PMID
int64 35.7M
36.4M
| Title/Abstract
stringlengths 22
8.78k
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101
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stringlengths 4
64
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|---|---|---|---|
36,326,329
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morphometr analysi hippocampus intracrani format base stage patient diagnos major cognit disord alzheim diseas ad major cognit disord classifi common type dementia magnet reson imag mri practic method diagnost purpos ad aim studi determin volum hippocampus intracrani structur ad use mri
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D000544;D060825
|
T047;T048
|
36,326,328
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effect supervis group exercis therapi base biopsychosoci model introduc simultan anti tnf therapi anti tnf naiv patient activ ankylos spondyl studi aim investig effect supervis group exercis therapi base biopsychosoci model introduc simultan antitumor necrosi factor tnf therapi anti tnf naiv patient activ ankylos spondyl
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D013167
|
T047
|
36,326,327
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comparison geriatr nutrit risk index creatinin index short term mortal predict mainten hemodialysi patient aim studi analyz compar predict valu geriatr nutrit risk index gnri creatinin index ci short term mortal mainten hemodialysi patient determin best cut off
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D015596;D009752
|
T060;T081;T170;T033
|
36,326,325
|
devic facilit screw appropri angl quadrilater surfac fractur degre drill attach within studi aim investig radiolog function outcom acetabular fractur involv quadrilater surfac use drill attach anterior intrapelv approach
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D006620;D016103
|
T037
|
36,326,324
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effect iron defici left ventricular function young women regardless anemia speckl track echocardiographi studi iron defici one common metabol disord worldwid affect multipl organ system includ cardiovascular cv system iron defici caus structur function chang myocardium aim studi evalu left ventricular lv function patient low ferritin level without anemia two dimension speckl track echocardiographi ste
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D000090463;D000740
|
T047
|
36,326,323
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turkey transit face face school covid pandem covid pandem major disrupt convent school mani countri maintain educ servic distanc educ durat school closur turkey longer oecd countri thus turkey priorit school reopen academ year mitig possibl negat outcom closur studi compat implic school reopen turkey practic assess first semest face face school
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D000086382;D058873;D012574
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T092;T047;T073;T067
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36,326,322
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classic heart rate variabl nonlinear heart rate analysi mice napentobarbit ketaminexylazin anesthesia anesthet often use anim experi achiev immobil reliev pain howev mani anesthet alter dynam cardiovascular system aim compar effect two frequent use anesthet agent heart rate variabl hrv paramet mice
|
D007649;D000758;D000777
|
T061;T121;T039;T109
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36,326,321
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ten year outcom patient develop persist azoospermia follow chemotherapi associ differ oncolog diagnos retrospect cohort studi differ perspect studi evalu treatment procedur chemotherapi ct induc persist azoospermia outcom differ perspect
|
D053713
|
T047
|
36,326,320
|
relationship elev plasma zonulin level hashimoto thyroid hashimoto thyroid ht one preval autoimmun diseas intestin microbiota strong associ autoimmun diseas zonulin modul tight junction control select permeabl intestin induc elev gut permeabl aim investig associ plasma zonulin level ht
|
D050031;D000069196;D001327
|
T047;T007;T001
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36,326,319
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paraoxonas fetuin level children cerebr palsi studi most focus risk factor clinic status children cerebr palsi cp various antiinflammatori marker may help us earli diagnosi clinic classif cerebr palsi patient studi relationship antiinflammatori marker level clinic status patient cp determin first time fetuin paraoxonas pon examin children cp
|
D002547
|
T019;T047
|
36,326,318
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memantin show chemoprevent effect mice breast tumor model cancer cell express higher level n methyl aspart nmda receptor studi aim use memantin potenti blocker inhibit action nmda receptor cancer cell vivo order investig potenti chemoprevent effect memantin tumor bear mice
|
D008559;D015850
|
T129;T121;T116;T109
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36,326,316
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investig mirna cytokin express latent tuberculosi infect activ tuberculosi tuberculsosi tb mirna use biomark distinguish healthi individu tb patient aim studi investig associ mirna cytokin express level cours tuberculosi infect clinic form respons treatment ii effect genotyp featur bacteria cours tuberculosi relationship mirna cytokin express bacteri genotyp
|
D055985;D035683;D014376;D009169
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T123;T047;T007;T114
|
36,326,315
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risk cancer patient primari sjgren syndrom singl center studi turkey aim studi determin risk cancer patient primari sjgren syndrom pss singl center turkey
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D012859;D009369;D008228;D001943;D019337;D010051
|
T047;T191
|
36,326,314
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determin mirna express profil patient prostat cancer benign prostat hyperplasia known fact role microrna mirna import place cancer develop progress mirna target signific part pathway well gene studi aim compar differenti express profil mirna prostat cancer benign prostat hyperplasia patient
|
D011470;D011471;D035683
|
T123;T047;T191;T114
|
36,326,313
|
test retest reliabl minim detect chang measur wearabl gait analysi system g walk children cerebr palsi cerebr palsi cp frequent caus physic disabl childhood cp caus primari deficit impair muscl tone muscl weak problem select motor control secondari deficit contractur deform deficit lead motor disord movement caus limit gait sixti percent children cp walk independ despit problem howev present various gait abnorm gait analysi use quantit assess gait disturb provid function diagnosi assess treatment plan monitor progress g walk wearabl sensor devic provid quantit gait analysi via spatiotempor paramet pelvic girdl angl literatur studi investig reliabl g walk children cp purpos studi confirm test retest reliabl commerci avail bodi worn sensor bts g walk sensor system spatiotempor gait paramet children cp
|
D002547;D000076251
|
T019;T047;T073
|
36,326,312
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radiom analysi uterin tumor f fluorodeoxyglucos positron emiss tomographi predict lymph node metastas endometri carcinoma singl center studi aim analyz textur featur primari uterin lesion f fdg petct predict lymph node metastas
|
D016889;D014594
|
T191
|
36,326,311
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reflux dysphonia dysphagia symptom patient diabet associ diabet complic diabet mellitus dm could influenc various organ especi eye kidney nerv heart blood vessel final result mani irrevers diseas relat complic paper associ reflux swallow voic symptom patient dm possibl effect diabet complic symptom investig
|
D055154;D003680;D048909;D003920
|
T184;T047;T048
|
36,326,310
|
arthroscop bankart repair improv upper limb exercis capac shoulder function qualiti life anterior glenohumer instabl import caus shoulder disabl aim present studi investig arm exercis capac patient anterior glenohumer instabl arthroscop bankart repair compar result healthi control
|
D007593;D012785
|
T033;T023;T030
|
36,326,309
|
efficaci anakinra compar standard care treatment covid meta analysi sar cov continu spread worldwid studi bring light link anakinra recombin il receptor antagonist avert grave clinic outcom object meta analysi investig effect anakinra intervent group compar controlstandard care group mortal along provis preval estim variabl associ death c reactiv protein crp ferritin acut respiratori distress syndrom ard
|
D000086382;D012128
|
T047;T067
|
36,326,308
|
analges efficaci ultrasound guid unilater erector spina plane block laparoscop inguin hernia repair random control studi although laparoscop inguin herniorrhaphi associ faster return daili activ inadequ postop pain control caus prolong hospit stay patient discomfort erector spina plane block esp administ postop pain manag abdomin thorac surgeri investig effect unilater esp block applic laparoscop hernia surgeri
|
D009407;D006552;D010535
|
T061;T060;T047;T190
|
36,326,307
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applic high flow oxygen therapi acut pancreat complic acut respiratori dysfunct reveal potenti effici high flow oxygen therapi acut pancreat complic acut respiratori dysfunct compar convent oxygen therapi
|
D010195;D012131;D063087
|
T061;T047;T046
|
36,326,306
|
oncometabolit urin new opportun detect prognosi clinic progress verifi prostat cancer pilot studi oncometabolit provid new approach toward diagnost prognosi clinic progress prostat cancer pca studi diagnost predict valu panel urinari oncometabolit ethanolamin kynurenin alanin alanin leucin isoleucin aminobutyr acid sarcosin correl prostat specif antigen psa gleason score patient diagnos prostat cancer
|
D017430;D011471
|
T129;T191;T126;T116
|
36,326,305
|
diagnost valu hsp monitor treatment respons lung cancer heat shock protein hsp consid tumor biomark mani human malign studi investig diagnost valu hsp combin tradit lung cancer biomark cea cyfra nse role monitor treatment respons lung cancer patient
|
D000230;D008175
|
T191
|
36,326,304
|
evalu organ load relat efficaci chang antisept solut use hospit studi aim evalu chang antimicrobi efficaci relat presenc organ load four differ antisept solut frequent use hospit
|
D011206;D000891
|
T121;T109
|
36,326,303
|
pertussi preval among adult patient acut cough bordetella pertussi infect remain import health problem adult due increas preval recent year pertussi adult easili overlook misdiagnos aim determin preval pertussi adult patient acut cough clinic featur pertussi case
|
D014917
|
T047
|
36,326,245
|
mechanobiolog cell wall insight tip grow plant fungal cell cell wall cw thin rigid layer encas membran plant fungal cell ensur mechan integr bear mechan stress deriv larg cytoplasm turgor pressur contact grow neighbor growth within restrict space cw made polysaccharid protein dynam natur chang composit geometri growth reproduct infect continu often rapid remodel entail risk enhanc stress consequ damag fractur rais question cw detect measur surfac mechan stress strengthen ensur surfac integr although earli studi model fungal plant cell identifi homeostat pathway requir cw integr recent methodolog allow measur pressur local mechan properti cws live cell well address forc stress detect cw surfac foster emerg field cw mechanobiolog use tip grow cell plant fungi case studi model review recent progress cw mechanosens mechan regul implic control cell growth morphogenesi surviv
|
D002473;D059828
|
T026;T025
|
36,326,235
|
associ anaemia co morbid red blood cell transfus accord age group multicentr sub analysi german patient blood manag network registri blood transfus common medic procedur everi age group requir detail insight treatment bundl aim studi examin associ anaemia co morbid complic hospit mortal transfus accord age group identifi patient group particular risk undergo surgeri
|
D017707;D000740
|
T061;T047
|
36,326,227
|
covid treat diseas fall sinc arriv covid wit seri new variant new therapi therefor becom difficult stay date best manag outpati infect sar cov patient risk unfavor evolut first day ill antivir paxlovid recommend evusheld administ hospit recommend patient document negat serolog treatment earli diseas pre exposur prophylaxi activ monoclon antibodi seem reduc new variant dexamethason reserv hospit manag oxygen depend patient place antibiot therapi apart addit bacteri infect
|
D000086382;D065129
|
T061;T047;T067
|
36,326,226
|
fast evolv cognit impair home base diagnosi syphili sexual transmit diseas incid increas last year switzerland clinic neurocognit manifest observ case symptomat neurosyphili heterogen mimic neurocognit disord origin articl discuss diagnost manag pitfal older patient whose diagnosi neurosyphili initi suspect home visit
|
D009494;D060825;D012749;D013587
|
T047;T048
|
36,326,225
|
ortho geriatr rehabilit challeng impact risk develop function depend rise age follow acut event rehabilit stay often need restor function capac consid home discharg geriatr rehabilit process usual involv standard multidisciplinari manag set frequent review goal discharg plan retrospect observ studi conduct orthogeriatr rehabilit conduct geneva comorbid function status admiss length stay appear signific impact recoveri potenti destin discharg wherea intens rehabilit program number therapi per week influenc patient outcom
|
D010351;D006760
|
T058
|
36,326,224
|
infecti diseas ward dedic elder patient manag infect elder requir medic nurs expertis standard global geriatr evalu present origin pioneer unit switzerland dedic polymorbid complex elder patient hospit acut infect benefit joint manag interdisciplinari team includ geriatrician infecti diseas specialist pharmacogeriatrician hpital des troi chne geriatr emerg intermedi care bed somadem somat dementia ugimp medico psychiatr program adapt popul seem ideal place host unit team benefit theoret practic train associ field coach
|
D005853;D003141
|
T090;T047;T091
|
36,326,223
|
treatment congest heart failur older person sglt inhibitor patient best interest heart treatment manag heart failur hf constant evolv latest guidelin recommend use sglt inhibitor sglti integr part treat hf reduc eject fraction howev given patient includ trial reflect heterogen health mani elder patient recommend base therapeut decis patient state frailti sglti treatment standard dose mg xday recommend robust patient suggest initi treatment mg xday vulner patient month increas dose mg xday final depend patient recommend therapeut abstent absenc suffici scientif evid
|
D000077203;D003924;D006333
|
T121;T047;T046;T109
|
36,326,222
|
subacut cerebellar ataxia uncommon sar cov complic infect older adult cerebellar ataxia caus neoplasia toxic drug heavi metal alcohol infect vascular lesion auto immun paraneoplast patholog neuroimag must perform urgent case sudden onset serolog well lumbar punctur perform sever case report ataxia associ covid publish howev under pathogen mechan remain unclear diagnosi exclus caus rule ataxia appear simultan covid infect lack data best manag prognosi appear most favor good function recoveri without specif treatment paper describ case patient develop cerebellar ataxia neurolog manifest sar cov infect
|
D002524;D000086382
|
T033;T184;T047;T067
|
36,326,221
|
geriatr syndrom polypharmaci prescrib proscrib question appli treatment recommend various knowledg specialist societi concern complex patient within popul weaken cumul effect comorbid loss autonomi aggrav geriatr syndrom biolog chang link age interact pharmacokinet pharmacodynam drug fertil soil advent advers condit link simultan prescrib multipl treatment aim analyz various clinic reason tool permit appropri drug prescript consid state health life expect time benefit aim reduc iatrogenesi
|
D019338;D011307
|
T061;T058;T170
|
36,326,118
|
intervent perceptu disord follow stroke percept abil understand inform sens allow us experi meaning interact environ stroke may impair percept stroke survivor lead distress increas depend other poorer qualiti life intervent address perceptu disord may includ assess screen rehabilit non invas brain stimul pharmacolog surgic approach
|
D010468;D020521;D000071939
|
T061;T047;T048
|
36,326,097
|
neural stem cell research africa current realiti futur prospect neural stem cell nscs immatur progenitor cell found develop adult brain potenti divid activ renew complex form gene express generat new brain cell adult individu initi consid imposs howev landmark discoveri human neural stem cell hippocampus follow discoveri discreet region brain investig current state africa research use nscs show relat limit activ contin inform african applic nscs model diseas mechan drug discoveri therapeut still limit intern brain research organ ibro african region committe arc support compani biologist movement disord societi sponsor first african basic school nsc ibadan nigeria vision bring togeth young neuroscientist physician across differ field neurosci learn leader appli nscs stem cell research pathophysiolog neurodegen diseas neuroanatomi neurotherapeut twenti earli career research academ institut junior senior faculti cadr select south africa uganda nigeria student organ school wrote review state nscs research africa recommend follow african countri take cue south africa nigeria probe phenomena adult neurogenesi uniqu anim speci contin africa leverag expertis facil south african scientist intern collabor scale nsc research uniqu speci center excel establish contin serv research hub train postgradu student facil african scientist train oversea nscs
|
D057905;D058953
|
T062;T025
|
36,326,002
|
screen vitro silico effect fluorophenylthiourea compound glucos phosphat dehydrogenas phosphoglucon dehydrogenas enzym inhibit studi enzym pentos phosphat pathway ppp recent emerg promis techniqu pharmacolog intervent sever ill glucos phosphat dehydrogenas gpd phosphoglucon dehydrogenas pgd import enzym ppp purpos current studi examin effect fluorophenylthiourea gpd pgd enzym activ compound exhibit moder inhibitori activ gpd pgd k valu rang respect difluorophenylthiourea display potent inhibitori effect gpd fluorophenylthiourea demonstr substanti inhibitori effect pgd furthermor molecular dock analys fluorophenylthiourea competit inhibitor perform understand bind interact enzym bind site
|
D010734;D005947
|
T123;T121;T116;T109;T126
|
36,326,001
|
molecular design ration optim synergist effect two wing rough orthogon cation stack system nasopharyng carcinoma yap tead parallel helix helix interact interfac yes associ protein yap essenti regul human hippo signal pathway function interact tea domain tead transcript factor involv tumorigenesi nasopharyng cancer previous parallel helix helix interact phhi identifi key hotspot yap tead complex interfac exploit attract druggabl target disrupt complex studi investig rough orthogon cation stack system across crystal phhi pack interfac integr comput model bind assay form one yap helic residu phe two tead helic residu pheli synergist effect cation interact observ separ repres two wing stack system electron primarili respons synergist effect combin divers aromaticcharg amino acid well neutral alanin cation stack reveal presenc aromat tryptophan charg arginin respect residu tead helix consider improv phhi bind affin fold wherea neutral alanin substitut residu would reduc affin signific confirm strong synergist effect involv rough orthogon cation stack system yap tead phhi interfac
|
D000091262;D009303
|
T123;T191;T116
|
36,326,000
|
pharmacogenom medic given via nonconvent administr rout scope review pharmacogenom pgx implement becom increas widespread one import aspect implement process develop appropri clinic decis support cds major pgx resourc clinic pharmacogenet implement consortium provid valuabl recommend develop cds specif gene drug pair specifi whether administr rout drug clinic relev also unknown pgx alert nonor non intraven administ pgx relev medic suppress reduc alert fatigu purpos scope review identifi studi clinic pharmacokinet pharmacodynam outcom better determin cds alert relev nonor non intraven administ pgx relev medic although scope review identifi multipl pgx studi result studi inconsist evid need regard differ rout medic administr pgx
|
D010597;D020000
|
T058;T170;T091
|
36,325,955
|
energi drink consumpt pattern advers effect adolesc health energi drink general contain caffein stimul commerci aim young peopl previous research suggest effect adolesc health danger aim studi evalu effect taurin caffein consumpt energi drink adolesc health identifi pattern consumpt associ physiolog symptom
|
D061215;D064420
|
T168;T046;T037
|
36,325,877
|
patient organ ehealth servic model current finnish public hospit ehealth servic organ orient rather patient orient patient remain passiv use ehealth servic design privat government organ patient littl involv process paper introduc novel ehealth servic model use tool captur need organ patient two ehealth servic use verifi support valid present model first ehealth servic featur came exist finnish ehealth servic design finnish organ second ehealth servic featur deriv collect patient feedback survey carri compar select two ehealth servic featur find paper suggest ehealth servic featur captur patient need favor ehealth servic featur came finnish organ present model long term solut util design provid right technolog servic continu satisfi need patient organ
|
D017216
|
T058
|
36,325,876
|
human resourc plan health care outlin basic model relat complex effect health care system larg depend knowledg skill motiv health care worker particular evid covid pandem system plan human resourc therefor import condit ensur sustain effici health care system articl focus outlin basic model human resourc plan health care investig relat complex depth analysi framework base various materi evid propos order outlin factor influenc human resourc plan health care order achiev greater credibl research result depth analyt process employ extens review literatur carri investig numer sourc materi nation intern context purpos human resourc plan initi health care calcul need number health care worker futur basi past current data base assumpt futur trend suppli demand research find reveal challeng task typic mani unknown futur plan addit planner often face lack reliabl data system defici moreov studi indic unplan delay solut concern human resourc need health care allevi problem way replac effect strateg measur time structur chang within health care ecosystem
|
D058873;D000086382
|
T047;T067
|
36,325,875
|
migrat hl cda fhir infecti diseas system estonia basi estonian nation health system propos univers reusabl methodolog migrat hl cda document compon
|
D057208;D003141
|
T047;T093
|
36,325,874
|
identif medicin product provid educ framework iso standard identif medicin product idmp prove difficult implement guidanc need provid use develop idmp relat standard terminolog provid fit structur educ would step forward articl describ research current educ certif idmp creation educ framework target idmp knowledg transfer framework indic requir level knowledg various identifi role within organ work idmp base combin desk research questionnair individu interview relev role identifi cover various organ user educ medicin author standard develop organ supplier five level requir knowledg determin includ applic role educ compon furthermor articl list sever recommend taken consider whilst develop content implement educ modul idmp
|
D002568;D009938
|
T081;T092;T064
|
36,325,873
|
chang manag hospit framework analysi hospit complex organ frequent need chang especi servic deliveri process organ human resourc manag monitor evalu technolog maintain improv product key requir hospit chang manag therefor need develop expand appropri model manag chang hospit main purpos studi
|
D000078003;D006739
|
T058;T057
|
36,325,872
|
bibliometr analysi trend research wearabl technolog cardiovascular diseas paper bibliometr analysi research wearabl technolog cardiovascular diseas conduct bibliometrix base paper collect scopus interest result present us china stood sustain product field cardiovascular diseas examin author keyword reveal respir person applic popular research topic howev attent given ecg wearabl devic wearabl sensor heart rate studi suggest present decad research focus topic relat artifici intellig hypertens ecg wearabl sensor african countri must address technolog gap come year
|
D002318;D000076251
|
T047;T073
|
36,325,871
|
usabl iranian primari vitiligo patient registri ipvpr pilot studi usabl essenti accept success vitiligo patient registri system poor usabl could decreas system effici effect negat impact use system provid servic studi aim evalu usabl vitiligo patient registri system
|
D014820
|
T047
|
36,325,870
|
learn qualiti requir isot evalu convers agent healthcar evalu convers agent ca suppos appli healthcar ensur qualiti essenti avoid patient harm howev research studi usabl use ca clinic trial conduct care evalu previous work consensus metric evalu healthcar ca found howev metric still generic form evalu framework work tri link iso technic specif isot qualiti requir health well app set metric come step closer toward evalu framework identifi three link iso requir set metric name access usabl secur although technic specif rather list aspect consid develop instead concret metric studi qualiti link aspect also interest health ca evalu exampl measur readabl ensur access implement web content access guidelin two aspect relev health ca
|
D003695;D006268
|
T058;T073;T093
|
36,325,869
|
forecast trend tuberculosi epidem situat region russian feder dynam simul model spread new coronavirus infect last two year togeth hiv infect preserv even increas potenti spread tuberculosi world sverdlovsk oblast russian feder region high level hiv tuberculosi tb search new method forecast futur epidem situat tuberculosi becom particular relev aim develop effect method predict epidem situat tuberculosi use artifici intellig ai method format dynam simul model base ai technolog statist data load state statist report tb patient period paramet control system inequ propos sdm made possibl identifi reliabl calcul trend tb epidemiolog indic comparison predict valu made actual valu reveal reliabl coincid trend movement tb epidemiolog indic region maximum deviat forecast result obtain sdm quit suitabl practic use especi oper resourc plan measur counteract spread tuberculosi region level
|
D015658;D014376;D058872
|
T047;T067
|
36,325,868
|
structur research direct medic domain topic model applic phd these synops dentistri studi analyz scientif text base manual creat databas synops these dentistri main goal structur medic text various topic mean natur languag process techniqu topic model furthermor dynam topic model show popular field dentistri almost last thirti year
|
D009323;D003813
|
T091;T066
|
36,325,867
|
visual benchmark simul clinic data avail big data increas signific mani area recent year insight data set lead optim process mani industri understand well gain knowledg analys data set becom increas relev medic field especi intens care unit fast appropri treatment crucial due usual critic condit patient patient data record often heterogen result databas model complex access thus use data requir technic background knowledg focus develop web applic primarili aim clinic staff research easili access visual benchmark tool provid graphic interfac mimic iii databas anonym dataset contain mimic iii includ general inform patient well characterist vital sign laboratori measur dataset great interest use improv digit decis support system clinic process therefor addit visual applic use research valid anomali detect algorithm clinic staff assess diseas progress purpos patient data individu modif increas decreas vital sign laboratori paramet diseas progress simul subsequ analyz accord user specif need
|
D019985;D012984
|
T081;T090;T170;T073
|
36,325,866
|
analysi represent frequent clinic attribut unifi medic languag system map clinic attribut hospit inform system standard terminolog may allow scientif reus multicent studi unifi medic languag system uml defin synonym differ terminolog could valuabl achiev semant interoper differ site aim explor potenti relev uml concept associ semant relat wide use clinic terminolog german univers hospit semi automat examin sampl frequent code erlangen univers hospit three relev terminolog implement script queri uml represent associ map via program interfac found frequent diagnost code avail uml code could map terminolog snome ct observ examin laboratori code repres uml various translat languag avail concept classif wide use german hospit document clinic procedur origin repres uml extern map snome ct allow identifi uml entri frequent code futur research could extend investig code set terminolog studi potenti util avail map specif applic
|
D017432;D039061
|
T170
|
36,325,865
|
inform system integr genet inform clinic knowledg paper deal develop inform system call person genet card pgc system aim integr known clinic knowledg interpret recommend link genet inform analysi result patient genet inform increas influenc clinic decis physician well medic health servic servic need connect genet profil phenotyp drug metabol drug toxic drug dose intoler substanc still appli best way repres data medic record structur form record mani approach use defin structur syntax record content semant record exchang data form various standard terminolog moreov genet analysi field terminolog databas repres genet inform eg hgnc ncbi next step connect genet analysi result c clinic knowledg interpret recommend step crucial genet analysi result clinic benefit assign valid clinic knowledg best final result make better recommend base genet result clinic knowledg genet knowledg databas eg pharmgkb snpedia clinvar contain mani interpret even recommend genet analysi result base differ purpos situat appropri develop pgc system take inspir case base reason purpos allow integr assumpt knowledg phenotyp real genet analysi result structur form
|
D016347;D005820
|
T060;T170;T059;T073
|
36,325,864
|
abai novel autom ai tool report antibiogram anti microbi resist one greatest threat mankind face right due inappropri use antibiot institut appropri antibiot right dose right patient right time gamechang fight amr antibiot sensit test ast antibiogram done ascertain sensit profil organ wide use method laboratori practic india kirbi bauer disk diffus test shortcom manual interpret antibiogram form high inter oper variabl mandatori requir train microbiologist difficult low resourc set high degre interperson bias due various factor like stress workload visual acuiti propos abai tool autom ast procedur laboratori abai tool compris phase first data collect second data process third generat antibiot sensit report various softwar packag like opencv easyocr use develop abai tool total antibiogram gpc gnb interpret manual autom method manual method consid gold standard perform abai tool compar manual method abai tool achiev agreement suscept categor gpc antibiot gnb antibiot gold standard manual method propos abai tool serv perfect candid autom ast procedur would prove game changer battl amr
|
D024881;D000900
|
T121;T032;T195
|
36,325,863
|
develop implement data scienc learn platform research physician data analysi applic unavoid factor activ analys health care unfortun acquisit data larg avail medic databas complex process requir deep knowledg comput scienc especi knowledg tool data manag accord european general data protect regul problem becom much complex recogn problem difficulti develop data scienc learn platform dslp primarili target practition research also comput scienc student use propos tool chain togeth develop graphic user interfac data scientist research physician abl use avail medic databas appli analyz differ anonym method analyz data accord patient risk quick formul new studi target diseas complex data model articl present clinic research discoveri toolbox implement demonstr tool data anonym patient data visual nlp tool guidelin search data scienc learn tool
|
D000077488;D010820
|
T090;T097
|
36,325,862
|
nonalcohol steatohepat diagnosi model relat person medicin approach nonalcohol fatti liver diseas nafld clinic syndrom patholog character diffus macro vesicular fatti chang hepatocyt nafld includ simpl nonalcohol fatti liver diseas nonalcohol steatohepat nash hepat cirrhosi nash diseas evolv influenc various stimuli still poor understood insulin resist promin paper present new diagnosi model predict nash
|
D065626
|
T047
|
36,325,861
|
person trait secur motiv secur awar train long consid critic element organiz cybersecur prepared mandatori activ mani law regul well cybersecur manag standard iso organ approach issu differ method mani reli onlin train cost effect way reach larg number employe low cost train deliv voluntari measur essenti knowledg factor contribut motiv particip studi use theoret concept protect motiv theori pmt well look individu person trait might affect willing particip survey conduct larg norwegian municip data analyz pls sem studi found support concept cost effect affect motiv vulner sever person trait extrovers agreeabl found moder effect
|
D009042;D010551
|
T078;T041;T080
|
36,325,860
|
characterist subject evalu intellig empow agent health person empower empower process peopl acquir necessari knowledg self awar understand health condit treatment option self manag make inform choic current stand alon applic patient empower exist peoplepati often go web search health inform inform main obtain generic search engin often overwhelm generic poor qualiti intellig empow agent iea filter inform assist user understand health inform specif complaint health general design develop first prototyp iea dialogu user simpl languag collect health inform web provid tailor easili understood trust inform empow user creat comprehens object opinion health matter concern paper describ iea main characterist present result subject test carri assess effect iea twenti eight master student digit health fill onlin survey present question usabl user experi perceiv valu respond found iea easi use help also felt would improv communic doctor
|
D000079102;D010358
|
T081;T058;T054;T080
|
36,325,859
|
proven dynam consent manag medic data medic data describ patient health inform healthi diseas condit case health institut need ask patient consent order provid servic patient usual give consent one time basi specif usag afterward medic data usag research origin patient consent appli consent requir hand proven medic data verifi origin health procedur desir digit health increas propos hipam modular architectur provid proven dynam consent medic data describ paper
|
D007258
|
T089
|
36,325,858
|
inform secur risk welfar technolog person healthcar devic welfar technolog expect becom larger import part healthcar sector creat need understand inform secur risk welfar technolog affili devic expos scope review present extens overview relev threat furthermor key vulner health technolog like iomt welfar technolog devic highlight conclus risk relev welfar technolog discuss four top risk emphas result find
|
D016494;D003695
|
T078;T080;T093;T170;T097;T058;T057
|
36,325,857
|
decentr ehr semant web better health data manag electron health record ehr system current use design wide interoper longitudin health data therefor ehr data proper share manag analyz articl propos two approach make ehr data comprehens fair findabl access interoper reusabl thus use diagnosi clinic research first data model base linkml framework make data interoper realist divers environ various expert involv show first result divers health data integr base easi understand data model without loss avail clinic knowledg second decentr ehr contribut higher avail comprehens consist ehr data propos technolog stack decentr ehr reason behind propos moreov two propos approach empow patient ehr data becom avail understand usabl share data accord need prefer final explor user propos solut could involv process valid adopt
|
D000075403;D057286
|
T170;T073
|
36,325,856
|
etl process integr healthcar data tool architectur pattern improv interoper healthcar inform system crucial clinic care issu involv dispar coexist inform system howev healthcar organ also face dilemma choos right etl tool architectur pattern data warehous enterpris articl give overview current etl tool healthcar data integr addit demonstr three etl process clinic data integr use differ etl tool architectur pattern map data various data sourc eg meona orbi divers standard eg fhir openehr depend project technic requir choos etl tool softwar architectur pattern boost team effici
|
D057286;D000073458
|
T170;T073
|
36,325,855
|
electron health record peopl hand across europ interopehr protocol share person health data could facilit enhanc qualiti care conduct research studi howev data still underutil due legal technic interoper challeng wherea data subject abl manag interact decid share purpos barrier obstacl continu care across european union eu neither healthcar provid data research citizen benefit effici healthcar treatment research despit sever nation level eu studi research activ cross border health data exchang share still challeng task address specif case scenario manuscript present interopehr research project along key innov aim offer electron health record ehr peopl hand across eu via exploit three differ protocol famili name devic devic dd remot devic rd research data share rds protocol protocol facilit effici secur privaci preserv general data protect regul gdpr compliant health data share across eu cover differ real world use case
|
D057286;D018907
|
T033;T089;T170;T073
|
36,325,854
|
fhir base contsi ontolog enabl continu care data interoper midst global pandem perspect digit enhanc healthcar servic deliveri workflow address global crisi underway action plan collat exist digit transform program scrutin set place core infrastructur foundat sustain healthcar solut reform health social care person home care set exampl assist avoid treatment crow acut hospit set improv experi impact health care profession servic user alik inform intens domain address interoper challeng standard base roadmap lynchpin enabl health social care servic connect effect thus facilit safe trustworthi data workflow one healthcar system provid anoth paper showcas methodolog extract transform load data semi autom process use common semant standard data model cssdm generat person healthcar knowledg graph kg cssdm base formal ontolog iso contsi conceptu ground fhir base specif accommod structur attribut generat kg cssdm suggest enabl data harmon data link goal cssdm offer altern pathway speak interoper support differ kind collabor compani creat health inform system cloud enabl health servic pathway communic provid access multipl stakehold share high qualiti data inform
|
D057286;D006699
|
T058;T170;T073
|
36,325,853
|
overview secur privaci data iomt devic perform metric merit demerit challeng internet medic thing iomt emerg new trendsett devic applic defin incorpor medic devic internet thing iot healthcar sector continu encount challeng obstacl impact qualiti treatment provid patient get rid problem iomt deploy achiev high reliabl effici health system iomt devic superimpos clinic inform contain detail patient health data address patient identifi contain amount sensit inform becom cumbersom preserv data privaci secur due inadequ secur privaci precaut patient health data suscept leakag direct impact patient life addit major medic devic suscept cyberattack put patient inform risk inadequ control life support equip devast effect patient outcom thus survey intend review various secur model iomt devic use standard techniqu support health care system provid wide rang literatur review regard iomt system compar tradit methodolog review work exhibit motiv current technolog maintain secur privaci patient data iomt devic systemat review entail background secur iomt devic techniqu secur usag divers valid measur also discuss problem motiv futur research work
|
D000080487
|
T170
|
36,325,852
|
manag cancer patient covid crisi use telemedicin systemat review telemedicin provid solut diseas manag covid pandem literatur review aim explor role telemedicin covid pandem manag cancer patient
|
D000086382;D017216;D009369
|
T047;T191;T058;T067
|
36,325,851
|
privaci trust phealth past present futur begin today phealth data driven servic collect use person health inform phi person health servic person healthcar result phealth servic use intens ict technolog sensor comput mathemat algorithm past phealth applic focus certain health sick relat problem today use mobil devic wireless network web technolog cloud platform futur phealth use inform system high distribut dynam increas autonom multi stakehold data driven eco system abil monitor anywher person regular life movement health relat behaviour privaci trust pre requir success phealth develop rais huge privaci trust challeng solv research shown current privaci approach solut use phealth offer accept level privaci trust illus indic today privaci model technolog shall move futur phealth author analys interest new privaci trust idea publish journal found seem effect offer partial solut solv weak author use holist system view aspect impact privaci trust phealth creat templat use plan develop futur phealth servic author also propos tentat solut futur trustworthi phealth combin privaci person properti trust legal bind fiduci duti approach use blockchain base smart contract solut store person privaci trust requir servic provid promis
|
D018907;D055991
|
T033;T089;T170;T073
|
36,325,850
|
assess human mobil construct skelet databas augment use generat adversari network gan simul paper present neural network simul base anonym patient motion measur categor infer human gestur base librari anonym patient motion need suffici train set deep learn applic dl propos extend databas includ limit number video human physiotherapi activ synthet data result postur generat abl generat skelet vector depict human movement human skelet model generat use openpos op multipl person video photograph everi video frame op repres human skelet posit vector euclidean space gan use generat new sampl control paramet motion joint skelet model restructur emphas linkag use depth first search dfs method search tree structur addit work explor solut common problem associ acquisit human gestur data synchron activ link time space new simul propos generat sequenc virtual coordin human movement base upon script
|
D016571;D009068
|
T040;T170
|
36,325,849
|
studi user behaviour caus automat recommend system call action diagnost accuraci usabl symptom checker research sever studi abil set correct diagnosi especi urgent case question one aspect symptom checker deepli studi yet abil motiv patient follow receiv direct recommend decreas load health care profession goal research studi patient behav receiv recommend symptom checker motiv behavior studi patient react symptom checker recommend motiv behind behavior total invit patient symptom checker screen agre run symptom checker screen agre particip studi proport patient agre symptom checker screen clear see symptom checker screen nt result signific decreas load healthcar profession support quantit studi result patient emphas eas use tool clear recommend give howev perceiv rather second opinion tool tool help prepar doctor visit
|
D012017;D006282
|
T058;T170;T097
|
36,325,848
|
causal plausibl decis healthcar explos interest exploit machin learn techniqu healthcar brought issu infer causat observ data centr stage work support health decis individu personpati person point care avoid make decis option includ exclud decis support tool research routin injunct use find caution methodolog limit lead inclus exclus task one decid first causal plausibl causal like decis sensit error prefer trade off engag select artifici intellig ai literatur causal challeng close associ issu explain demand black box ai commit embrac lifestyl well medic option individu person lead us highlight key issu make prefer sensit decis causal plausibl causal
|
D001185;D003695
|
T090;T073;T093;T066;T058
|
36,325,847
|
risk factor covid systemat map studi covid affect peopl sever countri around world experi respiratori symptom mild moder sever sever review character risk factor covid perform address risk factor associ medic condit ignor environment sociodemograph socioeconom factor
|
D000086382
|
T047;T067
|
36,325,846
|
respons center servic exploratori studi popul age facilit grow number welfar technolog smart home solut technolog enabl clinic staff health care profession provid health servic intellig way trend patient centric digit health platform one health servic respons center servic face new challeng connect welfar technolog fals alarm secur threat privaci leakag etc paper introduc mechan respons center role play healthcar conduct exploratori studi find benefit challeng respons center servic result structur interview base find identifi requir servic improv intellig respons center mechan
|
D003695;D006699
|
T058;T093
|
36,325,845
|
cts owl map owl ontolog cts terminolog resourc advanc healthcar toward p medicin requir communic cooper actor institut involv interoper must go beyond integr data differ sourc includ understand mean data context concept context repres specif use case word advanc data share share semant share clinic medic knowledg accord good model best practic start describ real world busi system domain expert use domain ontolog transform inform communic technolog ict system thereaft specifi inform compon transform system implement solut represent style system develop process acc iso call system view defin relat ontolog distinguish real world domain ontolog repres knowledg space involv disciplin system enabl represent transform shall also support version well manag histor evolut one system common terminolog servic releas cts standard allow complet manag terminolog content main object work present choic made transform ontolog written standard ontolog web languag owl cts object test transform approach alzheim diseas ontolog manag map element consid ontolog cts terminolog resourc except subset element equivalentclass deriv restrict class
|
D007802;D064229
|
T171;T170
|
36,325,844
|
obstacl ehealth capac build innov promot initi african countri ehealth applic tool potenti improv coordin knowledg inform share health profession well continu care one main obstacl hinder full integr use particular healthcar sector develop low middl incom countri lack qualifi staff healthcar personnel explor obstacl hinder capac innov promot initi survey conduct among betterehealth partner questionnair use collect quantit data organ although differ bucket capac build innov promot activ go find show target policymak ehealth specialist find found obstacl capac build innov promot includ lack financ poor infrastructur poor leadership govern obstacl context region specif find studi concur previous research need identifi practic solut simpl intervent address ehealth obstacl capac build develop countri measur mitig obstacl studi propos need adequ polici strong polit commit develop academ modul integr exist educ program creation countri site capac build activ studi contribut discours ehealth capac build innov promot initi among healthcar public health profession studi limit data collect betterehealth partner
|
D057191;D017216
|
T058
|
36,325,843
|
socio technic regim transit model gerontechnolog servic design privaci inform secur cyber secur focus paper present ongo research use socio technic privaci inform secur cybersecur model support design develop deliveri process health care servic age place current research gerontechnolog servic develop review experi use serious game evalu model outlin
|
D018907;D057187
|
T033;T089;T056
|
36,325,842
|
standard principl enabl interoper integr p medicin ecosystem health social care ecosystem current matter foundat organiz methodolog technolog paradigm chang toward person prevent predict particip precis p medicin design implement advanc ecosystem understand correct represent structur function relat compon inevit guarante consist conform process outcom specif principl must intern standard summar first author keynot last year phealth confer paper discuss concept standard principl p medicin ecosystem includ design implement furthermor guidanc find deploy correspond intern standard practic project provid
|
D017753;D057285
|
T061;T070;T091;T082
|
36,325,796
|
fish infect trypanosoma micropteri belong trypanosoma carassii recent base limit morpholog characteris partial rrna gene sequenc jiang et al describ trypanosoma micropteri jiang lu du wang hu su et li new pathogen farm fish provid evid base expand sequenc dataset morpholog experiment infect trypanosom warrant establish new speci conspecif long term known trypanosoma carassii mitrophanow common haemoflagel parasit freshwat fish former taxon thus becom new junior synonym carassii
|
D014345;D014352
|
T047;T204
|
36,325,794
|
retrograd transurethr contrast enhanc ultrasound diagnosi bladder ruptur report two case bladder ruptur refer seri diseas caus bladder wall lacer urin flow abdomin cavitytwo case bladder ruptur diagnos retrograd transurethr contrast enhanc ultrasound review reportw discuss valu retrograd transurethr contrast enhanc ultrasound diagnosi classif prognosi evalu bladder ruptur aim provid evid clinic diagnosi treatment
|
D001743
|
T023
|
36,325,793
|
psittacosi pneumonia pleural effus report three case literatur review general believ psittacosi pneumonia pneumonia caus chlamydia psittaci rare combin pleural effus characterist pleural effus rare report domest literatureherein report three case pleural effus due psittacosi pneumonia elev level adenosin deaminas lymphocyt predomin exud pleural effusionfurth review psittacosi pneumonia report complet clinic lung imag datath imag manifest includ pulmonari consolid common occurr small amount pleural effusionth patient psittacosi pneumonia combin pleural effus sever symptom obvious hypoxia increas risk invas ventil
|
D009956;D002691;D010996;D011014
|
T047;T007;T050
|
36,325,792
|
research progress circadian rhythm arrhythmia studi demonstr occurr varieti arrhythmia present obvious circadian rhythm may regul circadian rhythm genescircadian cycl light stimul affect circadian rhythm gene protein constitut transcript translat loop regul ion channel myocardi cell membran nervous humor regul chang central clock sub clock gene express therebi modul arrhythmiathi articl review molecular basi mechan perform circadian rhythm regul arrhythmia
|
D002940;D032383
|
T040;T025
|
36,325,791
|
research progress mechan lipid nephrotox dyslipidemia damag varieti organ includ kidneyth mechan lipid induc kidney injuri includ autophagi defect oxid stress endoplasm reticulum stress inflamm epigenet modificationthi articl review recent research progress field
|
D018384;D001343
|
T049;T043
|
36,325,790
|
research progressin singl nucleotid polymorph vitiligo suscept gene vitiligo depigment diseas affect varieti offactor genet factor play key rolesingl nucleotid polymorph common type genet variat detect candid gene analysi genom wide associ studyth recent studi demonstr multipl suscept gene play vital role occurr develop vitiligothi articl introduc singl nucleotid polymorph vitiligo suscept gene accord gene function
|
D020641;D014820
|
T047;T086
|
36,325,789
|
advanc treatment human epiderm growth factor receptor positv gastric cancer gastric cancer rank fifth common malign tumor worldwid fourth lead caus cancer relat deathshuman epiderm growth factor receptor posit gastric cancer special type gastric adenocarcinoma prognosi improv trastuzumab plus cytotox chemotherapi cisplatin fluorouracilpembrolizumab basi tmabplus chemotherapi improv overal respons rate becom first line standard therapi posit gastric cancerhowev still obstacl innat resist tmab specif populationsth research target therapi provid clue clinic decis makingthi review document current neoadjuv adjuv therapi late stage posit gastric cancer well progress novel pathway target drug
|
D013274
|
T191
|
36,325,788
|
advanc diaphragm ultrasound anesthesia manag diaphragm excurs diaphragm thick diaphragmat thicken fraction three indic evalu two hemidiaphragm ultrasounddiaphragm ultrasound wide appli clinic practic includ anesthesia managementit help diagnos postop residu curaris identifi patient high risk suffer postop pulmonari complicationsit serv recogn patient diaphragm paralysi due surgic anesthet factor earli possiblemoreov diaphragm ultrasound play role preoper pulmonari function assess special suffer chronic obstruct pulmonari diseas adolesc idiopath scoliosi neuromuscular diseaseapart diaphragm ultrasound give anesthesiologist colleagu intens care unit import clue extub wean mechan ventil patient
|
D003964;D000758
|
T061;T023
|
36,325,787
|
advanc mechan blood brain barrier impair induc sleep depriv sleep depriv process state partial complet lack normal sleep caus various factor preval presentseri impair physic mental health sleep depriv becom public health problem ignoredstudi demonstr blood brain barrier impair key pathophysiolog process varieti neurolog diseasesalthough clinic basic studi suggest sleep depriv induc blood brain barrier impair under mechan remain elucidatedthi review summar advanc mechan blood brain barrier impair induc sleep depriv
|
D012892;D001812
|
T033;T047;T046;T023
|
36,325,786
|
research progress clinic electrophysiolog assess patient sepsi associ encephalopathi sepsi associ encephalopathi sae caus infect outsid central nervous system alway present extens brain damageit common clinic practic associ poor prognosisther problem assess diagnos saemani factor sedat mechan ventil make difficult assess sae electrophysiolog examin may play role assessmentw review studi electrophysiolog techniqu electroencephalographi somatosensori evok potenti monitor sae hope provid certain evid clinic evalu diagnosi sae
|
D065166;D018805
|
T047;T046;T048
|
36,325,785
|
research progress ubiquitin proteasom inhibitor acut myeloid leukemia ubiquitin proteasom system up play essenti role eukaryot protein cycl dysregul lead tumorigenesisincreas activ up observ patient cancer includ leukemiaup inhibitor kill cancer cell affect ubiquitin ligat enzym e deubiquitinas protein degrad activ site upstherefor up inhibitor emerg import therapi treat hematolog malign rare appli treatment acut myeloid leukemiathi paper summar research progress inhibitor affect protein ubiquitin differ stage acut myeloid leukemia aim provid new clue clinic treatment acut myeloid leukemia
|
D061988;D015470
|
T121;T191
|
36,325,784
|
research progress pleckstrin homolog like domain famili member tumor pleckstrin homolog like domain famili member phlda also known cell death associ gene tdag studi demonstr abnorm express phlda close associ format develop metastasi tumorsw summar latest research advanc structur biolog properti phlda well role phlda multipl malignanttumor breast cancer cancer liver gastric cancer liver cancer melanoma osteosarcoma aim comprehens reveal signific phlda clinic diagnosi tumor
|
D014157;D001943
|
T123;T191;T116
|
36,325,783
|
poor oral health sarcopenia elder review correl intervent measur sarcopenia common geriatr syndrom associ occurr advers consequ fall debil death serious affectingth qualiti life elderlyor health basi overal health play vital role improv overal qualiti life extend healthi life span elderlystudi demonstr poor oral health may increas risk sarcopeniabi review recent studi oral health sarcopenia elder summar relat mechan put forward intervent measur provid theoret basi prevent treatment sarcopenia aspect oral health
|
D055948
|
T047
|
36,325,782
|
mechan mesenchym stem cell treatment asthma asthma chronic inflammatori diseas respiratori system character airway hyperrespons chronic airway inflamm mucus secret airway remodelingmesenchym stem cell msc kind multifunct stem cell abil self renew multi direct differentiationthey involv varieti physiolog process immun respons antigen present inflammatori respons cell migrationmsc play key role pathogenesi bronchial asthma under mechan remain studiedmsc potenti target treatment bronchial asthmathi paper review mechan msc treatment asthma
|
D045164;D059630;D001249
|
T061;T047;T025
|
36,325,781
|
interpret french guidelin therapeut manag bullous pemphigoid bullous pemphigoid bp common autoimmun subepiderm bullous diseaseth diagnosi bp reli clinic manifest histopatholog direct indirect immunofluoresc serolog assayin past two decad topic corticosteroid system andor topic corticosteroid major therapeut option localizedmildmoder extensivesever bp respectivelyin sever expert french studi group autoimmun bullous skin diseas collabor issu updat guidelin therapeut manag bp base evid base medicineth guidelin fulli detail updat therapeut option extens bp bp limit extent local form bp corticosteroid depend bp drug inducedassoci bpin particular system corticosteroid longer first line treatment extens bpwe interpret guidelin assist dermatologist comprehens manag bp promot standard bp treatment
|
D010391;D001327
|
T047
|
36,325,780
|
multipl correspond abnorm birth histori genet environment risk factor object investig multipl correspond genet environment risk factor abnorm birth histori provid scientif basi improv birth defect surveil system reduc incid birth defect method data collect perinat infant week old fetus day old infant born hospit obstetr depart xian result total perinat infant survey includ birth defectsth averag incid rate birth defect multipl correspond analysi show women children birth defect associ histori spontan abort famili histori birth defect histori exposur toxic harm substancesth women children birth defect show stronger associ famili histori birth defectsth birth defect women histori spontan abort rank order congenit heart diseas polydactyli neural tube defect congenit hydrocephalus cleft lip cleft palat simpl cleft lipth birth defect women given birth children birth defect follow order cleft lip cleft palat anencephali hydrocephalus neural tube defect cleft lip talip equinovarus conclus abnorm birth histori associ famili histori birth defect histori exposur environment risk factorsgiv birth three children birth defect high correl famili histori birth defect
|
D002971;D002972;D000022;D009436
|
T033;T019;T047;T046
|
36,325,779
|
relationship person trait nutrit packag feed behavior infant caregiv remot rural area sichuan provinc object analyz person trait nutrit packag feed behavior infant caregiv remot rural area sichuan provinc explor relationship method multi stage random cluster sampl method employ select infant month old caregiv remot rural area sichuan provincea structur questionnair design collect basic characterist infant caregiv well feed behavior caregiversth ten item person inventori china use evalu caregiv person trait five dimens extravers agreeabl conscienti emot stabil opennessmultivari logist regress adopt analyz relationship person trait nutrit packag feed behavior infant caregiv result total pair infant caregiv investigatedth caregiv show averag score dimens extravers agreeabl conscienti emot stabil open respectivelyth effect feed rate nutrit packag result regress analysi show premis control factor caregiv conscienti person ci p protect factor effect feed nutrit packag conclus feed behavior infant caregiv remot rural area sichuan provinc remain improv caregiv high conscienti person like feed infant effect
|
D017028;D007227
|
T061;T098;T099;T040;T097
|
36,325,778
|
clinic characterist day unplan reoper thorac surgeri object investig clinic characterist day unplan reoper thorac surgeri method retrospect analyz clinic data patient unplan reoper within day thorac surgeri peke union medic colleg hospit may may result day unplan reoper show incid median hospit stay day median hospit cost yuantwenti two patient receiv blood transfus underw intens careth period may may wit unplan reoperationsth main caus unplan reoper thorac surgeri bleed chylothorax pulmonari air leakag atelectasi gastroesophag fistula specif main caus unplan reoper patient non esophaguscardia group bleed pulmonari air leakag atelectasi chylothorax patient esophaguscardia group gastroesophag fistula incis infect poor heal bleed chylothoraxamong patient unplan reoper patient die improv recov conclus patient underw unplan reoper thorac surgeri long hospit stay high hospit cost bleed chylothorax pulmonari air leakag atelectasi gastroesophag fistula main reason unplan reoper
|
D013903;D002916;D001261
|
T047;T046;T091
|
36,325,777
|
status influenc factor hypertens elder age mianyang object understand preval influenc factor hypertens among elder age year mianyang citi sichuan provinc provid clue target prevent control hypertens method total perman resid age screen mianyang demonstr site octob april investig questionnair physic examin data person basic inform lifestyl bodi height bodi weight waist circumfer blood pressur collectedspss use descript analysi singl factor analysi logist regress analysi result preval rate hypertens elder age year mianyang specif preval rate hypertens men women respectivelyth preval rate hypertens increas increas age formula see text p multivari logist regress analysi show independ risk factor hypertens includ age year ci p age year ci p widowhood ci p divorc ci p overweight ci p obes ci p ci p histori diabet ci p histori smoke ci p histori drink ci p live urban rural fring area ci p educ background junior high school ci p low bodi weight ci p diabet histori smoke histori drink histori high risk group hypertens
|
D050177;D006973
|
T033;T047
|
36,325,776
|
effect isorhapontigenin lipopolysaccharid induc acut lung injuri mice object investig effect mechan isorhapontigenin iso protect mice lipopolysaccharid lps induc acut lung injuri ali method raw cell cultur vitro differ concentr iso viabil cell measur cck assayfurth raw cell induc ngml lps treat iso autophagi inhibitor methyladenin western blot employ determin express inflammatori cytokin interleukin il il tumor necrosi factor tnf p phospho p p p ib phospho ib p ib induc nitric oxid synthas ino cyclooxygenas cox high mobil group box hmgb autophagi marker lc beclin p reactiv oxygen speci ros product cell measur dcfh da probeth mous model ali establish intraperiton inject lps mgkg patholog chang lung tissu observ via stainingth express inflammatori cytokin autophagi marker lung tissu determin western blot content ros bronchoalveolar lavag fluid balf flow cytometri result iso regul express il il tnf ino cox hmgb inhibit ros product lps induc raw cell p furthermor promot express lc beclin inhibit express p therebi activ autophagi p howev addit regul express p pp p ib ino cox hmgb regul ib p promot product rosiso mitig patholog chang lung tissu ali miceit regul express p pp p ib ino cox hmgb regul ib lung tissu p decreas ros product balfhowev protect effect revers conclus iso may induc autophagi macrophag protect mice lps induc ali
|
D055371;D024243
|
T123;T116;T037
|
36,325,775
|
microrna carri exosom human umbil cord deriv mesenchym stem cell regul polar macrophag mous model myocardi ischemia reperfus injuri object explor role mechan microrna mir carri exosom human umbil cord deriv mesenchym stem cell huc msc regul polar macrophag mous model myocardi ischemia reperfus ir injuri method huc mscs isol cultur identifi adipogen osteogen differenti capabl determinedth exosom huc mscs separ ultracentrifug express cd cd tumor suscept gene tsg calnexin exosom determin nanoparticl track analysi softwar transmiss electron microscopi western blottingthre group huc msc mir mimic negat control design determin express mir cell exosom qrt pcrthe cblj mice random assign sham oper group ir group huc msc exosom group negat control group mir mimic groupexcept sham oper group ir model establish ligat left anterior descend arteryth echocardiographi system employ detect heart function miceh stain employ observ patholog chang mous myocardiumelisa employ determin level interleukin il tumor necrosi factor tnf arginas arg il myocardi tissueaft macrophag mous myocardi tissu isol flow cytometri employ determin express cdc cd elisa measur level il tnf arg il macrophag result huc mscs adipogen osteogen differenti capabl exosom success identifiedcompar negat control group mir mimic group show regul express mir huc mscs exosom p p compar sham oper group model ir increas left ventricular end diastol diamet lvedd p left ventricular end systol diamet lvesd p myocardi injuri score p level il p tnf p cdc p meanwhil lower left ventricular eject fraction lvef p left ventricular fraction shorten lvfs p arg p il p cd p compar ir group lvedd p lvesd p myocardi injuri score p level il p tnf p cdc p reduc lvef p lvfs p level arg p il p cd p increas huc msc exosom groupcompar negat control group lvedd p lvesd p myocardi injuri score p level il p tnf p cdc p reduc lvef p lvfs p level arg p il p cd p increas mir mimic group conclus huc msc exosom overexpress mir inhibit polar macrophag ir mous model type promot polar type
|
D055354;D059630;D035683;D015428
|
T026;T123;T025;T114;T046
|
36,325,774
|
hesperidin regul jaggednotch pathway promot macrophag polar allevi lung injuri mice bronchiol object explor effect mechan hesperidin treat lung injuri mous model respiratori syncyti virus rsv induc bronchiol method mous model rsv induc bronchiol establish balbc mice assign control group model group low dose hesperidin mgkg group high dose hesperidin mgkg group high dose hesperidin mgkg jag mgkg group random number tabl method mice group correspond dose drug administr intervent control group model group administr amount salineth bronchoalveolar lavag fluid balf sampl collect alveolar macrophag isolatedelisa employ detect level interleukin il il tumor necrosi factor tnf il balf flow cytometri detect mm polar macrophagesqrt pcr western blot respect conduct detect mrna protein level induc nitric oxid synthas ino arginas arg jag notch lung tissu result compar control group model rsv induc bronchiol elev il il tnf level increas proport type macrophag lung inflamm mucus secret score regul mrna protein level ino jag notch balf p meanwhil model lower il level decreas proport type macrophag regul mrna protein level arg p compar model group low high dose hesperidin lower il il tnf level decreas proport type macrophag lung inflamm mucus secret score regul mrna protein level ino jag notch balf p moreov hesperidin elev il level increas proport type macrophag regul mrna protein level arg p use recombin jag protein activ notch signal pathway signific attenu promot high dose hesperidin macrophag polar amelior lung inflamm damag p conclus hesperidin may allevi lung inflamm damag mice rsv induc bronchiol inhibit jaggednotch signal pathway promot type polar macrophag
|
D001988;D006569;D055370
|
T121;T127;T109;T037;T047
|
36,325,773
|
practic palliat care experi patient advanc lung cancer end life palliat care refer prevent relief physic mental suffer earli recognit activ assess manag pain pain symptom improv qualiti life patient sever diseas familiesa success case palliat care requir establish correct concept also team work improv medic systemthi paper introduc end life care experi patient advanc lung cancer show gain defici practic palliat care
|
D013727;D008175
|
T058;T191
|
36,325,772
|
feasibl efficaci train program aromatherapi palliat care object explor feasibl efficaci train program aromatherapi palliat care method data four aromatherapi train program held peke union medic colleg hospit collectedth feasibl efficaci train measur base self report questionnair traine result total valid questionnair collectedth total score program traine report program enrich theoret knowledg enhanc practic confidenceaft train traine carri aromatherapi practic fail practic main due lack appropri opportunitiessom traine suggest ad practic hour hope get follow guidanc case case basi conclus feasibl carri short term train program aromatherapi palliat care enrich traine theoret knowledg enhanc practic confidenceit necessari provid continu guidanc train increas proport traine adopt aromatherapi palliat care practic
|
D010166;D019341
|
T061
|
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