PMID int64 35.7M 36.4M | Title/Abstract stringlengths 22 8.78k | MeshTerms stringlengths 7 101 | SemanticTypes stringlengths 4 64 |
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36,227,068 | chip monolith integr multimod carbon nanotub sensor gas chromatographi detector carbon nanotub cnt base chemiresistor promis gas detector gas chromatographi gc due intrins nanoscal poros excel electr conduct howev fabric reproduc long desorpt time limit sensit low dynam rang limit usag real applic paper report novel chip monolith integr multimod cnt sensor micro electro mechan system base bulk acoust wave baw reson embed underneath cnt chemiresistor devic fabric repeat improv site monitor cnt deposit use baw found acoust stimul acceler gas desorpt rate cnt surfac solv slow desorpt issu due differ sens mechan multimod cnt sensor provid complementari respons target improv sensit dynam rang compar singl mode detector prototyp chromatograph system use multimod cnt sensor prepar dedic design connect devic separ column gc system use quantit identif gas mixtur differ gc condit prove feasibl multimod cnt detector chromatograph analysi develop cmos compat multimod cnt sensor offer high sens perform miniatur size low power consumpt critic develop portabl gc | D037742;D055617 | T068;T104;T170;T073 |
36,227,062 | natur languag process radiolog request report chest imag compar five transform model multilabel classif proof concept studi radiolog request report contain valuabl inform diagnost find indic transform base languag model promis accur text classif | D000086382;D011871 | T047;T091;T067 |
36,227,061 | heat puls desorpt low volatil compound heat n gas puls mass spectrometri thermal desorpt low volatil compound rapid heat follow instant cool desir suppress thermal decomposit work new thermal desorpt method heat puls desorpt hpd develop heat n gas puls c ms direct solid sampl surfac desorb analyt ioniz dc corona discharg mass analyz orbitrap mass spectromet heat transfer heat n gas solid surfac effici desorpt solid sampl occur certain temperatur reach c short self control desorpt depend volatil analyt exit copper tube gas blow separ sampl surfac carryov occur enabl repetit analysi sampl hpd appli various compound narcot pharmaceut tablet explos analysi complet within second per sampl method high use quick consecut analysi real sampl potenti util food qualiti control counterfeit drug analysi detect explos safeti secur | D006358;D053834 | T120;T070 |
36,227,058 | modular assembl mxene framework noninvas diseas diagnosi via urinari volatil volatil organ compound voc urin valuabl biomark noninvas diseas diagnosi herein facil coordin driven modular assembl strategi use develop librari gas sens materi base porous mxene framework mfs take advantag modul divers composit tunabl structur mfs base librari provid choic satisfi gas sens demand meanwhil laser induc graphen interdigit electrod array microchamb laser engrav assembl microchamb host mf mhmf e nose mhmf e nose possess high discrimin pattern recognit simultan sens distinguish complex voc furthermor mhmf e nose plug play modul point care test poct platform modular assembl wireless real time monitor urinari volatil clinic sampl virtu machin learn poct platform achiev noninvas diagnosi multipl diseas high accuraci provid favor opportun earli diseas diagnosi diseas cours monitor relev research | D055549;D006108;D000080745 | T109;T196;T073 |
36,227,013 | systemat review meta analysi clinic outcom patient undergo chronic total occlus percutan coronari intervent chronic total occlus cto percutan coronari intervent pci improv patient symptom remain controversi whether impact subsequ clinic outcom | D054059;D062645;D009203 | T061;T047 |
36,227,012 | singl center experi aortic coarctat stent adult patient endovascular repair aortic coarctat coa becom import tool treatment expand patient popul studi present year experi endovascular repair coa | D001017;D019917;D057510 | T061;T047;T019 |
36,227,011 | novel model predict year mortal elect transfemor aortic valv replac tavr risk score aim develop valid effect predict model year mortal risk elect transfemor transcathet aortic valv replac tavr ie tavr risk tari model | D065467;D001024 | T061;T047 |
36,227,002 | ros respons biomimet nano platform enhanc chemo photodynam immunotherapi efficaci due complex bloodstream compon tumor microenviron tumor heterogen tradit nanoparticl limit effect low drug deliveri effici poor penetr deeper tumor erad tumor solv challeng novel platelet membran coat nanoparticl pcdd nps construct combin chemo photodynam immunotherapi melanoma platelet membran impart pcdd nanoparticl excel long circul effect tumor target abil solv issu low drug deliveri effici reach tumor cell releas drug load cdd micell becom posit charg facilit deep penetr tumor cytotox apoptosi experi show pcdd nanoparticl strongest tumor cell kill abil base excel result vitro pcdd use assess anti tumor distal tumor inhibit rat model result reveal pcdd combin pdt immunotherapi chemotherapi could inhibit primari tumor growth inhibit rate also suppress distant tumor growth inhibit rate lung metastasi far effect compar commerci taxoter explor molecular mechan show vivo immun respons induc increas posit immun respond suppress negat immun suppressor establish inflammatori tumor immun environ lead excel result tumor suppress lung metastasi conclus novel multifunct pcdd nanoparticl promis platform tumor combin chemotherapi photodynam therapi pdt immunotherapi | D010778;D053758;D008175;D000072317 | T073;T061;T131;T191;T121;T109 |
36,226,996 | artifici cell past present futur artifici cell construct imit natur cell allow research explor biolog process origin life construct method artifici cell top bottom approach achiev great progress past decad present comprehens overview develop artifici cell properti applic artifici cell deriv lipid polym lipidpolym hybrid natur cell membran colloidosom metal organ framework coacerv endow various function incorpor protein gene cell surfac encapsul insid cell modul determin properti artifici cell includ produc energi cell growth morpholog chang divis transmembran transport environment respons motil chemotaxi multipl applic artifici cell discuss focus therapeut applic artifici cell use carrier materi inform exchang shown function target deliveri system person drug addit artifici cell function substitut cell impair function enzym therapi immunotherapi use artifici cell intens focus research final prospect futur develop cell mimic properti broader applic highlight | D058045;D000073396 | T075;T109;T073 |
36,226,992 | genom character antimicrobi suscept dromedari associ staphylococcacea horn africa member staphylococcacea famili particular genus staphylococcus encompass import human anim pathogen collect character staphylococcacea strain appar healthi diseas camel n cattl n somalia kenya phenotyp character strain includ antimicrobi inhibitori concentr sequenc genom use long read sequenc close genom subsequ compar map virul resist associ gene pool genom base phylogenet reveal known staphylococcacea least two novel speci east african strain differ speci encompass novel sequenc type phylogenet distant clade one third strain non wild type mic resist least one follow antimicrobi tetracyclin benzylpenicillin oxacillin erythromycin clindamycin trimethoprim gentamicin streptomycin encod tet k blaz blaarl meca meca msra mphc sala dfrg aaca aphd str respect identifi first methicillin multidrug resist camel epidermidi strain sequenc type st east africa pool virul encod gene largest aureus strain expect although rather commens strain contain distinct virul encod gene identifi toxin antitoxin ta system hicahicb abieiiabiei famili report first time certain speci staphylococcacea strain contain least one intact prophag sequenc main belong siphovirida famili pinpoint potenti horizont gene transfer camel cattl strain also across distinct staphylococcacea clade speci import camel high valu crucial livestock speci arid semiarid region africa gain import give impact climat chang tradit livestock speci current knowledg respect staphylococcacea infect camel limit compar livestock speci better knowledg foster develop specif diagnost assay guid promis antimicrobi treatment option inform potenti zoonot risk character staphylococcacea strain isol camel respect antimicrobi resist virul trait detect potenti novel staphylococcus speci resist differ class antimicrobi first camel multidrug resist epidermidi strain sequenc type | D013203;D055624 | T007;T047 |
36,226,989 | n heterocycl carben catalys homoenol addit reaction cyano imino h chromen synthesi c function amino cyano h chromen diastereoselect n heterocycl carben catalys reaction enal cyano imino h chromen describ access new type c function amino cyano h chromen wide varieti enal iminochromen afford desir homoenol addit product amino h chromen good yield moder good diastereoselect | D001578;D008697 | T109 |
36,226,986 | hepat b virus core protein requir coval close circular dna transcript regul hepat b virus hbv infect major health burden worldwid current cure persist hbv coval close circular dna cccdna major obstacl antivir trement hbv core protein hbc emerg promis antivir target play import role critic step viral life cycl howev whether hbc could regul hbv cccdna transcript remain debat studi differ approach use address question synthes hbv cccdna hbvcircl transfect assay lack hbc show effect transcript hbv rna well hbv surfac antigen hbsag product hepatoma cell line primari human hepatocyt reconstitut hbc alter express cccdna deriv hbv marker similar result obtain vivo mous model harbor cccdna chromatin immunoprecipit chip chip sequenc assay reveal transcript regul hbc defici cccdna chromatin similar wild type cccdna furthermor treatment capsid assembl modul cam dramat reduc extracellular hbv dna could alter viral rna hbsag result demonstr hbc neither affect histon modif transcript factor bind cccdna direct influenc cccdna transcript although cam could reduc hbc bind cccdna suppress cccdna transcript activ thus therapeut target capsid hbc expect suffici reduc cccdna transcript import hepat b virus hbv core protein hbc emerg promis antivir target howev whether hbc regul hbv coval close circular dna cccdna transcript remain elus studi illustr hbc effect epigenet regul cccdna particip cccdna transcript given hbc dispens cccdna transcript novel cccdna target therapeut need hbv cure | D004270;D006509 | T047;T123;T114 |
36,226,985 | level influenza virus defect viral genom determin pathogenesi balbc mous model defect viral genom dvgs generat viral polymeras error rna replic trigger innat immun implic alter clinic outcom infect investig impact dvgs innat immun pathogen balbc mous model influenza virus infect generat stock influenza virus contain intern gene hn virus contain differ level dvgs indic differ genom pfu ratio lung epitheli cell high dvg stock immunostimulatori earli time point postinfect dvgs amplifi virus replic myeloid immun cell trigger proinflammatori cytokin product mous model infect differ virus stock produc diverg outcom high dvg stock induc earli type interferon ifn respons limit viral replic lung result minim weight loss contrast virus stock low level dvgs replic high titer amplifi dvgs time result elev level proinflammatori cytokin accompani rapid weight loss increas morbid mortal result suggest time level immunostimulatori dvgs generat infect contribut hn pathogenesi import mammalian infect high pathogen avian influenza virus hpaiv caus sever diseas associ excess proinflammatori cytokin product aberr replic product defect viral genom dvgs stimul antivir respons cytokin induct associ emerg vivo show stock recombin virus contain hpaiv intern gene differ amount dvgs vast divers outcom mous model high dvg stock result extrem mild diseas due suppress viral replic convers stock contain low dvgs rapid accumul dvgs cours infect led sever diseas therefor time dvg amplif proinflammatori cytokin product impact diseas outcom find demonstr dvg generat reduc viral virul studi also emphas crucial requir examin qualiti virus prepar regard dvg content ensur reproduc research | D009980;D053124 | T005 |
36,226,984 | zika virus infect downregul connexin disrupt cardiomyocyt gap junction induc heart diseas mice zika virus zikv transmit most via mosquito bite vaccin avail may reemerg other previous demonstr neonat infect zikv result heart failur fatal anim model implic zikv involv viral heart diseas unknown whether zikv caus heart failur adult herein studi effect zikv infect heart function adult mice first found zikv product infect rat mous human origin heart cell line caus ubiquitin mediat degrad distort effect connexin cx protein import communic cardiomyocyt second zikv infect caus death mice decreas bodi weight worsen health score shrug fur paralysi viral replic detect multipl organ search viral effect heart mice found zikv infect result increas cardiac muscl enzym implic viral acut myocardi injuri zikv caus heart injuri also demonstr electrocardiogram ecg show widen fragment qrs wave prolong pr interv slower heart rate intercal disc icd two cardiomyocyt destroy shown electron microscopi cx distribut icd less organ zikv infect mice compar phosphat buffer salin pbs treat mice consist zikv product infect heart mice decreas cx protein therefor demonstr zikv infect caus heart failur might lead fatal sequela zikv infect mice import zika virus zikv teratogen caus devast sequela newborn suffer congenit zikv infect bring mild symptom health compet older children adult mous model play import role mechanist pathogen studi zikv studi employ week old mice zikv infect rt qpcr assay discov zikv replic multipl organ includ heart result zikv infect mice experienc weight loss health score worsen paralysi death reveal zikv infect caus abnorm electrocardiogram present increas cardiac muscl enzym downregul cx destroy gap junction intercal disc cardiomyocyt implic zikv may caus acut myocardi injuri mice therefor data impli zikv infect may jeopard immunocompromis popul sever clinic consequ heart defect | D000071244;D000071243;D006331;D006333 | T047;T046;T005 |
36,226,983 | gbprin bind motif insert flexibl region nsp support rna replic chikungunya virus chikungunya virus chikv mosquito transmit alphavirus infect cell posit sens rna genom translat polyprotein subsequ process four nonstructur protein nsp virus encod subunit rna replicas howev rna replic interact nsps host protein also need interact most mediat intrins disord c termin hypervari domain hvd nsp duplic fgdf motif hvd requir interact mammalian rasgap sh bind protein gbps mosquito homolog rin interact crucial chikv rna replic studi inactiv gbprin bind motif hvd insert peptid contain either nativ inactiv gbprin bind motif flexibl region nsp nsp nsp insert nativ motif nsp nsp c terminus nsp activ chikv rna replic human cell gbp depend manner mosquito cell activ also result insert inact motif residu nsp howev effect signific larger insert sequenc contain nativ motif nonetheless chikv mutant harbor mutat hvd contain insert nativ motif nsp viabl mosquito cell contrast mutant genom contain nativ motif residu nsp replic bhk cell latter mutant form infecti progeni thus bind gbps nsp support chikv rna replic restor infect virus lack gbp bind motif hvd nsp import chikv reemerg alphavirus spread throughout countri causat agent chikungunya fever approv drug vaccin avail treatment prevent chikv infect chikv replic depend abil replicas protein interact host cell factor better understand host cell factor role viral infect increas understand chikv rna replic provid new strategi viral infect attenu demonstr motif requir bind host gbprin protein remain function transfer natur locat nsp differ replicas protein may enabl mutant virus complet full replic cycl knowledg first demonstr interact motif crucial host factor success transfer one replicas protein anoth subunit alphavirus replicas | D002646;D065632;D009033 | T047;T005;T204 |
36,226,976 | audiologist presbycusi associ tinnitus counsel practic within kwazulu natal provinc counsel play integr part manag presbycusi tinnitus counsel conduct implement patient centr care pcc show improv patient outcom howev poor implement healthcar south africa sa particular field audiolog condit | D011304;D014012 | T047;T046;T184;T037 |
36,226,975 | patient percept presbycusi associ tinnitus counsel practic within kwazulu natal provinc counsel manag psychosoci effect presbycusi associ tinnitus best conduct patient centr care pcc howev pauciti research implement pcc within audiolog patient percept counsel practic make focus patient benefit satisfact crucial furthermor pcc document suitabl address psychosoci effect hear loss associ tinnitus focus adult patient play integr part manag process provid improv patient outcom | D011304;D014012 | T047;T046;T184;T037 |
36,226,974 | impact covid speech languag hear profess low middl incom countri challeng opportun explor sinc advent coronavirus diseas covid speech languag hear slh profess global confront novel unexpect challeng | D000086382;D003147 | T047;T067;T048 |
36,226,973 | speech languag therapi educ reflect plan implement educ train covid pandem univers across world experienc lockdown closur learn institut around march advent coronavirus diseas covid lockdown closur present challeng tradit pedagog approach health scienc typic includ campus base clinic site focus activ involv face face interact work integr learn onset covid pandem result shift emerg remot teach ert learn | D000086382;D058873 | T047;T067 |
36,226,967 | immobil broad rang polypeptid frustul diatom thalassiosira pseudonana protein immobil biosilica superior reactiv specif innocu natur environ could use biolog materi industri process one recent develop techniqu live diatom silica immobil lidsi made possibl immobil protein includ multimer redox enzym via cellular excret system onto silica frustul marin diatom thalassiosira pseudonana howev number applic exampl far limit type protein appropri techniqu still enigmat appli lidsi six industri relev polypeptid includ protamin metallothionein phosphotriesteras cholin oxidas laccas polyamin synthas protamin metallothionein success immobil frustul protein fusion green fluoresc protein gfp n terminus indic lidsi use polypeptid rich arginin cystein contrast obtain mutant latter four enzym form without green fluoresc protein immobil phosphotriesteras cholin oxidas laccas show enzym activ even purif frustul presenc wtvol octylphenoxi poli ethyleneoxi ethanol immobil branch chain polyamin synthas chang intracellular polyamin composit silica nanomorpholog result illustr possibl lidsi industri applic import protein immobil biosilica superior reactiv specif innocu natur environ could use biolog materi industri process live diatom silica immobil lidsi recent develop techniqu vivo protein immobil diatom frustul aim explor possibl use lidsi industri applic success immobil six polypeptid protamin oncorhynchus keta stabl antibacteri agent ii metallothionein saccharomyc cerevisia metal adsorpt molecul use bioremedi iii phosphotriesteras sulfolobus solfataricus scaveng toxic organ phosphat iv cholin oxidas arthrobact globiformi enhanc photosynthet activ yield plant v laccas bacillus subtili phenol oxidas util delignif lignocellulos materi vi branch chain polyamin synthas thermococcus kodakarensi produc branch chain polyamin import dna rna stabil high temperatur studi provid new insight field appli biolog materi | D017377;D044345 | T126;T116;T204 |
36,226,965 | integr assess reduc listeria monocytogen suscept benzalkonium chlorid produc process environ decad quaternari ammonium compound qac base sanit broad use food process environ control foodborn pathogen listeria monocytogen still lack consensus likelihood implic reduc listeria suscept benzalkonium chlorid bc may emerg due subleth exposur sanit food process environ focus fresh produc process attempt fill multipl data evid gap surround debat determin strong correl toler phenotyp known genet determin bc toler extens set fresh produc isol assess bc select l monocytogen larg scale sourc structur genom survey public avail l monocytogen genom divers sourc unit state consider process environ constraint monitor tempor onset durat adapt bc toler toler sensit isol final examin residu bc concentr throughout fresh produc process facil differ time point daili oper genom evid support elev bc select recommend sanit rotat general context food process environ also suggest mark variat occurr potenti impact select among differ commod sector process fresh fruit veget conclud proper sanit clean facil less affect bc select unlik provid condit conduc emerg adapt bc toler l monocytogen import studi demonstr integr approach improv food safeti assess control strategi food process environ collect leverag genom survey laboratori assay process facil sampl exampl assess reduc listeria suscept wide use sanit approach yield multifacet evid incorpor popul genet signal experiment find real world constraint help address last debat polici practic import | D008089;D008087 | T007 |
36,226,964 | effect backbon flexibl coval templat direct synthesi linear oligom coval templat direct synthesi use replic synthet oligom success depend critic conform properti backbon investig choic monom build block affect flexibl backbon turn effici replic process seri differ triazol oligom two compet reaction pathway identifi monom attach templat result format either macrocycl linear product flexibl backbon macrocycl linear oligom form similar rate rigid backbon gave exclus linear product experiment result consist ring strain calcul use molecular mechan product low ring strain kj mol form rapid product high ring strain gt kj mol observ templat direct replic linear oligom requir monom rigid enough prevent format undesir macrocycl rigid linear templat pathway lead duplex inhibit molecular mechan calcul ring strain provid straightforward tool assess flexibl potenti backbon viabil differ monom design embark synthesi | D008968 | T082 |
36,226,960 | water stress driven chang bacteri cell surfac properti increas drought intens frequenc expos soil bacteria prolong water stress numer studi report behavior physiolog mechan bacteri adapt water stress chang bacteri cell surfac properti adapt well research studi adapt chang cell surfac hydrophob csh exposur osmot nacl matric stress polyethylen glycol peg six typic soil bacteria bacillus subtili arthrobact chlorophenolicus pseudomona fluorescen novosphingobium aromaticivoran rhodococcus erythropoli mycobacterium pallen cover wide rang cell surfac properti addit physicochem paramet surfac chemic composit surfac charg cell size stiff b subtili p fluorescen analyz understand possibl contribut csh develop chang csh caus osmot matric stress depend strain stress type csh b subtili p fluorescen increas stress intens r erythropoli pallen exhibit general high constant contact angl respons chlorophenolicus n aromaticivoran depend growth condit stress type osmot driven chang csh b subtili p fluorescen accompani increas surfac nc ratio suggest increas protein concentr within cell wall cell envelop protein thus presum control bacteri csh two way increas relat densiti surfac protein due efflux cytoplasm water subsequ cell shrinkag ii destabil cell wall protein result conform chang render surfac hydrophob import chang precipit frequenc intens tempor distribut project result increas frequenc intens drought heavi rainfal event prolong drought promot develop soil water repel swr impact infiltr distribut water soil profil expos soil microorgan water stress exposur water stress recent report result increas cell surfac hydrophob howev mechan develop poor understood studi investig chang physicochem properti bacteri cell surfac water stress possibl mechan increas surfac hydrophob result improv understand microbi respons water stress term surfac properti variat stress respons depend cell wall composit contribut develop swr | D003681;D012987 | T047;T167 |
36,226,956 | navig postgradu research covid pandem scope review worldwid coronavirus diseas covid pandem compel higher educ institut postgradu student master phd rethink research design alert level restrict affect data collect | D000086382;D058873 | T047;T067 |
36,226,955 | viral suppress among adolesc hiv treatment sedibeng district gauteng provinc progress made increas access antiretrovir therapi art adolesc live hiv alhiv improv surviv alhiv still wors treatment adher viral suppress compar adult children | D019380;D015658 | T121;T047 |
36,226,953 | palpabl breast lump age base approach evalu diagnosi palpabl breast lump common present breast diseas general practition fortun investig lump lead benign diagnosi essenti clear systemat approach investig palpabl breast lump avoid investig result increas healthcar cost anxieti articl discuss approach evalu diagnos palpabl breast lump primari care set | D001941;D008327 | T047;T060 |
36,226,952 | pandem guid sar cov pcr test clinician know amidst ever evolv pandem demand time accur diagnosi coronavirus diseas covid continu increas critic manag contain spread diseas requir expedi test infect individu present gold standard diagnosi sever acut respiratori syndrom coronavirus sar cov infect remain polymeras chain reaction pcr test potenti vulner test methodolog rang preanalyt variabl laboratori relat analyt factor ultim interpret result | D000086382;D058873 | T047;T067 |
36,226,951 | patient percept servic qualiti healthcar profit organis servic organis awar element perceiv excel qualiti incorpor part servic offer howev profit npo healthcar organis consist divers group stakehold differ perspect interest servic qualiti therefor requir multidimension definit comprehend need expect | D006268;D017060 | T093;T073;T080 |
36,226,950 | current norm practic use seizur diari manag epilepsi scope review epilepsi chronic debilit condit affect peopl age mani nation healthcar practition look effect way track patient seizur seizur diari one method use scope review sought identifi current norm practic use seizur diari manag epilepsi | D004827;D012640 | T047;T046;T184;T033 |
36,226,949 | covid diabet ketoacidosi case seri urban district hospit south africa coronavirus diseas covid associ increas preval mortal diabet ketoacidosi dka global limit access specialis care patient dka south africa manag district hospit level studi describ profil patient admit district hospit south africa dka covid examin associ risk factor encount | D000086382;D003924;D016883;D008687 | T121;T047;T109;T067 |
36,226,948 | utilis villag health worker servic tuberculosi screen lesotho villag health worker vhws play essenti role extend capac primari healthcar particular develop countri lesotho vhws part primari healthcar connect communiti clinic respect villag contribut prevent spread tuberculosi tb within catchment area encourag communiti partak tb screen studi aim identifi factor associ utilis vhws servic undertak tb screen lesotho | D003150;D014376 | T047;T097;T102 |
36,226,947 | oxygen drug scarc commod use ration medic grade oxygen classifi drug need prescrib qualifi healthcar profession oxygen therapi prescrib peopl maintain normal blood oxygen satur breath atmospher air coronavirus diseas covid pandem highlight import ration use scarc commod studi investig oxygen therapi practic adult ward patient | D000086382 | T047;T067 |
36,226,946 | knowledg final year undergradu nurs student hiv aid eswatini human immunodefici virus hiv acquir immun defici syndrom aid overwhelm health issu global caus mani devast drain health issu escal critic need well train sustain healthcar workforc order meet need peopl live hiv aid plwha health scienc student futur healthcar provid implement proper prevent measur well health educ promot session promot inform knowledg among public regard hiv aid eswatini | D000163;D004508;D015658;D013338 | T047;T097;T065 |
36,226,941 | leaf mycobiom mycotoxin profil warm season grass structur plant speci geographi appar black stroma fungal structur grass harbor divers fungi includ produc mycotoxin secondari metabolit recent florida cattl farmer report cattl ill cattl graze warm season grass pastur attribut common caus nutrit imbal nitrat toxic understand correl grass mycobiom mycotoxin product investig mycobiom associ five promin perenni forag weed grass paspalum notatum flgge cynodon dactylon l per paspalum nicora parodi sporobolus indicus l r br andropogon virginicus l collect six florida pastur activ graze livestock black fungal stromata myriogenospora balansia observ p notatum indicus leav investig high throughput amplicon sequenc appli delin leaf mycobiom mycotoxin p notatum leav inspect use liquid chromatographi mass spectrometri lc msms grass speci cultivar geograph local interact affect fungal communiti assembl asymptomat leav among grass speci greatest fungal rich detect weed indicus black fungal structur p notatum leav domin genus myriogenospora indicus codomin genus balansia hypermycoparasit fungus genus clonostachi compar mycotoxin detect p notatum leav without atramentosa emodin anthraquinon compound signific differ p understand leaf mycobiom mycotoxin may produc warm season grass import implic associ lead secondari metabolit product subsequ impact anim health import leaf mycobiom forag grass major impact mycotoxin content forag subsequ affect livestock health despit import cattl industri warm climat region florida studi primarili limit temper forag system studi provid holist view leaf fungi consid epibiot endophyt hypermycoparasit associ five perenni warm season forag weed grass highlight plant ident geograph locat interact affect leaf fungal communiti composit yeast appear overlook fungal group healthi forag mycobiom furthermor detect high emodin quantiti leav wide plant forag speci p notatum whenev epibiot fungi occur studi demonstr import identifi fungal communiti ecolog role secondari metabolit perenni warm season grass potenti interf livestock health | D000072761;D009183;D004642 | T131;T121;T109;T123;T004 |
36,226,938 | climat chang disast manag primari health care zimbabw health crise relat climat chang african countri predict get wors preval respons catastroph event cyclon flood landslid must rapid well coordin slower advers event drought heat stress food insecur must similar anticip plan resourc lesson learnt health system follow crisi creat cyclon idai zimbabw march requir massiv humanitarian respons mitig impact torrenti rainfal live livelihood sever research organis document emerg respons detail report govern respons hamper lack prepared poor plan inadequ resourc mobilis weak coordin rural communiti access earli warn cyclon alert dissemin televis print social media appreci serious event late primari health care phc team familiar trust communiti serv critic role rais public awar document evolv impact climat chang use establish health indic local narrat phc leader provid knowledg skill mediat govern bodi intern agenc stakehold communiti predict impact climat chang health outcom highlight vulner disadvantag impoverish group also abl work communiti leader use indigen knowledg weather pattern build local engag protect planscontribut articl describ role health profession civil societi play educ public danger face near futur result climat chang action taken becom resili mitig impact | D004189;D004190 | T064;T067;T052 |
36,226,937 | climat chang primari health care chakama kilifi counti kenya chakama area small villag kilifi counti kenya climat chang led frequent longer period drought semi arid region well locust invas led lack water mani river dri poor water qualiti result pollut remain river water lack water locust invas led failur crop loss livestock mani pastoralist farmer lost livelihood wild anim local natur reserv also come conflict communiti water scarciti mani famili migrat search water incom health effect seen rise number peopl suffer malnutrit gastroenter well term mental health problem primari health care servic alway avail qualiti servic poor facil healthcar worker also struggl resili face environment challeng local nongovern organis attempt assist health social servic communiti engag multisector action | D057231;D058751 | T008;T070 |
36,226,936 | knowledg attitud percept toward lower limb amput amongst person live diabet rural south africa qualit studi south africa high preval diabet mellitus dm lead risk factor lower limb amput lla lower limb amput associ signific morbid mortal lower limb amput incid mitig prompt identif treatment individu risk engag self manag practic also lla inevit outcom prognosi improv time surgeri | D003920;D012424 | T098;T047;T102 |
36,226,935 | compar studi postnat depress associ factor gauteng free state provinc south africa factor contribut probabl postnat depress pnd type clinic depress affect woman childbirth social deriv therefor variat among group women necessit studi differ communiti | D019052 | T048 |
36,226,934 | choix thrapeutiqu des hypertendus et diabtiqu en milieu rural une tude mixt dan deux zone de sant de lest de la rpubliqu dmocratiqu du congo therapeut choic hypertens diabet rural area mix studi two health zone east democrat republ congo | D006973 | T047 |
36,226,933 | role tradit belief knowledg percept mental health ill amongst rural dwell women western nigeria global public health import mental health gain signific attent recent year africa mani tradit belief system impact percept attitud manag mental ill women usual primari caregiv mental ill person lower mental health literaci | D008603;D012424 | T098;T041;T102 |
36,226,932 | manag acut opioid withdraw tramadol covid lockdown peri urban set coronavirus diseas covid highlight scope heroin depend need evid base treatment amongst marginalis peopl south africa acut opioid withdraw manag without mainten therapi carri risk increas morbid mortal due high cost methadon tshwane communiti orient substanc use programm cosup use tramadol opioid withdraw manag initi covid respons | D000086382;D013375;D014147 | T047;T121;T109;T048;T184;T067 |
36,226,931 | percept women toward screen intim partner violenc intim partner violenc ipv diagnos public health problem affect women attend negat bio psycho social ramif unfortun univers agre recommend routin hospit ipv screen current | D017579;D000066511 | T054;T053;T048 |
36,226,930 | develop zimbabwean child growth curv comparison world health organ child growth standard limit research describ growth trajectori african children develop world health organ growth standard consid sampl children live environ optimum human growth | D001827 | T032 |
36,226,929 | salient belief modifi risk behaviour among patient live diabet hypertens qualit format studi although evid key role play focus local knowledg design appropri intervent regard modifi risk behaviour among patient live diabet hypertens mangochi malawi littl known local salient belief | D003920;D006973 | T047 |
36,226,928 | relationship bodi composit physic fit primari school learner predomin rural provinc south africa lack literatur regard relationship exist bodi composit physic fit amongst primari school learner south africa sake public health purpos import investig bodi composit relat physic fit amongst primari school learner eastern cape provinc south africa | D001823;D010809 | T078;T032 |
36,226,926 | molecular basi simultan enhanc aroma generat capac bioactiv maillard reaction precursor mechanochemistri ball mill ambient temperatur acceler format accumul earli stage maillard reaction intermedi consid import precursor aroma antioxid studi use chemic biolog assay explor potenti sequenti mill heat enhanc antioxid aroma generat capac maillard model system mill hz min follow dri heat c min glycin lysin glucos signific increas intens aroma activ compound analyz headspac gas chromatographymass spectrometri hs gcms also free radic scaveng capac assess azino bis ethylbenzothiazonelin sulfon acid abt oxygen radic absorb capac orac assay attribut increas format redox activ endiol moieti precursor n n dialkyl pyrazinium radic cation lysin system assess electrospray ionize quadrupol time flighttandem mass spectrometri esi qqtofmsm analysi test sampl also inhibit generat cellular oxid stress raw murin macrophag cell indic size reduct induc mill promot paracellular absorpt | D015416;D000975 | T121;T123;T070;T044;T039 |
36,226,922 | fucosyl chondroitin sulfat parkinson diseas inhibit inflamm induc gut dysbiosi grow evid import gut brain axi parkinson diseas pd attract research interest possibl applic microbiota base treatment approach use methyl phenyl tetrahydropyridin mptp induc mous model look prospect treat pd fucosyl chondroitin sulfat obtain sea cucumb isostichopus badionotus fcs ib show give fcs ib polysaccharid oral great reduc motor deficit dopamin deplet alpha synuclein increas caus mptp substantia nigra sn appear anti pd action fcs ib polysaccharid could attain squelch inflamm glial cell hyperactiv sn overproduct proinflammatori substanc serum could suppress fcs ib polysaccharid inject bacteri dna fresh colon fece submit rrna untarget metabol analys confirm particip microbiota gut brain axi aforement interpret find show mptp treatment induc decreas norankfmuribaculacea increas staphylococcus revers administr fcs ib polysaccharid nf b signal pathway shown involv fcs ib polysaccharid induc anti inflamm conclus research demonstr first time fcs ib polysaccharid combat pd reduc inflamm caus gut microbi dysbiosi | D010300;D012616 | T047;T204 |
36,226,914 | ros respons nanocomplex apd l cabazitaxel improv intratumor deliveri potenti radiat mediat antitumor immun despit promis benefit immun checkpoint inhibitor ici clinic cancer treatment therapeut efficaci larg restrict low antitumor immun limit intratumor deliveri solid tumor herein design reactiv oxygen speci ros respons albumin nanocomplex antiprogram cell death receptor ligand apd l cabazitaxel ran pc exhibit promin tumor accumul intratumor permeat tumor compar negat control ran pc radiat treatment ran pcx produc fold enhanc cd cd cell interferon ifn express subtyp respect notabl reduc versatil immunosuppress cell moreov ran pcx treatment result notabl retard tumor growth inhibit breast tumor model suppress ct colon tumor model therefor ros respons albumin nanocomplex offer encourag platform ici promin intratumor deliveri capac cancer immunotherapi | D060890;D018414 | T025;T116;T129 |
36,226,913 | earli life stress experi escal aggress behavior adulthood via chang transthyretin express function escal inappropri level aggress behavior refer patholog psychiatri lead violent outcom detriment impact health societi earli life stress experi might increas risk develop patholog aggress behavior adulthood though molecular mechan remain elus provid prefront cortex hypothalamus specif transcriptom profil peripubert stress pps expos balbc adult male mice exhibit escal aggress adult femal mice resili aberr behavior respons identifi transthyretin ttr well known thyroid hormon transport key regul pps induc escal aggress behavior male brain region specif long term chang ttr gene express thyroid hormon th avail evid pps induc escal aggress male mice circul th unalt ttr promot methyl mark also alter hypermethyl hypothalamus hypomethyl prefront cortex corrobor express pattern ttr knockdown hypothalamus result escal aggress behavior male without pps also reduc th level express th respons gene nrgn trh hr escal aggress behavior along reduc ttr gene express th level hypothalamus also evid next generat f male progeni find reveal stress experi puberti might trigger last escal aggress modul ttr express brain ttr serv potenti target revers escal aggress relat psychopatholog | D011228;D012741 | T040;T123;T116 |
36,226,912 | compoundray open sourc tool high speed high fidel render compound eye reveal function compound eye interest biologist engin alik wish understand visual complex behaviour eg detect track navig aris natur abstract concept develop novel artifici sensori system key investig method replic sensori apparatus use artifici system allow investig visual inform drive anim behaviour expos environment cue date compound eye model cem larg explor featur field view angular resolut role shape overal structur larg overlook due model complex modern real time ray trace technolog enabl construct new generat comput fast high fidel cem work introduc new open sourc cem softwar compoundray capabl accur render visual perspect bee individu ommatidia arrang realist eye surfac frame per second show speed accuraci facilit softwar use investig press research question eg low resolut compound eye localis small object use modern method eg machin learn base inform explor | D001516;D054910 | T023;T204 |
36,226,909 | asymmetr interfacet adatom migrat mode anisotrop nanocryst growth crystal known grow nonclass via four classic mode layer layer disloc driven dendrit normal mode general involv minim interfacet surfac diffus field nanosci consid framework interpret nanocryst grow yet growth mani anisotrop nanocryst remain enigmat suggest framework may incomplet studi solut phase growth pentatwin au nanorod without br ag surfact lower supersatur condit favor anisotrop growth appear varianc known mode tempor electron microscopi reveal kinet limit adatom funnel adatom diffus asymmetr along vicin facet situat inbetween side facet end facet nanorod vicin facet perpetu throughout synthesi especi lower supersatur facilit vicin adatom diffus deriv growth model classic theori view find show experiment growth kinet consist nanorod grow via two mode simultan radial growth occur via layer layer mode side facet wherea asymmetr interfacet diffus adatom end facet mediat longitudin growth thus shape anisotropi driven modul relat rate monom deposit differ facet convent thought rather modul relat rate monom integr via interfacet diffus work show control supersatur thermodynam paramet uncov distinct kinet phenomena nanocryst asymmetr interfacet surfac diffus fundament growth mode monom deposit integr occur differ facet | D053768;D043942 | T073 |
36,226,906 | qualiti publish health econom evalu screen program china systemat review quantit apprais studi seek assess qualiti hee report screen program last year china identifi potenti predictor report qualiti | D008403;D057189 | T058;T170;T060 |
36,226,883 | burden other mani peopl afraid age fall ill becom burden other fear say would will hasten death engag self sacrific suicid assist suicid euthanasia avoid still bioethicist critic medic aid die reject idea fear burden good reason self sacrific argu depend near univers emphas caregiv valuabl pursuit rais concern impact aid die polici vulner group defin burden articul burden moral signific crucial distinguish burdensom call mere depend defend intuit self sacrific justifi desir avoid burden concern well one caregiv choic impli | D005065;D017236 | T054;T058 |
36,226,882 | author advanc euthanasia direct peopl sever dementia reflect dutch case dutch physician compli advanc euthanasia direct patient sever dementia ensu lawsuit physician charg princip termin life request euthanasia altern murder district court acquit charg decis later upheld dutch suprem court euthanasia still crimin offens netherland new euthanasia act came effect allow physician perform euthanasia fulfil six due care criteria two import must satisfi patient request voluntari well consid patient suffer unbear prospect improv neither two criteria controversi particular case controversi disput criteria fulfil euthanasia case howev controversi belong categori contenti independ reason one disput categori euthanasia perform incompet patient advanc direct sinc determin whether criteria fulfil particular case depend particular circumst describ case detail focus three general philosoph reason doubt valid advanc euthanasia direct incompet patient someon els problem problem respons shift problem normat author problem discuss primari aim show connect taken togeth believ two line argument make strong moral case support dutch suprem court decis | D003704;D005065;D010820 | T097;T058;T048 |
36,226,881 | zoonos anim cull need one health polici one health oh biomed social movement call reorient public health approach toward holist nonanthropocentr approach exclud interest anim ecosystem oh thus urg reexamin scientif moral perspect practic cull pet farm wild anim face zoonosi pandem covid monkeypox highlight need rigor analysi justif tradit provid back cull practic analys ground reason oh polici legisl consid right human anim environ bill advanc emerg prepared one health act introduc us congress step right direct | D000086382;D000074823 | T078;T047;T067 |
36,226,880 | error convert principl protocol bioethic us covid vaccin alloc went wrong much alloc scarc suppli covid vaccin world press bioethic challeng similar challeng may recur novel therapi futur vaccin unit state center diseas control prevent advisori committe immun practic acip identifi three fundament ethic principl guid process maxim benefit promot justic mitig health inequ argu critic compon recommend protocol intern inconsist principl specif acip violat principl recommend over broad health care worker prioriti phase use least seventi five year age criterion identifi individu high risk death covid phase b fail recommend place base vaccin distribut implicit endors first come first serv alloc rigor empir work develop complet ethic framework recogn trade off principl may prevent mistak save live | D001675;D000086382;D014612 | T047;T116;T121;T091;T129;T067 |
36,226,879 | assess technolog bioethicist must take blinker assess safeti biomed technolog essenti aspect sound ethic assess howev suffici technolog signific design accomplish bioethicist pay attent mani way technolog transform world | D001675;D026822 | T091;T097 |
36,226,878 | us lawsuit claim feder law requir emerg abort wake us suprem court overrul roe vs wade state pass strict antiabort law biden administr argu violat feder emerg medic treatment activ labor act emtala state law permit emerg life save abort feder law say must avail patient biden administr file suit idaho portion state law invalid texa file suit biden administr argu interpret emtala requir abort avail patient emerg circumst amount unconstitut overreach feder govern suit other relat may redefin health relat feder unit state | D000028 | T093;T046;T061;T081;T033 |
36,226,877 | choos die two articl septemb octob issu hast center report discuss health relat reason peopl might activ bring live end one brent kious consid situat person ill becom burden love one person situat might prefer die kious argu oblig hasten one death choic could sometim reason second articl henri wijsbek thoma nys discuss case netherland woman sever dementia euthan point advanc euthanasia direct align said ask death wijsbek nys defend author advanc direct rang object third articl henri silverman patrick odonkor physician univers maryland medic center first pig human heart transplant perform earli develop recommend clinic trial porcin heart transplant essay issu critic alloc recommend develop covid vaccin us center diseas control prevent advisori committe immun practic | D000086382;D003704;D010820 | T047;T097;T067;T048 |
36,226,876 | xenotransplant clinic trial need communiti engag sever ethic concern face first human clinic trial involv xenotransplant particip trial limit trial particip exhaust treatment option avoid therapeut misconcept balanc desir long term monitor trial particip well establish principl research particip right withdraw research final balanc concern equit access trial deep mistrust scientif communiti particular xenotranspl clinic trial attempt address well known inequ clinic trial particip race ethnic commentari argu clinic investig regul oblig engag underrepres communiti develop answer question | D014183 | T061 |
36,226,875 | reevalu ethic issu porcin human heart xenotransplant major limit factor heart allotransplant remain avail organ deceas donor porcin heart xenotransplant could serv altern sourc organ patient termin heart failur first human porcin xenotransplant occur januari univers maryland medic center provid opportun examin sever ethic issu guid select criteria futur xenotransplant clinic trial articl author clinician ummc discuss appropri balanc risk benefit signific clinic equipois author also review alleg role psychosoci evalu identifi patient elev risk posttranspl noncompli consid evalu implement might enhanc inequ among divers popul author argu base principl reciproc psychosoci criteria use exclud patient instead identifi patient need addit support final author discuss requir proper assess inform voluntari consent patient consid xenotransplant | D014019 | T098 |
36,226,838 | wetland cohes associ increas probabl infect amphibian chytrid fungus batrachochytrium dendrobatidi amphibian chytrid fungus batrachochytrium dendrobatidi bd pose substanti threat amphibian popul understand landscap condit facilit bd transmiss persist crucial predict bd trend amphibian popul investig interact land use wetland connect bd occurr infect intens northeastern massachusett sampl pseudacri crucif lithob sylvaticus l clamitan l pipien site found overal bd preval site preval differ among speci bd occurr increas wetland patch cohes potenti due microclim shift decreas forest chang host movement bd infect intens mediat landscap context overal result highlight import landscap structur bd dynam suggest certain landscap may facilit transmiss harbor bd other mitig impact bd amphibian popul conserv effort account interact bd landscap variabl | D000663;D000084662;D009181;D053833 | T047;T083;T011;T070;T004 |
36,226,829 | differ immun respons elicit two immun schedul inactiv sar cov vaccin random phase clinic trial develop vaccin control coronavirus diseas covid pandem progress worldwid prioriti coronavac inactiv sever acut respiratori syndrom coronavirus sar cov vaccin approv emerg use robust efficaci immunogen data report trial china brazil indonesia turkey chile | D000086382;D000086663;D007115 | T061;T047;T200;T067 |
36,226,828 | antibacteri tss effector vrr nuc domain structur specif nucleas type vi secret system tss secret antibacteri effector target competitor salmonella spp encod five phylogenet distinct tsss character function spi tss salmonella bongori show antibacteri activ identifi group antibacteri tss effector tsev contain n termin paar like domain c termin vrr nuc domain encod next cognat immun protein duf domain tsiv tsev tsev toxic express escherichia coli bacteri competit assay confirm tsev tsev secret spi tss phylogenet analysi reveal tsev evolutionarili relat enzym involv dna repair tsev recogn specif dna structur preferenti cleav splay arm generat dna doubl strand break induc sos respons target cell crystal structur tsev tsiv complex reveal immun protein like block effector interact dna substrat result expand knowledg function salmonella pathogen island evolut toxin use biolog conflict endogen mechan regul activ toxin | D001426;D000069376 | T123;T116 |
36,226,826 | postsynapt burst reactiv hippocamp neuron enabl associ plastic tempor discontigu input fundament unresolv problem neurosci brain associ memori event separ time propos reactiv induc synapt plastic solv problem previous report reinforc signal dopamin convert hippocamp spike time depend depress potenti continu synapt activ brzosko et al report postsynapt burst presenc dopamin produc input specif ltp mous hippocamp synaps min prime coincid pre post synapt activ post pre pair ms prime activ induc synapt depress set nmda receptor depend silent elig trace camp pka cascad rapid convert protein synthesi depend synapt potenti mediat signal pathway distinct convent ltp synapt learn rule incorpor comput model found add specif reinforc learn control memori alloc enabl instruct supervis reinforc learn predict mechan would make reactiv neuron activ strong carri spatial inform non reactiv cell confirm freeli move mice perform reward base navig task | D004298;D009474 | T121;T025;T109;T123 |
36,226,824 | pavlovian condit gentoo penguin pygosc papua underwat sound penguin known react underwat nois unknown make use sound cue dive test whether captiv gentoo penguin pygosc papua pair underwat sound food pavlovian condit two second underwat sound khz sweep receiv level db pa rms play back one two unidentifi penguin dead fish flush water close underwat sound sourc week condit one individu penguin approach sound sourc sound emiss trial intermix control trial sound preced fish penguin show reaction pre flush period addit experi three identifi penguin react sound trial reaction five intermix control trial experi demonstr gentoo penguin condit underwat sound associ underwat sound food possibl gentoo well speci penguin use sound cue forag may explain penguin observ react negat anthropogen nois | D046429 | T012 |
36,226,823 | prenat perinat phthalat exposur associ sex depend chang hippocamp mir b p mir p express chang testicular morpholog rat offspr microrna larg group non code nucleic acid usual nt long bind regulatori section messeng rna mrna inhibit gene express howev genom activ also regul hormon endocrin disruptor phthalat group imit block hormon effect previous studi show long last decreas plasma testosteron level rat offspr expos mixtur three phthalat utero postnat effect also observ behaviour level shed light find new studi compar testicular tissu morpholog control phthalatetr male investig possibl persist chang sex differ express two hippocamp microrna mir b p mir p particip transcript steroidogen gene histolog observ chang testicular tissu morpholog phthalat expos male compar control support testosteron drop observ previous studi microrna level observ signific chang phthalat treat femal male howev unabl relat effect previous observ behaviour chang | D052244;D035683;D010795 | T131;T109;T123;T114;T039 |
36,226,822 | effect low dose chlorpyrifo blood bone marrow cell wistar rat aim studi investig genotox potenti low dose chlorpyrifo cpf blood bone marrow cell adult male wistar rat cpf administ oral gavag daili dose mgkg bodi weight bw consecut day posit control pc administ mgkg bwday ethyl methan sulphon em final three day experi toxic outcom exposur determin vivo micronucleus mn assay alkalin comet assay day exposur mgkg cpf dose three time higher current valu acut refer dose arfd reduc bodi weight gain rat vivo mn assay show signific differ number reticulocyt per erythrocyt pc negat control nc control group group expos mgkg bwday cpf number micronucl polychromat erythrocyt per erythrocyt signific higher pc nc group group expos mgkg bwday cpf cpf treatment signific increas primari dna damag bone marrow cell compar nc group howev damag bone marrow cell cpf expos rat much higher one record leukocyt establish previous research assay prove success assess cpfinduc genom instabl wistar rat howev exact mechan damag investig confirm sensit method | D004390 | T109;T131 |
36,226,821 | redox biomet status wistar rat subacut exposur fluorid selenium counter effect studi aim investig effect mgl sodium fluorid naf redox status paramet essenti metal copper cu iron fe zinc zn blood liver kidney brain spleen wistar rat determin protect potenti selenium se fluorid f toxic male wistar rat random distribut group five n receiv tap water control water naf mgl naf mgl se mgl se mgl solut ad libitum day fluorid caus imbal redox biomet cu fe zn status lead high superoxid anion malondialdehyd mda level blood brain drop superoxid dismutas sod activ liver increas brain kidney se given naf improv mda sod blood brain kidney alon decreas sh group level liver kidney biomet reduc increas f toxic research need se consid promis strategi mitig f toxic | D012643;D014131 | T121;T123;T196 |
36,226,819 | whey protein protect liver mitochondri function oxid stress rat expos acrolein acrolein ac one toxic environment pollut often associ incomplet combust petrol wood plastic oil fri tobacco smoke caus oxid damag dna mitochondria consid littl known protect effect whey protein wp ac induc liver toxic aim studi learn respect liver mitochondri oxid stress respiratori enzym kreb cycl enzym adenosin triphosph atp treat spragu dawley rat daili dose ac alon mgkg bw nacl solut wp alon mgkg bw nacl solut combin oral gavag six day week day expect ac group show drop glutathion level antioxid transport chain tricarboxyl acid cycl enzym activ signific rise mitochondri lipid peroxid protein carbonyl level co treatment wp mitig oxid stress improv enzym activ judg measur paramet wp reduc ac toxic improv bioenerget mechan elimin oxid stress | D000171;D004785 | T109;T131;T130 |
36,226,818 | occup burnout among teacher season aim cross section studi compar occup burnout two group teacher district bijeljina bosnia herzegovina measur serbian version maslach burnout inventori survey worker human servic mbi hss begin group end school year group see season differ questionnair also includ standard sociodemograph data job descript primari andor secondari school posit length servic overtim work preval emot exhaust depersonalis low group howev emot exhaust depersonalis score signific shift higher valu begin end school year also found statist signific associ emot exhaust overtim depersonalis work secondari school p find invit research occup burnout season schoolteach prefer follow cohort would control sociodemograph work relat variabl | D002055 | T048 |
36,226,817 | medic devic sourc phthalat exposur review current knowledg altern solut phthalat group phthalic acid ester use plasticis larg number product improv flexibl soft extens wide use medic devic howev rais lot concern enter organ toxic effect human liver thyroid kidney lung reproduct endocrin nervous respiratori system associ asthma obes autism diabet aim review summaris current knowledg phthalat migrat medic devic differ medic procedur possibl impact patient health also look altern plasticis suppos lower migrat rate safer profil enough known mani phthalat make part medic devic health impact altern plasticis migrat rate | D010795 | T109 |
36,226,815 | vocal categor behavior explain featur base auditori categor model vocal anim produc multipl categori call high within subject variabl listen must general accomplish call categor behavior strategi neural mechan support abil general larg unexplor previous propos theoret model accomplish call categor detect featur intermedi complex best contrast call categori categori demonstr neural respons primari auditori cortex consist model ask whether featur base model could predict call categor behavior train model guinea pig gps call categor task use natur call test categor model gps use tempor spectral alter call model gps surpris resili tempor manipul sensit moder frequenc shift critic model predict varianc gp behavior adopt differ model train strategi examin featur contribut solv specif task could gain insight possibl strategi use anim categor call result valid model use detect intermedi complex contrast featur accomplish call categor | D001303 | T023;T029 |
36,226,814 | neuron temperatur percept induc specif defens enabl c elegan cope enhanc reactiv hydrogen peroxid high temperatur hydrogen peroxid common reactiv chemic organ face microbi battlefield rate hydrogen peroxid damag biomolecul requir life increas temperatur yet littl known organ cope temperatur depend threat show caenorhabd elegan nematod use temperatur inform perceiv sensori neuron cope temperatur depend threat hydrogen peroxid produc pathogen bacterium enterococcus faecium nematod preemptiv induc express specif hydrogen peroxid defens respons percept high temperatur pair sensori neuron neuron communic temperatur inform target tissu express defens via insulinigf hormon first exampl multicellular organ induc defens chemic sens inher enhanc reactiv chemic | D017173;D029742 | T116;T204 |
36,226,812 | drosophila hemocyt recogn lymph gland tumor mxc mutant activ innat immun pathway reactiv oxygen speci depend manner mechan cancer cell recognit elimin innat immun system remain unclear immun signal pathway activ fat bodi suppress tumor growth mxcmbn hematopoiet tumor mutant drosophila induc antimicrobi peptid amp investig regulatori mechan under activ mutant first found reactiv oxygen speci ros accumul hemocyt due induct dual oxidas one activ requir amp induct tumor growth suppress next hemocyt transplant normal larva associ mutant tumor normal lymph gland lgs matrix metalloproteinas mmp high express tumor basement membran compon tumor reduc ultim lost insid deplet mmp rather mmp result signific reduc amp express mutant larva hemocyt may recogn disassembl basement membran tumor activ ros product find highlight mechan via macrophag like hemocyt recogn tumor cell subsequ convey inform induc amp fat bodi contribut uncov role innat immun system cancer | D004330;D029721 | T123;T116;T204 |
36,226,799 | comput studi reveal mechanist origin distinct perform p hoh compound palladium catalyz hydrophosphoryl termin alkyn switchabl mechan potenti side reaction pd catalyz hydrophosphoryl alkyn p h compound provid atom econom oxid free access alkenylphosphoryl compound nevertheless applic p h substrat limit without hydroxyl group except h p oh also puzzl ph p oh could co catalyz reaction improv markovnikov select herein comput studi conduct elucid mechanist origin phenomena describ found switchabl mechan influenc acid substrat co catalyst oper hydrophosphoryl addit potenti side reaction caus proton pd ii alkenyl intermedi p oh speci reveal regener activ pd catalyst result pd ii complex remark slower hydrophosphonyl downstream reaction possibl would lead phosphorus pyron analysi indic side reaction could suppress util bulki substrat ligand decreas concentr p oh speci present switchabl mechan side reaction shed light co transform p h p oh compound pd catalyz hydrophosphoryl alkyn clarifi origin distinct perform p hoh compound provid theoret clue expand applic substrat scope hydrophosphoryl synthes cyclic alkenylphosphoryl compound | D010165;D000480 | T109;T196 |
36,226,790 | lycopen amelior skin age regul insulin resist pathway activ sirt microvascular loss one import characterist skin age sever microvascular activ play key role preserv skin health vitro lycopen ly reduc content reactiv oxygen speci ros galactosidas advanc glycosyl end product age increas content atp nad nadh along mitochondri membran potenti mmp furthermor express fibrillin vegf increas age primari skin fibroblast cell prsfs lc ms non target cell metabolom demonstr mechan ly lycopen protect age skin cell kegg analysi predict pathway involv vivo age rat exhibit sign reduc capillari densiti blood flow skin age mitochondri disord insulin resist follow ly intervent phenomena revers meanwhil insulin pathway protein vegf sirt protein express data show lycopen might revers insulin resist promot microvascular renew protect age skin summari data demonstr ly might revers insulin resist via sirt skin age promot microvascular neovascular protect age skin | D007333;D015595 | T042;T046;T033 |
36,226,788 | discuss methadon initi protocol case report concret case discuss main publish protocol initi methadon illustr advantag disadvantag rapid gradual initi demand fix dose rescu dose daili dose vari wide depend protocol chosen demand administr could lead overdos illustr case better understand particular limit protocol could lead safer methadon initi systemat comparison differ protocol calcul daili dose standard clinic practic | D062787;D009293 | T048;T037 |
36,226,787 | share decis make opioid prescrib minim invas hysterectomi prospect random control trial determin impact share decis make postsurg opioid prescrib women underw minim invas mis hysterectomi | D000701;D010098 | T121;T109;T131 |
36,226,786 | retrospect analysi impact michigan opioid prescrib legisl discharg opioid prescrib singl institut studi sought determin chang opioid prescrib habit provid singl institut implement legisl increas opioid prescrib regul studi demonstr percent decreas overal morphin milligram equival mme prescrib year law took effect compar year prior clear law effect decreas number opioid prescrib discharg merci health grand rapid | D000701;D014147 | T121;T109;T131 |
36,226,785 | reason leav treatment among patient opioid depend month prospect follow studi studi aim ascertain reason patient opioid depend leav treatment | D002047;D009293 | T121;T109;T048 |
36,226,784 | associ request opioid medic refil hospit discharg race patient prostat cancer treat robot assist laparoscop radic prostatectomi request refil opioid one indic possibl misus aim investig racial variat request refil opioid hospit discharg robot assist laparoscop radic prostatectomi ralp | D018712;D059350;D010535;D011471;D065287 | T047;T061;T060;T121;T191;T184 |
36,226,783 | provid patient sex dispar opioid prescrib patient outcom assess sex dispar opioid prescrib practic patient outcom | D000701;D009293 | T121;T109;T131;T048 |
36,226,782 | patient engag prescript opioid use periop pain manag examin patient percept regard engag engag famili periop pain manag demograph clinic characterist associ perceiv patient famili engag associ perceiv patient famili engag patient outcom | D000701;D009293 | T121;T109;T131;T048 |
36,226,781 | prescrib pattern attitud primari care provid regard long term opioid therapi assess prescrib referr pattern attitud primari care provid treat patient receiv long term opioid therapi lot accord recent guidelin | D002047;D059350 | T121;T047;T109;T184 |
36,226,780 | opioid pain treatment cancer knowledg matur map conceptu structur opioid base bibliometr analysi articl web scienc use follow indic scienc citat index expand sci expand social scienc citat index ssci confer proceed citat index scienc cpci confer proceed citat index social scienc human cpci ssh book citat index scienc bkci book citat index social scienc human bkci ssh emerg sourc citat index esci construct analyz avail articl word opioid cancer show evolut state art countri treatment implement result process identifi cite articl extract main connect frequenc keyword author journal countri institut tendenc connect degre collabor tempor tendenc word cloud keyword network evolut word author product scientif product countri analyz term increas frequenc opioid employ treat cancer non cancer pain | D000701;D009369 | T121;T109;T131;T191 |
36,226,763 | direct cis hydrosilyl borylalkyn borylsilylalken hydrosilyl borylalkyn borylsilylalken differ arrang substitu success develop cis addit sih group cc bond direct use specif catalyst obtain product crucial synthon introduct cc bond organ synthesi | D002384 | T070 |
36,226,751 | new cu squar grid type ni ii triangl type complex synthesi character effect binder dna serum albumin multival molecul potenti group bioactiv compound endow high affin specif innov biomolecul target therapeut approach herein report new versatil n n n n donor ligand l r r n n bis quinolin ylmethylen cyclohexan diamin two coordin quinolin moieti connect tran diaminocyclohexan coordin cu form squar grid type complex c cu l ni give triangl type complex c ni l screen potenti versatil metal base serum albumin sa doubl helic g quadruplex dna binder take advantag shape size stabil effect use differ spectroscop experi uv vis fluoresc circular dichroism find work suggest potenti util metal complex herein describ context new drug discoveri | D056831;D011804 | T104;T109 |
36,226,747 | dual realist review compress leg swell end life potenti qualiti life benefit examin evid use compress general popul determin far use inform treatment end life | D011788;D007866 | T078;T023 |
36,226,744 | near infrar nir fluoresc emit small organ molecul cancer imag therapi near infrar nir fluorophor uniqu featur endow sever advantag convent shorter wavelength emit dye result wide util fluoresc photoacoust imag agent well photodynam phototherm therapeut agent howev non target nir fluoresc emit organ molecul drawback low select toward tumor potenti result sever side effect caus damag normal tissu thus develop nir fluorophor base substanc target tumor high activ area medicin chemistri research research effort carri thus far led develop number nir fluorophor base tumor imag therapeut agent discuss review focus result research report period give particular emphasi studi nir small organ dye base imag therapeut agent design util cancer select strategi | D009369 | T191 |
36,226,740 | light agricultur sustain new era nanozymolog overview classif agricultur applic concept sustain agricultur receiv increas attent humankind nanozym nanomateri enzym like activ higher environment endur longer term stabil natur enzym enabl agricultur technolog reform econom portabl benefit multipl catalyt activ renew nanocharacterist nanozym shine agricultur scenario use enzym engin nanosci act sustain toolbox improv agricultur product reduc risk agricultur system herein comprehens discuss classif nanozym appli current agricultur includ peroxidas like oxidas like catalas like superoxid dismutas like laccas like nanozym well biocatalyt mechan especi differ applic nanozym agricultur deepli review cover crop protect nutrit agroenvironment remedi monitor agroproduct qualiti monitor final challeng face nanozym agricultur applic propos expect review enhanc agricultur sustain nanozymolog | D042845;D049329 | T073;T126;T116 |
36,226,734 | gut microbiom overview current trend risk paediatr popul gut health increas popular topic discuss among scientist general popul alik interest surround gut microbiom grow access misinform unfound gut health trend youth like emerg public health concern purpos review provid paediatrician current inform gut microbiom well explan possibl risk multitud gut health trend adolesc may expos | D000069196;D064307;D044342 | T047;T007;T028;T001;T032 |
36,226,732 | pediatr strength train benefit concern current trend advent social media combin sever larg scale promot nationwid gym chain pediatr interest strength train reach new height past year healthi way young gym user build strength stay activ signific risk associ improp util exercis resourc lack adult supervis guidanc gym lead physic injuri inappropri use supplement bodi imag issu purpos review provid pediatrician date inform well toler exercis practic pubert prepubert youth | D055070 | T061 |
36,226,728 | character extrachromosom circular dna cattl use whole genom sequenc dataset extrachromosom circular dna eccdna import fraction genom recent studi prove eccdna play import role genet variat age environment adapt drawn wide attent howev characterist eccdna cattl remain unclear studi eccdna cattl breed use whole genom sequenc dataset total high confid eccdna identifi cover cattl autosom length similar speci cattl eccdna preferenti locat genic repeat sequenc cattl eccdna contain complet sequenc gene signific p enrich immun relat function eccdna prove invert repeat boundari contain high proport rang bp interest success separ anim accord geograph distribut tissu dna isol impli possibl role eccdna cattl select tissu develop studi suppli basic knowledg eccdna cattl promot understand extrachromosom dna | D004270;D002875 | T026;T123;T114 |
36,226,726 | femal pattern hair loss polycyst ovarian syndrom hirsut explor recent updat diagnosi manag clinic implic androgen alopecia among patient diagnos polycyst ovarian syndrom pcos | D011085;D017588;D007246 | T047;T046;T033 |
36,226,725 | prepar dibromo h inden tetrabromodihydro indacen synthet build block acid induc intramolecular cyclize disubstitut aryl dibromoallylalcohol afford dibromo h inden deriv method also applic prepar tetrabromodihydro indacen thus obtain multi bromin compound serv versatil synthet build block obtain varieti inden indacen deriv demonstr synthesi dialkylmethylen bridg oligo phenylenevinylen featur attract photophys properti | D007192 | T109 |
36,226,722 | mathemat model experiment valid extracellular vesicl mediat tumor suppressor microrna deliveri propag ovarian cancer cell extracellular vesicl ev mediat microrna transfer propag donor cell recipi cell tumor microenviron signific implic includ develop multidrug resist mdr although mirna encapsul ev shown function effect recipi cell quantit aspect transfer kinet function effect remain poor understood intracellular event degrad mirna load mirna ev cellular releas ev uptak recipi cell govern transfer function effect encapsul mirna base rate limit step develop mathemat model use ordinari differenti equat model perform cocultur experi use id vegf ovarian cancer cell demonstr ev mediat propag tumor suppressor mirna letb administ hyaluron acid poli ethyleneimin ha pei nanoparticl use experiment data model fit determin rate constant kinet event involv transfer donor cell recipi cell model perform letb transfect experi id vegf cell ha pei nanoparticl determin concentr effect relationship hmga mrna level last model combin model model paramet describ kinet effect relationship ev letb recipi cell predict minimum number mirna copi need show function effect | D035683;D000067128;D010051 | T191;T026;T123;T114 |
36,226,720 | qualiti safeti implement scienc acut kidney care qualiti safeti import theme acut kidney care akc mani recent initi highlight aspect howev becom part clinic practic rigor implement scienc methodolog must follow review present practic highlight recent initi acut kidney injuri aki kidney replac therapi krt recoveri aki | D000077626;D058186 | T090;T047;T037 |
36,226,716 | surg icu covid pandem overview coronavirus diseas covid pandem pose great challeng intens care unit icus across globe object review provid overview icu surg manag covid pandem special focus paper publish last month | D058873;D000086382 | T047;T067 |
36,226,713 | intens care manag liver transplant recipi liver transplant remain definit treatment advanc liver diseas liver failur current alloc scheme util liver transplant mandat sickest first approach thus liver transplant occur patient sever system ill intens care provid care liver transplant recipi foundat knowledg technic consider orthotop liver transplant basic manag consider common complic essenti review highlight author approach intens care manag postop liver transplant recipi review common issu aris patient popul | D016031;D017093;D008107 | T061;T047;T033 |
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