PMID
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35.7M
36.4M
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36,328,750
applic deep learn algorithm silico druggabl protein identif top prioriti drug develop identifi novel effect drug target vitro assay frequent use purpos howev tradit experiment approach insuffici larg scale explor novel drug target expens time consum labori therefor comput method emerg recent decad altern aid experiment...
D000077321
T066
36,328,749
metformin suppress vascular smooth muscl cell senesc promot autophag flux vascular smooth muscl cell vsmc senesc vasculatur result vascular age well age relat diseas metformin improv inflamm age profil enhanc autophagi howev metformin impact vsmc senesc larg undefin
D009131;D008687
T121;T024;T109
36,328,748
raman base spectrophenotyp import cell immun system human peripher blood mononuclear cell pbmcs heterogen popul cell includ b lymphocyt total number lymphocyt percentag blood marker diagnosi sever human diseas current cytometr method wide use distinguish subtyp leukocyt quantifi number techniqu use cell immunophenotyp ...
D007963;D008214
T025
36,328,747
conserv diverg regulatori network under reproduct branch rice maiz cereal crop major sourc raw food nutrit human worldwid infloresc cereal crop reproduct organ also contribut crop product branch pattern flower plant speci determin infloresc architectur also determin grain yield good review describ grass infloresc archi...
D012275
T168;T002
36,328,746
telnto assist precis target chromosom segment tape perform genom larg segment experi promot annot complex genom function contribut synthesi design genom challeng obtain manipul larg complex dna sequenc high effici
D004926;D002875
T026;T007
36,328,745
engin endogen hydrogen sulfid respons smart agent photoacoust imag guid combin phototherm therapi chemotherapi colon cancer phototherm therapi synergist combin chemotherapi improv therapeut effect colon cancer howev convent therapeut agent side effect normal tissu limit applic
D061088;D006862;D003474;D003110
T121;T109;T060;T131;T197;T191;T130
36,328,744
singl cell rna sequenc analysi reveal relationship bone marrow osteopenia stz induc type diabet mice type diabet td multifactori autoimmun diseas broad knowledg genet epidemiolog clinic manag td achiev understand cell varieti bone marrow td remain limit
D003922;D003921;D001851
T047;T050
36,328,743
long term exposur ambient adult mortal nationwid cohort studi china number popul base studi investig long term effect nitrogen dioxid mortal great heterogen exist studi high popul countri asia cohort evid mortal associ extens spars
D009585;D000397
T131;T197;T069;T080
36,328,742
guard food safeti convent convers near infrar fluoresc sensor acknowledg world health organis diseas rang mild fatal link consumpt food product subject physic chemic biolog contamin nevertheless convent method common use identif health hazard foodstuff problem cope sensit requir impos latest hour regul field addit use ...
D059022;D009183
T131;T109;T057
36,328,741
mscs odn load exosom immunomodulatori reveal proteom cargo sustain wound resolut non heal wound remain major burden due lack effect treatment mesenchym stem cell deriv exosom msc exo emerg therapeut option given pro regen immunomodulatori featur still littl known exact mechan mediat msc exo import modul efficaci physio...
D055354
T026
36,328,740
structur optim honeycomb scaffold outstand abil vertic bone augment case intract dental implant requir vertic bone augment howev predict bone height volum difficult obtain vertic bone augment contact surfac scaffold bone limit bottom face scaffold furthermor strength decreas caus scaffold resorpt lead collaps augment s...
D000540
T061
36,328,739
ubiquitin specif proteas antagon melatonin induc endocyt degrad mt receptor promot lung adenocarcinoma growth human genom encod two melatonin receptor mt mt relay melatonin signal cellular interior accumul evid link melatonin multipl health benefit among anticanc effect becom well establish howev implic receptor lung a...
D008550;D000077192;D000230;D008175
T125;T121;T191;T109
36,328,731
use electromagnet field microbi process bioengin electromagnet field emf shown various stimulatori inhibitori effect microorgan year grow interest topic led numer discoveri suggest potenti applic emf biotechnolog process among observ stimul effect physic influenc result intensifi biomass product modif metabol activ pig...
D004574;D058086
T070;T204
36,328,730
role psychrotroph bacteria cold activ enzym compost method adopt cold region temperatur depend compost challeng task worthi done right manner cold compost known practic sinc ancient time enough advanc overcom long mesophil phase bring compost matur short period compost process well practic discuss role psychrotroph bac...
D000076282
T068;T167
36,328,728
aiee activ sensor fluoresc enhanc base detect ni live cell mechanofluorochrom photochrom properti revers sens acid base stimuli respons sensor qi qi ration develop exhibit divers featur mutabl mechanofluorochrom revers photochrom solvatochrom aggreg induc emiss enhanc aiee metal ion sens observ except structur properti...
D003124;D008128
T078;T059
36,328,727
mxene novel cartridg n glycan enrich studi appli mxene column cartridg n glycan enrich human sampl focus analysi sialic acid linkag use derivatis protocol follow glycan analysi via matrix assist laser desorpt ionis time flight mass spectrometri maldi tof ms mxene base cartridg enrich higher number glycan ie sialyl bise...
D011134;D019158
T121;T123;T109
36,328,726
bioanalyt method encompass label free label tuberculosi aptasensor review high incid tuberculosi tb infect great concern world wide tradit tb diagnost techniqu ideal tb diagnosi resourc poor countri due high complex expens natur long time durat poor sensit specif well requir sophist laboratori special biosafeti condit ...
D052157;D014376;D015374;D009169;D049329
T007;T073;T075;T059;T114;T047
36,328,725
one click investig shape influenc silver nanostructur ser perform sensit detect covid sensit accur detect sar cov method meaning prevent control novel coronavirus detect techniqu support portabl onsit time onlin data transfer urgent need one click investig shape influenc silver nanostructur ser perform applic sensit de...
D000086382;D049329;D053768
T047;T073;T067
36,328,724
high sensit sar cov detect use graphen oxid multiplex qpcr emerg pandem sever acut respiratori syndrom coronavirus sar cov critic challeng earli accur virus diagnos howev current gold standard sar cov detect revers transcript quantit polymeras chain reaction rt qpcr report fail detect low viral load one compound graphe...
D000086402;D000086382
T005;T067;T047
36,328,723
construct destruct gold nanoparticl assembl liquid liquid interfac cd sens analyt induc aggreg plasmon nanoparticl nps bulk solut wide employ optic sensor howev trace detect slow diffus kinet nps ultralow concentr analyt signific limit bind opportun analyt thus impos penalti sensit reproduc respons time sensor herein p...
D006046;D053768
T121;T196;T073
36,328,722
enzym base amperometr biosensor year later quo vadi enzym base amperometr biosensor repres power tool remot medicin situ analysi nowaday billion peopl surround enzym base amperometr biosensor even consid relat young age year period mani research deal most target molecul earli time develop novel strategi tackl electron ...
D015374
T059;T075
36,328,721
rapid determin sar cov nucleocapsid protein base dd mxenep bioclru bpi heterojunct composit enhanc electrochemiluminesc perform end novel coronavirus diseas covid cluster atyp pneumonia caus sever acut respiratori syndrom coronavirus sar cov known high contagi diseas herein report mxenep bioclru bpi heterojunct composi...
D015374;D000086382
T047;T067;T059;T075
36,328,720
facil one step synthesi graphen oxidepolyhedr oligomer silsesquioxan composit coat fiber high effici solid phase microextract polycycl musk effici fabric excel fiber coat high perform solid phase microextract spme interest high effici synthesi strategi graphen oxidepolyhedr oligomer silsesquioxan goposs composit coat f...
D052617;D006108
T196;T059;T109
36,328,719
evolut natur dihydroptero synthas develop signal amplifi fluoresc method detect sulfonamid milk studi recognit mechan affin natur dihydroptero synthas sulfonamid studi respect key contact amino acid ser mutat arg use site direct mutagenesi method produc mutant result show bind energi affin drug general improv mutant us...
D004094;D008892
T168;T126;T116;T031
36,328,718
review develop applic surfac molecular imprint polym toward amino acid peptid protein molecular imprint polym mip receiv wide interest bioanalysi field artifici antibodi mimic biolog receptor select recogn adsorb target molecul owe specif affin target tradit mip obtain bulk imprint defect includ low adsorpt capac poor ...
D054802
T063
36,328,717
recent advanc airborn pathogen detect use optic electrochem biosensor world current face advers condit due pandem airborn pathogen sar cov prevent better cure thus rapid detect airborn pathogen necessari reduc outbreak save mani live consid immens role divers detect techniqu airborn pathogen proper summar techniqu woul...
D000086382;D015374
T075;T047;T059;T067
36,328,716
metal organ framework separ review possibl design high permeabl select metal organ framework mof design function larg number possibl mof structur permut aris consider number possibl metal node great varieti organ ligand use materi herein discuss applic mof manner separ includ gas adsorptionsepar membran gas chromatogra...
D000073396
T109
36,328,715
review chromatograph specif detect methodolog unravel complex moah food contamin food miner oil hydrocarbon particular miner oil aromat hydrocarbon moah potenti pose health hazard consum howev identifi toxic substanc among mani thousand compound compris miner oil food sampl difficult analyt challeng accord european foo...
D008899;D006841
T121;T109
36,328,706
orexin reserv mechanist framework role orexin hypocretin addict propos orexin signal transform motiv relev state adapt behavior direct toward exploit opportun manag threat process refer motiv activ advanc anim model sinc permit higher resolut measur motiv state particular behavior econom approach studi drug demand char...
D009479;D016739
T123;T116;T048
36,328,694
coronari arteri bypass surgeri without saphen vein graft jacc review topic week approxim patient age undergo contemporari coronari bypass surgeri receiv least saphen vein graft svg recogn svg develop progress acceler atherosclerosi result stenosi occlus occur year postop arteri conduit littl evid progress failur svg co...
D012501;D001026
T061;T023
36,328,690
risk factor hospit cardiac arrest patient st segment elev myocardi infarct hospit cardiac arrest ihca one deleteri complic st segment elev myocardi infarct stemi
D000072657;D054058;D062645;D058687
T061;T047;T046
36,328,672
xpm enhanc exogen data visibl process mine well establish disciplin applic mani industri sector includ healthcar date public consid context process execut littl consider given contextu data exogen data practic includ process mine analysi beyond includ case event attribut typic event log show combin process data endogen...
D003695;D057225
T058;T066;T093
36,328,671
cyclegan virtual stain transfer see realli believ digit patholog area prone high variat due multipl factor strong affect diagnost qualiti visual appear whole slide imag wsis state art method deal variat tend address style transfer inspir approach usual solut direct appli success approach literatur potenti task relat mo...
D004396;D007091
T197;T130;T066;T109
36,328,670
cardiac anomali detect consid addit nois convolut distort model heart sound record cardiac auscult essenti point care method use earli diagnosi heart diseas automat analysi heart sound abnorm detect face challeng addit nois sensor depend degrad paper aim develop method address cardiac abnorm detect problem compon prese...
D012815;D006347
T066;T042
36,328,669
manifesto explain artifici intellig medicin rapid increas interest use artifici intellig ai comput applic rais parallel concern abil lack thereof provid understand explain output user concern especi legitim biomed context patient safeti paramount import posit paper bring togeth seven research work field differ role per...
D001185;D008511
T090;T091;T073;T066
36,328,668
tempor deep learn framework retinopathi predict patient type diabet adopt electron health record hospit ensur avail larg dataset use predict medic complic trajectori patient real world set high variabl make longitudin data model challeng recent year signific progress made studi deep learn model appli time seri howev ap...
D000077321;D003922;D012164
T047;T066
36,328,667
weak supervis learn use attent gate colon cancer histopatholog imag segment recent artifici intellig name deep learn method revolution wide rang domain applic besid digit patholog far play major role diagnosi prognosi tumor howev characterist whole slide imag name gigapixel size high resolut shortag rich label sampl hi...
D007091;D003110
T191;T066
36,328,666
evolutionari optimis antibiot dose regimen bacteria differ level resist antimicrobi resist one biggest threat global health food secur develop antibiot overus misus main driver emerg resist crucial optimis use exist antibiot order improv medic outcom decreas toxic reduc emerg resist formul design antibiot dose regimen ...
D000900;D001424
T121;T047;T195
36,328,655
finerenon heart failur outcom kidney functionalbuminuria chronic kidney diseas diabet patient type diabet td risk cardiovascular mortal heart failur hf increas decreas kidney function estim glomerular filtrat rate egfr increas albuminuria urin albumin creatinin ratio uacr finerenon select nonsteroid mineralocorticoid r...
D003924;D006333;D051436
T047;T046
36,328,654
trend heart failur relat mortal among older adult unit state us popul age concurr increas heart failur hf burden howev hf relat mortal trend among adult year investig
D006333
T047;T046
36,328,653
steroid mra across spectrum renal function pool analysi rcts mineralocorticoid receptor antagonist mras underus patient kidney dysfunct efficaci among patient chronic kidney diseas ckd uncertain
D006947;D006333;D051436
T033;T047;T046
36,328,651
posterior wall thick associ surviv follow septal myectomi obstruct hypertroph cardiomyopathi left ventricular lv posterior wall thick pwt predictor sudden cardiac death pediatr patient hypertroph cardiomyopathi hcm prognost import pwt adult examin
D006333;D002312
T047;T046
36,328,649
risk depress suicid diagnosi heart failur nation cohort studi heart failur hf associ psychosoci distress long term mental health sequela unclear
D006333;D013405
T033;T047;T046
36,328,647
trend ischem evalu new onset heart failur without known coronari arteri diseas guidelin recommend consider ischem evalu class iia iib new onset heart failur hf well known often perform lead revascular
D003324;D006333;D062645
T061;T047;T046
36,328,645
famili screen dilat cardiomyopathi preval incid potenti limit follow accord pattern inherit incomplet penetr fewer half relat dilat cardiomyopathi proband develop diseas
D002311;D006333
T047;T046
36,328,644
retin microvasculatur potenti window heart failur prevent endotheli dysfunct microvascular diseas shown play import role develop progress heart failur hf retin imag provid uniqu opportun noninvas assess vascular structur function vessel featur microcircul within retina accumul evid suggest retin vessel calib microvascu...
D006333
T047;T046
36,328,636
support care patient critic coronavirus diseas specif therapi treatment coronavirus diseas covid limit efficaci event patient worsen clinic requir admiss intens care unit icu thus provid qualiti support care essenti overal manag patient critic covid patient respiratori failur requir intub support noninvas posit pressur...
D000086382;D063087;D012131
T061;T047;T046;T067
36,328,635
manag sever critic covid infect immunotherapi follow reduct mortal demonstr dexamethason treatment sever covid mani target immunotherapi investig thus far inhibit il jak pathway robust data grant emerg use author treatment sever diseas howev must note critic ill patient compris relat small proport trial covid therapeut...
D000086382
T047;T067
36,328,628
critic care vascular surgeri patient patient requir major vascular surgeri suffer widespread atherosclerosi multipl comorbid place increas risk postop complic requir admiss intens care unit icu postop critic care patient focus hemodynam optim earli identif manag complic improv outcom
D003422;D007362
T058;T073;T093
36,328,626
unstabl carotid plaqu carotid revascular perform prevent cerebrovascular event patient symptomat asymptomat high degre carotid stenosi oper carri signific risk periop stroke care select patient benefit procedur essenti certain plaqu characterist includ textur associ increas tendenc ruptur use identifi high risk patient...
D016894;D016893;D020521;D000765
T061;T047;T020
36,328,625
anesthet manag endovascular repair thorac abdomin aortic aneurysm aortic aneurysm abdomin thorac signific caus death disabl unit state endovascular aneurysm repair sinc becom prefer oper treatment thorac abdomin aneurysm lower rate complic better outcom compar open approach patient present endovascular aneurysm repair ...
D017544;D019917;D057510;D000777
T061;T121;T047;T039
36,328,622
thorac thoracoabdomin aneurysm etiolog epidemiolog natur histori thorac aortic aneurysm thoracoabdomin aneurysm often found incident complic includ dissect ruptur thorac aortic aneurysm thoracoabdomin aneurysm develop patient risk factor atherosclerosi younger patient without signific cardiovascular risk factor may gen...
D017545;D000784;D008382;D006349
T047;T046
36,328,621
abdomin aortic aneurysm etiolog epidemiolog natur histori abdomin aortic aneurysm potenti lethal condit decreas frequenc tobacco use declin exact etiolog remain unknown smoke perturb seem trigger inflammatori state tunica media male sex advanc age clear demograph risk factor develop abdomin aortic aneurysm natur histor...
D017544;D001019
T047
36,328,620
monitor vascular surgeri vascular surgic patient present uniqu challeng anesthesiologist medic vulner well tendenc rapid intraop hemodynam chang intraop monitor use decad reduc advers outcom improv mortal creat optim surgic condit understand indic appropri manag monitor modal essenti optim patient care prevent harm ass...
D016343;D014656
T060;T061
36,328,617
complic vascular diseas vascular diseas sequela increas periop risk noncardiac surgic patient review author discuss vascular diseas epidemiolog pathophysiolog risk stratif manag strategi reduc advers periop outcom
D011183;D014652
T047;T046
36,328,616
preoper evalu cardiac risk assess vascular surgeri summar epidemiolog trend outcom preoper guidelin vascular surgeri patient vascular surgeri continu evolv technolog engin treat surgic popul suffer high preval comorbid preoper optim seek character burden diseas achiev medic control timelin avail surgeri risk assess eva...
D011300;D000073496
T033;T184;T058;T046
36,328,612
advanc treatment neonat biliari diseas articl discuss current standard care neonat biliari diseas particular manag biliari atresia choledoch cyst highlight surgic consider guidelin adjuv therapi promis therapeut option investig
D015529;D001656;D007232
T019;T047
36,328,611
advanc manag neonat born anorect malform anorect malform occur children present mark varieti type sever malform diagnos earli neonat period antenat diagnosi remain relat elus follow diagnosi accur assess focus manag crucial reduc potenti morbid mortal review focus investig manag newborn anorect malform introduct novel ...
D000071056
T019;T190
36,328,610
review necrot enterocol spontan intestin perfor clinic present treatment outcom necrot enterocol surgeri trial nest highlight import distinguish necrot enterocol nec spontan intestin perfor sip develop surgic treatment plan research need increas accuraci distinct even current abil initi laparotomi appear optim infant p...
D020345;D007416;D007235;D007232
T047
36,328,609
abdomin wall defect review current practic guidelin common congenit abdomin wall defect gastroschisi omphalocel gastroschisi defect abdomin wall expos abdomin content mortal rate low length stay often prolong bowel dysmotil intestin abnorm complic case omphalocel defect umbil cord herniat abdomin content cover sac asso...
D020139;D006554;D034861
T019;T047;T023
36,328,606
surgic manag congenit diaphragmat hernia congenit diaphragmat hernia cdh challeng surgic diseas requir complex preoper periop postop care surviv depend success reduct repair defect numer complex decis must made regard time prepar surgeri review describ challeng controversi inher surgic cdh care provid recommend manag b...
D065630;D015199
T061;T019
36,328,604
utero therapi congenit diaphragmat hernia congenit diaphragmat hernia anomali often prenat diagnos span wide spectrum diseas high morbid mortal associ fetus sever defect congenit diaphragmat hernia thus ideal target fetal intervent review literatur prenat diagnosi describ histori fetal intervent congenit diaphragmat he...
D065630;D005315;D046128
T061;T019;T047
36,328,603
fetal therapi renal anhydramnio sever form congenit anomali kidney urinari tract present fetal life earli pregnanc renal anhydramnio consid lethal due pulmonari hypoplasia without fetal therapi due high rate addit structur anomali genet abnorm associ syndrom detail anatom survey genet test imper stratifi pregnanc appro...
D016104;D046128
T061;T046
36,328,602
fetal repair neural tube defect myelomeningocel common congenit neurolog defect nonleth diseas address fetal surgeri random control trial establish amelior arnold chiari ii malform reduc ventriculoperiton shunt rate improv distal neurolog function patient receiv utero repair long term follow school age children demonst...
D008591;D009436;D046128
T061;T019;T047;T020
36,328,600
molecular cellular utero therapi signific advanc matern fetal medicin gene sequenc technolog foster new frontier utero molecular cellular therapeut includ gene edit enzym replac therapi stem cell transplant treat singl gene disord limit postnat treatment strategi utero therapi take advantag uniqu development properti f...
D046128;D018380
T061
36,328,599
rear matern fetal surgeri matur field concept adulthood matern fetal surgeri fraught inher controversi within medic communiti general public despit challeng field matern fetal surgeri evolv intern enterpris care nurtur pioneer foresight resili field navig ethic dilemma rigor scientif methodolog collabor transpar accord...
D004992;D046128
T078;T061
36,328,595
myeloma immunoglobulin rearrang transloc detect target captur sequenc multipl myeloma plasma cell neoplasm character clonal immunoglobulin v j signatur oncogen immunoglobulin gene transloc addit subclon genom chang acquir myeloma progress therapeut select pcr base method detect v j rearrang bias introduc high multiplex...
D009101
T191
36,328,587
ultra magnifi imag thoracoscop biopsi specimen use ex vivo endocytoscopi three patient mesothelioma perform endocytoscopi ec ex vivo evalu mesothelioma specimen biopsi medic thoracoscopi three patient evalu biopsi specimen base densiti nuclei irregular nuclei shape use ec compar histopatholog find specimen consid malig...
D008654;D000086002;D010997
T191
36,328,586
endoscop submucos dissect improv bloodi stool associ polypoid type mucos prolaps syndrom case seri mucos prolaps syndrom mps benign inflammatori diseas rectum caus bloodi stool endoscop treatment mps establish herein report consecut case seri endoscop submucos dissect esd mps four case treat esd alon lesion dentat line...
D000069916
T061
36,328,585
reduc rate diseas flare japanes patient system lupus erythematosus alter balanc use glucocorticoid immunosuppress recent decad object studi examin whether diseas control japanes patient system lupus erythematosus sle improv recent year possibl associ alter balanc use glucocorticoid immunosuppress method enrol japanes p...
D005938;D008180
T125;T047;T039;T109
36,328,584
differ prognost factor among patient hospit heart failur accord age categori kuniumi registri acut cohort object previous studi describ sever prognost factor heart failur hf howev result deriv registri consist convent age group might repres increas age societi present studi explor prognost factor caus death hospit pati...
D001281;D000073496;D006333
T033;T184;T047;T046
36,328,583
assess carotid atherosclerot plaqu among young patient famili hypercholesterolemia object data exist regard atherosclerot chang occur among patient famili hypercholesterolemia fh carotid ultrasonographi non invas method evalu issu present studi compar clinic util carotid intima media thick cimt carotid plaqu score cps ...
D058226;D006938;D002340
T047;T046;T020;T031
36,328,582
factor contribut prognosi second line therapi ramucirumab advanc hepatocellular carcinoma object multipl therapeut agent exist advanc hepatocellular carcinoma hcc prognost factor second line subsequ therapi unclear ramucirumab molecular target agent effect hepatocyt alpha fetoprotein afp ngml sorafenib failur examin pr...
D006528;D008113
T191
36,328,541
clinicopatholog immunophenotyp featur dog presumpt larg granular lymphocyt leukaemia larg granular lymphocyt leukaemia lgll describ rang speci common report human dog speci neoplasia exhibit divers phenotyp biolog behaviour phenotyp partial predict behaviour current littl knowledg concurr haematolog serum biochemistri ...
D054066;D004283
T047;T191
36,328,540
effici correct pcr quantif identif preval load respiratori diseas caus agent feedlot cattl bovin respiratori diseas brd preval diseas feedlot cattl worldwid bovin alphaherpesvirus boahv histophilus somni mannheimia haemolytica mycoplasma bovi pasteurella multocida trueperella pyogen accept common etiolog agent associ b...
D016978;D002418;D048090
T047;T007
36,328,470
e cigarett tobacco product use among nys youth state wide vape flavour restrict polici reduc youth e cigarett use new york state nys public health prioriti may state wide restrict flavour e cigarett except tobacco flavour pass studi examin chang nicotin product use behaviour among youth around time state wide vape flav...
D000072137;D066300;D014029;D062789
T073;T109;T055;T131;T048
36,328,469
remov mango flavour juul pod creat opportun adulter mango juul compat pod alter chemic constitu juul lead electron cigarett e cigarett brand usa novemb juul pre emptiv limit onlin store sale non tobacco menthol flavour pod ahead impend flavour ban sinc remov sale mango flavour juul compat pod introduc market smaller co...
D066300;D031022;D000072137;D062789
T073;T109;T168;T055;T131;T002
36,328,467
chang product label practic use flavour chemic addit vape product enact statewid flavour legisl may new york state enact legisl ban sale vape product distinguish flavour tobacco accord new statut vape product deem flavour includ statement whether express impli distinguish tast aroma tobacco studi aim determin manufactu...
D000072137;D062789;D066300
T055;T073;T131;T109
36,328,466
electron nicotin deliveri system end flavour devic use adult us fda end enforc prioriti find us itc smoke vape survey februari us food drug administr fda prioritis enforc effort flavour prefil cartridgepod electron nicotin deliveri system end except tobacco menthol studi examin chang preprior enforc earli postenforc fe...
D000072137;D066300;D062789
T055;T073;T131;T109
36,328,465
examin associ e cigarett flavour restrict e cigarett use success quit smoke among us adult restrict avail e cigarett flavour tobacco menthol may reduc appeal among youth unknown flavour restrict impact adult use e cigarett quit smoke cigarett
D066300;D000072137;D016540
T055;T073
36,328,464
industri respons strengthen regul amount theme flavour electron cigarett promot product vendor manufactur instagram social media discuss tend follow news propos enact govern polici thus digit discours surveil may effect unobtrus way understand industri public respons polici regul includ domain tobacco control recent us...
D066300;D062789;D000072137;D061108
T073;T109;T131;T055;T170
36,328,463
associ live local e cigarett sale restrict e cigarett use chang among young adult los angel counti local e cigarett sale restrict esr may impact e cigarett use studi examin associ live local various esr polici chang e cigarett use among young adult los angel la counti california usa
D066300;D000072137;D062789;D000073865
T055;T073;T131;T109
36,328,462
flavour loyalti may predict cessat substitut follow cigarillo flavour ban among young adult usa purpos research measur flavour loyalti identifi current cigarillo user may respond hypothet flavour ban usa
D062789;D014029
T131;T048;T073;T109
36,328,461
illeg experiment tobacco marketplac ii effect vape product ban find intern tobacco control project restrict e cigarett polici may increas purchas illeg sourc illeg experiment tobacco marketplac ietm allow examin restrict impact illeg purchas investig effect vape ban total flavour vape ban partial flavour vape ban proba...
D000072137;D066300;D062789
T055;T073;T131;T109
36,328,460
ethyl maltol vanillin corylon convent confectioneri relat flavour chemic domin e cigarett liquid label tobacco flavour increas popular electron cigarett e cigarett link abund flavour product attract adolesc young adult last decad e cigarett design evolv four generat includ modif batteri power e cigarett liquid e liquid...
D066300;D062789
T131;T073;T109
36,328,459
electron cigarett user reaction respons hypothet ban flavour electron cigarett liquid backgroundregul propos limit e cigarett flavour limit research examin potenti impact polici studi examin adult e cigarett user reaction hypothet e cigarett flavour ban
D066300;D000072137;D062789
T055;T073;T131;T109
36,328,458
juul alter content menthol pod respons us fda flavour enforc polici juul electron cigarett e cigarett remain popular usa big preval among youth respons popular juul similar devic among youth us food drug administr issu februari enforc polici remov flavour cartridgepod base e cigarett market except tobacco menthol subse...
D066300;D062789;D000072137
T131;T073;T055;T109
36,328,457
impact fda flavour enforc polici flavour electron cigarett use behaviour chang studi aim investig electron cigarett e cigarett use behaviour chang implement us food drug administr fda restrict sale unauthoris flavour cartridg base e cigarett tobacco menthol flavour februari well factor associ chang
D066300;D000072137;D062789
T055;T073;T131;T109
36,328,456
assess toxic emiss e liquid diy addit use respons potenti flavour ban e cigarett electron cigarett e cigarett aerosolis liquid contain nicotin propylen glycol glycerol appeal flavour usa regul limit avail flavour e cigarett pod base system tighten expect respons e cigarett user may attempt make e liquid diy studi exami...
D066300
T073
36,328,435
role red blood cell immun respons infect review red blood cell largest number cell blood apart transport oxygen carbon dioxid also regul immun respons confirm red blood cell play role clear immun complex promot phagocytosi present antigen immun adhesionthey also regul immun respons particip oxid stress interact lymphoc...
D010587;D008214
T025;T043
36,328,434
regul pd l posttransl modif applic progress tumor immunotherapi immun checkpoint program death ligand program death pd lpd one promis target tumor immunotherapi overexpress pd l surfac tumor cell could bind pd surfac cell inhibit cell activ trigger tumor immun escap therapeut strategi target pd pd l restor cytotox func...
D060890;D009369
T129;T191;T116
36,328,433
prokaryot express prostat specif membran antigen psma nanoantibodi gene screen natur phage nanoantibodi librari object screen nanobodi prostat specif membran antigen psma method base naiv phage display librari three round screen perform target psma antigen posit clone identifi elisa sequenc perform posit clone gene seq...
D061905;D001435
T129;T005;T116
36,328,432
unsatur fatti acid actinidia chinesi planch seed oil protect pulmonari fibrosi inhibit collagen synthesi via regul connect tissu growth factor ctgf express rat object observ role connect tissu growth factor ctgf collagen synthesi anti pulmonari fibrosi pf kiwi fruit essenc unsatur fatti acid actinidia chinesi planch se...
D029042;D011658;D009822
T047;T002;T109
36,328,431
silenc circular rna embryon lethal abnorm vision like protein circelavl inhibit prolifer induc apoptosi mous testicular tm sertoli cell object investig effect silenc circular rnaembryon lethal abnorm vision like protein circelavl mmucirc prolifer apoptosi mous testicular tm sertoli cell identifi under mechan method sma...
D000079962;D035683
T123;T114
36,328,430
regul mir inhibit mitochondri fusion fission rat hc cardiomyocyt induc oxygen glucos deprivationreoxygen object investig effect mir interfer mitochondri fusion fission cardiomyocyt induc oxygen glucos deprivationreoxygen ogdr method hc cell divid normal control group model group negat control group mir interfer group r...
D032383;D035683
T123;T025;T114
36,328,429
wnta activ jnk promot prolifer autophagi kgn human granulosa cell object investig effect wnta autophagi kgn human granulosa cell method kgn human granulosa cell treat dmso control group recombin wnta protein rwnta wnta inhibitor iwp box separ express level wnta protein detect western blot co local wnta protein forkhead...
D001343;D006107
T025;T043
36,328,428
eukaryot express human box bind protein yb promot prolifer migrat human hepg cell object establish eukaryot express vector box bind protein yb flag tag transfect hepatocellular carcinoma hepg cell identifi effect yb prolifer migrat method human yb gene amplifi human ovari librari pcr yb fraction doubl enzym digest conn...
D051840;D056890
T123;T116;T204
36,328,427
astragalosid iv inhibit oxid stress mediat apoptosi human syy cell activ nrf ho signal pathway object investig protect effect mechan astragalosid iv ast h induc oxid stress injuri apoptosi syy cell method human syy cell cultur vitro induc h establish oxid stress model divid pbs group h group ast group cell viabil deter...
D051267;D006861
T123;T121;T116;T197;T130
36,328,426
block connexin inhibit polar mous macrophag induc lipopolysaccharid object investig effect connexin cx polar mous raw macrophag induc lipopolysaccharid lps method raw macrophag cultur vitro random divid four group control group lps group lps combin gap group lps combin gap group protein level cx polar marker cd induc n...
D008070;D018031
T123;T116;T109
36,328,425
tolerogen dendrit cell form microchimer vivo collagen induc arthriti rat object find evid microchimer format follow infus tolerogen dendrit cell tdcs collagen induc arthriti cia rat method bone marrow deriv dc precursor cell induc tdcs granulocyt macrophag coloni stimul factor gm csf interleukin il nuclear factor b oli...
D001169
T050