus iugr studi investig effect upi lung develop intestin microbiota correl newborn rat iugr use bilater uterin arteri ligat induc upi matern fecal sampl collect postnat day postnat day lung intestin microbiota sampl collect left lung lower gastrointestin tract right lung harvest histolog assess western blot analysi result show upi bilater uterin arteri ligat alter matern gut microbiota iugr impair lung develop angiogenesi newborn rat moreov postnat day presenc acinetobact delftia lung acinetobact nevskia gastrointestin tract negat correl lung develop bacteroid lung rodentibact romboutsia gastrointestin tract negat correl lung develop day upi may regul lung develop angiogenesi modul newborn rat intestin lung microbiota
|
D010927;D064307
|
T001;T047;T032;T028
|
36,297,071
|
repli chao et al comment nahok et al monosodium glutam induc chang hepat renal metabol profil gut microbiom wistar rat nutrient sincer appreci thorough review insight dr huichia chao colleagu
|
D012970;D000069196
|
T121;T007;T116;T168;T001
|
36,297,070
|
comment nahok et al monosodium glutam induc chang hepat renal metabol profil gut microbiom wistar rat nutrient letter comment studi nahok k et al
|
D012970;D000069196
|
T121;T007;T116;T168;T001
|
36,297,069
|
ginger root extract improv gi health diabet rat improv intestin integr mitochondri function background emerg research suggest hyperglycemia increas intestin permeabl ginger bioactiv compound report benefit diabet anim due anti inflammatori antioxid properti studi reveal benefici effect gingerol enrich ginger geg intestin health ie barrier function mitochondri function anti inflamm diabet rat method thirti three male spragu dawley rat assign three group low fat diet control group high fat diet hfd streptozotocin singl low dose mgkg bodi weight bw week hfd feed dm group hfd streptozotocin geg diet geg group day glucos toler test gtt insulin toler test itt conduct baselin prior sampl collect total pancreat insulin content determin elisa total rna intestin tissu extract mrna express use qrt pcr result compar dm group geg group improv glucos toler increas pancreat insulin content compar without geg dm group geg supplement geg group increas gene express tight junction claudin antioxid capac sod decreas gene express mitochondri fusion mfn fission fis biogenesi pgc tfam mitophagi lcb p pink inflamm nf b conclus ginger root extract improv glucos homeostasi diabet rat part via improv intestin integr mitochondri dysfunct gi health
|
D020939;D003921
|
T050;T002
|
36,297,068
|
assess select intestin permeabl marker children food allergi depend type sever clinic symptom food allergi fa broad rang symptom clinic manifest may concern sever reaction one system organ
|
D005512;D003876;D005767
|
T047;T046
|
36,297,067
|
combin supplement coenzym q nutrient specif medic condit coenzym q coq compound crucial role mitochondri bioenerget membran antioxid protect despit ubiquit endogen biosynthesi specif medic condit associ low circul coq level howev previous studi oral coq supplement yield inconsist outcom articl review previous coq trial either singl combin nutrient stratifi studi particip accord metabol status medic condit coq supplement trial elder report mani favor outcom howev singl intervent less promis host metabol status worsen likelihood multipl nutrient insuffici patient establish diagnosi metabol immun relat disord contrari mix coq supplement interact nutrient creat promis impact host compromis nutrient reserv furthermor result either singl combin intervent less promis far advanc condit establish damag neurodegen disord cancer limit high level evid studi host metabol categori could conclud consider whether take supplement vari individu metabol status nutrient reserv studi warrant
|
D014451;D000975
|
T123;T121;T109;T039;T044
|
36,297,066
|
young australian adult prefer video post dissemin nutrit inform social media platform instagram pilot cross section survey grow social media use young adult may applic health promot studi aim determin accept feasibl use instagram dissemin nutrit inform young australian assess prefer post style cross section web base pilot survey conduct year old resid new south wale eight set mock instagram post generat compris three format texticon ii realist imag iii video respond n ask review rank post highest lowest accord likelihood engag visual prefer motiv chang eat behavior relev inform friedman test wilcoxon sign rank test post hoc analysi bonferroni correct conduct determin differ three post style video style post like engag p lt visual prefer p lt motiv chang eat behavior p lt present relev food nutrit knowledg p lt compar post style particip report instagram suitabl platform share food nutrit inform find pilot studi use inform larg studi investig use instagram among divers popul greater number video post tailor audienc segment
|
D061108
|
T170
|
36,297,065
|
postprandi glucos gastrointestin hormon respons healthi subject wheat biscuit enrich l arginin branch chain amino acid plant origin studi investig effect wheat biscuit supplement plant flour origin legumesse enrich either l arginin l arg branch chain amino acid bcaa postprandi glucos respons healthi subject gastrointestin hormon amino acid respons well subject appetit sensat also evalu subject consum wheat base biscuit enrich either l arg argb bcaa bcaasb convent wheat biscuit cb glucos solut gs acut random crossov design respons glucos insulin ghrelin glucagon like peptid glp peptid yy pyy glicentin well l arginin l leucin l isoleucin l valin evalu min consumpt argb bcaasb elicit lower glucos iauc compar gs p lt lower iauc insulin observ consumpt bcaasb p lt compar cb argb argb elicit higher iauc glp accompani higher glicentin respons p lt compar cb bcaasb argb increas postprandi amino acid concentr caus stronger satieti effect compar cb increas protein content wheat biscuit supplement plant flour origin legumesse decreas postprandi glycemia provid healthier snack altern easili incorpor diet
|
D005768
|
T125
|
36,297,064
|
mediat role dietari inflammatori index associ eat breakfast obes cross section studi obes close relat diet includ regular meal inflamm diet previous studi focus associ among eat breakfast regard import meal dietari inflamm obes studi analyz data nation health nutrit examin survey nhane particip involv obes dietari inflamm measur bodi mass index bmi dietari inflammatori index dii respect eat breakfast defin two day dietari recal base nhane dietari data pro inflammatori diet skip breakfast posit associ obes whole popul compar eat breakfast recal skip breakfast higher obes especi individu report recal particip diabet sensit popul associ compar particip report breakfast recal mediat proport particip report breakfast one recal recal respect associ eat breakfast obes part mediat dii recommend eat breakfast regular reduc dietari inflamm well obes especi diabet popul
|
D062408;D005247
|
T055;T056;T040
|
36,297,063
|
celiac diseas gallbladd pathophysiolog aspect clinic issu background celiac diseas cd immun mediat disord primarili affect small intestin howev extra intestin organ often affect patholog process regard digest system liver alter cd patient wide describ also extend biliari tract notabl gallbladd function alter cd patient review specif analyz summar main pathophysiolog aspect clinic evid gallbladd dysfunct cd patient order discuss potenti medic complic clinic research gap addit perturb bile composit cd patient develop gallbladd dysmotil main express impair empti digest phase main pathophysiolog determin perturb cholecystokinin secret specif duoden enteroendocrin cell respons appropri nutrient stimul cd patient situat appear revers gluten free diet case despit gallbladd impair cd patient seem predispos gallbladd complic calcul acalcul cholecyst howev clinic studi activ investig clinic aspect may complet evidenc far altern substanti improv last two decad regard cd diagnosi reduc diagnost delay relat dietari treatment may lessen potenti clinic consequ cd relat gallbladd dysfunct specif clinic studi focus aspect need better understand clinic implic gallbladd alter cd patient
|
D002446;D005705
|
T047
|
36,297,062
|
benefit risk earli life iron supplement infant frequent supplement iron prevent iron defici iron supplement may advers effect infant health although iron supplement high effect improv iron status prevent iron defici anemia iron may advers affect growth develop may increas risk certain infect sever review exist area howev none fulli summar report outcom iron supplement infanc review summar risk benefit iron supplement report control studi relev anim model addit discuss mechan may under benefici advers effect
|
D018798;D000090463
|
T047
|
36,297,061
|
give famili voic equit healthi food access wake onlin groceri shop understand view famili low incom background inequ healthi food access groceri purchas critic food access polici studi explor perspect famili elig supplement nutrit assist program snap healthi food access physic onlin groceri environ qualit design use purpos sampl primari household food purchas children age novemb march onlin focus group depth interview ground theori use identifi communiti level perceiv inequ includ influenc covid pandem snap onlin groceri servic salient perceiv caus inequit food access neighborhood resourc defici public transport limit rural communiti peopl disabl older adult racial ethnic divers group perceiv disproportion impact food inequ exacerb pandem abil use snap benefit buy food onlin facilit healthi food access deliveri fee lack control food select barrier barrier healthi food access aggrav snap includ social stigma inabl acquir cook meal inadequ amount month fund find provid foundat polici redesign promot equit healthi food system
|
D000086382;D063105
|
T047;T064;T067;T057
|
36,297,060
|
keton ester supplement improv aspect cognit function simul soccer match induc mental fatigu keton supplement propos enhanc cognit exercis assess whether benefit due reduc cognit fatigu latter portion typic sport game action induc cognit fatigu provid keton monoest supplement kme vs non calor placebo plac assess cognit perform simul soccer match ssm doubl blind balanc crossov design nine recreat activ men cm kg bodi fat vo max mlkg bm min mean sd complet min ssm block intermitt variabl intens exercis consum either kme g plac min mental fatigu task cognit function stroop choic reaction task crt blood metabolit measur throughout match kme reduc concentr blood glucos block vs mm p block vs mm p blood lactat block vs mm p block vs mm p ssm vs plac perhap indic cho spare effect treatment result impair crt perform ssm relat baselin kme display reduc p lt perform decreas compar plac vs reduct correct answer p differ cognit function seen data suggest kme supplement attenu decrement crt repeat high intens intermitt exercis studi warrant assess fulli potenti cognitivephys benefit kme athlet
|
D012916;D054874
|
T055;T056
|
36,297,059
|
associ dietari fatti acid pattern colorect cancer risk larg scale case control studi china associ dietari fatti acid risk colorect cancer crc remain controversi object studi examin whether dietari deriv fatti acid pattern relat crc risk among chines peopl total crc patient frequenc match control interview case control studi juli may food frequenc questionnair use gather inform dietari intak four fatti acid pattern identifi use factor analysi even long chain fatti acid pattern statist signific associ crc risk adjust odd ratio aor confid interv ci p trend howev signific invers associ found medium chain long chain satur fatti acid sfa pattern aor ci high unsatur fatti acid pattern aor ci odd chain fatti acid pattern aor ci crc risk interact fatti acid pattern sex observ associ high unsatur fatti acid pattern crc risk differ subsit conclus increas intak food rich medium chain sfas high unsatur fatti acid odd chain fatti acid may relat lower risk crc
|
D004041;D015179
|
T168;T191
|
36,297,058
|
surgeon know probiot back fuller r work gut flora conclud good evid complex microbi flora present gastrointestin tract effect provid resist diseas howev composit protect flora alter dietari environment influenc make host suscept diseas
|
D019936;D000069196;D066231
|
T097;T007;T001
|
36,297,057
|
analysi socioeconom util matern health servic toddler characterist stunt risk factor stunt preval south kalimantan higher nation figur sixth highest indonesia mani studi south kalimantan analys risk factor stunt comprehens combin sociodemograph factor util matern health servic characterist children therefor purpos studi analys sociodemograph factor util matern health servic characterist children determin stunt south kalimantan provinc studi use analyt observ method cross section design data collect use secondari data result south kalimantan baselin health research total popul toddler obtain south kalimantan baselin health research data toddler taken sampl data analysi use chi squar test bivari test logist regress multivari test relationship mother educ level p father educ p toddler age p lt low birth weight p exclus breastfeed p underweight p stunt data continu logist regress test domin variabl relat stunt underweight p lt five age p lt valu age month prematur birth p conclus studi import factor incid stunt south kalimantan underweight nutrit status
|
D013851;D008427
|
T033;T058
|
36,297,056
|
netrin promot viscer adipos tissu inflamm obes associ insulin resist netrin ntn exhibit pro anti inflammatori role differ set play import role obes associ low grade chronic inflamm aim determin impact ntn obes obes associ type diabet well role viscer adipos tissu vat inflamm total subject enrol case control studi circul level ntn receptor neogenin neo determin weight loss achiev calor restrict bariatr surgeri mrna level ntn neo assess human vat liver peripher blood mononuclear cell vitro studi human viscer adipocyt human monocyt leukemia cell thp deriv macrophag perform analyz impact inflamm relat mediat gene express level ntn receptor neo well effect ntn inflamm increas p lt circul concentr ntn obes decreas p lt diet induc weight loss also associ reduct glucos p lt insulin level p lt gene express level ntn neo upregul p lt vat patient obes highest express stromovascular fraction cell compar matur adipocyt p lt ntn express level enhanc p lt hypoxia inflammatori factor adipocyt macrophag adipocyt condit media strong upregul p lt mrna level ntn macrophag treatment adipocyt ntn promot upregul p lt pro inflammatori chemotact molecul well receptor neo collect find suggest ntn regul vat chronic inflamm insulin resist obes
|
D003924;D007333;D061385;D000075388;D009765
|
T121;T123;T116;T047;T046
|
36,297,055
|
immun system respons kda barley protein mous model studi barley hordeum vulgar l protein taxonom homolog wheat protein react sera patient baker asthma current work crude extract barley protein divid six fraction deae sepharos immunoreact react sera patient confirm food allergi vari kda fraction b frvi show strongest respons silico analysi confirm kda b frvi protein belong trypsinamylas inhibitor famili group mhc type ii allergen next step immunogen b frvi examin mous model shown compar pbs group administr b frvi mice induc almost higher amount specif igg iga earli day immun regardless rout intraperiton oral antigen administr p lt elispot b cell respons confirm stimul mesenter lymphocyt pure b frvi signific increas p lt prolifer lymphocyt group compar cell grow media stimul lyophil beer experi prove strong immunogen kda b frvi protein provid basi futur studi allergen natur protein
|
D001467
|
T168;T002
|
36,297,054
|
determin complementari feed indic secondari analysi thailand multipl indic cluster survey child complementari feed cf practic meet dietari recommend often among educ high incom group much evid associ address inadequ cf address child undernutrit howev mani countri includ thailand child malnutrit assess must address nutrit comprehens data need understand complex situat studi use data thailand multipl indic survey identifi determin cf practic among month children n use newli develop indic logist regress analysi use measur associ sociodemograph factor cf practic fulli adjust model child age primari caregiv educ household incom statist associ appropri cf practic older children age month better minimum dietari divers mdd minimum accept diet mad egg andor flesh food consumpt eff also tend consum unhealthi food proport inappropri cf practic higher among children live caregiv mother matern educ household incom posit associ mdd mad children mother middl class household consum sweeten beverag therefor nutrit program address differ feed problem develop specif differ primari caregiv demograph group
|
D007225;D015362
|
T168;T047
|
36,297,053
|
applic fodmap diet paediatr set adult dietari manag particular fodmap diet key evid base part multimod therapi patient disord gut brain interact particular irrit bowel syndrom review aim describ evid use diet deliv paediatr practic literatur review cover studi fodmap diet adult paediatr set conduct evid efficaci safeti fodmap diet deliv three phase restrict rechalleng personalis consider lack good qualiti clinic trial explor efficaci diet children adolesc likewis limit data safeti concern associ restrict diet paediatr includ impact nutrit growth disord eat behaviour psychosoci famili issu famili gut microbiom evid suggest implement dietari program enhanc skill dietitian navig young person famili healthi eat strategi andor fodmap restrict amelior symptom sinc fodmap diet prescrib global children practic guid clinician use optimis efficaci safeti provid includ less restrict fodmap gentl diet
|
D043183;D010372
|
T047;T091
|
36,297,052
|
anti age neuroprotect properti grifola frondosa hericium erinaceus extract nutrit relev consequ human health increas piec evid indic medicin mushroom sever benefici effect one main issu western countri repres challeng age age relat diseas neurodegen disord among parkinson diseas pd affect million peopl worldwid associ synuclein misfold also found patholog collect call synucleinopathi show aqueous extract two edibl mushroom grifola frondosa hericium erinaceus repres valuabl sourc glucan exert anti age effect yeast benefici effect mediat inhibit raspka pathway increas express heat shock protein along consist increas mean maxim lifespan fungal extract also reduc toxic synuclein heterolog express yeast cell result reduc ros level lower synuclein membran local protein aggreg neuroprotect activ g frondosa extract also confirm pd model drosophila melanogast taken togeth data suggest use g frondosa h erinaceus function food prevent age age relat disord support neuro healthi properti medicin mushroom extract
|
D000363;D000375;D047071;D048691
|
T121;T109;T040;T004;T033
|
36,297,051
|
associ branch chain amino acid intak physic function among chines communiti dwell elder resid studi aim evalu potenti associ dietari bcaa isoleucin leucin valin physic function elder chines popul valid semiquantit food frequenc questionnair anthropometr physic function measur use collect data model trend physic function indic bcaa quartil use multivari linear regress model among men particip age year higher dietari intak bcaa posit associ increas handgrip strength p trend lt shorter time fast walk p trend lt repeat chair rise p trend lt linear associ found subtyp amino acid physic function p trend gt individu highest quartil bcaa intak reduc risk develop low muscl strength multiadjust odd ratio or confid interv cis women men respect similar higher bcaa consumpt associ lower risk develop low physic perform walk speed repeat chair rise higher dietari bcaa intak might benefici physic function elder popul
|
D000597;D057187
|
T123;T056;T116
|
36,297,050
|
mediterranean diet posit impact kidney health pend answer long time question dietari studi conduct chronic kidney diseas ckd patient focus quantiti singl nutrient howev possibl excess attent put restrict protein sodium potassium phosphorus may compromis overal qualiti diet term micronutri palat instead concentr nutrit qualiti healthi dietari pattern may provid better approach improv nutrit prescript ckd patient dietari regimen share common featur reduc content red meat salt satur fatti acid higher fiber content may differ term singl nutrient consumpt particular mediterranean diet med diet associ reduc incid diabet cardiovascular diseas obes condit also strict relat ckd given low content anim protein high content fiber possibl med diet may exert also posit effect ckd well metabol complic review summar role med diet primari prevent ckd progress
|
D038441;D051436
|
T061;T047
|
36,297,049
|
statin induc geranylgeranyl pyrophosph deplet promot ferroptosi relat senesc adipos tissu statin treatment accept prevent advers cardiovascular event howev atorvastatin hmg coa reductas inhibitor report exhibit distinct effect senesc phenotyp whether atorvastatin induc adipos tissu senesc mechan involv unknown effect atorvastatin induc senesc examin mous adipos tissu explant show statin initi higher level mrna relat cellular senesc marker senesc associ secretori phenotyp sasp well increas accumul senesc associ galactosidas sa gal stain adipos tissu furthermor found level reactiv oxygen speci ros malondialdehyd mda fe elev adipos tissu treat atorvastatin accompani decreas express glutathion gsh glutathion peroxidas gpx indic iron depend ferroptosi atorvastatin induc prevent select ferroptosi inhibitor fer moreov supplement geranylgeranyl pyrophosph ggpp metabol intermedi revers atorvastatin induc senesc sasp lipid peroxid adipos tissu explant atorvastatin deplet ggpp product fer atorvastatin abl induc ferroptosi adipos tissu due increas ros increas cellular senesc moreov effect could revers supplement ggpp taken togeth result suggest induct ferroptosi contribut statin induc cell senesc adipos tissu
|
D019161;D000079403
|
T121;T043;T109
|
36,297,048
|
impact famili base assess intervent healthi lifestyl programm health knowledg belief children obes famili determin impact famili base assess intervent healthi lifestyl programm health knowledg belief children famili affect obes second compar health knowledg programm cohort nation cohort aotearoanew zealand nz
|
D063766
|
T033;T047
|
36,297,047
|
recent studi protect effect walnut neuroinflamm neuroinflamm play signific role age process pathophysiolog neurodegen diseas alzheim diseas accord possibl therapeut strategi aim anti inflammatori effect may benefici brain health walnut kernel contain larg quantiti unsatur fatti acid peptid phenol compound anti inflammatori effect long term intak walnut found improv cognit function memori rat human howev modulatori effect walnut neuroinflamm receiv much less attent review focus potenti influenc main regul mechan walnut activ ingredi neuroinflamm includ regul microglia activ induc amyloid lipopolysaccharid inhibit peripher inflamm mediat macrophag reduct oxid stress decreas free radic level boost antioxid defens control gut microb maintain homeostasi howev major evid benefici effect walnut compon neuroinflamm neurodegener come experiment work wherea evid clinic studi benefici effect scarcer less conclus review aim provid new insight neuroinflamm regul mechan natur activ ingredi walnut develop walnut base function food allevi neurodegen diseas
|
D031324;D000090862;D009754
|
T033;T168;T047;T002
|
36,297,046
|
kelulut honey improv folliculogenesi steroidogen aromatas enzym profil ovarian histomorpholog letrozol induc polycyst ovari syndrom rat polycyst ovari syndrom pcos link aberr folliculogenesi abnorm aromatas enzym cypa steroidogen enzym alpha hydroxylas cypa express demonstr kelulut honey kh improv femal male reproduct system anomali anim studi examin effect isol combin kh metformin clomiphen improv folliculogenesi aromatas steroidogen enzym profil ovarian histomorpholog letrozol induc pcos rat letrozol mgkgday administ femal spragu dawley sd rat day induc pcos pcos rat subsequ divid six experiment group untreat treatment metformin mgkgday clomiphen mgkgday kh gkgday combin kh gkgday metformin mgkgday combin kh gkgday clomiphen mgkgday treatment given oral day found kh compar clomiphen metformin improv express cypa cypa apart enhanc folliculogenesi histolog express folliculogenesi relat gene besid combin kh clomiphen effect treatment improv ovarian histomorpholog pcos rat effect kh restor alter folliculogenesi steroidogen aromatas enzym profil pcos warrant futur clinic trial valid therapeut effect clinic
|
D006722;D011085
|
T168;T047
|
36,297,045
|
associ four dietari pattern risk periodont diseas systemat review meta analysi sever dietari pattern report risk factor sever chronic diseas includ oral diseas howev thus far comprehens quantit analysi nutrit periodont diseas
|
D005502;D010510
|
T168;T047
|
36,297,044
|
italian ketogen mediterranean diet overweight obes patient prediabet type diabet obes multifactori diseas strong associ insulin resist andor type diabet mellitus correct nutrit repres valid strategi fight dysmetabol patholog respons numer diseas includ inflammatori cardiovascular one medic nutrit therapi includ mediterranean diet md low calori ketogen diet vlkcd first line treatment prediabetesdiabet overweightobes eighti patient forti women forti men affect overweightobes type diabet mellitus impair glucos toler impair fast glucos ys bmi kgm hac enrol univers servic diet therapi diabetolog metabol diseas policlinico riuniti hospit foggia subject low calori mediterranean diet low calori ketogen mediterranean diet thirti day diet result mark decreas bodi weight kg bmi kgm time low calori ketogen mediterranean diet reduc waist hip circumfer diet help reduc fat mass major loss achiev low calori ketogen mediterranean diet among gluco metabol paramet low calori ketogen mediterranean diet group show signific decreas fast blood glucos hbac insulin c peptid total cholesterol ldl triglycerid result studi seem show low calori ketogen mediterranean diet good strategi improv rapid metabol anthropometr bodi composit paramet patient prediabet diabet overweightobes
|
D055423;D038441;D011236;D003924
|
T061;T047
|
36,297,043
|
associ matern sugar sweeten beverag consumpt infanttoddl ad sugar intak intak ad sugar earli life associ poor health outcom matern dietari intak influenc intak children littl research investig relationship matern sugar sweeten beverag ssb infanttoddl ad sugar intak object explor relationship matern total sugar ssb intak infanttoddl ad sugar intak cross section studi n mother infant dyad measur matern dietari intak food frequenc questionnair infant intak three h dietari recal pearson correl explor relat matern total sugar ssb intak infant ad sugar intak hierarch stepwis regress determin matern total sugar ssb intak explain variat infant ad sugar intak account known risk factor earli introduct ad sugar matern total sugar r p ssb r p lt intak posit correl infanttoddl ad sugar intak hierarch model matern total sugar intak account varianc infant ad sugar intak p matern ssb intak signific contributor infant ad sugar intak p account confound intervent reduc matern ssb consumpt may help reduc infanttoddl ad sugar intak
|
D000080845
|
T168
|
36,297,042
|
vitamin supplement characterist mastic parent supervis toothbrush crucial factor prevent cari month old children sever earli childhood cari ecc defin sign smooth surfac cari child younger three year age remain serious health issu aim studi indic oral health behaviour relat ecc studi survey parent socio econom medic factor oral health behaviour clinic examin children includ non cavit dcavit lesion ecc cari indic mft mfs calcul spearman correl simpl multipl logist regress use assess relationship various factor ecc total children examin ecc occur mft mfs ecc correl socio econom factor vitamin supplement breastfeed use formula th month toothbrush supplement vitamin toothbrush tend decreas odd ecc p p respect feed exclus formula observ increas odd ecc p consum gt three snack daili p reluct eat resili food p nullifi confound factor vitamin supplement mastic resili food breastfeed first six month babi life parent supervis toothbrush factor prevent cari toddler breast bottl feed th month life reluct eat solid lack vitamin supplement hygien neglect delay introduc oral health behaviour may contribut develop cari toddler
|
D014099;D003731
|
T061;T047;T033
|
36,297,041
|
identif factor necessari enabl technolog base dietari record survey qualit focus group interview japanes dietitian weigh food record togeth person interview approach constitut basic method use estim energi nutrient intak dietari survey background coronavirus diseas pandem need non face face dietari survey use inform communic technolog ict increas aim evalu ict base dietari record survey identifi factor may enabl survey method becom wide use futur conduct non face face survey dietari record japanes individu maintain dietitian use dietari photographi video conferenc servic conduct focus group interview six dietitian conduct survey opinion factor necessari popular ict base dietari survey method analyz focus group interview dietitian highlight fewer restrict time place posit aspect negat aspect includ insuffici skill oper comput difficulti hear understand facial express use ict identifi three main factor enabl widespread use ict base dietari record survey individu skill devic technolog social environment factor suggest comprehens approach necessari popular use ict dietari survey
|
D064686;D000086382
|
T047;T067;T097
|
36,297,040
|
time dietari energi nutrient intak bodi mass index children composit data analysi childhood obes project chop trial meal time suggest influenc obes risk children aim analys effect energi nutrient distribut eat occas eo includ breakfast lunch supper snack bmi z score zbmi childhood healthi children bmi three day dietari protocol obtain year age dietari data analys percentag mean total energi intak tei e intak eo transform via isometr log ratio transform ad exposur variabl linear mix effect model stratifi analys countri recategor eo ad intak snack respect meal analys perform exclus subject less three observ exclus subject skip one eo consum energi less one eo examin sensit analys around children overweight given time point overweight normal weight children show differ distribut dietari intak day overweight children consum higher intak lunch lower intak snack howev signific effect time eo zbmi found regress analys
|
D050177;D063766
|
T033;T047
|
36,297,039
|
associ age fertil problem modifi diet qualiti find nation studi reproduct age women australia increas age strong risk factor infertil accumul evid import healthier diet fertil whether healthier diet modifi associ increas age infertil investig studi aim examin better diet qualiti could help reduc age relat infertil ii assess whether chang diet qualiti time associ fertil problem
|
D007247
|
T033;T047;T046
|
36,297,038
|
effect taraxaci herba bone loss ovx induc model regul osteoclast differenti bone dynam tissu maintain homeostasi balanc osteoclast bone resorpt osteoblast bone format women defici estrogen menopaus promot bone resorpt due excess activ osteoclast lead osteoporosi th also known dandelion nativ warm region tradit use treat gynecolog diseas inflamm menopaus major caus osteoporosi caus abnorm activ osteoclast various studi shown anti inflammatori drug potenti treat osteoporosi analyz effect th osteoclast differenti relev mechan use rankl administr th menopaus like rat model ovariectomi rat carri chang bone microstructur analyz via micro ct antiosteoporosi effect th verifi histolog analysi addit pharmacolog effect th anim model osteoporosi compar analyz osteoporosi medic estradiol e alendron aln th signific inhibit initi osteoclast differenti via nfatcc fos mechan addit bone densiti femur osteoporot rat increas express osteoclast relat factor serum tissu control result studi provid object evid inhibitori effect th osteoclastogenesi ovx induc bone loss
|
D001862;D010024
|
T047;T042
|
36,297,037
|
vitamin central nervous system causat prevent mechan brain disord twenti last one hundr year vitamin research involv investig brain target organ hormon group one first investig brain outcom result primarili restrict dietari vitamin brain develop advent new molecular neurochem techniqu neurosci increas interest potenti neuroprotect action vitamin respons varieti advers exposur hormon could affect brain develop function rather provid exhaust summari data list neurolog psychiatr condit vitamin defici associ provid updat action vitamin brain cellular process vitamin may target psychiatri neurolog
|
D014808;D001927
|
T047
|
36,297,036
|
effect p synephrin fat oxid rate exercis increas intens healthi activ women p synephrin princip alkaloid bitter orang citrus aurantium sever recent investig found intak mgkg p synephrin rais fat oxid rate exercis low moder intens howev investig carri sampl male particip mix menwomen sampl therefor aim investig studi effect p synephrin intak fat oxid exercis increas intens healthi women use doubl blind random experi healthi recreat activ women perform two ident exercis trial ingest mgkg p synephrin b mgkg placebo cellulos exercis trial consist ramp test maxim oxygen uptak vo max cycl ergomet substrat oxid rate measur workload indirect calorimetri comparison placebo intak p synephrin increas rest tympan temperatur vs c p effect rest heart rate p systol p diastol blood pressur p exercis signific effect p synephrin fat oxid rate f p carbohydr oxid rate f p energi expenditur rate f p heart rate f p particip perceiv exert f p maxim rate fat oxid placebo gmin similar p synephrin gmin p acut intak mgkg p synephrin exercis modifi energi expenditur substrat oxid submaxim aerob exercis healthi activ women like increas rest tympan temperatur induc p synephrin hinder effect substanc fat util exercis healthi activ women
|
D002957;D013578
|
T168;T121;T002;T109
|
36,297,035
|
high fat diet femal fertil across lifespan compar lesson mammal model femal reproduct focus main achiev fulli grown follicl compet oocyt success fertil well nourish develop offspr pregnanc occur current evid demonstr obes andor high fat diet regim perturb process lead femal infertil transgener disord sinc mechan reproduct process involv yet fulli clarifi present review design systemat compar survey avail literatur avail data demonstr advers influenc obes divers reproduct process folliculogenesi oogenesi embryo developmentimpl negat reproduct impact may attribut direct action reproduct somat germin compart andor indirect influenc mediat endocrin metabol immun axi control system overal present review highlight fragment current inform limit comprehens reproduct impact high fat diet base incid preval obes western countri topic becom research challeng increas self awar dietari reproduct risk propos solid rigor prevent dietari regim well develop target pharmacolog intervent
|
D059305;D008136
|
T061;T102;T079
|
36,297,034
|
preval vitamin calcium defici insuffici women childbear age associ risk factor systemat review meta analysi vitamin defici insuffici well low serum calcium level trigger negat health outcom women childbear age therefor aim estim preval serum vitamin calcium defici insuffici associ risk factor brazilian women childbear age assess whether differ preval accord region countri presenc absenc pregnanc systemat literatur review perform use follow databas pubm lilac embas scopus web scienc cross section cohort intervent studi includ among pregnant women preval vitamin defici rang vitamin insuffici among non pregnant women preval vitamin defici rang vitamin insuffici found high preval vitamin defici insuffici women childbear age insuffici affect half women highest preval vitamin defici insuffici observ south region possibl assess preval factor associ calcium defici
|
D014808;D044342;D002128;D010279
|
T047
|
36,297,033
|
effect altern high sucros sucros free diet intermitt one day fast estrous cycl sex hormon femal rat relationship diet sex hormon concentr estrous cycl import perspect infertil estrogen depend diseas prevent treatment four dietari intervent reflect modern eat behavior explor studi involv femal rat divid five feed group impact amount sucros consum dietari energi content altern high sucros sucros free diet high sucros diet combin intermitt one day fast estrous cycl sex hormon concentr femal rat assess even low amount dietari sucros dietari energi content found lead increas estradiol e concentr decreas progesteron pg concentr high sucros diet even period appli addit led reduc concentr lutein hormon lh largest chang hormon test observ one day fast coupl high sucros diet addit estrous phase shorten estrous cycl disrupt result studi show amount dietari sucros also uptak pattern affect estrous cycl sex hormon concentr femal rat
|
D011374;D005215
|
T123;T121;T109;T055;T033;T125
|
36,297,032
|
trend ultraprocess product intak associ doubl burden malnutrit mexican children adolesc ultraprocess product upp associ unfavor health outcom howev associ coexist undernutrit overnutrit known doubl burden malnutrit dbm individu level
|
D044342;D000740
|
T047
|
36,297,031
|
lotus nelumbo nucifera gaertn leaf ferment supernat inhibit adipogenesi l preadipocyt suppress obes high fat diet induc obes rat lotus nelumbo nucifera gaertn leaf typic homolog ingredi medicin food lipid lower weight loss effect present studi lotus leav ferment two probiot enterococcus faecium wefa enterococcus hira wehi anti adipogen effect enterococcus ferment lotus leaf supernat flls evalu l preadipocyt aim explor whether anti obes abil enhanc ferment enterococcus dig potenti correspond mechan flls ferment e hira wehi flls wehi select investig abil inhibit obes vivo high fat diet hfd induc obes rat male g week old due superior inhibitori effect adipogenesi lipid accumul inhibit rate l cell p wehi l p lt wehi h found oral administr low high dose flls wehi could achiev effect name decreas bodi weight p lt epididym fat mass adipocyt cell size ldl c level p respect liver tc level p lt p respect tg level p p respect fast blood glucos p p improv insulin resist p respect rat model group moreov administr high low dose flls wehi decreas transcript level adipogen transcript factor correspond gene ppar p lt cebp p lt acc p lt fas p lt least three time result indic flls wehi potenti develop healthi anti obes foodstuff
|
D019440;D031653;D009765
|
T121;T047;T002
|
36,297,030
|
wearabl camera reveal larg intra individu variabl time eat among young adult studi shown young adult follow less structur eat pattern compar older cohort may implic dietari assess method reli memori structur meal pattern aim describ intra individu variat eat time young adult age year particip n wore autograph camera captur first person perspect imag everi three consecut day imag timestamp show food consumpt use extract data time first last eat occas eo number eo per day length eat window intra individu variabl calcul data use composit phase deviat cpd coeffici variat cv number individu high high variabl time first last eo respect cpd gt number eo eat window respect cv gt sampl young adult lack regular eat pattern consid select dietari assess method
|
D005247;D000076251
|
T055;T040;T073
|
36,297,029
|
effect spirulina supplement immun cell paramet elit colleg athlet identifi effect spirulina supplement immun cell indic young soccer player prepar period tournament
|
D012916;D053545
|
T056;T007
|
36,297,028
|
chang nutrit status hospit prognosi patient heart failur preserv eject fraction impact chang nutrit status hospit prognosi patient heart failur preserv eject fraction hfpef remain unknown examin associ chang geriatr nutrit risk index gnri prognosi hospit patient hfpef stratifi nutrit status admiss nutrit status worsen patient high gnri admiss patient low gnri admiss respect kaplan meier analysi reveal differ risk composit endpoint caus death heart failur admiss patient high gnri admiss whose nutrit status worsen contrast patient low gnri admiss whose nutrit status worsen signific lower risk composit endpoint caus death multivari analysi reveal worsen nutrit status independ associ higher risk composit endpoint caus mortal patient low gnri admiss chang nutrit status hospit thus associ prognosi patient malnutrit admiss patient without malnutrit among hfpef
|
D006333;D044342
|
T047;T046
|
36,297,027
|
effect curcumin attenu liver cirrhosi via genesprotein pathway system pharmacolog studi liver cirrhosi life threaten seqsuel mani chronic liver disord vari etiolog studi investig protein target curcumin liver cirrhosi base bioinformat approach
|
D003474;D019098
|
T121;T116;T109;T126;T130
|
36,297,026
|
use hierarchi evid appli lifestyl medicin healm approach assess strength evid associ dietari pattern caus mortal dietari guidelin underpin high qualiti evid qualiti assess method reflect tradit evid hierarchi prioritis evid randomis control trial rcts hierarchi evid appli lifestyl medicin healm approach altern qualiti assess method research question practic andor ethic reason answer use rcts aim studi investig healm approach could use assess strength evid associ dietari pattern caus mortal research question difficult answer use rcts two data sourc use exist systemat review dietari pattern caus mortal synthesis evid observ studi overview review conduct summaris relev evid mechanist intervent studi set four criteria develop use applic healm use differ dataset combin strength evid rate grade b moderatesuggest grade c insufficientinconclus healm novel approach integr assess strength evid mechanist intervent observ studi research need address practic challeng identifi applic healm
|
D008019;D018673;D004032
|
T168;T047;T170;T054
|
36,297,025
|
australian feed infant toddler studi ozfit highlight futur direct australian feed infant toddler studi ozfit first nationwid survey feed practic children year key find near half infant exclus breastf month breastfeed durat long infant breastf month breastf second year infant introduc complementari food appropri time month found mismatch number recommend serv food group australian dietari guidelin dietari intak toddler studi toddler consum twice mani fruit serv recommend near consum discretionari food despit allow food toddler consum recommend dairi serv consum half recommend serv food group meat altern grain veget model inform australian dietari guidelin includ allow breastmilk need address quarter toddler ozfit receiv energi breastmilk infant toddler met requir nutrient one except iron older infant toddler inadequ intak excess sodium intak also concern toddler exceed upper limit mgday discuss addit find studi limit gap evid base futur direct
|
D004032;D012982
|
T168
|
36,297,024
|
associ dietari pattern pregnanc gestat hypertens born shenyang cohort studi literatur matern dietari pattern gestat hypertens gh risk larg ambigu investig associ matern dietari pattern gh risk among pregnant women chines pre birth cohort use three day food diari tfd food frequenc questionnair ffq assess diet pregnant women princip compon analysi varimax rotat use identifi dietari pattern tfd ffq respect total particip diagnos gh matern adher wheaten food coars cereal pattern tfd associ lower risk gh quartil q vs q odd ratio ci matern adher sweet food seafood pattern tfd associ lower systol blood pressur q vs q ci mean arteri pressur q vs q ci protect associ sweet food seafood tfd fish seafood pattern ffq risk gh pronounc among women overweightobes pregnanc p interact lt find may help develop intervent better identifi target popul hypertens prevent pregnanc
|
D046110
|
T047;T046
|
36,297,023
|
galectin present breast milk role earli life develop galectin gal famili conserv solubl protein high affin galactosid structur recogn import protein success pregnanc howev littl known presenc breast milk role earli infanc gal concentr evalu multiplex immunoassay mother infant pair mami cohort matern plasma mp n umbil cord plasma ucp n birth breast milk sampl n day postpartum data regard mother infant characterist collect gal present lower concentr rang gal gal plasma specif ucp major find current studi gal detect first time transit breast milk sampl differ found compar two breastfeed time point final gal level associ matern infant characterist gestat age pregnanc weight gain matern diet gender infant growth infant infect conclus gal level seem involv certain development aspect earli life
|
D001942;D037161;D008895
|
T123;T116;T055;T040;T058;T031
|
36,297,022
|
astragalosid supplement enhanc intrins muscl repair capac follow eccentr exercis induc injuri astragalosid shown enhanc endur exercis capac vivo promot muscular hypertrophi vitro howev remain unknown whether astragalosid supplement alter inflammatori respons enhanc muscl recoveri damag human therefor aim evalu effect astragalosid supplement muscl intrins capac regener repair exercis induc damag use random doubl blind placebo control cross design eleven male particip underw day astragalosid supplement total contain mg astragalosid per day placebo control follow eccentr exercis protocol serum blood sampl variabl relat muscl function collect prior immedi follow muscl damag protocol also h day recoveri period assess pro inflammatori cytokin respons secret muscl regen factor muscular strength astragalosid supplement reduc biomark skelet muscl damag serum ck ldh mb compar placebo day follow muscl damag protocol astragalosid supplement suppress secret il tnf whilst increas releas igf initi stage muscl recoveri furthermor follow astragalosid supplement muscular strength return baselin day earlier placebo astragalosid supplement shorten durat inflamm enhanc regener process restor muscl strength follow eccentr exercis induc injuri
|
D018482;D015444;D014315;D012503
|
T061;T024;T109;T056;T023
|
36,297,021
|
evalu prognost capac novel surviv marker patient sinonas squamous cell carcinoma sinonas squamous cell carcinoma snscc malign tumor associ poor surviv easili obtain prognost marker high interest therefor aim assess prognost valu novel surviv index si combin prognost valu clinic n classif invas across ohngren line inflammatori neutrophil lymphocyt ratio nutrit albumin bodi mass index marker patient primarili treat snscc n includ six si compon stratifi low high risk categori subsequ cohort stratifi low si high risk si group si overal surviv os diseas free surviv dfs compar patient low high risk si log rank test use test statist signific overal mortal rate n recurr rate n observ signific better os patient low risk si n mean os year confid interv ci year high risk si n mean os year ci year p moreov also show patient low risk si longer dfs patient high risk si mean dfs ci vs mean dfs year ci p si combin prognost capac well establish clinic radiolog inflammatori nutrit prognost show prognost potenti cohort snscc patient
|
D006258
|
T191
|
36,297,020
|
capsaicin amelior high fat diet induc atherosclerosi apo mice via remodel gut microbiota capsaicin pungent alkaloid abund present pepper outstand biolog activ includ anti atherosclerosi effect previous studi reveal gut microbiota play import role benefici effect capsaicin whether essenti anti atherosclerosi effect capsaicin unclear studi evalu anti atherosclerosi effect capsaicin apo mice explor role deplet gut microbiota improv atherosclerosi result show capsaicin administr could prevent develop atherosclerosi improv serum lipid inflamm antibiot intervent abolish allevi atherosclerosi capsaicin addit capsaicin administr could signific increas abund turicibact odoribact ileibacterium fece decreas abund deoxychol acid cholic acid hypoxanthin stercobilin cecal content studi provid evid gut microbiota play critic role anti atherosclerosi effect capsaicin
|
D050197;D002211;D000069196
|
T121;T007;T109;T047;T046;T001
|
36,297,019
|
allerg disord risk anemia japanes children find japan environ children studi previous epidemiolog studi report increas risk anemia peopl allerg disord howev previous studi follow cross section design aim studi investig associ two condit cohort dataset use data children japan environ children studi largest birth cohort japan associ anemia allerg disord evalu logist regress model propens score analysi adjust potenti confound children asthma odd ratio confid interv ci atop dermat ci allerg rhiniti ci allerg rhinoconjunct ci food allergi ci year age predict high odd develop anemia next year allergi year age associ increas risk anemia age year ci find remain stabl propens score analysi result suggest allerg diseas relat caregiv report anemia children
|
D003876;D065631;D000740
|
T047
|
36,297,018
|
system map new zealand free healthi school lunch programm perspect lunch provid part covid econom recoveri packag aotearoa new zealand govern roll univers free healthi lunch programm least advantag school nationwid studi explor experi school lunch provid hawk bay region aim creat system map identifi point intervent lunch programm could improv meet goal reduc child food insecur twelv lunch provid interview generat casual loop diagram examin integr form singl system map seven theme aros analysi teacher support princip support nutrit guidelin govern support suppli chain ingredi supplier student feedback food wast teacher support import get student tri new food eat nutriti lunch princip support strong theme impact opportun broader student engag studi employ system scienc highlight import support differ stakehold within lunch programm achiev goal reduc child food insecur work need ensur programm meet wider goal govern communiti determin potenti broader benefit programm
|
D005522;D000086382;D012037
|
T047;T095;T067;T057
|
36,297,017
|
diet qualiti level nutrit knowledg among young peopl orthorex tendenc aim studi determin level nutrit knowledg diet qualiti understood term healthi unhealthi eat habit among young peopl orthorex tendenc particip school student univers student employ lublin region n data collect mean questionnair particip ask provid socio demograph data fill orto questionnair dietari habit nutrit belief questionnair kompan particip obtain result rang sd non healthi diet index pro healthi diet index sd domain nutrit knowledg sd varianc analysi show signific differ pro healthi diet index level nutrit knowledg group orthorexia obtain statist higher result pro healthi diet index tendenc toward orthorexia obtain statist higher result non healthi diet index varianc analysi show level nutrit knowledg focus healthi food signific lower group result orto questionnair correl negat pro healthi diet index level nutrit knowledg posit non healthi diet index conclud orthorex group group tendenc toward orthorexia could character moder intens healthi diet low intens non healthi diet level nutrit knowledg orthorex group signific differ group
|
D001068
|
T047;T048
|
36,297,016
|
eat pattern dietari intervent adhd narrat review attent deficit hyperact disord adhd one common neurodevelopment disord childhood affect children adolesc given advers health outcom high healthcar societ cost treatment option beyond pharmacotherapi explor case control studi shown dietari pattern may influenc risk adhd specif dietari intervent propos coadjuv treatment disord includ nutrit supplement gut microbiom target intervent biotic elimin diet purpos review examin dietari pattern associ adhd summar exist evid clinic use dietari intervent literatur show non healthi dietari pattern posit associ adhd wherea healthi pattern negat associ nutrit supplement vitamin vitamin magnesium appear improv adhd symptom baselin level vitamin insufficientdefici regard biotic evid found lactobacillus rhamnosus gg multi speci probiot supplement elimin diet scarc evid lead nutrit defici caution advis overal robust scientif evid requir dietari intervent implement part adhd therapi
|
D001289
|
T048
|
36,297,015
|
whole exom sequenc studi identifi novel rare risk variant habitu coffe consumpt involv olfactori receptor hyperphagia habitu coffe consumpt addict behavior unknown genet variat rais public health issu potenti health relat outcom perform exom wide associ studi identifi rare risk variant contribut habitu coffe consumpt util newli releas uk biobank exom dataset n total qualifi variant import skat conduct gene base burden robust test minor allel frequenc lt adjust polygen risk score prs coffe intak exclud effect common coffe relat polygen risk gene base burden robust test exon variant found seven exom wide signific associ org pskat pskat robust vezt pskat pskat robust irgc pskat pskat robust candid gene verifi gwas summari data coffe intak rs p org rs p irgc studi could help extend genet insight pathogenesi coffe addict may point molecular mechan under health effect habitu coffe consumpt
|
D003069;D018035
|
T168;T116;T192
|
36,297,014
|
branch chain amino acid supplement acceler recoveri chang direct sprint exercis protocol bcaa supplement wide use post exercis recoveri howev evid current avail answer question whether bcaa supplement attenu muscl damag amelior recoveri bout chang direct cod sprint exercis motion frequent use team sport action studi aim assess effect bcaa supplement muscl damag marker subject muscl sore neuromuscular perform vascular health collegi basketbal player h recoveri period standard cod protocol particip oral receiv either bcaa gkg bcaa gkg glucos placebo gkg glucos supplement immedi cod exercis protocol random crossov doubl blind placebo control manner creatin kinas increas immedi exercis peak h muscl sore remain elev h whilst arteri stiff decreas exercis supplement condit neglig lower level interleukin found bcaa supplement condit conclus result studi support benefit bcaa supplement mitig muscl damag sore neuromuscular perform arteri stiff cod basketbal player
|
D000597;D063806
|
T123;T116;T184
|
36,297,013
|
vitamin e cancer treatment review clinic applic random control trial vitamin e along vitamin micronutri play rang physiolog role homeostasi bodi moreov also postul therapeut role often incomplet studi understood scope review explor recent random control trial rcts vitamin e context cancer investig whether vitamin e therapeut role search major bibliograph electron databas identifi sixteen rcts studi role vitamin e cancer manag publish last ten year studi differ methodolog qualiti includ use vitamin e combin treatment furthermor due heterogen result difficult make consensus statement effect vitamin e cancer therapeut case even suggest detriment vitamin e supplement therefor well design larg prospect rcts need studi pure isoform vitamin e establish safeti efficaci dietari supplement
|
D009369;D014810
|
T121;T191;T127;T109
|
36,297,012
|
crosstalk gut microbiota composit clinic cours allerg rhiniti use probiot prebiot bacteri lysat treatment allerg rhiniti although massiv progress discov allerg rhiniti ar aetiolog made recent year preval still rise signific impact patient live non convent research elucid role new factor ar pathogenesi need facilit discoveri new treatment approach one factor gut microbiota specif role health diseas review present process gut microbiota develop especi earli life focus impact immun system emphas link gut microbiota composit immun chang involv ar develop specif elucid signific link bacteria colon gut thth imbal probiot prebiot bacteri lysat medic restor composit intestin bacteria indirect affect clinic cours ar also discuss
|
D000069196;D019936;D065631
|
T047;T007;T001
|
36,297,011
|
unhealthi food choic among healthcar shift worker cross section studi shift healthcar worker group particular expos increas risk poor eat habit affect mani diseas aim studi evalu dietari pattern dps includ polish adapt mediterranean diet polish ame score dietari fat intak associ shift work healthcar worker cross section studi involv healthcar worker west pomeranian poland dietari data collect use ffq posteriori dps deriv princip compon analysi pca polish ame score individu percentag energi dietari fat pfat calcul healthcar shift work compar daili work associ approxim time higher odd adher meatfatsalcoholfish dp upper tertil cl p lt higher pfat gt total energi intak cl p lt healthcar shift work compar daili work associ approxim lower odd adher pro healthi dp middl tertil cl p lt higher level polish ame score cl p lt well lower odd constant mealtim cl p lt obtain find highlight unhealthi food choic among shift healthcar worker thus avoid negat health consequ need nutrit educ healthcar worker especi work shift
|
D005247;D038441
|
T061;T055;T040
|
36,297,010
|
coq resveratrol effect amelior age relat mitochondri dysfunct mitochondria particip mainten cellular homeostasi first mitochondria regul energi metabol oxid phosphoryl addit involv cell fate decis activ apoptot intrins pathway final work intracellular signal hub result tight regul ion metabolit concentr critic signal molecul ros age multifactori process trigger impair differ cellular compon among various molecular pathway involv mitochondria key regul longev inde mitochondri deterior critic signatur age process scenario focus specif age relat decreas coq level essenti compon electron transport chain etc antioxid coq supplement could benefit age process general treatment improv sustain mitochondri function good candid counteract age relat mitochondri dysfunct recent year heighten attent given natur compound modul mitochondri function one famous resveratrol due abil increas mitochondri biogenesi work antioxid agent review discuss recent clinic trial meta analys base resveratrol coq supplement focus compound could improv mitochondri function age
|
D000975;D008928
|
T026;T123;T121;T043;T039;T044
|
36,297,009
|
function complement anti adipogen phytonutri obes prevent manag obes establish risk factor metabol diseas studi explor function complement anti adipogen phytonutri obes prevent manag nine phytonutri select base abil affect express one select adipogen biomark protein phytonutri includ berberin luteolin resveratrol fisetin quercetin fucoidan epigallocatechin gallat hesperidin curcumin select adipogen biomark protein includ ppar srebpc fasn plin fabp catenin individu phytonutri variabl effect express level select adipogen biomark protein collect function complement nine phytonutri suppress de novo fatti acid biosynthesi via negat regul ppar fasn plin fabp express activ glycolysi via posit regul srebpc express preserv cell cell adhes via inhibit catenin degrad primari human subcutan preadipocyt composit nine phytonutri potent longer last anti adipogen effect compar individu phytonutri diet induc obes murin model composit nine phytonutri improv glucos toler reduc weight gain liver steatosi viscer adipos circul triglycerid low densiti lipoprotein cholesterol inflammatori cytokin chemokin function complement anti adipogen phytonutri provid effect approach toward engin novel therapeut prevent manag obes metabol syndrom
|
D009765;D064209
|
T123;T047;T109
|
36,297,008
|
sleep disord western diet influenc psoriasi scope review western diet may trigger sleep disord vice versa singl mutual effect system inflammatori diseas ie psoriasi far fulli elucid time psoriat patient display great burden sleep disord dysmetabol relat unhealthi lifestyl ie diet patient also affect chronic disord deepli modul environment factor ie sleep diet capabl influenc drug respons diseas progress thus aim summar evid literatur may highlight potenti link among psoriasi diet sleep order promot multidisciplinari approach psoriat patient scientif communiti
|
D011565;D012893
|
T047;T048
|
36,297,007
|
famili histori allerg diseas influenc food allergi children japan environ children studi influenc famili allerg histori food allergi offspr japan unknown analyz data nationwid birth cohort studi use logist regress model examin associ matern patern parent histori allerg diseas food allergi atop dermat asthma rhiniti child food allergi year age analysi includ singleton full term mother father children parent histori allerg diseas show signific posit associ child food allergi parent histori allerg diseas adjust odd ratio aor tend higher either parent allerg diseas p trend lt highest aor detect parent food allergi confidenti interv aor either parent food allergi confidenti interv aor attenu still signific posit associ adjust child atop dermat risk factor allergi develop conclus parent allerg diseas signific posit associ child food allergi effect famili histori show stepwis increas risk either parent parent highest risk allerg diseas parent histori food allergi
|
D003876;D005512;D001249
|
T047;T046
|
36,297,006
|
impact dietari intervent obes children asthma prevent control preval asthma obes pediatr popul steadili increas even obes asthma phenotyp postul obes children asthma experi asthma symptom frequent exacerb wors respons treatment also report lower qualiti life compar lean asthmat etiolog factor asthma obes may overlap perhap asthma obes share common genet immunolog origin diet compel modifi factor obes asthma prevent control although relationship two diseas certain multifactori articl analyz impact dietari intervent weight loss obes children asthma prevent control
|
D063766;D001249
|
T033;T047
|
36,297,005
|
hear function nutrit status aviat pilot spain expos high acoust damag nois induc hear loss frequent prevent occup diseas aviat pilot vulner popul spend mani hour expos nois pollut work environ differ studi suggest certain dietari compound may play key role etiolog prevent patholog aim studi relationship link auditori function dietari intak serum biomark pilot expos nois work environ total pilot undergo period medic examin centro de instruccin de medicina aeroespaci madrid spain evalu auditori function assess tonal audiometri energi nutrient intak estim h recal dial tm program serum homocystein hci determin coba tm multi analyz folat vitamin b analyz coba e tm preval hear loss hl hl signific relat age r p flight hour r p multipl linear regress model use assess relationship among hl flight hour serum folat hci serum level hl signific p lt associ flight hour serum folat serum hci nutrit intervent would great interest monitor slow hl progress popul expos nois pollut workplac
|
D009752;D001359
|
T033;T090;T056;T089
|
36,297,004
|
system medicin approach tinnitus comorbid disord despit fact chronic diseas usual occur togeth spectrum possibl comorbid may differ strong patient classic still view distinct diseas entiti consequ often treat uniform therapi unfortun approach take account differ combin symptom comorbid may result differ patholog eg environment genet dietari etc factor requir specif individualis therapeut strategi opinion paper aim put forward differenti system medicin approach diseas patient treatment elabor concept focus interplay tinnitus depress chronic pain view condit characteris varieti phenotyp compos variabl set symptom biomark rather distinct diseas entiti knowledg interplay symptom biomark provid key deeper mechanist understand diseas patholog pave way predict prevent diseas pathway includ personalis effect treatment strategi
|
D014012
|
T184;T047;T037
|
36,297,003
|
oral supplement polyamin spermidin affect hepat pulmonari lipid metabol lean obes mice polyamin spermidin discuss calor restrict mimet therapeut option obes relat comorbid studi test oral spermidin supplement regard system hepat pulmonari lipid metabol differ diet condit male cbl mice fed purifi control cd high sucros hsd high fat hfd diet without spermidin week cd fed mice spermidin decreas bodi adipos tissu weight reduc hepat lipid content hsd induc hepat lipid synthesi accumul hypercholesterolemia affect spermidin supplement bodi weight blood glucos lower hsd compar hsd hfd fed mice show higher bodi fat depot weight prediabet hypercholesterolemia sever liver steatosi alter spermidin within liver spermidin diminish hepat express lipogen transcript factor srebf hsd hfd affect express lipid relat enzym contrast diet spermidin exert minor effect pulmonari paramet thus oral spermidin supplement affect lipid metabol diet depend manner signific reduct bodi fat weight physiolog nutrit posit effect weight blood glucos high sucros intak impact dietari fat relat paramet
|
D006937;D008659
|
T047
|
36,297,002
|
longitudin analysi quadricep muscl strength patient previous covid hospit patient post acut sequela follow mild covid muscl weak promin symptom post acut sequela covid pasc howev studi object longitudin assess muscl strength vari covid sever grade observ studi aim explor preval determin year chang quadricep muscl weak patient discharg covid hospit patient pasc follow mild covid isometr quadricep maxim voluntari contract mvc assess computer dynamomet three visit also subgroup post covid patient quadricep muscl weak muscl thick echo intens determin muscl ultrasound nine upper lower extrem muscl muscl weak found post hospit patient pasc follow mild covid week acut covid wherea year follow mvc modest improv muscl weak preval remain unchang hospit length stay diabet mellitus identifi possibl predictor muscl weak follow covid hospit predictor could identifi pasc follow mild covid ultrasound outcom reveal larg structur abnorm conclus clinic relev muscl weak common covid long term improv poor futur studi relev control group warrant confirm data
|
D052097;D000086382
|
T023;T067;T047
|
36,297,001
|
brd inhibit natur polyphenol target dna damagerepair apoptosi human colon cancer cell epigenet mechan play import role etiolog colorect cancer crc malign due part deregul bromodomain brd function inhibitor bromodomain extratermin bet famili enter clinic trial anticanc agent interest grown acetyl reader protein therapeut target includ non bet member bromodomain contain protein brd report overexpress brd associ poor prognosi crc patient sirna mediat knockdown brd decreas cell viabil activ apoptosi human colon cancer cell coincid increas dna damag seek natur compound brd antagonist molecular dock silico identifi sever polyphenol epigallocatechin gallat egcg equol quercetin aspalathin favor bind energi support bromoscan discoverx isotherm titrat calorimetri experi polyphenol mimick brd knockdown ibrd treatment reduc colon cancer cell viabil inhibit coloni format enhanc dna damag apoptosi normal colon epitheli cell unaffect signifi cancer specif effect find suggest natur polyphenol recogn target brd inhibit might serv use lead compound bromodomain therapeut clinic set
|
D003110;D000970
|
T121;T191;T109
|
36,297,000
|
nutrit gut microbiota allergi develop infant process gut microbiota develop infant current challeng numer factor associ contemporari lifestyl includ diet thorough understand aspect microbiota develop necessari engin strategi modul benefici direct long term consequ human develop health alter success pattern form gut microbiota begin explor requir much investig nevertheless clear gut microbiota develop infanc bear strong associ risk allerg diseas use understand microbi success gut infant need reveal chang taxonom composit also develop function capac time relat diet various environment factor metagenom metatranscriptom studi start produc insight trend function repertoir gene express chang within first year birth understand critic period substanti develop gut microbiota take place relat gut microb host immun establish howev research need focus impact diet chang diet use counteract challeng pose modern lifestyl microbiota develop reduc risk allerg diseas
|
D000069196;D006967;D064307
|
T032;T007;T028;T046;T001
|
36,296,999
|
abdomin obes increas caus cardiovascular diseas cancer mortal risk older adult year follow analysi insuffici evid impact abdomin obes ao mortal older adult therefor object analyz year impact ao assess use differ diagnost criteria caus cardiovascular diseas cvd cancer mortal older adult prospect cohort studi older adult year sociodemograph lifestyl clinic histori laboratori test anthropometr data analyz consid use ao diagnost waist circumfer wc cm women cm men wc cm women cm men increas waist hip ratio whr highest tertil distribut sex multivari cox regress kaplan meier analys perform total individu averag age year particip studi analysi adjust sex age whr associ high risk caus mortal p cutoff point use wc associ increas cvd mortal risk none ao paramet associ cancer mortal increas whr associ higher caus mortal risk factor increas wc risk factor higher cvd mortal older adult
|
D002318;D009369
|
T047;T191
|
36,296,998
|
barrier facilit associ adopt adher mediterranean style diet adult systemat review publish observ qualit studi mediterranean diet meddiet link physic mental health benefit previous research howev suggest adopt adher mediterranean diet might difficult peopl live outsid mediterranean region aim systemat review investig factor influenc adopt adher mediterranean style diet adult age year old identifi publish observ qualit studi follow registr protocol prospero id crd observ qualit studi adult percept experi relev follow mediterranean style diet identifi use systemat search databas medlin cochan librari cinahl web scienc scopus year record februari narrat synthesi undertaken retriev articl studi fulfil inclus criteria includ factor influenc adopt adher meddiet identifi categor financi cognit socio cultur motiv lifestyl access avail sensori hedon demograph similar barrier facilit often report relat healthi eat consumpt specif healthi food except except detail concern specif compon meddiet consider due cultur tradit concern cooler climat suggest overcom barrier facilit specif adopt adher mediterranean diet offer data inform develop futur studi robust methodolog eat behaviour chang offer pragmat approach peopl consum maintain healthi diet
|
D038441
|
T061
|
36,296,997
|
six week follow studi sustain effect prolong water fast refeed marker cardiometabol risk background chronic inflamm insulin resist associ cardiometabol diseas cardiovascular diseas type diabet mellitus non alcohol fatti liver diseas therapeut water fast whole plant food refeed previous shown improv marker cardiometabol risk may effect prevent treatment sustain outcom unknown conduct singl arm open label observ studi six week post treatment follow visit assess effect water fast refeed marker cardiometabol risk method patient voluntarili elect approv complet water fast recruit singl center residenti medic facil primari endpoint describ chang homeostat model assess insulin resist homa ir score end refe visit six week follow visit addit report chang anthropometr measur blood lipid high sensit c reactiv protein hscrp fatti liver index fli observ made baselin end fast eof end refe eor six week follow fu result studi enrol overweightobes non diabet particip complet full studi protocol median fast refeed follow length day respect fu visit bodi weight bw bodi mass index bmi abdomin circumfer ac systol blood pressur sbp diastol blood pressur dbp total cholesterol tc low densiti lipoprotein ldl hscrp fli signific decreas baselin triglycerid tg homa ir score increas eor return baselin valu fu visit conclus water fast whole plant food refeed demonstr potenti long term improv marker cardiovascular risk includ bw bmi ac sbp dbp blood lipid fli hscrp
|
D003924;D007333;D002318
|
T047;T046
|
36,296,996
|
evalu simplifi diet score relat c reactiv protein heavi smoker undergo lung cancer screen aim studi assess relationship adher healthi diet mediterranean diet meddiet c reactiv protein crp italian heavi smoker undergo ldct screen program biomild trial use score calcul simpl questionnair simpl format food frequenc questionnair administ sampl volunt adher healthi diet measur valid point meda two adapt propos us item revis meda item revis meda crp mgl point increas point meda score ci point score ci point score ci invers associ remain statist signific also adjust bodi mass index result show efficaci simplifi score relationship lower level crp popul heavi smoker suggest target nutrit intervent might achiev substanti reduct crp level find prospect test new random studi primari prevent lung cancer screen
|
D008175;D038441
|
T061;T191
|
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