Javtor/biomedical-topic-categorization-validation

PMID int64 35.7M 36.4M	Title/Abstract stringlengths 22 8.78k	MeshTerms stringlengths 7 101	SemanticTypes stringlengths 4 64
36,333,807	jmjd demethyl rig prevent hepat steatosi carcinogenesi hepatocarcinogenesi driven necroinflamm metabol disord under mechan remain larg elus previous found retino acid induc gene rig sensor recogn rna virus innat immun cell main express parenchym hepatocyt liver howev role hepatocarcinogenesi unknown intens investig studi	D006528;D008113;D065626	T047;T191
36,333,805	pediatr tuberculosi outcom factor associ unfavor treatment outcom botswana retrospect analysi global amount research outcom pediatr tuberculosi tb disproportion less adult tb diagnosi paediatr tb also problemat develop countri aim studi describ outcom pediatr tb botswana identifi factor associ unfavor outcom	D015658;D014376	T047
36,333,803	reimburs expens medicin stakehold perspect sma medicin nusinersen dutch coverag lock polici reimburs expens medicin pose grow challeng healthcar worldwid order increas control cost medicin dutch govern introduc coverag lock cl polici cl postpon decis regard reimburs expens medicin detail advic ie cost effect given cl place six year rais mani question concern current evalu known author better understand effect cl stakehold involv may contribut reflect cl process help find way improv evalu dutch polici also relev countri aim optim reimburs procedur expens treatment perform evalu focus cl procedur medicin nusinersen nusinersen first treatment spinal muscular atrophi sma follow ema approv may place cl analysi cost effect ad therapeut valu result advic reimburs limit children younger year start treatment implement august onward	D009841;D009134	T047;T114
36,333,802	zero malaria mirag realiti popul sub saharan africa health transit global burden malaria continu signific public health concern despit advanc made therapeut malaria continu high morbid mortal associ infecti diseas sub saharan africa continu affect diseas unfortun region burden indig health system recent increas lifestyl diseas region current health transit complic situat pose doubl challeng alreadi ail health sector answer continu challeng malaria african union start zero malaria start campaign seek person malaria prevent bring grass root level review discuss contribut sub saharan africa whose popul health transit malaria elimin addit review explor challeng health system countri face may hinder attain zero malaria goal	D019456;D008288	T068;T047
36,333,800	attempt suicid pact covid era psychiatr perspect suicid pact joint activ induc death two individu essenti unavoid characterist mutual consent one partner domin relationship common male usual induc action case one activ carri undiagnos psychopatholog dimens patholog subthreshold trait found enter suicid agreement presenc cluster b person trait narcissist borderlin particular relev domin partner submiss one depend person trait frequent case similar health emerg covid pandem seem lead greater suicid includ suicid pact coupl whose motiv vari includ first financi problem strict follow fear infect abl return home abroad	D000086382;D013405	T033;T047;T067
36,333,799	metagenom proteom analysi bacteri ret communiti proteom profil degum process kenaf bast data microbi communiti function protein associ degum kenaf remain scant analyz microbi communiti associ kenaf hibiscus cannabinus bast fiber ret identifi potenti candid degum bacteria ret liquid collect analyz day day day evalu yield qualiti kenaf fiber differ ret time besid microbi communiti character use metagenom proteom analysi lc msms technolog	D031584	T002
36,333,797	posterior atlantoaxi intern fixat use harm techniqu assist base navig robot treatment atlantoaxi instabl evalu accuraci screw placement use tirobot surgic robot harm procedur assess clinic outcom techniqu	D001268;D013123;D012371;D007593;D013122	T061;T090;T030;T033;T047
36,333,796	occup risk variat nasopharyng cancer nordic countri aim studi estim occup risk variat incid nasopharyng cancer npc larg popul base cohort nordic occup cancer nocca studi	D009303;D016273;D009784	T047;T191;T037
36,333,795	associ renal function screen frequenc renal function declin patient type diabet real world studi primari health care examin associ screen frequenc estim glomerular filtrat rate egfr substanti reduct egfr among type diabet td patient normal egfr mlmin impair kidney function egfr mlmin	D003924;D003928;D051437	T047
36,333,794	identifi complex patient famili medicin potenti benefit case manag short questionnair deriv interm self assess imsa questionnair investig use interm self assess imsa questionnair compon identifi patient candid would benefit case manag cm general practic	D012647;D000071959	T055;T097;T041
36,333,793	prepar student deal consequ workforc shortag among health profession qualit approach healthcar face shortag qualifi healthcar profession pandem brought light fragil balanc affect healthcar system govern realiz system profession work need support differ level strengthen retent workforc health profession educ play import role ensur new generat worker sound person profession compet success face challeng profession practic challeng describ literatur extent consid health profession educ less clear	D006282;D003479	T065;T170;T097
36,333,792	genom landscap immun characterist prognost mutat signatur cervic cancer china studi aim analys genom alter profil immun characterist cohort chines cervic cancer patient understand certain patient benefit molecular target therapi immunotherapi well prognost signific	D002583;D002294;D000230	T191
36,333,791	micturit toilet compar bedpan labor nullipara random control trial bladder overdistens labor may lead prolong postpartum urinari retent hypothes nullipara mobil toilet like achiev satisfactori micturit	D000072296;D007743	T040;T074;T073
36,333,790	whole transcriptom profil chrysanthemum seticusp improv genom annot shed new light mrna mirna lncrna network ray floret disc floret chrysanthemum seticusp emerg model plant speci cultiv chrysanthemum especi studi involv diploid self compat pure line gojo genom sequenc assembl chromosom howev genom annot c seticusp still need improv elucid complex regulatori network speci	D062085;D035683;D031202	T123;T002;T114
36,333,789	optimis calophyllum inophyllum seed oil nanoemuls potenti wound heal agent effici deliveri system calophyllum inophyllum seed oil cso form nanoemuls optimis enhanc stabil ensur therapeut effici potenti agent various biomed applic	D029759	T002
36,333,788	itraq base proteom analysi deinococcus radioduran respons c heavi ion irradi deinococcus radioduran radioduran best known extrem resist divers environment stress factor includ ioniz radiat ir ultraviolet uv irradi oxid stress high temperatur robust dna repair system antioxid system demonstr contribut extrem resist radioduran howev practic studi mechan under radioduran extraordinari resist reli treat strain post treatment recoveri lag phase identifi key element involv direct gene protein chang radioduran stress yet character	D034301;D020450	T196;T007
36,333,787	tadmast comprehens web base tool analysi topolog associ domain chromosom conform captur deriv provid substanti genet data understand chromatin self organ techniqu identifi region high intrasequ interact call topolog associ domain tad tad structur function unit shape chromosom influenc genom express mani domain differ across cell develop impact diseas thus analysi identifi domain provid insight genom regul henc mani approach identifi domain across mani cell line despit avail multipl tool tad detect tad caller speed flexibl result inconsist reproduc remain challeng research area	D002843;D002875	T026;T116
36,333,786	fetuin allevi neuroinflamm traumat brain injuri induc microgli necroptosi regul nrf ho pathway microglia mediat inflammatori respons vital mechan secondari damag follow traumat brain injuri tbi under mechan microgli activ unclear	D000070642;D017628	T025;T037
36,333,785	courag care peopl think attitud toward adolesc contracept use among rwandan famili plan provid adult femal modern contracept user rwanda sexual activ unmarri young women use famili plan compar marri women adolesc import time growth develop often includ initi sexual activ sexual activ adolesc need support access contracept servic prevent negat health outcom sub saharan africa adolesc popul repres larg share total popul proport predict expand time adolesc contracept need larg unmet grow number increas potenti negat health sequela due low use contracept adolesc rwanda grow popul adolesc studi aim explor perspect famili plan provid adult modern contracept user adolesc contracept use inclus adult communiti member studi uniqu contribut research adolesc contracept use sub saharan africa reli primarili perspect adolesc famili plan provid	D005193;D003271	T033;T121;T058
36,333,784	lack causal associ heart failur osteoporosi mendelian random studi heart failur hf implic osteoporosi howev causal remain unestablish sought assess causal associ genet liabil hf osteoporosi use mendelian random mr analys	D010024;D006333	T047;T046
36,333,782	effect covid pandem mental health daili occup activ among health profession colombia nation studi covid pandem place unpreced physic mental burden healthcar worker frequent high risk infect particular low incom countri studi aim assess preval associ factor anxieti depress stress well chang daili occup activ among healthcar profession due covid pandem colombia	D000086382	T047;T067
36,333,780	age distractor resist work memori emot valenc matter emot stimuli use target work memori wm task moder age relat differ wm perform show age associ reduct negat bias phenomenon refer posit effect howev littl research whether emot distractor similar moder effect moreov under neural mechan effect studi studi examin behavior neurophysiolog basi age differ resist emot distractor within wm	D008570;D001288	T041
36,333,779	associ water sanit hygien access preval soil transmit helminth schistosom infect wolayita ethiopia geshiyaro project year intervent assess impact communiti school base water sanit hygien wash intervent reduc infect soil transmit helminth sth schistosom parasit combin deworm wolayita zone ethiopia	D060766;D006376;D006725;D012551;D006373	T047;T204;T167
36,333,778	stem cell phenotyp predict therapeut respons glioblastoma mgmt promot methyl grow bodi evid support presenc popul cell glioblastoma gbm stem cell like phenotyp share certain biolog marker adult neural stem cell includ express sox cd prom nes nestin studi design determin relationship express stem cell marker clinic outcom gbm patient quantifi intens express protein cd sox immunohistochemistri ihc cohort patient idh wildtyp gbm evalu patient outcom use kaplan meier cox proport hazard analysi patient mgmt promot methyl status age predictor overal surviv progress free surviv level sox cd associ outcom univari analysi howev stratif tumor base low high level cd sox express reveal mgmt methyl predictor progress free surviv overal surviv tumor high level express cd sox tumor low level express cd sox show relationship mgmt methyl surviv relationship mgmt stem cell marker confirm second patient cohort tcga dataset result show stratif gbm level express cd sox improv prognost power mgmt promot methyl status identifi low express group clinic outcom associ mgmt promot methyl status high express group outcom strong associ mgmt promot methyl status find support concept presenc high stem cell phenotyp gbm mark express sox cd may associ clinic respons treatment	D005909;D001932	T191
36,333,777	novel dual digest symbiosi scale nutrit immun system holobiont rimicari exoculata deep sea hydrotherm vent area depriv light anim reli chemosynthet symbiont nutrit symbiont may locat cuticl insid modifi organ special cell nonetheless mani anim open function digest tract vent shrimp rimicari exoculata fuel main gill chamber symbiont also complet digest system symbiont found shrimp foregut midgut role remain unknown use genom resolv metagenom separ foregut midgut sampl taken specimen live three contrast site along mid atlant ridg tag rainbow snake pit reveal genet potenti	D033364;D060086	T070;T204
36,333,776	macrophag polar toward phenotyp nf b signal patient behet diseas macrophag key innat immun cell implic pathogenesi behet diseas bd macrophag polar play pivot role inflammatori respons studi aim investig role bd serum phenotyp function macrophag polar	D016328;D001528	T129;T047;T116
36,333,775	contextu factor influenc implement new midwif educ programm india qualit studi indian govern commit educ midwiv accord intern norm goal critic midwiv provid evid base high qualiti midwiferi care need explor contextu factor influenc new midwiferi educ programm henc aim studi explor contextu factor influenc implement nation midwiferi educ programm midwiferi educ futur nurs practition midwiferi npms india qualit research design use data collect focus group discuss n total particip repres seven nation intern organis support indian govern midwiferi initi transcrib interview analys use content analysi studi contextu factor influenc implement new midwiferi educ programm india show organis administr process complex develop midwiferi educ nurs practition midwiferi need fast track educ educ futur midwiv india elsewher similar set could benefit effort simplifi organis administr process parallel mobil innov teach learn approach bridg theori practic	D008880;D009721	T091;T097
36,333,774	high grade desmoplast infantil astrocytoma year old child syndrom case report syndrom common chromosom abnorm human associ central nervous system tumor primari acut lymphoblast leukemia germinoma desmoplast infantil astrocytoma yet report syndrom desmoplast infantil astrocytoma rare intracrani tumor most occur first year life usual present larg aggress tumor solid cystic compon genet link braf mutat despit rapid growth pattern usual favor prognosi neurosurg excis presenc extrem rare genet link tumor combin syndrom common human genet defect make novel clinic present also rais research worthi question undiscov link two genet disord	D001254;D001932;D004314;D018303;D058627	T019;T047;T191
36,333,773	levonorgestrel releas intrauterin devic plus metformin megestrol acet plus metformin fertil spare treatment atyp endometri hyperplasia earli endometri carcinoma prospect random blind endpoint design trial protocol endometri adenocarcinoma ec fifth common cancer women worldwid standard treatment ec includ hysterectomi result loss reproduct function thus conserv treatment patient strong demand progestin therapi wide accept main fertil spare treatment young women endometri hyperplasia atypia eha well differenti endometrioid endometri cancer trial investig effect conserv treatment obes women earli stage ec	D004714;D007436;D008687;D016889	T121;T109;T191;T047;T074
36,333,772	singl cell profil cd spinal cord cell reveal microgli b cell heterogen crosstalk follow spinal cord injuri immun cell play crucial role spinal cord injuri sci howev incomplet knowledg immun contribut injuri repair hinder develop sci therapi leverag singl cell observ describ key popul immun cell present spinal cord chang transcript profil uninjur subacut chronic stage sci	D017628;D013119	T025;T037
36,333,771	stellat ganglion block reliev acut lung injuri induc sever acut pancreat via mir psocsjakstat axi acut lung injuri ali preval complic sever acut pancreat sap also lead contributor respiratori failur even death sap patient intend investig function mechan stellat ganglion block sgb amelior sap induc ali sap ali engin sap ali model rat treat sgb stain dri wet method implement evalu patholog alter tissu pulmonari edema rat serum chang profil tnf il il il examin profil mir p socsjakstat detect function assay perform confirm role mir p modul socsjakstat pathway pulmonari epitheli cell find reveal sgb vigor allevi sap rat lung tissu damag lung edema lessen generat pro inflammatori cytokin tnf il il sgb enhanc soc express hamper mir p suppress jakstat pathway activ evidenc mechan studi mir p target utr soc repress express henc result jakstat pathway activ anim trial discov sgb amelior sap ali boost soc express mitig level pro inflammatori factor mir p plasma vitro mir p overexpress substanti facilit pulmonari epitheli cell apoptosi inflamm jakstat pathway activ restrain soc express work hint sgb could modul mir psocsjakstat axi allevi sap ali	D010195;D055371;D011654;D035683	T123;T037;T114;T047;T046
36,333,770	preval manag chronic pain chines popul find china pain health index chronic pain common diseas peopl worldwid suffer compar research preval manag chronic pain develop countri relat lack research field china research aim construct china pain health index cphi evalu current status preval manag chronic pain chines popul	D059350	T184;T047
36,333,769	knee osteoarthr pre screen questionnair kop cross cultur adapt measur properti brazilian version kop brazilian version despit criteria alreadi establish classif knee osteoarthr oa radiograph andor clinic knee oa diagnosi usual occur case fulli manifest advanc diseas make health promot prevent function rehabilit advanc stage diseas less effect addit radiograph knee oa generat financi cost health servic therefor develop valid screen instrument assess probabl develop progress knee oa would great valu clinic practic scienc	D020370	T047
36,333,768	sever acut malnutrit recoveri rate still minimum standard predictor time recoveri among month old children healthcar set southwest ethiopia despit current avail scientif proven treatment nation guidelin sam recoveri rate still consider behind expect continu devast impact five children identifi predictor time recoveri might help reach minim criterion establish nation sphere decreas child mortal therefor current studi assess time recoveri predictor among children age month admit sam healthcar set southwest ethiopia	D000067011;D011014	T047;T050
36,333,766	longitudin phenotyp patient acut respiratori distress syndrom multi databas studi previous identifi phenotyp acut respiratori distress syndrom ard limit disregard tempor dynam aim identifi longitudin phenotyp ard test prognost predict enrich longitudin phenotyp develop simplifi model phenotyp identif	D012128	T047
36,333,764	effect lncrna mirhg modifi mscs exosom deliveri synergist attenu vein graft intim hyperplasia mesenchym stem cell mscs use repair tissu injuri howev treatment effect satisfactori investig whether lncrna mirhg could promot surviv migrat mscs oxid stress mimic vivo environ furthermor studi protect effect exosom secret mscs transfect mirhg endotheli cell studi aim determin whether exploit mscs exosom modifi lncrna mirhg would exert synergist therapeut effect attenu vein graft intim hyperplasia effect	D055354;D062085;D059630	T026;T123;T025;T114
36,333,763	quantit ct analysi predict esophag fistula patient advanc esophag cancer treat chemotherapi chemoradiotherapi esophag fistula one serious complic chemotherapi chemoradiotherapi crt advanc esophag cancer studi aim evalu perform quantit comput tomographi ct analysi establish practic imag model predict esophag fistula esophag cancer patient treat chemotherapi chemoradiotherapi	D004938;D004937	T191;T190
36,333,761	trem defici impair recoveri phagocytosi dysregul myeloid gene express virus induc demyelin trigger receptor express myeloid cell trem play protect role neurodegen diseas contrast trem function exacerb tissu damag respiratori viral liver infect therefor investig role trem viral encephalomyel model associ promin th mediat antivir immun lead demyelin	D001921;D003711	T023;T046;T047
36,333,759	health technolog assess support respons public health emerg public health emerg phes covid crisi threat global health public order recommend countri bolster phe respons invest health technolog assess hta defin systemat process gather pertin inform evalu health technolog medic econom social ethic standpoint present exampl hta organ low middl incom countri adapt support phe relat decis covid describ way hta help respons phe turn advoc hta capac develop global increas institut accept method build block prepared respons futur phes final long term potenti hta strengthen health system embed confid transpar scientif polici recogn	D013673;D000086382	T058;T067;T047
36,333,755	persian version psycholog flexibl sport scale psychometr studi grow bodi research suggest psycholog flexibl pf import psycholog construct relat psycholog health human perform psycholog flexibl sport scale pfss first general scale assess sport relat pf far pfss yet valid context sweden therefor current studi sought investig persian version pfss p pfss extend investig psychometr properti pfss iranian athlet	D013177	T056
36,333,754	microbi communiti associ parascari spp infect juvenil hors parasit nematod includ larg roundworm colloqui known ascarid affect health well livestock anim worldwid equin ascarid parascari spp import parasit juvenil hors first ascarid develop widespread anthelmint resist microbiota shown import factor fit mani organ includ parasit nematod endosymbiot wolbachia exploit treatment filariasi human	D001199;D017191;D006734;D064307	T032;T204;T028;T047;T001
36,333,753	role person trait leisur activ predict wellb young peopl relationship wellb person studi extens studi examin period adolesc emerg adulthood moreov influenc contextu factor engag leisur activ rare consid	D007899;D010551	T078;T056;T041
36,333,752	bifidobacteri carbohydratenucleosid metabol enhanc oxid phosphoryl white adipos tissu protect diet induc obes comparison gut microbiom lean obes human reveal obes associ gut microbiom plus chang numer environment factor includ high fat diet hfd report two speci bifidobacterium crucial control metabol paramet korean popul	D001644;D000069978	T007
36,333,751	effect earli stellat ganglion block cerebr vasospasm aneurysm subarachnoid hemorrhag block cvs studi protocol random control trial stellat ganglion block report expand cerebr vessel allevi vasospasm aneurysm subarachnoid hemorrhag howev causal relationship earli stellat ganglion block cerebr vasospasm prevent yet establish purpos studi explor effect safeti earli stellat ganglion block prevent treatment cerebr vasospasm delay cerebr ischemia	D020301;D013345;D002545	T047;T046
36,333,749	fit base risk stratif model effect screen colorect neoplasia earli onset colorect cancer chines popul nationwid multicent prospect studi fulli valid risk stratif strategi establish china colonoscopi resourc limit aim develop valid fecal immunochem test fit base risk stratif model colorect neoplasia cn individu recruit center nationwid random alloc deriv n valid cohort n multivari logist analys perform develop nation colorect polyp care ncpc score form risk stratif model along fit ncpc score develop eight independ predict factor divid three level low risk lr intermedi risk ir high risk hr individu ir hr ncpc score fit classifi increas risk individu risk stratif model recommend colonoscopi irhr ncpc score show higher preval cns vs p acn vs p lr also confirm valid cohort similar relat risk predict perform demonstr non specif gastrointestin symptom nsgs asymptomat cohort risk stratif model identifi cn acn crc guid individu receiv colonoscopi identifi earli onset acn earli onset crcs young individu receiv colonoscopi risk stratif model show good risk stratif abil cn earli onset crcs chines popul includ individu nsgs young age	D055088;D015179	T060;T058;T191
36,333,747	mitochondri protect effect caus administr mefenam acid sepsi pathophysiolog sepsi may involv activ nod type receptor contain pyrin domain nlpr mitochondri oxid damag one primari essenti oxid product oxoguanin oxog accumul mitochondri dna mtdna induc cell dysfunct death lead hypothesi mtdna integr crucial maintain neuron function sepsi sepsi modul nlrp activ critic mefenam acid mfa potent drug reduc inflammasom activ attenu acut cerebr inflammatori process thus studi aim evalu administr mfa implic reduct inflammatori paramet mitochondri damag anim submit polymicrobi sepsi test hypothesi adult male wistar rat submit cecal ligat perfor clp model sepsi induct receiv inject mfa dose mgkg steril salin mlkg h sepsi induct frontal cortex hippocampus dissect analyz level tnf il il oxid damag thiobarbitur acid reactiv substanc tbar carbonyl dcf da oxid paramet protein express mitochondri transcript factor tfam nlrp oxog bax bcl ioniz calcium bind adaptor molecul iba activ mitochondri respiratori chain complex observ septic group structur studi show increas proinflammatori cytokin mediat increas activ nlrp signific oxid damag higher product reactiv oxygen speci ros mitochondria damag mtdna also observ increas oxog level lower level tfam ngf addit group increas pro apoptot protein iba posit cell howev mfa dose mgkg decreas inflammasom activ reduc level cytokin oxid damag increas bioenerget efficaci reduc product ros oxog increas level tfam ngf bcl reduc microgli activ result suggest mfa induc protect central nervous system earli onset sepsi	D008528;D018805	T121;T047;T046;T109
36,333,745	bodi stuf apprehens result distal esophag impact case report review literatur bodi stuf bodi pack two method conceal illicit drug bodi stuf defin oral ingest illicit drug typic avoid law enforc detect consequ possess may present serious medic emerg patient common bodi stuffer ingest possibl larg unknown quantiti illicit substanc avoid detect drug apprehens ingest typic hasti impuls therefor substanc ingest rare packag way would consid safe ingest	D000075066;D005547;D013287	T016;T109;T131;T020;T037;T054;T072
36,333,744	effect day storag differ temperatur detect felin kidney injuri molecul urin human kidney injuri molecul kim biomark acut kidney injuri quantifi urin preliminari investig cat experiment induc acut kidney injuri show kim urin concentr correl kidney injuri histopatholog score later flow assay lfa recent becom avail patient side felin kim measur vitro paramet assay yet determin object studi determin detect kim urin store differ temperatur time establish linear rang lfa assess intra assay repeat measur result ten urin sampl rang kim concentr store room temperatur c c c test lfa day concentr kim sampl signific differ day valu except one sampl store day room temperatur yield signific higher valu assay result correl coeffici mean coeffici variat sampl slope curv expect versus measur valu sampl dilut two fold nine time result linear dilut	D058186;D002371	T047;T037
36,333,742	music famili interact mufasa protocol articl rct studi general mental health interperson skill famili crucial children develop futur research suggest link particip music activ individu sens mental health well effect object measur health qualiti life social skill rehabilit various kind howev denmark mani servic famili school age children year focus prevent strengthen famili interact herebi minimis risk children thrive develop optim term social emot skill compet purpos studi investig effect share music activ famili interact parent stress child well	D009146;D009147	T061;T170
36,333,741	pilot studi evalu semi rigid flexibl cathet less invas surfact administr preterm infant respiratori distress syndrom random control trial respiratori distress syndrom mani neonatolog center worldwid perform minim invas surfact applic prematur infant use small diamet cathet endotrach intub surfact administr	D011663;D012127	T123;T047;T121;T109
36,333,740	impact suboptim inappropri treatment healthcar resourc use cost among patient uncompl urinari tract infect analysi integr deliveri network electron health record although uncompl urinari tract infect uuti occur femal patient without urolog abnorm histori urolog procedur complic comorbid one common communiti infect unit state us limit data avail concern associ antibiot resist suboptim prescrib econom burden uuti examin preval suboptim antibiot prescrib antibiot resist effect healthcar resourc use cost	D057286;D014552	T047;T170;T073
36,333,739	intermitt prevent treatment malaria amongst pregnant women give birth centr hospitali rgional paul moukambi de koula moutou southeastern gabon evalu malaria control strategi pregnant women essenti object studi determin factor influenc antenat care anc visit attend complet intermitt prevent treatment sulfadoxin pyrimethamin iptp sp impact health pregnant women newborn babi live semi urban rural area southeastern gabon	D015597;D000962;D008288	T121;T047
36,333,738	viral communiti wide auxiliari metabol gene differ lifestyl habitat host viral encod auxiliari metabol gene amg import toolkit modul host metabol microbi driven biogeochem cycl although function amg extens report numer environ still know littl driver shape viral communiti wide amg composit natur ecosystem explor driver viral communiti wide amg composit critic deeper understand complex interplay among virus host environ	D001435;D014780	T005
36,333,737	loss brca trp adult mous mammari ductal epithelium result develop hormon receptor posit hormon receptor negat tumor depend inactiv rb famili protein breast cancer heterogen diseas sever histolog molecular subtyp model repres subtyp essenti translat research aim improv clinic strategi target therapeut	D042361;D001943;D015674	T023;T191;T024
36,333,736	sex age differ associ fatti liver index defin non alcohol fatti liver diseas cardiometabol risk factor cross section studi despit extens scientif evid accumul epidemiolog risk factor non alcohol fatti liver diseas nafld evid explor sex age relat differ remain insuffici present cross section studi aim investig possibl sex differ preval fli defin nafld well associ common risk factor across differ age group larg sampl spanish work adult	D065626;D003920;D006973;D002318	T047
36,333,735	infant congenit heart defect proteinuria case report branchio oto renal bor syndrom rare autosom disord wide varieti clinic manifest high degre heterogen typic clinic manifest bor syndrom includ deaf preauricular fistula abnorm gill slit renal malform howev atyp phenotyp congenit hip dysplasia congenit heart anomali facial nerv paresi rare bor syndrom might easili misdiagnos congenit disord	D019280;D006330	T019;T047
36,333,733	develop psychometr assess sexual reproduct health profil women type diabet mellitus improv sexual reproduct health srh women type diabet mellitus tdm plan formul basi exist situat situat examin valid tool conform specif domain srh target group present studi seek develop assess psychometr properti srh profil women tdm	D003922;D000074384	T047;T032
36,333,730	diagnosi tuberculosi autoimmun hepat system lupus erythematosus overlap syndrom case report ampl evid indic immunosuppress therapi immun dysregul system lupus erythematosus increas risk tuberculosi interest case report suggest tuberculosi could also risk factor system lupus erythematosus autoimmun diseas	D019693;D008180;D014376	T047
36,333,729	safeti efficaci corticosteroid ard patient systemat review meta analysi rct data acut respiratori distress syndrom ard acut critic diseas among children adult previous studi shown administr corticosteroid remain controversi therefor meta analysi random control trial rcts perform evalu safeti efficaci corticosteroid	D006854;D012128	T125;T121;T047;T109
36,333,727	implement coach mclung sm primari care use cluster random step wedg trial design asthma preval chronic diseas difficult manag associ mark dispar outcom one promis approach address dispar share decis make sdm method patient provid cooper make decis asthma care sdm associ improv outcom patient howev time constraint staff avail note implement barrier use health inform technolog solut may facilit util sdm coach mclung sm collabor web base applic involv pediatr patient caregiv provid person experi gather patient report data background logic provid decis support audienc develop well inform treatment plan togeth goal studi evalu implement coach mclung sm intervent primari care	D000080536;D001249	T047;T041
36,333,725	olfactori marker protein contain leucin rich domain loop import nuclear export olfactori marker protein omp cytosol protein express matur olfactori receptor neuron orn omp modul camp signal regul olfactori sensat axon target omp small solubl protein passiv diffus nucleus cytoplasm expect howev omp most situat cytosol spars detect nuclei subset orn hypothalam neuron heterolog omp express cultur cell omp enter nucleus associ transcript factor howev omp retain cytosol rest unclear omp propos affect cell differenti import understand omp distribut cytoplasm nucleus elucid structur profil omp appli sever bioinformat method multipl sequenc align msa omp protein sequenc rank evolutionarili conserv residu addit previous report camp bind domain identifi leucin rich domain loop omp introduc mutat leucin rich region heterolog express mutant omp hekt cell mutat alanin increas nuclear distribut omp quantifi immunocytochemistri western blot therefor conclud omp contain leucin rich domain import nuclear transport	D018034	T026;T025
36,333,724	electroacupunctur effect therapi tapia syndrom transor intub general anesthesia case report review literatur tapia syndrom rare complic airway manipul general anesthesia injuri vagus nerv x hypogloss nerv xii transor intub primari caus diseas typic symptom includ hoars dysarthria dysphagia tongu muscl atrophi tongu deviat toward affect side report case tapia syndrom treat electroacupunctur acceler recoveri process discuss potenti mechan behind find base previous research	D015671;D020437	T061;T047
36,333,723	preval malaria risk factor lake tana surround area northwest ethiopia ethiopia malaria major concern health socio econom develop countri occurr peak agricultur activ factor environment human host parasit vector determin malaria transmiss therefor present studi conduct determin preval associ factor malaria among febril patient visit select health centr	D008288;D016778;D016780	T047
36,333,720	acut effect niv peripher muscl function aerob perform patient chronic obstruct pulmonari diseas pilot studi non invas ventil niv reduc respiratori load demand peripher muscl	D063087;D029424	T061;T047
36,333,719	mg relat lncrnas predict prognosi regul immun microenviron lung squamous cell carcinoma n methylguanosin mg long non code rnas lncrnas wide studi cancer found use assess tumor progress howev role mg relat lncrnas lung squamous cell carcinoma lusc remain unclear thus crucial identifi mg associ lncrnas definit prognost valu studi aim investig prognost valu correl tumor mutat burden impact tumor immun microenviron mg relat lncrnas lusc method lusc transcriptom data clinic data download cancer genom atlas mg relat lncrna mrna co express network construct use pearson correl analysi cox regress analys use determin risk model mg associ lncrnas prognost valu risk signatur verifi use kaplan meier method receiv oper characterist curv analysi princip compon analysi nomogram base risk score clinic characterist develop gene set enrich analysi use function annot analyz risk signatur associ among risk signatur tumor mutat burden tumor infiltr immun cell analyz rt qpcr use investig express mg relat lncrnas lusc cell cytolog function srp verifi wound heal assay transwel assay	D062085;D008175;D002294;D002289	T123;T191;T114
36,333,718	studi protocol glow studi maximis treatment option recurr glioblastoma patient whole genom sequenc base diagnost prospect multicent cohort studi glioblastoma gbm common glial primari brain tumour without except lethal everi year approxim patient diagnos heterogen diseas netherland despit neurosurgeri chemo radiat therapi tumour inevit recur current gold standard time recurr treatment option limit unfortun result dedic trial new drug disappoint goal project obtain evid chang standard care soc procedur includ whole genom sequenc wgs consequ adapt care guidelin specif patient group poor prognosi offer optim time benefit novel therapi even absenc tradit registr trial small volum cancer indic	D005909;D001932	T191
36,333,717	communiti social capit health relat qualiti life among empti nest elder western china moder effect live arrang present empti nest phenomenon becom serious world especi china health problem deserv attent therefor purpos studi explor impact communiti social capit health relat qualiti life empti nest elder	D011788;D066270	T078;T169
36,333,716	examin variat implement intervent address stillbirth nation subnat level experi uganda current global burden stillbirth disproportion affect region sub saharan africa uganda locat respond burden polici made nation level diffus centr translat servic deliveri district level charg implement decentr health servic arrang variat emerg whenev polici recommend move nation subnat level aspect often lost along way tool avail facilit knowledg determin polici innov implement within healthcar system howev extent appli explain variat implement intervent address stillbirth reduct uganda remain scant aim articl examin variat implement intervent address stillbirth nation subnat level uganda use consolid framework implement research cfir	D050497;D003695	T033;T058;T093
36,333,715	accuraci thorac pedicl screw placement adolesc idiopath scoliosi patient use entri point identifi new landmark comput tomographi studi although thorac pedicl tp screw gain increas popular surgic treatment adolesc idiopath scoliosi ai patient question remain accur select entri point tp screw placement patient main object present studi evalu accuraci tp screw placement ai patient use entri point identifi new landmark	D012600;D065289;D013123;D007738	T061;T047;T074;T190
36,333,714	covert contracept use amongst urban poor accra ghana experi health provid estim one third women ghana use contracept without knowledg partner phenomenon known covert contracept use ccu research ccu date focus individu women neglect role health system studi explor ccu urban poor communiti accra ghana experi perspect health provid	D003270;D006282	T121;T039;T097
36,333,713	childhood immun age appropri vaccin indonesia childhood immun cost effect way protect individu communic diseas howev although larg literatur childhood immun indonesia pauciti research age appropri measl dtwp vaccin inequ immun coverag across indonesia	D017589;D008457	T058;T047
36,333,712	associ social integr particip product loss among person chronic pain registri base cross section studi examin associ factor social inclus particip product loss employ person chronic pain assess interprofession pain rehabilit programm hypothes factor social inclus particip work relat social factor signific associ product experienc chronic pain expect moder effect	D059350	T184;T047
36,333,710	two year effect erenumab resist chronic migrain prospect real world analysi control real world evid demonstr efficaci calcitonin gene relat peptid cgrp monoclon antibodi mab migrain howev data one year sustain effect cgrp mab resist chronic migrain cm spars method two year real world prospect analysi ongo singl centr audit conduct patient resist cm patient receiv month erenumab six month assess effect respond consid achiev least reduct month migrain day mmd month compar baselin secondari outcom also analys includ chang headach impact test version hit	D000077221;D008881	T121;T047
36,333,709	plant sex affect plant microbiom assembl dioecious populus cathayana tree differ soil nitrogen condit dioecious plant coevolv divers plant microbiom crucial fit product host sexual dimorph morpholog physiolog gene express may relat differ microbi composit affect male femal fit differ environ howev sex specif impact ecolog process control microbiom assembl well known studi populus cathayana male femal plant differ nitrogen condit hypothes male femal differ affect bacteri fungal communiti rhizospher soil root old leav young leav physiolog trait transcriptom profil male femal plant investig reveal potenti mechan control microbiom assembl	D032107;D064307	T001;T032;T028;T002
36,333,708	preliminari experi obliqu occlus techniqu robot assist infrahepat inferior vena cava thrombectomi step step procedur short term outcom aim compar oncolog outcom obliqu occlus techniqu tradit techniqu robot assist radic nephrectomi rarn inferior vena cava ivc thrombectomi explor safeti effect obliqu occlus techniqu	D002292;D007680;D012371;D020246	T090;T047;T191;T046
36,333,707	primari care util patient newli diagnos cancer covid pandem popul base studi covid pandem great impact primari care cancer care studi primari care util ontario canada chang patient newli diagnos cancer prior covid pandem compar diagnos non pandem year	D000086382;D009369	T047;T191;T067
36,333,705	neonat heavi metal level associ sever neonat respiratori distress syndrom case control studi case control studi aim compar lead pb cadmium cd arsenic level neonat respiratori distress syndrom nrds level normal neonat test associ sever nrds indic level serum surfact protein sp cord blood cardiac troponin ctni high sensit c reactiv protein hs crp	D001151;D019216;D012127	T121;T196;T131;T047
36,333,704	budget impact analysi subcutan infliximab ct p sc treat inflammatori bowel diseas big european e countri european medicin agenc approv infliximab subcutan sc treatment inflammatori bowel diseas new mode infliximab administr reduc outpati visit cost intraven iv administr articl describ budget impact analysi introduc infliximab sc big european e market germani franc itali spain uk year healthcar payer perspect	D000911;D015212	T129;T047;T116
36,333,702	heterogen earli ill cours korean patient bipolar disord replic stage model clinic stage bipolar disord bd requir applic real world data next step hypothesi studi use stage model analyz long term cours bd korean patient base clinic featur treatment respons map progress bipolar ill earli phase onset ill	D001714;D009771	T048
36,333,701	presenc plasmodium malaria plasmodium knowlesi near malaria elimin set western indonesia indonesia progress toward malaria elimin achiev goal intervent measur must address cover plasmodium speci comprehens control measur surveil programm must intensifi studi aim determin preval microscop submicroscop malaria langkat district north sumatera provinc indonesia	D016790;D008288	T047;T204
36,333,700	identif express purif dna cytosin methyltransferas short recognit sequenc dna methyltransferas mtase enzym induc methyl one repres epigenet modif dna also use tool analyz epigenom howev regard dna cytosin methyl mtase identifi far drawback recognit sequenc overlap intrins dna methyl mammalian cell andor recognit sequenc long fine epigenet map identifi mtase short recognit sequenc never overlap cg dinucleotid systemat investig candid enzym identifi use databas search show high similar known cytosin mtase recogn short sequenc	D015254;D019175	T126;T116;T044
36,333,699	applic logist differenti equat model earli warn infecti diseas jilin provinc still relat serious diseas burden infecti diseas warn time differ infecti diseas implement intervent import logist differenti equat model use predict earli warn infecti diseas aim studi compar diseas fit effect logist differenti equat lde model general logist differenti equat glde model first time use data multipl infecti diseas jilin provinc calcul earli warn signal differ type infecti diseas use two model jilin provinc solv diseas earli warn schedul jilin provinc throughout year	D003141;D009107;D012541;D058872	T047;T067
36,333,698	must cut long stink thing uncov live experi uncircumcis pokot women north eastern uganda femal circumcis remain domin practic among pokot north eastern uganda paper explor live experi uncircumcis pokot women continu live communiti practic cherish	D002944;D012749;D015658	T061;T047
36,333,697	childhood maltreat suicid ideat chines children adolesc mediat role mind childhood maltreat cm associ suicid ideat si children adolesc yet mediat role mind associ remain unclear studi aim test mediat mind cm si associ among larg sampl chines children adolesc	D064866;D002649	T041;T048
36,333,696	toddler unusu sever polyarticular arthriti lung involv case report copa syndrom rare hereditari inflammatori diseas caus mutat gene encod coatom protein subunit alpha caus excess product type interferon case remind general paediatrician highlight relev associ arthriti lung involv toddler	D001171;D017563	T047
36,333,695	increas diaphragm echodens correl postop pulmonari complic patient major abdomin surgeri prospect observ studi associ increas morbid mortal postop pulmonari complic ppcs often occur major abdomin surgeri diaphragmat dysfunct suggest play import role develop ppcs diaphragm echodens use indic diaphragm function studi aim determin whether diaphragm echodens could predict occurr ppcs patient major abdomin surgeri	D003964;D000005	T023;T029
36,333,694	three dimension microenviron regul gene express function tight junction dynam ipsc deriv blood brain barrier microvessel blood brain barrier bbb play pivot role brain health diseas bbb brain microvascular endotheli cell bmec connect tight junction regul paracellular transport express special transport system regul transcellular transport howev exist vitro model bbb display variabl accuraci across wide rang characterist includ geneprotein express barrier function use isogen famili fluoresc label ipsc deriv bmec like cell ibmec brain pericyt like cell ipc within two dimension confluent monolay three dimension tissu engin microvessel explor microenviron regul gene express function vitro bbb show microenviron shear stress cell ecm interact cylindr geometri increas bbb phenotyp endotheli ident alter angiogen cytokin respons synergi pericyt co cultur tissu engin microvessel incorpor junction label ibmec enabl studi real time dynam tight junction homeostasi respons physic chemic perturb	D001812;D057026	T023;T025
36,333,693	long term evalu safeti biolog effect korean red ginseng panax ginseng long term vivo studi although korean red ginseng krg safe find evalu mo long studi safeti verifi mo krg administr clinic studi long term studi beyond mo insuffici studi investig safeti efficaci mo krg administr	D005894	T002
36,333,692	effect vitamin supplement sever stress urinari incontin premenopaus women vitamin insuffici random control clinic trial urinari incontin especi stress urinari incontin sui one problem experienc premenopaus women given role vitamin enhanc muscl strength function studi explor effect vitamin supplement sui premenopaus women	D014550;D014549;D014808	T047;T046
36,333,691	explor knowledg parent caregiv cancer symptom children observ studi regard need educ tool health promot low middl incom countri although case childhood cancer unlik prevent today standard children cancer cure howev dispar surviv exist among countri mexico overal surviv childhood cancer diagnos advanc stage therefor parent caregiv must optim knowledg earli sign symptom childhood malign larg non specif studi design explor current knowledg childhood cancer among parent caregiv mexico identifi need educ health promot low middl incom countri	D017028;D009369	T099;T098;T191;T097
36,333,690	surveil tobacco use among young adolesc trend predictor across three year souss tunisia develop countri overal decreas tobacco use last decad tunisia nation strategi reduc tobacco use set sinc howev strategi rare evalu object current studi examin trend tobacco use among middl schoolchildren governor souss tunisia determin predictor experiment	D012907;D064424	T055
36,333,689	pathway ovarian cancer diagnosi qualit studi ovarian cancer often diagnos late stage surviv poor qualit narrat patient pathway ovarian cancer diagnos may identifi opportun earlier cancer detect consequ earlier stage diagnosi	D055088;D010051	T060;T058;T191
36,333,688	associ serum vitamin level viscer adipos tissu among adolesc cross section observ studi nhane recent year obes vitamin defici preval among adolesc improv knowledg link vitamin viscer adipos tissu vat essenti health adolesc studi aim examin connect serum vitamin level vat mass among adolesc particip unit state	D050152;D014808	T047;T024
36,333,687	effect tracheal tube cuff inflat alkalin lidocain versus air hemodynam respons extub post oper airway morbid children prospect observ cohort studi ethiopia endotrach tube inflat cuff use manag maintain airway general anesthesia children later pressur exert inflat endotrach tube cuff tracheal mucosa exceed capillari perfus pressur patient may complain cough sore throat hoars postop period studi aim assess effect tracheal tube cuff fill alkalin lidocain versus air hemodynam paramet chang extub post oper airway morbid children	D008012;D010612	T121;T047;T184;T109
36,333,686	evalu chang negat posttrauma cognit mechan ptsd sever chang two separ intens treatment program veteran wealth evid illustr reduct negat posttrauma cognit npcs predict improv posttraumat stress disord ptsd symptom treatment yet specif tempor arrang chang construct less well understood studi examin tempor associ npc chang ptsd symptom chang two distinct intens ptsd treatment sampl	D014728;D013313	T098;T048
36,333,684	construct novel cuproptosi relat gene signatur predict prognosi estim tumor immun microenviron status papillari thyroid carcinoma cuproptosi new form program cell death recent report close relat tumor progress howev signific cuproptosi relat gene crgs papillari thyroid carcinoma ptc still unclear therefor studi aim investig role crg signatur prognosi predict immunotherapeut effect estim patient ptc	D015972;D013964	T045;T191
36,333,683	whether surgic resect biopsi make differ singl lesion primari central nervous system lymphoma singl center retrospect cohort studi primari central nervous system lymphoma pcnsl rare aggress diseas role surgic resect pcnsl alway center debat investig clinic follow data singl lesion pcnsl oper center focus comparison surgic resect biopsi	D016543;D008223	T191
36,333,682	point care c reactiv protein test result acut infect children primari care observ studi acut infect common reason children consult primari care serious infect rare differenti self limit ill remain challeng lead inappropri antibiot prescrib point care c reactiv protein test use guid antibiot prescrib adult howev children use remain unclear purpos studi assess point care crp test level respect patient characterist care set preliminari diagnosi manag	D007239;D011014	T047;T046;T050
36,333,681	covid impact psycholog health latinx transgend non binari individu mainland unit state puerto rico mix method studi covid pandem continu generat unpreced impact aspect everyday life across world howev histor current margin ident ie gender ethnic alreadi experi wide rang structur inequ disproport impact ltnb particular risk popul lie intersect raceethn gender ident languag migrat status geograph locat among other could increas covid health relat risk dispar object studi examin impact key social determin health ie gender ident countri health insur employ among sampl ltnb individu	D000086382;D063106	T047;T098;T067
36,333,680	phase ii studi carboplatin etoposid plus durvalumab previous untreat extens stage small cell lung cancer es sclc patient poor perform status ps neja studi protocol small cell lung cancer sclc account lung cancer limit prognosi approxim one third sclc patient poor perform status ps patient extens stage es sclc poor ps poor prognosi popul overal surviv carboplatin etoposid treatment month treatment develop unmet medic need recent combin anti pd l ligand program cell death antibodi platinum base chemotherapi becom standard care es sclc patient good ps ps hypothes combin anti pd l antibodi durvalumab carboplatin etoposid would feasibl effect patient	D055752;D008175	T191

36,333,807

jmjd demethyl rig prevent hepat steatosi carcinogenesi hepatocarcinogenesi driven necroinflamm metabol disord under mechan remain larg elus previous found retino acid induc gene rig sensor recogn rna virus innat immun cell main express parenchym hepatocyt liver howev role hepatocarcinogenesi unknown intens investig studi

D006528;D008113;D065626

T047;T191

36,333,805

pediatr tuberculosi outcom factor associ unfavor treatment outcom botswana retrospect analysi global amount research outcom pediatr tuberculosi tb disproportion less adult tb diagnosi paediatr tb also problemat develop countri aim studi describ outcom pediatr tb botswana identifi factor associ unfavor outcom

D015658;D014376

T047

36,333,803

reimburs expens medicin stakehold perspect sma medicin nusinersen dutch coverag lock polici reimburs expens medicin pose grow challeng healthcar worldwid order increas control cost medicin dutch govern introduc coverag lock cl polici cl postpon decis regard reimburs expens medicin detail advic ie cost effect given cl place six year rais mani question concern current evalu known author better understand effect cl stakehold involv may contribut reflect cl process help find way improv evalu dutch polici also relev countri aim optim reimburs procedur expens treatment perform evalu focus cl procedur medicin nusinersen nusinersen first treatment spinal muscular atrophi sma follow ema approv may place cl analysi cost effect ad therapeut valu result advic reimburs limit children younger year start treatment implement august onward

D009841;D009134

T047;T114

36,333,802

zero malaria mirag realiti popul sub saharan africa health transit global burden malaria continu signific public health concern despit advanc made therapeut malaria continu high morbid mortal associ infecti diseas sub saharan africa continu affect diseas unfortun region burden indig health system recent increas lifestyl diseas region current health transit complic situat pose doubl challeng alreadi ail health sector answer continu challeng malaria african union start zero malaria start campaign seek person malaria prevent bring grass root level review discuss contribut sub saharan africa whose popul health transit malaria elimin addit review explor challeng health system countri face may hinder attain zero malaria goal

D019456;D008288

T068;T047

36,333,800

attempt suicid pact covid era psychiatr perspect suicid pact joint activ induc death two individu essenti unavoid characterist mutual consent one partner domin relationship common male usual induc action case one activ carri undiagnos psychopatholog dimens patholog subthreshold trait found enter suicid agreement presenc cluster b person trait narcissist borderlin particular relev domin partner submiss one depend person trait frequent case similar health emerg covid pandem seem lead greater suicid includ suicid pact coupl whose motiv vari includ first financi problem strict follow fear infect abl return home abroad

D000086382;D013405

T033;T047;T067

36,333,799

metagenom proteom analysi bacteri ret communiti proteom profil degum process kenaf bast data microbi communiti function protein associ degum kenaf remain scant analyz microbi communiti associ kenaf hibiscus cannabinus bast fiber ret identifi potenti candid degum bacteria ret liquid collect analyz day day day evalu yield qualiti kenaf fiber differ ret time besid microbi communiti character use metagenom proteom analysi lc msms technolog

D031584

T002

36,333,797

posterior atlantoaxi intern fixat use harm techniqu assist base navig robot treatment atlantoaxi instabl evalu accuraci screw placement use tirobot surgic robot harm procedur assess clinic outcom techniqu

D001268;D013123;D012371;D007593;D013122

T061;T090;T030;T033;T047

36,333,796

occup risk variat nasopharyng cancer nordic countri aim studi estim occup risk variat incid nasopharyng cancer npc larg popul base cohort nordic occup cancer nocca studi

D009303;D016273;D009784

T047;T191;T037

36,333,795

associ renal function screen frequenc renal function declin patient type diabet real world studi primari health care examin associ screen frequenc estim glomerular filtrat rate egfr substanti reduct egfr among type diabet td patient normal egfr mlmin impair kidney function egfr mlmin

D003924;D003928;D051437

T047

36,333,794

identifi complex patient famili medicin potenti benefit case manag short questionnair deriv interm self assess imsa questionnair investig use interm self assess imsa questionnair compon identifi patient candid would benefit case manag cm general practic

D012647;D000071959

T055;T097;T041

36,333,793

prepar student deal consequ workforc shortag among health profession qualit approach healthcar face shortag qualifi healthcar profession pandem brought light fragil balanc affect healthcar system govern realiz system profession work need support differ level strengthen retent workforc health profession educ play import role ensur new generat worker sound person profession compet success face challeng profession practic challeng describ literatur extent consid health profession educ less clear

D006282;D003479

T065;T170;T097

36,333,792

genom landscap immun characterist prognost mutat signatur cervic cancer china studi aim analys genom alter profil immun characterist cohort chines cervic cancer patient understand certain patient benefit molecular target therapi immunotherapi well prognost signific

D002583;D002294;D000230

T191

36,333,791

micturit toilet compar bedpan labor nullipara random control trial bladder overdistens labor may lead prolong postpartum urinari retent hypothes nullipara mobil toilet like achiev satisfactori micturit

D000072296;D007743

T040;T074;T073

36,333,790

whole transcriptom profil chrysanthemum seticusp improv genom annot shed new light mrna mirna lncrna network ray floret disc floret chrysanthemum seticusp emerg model plant speci cultiv chrysanthemum especi studi involv diploid self compat pure line gojo genom sequenc assembl chromosom howev genom annot c seticusp still need improv elucid complex regulatori network speci

D062085;D035683;D031202

T123;T002;T114

36,333,789

optimis calophyllum inophyllum seed oil nanoemuls potenti wound heal agent effici deliveri system calophyllum inophyllum seed oil cso form nanoemuls optimis enhanc stabil ensur therapeut effici potenti agent various biomed applic

D029759

T002

36,333,788

itraq base proteom analysi deinococcus radioduran respons c heavi ion irradi deinococcus radioduran radioduran best known extrem resist divers environment stress factor includ ioniz radiat ir ultraviolet uv irradi oxid stress high temperatur robust dna repair system antioxid system demonstr contribut extrem resist radioduran howev practic studi mechan under radioduran extraordinari resist reli treat strain post treatment recoveri lag phase identifi key element involv direct gene protein chang radioduran stress yet character

D034301;D020450

T196;T007

36,333,787

tadmast comprehens web base tool analysi topolog associ domain chromosom conform captur deriv provid substanti genet data understand chromatin self organ techniqu identifi region high intrasequ interact call topolog associ domain tad tad structur function unit shape chromosom influenc genom express mani domain differ across cell develop impact diseas thus analysi identifi domain provid insight genom regul henc mani approach identifi domain across mani cell line despit avail multipl tool tad detect tad caller speed flexibl result inconsist reproduc remain challeng research area

D002843;D002875

T026;T116

36,333,786

fetuin allevi neuroinflamm traumat brain injuri induc microgli necroptosi regul nrf ho pathway microglia mediat inflammatori respons vital mechan secondari damag follow traumat brain injuri tbi under mechan microgli activ unclear

D000070642;D017628

T025;T037

36,333,785

courag care peopl think attitud toward adolesc contracept use among rwandan famili plan provid adult femal modern contracept user rwanda sexual activ unmarri young women use famili plan compar marri women adolesc import time growth develop often includ initi sexual activ sexual activ adolesc need support access contracept servic prevent negat health outcom sub saharan africa adolesc popul repres larg share total popul proport predict expand time adolesc contracept need larg unmet grow number increas potenti negat health sequela due low use contracept adolesc rwanda grow popul adolesc studi aim explor perspect famili plan provid adult modern contracept user adolesc contracept use inclus adult communiti member studi uniqu contribut research adolesc contracept use sub saharan africa reli primarili perspect adolesc famili plan provid

D005193;D003271

T033;T121;T058

36,333,784

lack causal associ heart failur osteoporosi mendelian random studi heart failur hf implic osteoporosi howev causal remain unestablish sought assess causal associ genet liabil hf osteoporosi use mendelian random mr analys

D010024;D006333

T047;T046

36,333,782

effect covid pandem mental health daili occup activ among health profession colombia nation studi covid pandem place unpreced physic mental burden healthcar worker frequent high risk infect particular low incom countri studi aim assess preval associ factor anxieti depress stress well chang daili occup activ among healthcar profession due covid pandem colombia

D000086382

T047;T067

36,333,780

age distractor resist work memori emot valenc matter emot stimuli use target work memori wm task moder age relat differ wm perform show age associ reduct negat bias phenomenon refer posit effect howev littl research whether emot distractor similar moder effect moreov under neural mechan effect studi studi examin behavior neurophysiolog basi age differ resist emot distractor within wm

D008570;D001288

T041

36,333,779

associ water sanit hygien access preval soil transmit helminth schistosom infect wolayita ethiopia geshiyaro project year intervent assess impact communiti school base water sanit hygien wash intervent reduc infect soil transmit helminth sth schistosom parasit combin deworm wolayita zone ethiopia

D060766;D006376;D006725;D012551;D006373

T047;T204;T167

36,333,778

stem cell phenotyp predict therapeut respons glioblastoma mgmt promot methyl grow bodi evid support presenc popul cell glioblastoma gbm stem cell like phenotyp share certain biolog marker adult neural stem cell includ express sox cd prom nes nestin studi design determin relationship express stem cell marker clinic outcom gbm patient quantifi intens express protein cd sox immunohistochemistri ihc cohort patient idh wildtyp gbm evalu patient outcom use kaplan meier cox proport hazard analysi patient mgmt promot methyl status age predictor overal surviv progress free surviv level sox cd associ outcom univari analysi howev stratif tumor base low high level cd sox express reveal mgmt methyl predictor progress free surviv overal surviv tumor high level express cd sox tumor low level express cd sox show relationship mgmt methyl surviv relationship mgmt stem cell marker confirm second patient cohort tcga dataset result show stratif gbm level express cd sox improv prognost power mgmt promot methyl status identifi low express group clinic outcom associ mgmt promot methyl status high express group outcom strong associ mgmt promot methyl status find support concept presenc high stem cell phenotyp gbm mark express sox cd may associ clinic respons treatment

D005909;D001932

T191

36,333,777

novel dual digest symbiosi scale nutrit immun system holobiont rimicari exoculata deep sea hydrotherm vent area depriv light anim reli chemosynthet symbiont nutrit symbiont may locat cuticl insid modifi organ special cell nonetheless mani anim open function digest tract vent shrimp rimicari exoculata fuel main gill chamber symbiont also complet digest system symbiont found shrimp foregut midgut role remain unknown use genom resolv metagenom separ foregut midgut sampl taken specimen live three contrast site along mid atlant ridg tag rainbow snake pit reveal genet potenti

D033364;D060086

T070;T204

36,333,776

macrophag polar toward phenotyp nf b signal patient behet diseas macrophag key innat immun cell implic pathogenesi behet diseas bd macrophag polar play pivot role inflammatori respons studi aim investig role bd serum phenotyp function macrophag polar

D016328;D001528

T129;T047;T116

36,333,775

contextu factor influenc implement new midwif educ programm india qualit studi indian govern commit educ midwiv accord intern norm goal critic midwiv provid evid base high qualiti midwiferi care need explor contextu factor influenc new midwiferi educ programm henc aim studi explor contextu factor influenc implement nation midwiferi educ programm midwiferi educ futur nurs practition midwiferi npms india qualit research design use data collect focus group discuss n total particip repres seven nation intern organis support indian govern midwiferi initi transcrib interview analys use content analysi studi contextu factor influenc implement new midwiferi educ programm india show organis administr process complex develop midwiferi educ nurs practition midwiferi need fast track educ educ futur midwiv india elsewher similar set could benefit effort simplifi organis administr process parallel mobil innov teach learn approach bridg theori practic

D008880;D009721

T091;T097

36,333,774

high grade desmoplast infantil astrocytoma year old child syndrom case report syndrom common chromosom abnorm human associ central nervous system tumor primari acut lymphoblast leukemia germinoma desmoplast infantil astrocytoma yet report syndrom desmoplast infantil astrocytoma rare intracrani tumor most occur first year life usual present larg aggress tumor solid cystic compon genet link braf mutat despit rapid growth pattern usual favor prognosi neurosurg excis presenc extrem rare genet link tumor combin syndrom common human genet defect make novel clinic present also rais research worthi question undiscov link two genet disord

D001254;D001932;D004314;D018303;D058627

T019;T047;T191

36,333,773

levonorgestrel releas intrauterin devic plus metformin megestrol acet plus metformin fertil spare treatment atyp endometri hyperplasia earli endometri carcinoma prospect random blind endpoint design trial protocol endometri adenocarcinoma ec fifth common cancer women worldwid standard treatment ec includ hysterectomi result loss reproduct function thus conserv treatment patient strong demand progestin therapi wide accept main fertil spare treatment young women endometri hyperplasia atypia eha well differenti endometrioid endometri cancer trial investig effect conserv treatment obes women earli stage ec

D004714;D007436;D008687;D016889

T121;T109;T191;T047;T074

36,333,772

singl cell profil cd spinal cord cell reveal microgli b cell heterogen crosstalk follow spinal cord injuri immun cell play crucial role spinal cord injuri sci howev incomplet knowledg immun contribut injuri repair hinder develop sci therapi leverag singl cell observ describ key popul immun cell present spinal cord chang transcript profil uninjur subacut chronic stage sci

D017628;D013119

T025;T037

36,333,771

stellat ganglion block reliev acut lung injuri induc sever acut pancreat via mir psocsjakstat axi acut lung injuri ali preval complic sever acut pancreat sap also lead contributor respiratori failur even death sap patient intend investig function mechan stellat ganglion block sgb amelior sap induc ali sap ali engin sap ali model rat treat sgb stain dri wet method implement evalu patholog alter tissu pulmonari edema rat serum chang profil tnf il il il examin profil mir p socsjakstat detect function assay perform confirm role mir p modul socsjakstat pathway pulmonari epitheli cell find reveal sgb vigor allevi sap rat lung tissu damag lung edema lessen generat pro inflammatori cytokin tnf il il sgb enhanc soc express hamper mir p suppress jakstat pathway activ evidenc mechan studi mir p target utr soc repress express henc result jakstat pathway activ anim trial discov sgb amelior sap ali boost soc express mitig level pro inflammatori factor mir p plasma vitro mir p overexpress substanti facilit pulmonari epitheli cell apoptosi inflamm jakstat pathway activ restrain soc express work hint sgb could modul mir psocsjakstat axi allevi sap ali

D010195;D055371;D011654;D035683

T123;T037;T114;T047;T046

36,333,770

preval manag chronic pain chines popul find china pain health index chronic pain common diseas peopl worldwid suffer compar research preval manag chronic pain develop countri relat lack research field china research aim construct china pain health index cphi evalu current status preval manag chronic pain chines popul

D059350

T184;T047

36,333,769

knee osteoarthr pre screen questionnair kop cross cultur adapt measur properti brazilian version kop brazilian version despit criteria alreadi establish classif knee osteoarthr oa radiograph andor clinic knee oa diagnosi usual occur case fulli manifest advanc diseas make health promot prevent function rehabilit advanc stage diseas less effect addit radiograph knee oa generat financi cost health servic therefor develop valid screen instrument assess probabl develop progress knee oa would great valu clinic practic scienc

D020370

T047

36,333,768

sever acut malnutrit recoveri rate still minimum standard predictor time recoveri among month old children healthcar set southwest ethiopia despit current avail scientif proven treatment nation guidelin sam recoveri rate still consider behind expect continu devast impact five children identifi predictor time recoveri might help reach minim criterion establish nation sphere decreas child mortal therefor current studi assess time recoveri predictor among children age month admit sam healthcar set southwest ethiopia

D000067011;D011014

T047;T050

36,333,766

longitudin phenotyp patient acut respiratori distress syndrom multi databas studi previous identifi phenotyp acut respiratori distress syndrom ard limit disregard tempor dynam aim identifi longitudin phenotyp ard test prognost predict enrich longitudin phenotyp develop simplifi model phenotyp identif

D012128

T047

36,333,764

effect lncrna mirhg modifi mscs exosom deliveri synergist attenu vein graft intim hyperplasia mesenchym stem cell mscs use repair tissu injuri howev treatment effect satisfactori investig whether lncrna mirhg could promot surviv migrat mscs oxid stress mimic vivo environ furthermor studi protect effect exosom secret mscs transfect mirhg endotheli cell studi aim determin whether exploit mscs exosom modifi lncrna mirhg would exert synergist therapeut effect attenu vein graft intim hyperplasia effect

D055354;D062085;D059630

T026;T123;T025;T114

36,333,763

quantit ct analysi predict esophag fistula patient advanc esophag cancer treat chemotherapi chemoradiotherapi esophag fistula one serious complic chemotherapi chemoradiotherapi crt advanc esophag cancer studi aim evalu perform quantit comput tomographi ct analysi establish practic imag model predict esophag fistula esophag cancer patient treat chemotherapi chemoradiotherapi

D004938;D004937

T191;T190

36,333,761

trem defici impair recoveri phagocytosi dysregul myeloid gene express virus induc demyelin trigger receptor express myeloid cell trem play protect role neurodegen diseas contrast trem function exacerb tissu damag respiratori viral liver infect therefor investig role trem viral encephalomyel model associ promin th mediat antivir immun lead demyelin

D001921;D003711

T023;T046;T047

36,333,759

health technolog assess support respons public health emerg public health emerg phes covid crisi threat global health public order recommend countri bolster phe respons invest health technolog assess hta defin systemat process gather pertin inform evalu health technolog medic econom social ethic standpoint present exampl hta organ low middl incom countri adapt support phe relat decis covid describ way hta help respons phe turn advoc hta capac develop global increas institut accept method build block prepared respons futur phes final long term potenti hta strengthen health system embed confid transpar scientif polici recogn

D013673;D000086382

T058;T067;T047

36,333,755

persian version psycholog flexibl sport scale psychometr studi grow bodi research suggest psycholog flexibl pf import psycholog construct relat psycholog health human perform psycholog flexibl sport scale pfss first general scale assess sport relat pf far pfss yet valid context sweden therefor current studi sought investig persian version pfss p pfss extend investig psychometr properti pfss iranian athlet

D013177

T056

36,333,754

microbi communiti associ parascari spp infect juvenil hors parasit nematod includ larg roundworm colloqui known ascarid affect health well livestock anim worldwid equin ascarid parascari spp import parasit juvenil hors first ascarid develop widespread anthelmint resist microbiota shown import factor fit mani organ includ parasit nematod endosymbiot wolbachia exploit treatment filariasi human

D001199;D017191;D006734;D064307

T032;T204;T028;T047;T001

36,333,753

role person trait leisur activ predict wellb young peopl relationship wellb person studi extens studi examin period adolesc emerg adulthood moreov influenc contextu factor engag leisur activ rare consid

D007899;D010551

T078;T056;T041

36,333,752

bifidobacteri carbohydratenucleosid metabol enhanc oxid phosphoryl white adipos tissu protect diet induc obes comparison gut microbiom lean obes human reveal obes associ gut microbiom plus chang numer environment factor includ high fat diet hfd report two speci bifidobacterium crucial control metabol paramet korean popul

D001644;D000069978

T007

36,333,751

effect earli stellat ganglion block cerebr vasospasm aneurysm subarachnoid hemorrhag block cvs studi protocol random control trial stellat ganglion block report expand cerebr vessel allevi vasospasm aneurysm subarachnoid hemorrhag howev causal relationship earli stellat ganglion block cerebr vasospasm prevent yet establish purpos studi explor effect safeti earli stellat ganglion block prevent treatment cerebr vasospasm delay cerebr ischemia

D020301;D013345;D002545

T047;T046

36,333,749

fit base risk stratif model effect screen colorect neoplasia earli onset colorect cancer chines popul nationwid multicent prospect studi fulli valid risk stratif strategi establish china colonoscopi resourc limit aim develop valid fecal immunochem test fit base risk stratif model colorect neoplasia cn individu recruit center nationwid random alloc deriv n valid cohort n multivari logist analys perform develop nation colorect polyp care ncpc score form risk stratif model along fit ncpc score develop eight independ predict factor divid three level low risk lr intermedi risk ir high risk hr individu ir hr ncpc score fit classifi increas risk individu risk stratif model recommend colonoscopi irhr ncpc score show higher preval cns vs p acn vs p lr also confirm valid cohort similar relat risk predict perform demonstr non specif gastrointestin symptom nsgs asymptomat cohort risk stratif model identifi cn acn crc guid individu receiv colonoscopi identifi earli onset acn earli onset crcs young individu receiv colonoscopi risk stratif model show good risk stratif abil cn earli onset crcs chines popul includ individu nsgs young age

D055088;D015179

T060;T058;T191

36,333,747

mitochondri protect effect caus administr mefenam acid sepsi pathophysiolog sepsi may involv activ nod type receptor contain pyrin domain nlpr mitochondri oxid damag one primari essenti oxid product oxoguanin oxog accumul mitochondri dna mtdna induc cell dysfunct death lead hypothesi mtdna integr crucial maintain neuron function sepsi sepsi modul nlrp activ critic mefenam acid mfa potent drug reduc inflammasom activ attenu acut cerebr inflammatori process thus studi aim evalu administr mfa implic reduct inflammatori paramet mitochondri damag anim submit polymicrobi sepsi test hypothesi adult male wistar rat submit cecal ligat perfor clp model sepsi induct receiv inject mfa dose mgkg steril salin mlkg h sepsi induct frontal cortex hippocampus dissect analyz level tnf il il oxid damag thiobarbitur acid reactiv substanc tbar carbonyl dcf da oxid paramet protein express mitochondri transcript factor tfam nlrp oxog bax bcl ioniz calcium bind adaptor molecul iba activ mitochondri respiratori chain complex observ septic group structur studi show increas proinflammatori cytokin mediat increas activ nlrp signific oxid damag higher product reactiv oxygen speci ros mitochondria damag mtdna also observ increas oxog level lower level tfam ngf addit group increas pro apoptot protein iba posit cell howev mfa dose mgkg decreas inflammasom activ reduc level cytokin oxid damag increas bioenerget efficaci reduc product ros oxog increas level tfam ngf bcl reduc microgli activ result suggest mfa induc protect central nervous system earli onset sepsi

D008528;D018805

T121;T047;T046;T109

36,333,745

bodi stuf apprehens result distal esophag impact case report review literatur bodi stuf bodi pack two method conceal illicit drug bodi stuf defin oral ingest illicit drug typic avoid law enforc detect consequ possess may present serious medic emerg patient common bodi stuffer ingest possibl larg unknown quantiti illicit substanc avoid detect drug apprehens ingest typic hasti impuls therefor substanc ingest rare packag way would consid safe ingest

D000075066;D005547;D013287

T016;T109;T131;T020;T037;T054;T072

36,333,744

effect day storag differ temperatur detect felin kidney injuri molecul urin human kidney injuri molecul kim biomark acut kidney injuri quantifi urin preliminari investig cat experiment induc acut kidney injuri show kim urin concentr correl kidney injuri histopatholog score later flow assay lfa recent becom avail patient side felin kim measur vitro paramet assay yet determin object studi determin detect kim urin store differ temperatur time establish linear rang lfa assess intra assay repeat measur result ten urin sampl rang kim concentr store room temperatur c c c test lfa day concentr kim sampl signific differ day valu except one sampl store day room temperatur yield signific higher valu assay result correl coeffici mean coeffici variat sampl slope curv expect versus measur valu sampl dilut two fold nine time result linear dilut

D058186;D002371

T047;T037

36,333,742

music famili interact mufasa protocol articl rct studi general mental health interperson skill famili crucial children develop futur research suggest link particip music activ individu sens mental health well effect object measur health qualiti life social skill rehabilit various kind howev denmark mani servic famili school age children year focus prevent strengthen famili interact herebi minimis risk children thrive develop optim term social emot skill compet purpos studi investig effect share music activ famili interact parent stress child well

D009146;D009147

T061;T170

36,333,741

pilot studi evalu semi rigid flexibl cathet less invas surfact administr preterm infant respiratori distress syndrom random control trial respiratori distress syndrom mani neonatolog center worldwid perform minim invas surfact applic prematur infant use small diamet cathet endotrach intub surfact administr

D011663;D012127

T123;T047;T121;T109

36,333,740

impact suboptim inappropri treatment healthcar resourc use cost among patient uncompl urinari tract infect analysi integr deliveri network electron health record although uncompl urinari tract infect uuti occur femal patient without urolog abnorm histori urolog procedur complic comorbid one common communiti infect unit state us limit data avail concern associ antibiot resist suboptim prescrib econom burden uuti examin preval suboptim antibiot prescrib antibiot resist effect healthcar resourc use cost

D057286;D014552

T047;T170;T073

36,333,739

intermitt prevent treatment malaria amongst pregnant women give birth centr hospitali rgional paul moukambi de koula moutou southeastern gabon evalu malaria control strategi pregnant women essenti object studi determin factor influenc antenat care anc visit attend complet intermitt prevent treatment sulfadoxin pyrimethamin iptp sp impact health pregnant women newborn babi live semi urban rural area southeastern gabon

D015597;D000962;D008288

T121;T047

36,333,738

viral communiti wide auxiliari metabol gene differ lifestyl habitat host viral encod auxiliari metabol gene amg import toolkit modul host metabol microbi driven biogeochem cycl although function amg extens report numer environ still know littl driver shape viral communiti wide amg composit natur ecosystem explor driver viral communiti wide amg composit critic deeper understand complex interplay among virus host environ

D001435;D014780

T005

36,333,737

loss brca trp adult mous mammari ductal epithelium result develop hormon receptor posit hormon receptor negat tumor depend inactiv rb famili protein breast cancer heterogen diseas sever histolog molecular subtyp model repres subtyp essenti translat research aim improv clinic strategi target therapeut

D042361;D001943;D015674

T023;T191;T024

36,333,736

sex age differ associ fatti liver index defin non alcohol fatti liver diseas cardiometabol risk factor cross section studi despit extens scientif evid accumul epidemiolog risk factor non alcohol fatti liver diseas nafld evid explor sex age relat differ remain insuffici present cross section studi aim investig possibl sex differ preval fli defin nafld well associ common risk factor across differ age group larg sampl spanish work adult

D065626;D003920;D006973;D002318

T047

36,333,735

infant congenit heart defect proteinuria case report branchio oto renal bor syndrom rare autosom disord wide varieti clinic manifest high degre heterogen typic clinic manifest bor syndrom includ deaf preauricular fistula abnorm gill slit renal malform howev atyp phenotyp congenit hip dysplasia congenit heart anomali facial nerv paresi rare bor syndrom might easili misdiagnos congenit disord

D019280;D006330

T019;T047

36,333,733

develop psychometr assess sexual reproduct health profil women type diabet mellitus improv sexual reproduct health srh women type diabet mellitus tdm plan formul basi exist situat situat examin valid tool conform specif domain srh target group present studi seek develop assess psychometr properti srh profil women tdm

D003922;D000074384

T047;T032

36,333,730

diagnosi tuberculosi autoimmun hepat system lupus erythematosus overlap syndrom case report ampl evid indic immunosuppress therapi immun dysregul system lupus erythematosus increas risk tuberculosi interest case report suggest tuberculosi could also risk factor system lupus erythematosus autoimmun diseas

D019693;D008180;D014376

T047

36,333,729

safeti efficaci corticosteroid ard patient systemat review meta analysi rct data acut respiratori distress syndrom ard acut critic diseas among children adult previous studi shown administr corticosteroid remain controversi therefor meta analysi random control trial rcts perform evalu safeti efficaci corticosteroid

D006854;D012128

T125;T121;T047;T109

36,333,727

implement coach mclung sm primari care use cluster random step wedg trial design asthma preval chronic diseas difficult manag associ mark dispar outcom one promis approach address dispar share decis make sdm method patient provid cooper make decis asthma care sdm associ improv outcom patient howev time constraint staff avail note implement barrier use health inform technolog solut may facilit util sdm coach mclung sm collabor web base applic involv pediatr patient caregiv provid person experi gather patient report data background logic provid decis support audienc develop well inform treatment plan togeth goal studi evalu implement coach mclung sm intervent primari care

D000080536;D001249

T047;T041

36,333,725

olfactori marker protein contain leucin rich domain loop import nuclear export olfactori marker protein omp cytosol protein express matur olfactori receptor neuron orn omp modul camp signal regul olfactori sensat axon target omp small solubl protein passiv diffus nucleus cytoplasm expect howev omp most situat cytosol spars detect nuclei subset orn hypothalam neuron heterolog omp express cultur cell omp enter nucleus associ transcript factor howev omp retain cytosol rest unclear omp propos affect cell differenti import understand omp distribut cytoplasm nucleus elucid structur profil omp appli sever bioinformat method multipl sequenc align msa omp protein sequenc rank evolutionarili conserv residu addit previous report camp bind domain identifi leucin rich domain loop omp introduc mutat leucin rich region heterolog express mutant omp hekt cell mutat alanin increas nuclear distribut omp quantifi immunocytochemistri western blot therefor conclud omp contain leucin rich domain import nuclear transport

D018034

T026;T025

36,333,724

electroacupunctur effect therapi tapia syndrom transor intub general anesthesia case report review literatur tapia syndrom rare complic airway manipul general anesthesia injuri vagus nerv x hypogloss nerv xii transor intub primari caus diseas typic symptom includ hoars dysarthria dysphagia tongu muscl atrophi tongu deviat toward affect side report case tapia syndrom treat electroacupunctur acceler recoveri process discuss potenti mechan behind find base previous research

D015671;D020437

T061;T047

36,333,723

preval malaria risk factor lake tana surround area northwest ethiopia ethiopia malaria major concern health socio econom develop countri occurr peak agricultur activ factor environment human host parasit vector determin malaria transmiss therefor present studi conduct determin preval associ factor malaria among febril patient visit select health centr

D008288;D016778;D016780

T047

36,333,720

acut effect niv peripher muscl function aerob perform patient chronic obstruct pulmonari diseas pilot studi non invas ventil niv reduc respiratori load demand peripher muscl

D063087;D029424

T061;T047

36,333,719

mg relat lncrnas predict prognosi regul immun microenviron lung squamous cell carcinoma n methylguanosin mg long non code rnas lncrnas wide studi cancer found use assess tumor progress howev role mg relat lncrnas lung squamous cell carcinoma lusc remain unclear thus crucial identifi mg associ lncrnas definit prognost valu studi aim investig prognost valu correl tumor mutat burden impact tumor immun microenviron mg relat lncrnas lusc method lusc transcriptom data clinic data download cancer genom atlas mg relat lncrna mrna co express network construct use pearson correl analysi cox regress analys use determin risk model mg associ lncrnas prognost valu risk signatur verifi use kaplan meier method receiv oper characterist curv analysi princip compon analysi nomogram base risk score clinic characterist develop gene set enrich analysi use function annot analyz risk signatur associ among risk signatur tumor mutat burden tumor infiltr immun cell analyz rt qpcr use investig express mg relat lncrnas lusc cell cytolog function srp verifi wound heal assay transwel assay

D062085;D008175;D002294;D002289

T123;T191;T114

36,333,718

studi protocol glow studi maximis treatment option recurr glioblastoma patient whole genom sequenc base diagnost prospect multicent cohort studi glioblastoma gbm common glial primari brain tumour without except lethal everi year approxim patient diagnos heterogen diseas netherland despit neurosurgeri chemo radiat therapi tumour inevit recur current gold standard time recurr treatment option limit unfortun result dedic trial new drug disappoint goal project obtain evid chang standard care soc procedur includ whole genom sequenc wgs consequ adapt care guidelin specif patient group poor prognosi offer optim time benefit novel therapi even absenc tradit registr trial small volum cancer indic

D005909;D001932

T191

36,333,717

communiti social capit health relat qualiti life among empti nest elder western china moder effect live arrang present empti nest phenomenon becom serious world especi china health problem deserv attent therefor purpos studi explor impact communiti social capit health relat qualiti life empti nest elder

D011788;D066270

T078;T169

36,333,716

examin variat implement intervent address stillbirth nation subnat level experi uganda current global burden stillbirth disproportion affect region sub saharan africa uganda locat respond burden polici made nation level diffus centr translat servic deliveri district level charg implement decentr health servic arrang variat emerg whenev polici recommend move nation subnat level aspect often lost along way tool avail facilit knowledg determin polici innov implement within healthcar system howev extent appli explain variat implement intervent address stillbirth reduct uganda remain scant aim articl examin variat implement intervent address stillbirth nation subnat level uganda use consolid framework implement research cfir

D050497;D003695

T033;T058;T093

36,333,715

accuraci thorac pedicl screw placement adolesc idiopath scoliosi patient use entri point identifi new landmark comput tomographi studi although thorac pedicl tp screw gain increas popular surgic treatment adolesc idiopath scoliosi ai patient question remain accur select entri point tp screw placement patient main object present studi evalu accuraci tp screw placement ai patient use entri point identifi new landmark

D012600;D065289;D013123;D007738

T061;T047;T074;T190

36,333,714

covert contracept use amongst urban poor accra ghana experi health provid estim one third women ghana use contracept without knowledg partner phenomenon known covert contracept use ccu research ccu date focus individu women neglect role health system studi explor ccu urban poor communiti accra ghana experi perspect health provid

D003270;D006282

T121;T039;T097

36,333,713

childhood immun age appropri vaccin indonesia childhood immun cost effect way protect individu communic diseas howev although larg literatur childhood immun indonesia pauciti research age appropri measl dtwp vaccin inequ immun coverag across indonesia

D017589;D008457

T058;T047

36,333,712

associ social integr particip product loss among person chronic pain registri base cross section studi examin associ factor social inclus particip product loss employ person chronic pain assess interprofession pain rehabilit programm hypothes factor social inclus particip work relat social factor signific associ product experienc chronic pain expect moder effect

D059350

T184;T047

36,333,710

two year effect erenumab resist chronic migrain prospect real world analysi control real world evid demonstr efficaci calcitonin gene relat peptid cgrp monoclon antibodi mab migrain howev data one year sustain effect cgrp mab resist chronic migrain cm spars method two year real world prospect analysi ongo singl centr audit conduct patient resist cm patient receiv month erenumab six month assess effect respond consid achiev least reduct month migrain day mmd month compar baselin secondari outcom also analys includ chang headach impact test version hit

D000077221;D008881

T121;T047

36,333,709

plant sex affect plant microbiom assembl dioecious populus cathayana tree differ soil nitrogen condit dioecious plant coevolv divers plant microbiom crucial fit product host sexual dimorph morpholog physiolog gene express may relat differ microbi composit affect male femal fit differ environ howev sex specif impact ecolog process control microbiom assembl well known studi populus cathayana male femal plant differ nitrogen condit hypothes male femal differ affect bacteri fungal communiti rhizospher soil root old leav young leav physiolog trait transcriptom profil male femal plant investig reveal potenti mechan control microbiom assembl

D032107;D064307

T001;T032;T028;T002

36,333,708

preliminari experi obliqu occlus techniqu robot assist infrahepat inferior vena cava thrombectomi step step procedur short term outcom aim compar oncolog outcom obliqu occlus techniqu tradit techniqu robot assist radic nephrectomi rarn inferior vena cava ivc thrombectomi explor safeti effect obliqu occlus techniqu

D002292;D007680;D012371;D020246

T090;T047;T191;T046

36,333,707

primari care util patient newli diagnos cancer covid pandem popul base studi covid pandem great impact primari care cancer care studi primari care util ontario canada chang patient newli diagnos cancer prior covid pandem compar diagnos non pandem year

D000086382;D009369

T047;T191;T067

36,333,705

neonat heavi metal level associ sever neonat respiratori distress syndrom case control studi case control studi aim compar lead pb cadmium cd arsenic level neonat respiratori distress syndrom nrds level normal neonat test associ sever nrds indic level serum surfact protein sp cord blood cardiac troponin ctni high sensit c reactiv protein hs crp

D001151;D019216;D012127

T121;T196;T131;T047

36,333,704

budget impact analysi subcutan infliximab ct p sc treat inflammatori bowel diseas big european e countri european medicin agenc approv infliximab subcutan sc treatment inflammatori bowel diseas new mode infliximab administr reduc outpati visit cost intraven iv administr articl describ budget impact analysi introduc infliximab sc big european e market germani franc itali spain uk year healthcar payer perspect

D000911;D015212

T129;T047;T116

36,333,702

heterogen earli ill cours korean patient bipolar disord replic stage model clinic stage bipolar disord bd requir applic real world data next step hypothesi studi use stage model analyz long term cours bd korean patient base clinic featur treatment respons map progress bipolar ill earli phase onset ill

D001714;D009771

T048

36,333,701

presenc plasmodium malaria plasmodium knowlesi near malaria elimin set western indonesia indonesia progress toward malaria elimin achiev goal intervent measur must address cover plasmodium speci comprehens control measur surveil programm must intensifi studi aim determin preval microscop submicroscop malaria langkat district north sumatera provinc indonesia

D016790;D008288

T047;T204

36,333,700

identif express purif dna cytosin methyltransferas short recognit sequenc dna methyltransferas mtase enzym induc methyl one repres epigenet modif dna also use tool analyz epigenom howev regard dna cytosin methyl mtase identifi far drawback recognit sequenc overlap intrins dna methyl mammalian cell andor recognit sequenc long fine epigenet map identifi mtase short recognit sequenc never overlap cg dinucleotid systemat investig candid enzym identifi use databas search show high similar known cytosin mtase recogn short sequenc

D015254;D019175

T126;T116;T044

36,333,699

applic logist differenti equat model earli warn infecti diseas jilin provinc still relat serious diseas burden infecti diseas warn time differ infecti diseas implement intervent import logist differenti equat model use predict earli warn infecti diseas aim studi compar diseas fit effect logist differenti equat lde model general logist differenti equat glde model first time use data multipl infecti diseas jilin provinc calcul earli warn signal differ type infecti diseas use two model jilin provinc solv diseas earli warn schedul jilin provinc throughout year

D003141;D009107;D012541;D058872

T047;T067

36,333,698

must cut long stink thing uncov live experi uncircumcis pokot women north eastern uganda femal circumcis remain domin practic among pokot north eastern uganda paper explor live experi uncircumcis pokot women continu live communiti practic cherish

D002944;D012749;D015658

T061;T047

36,333,697

childhood maltreat suicid ideat chines children adolesc mediat role mind childhood maltreat cm associ suicid ideat si children adolesc yet mediat role mind associ remain unclear studi aim test mediat mind cm si associ among larg sampl chines children adolesc

D064866;D002649

T041;T048

36,333,696

toddler unusu sever polyarticular arthriti lung involv case report copa syndrom rare hereditari inflammatori diseas caus mutat gene encod coatom protein subunit alpha caus excess product type interferon case remind general paediatrician highlight relev associ arthriti lung involv toddler

D001171;D017563

T047

36,333,695

increas diaphragm echodens correl postop pulmonari complic patient major abdomin surgeri prospect observ studi associ increas morbid mortal postop pulmonari complic ppcs often occur major abdomin surgeri diaphragmat dysfunct suggest play import role develop ppcs diaphragm echodens use indic diaphragm function studi aim determin whether diaphragm echodens could predict occurr ppcs patient major abdomin surgeri

D003964;D000005

T023;T029

36,333,694

three dimension microenviron regul gene express function tight junction dynam ipsc deriv blood brain barrier microvessel blood brain barrier bbb play pivot role brain health diseas bbb brain microvascular endotheli cell bmec connect tight junction regul paracellular transport express special transport system regul transcellular transport howev exist vitro model bbb display variabl accuraci across wide rang characterist includ geneprotein express barrier function use isogen famili fluoresc label ipsc deriv bmec like cell ibmec brain pericyt like cell ipc within two dimension confluent monolay three dimension tissu engin microvessel explor microenviron regul gene express function vitro bbb show microenviron shear stress cell ecm interact cylindr geometri increas bbb phenotyp endotheli ident alter angiogen cytokin respons synergi pericyt co cultur tissu engin microvessel incorpor junction label ibmec enabl studi real time dynam tight junction homeostasi respons physic chemic perturb

D001812;D057026

T023;T025

36,333,693

long term evalu safeti biolog effect korean red ginseng panax ginseng long term vivo studi although korean red ginseng krg safe find evalu mo long studi safeti verifi mo krg administr clinic studi long term studi beyond mo insuffici studi investig safeti efficaci mo krg administr

D005894

T002

36,333,692

effect vitamin supplement sever stress urinari incontin premenopaus women vitamin insuffici random control clinic trial urinari incontin especi stress urinari incontin sui one problem experienc premenopaus women given role vitamin enhanc muscl strength function studi explor effect vitamin supplement sui premenopaus women

D014550;D014549;D014808

T047;T046

36,333,691

explor knowledg parent caregiv cancer symptom children observ studi regard need educ tool health promot low middl incom countri although case childhood cancer unlik prevent today standard children cancer cure howev dispar surviv exist among countri mexico overal surviv childhood cancer diagnos advanc stage therefor parent caregiv must optim knowledg earli sign symptom childhood malign larg non specif studi design explor current knowledg childhood cancer among parent caregiv mexico identifi need educ health promot low middl incom countri

D017028;D009369

T099;T098;T191;T097

36,333,690

surveil tobacco use among young adolesc trend predictor across three year souss tunisia develop countri overal decreas tobacco use last decad tunisia nation strategi reduc tobacco use set sinc howev strategi rare evalu object current studi examin trend tobacco use among middl schoolchildren governor souss tunisia determin predictor experiment

D012907;D064424

T055

36,333,689

pathway ovarian cancer diagnosi qualit studi ovarian cancer often diagnos late stage surviv poor qualit narrat patient pathway ovarian cancer diagnos may identifi opportun earlier cancer detect consequ earlier stage diagnosi

D055088;D010051

T060;T058;T191

36,333,688

associ serum vitamin level viscer adipos tissu among adolesc cross section observ studi nhane recent year obes vitamin defici preval among adolesc improv knowledg link vitamin viscer adipos tissu vat essenti health adolesc studi aim examin connect serum vitamin level vat mass among adolesc particip unit state

D050152;D014808

T047;T024

36,333,687

effect tracheal tube cuff inflat alkalin lidocain versus air hemodynam respons extub post oper airway morbid children prospect observ cohort studi ethiopia endotrach tube inflat cuff use manag maintain airway general anesthesia children later pressur exert inflat endotrach tube cuff tracheal mucosa exceed capillari perfus pressur patient may complain cough sore throat hoars postop period studi aim assess effect tracheal tube cuff fill alkalin lidocain versus air hemodynam paramet chang extub post oper airway morbid children

D008012;D010612

T121;T047;T184;T109

36,333,686

evalu chang negat posttrauma cognit mechan ptsd sever chang two separ intens treatment program veteran wealth evid illustr reduct negat posttrauma cognit npcs predict improv posttraumat stress disord ptsd symptom treatment yet specif tempor arrang chang construct less well understood studi examin tempor associ npc chang ptsd symptom chang two distinct intens ptsd treatment sampl

D014728;D013313

T098;T048

36,333,684

construct novel cuproptosi relat gene signatur predict prognosi estim tumor immun microenviron status papillari thyroid carcinoma cuproptosi new form program cell death recent report close relat tumor progress howev signific cuproptosi relat gene crgs papillari thyroid carcinoma ptc still unclear therefor studi aim investig role crg signatur prognosi predict immunotherapeut effect estim patient ptc

D015972;D013964

T045;T191

36,333,683

whether surgic resect biopsi make differ singl lesion primari central nervous system lymphoma singl center retrospect cohort studi primari central nervous system lymphoma pcnsl rare aggress diseas role surgic resect pcnsl alway center debat investig clinic follow data singl lesion pcnsl oper center focus comparison surgic resect biopsi

D016543;D008223

T191

36,333,682

point care c reactiv protein test result acut infect children primari care observ studi acut infect common reason children consult primari care serious infect rare differenti self limit ill remain challeng lead inappropri antibiot prescrib point care c reactiv protein test use guid antibiot prescrib adult howev children use remain unclear purpos studi assess point care crp test level respect patient characterist care set preliminari diagnosi manag

D007239;D011014

T047;T046;T050

36,333,681

covid impact psycholog health latinx transgend non binari individu mainland unit state puerto rico mix method studi covid pandem continu generat unpreced impact aspect everyday life across world howev histor current margin ident ie gender ethnic alreadi experi wide rang structur inequ disproport impact ltnb particular risk popul lie intersect raceethn gender ident languag migrat status geograph locat among other could increas covid health relat risk dispar object studi examin impact key social determin health ie gender ident countri health insur employ among sampl ltnb individu

D000086382;D063106

T047;T098;T067

36,333,680

phase ii studi carboplatin etoposid plus durvalumab previous untreat extens stage small cell lung cancer es sclc patient poor perform status ps neja studi protocol small cell lung cancer sclc account lung cancer limit prognosi approxim one third sclc patient poor perform status ps patient extens stage es sclc poor ps poor prognosi popul overal surviv carboplatin etoposid treatment month treatment develop unmet medic need recent combin anti pd l ligand program cell death antibodi platinum base chemotherapi becom standard care es sclc patient good ps ps hypothes combin anti pd l antibodi durvalumab carboplatin etoposid would feasibl effect patient

D055752;D008175

T191