PMID
int64 35.7M
36.4M
| Title/Abstract
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36,302,130
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technic consider manag penetr cardiac injuri penetr cardiac injuri requir rapid diagnosi effici exposur nuanc technic approach within framework high coordin integr multidisciplinari care acut care surgeon strateg technic expertis ideal posit address potenti devast consequ injuri aim narrat review offer technic approach rapid evalu exposur oper repair postop care penetr cardiac injuri comprehens review cardiac trauma literatur date back provid detail toolbox approach subxiphoid pericardi window resuscit thoracotomi median sternotomi pericardiotomi aortic clamp cardiac hemorrhag control cardiac repair coronari arteri injuri pericardi closur drain placement chest wall closur damag control thorac procedur immedi postop cardiac care base fundament physiolog principl anatom consider
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D013898;D014950;D006335
|
T037
|
36,302,129
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qualiti indic oper report transan endoscop surgeri transan endoscop surgeri tes platform becom quit popular mani surgeon across countri begun excis rectal lesion use platform howev periop decis make surround excis quit variabl facilit care provid would help standard way tes report synopt oper report previous establish effect effici communic tool patient rectal cancer synopt report requir patholog radiolog major oncolog resect never previous tes use delphi process includ stakehold across canada develop tes synopt report particip submit item accord categori team characterist patient demograph preoper work lesion characterist procedur detail postop detail twenti six surgeon enter auto popul item reach final inclus allow generat synopt report templat improv periop communic patient
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D000067368;D012004;D066231
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T061;T191;T097
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36,302,128
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cost outpati versus inpati total hip arthroplasti random trial one rout mitig increas cost total hip arthroplasti tha outpati tha discharg patient day surgeri purpos studi compar cost outpati tha standard overnight stay hospit
|
D019644
|
T061
|
36,302,127
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delay discharg total hip arthroplasti associ increas risk complic purpos studi evalu influenc discharg time day complic rate follow total hip arthroplasti
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D019644
|
T061
|
36,302,101
|
sever covid among solid organ transplant recipi canada prospect multicentr cohort studi sever covid appear disproportion affect peopl immunocompromis although canadian data context limit sought determin factor associ sever covid outcom among recipi organ transplant across canada
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D000086382;D016377
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T061;T047;T067
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36,302,082
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food addict comprehens review food addict associ dysfunct reward circuit hyperrespons exposur high calori flavor overweight obes individu similar drug addict also impair self regulatori control support deregul frontostriat circuit inclus valid measur food addict clinic research yale food addict scale increas understand clinic util concept furthermor food addict eat disord obes interrel thus import recogn food addict among individu affect obes candid bariatr surgeri ie preoper postop assess context report food addict may imped weight loss increas likelihood regain weight associ person trait neurotic impuls also relat mood disord anxieti addict behavior
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D000073932;D050110;D016739
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T033;T061;T048
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36,302,081
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assess impact relationship profil test score self identifi ethnic group gender adult attach style research show subscal relationship profil test rpt relat adult attach gender differ implic find inconsist term replic limit amount research conduct ethnic differ context interperson depend studi aim bridg gap literatur term use rpt predict attach style assess gender ethnic group differ rpt score four sampl various treatment set combin yield heterogen group ethnic divers men women n mean age gender differ observ howev ethnic differ note rpt scale predict uniqu varianc secur insecur attach style studi evid increment valid rpt scale predict adult attach style consider ethnic group differ help inform treatment assess process
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D007398;D005006
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T098;T080;T055;T102;T054
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36,302,080
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self injuri covid view univers student live experi concern rais impact covid pandem individu live experi nonsuicid self injuri nssi yet effort explor accord use mix method approach sought examin whether emerg adult self injur experienc chang nssi urg behavior pandem may account chang univers student live experi nssi complet onlin question ask nssi self report chang urg behavior sinc onset covid answer open end question ask contribut chang cope timefram approxim particip report chang decreas nssi urg behavior particip discuss remov stressor eg social stress previous evok nssi well time self care develop resili account nevertheless particip report challeng amid pandem ie exacerb stress isol approxim one fifth particip report increas nssi urg behavior find add recent evid mani individu prior mental health difficulti includ nssi demonstr resili face collect advers research clinician implic discuss
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D000086382;D016728
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T055;T047;T067
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36,302,078
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differenti incid burden hiv age among women sell sex systemat review meta analysi young women sell sex ywss heighten risk hiv acquisit transmiss among least engag hiv servic insuffici epidemiolog evid character burden hiv among ywss particular compar older wss data need design tailor effect hiv prevent treatment programm popul
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D015658
|
T047
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36,302,062
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surgic correct neuromuscular scoliosi secondari congenit zika syndrom case report congenit zika syndrom czs note south american pandem zika virus peak associ sequela still describ scoliosi note patient czs howev pauciti literatur preval manag scoliosi secondari condit report case year old girl sever neuromuscular scoliosi due czs manag halo graviti traction follow growth friend construct
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D012600;D000071243;D009468;D013123;D000071244
|
T061;T019;T047;T005
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36,302,059
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collagen cross link scale passiv stiff dystroph mous muscl alter administr lysyl oxidas inhibitor duchenn muscular dystrophi dmd lack function dystrophin lead myofib instabl progress muscl damag result fibrosi fibrosi primarili character accumul extracellular matrix ecm compon chang ecm architectur fibrosi relat close function muscl stiff one architectur chang dystroph muscl collagen cross link shown increas passiv muscl stiff model fibrosi includ mdx mous model dmd test whether intraperiton inject beta aminopropionitril bapn inhibitor cross link enzym lysyl oxidas would reduc collagen cross link passiv stiff young adult mdx mice compar salin inject control found signific differ bapn treat salin treat mice collagen cross link stiff paramet howev observ collagen cross link passiv stiff scale posit dystroph muscl collagen fiber align scale passiv stiff distinct muscl also observ dystroph diaphragm show dramat fibrosi term collagen content cross link stiff overal show bapn effect reduc collagen cross link posit associ collagen cross link stiff dystroph muscl still show cross link viabl target reduc passiv muscl stiff dmd fibrot muscl condit
|
D020388;D008249
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T047;T126;T116
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36,302,058
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prism vote method individu risk predict trait genotyp data multi popul multi popul cohort offer unpreced opportun profil diseas risk larg sampl howev heterogen risk effect under complex trait across popul make integr predict challeng studi propos novel bayesian probabl framework prism vote pv construct risk predict heterogen genet data pv view trait individu composit risk subpopul stratum specif predictor form data homogen genet structur sinc individu describ composit subpopul membership framework enabl individu risk character simul demonstr pv framework appli altern predict method signific improv predict accuraci mix admix popul advantag pv enlarg genet heterogen sampl size increas two real genom wide associ data consist multipl popul show framework consider enhanc predict accuraci linear mix model five group cross valid propos method offer new aspect analyz individu diseas risk improv accuraci predict complex trait genotyp data
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D055106;D008957
|
T063;T170
|
36,302,051
|
lay concept move bewegt sein includ joy sad type implic theori research move receiv increas attent emot psycholog social emot foster bond individu within communiti increas attent howev also spark debat whether term move refer singl distinct profil emot compon rather rang differ emot profil address question investig lay concept emot compon ie elicitor cognit apprais subject feel bodili symptom consequ thoughtact bewegt sein german term move particip n provid written descript move person experi conceptu prototyp move subject content analysi obtain quantit data statist analys base latent class analys identifi two class person experi joy move sad move class move prototyp basic descript extend descript class joy move occur social valu posit relationship experi salient sad move elicit predomin negat relationship experi negat salient social valu class frequent report consequ thoughtact continu cognit engag find mean increas valuat strive connectednessprosoci basic descript prototyp includ move posit negat event instanc emot particip extend descript class also report joy sad associ emot base find addit theoret consider propos term move design emot overal posit valenc typic includ blend posit negat valenc emot compon especi weight negat compon vari emot unifi core involv feel import individu social entiti abstract social valu sourc mean one life
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D000078602;D004644
|
T041
|
36,302,050
|
data mine prothrombin time intern normal ratio refer interv children refer interv ris help physician differenti healthi sick individu prothrombin time pt intern normal ratio inr fluctuat coagul pathway defect interlaboratori variabl due instrumentreag use direct method difficult children chose indirect data mine method determin ptinr ris indirect method overcom substanti financi logist challeng ethic restrict children moreov allow partit fine grain age group prothrombin timeinr measur perform patient age birth year januari decemb retriev laboratori manag system aga khan hospit refer interv comput use indirect kosmic algorithm kosmic packag function assumpt non patholog sampl follow gaussian distribut box cox transform data follow elabor statist process isol distribut physiolog sampl mix dataset total valu retriev pt inr respect exclus patient multipl specimen obtain studi period ris calcul pt inr children stratif age group comparison th th percentil result establish ris sickkid handbook pediatr thrombosi hemostasi demonstr good agreement differ age group studi support data mine altern approach establish ptinr ris specif resourc limit set result obtain specif studi popul instrumentreag use studi also allow understand fluctuat coagul pathway increas age henc better clinic decis make base pt inr result
|
D057225
|
T066
|
36,302,049
|
psychometr biomed outcom glycat haemoglobin target set adult type type diabet protocol mix method parallel group randomis feasibl studi diseas burden diabet wide rang implic patient psycholog well health relat qualiti life glycat haemoglobin target common use guid patient manag diabet reduc futur risk develop diabet complic littl known psycholog impact glycat haemoglobin target set protocol describ studi determin feasibl evalu psycholog outcom set explicit glycat haemoglobin target peopl diabet
|
D003924
|
T047
|
36,302,048
|
pain relat fear movement dynam individu without low back pain particip weightlift andor powerlift train pain free adult general popul shown possess unhelp belief certain movement postur harm spine potenti reinforc fear avoid behaviour whether belief occur individu undertak regular powerlift pl olymp weightlift owl train unclear
|
D017116
|
T184;T047
|
36,302,047
|
percutan transhepat endoscop ultrasound guid biliari drainag malign distal bile duct obstruct use self expand metal stent studi protocol prospect european multicent trial puma trial endoscop ultrasound guid biliari drainag eus bd associ better clinic success lower rate advers event ae fluoroscopi guid percutan transhepat biliari drainag ptbd recent singl center studi main retrospect design small case number aim prospect european multicent studi compar drainag procedur use ultrasound guidanc primari metal stent implant patient malign distal bile duct obstruct puma trial
|
D002779
|
T047
|
36,302,046
|
quantit singl cell analysi leishmania major amastigot differenti demonstr variabl extend express lipophosphoglycan lpg virul factor differ host cell type immedi follow deposit mammalian host infect sand fli vector leishmania parasit encount engulf varieti cell type parasit may transit cell type primarili macrophag dendrit cell replic induc patholog time leishmania cell undergo dramat transform motil non replic metacycl stage non motil replic amastigot stage differenti process term amastigogenesi follow singl cell level identifi suit experiment landmark delin differ stage amastigogenesi qualit quantit includ new use amastigot specif marker show interest cellular local anterior posterior end compar amastigogenesi synchron infect periton bone marrow deriv macrophag pem bmm dendrit cell bmdc overal marker suit express show order transit post infect similar kinet host cell type emerg sever amastigot trait within hour follow parasit replic hour parasit bmm bmdc initi dna replic slowli lipophosphoglycan lpg leishmania virul factor facilit metacycl establish host cell declin amastigot wherea lpg express lost parasit within pem hour gt parasit infect bmm bmdc retain metacycl level lpg express hr thus l major may prolong lpg express differ intracellular environ therebi extend efficaci promot infect situ cell cell transfer parasit express key virul factor
|
D018320
|
T204
|
36,302,045
|
amelior effect half dose saffron chamomil combin psycho endocrinolog chang diabet murin model diabet mellitus chronic metabol disord increas preval worldwid reduct blood insulin level alter brain function induc oxid stress chang dopamin norepinephrin neurotransmiss ultim lead neuropsycholog symptom efficaci current avail psychotrop drug satisfactori therefor studi conduct explor benefici effect combin natur herb saffron chamomil treat diabet result neuropsycholog effect use rodent model diabet mellitus
|
D027622;D003921;D014151
|
T121;T039;T050;T002
|
36,302,042
|
dissoci rhythmic mechan enhanc memori conscious nonconsci perceptu content understand neural mechan conscious unconsci experi major goal fundament translat neurosci target earli visual cortex protocol noninvas high resolut altern current stimul particip perform delay target probe discrimin task reveal dissoci mechan mnemon process conscious unconsci perceptu content entrain rhythm bilater visual area preferenti enhanc short term memori seen inform wherea entrain region preferenti enhanc short term memori unseen inform short term memori improv frequenc specif long last result add mechanist foundat exist theori conscious call revis theori contribut develop nonpharmacolog therapeut improv visual cortic process
|
D003243;D014796
|
T041
|
36,302,041
|
unsupervis machin learn predict futur sexual behaviour sexual transmit infect among hiv posit men sex men machin learn increas introduc medic field yet limit evid benefit common use statist method epidemiolog studi introduc unsupervis machin learn framework longitudin featur evalu use sexual behaviour data last year particip swiss hiv cohort studi shcs use hierarch cluster find subgroup men sex men shcs similar sexual behaviour may appli regress test whether cluster enhanc predict sexual behaviour sexual transmit diseas stis may beyond predict convent paramet find behaviour cluster enhanc model perform accord likelihood ratio test akaik inform criterion area receiv oper characterist curv outcom studi accord bayesian inform criterion five ten outcom particular good perform predict futur sexual behaviour recurr stis thus assess methodolog use altern mean creat exposur categori longitudin data epidemiolog model contribut understand time vari risk factor
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D000072339;D012749;D015658
|
T047;T098
|
36,302,039
|
polypharmaci medic intens care unit micu admiss year caus mortal risk among hospit patient without hiv medic intens care unit micu admiss declin peopl hiv infect pwh frequenc outpati polypharmaci prescript chronic medic increas among hospit examin whether outpati polypharmaci associ subsequ year micu admiss year caus mortal associ vari hiv status
|
D019338;D015658
|
T061;T047
|
36,302,038
|
dimension morpholog awar read comprehens among chines earli adolesc reader recent research includ multipl measur morpholog awar address dimension morpholog construct context model skill read howev major studi anglocentr focus current studi aim extend previous studi logograph learner evalu dimension morpholog awar higher order read comprehens among chines adolesc reader total earli adolesc student fifth grade student sixth grade student particip studi complet seri morpholog awar measur morphem recognit morphem discrimin compound structur awar vocabulari knowledg lexic infer read comprehens test three altern path model studi show morpholog awar vocabulari knowledg best repres parallel covari predict chines read comprehens import studi highlight mediat lexic infer associ morpholog awar vocabulari knowledg read comprehens among chines reader empir find suggest morpholog awar vocabulari knowledg seem unitari construct logograph read acquisit word mean infer abil connect path morpholog awar read comprehens find contribut complex conceptu chines morpholog awar read instruct examin way morpholog construct support higher order read develop
|
D011932;D032882
|
T056;T041;T080
|
36,302,036
|
afford rfid logger monitor anim movement activ behaviour effect conserv manag strategi requir accur inform movement pattern behaviour wild anim collect data research increas turn remot sens technolog radio frequenc identif rfid rfid technolog power tool wide implement ecolog research identifi monitor uniqu individu bear substanti price tag restrict technolog generous fund disciplin project overcom price hurdl provid detail step step instruct sourc compon construct portabl rfid logger hous fraction cost commerci rfid unit assess perform rfid logger field describ applic two studi australian mammal speci monitor nest box use northern quoll dasyurus hallucatus observ forag habit quenda isoodon fuscivent feed station rfid logger perform well identifi quenda visit facilit collect individu level behaviour data includ common metric emerg time latenc approach forag effort technolog novel lower cost per unit logger enabl greater sampl size increas statist power quoll studi outlin provid solut limit design rfid logger prove innov method collect accur behaviour movement data abil success identifi individu rfid logger describ act altern complementari tool camera trap rfid logger also appli wide varieti project rang monitor anim welfar demograph trait studi anti predat respons anim person make valuabl addit modern ecologist toolkit
|
D057233
|
T073;T057
|
36,302,035
|
regress evolut effector follow host jump irish potato famin pathogen lineag order infect new host speci pathogen must evolv enhanc infect transmiss novel environ although often think evolut process accumul also process loss document exampl regress evolut effector activ irish potato famin pathogen phytophthora infestan lineag provid evid key sequenc motif effector pexrd degener follow host jump began look pexrd pexrd like sequenc across phytophthora speci found pexrd emerg common ancestor phytophthora clade b c speci sequenc analysi show key function motif c termin atg interact motif aim also acquir point lineag closer analysi show p mirabili pexrd pmpexrd aim atyp otherwis conserv central residu mutat glutam lysin aim determin whether pmpexrd aim polymorph repres adapt mirabili jalapa host environ began character jalapa atg famili find uniqu evolutionari histori compar previous character atg use co immunoprecipit isotherm titrat calorimetri assay show full length pmpexrd pmpexrd aim peptid bind weak jalapa atg combin bind assay structur model show ident residu posit pmpexrd aim polymorph underpin high affin bind plant atg final conclud function pexrd aim lost p mirabili lineag perhap owe yet unknown select pressur effector new host environ
|
D011198;D039282;D055750
|
T168;T204;T002
|
36,302,034
|
smart fus surrog model attenu refract transcrani focus ultrasound low intens focus ultrasound lifu increas appli method achiev non invas brain stimul howev transmiss ultrasound human skull substanti affect focal point characterist lifu includ dramat attenu intens refract focal point locat effect depend high dimension paramet space make effect difficult estim previous work instead focal point properti lifu experi often estim use numer simul lifu sonic skull howev procedur present mani entri barrier even comput savvi investig often requir expens comput hardwar imped lifu research present novel matlab toolbox data doidqd matlab script https doiorgzenodo rapid estim beam properti lifu transmit bone user provid specif valu frequenc lifu bone thick angl lifu appli depth lifu focal point diamet transduc use receiv estim degre refractionattenu expect given paramet
|
D014159;D012886
|
T023;T074
|
36,302,033
|
design fast onset antidepress dissoci sert nnos drn major depress disord mdd one common mental disord design fast onset antidepress work disrupt interact serotonin transport sert neuron nitric oxid synthas nnos dorsal raph nucleus drn chronic unpredict mild stress cms select increas sert nnos complex drn mice augment sert nnos interact drn caus depress like phenotyp account cms induc depress behavior disrupt sert nnos interact produc fast onset antidepress effect enhanc serotonin signal forebrain circuit discov small molecul compound zzl elicit antidepress effect hour treatment without undesir side effect compound analog reagent may serv new rapid act treatment mdd
|
D000928;D003865;D065847;D052248;D050486;D015195
|
T121;T123;T090;T116;T126;T023;T048
|
36,302,031
|
credibl stake sweden sweden legaci global leader push put climat environ heart govern decis make may come end octob first casualti countri new right wing govern ministri environ elimin day key question extent chang derail progress made toward build sustain nation world
|
D002980;D011057;D004777
|
T078;T090;T070;T067;T082;T055;T068;T057
|
36,302,030
|
big step toward mirror imag ribosom synthet protein factori could one day make durabl drug bodi ca nt break
|
D012270;D012321;D014764
|
T026;T123;T126;T116
|
36,302,026
|
monkeypox outbreak eb exact model suggest rise immun small group peopl vaccin key
|
D004196;D045908
|
T047;T067
|
36,302,025
|
fair warn swientist hunt influenza virus hog show hope cut next pandem pen
|
D007251;D009975;D058873;D000086965;D009976
|
T047;T005;T067
|
36,302,024
|
commens microbiota patient inflammatori bowel diseas produc genotox metabolit microbiota deriv metabolit elicit dna damag contribut colorect cancer crc howev full spectrum genotox chemic produc indigen gut microb remain defin establish pipelin systemat evalu genotox extens collect gut commens inflammatori bowel diseas patient identifi isol diverg phylogeni whose metabolit caus dna damag discov distinct famili genotoxin term indolimin produc crc associ speci morganella morganii non indolimin produc morganii mutant lack genotox fail exacerb colon tumorigenesi mice studi reveal exist previous unexplor univers genotox small molecul microbiom may affect host biolog homeostasi diseas
|
D015179;D004249;D000069196;D015212;D020613;D007211;D009153
|
T007;T109;T049;T131;T191;T047;T001
|
36,302,023
|
harvard studi infant monkey draw fire experi involv eyelid sutur matern separ divid scientist
|
D000882;D008426;D032761
|
T062;T015;T067
|
36,302,022
|
mirror imag transcript chiral invert ribosom function rnas synthes chiral invert ribosom goal build mirror imag biolog system requir prepar kilobas long mirror imag ribosom rnas make structur catalyt core two third molecular mass mirror imag ribosom chemic synthes kilodalton mirror imag rna polymeras enabl effici faith transcript full length mirror imag ribosom rnas enzymat assembl long mirror imag gene exploit versatil mirror imag transcript system practic applic biostabl mirror imag riboswitch sensor long term storag unprotect kilobas long l rna water l ribozym catalyz l rna polymer serv model system basic rna research
|
D012270;D016337;D012338;D012341;D014158;D004259;D014764
|
T026;T123;T116;T045;T126;T114
|
36,302,021
|
evolut antivir activ human protein retrovir origin endogen retrovirus abund compon mammalian genom descend ancient germlin infect sever mammal envelop protein encod element protect exogen virus activ document endogen express envelop human report human genom harbor larg pool envelop deriv sequenc potenti restrict retrovir infect test character envelop deriv protein suppressyn found suppressyn express human preimplant embryo develop placenta use ancestr retrovir promot cell cultur assay show suppressyn hominoid ortholog could restrict infect extant mammalian type retrovirus data support generaliz model retrovir envelop co option host immun genom defens
|
D030121;D015686;D010920;D010929;D011257;D019143
|
T123;T116;T042;T018;T005;T038
|
36,302,018
|
microbi metabolit damag dna unexpect member gut microbiota produc divers host cell genotoxin
|
D015179;D004249;D000069196;D020613;D009153
|
T007;T049;T131;T191;T001
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36,302,017
|
forgotten ebola vaccin could help outbreak merck unearth frozen batch experiment vaccin made year ago
|
D004196;D046129;D029043;D019142;D035703
|
T061;T129;T121;T067;T109;T005;T047
|
36,302,012
|
attenu evolut mammal cenozo cenozo diversif placent mammal archetyp adapt radiat yet discrep molecular diverg estim fossil record fuel ongo debat around time tempo driver radiat analysi three dimension skull dataset live extinct placent mammal demonstr evolutionari rate peak earli attenu quick long term declin tempo punctuat burst innov decreas amplitud past million year social precoci aquat herbivor speci evolv fastest especi whale eleph sirenian extinct ungul slow rate rodent bat indic dissoci taxonom morpholog diversif frustrat high similar ancestr shape estim placent mammal superord suggest earliest repres may continu elud unequivoc identif
|
D005075;D000073566;D012886
|
T045;T023;T015
|
36,302,008
|
burst skull evolut weaken time skull shape mammal diversifi rapid earli histori
|
D005075;D008322;D012886
|
T045;T023;T015
|
36,302,006
|
steal gene face consequ human genom contain domest viral envelop gene antivir activ
|
D030121;D015752;D015894;D011257
|
T123;T005;T116;T028
|
36,302,005
|
spermidin activ mitochondri trifunct protein improv antitumor immun mice spermidin spd delay age relat patholog various organ spd supplement overcam impair immunotherapi tumor age mice increas mitochondri function activ cd cell treatment nave cd cell spd acut enhanc fatti acid oxid spd conjug bead bound mitochondri trifunct protein mtp mtp complex synthes purifi escherichia coli spd bound subunit mtp strong affin alloster enhanc enzymat activ cell specif delet mtp subunit abolish enhanc program cell death protein pd blockad immunotherapi spd indic mtp requir spd depend cell activ
|
D018414;D008928;D063992;D063993;D013095;D009369
|
T026;T123;T116;T025;T109;T191;T126;T043
|
36,301,999
|
role religi leader use hivaid prevent strategi among young peopl lira district uganda young peopl year bear highest burden new infect particular vulner high riski behavior earli sexual activ pauciti inform role religi leader multi sector fight hivaid examin role religi leader use hiv prevent strategi among young peopl
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D000163;D015658
|
T047
|
36,301,997
|
venus effici virus infect detect fusion site discoveri method use singl cell bulk rna seq data earli accur detect virus clinic environment sampl essenti effect public healthcar treatment therapeut pcr detect potenti pathogen high sensit difficult scale requir knowledg exact sequenc pathogen advent next gen singl cell sequenc possibl scrutin viral transcriptom finest possibl resolut cell newfound abil investig individu cell open new avenu understand viral pathophysiolog unpreced resolut leverag abil propos effici accur comput pipelin name venus virus detect integr site discoveri singl cell bulk tissu rna seq data specif venus address two main question whether tissuecel type infect virus virus interest infect whether virus insert human genom analysi broken two part valid discoveri first valid appli venus well studi viral dataset hbv hepatocellular carcinoma hiv infect treat antiretrovir therapi second discoveri analyz dataset hiv infect neurolog patient deepli sequenc cell detect viral transcript novel target brain high confid integr site immun cell conclus describ venus public avail softwar believ valuabl virus investig tool scientif communiti larg
|
D018536;D014780;D015658;D008113
|
T083;T191;T005;T047
|
36,301,995
|
baselin oxygen consumpt decreas cortic depth cerebr cortex organ cortic layer differ cellular densiti composit wire cortic laminar architectur also readili reveal stain cytochrom oxidas last enzym respiratori electron transport chain locat inner mitochondri membran hypothes high densiti band cytochrom oxidas cortic layer iv reflect higher oxygen consumpt baselin unstimul condit test hypothesi use direct measur partial pressur po cortic tissu mean photon phosphoresc lifetim microscopi plm revisit previous develop method extract cerebr metabol rate cmro base photon po measur around dive arteriol appli method estim baselin cmro awak mice across cortic layer surpris result reveal decreas baselin cmro layer layer iv decreas cmro cortic depth parallel increas tissu oxygen higher baselin oxygen cytochrom densiti layer iv may serv reserv surg neuron activ certain metabol activ brain state rather reflect baselin energi need studi provid knowledg first quantif microscop resolv cmro across cortic layer step toward better understand brain energi metabol
|
D003576;D010101
|
T201;T126;T116
|
36,301,992
|
comput model color percept biolog plausibl spike neural network biolog plausibl comput model visual percept potenti link high level visual experi under neuron spike dynam work propos neuromorph brain inspir spike neural network snn driven model reconstruct color imag retin input compar result experiment obtain v neuron activ map macaqu monkey use voltag sensit dye imag use model demonstr critic explor color constanc color assimil ambigu color percept parametr implement allow critic evalu visual phenomena singl biolog plausibl comput framework use parametr combin high low pass imag filter snn base fill poisson process provid adequ color imag percept account differ individu percept
|
D003118;D016571
|
T170;T041
|
36,301,991
|
investig free roam dog popul gastrointestin parasit divers tulm mxico free roam domest dog cani lupus familiari pose major conserv public health risk worldwid better understand threat domest dog wildlif peopl add grow literatur free roam dog ecolog studi conduct estim dog popul tulm mxico modifi mark recaptur techniqu program mark use obtain dog popul estim along six differ transect divid citi popul estim rang dog one transect dog anoth total dog identifi throughout studi estim minimum popul densiti dogskm fecal sampl also opportunist collect parasit identif fecal flotat analysi use mcmaster techniqu sampl collect test posit gastrointestin parasit common speci found ancylostoma caninum follow toxocara cani dipylidium caninum cystoisospora spp parasit load rang ova per gram fece larg popul free roam dog preval three zoonot parasit highlight import understand free roam dog ecolog educ public health risk free roam dog pose los perro callejero cani lupus familiari representan un gran riesgo para la conservacin de animal la salud pblica mundialment para comprend mejor la amenaza que significan los perro domstico para la fauna silvestr los humano aportar la crecient bibliografa sobr la ecologa de los perro callejero se realiz una investigacin para estimar la poblacin de los perro en tulm mxico se utiliz una tcnica modificada de marcado recaptura junto con el programa mark para estimar la poblacin canina en sei transecto de la ciudad los estimado varan desd perro en un transecto hasta en otro con un total de perro identificado en el transcurso de la investigacin una densidad mnima estimada de perroskm adem se hizo una recoleccin oportunista de muestra de hece para la identificacin de parsito por medio del anlisi de flotacon fecal con el mtodo mcmaster de las muestra recolectada resultaron positiva para parsito gastrointestinal de las cual las especi ms comun fueron ancylostomoa caninum seguida por toxocara cani dipylidium caninum cystoisospora spp las carga parasitaria variaron desd hasta vulo por gramo de hece la alta poblacin de perro callejero la prevalencia de tres enfermedad zoontica resaltan la importancia de entend la ecologa de los perro callejero educar al pblico sobr los riesgo que significan los perro callejero para la salud
|
D010271;D019596
|
T015;T204
|
36,301,990
|
water treatment point use treatment prefer among household ethiopia contemporan systemat review meta analysi water essenti maintain human life health digniti untreat water consumpt caus million death annual happen develop nation includ children point use water treatment enabl peopl without reliabl access safe drink water reduc contamin minim microbi risk level systemat review meta analysi therefor use identifi select critic apprais relev evid water treatment practic associ factor among ethiopian household
|
D060766;D018508
|
T052;T167;T057
|
36,301,988
|
participatori peer research explor experi learn covid alli health healthcar scienc student teach learn experi alli health healthcar scienc student alter covid pandem limit research explor experi futur healthcar workforc use participatori research design aim studi explor impact global pandem clinic academ experi healthcar student use co product approach student peer research
|
D000086382
|
T047;T067
|
36,301,987
|
aqueous solut contain net charg solut high ph valu sometim thought contain net negat charg excess oh group solut low ph valu thought opposit follow specul use simpl electrochem cell studi three type solut electrolyz water differ ph valu acid base differ ph valu various salt solut electrolyz water various ph valu test water ph found acid water inde posit charg basic water negat charg found much standard acid base compar refer solut acid solut posit charg basic solut negat charg various salt includ nacl kcl naso kso also test di water contain trace amount nacl lend conduct surpris salt found negat charg concentr increas collect result support hypothesi least aqueous solut may contain net charg
|
D012492;D012965
|
T121;T104;T196;T197;T130
|
36,301,986
|
assess health staff profici qualiti key malaria indic rural district ghana routin health inform system rhis import sure enough control malaria elimin well system work extens provid accur data report malaria case instead present model approxim malaria burden queri rais qualiti use generat malaria data issu concern includ inaccur report malaria case well treatment plan wrong categor malaria case regist use collat data misplac data regist report studi analys data qualiti concern health staff profici timeli avail data accuraci sissala east municip health director mhd
|
D008288
|
T047
|
36,301,985
|
anthropogen nois may impair mate behaviour shore crab carcinus maena anthropogen nois recent addit list human made threat environ potenti establish negat impact wide rang anim despit econom ecolog signific studi consid impact anthropogen nois crustacean though past studi shown caus signific effect crustacean physiolog anatomi behaviour mate behaviour crustacean could potenti sever affect anthropogen nois given nois demonstr impact crustacean abil detect respond chemic visual acoust cue vital courtship ritual explor nois impact crustacean mate test respons male green shore crab carcinus maena southwest uk coast expos ship nois record simultan present dummi femal soak femal sex pheromon uridin diphosph udp experiment tank setup record treatment n control treatment n found signific negat effect nois occurr mate behaviour compar nois condit though signific effect nois time took crab respond pheromon effect suggest reproduct impair due anthropogen nois could potenti contribut decreas crustacean popul subsequ ecolog econom repercuss given find preliminari studi research undertaken includ larger sampl size doubl blind setup control laboratori trial order fulli extrapol potenti impact nois mate natur environ
|
D003386;D009622;D012724
|
T123;T067;T069;T204
|
36,301,984
|
cost analysi chronic pain due musculoskelet disord chile magnitud cost chronic pain matter concern mani countri worldwid high preval cost impli health system product absente need address urgent studi begun describ problem chile still debt highlight import urgenc contribut chronic pain financi coverag studi object estim expect cost chronic pain relat musculoskelet diseas chilean adult popul conduct mathemat decis model exercis markov model estim cost consequ patient classifi sever moder mild pain group restrict five diseas knee osteoarthr hip osteoarthr lower back pain shoulder pain fibromyalgia data analysi consid set transit probabl estim total cost sick leav payment product loss result show total annual cost chronic pain chile usd correspond five diseas studi highest cost relat therapeut manag follow product loss sick leav day low back pain fibromyalgia costlier chronic pain relat musculoskelet diseas conclud magnitud cost countri approach chronic pain relat increas product loss sick leav payment incorpor action ensur access financi coverag new care strategi reorgan care deliveri integr comprehens care could potenti impact cost patient health system final impact covid pandem probabl deepen even problem
|
D059350;D005356;D000086382;D017116;D009140
|
T184;T047;T067
|
36,301,983
|
onlin parent train platform complementari treatment disrupt behavior disord attent deficit hyperact disord random control trial protocol attent deficithyperact disord adhd associ divers impair opposit defiant disord odd frequent comorbid parent train evid base intervent seem effect reduc externalizingdisrupt behavior possibl lead better prognosi clinic trial aim evalu effect onlin parent train model complementari treatment adhd odd
|
D001289
|
T048
|
36,301,982
|
respons toward eyefluk diplostomum pseudospathaceum differ genet lineag rainbow trout marker assist select breed fish higher level resist toward specif pathogen may improv fish health impact host genotyp suscept multipl pathogen infect still poor investig studi examin resist rainbow trout oncorhynchus mykiss toward infect eye fluke diplostomum pseudospathaceum use genet select rainbow trout carri snps associ resist toward parasit ciliat ichthyophthirius multifilii expos fish eye fluke cercaria show fish part resist multifilii suscept eye fluke invas express immun relev gene encod innat adapt factor also affect genotyp respond less strong secondari fluke infect complex genom architectur diseas resist toward multipl pathogen discuss
|
D017686;D005393;D014200;D016803;D014201
|
T047;T204;T013
|
36,301,981
|
embodi time effect read expertis spatial represent past futur peopl grasp abstract concept time argu abstract concept futur past ground sensorimotor experi respons word refer past futur either spatial compat incompat left right timelin space time congruenc effect observ present studi investig whether read expertis determin strength space time congruenc effect would suggest learn read write drive effect use tempor categor task compar two type space time congruenc effect one spatial incongru generat locat stimuli screen one generat locat respons keyboard first type incongru visuo spatial second involv motor system result show stronger space time congruenc effect second type incongru ie motor system involv first type visuo spatial crucial read expertis measur standard read test predict size space time congruenc effect altogeth result reinforc claim spatial represent time partial mediat motor system partial ground spatial direct movement read write
|
D011932;D013998
|
T056;T041
|
36,301,980
|
associ fundament motor skill compet isometr plank modifi pull up year old children observ analysi nhane nyf purport relationship fundament motor skill fms health relat physic fit physic activ obes among children purpos observ secondari data analysi examin associ children nation youth fit survey nyf five year old children femal nyf databas complet test gross motor develop nd edit tgmd muscular fit measur plank modifi pull up weight status base bodi mass index bmi percentil signific posit correl identifi tgmd score pull up plank linear regress model control sex weight status hispan ethnic also identifi modifi pull up complet plank time signific predictor tgmd total raw score demograph factor signific factor model secondari data analysi identifi associ fms health relat physic fit ie muscular fit modifi pull up plank perform five year old children result underscor import differ facet health relat physic fit contribut signific fms perform need work relat physic fit preschool age children
|
D009048;D015444
|
T061;T056;T040
|
36,301,979
|
sickl cell diseas among latinx california african american latinx second largest popul affect sickl cell diseas scd us howev research larg ignor devast rare blood disord specif affect latinx nationwid
|
D000755
|
T047
|
36,301,977
|
effect covid vaccin covishieldtm covaxin healthcar worker mumbai india retrospect cohort analysi india start vaccin programm coronavirus infect covid januari covishieldtm oxfordastra zeneca vaccin manufactur serum institut india covaxin bharat biotech india design present studi studi effect vaccin covid prevent breakthrough infect sever symptomat case among health care worker real life scenario mumbai india furthermor also want studi factor associ effect
|
D000086663;D000086382
|
T200;T047;T067
|
36,301,976
|
prior antibiot risk subsequ herp zoster popul base case control studi effect antibiot human microbiom well establish indirect effect relat immun respons less clear possibl associ herp zoster involv reactiv previous varicella zoster virus infect prior antibiot exposur might indic potenti link immun respons
|
D006562;D002644
|
T047
|
36,301,975
|
gaze percept head pupil rotat typic develop impact autism spectrum disord studi gaze percept larg focus singl cue eye two dimension set literatur suggest gaze percept shape atyp develop autism spectrum disord asd gaze percept realiti contextu sensit perceiv emerg featur convey rotat pupil head examin gaze percept integr context across develop among children adolesc develop typic asd stimuli found group util head pupil rotat judg gaze face evalu gaze physic present robot asd observ use eye cue less typic develop peer demonstr emerg gaze percept slowli develop process surpris intact albeit weaken asd illustr new technolog bridg visual clinic scienc
|
D000067877
|
T048
|
36,301,974
|
reliabl valid perceiv stress scale bangladesh valid studi conduct world item perceiv stress scale pss becom robust wide use instrument assess apprais stress present studi aim valid test psychometr properti pss bangladeshi popul three hundr fifteen adult age year eight division district bangladesh particip studi good fit two factor structur scale indic multipl indic df root mean squar error approxim compar fit index standard root mean squar residu confirmatori factor analysi full scale demonstr intern consist test retest reliabl construct valid two factor also demonstr accept psychometr properti psychometr properti bengali pss demonstr studi suggest pss valid reliabl instrument use bangladesh among bengali speak popul
|
D013315
|
T048
|
36,301,973
|
medic student well assess beyond anxieti depress scope review signific increas distress mental health ill identifi medic student train result medic school attempt understand factor link well well questionnair present use approach identifi student risk factor mental health provid appropri resourc support referr studi aim identifi valid questionnair literatur measur medic student well
|
D013337;D002055
|
T097;T048
|
36,301,972
|
annona muricata l peel extract inhibit carbohydr metabol enzym reduc pancreat cell inflamm apoptosi via upregul pikakt gene annona muricata l peel recogn mani ethnobotan use includ diabet manag howev limit detail scientif inform mechan antidiabet activ exist object studi evalu anti diabet properti aqueous extract muricata peel aeamp mechan action alloxan induc diabet rat
|
D031041;D003921;D007004;D010936
|
T121;T123;T050;T039;T002
|
36,301,971
|
attitud univers hospit staff toward hous assist suicid investig staff attitud toward assist suicid hospit set switzerland
|
D017236
|
T054
|
36,301,970
|
treatment pattern outcom light chain amyloidosi institut registri amyloidosi report argentina light chain al amyloidosi form system amyloidosi caus organ dysfunct main affect heart kidney patient tailor risk adapt decis make critic al amyloidosi manag limit real world evid data argentina latin america regard treatment approach al amyloidosi retrospect cohort studi aim describ treatment pattern outcom adult patient year diagnos al amyloidosi hospit italiano bueno air argentina use yearfollow data june may institut registri amyloidosi ira studi popul mean age year weremal heart kidney frequent affect organ elig patient includ studi underw treatment bortezomib base regimen prefer first line treatment patient overal patient present deep respons complet good partial respons median overal surviv os year year os progress free surviv rate confid interv ci ci respect studi provid vital real world evid long term treatment pattern surviv larg cohort al amyloidosi patient argentina
|
D000075363;D000686
|
T047;T191
|
36,301,969
|
protocol educ program infect preventioncontrol medic healthcar student systemat review meta analysi covid pandem infect protectioncontrol educ becom increas import healthcar profession also student undertak medic nurs physic therapi occup therapi relat cours review literatur infect control educ reveal target particip often compris healthcar worker studi infect control educ focus student develop protocol systemat review literatur simul base infect preventioncontrol educ student undertak medic nurs rehabilit relat cours protocol systemat review meta analysi draft align prefer report item systemat review meta analysi prisma statement systemat literatur search perform period januari septemb use central medlin scopus databas qualit quantit examin effect simul base infect educ student systemat review meta analysi two investig independ search databas accord defin search strategi full text select articl screen independ keep mind inclus criteria pair review descript data extract studi regard studi design method particip outcom meta analysi perform quantit data suitabl heterogen assess use standard odd ratio categor data weight mean differ continu data confid interv calcul use analysi statist pool possibl find quantit paper present narrat form qualit aspect employ narrat descript synthesi review make valuabl contribut domain simul base infect preventioncontrol student enrol medic andor relat cours
|
D000086382;D058873
|
T047;T067
|
36,301,968
|
hypoxia toler low ph toler associ latitudin cline across popul tigriopus californicus intertid organ must toler daili fluctuat environment paramet repeat exposur co occur condit may result toler multipl stressor correl intertid copepod tigriopus californicus experi diurnal variat dissolv oxygen level ph oppos process photosynthesi cellular respir lead coordin high day low night environment paramet overlap spatial gradient frequent result correl trait less attent given explor tempor correl stressor investig whether hypoxia toler correl low ph toler separ test hypoxia low ph stress toler separ genet differenti popul californicus independ check similar toler two stressor latitud sex size time sinc collect predictor found although hypoxia toler correl latitud low ph toler predictor signific stressor conclud tempor coordin exposur low ph low oxygen result popul develop equival toler although climat chang alter sever environment variabl simultan organ abil toler chang may similar coupl
|
D033342
|
T204
|
36,301,967
|
deciph mechan anhydrobiosi entomopathogen nematod heterorhabd indica compar transcriptom entomopathogen nematod heterorhabd indica popular biocontrol agent high commerci signific possess tremend genet architectur surviv desicc stress undergo anhydrobiosi increas lifespan attribut exploit formul technolog compar transcriptom unstress anhydrobiot h indica reveal sever previous conceal metabol event crucial adapt toward moistur stress induct anhydrobiosi infect juvenil ij transcript upregul downregul strategi toward anhydrobiot surviv ij show activ sever gene critic antioxid defens detoxif pathway signal transduct unfold protein respons molecular chaperon ubiquitin proteasom system differenti express sever gene involv gluconeogenesi oxid fatti acid glyoxyl pathway glyceroneogenesi fatti acid biosynthesi amino acid metabol shikim pathway sachharopin pathway kyneurin pathway lysin biosynthesi one carbon metabol polyamin pathway transsulfur pathway folat cycl methionin cycl nucleotid biosynthesi mevalon pathway glyceraldehyd phosphat dehydrogenas also observ report role shikim pathway sachharopin pathway glyceroneogenesi anhydrobiot seven class repeat protein specif h indica first time result provid insight anhydrobiot surviv strategi util strengthen develop novel formul enhanc sustain shelf life
|
D059467;D009348
|
T081;T204;T086
|
36,301,966
|
age predict coronari angiographi use deep neural network age potenti label extract prognosi relat imag featur coronari angiographi cag still consid refer standard coronari arteri assess especi treatment acut coronari syndrom ac although age caus chang coronari arteri age relat imag featur cag prognost relev fulli character hypothes deep neural network dnn model could train estim vascular age use cag age predict cag could show signific associ clinic outcom ac dnn train estim vascular age use ten separ frame cag video patient test cag video patient subsequ ac patient underw percutan coronari intervent pci analys assess whether predict age dnn associ clinic outcom age predict continu variabl show mean absolut error year r squar r among ac patient stratifi predict age cag imag pci major advers cardiovascular event mace frequent observ older vascular age group younger vascular age group p furthermor control actual age gender peak creatin kinas histori heart failur older vascular age group independ suffer mace hazard ratio ci p vascular age estim base cag imag dnn show high predict valu age predict cag imag dnn could signific associ clinic outcom patient ac
|
D062645;D054058
|
T061;T047
|
36,301,965
|
assess student prefer method assess experienti learn best worst scale approach transit tradit person classroom format onlin instruct deliveri method onlin student assess covid pandem signific challeng effect teach learn evalu although grow literatur assess relat efficaci differ onlin teach techniqu previous literatur analyz student perspect method prefer evalu perform experienti learn cours student perceiv assess method critic affect learn experi academ achiev better understand student prefer assess method best worst scale approach use two onlin survey undergradu student enrol experienti learn base program covid pandem analysi student respons indic student highest level support assess emphas develop critic think skill profession skill case studi student would prefer assess drive develop differ skill creativ think realist develop skill transfer real world prefer assess fast involv littl time frequent safe prevent measur elimin cheat strateg high probabl get good grade
|
D018794;D000086382
|
T065;T047;T067
|
36,301,964
|
prospect cohort studi dynam cell free dna elev cardiac surgeri cardiopulmonari bypass cardiac surgeri cardiopulmonari bypass cpb associ system inflammatori reaction occasion induc life threaten organ dysfunct caus dysregul host respons damag associ molecular pattern damp sever inflamm cell free dna cfdna histon releas inflammatori cell damag tissu act damp sought character chang circul cell free dna cfdna level cpb primari outcom renal failur ventil time hr length stay los intens care unit icu hr hospit los day death look associ blood test comparison standard score prospect cohort studi enrol patient undergo non emerg coronari arteri bypass graft blood drawn baselin minut cpb cross clamp remov minut chest closur cfdna measur fast fluoresc method baselin cfdna level ngml increas surgeri peak cross clamp remov ngml return baselin recoveri differ cfdna minut cpb cfdna invers correl peripher vascular diseas pvd longer ventil time longer icu hospit length stay los receiv oper characterist roc curv cfdna long icu los hr area curv auc p roc auc cfdna long hospit los day p correct time cpb multivari logist regress model improv roc auc p suggest cfdna independ risk factor conclud measur paramet includ sts euroscor predict power cfdna highest thus measur cfdna may enabl earli monitor patient higher risk studi mechan behind negat associ cfdna pvd outcom warrant
|
D000073888;D006348
|
T061;T123;T114
|
36,301,963
|
diagnost accuraci comput tomographi adult suspect acut append emerg depart privat tertiari hospit tanzania increas incid acut append sub saharan africa emphas need accur reliabl diagnost tool howev variabl diagnost perform comput tomographi suspect acut append coupl compar higher negat appendectomi rate set highlight possibl concern regard diagnost accuraci studi evalu diagnost accuraci comput tomographi scan suspect acut append emerg depart tanzania
|
D001064
|
T047
|
36,301,962
|
explor person psychotherapi depress system dynam approach depress disord lead contributor medic disabl yet depress patient receiv adequ treatment given year respons treatment vari wide among individu depress poor respons one treatment signal poor respons other fact half patient recov first line psychotherapi recov second option attempt person psychotherapi patient characterist produc better outcom usual care research person psychotherapi still infanc present studi explor new method person psychotherapi depress simul model studi develop system dynam simul model depress base one major mechan depress literatur investig trend depress symptom differ condit treatment simul output show import individu servic appropri time reveal new method person psychotherapi heterogen individu futur research need expand model includ addit mechan depress
|
D003863;D011613
|
T061;T184;T048
|
36,301,961
|
homocystein thiolacton contribut prognost valu fibrin clot structurefunct coronari arteri diseas fibrin clot structurefunct contribut cardiovascular diseas examin sulfur contain metabolit determin fibrin clot lysi time clt maximum absorb absmax relat outcom coronari arteri diseas cad patient effect b vitaminfol therapi clt absmax studi plasma sampl collect cad patient random x factori design folic acid vitamin b b ii folic acid vitamin b iii vitamin b iv placebo year western norway b vitamin intervent trial clot lysi time clt maximum absorb absmax determin use valid turbidimetr assay acut myocardi infarct ami mortal assess year follow data analyz use bivari multipl regress surviv free event studi use kaplan mayer plot hazard ratio hr confid interv ci estim use cox proport hazard model baselin urinari homocystein uhci thiolacton plasma cystein cys signific associ clt plasma total hci signific associ absmax independ fibrinogen triglycerid vitamin e glomerular filtrat rate bodi mass index age sex plasma creatinin crp hdl c apoa previous diseas b vitaminsfol affect clt absmax kaplan meier analysi show associ increas baselin clt absmax wors outcom cox regress analysi baselin clt absmax cutoff predict ami clt hr ci p absmax hr ci p mortal clt hr ci p absmax ci p adjust prognost biomark associ remain signific cys uhci thiolacton thci signific predictor ami cox regress model includ clt conclus uhci thiolacton plasma cys novel determin clt import predictor advers cad outcom clt absmax affect b vitaminfol therapi could account lack efficaci therapi cad trial registr url http clinicaltrialsgov identifi nct
|
D003324;D014803;D009203;D013927
|
T121;T127;T109;T047;T046
|
36,301,960
|
clinic histopatholog studi renal biopsi nepales children singl center experi glomerular diseas import caus morbid mortal among children develop countri renal biopsi gold standard determin histolog diagnosi prognosi therapi option studi aim investig clinic histopatholog direct immunofluoresc find renal biopsi result nepales children year old
|
D009404;D008181;D007674;D009402;D005921;D005922
|
T047
|
36,301,959
|
healthcar claim base lyme diseas case find algorithm unit state systemat literatur review lyme diseas ld fifth common report notifi infecti diseas unit state us approxim case report via public health surveil howev healthcar claim base studi estim number ld case time larger report surveil assess burden ld use healthcar claim data effect intervent ld prevent treatment import use valid well perform ld case find algorithm ld algorithm conduct systemat literatur review identifi ld algorithm use us healthcar claim data valid status
|
D000465;D008193
|
T047;T170
|
36,301,957
|
qualiti improv manag patient non muscl invas bladder cancer introduc surgic checklist transurethr resect bladder tumor qualiti transurethr resect bladder tumor turbt mark vari among surgeon may consider impact treatment outcom import surgic checklist turbt suggest order standard procedur improv surgic oncolog outcom present studi verifi use checklist manag patient non muscl invas bladder cancer nmibc
|
D001749
|
T191
|
36,301,956
|
preval associ risk factor malaria among febril five children visit health facil ziquala district northeast ethiopia multicent cross section studi malaria among lead caus mortal morbid among five children develop countri ethiopia set target control elimin malaria risk group intervent howev diseas remain serious public health concern endem area like wollo northeast ethiopia therefor studi aim determin malaria preval risk factor parasit densiti among five children ziquala district
|
D008288;D016780;D016778
|
T047
|
36,301,955
|
influenc largest privat sharehold bank loan evid china point largest privat sharehold use inform advantag industri influenc bank industri lend behavior use sampl chines citi commerci bank find increas ownership stake largest privat sharehold lead bank lend industri interest largest state own sharehold effect import confirm channel inform advantag analyz bank industri npl ratio list compani maximum loan amount bank cours effect largest privat sharehold achiev interven board decis addit ownership structur influenc effect
|
D007221;D010067
|
T078;T081;T057
|
36,301,954
|
consent confound factor prospect observ studi critic ill elder patient analysi prospect multin observ studi critic ill patient year age vip studi also studi effect differ countri consent studi inclus post hoc analysi icus analyz accord requir studi consent group icus countri requir consent admiss defer consent survivor group b icus form activ consent admiss necessari either patient surrog patient characterist sever diseas outcom variabl compar total patient includ countri median age year iqr england includ chang criteria consent studi period group countri patient group b countri patient compar age gender distribut cognit better preserv prior admiss group b group suffer organ dysfunct admiss compar group b sequenti organ failur assess score median respect icu surviv lower group compar group b p henc found profound effect outcom accord differ obtain consent studi seem sever ill elder patient less often recruit studi group b henc outcom measur surviv higher group therefor conclud consent like import confound factor outcom evalu intern studi focus old patient
|
D016638;D063305
|
T033;T047;T081
|
36,301,953
|
stress viral insult trigger ek prp convers human cerebr organoid prion diseas group rare transmiss invari fatal neurodegen diseas affect human anim caus diseas misfold prion protein patholog isoform call prion human prion diseas case genet ek mutat caus famili creutzfeldt jakob diseas cjd preval sporad genet diseas remain uncertain initi protein misfold trigger prior studi link protein misfold oxid stress insult deregul interact cellular cofactor viral infect previous work develop cerebr organoid co model use human induc pluripot stem cell contain ek mutat cos three dimension human neural tissu permit studi host genet environment factor contribut diseas onset isogen match cos without ek mutat use investig propens ek prp misfold follow cellular insult associ oxid stress sinc viral infect also associ oxid stress neurodegen diseas addit investig influenc herp simplex type virus hsv neurotrop virus establish life long latent infect host ek prp misfold cos prove high infect hsv neither acut latent infect direct oxid stress insult result evid ek prion misfold conclud misfold seed activ prp speci readili induc oxid stress hsv organoid system
|
D007562;D057026;D000085343;D017096;D011328
|
T025;T116;T005;T047;T046
|
36,301,952
|
compass fatigu among frontlin healthcar worker covid pandem tunisia healthcar worker hcws high vulner compass fatigu cf lead decreas mental physic health also deterior safeti care deliv studi aim measur compass satisfact cs cf level predictor among tunisian hcws
|
D000068376;D000086382;D002055
|
T047;T067;T048
|
36,301,951
|
ethiopian communiti base health insur afford willing pay analysi among household south central ethiopia communiti base health insur cbhi voluntari prepay mechan guarante provis basic healthcar servic without financi barrier underserv segment popul develop countri govern ethiopia launch cbhi program protect communiti high pocket health expenditur improv health servic util decad ago howev improv qualiti healthcar servic deliveri health facil cover chang cost healthcar govern revis contribut cbhi scheme therefor determin willing pay cbhi scheme associ factor among rural household lemu bilbilo district south central ethiopia
|
D000080051
|
T058
|
36,301,950
|
generat human colon organoid healthi inflammatori bowel diseas mucosa ulcer coliti crohn diseas chronic inflammatori bowel diseas ibd unknown caus character relaps remit behavior grow evid support idea epitheli barrier play central role pathogenesi ibd well evolut time thus repres potenti target novel therapeut option last decad introduct epitheli cultur ex vivo expand intestin adult stem cell asc impact abil studi function epithelium sever gastrointestin disord includ ibd describ detail reproduc protocol generat matrigel embed epitheli organoid asc non ibd ibd donor use small colon biopsi includ step optim slight modifi version protocol also provid case surgic sampl use method epitheli organoid expand sever passag therebi generat larg quantiti viabl cell use multipl downstream analys includ genet transcript proteom andor function studi addit cultur generat use protocol suitabl establish cultur model relev cell cell interact occur ibd mucosa
|
D015212;D003093
|
T047
|
36,301,949
|
potenti eye track simul softwar analyz landscap prefer profound knowledg landscap prefer high import support decis make particular context emerg socio econom develop foster sustain spatial develop mainten attract landscap eye track experi increas use examin respond observ landscap studi time consum cost first time studi explor potenti use eye track simul softwar mountain landscap identifi type inform obtain eye track simul examin inform contribut explan landscap prefer base panoram landscap photograph repres major landscap type central european alp studi collect indic describ characterist hotspot identifi visual attent softwar vas indic includ quantit spatial inform eg number hotspot probabl initi view hotspot well variabl indic natur artifici featur within hotspot eg cloud light condit natur anthropogen featur addit estim variabl describ photo content calcul landscap metric quantifi spatial pattern result indic averag hotspot identifi per photograph most contain singl tree tree trunk build horizon transit use backward stepwis linear regress model hotspot indic increas model explanatori power thus find indic analysi eye track hotspot support identif import element area landscap limit explain prefer across differ landscap type futur research therefor focus specif landscap characterist complex structur visual appear specif element increas depth inform obtain eye track simul softwar
|
D000084542;D012984
|
T060;T090;T170;T073
|
36,301,948
|
lymphocyt specif protein tyrosin kinas specif inhibitor attenu lung fibrosi via suppress tgf product regulatori cell lymphocyt specif protein tyrosin kinas lck member src famili tyrosin kinas signific lck inhibit lung fibrosi yet fulli elucid even though lung fibrosi common preced inflamm caus infiltr cell express lck studi examin effect lck inhibit experiment mous model lung fibrosi also evalu effect lck inhibit express tgf inhibitori cytokin regul immun function regulatori cell treg
|
D011658
|
T047
|
36,301,947
|
healthcar util children across care continuum covid pandem healthcar util decreas covid pandem like due reduc transmiss infect healthcar avoid though various investig describ chang pattern children analyz specif care set compar healthcar util prescript diagnosi pattern children across care continuum first year pandem preced year
|
D058873;D000086382
|
T047;T067
|
36,301,946
|
intra individu impact covid pandem mental health sleep young adult covid pandem pose uniqu academ social financi health relat challeng young adult numer studi document averag increas report mental health issu general popul measur magnitud chang mental health symptom sleep difficulti within individu measur impact covid pandem mental health sleep univers student pre mid pandem prior pandem fall individu n recruit particip eight day comprehens sleep studi use fitbit actigraphi particip also complet detail mental health sleep survey includ depress bdi ii anxieti stai sleep disturb promi survey one year later individu repeat studi pandem fall particip complet origin survey sleep studi addit target survey mental sleep health due pandem self report level anxieti depress sleep disturb sleep paramet measur actigraphi compar within individu pre mid pandem self report survey data reveal three quarter particip experienc increas stress anxieti due pandem addit intra individu depress anxieti symptom increas clinic signific level within individu pre mid pandem two third particip report sleep less half report sleep health worsen pandem chang sleep disturb posit associ chang depress anxieti reinforc robust relationship poor sleep qualiti mental health furthermor individu report greater sleep disturb pandem experienc lower relat proport rem deep sleep impact covid pandem univers student multi facet mental health sleep qualiti amount restor sleep negat affect pandem environ compound effect exacerb health consequ pandem highlight need increas attent prevent treatment mental health disord particular vulner popul young adult
|
D000086382;D007319;D012893
|
T184;T047;T067;T048
|
36,301,945
|
contribut tourism mobil tourism econom growth china mobil key factor promot tourism econom growth teg transport infrastructur essenti function maintain order flow tourist base theori fluid mechan put forward indic tourism mobil tm studi first measur level tm china analyz spatiotempor evolut characterist tm appli exploratori spatial data analysi method analyz global local spatial correl characterist tm moreov estim contribut tm teg econometr model lmdi method result show tm china maintain rapid growth long time howev differ rate growth differ region tm region show signific posit spatial correl space time pattern constant chang time local spatial autocorrel result tm stabl various agglomer state stabli distribut provinc regress result tradit panel data model spatial panel data model show tm signific posit effect teg moreov tm negat spatial spillov effect neighbor region result decomposit lmdi show overal contribut tm teg show improv tm crucial way promot econom growth tourism
|
D057217;D000085926
|
T081;T056
|
36,301,944
|
suicid capabl within ideat action framework systemat scope review suicid capabl theoris facilit movement suicid ideat suicid attempt three type contributor posit compris suicid capabl acquir disposit practic despit suicid capabl critic movement ideat attempt systemat synthesi empir evid relat suicid capabl would enabl develop refin concept studi sought address synthesi gap scope review conduct suicid capabl studi publish januari januari eleven electron databas grey literatur sourc search return potenti studi exclus criteria applic studi includ final analysi result synthesi follow textual narrat approach alloc studi base contributor suicid capabl studi focus investig one factor within contributor pain provoc event appear contribut acquir capabl fearless death whilst emerg evid disposit practic contributor promis small number studi prevent conclus drawn unexpect addit cognit contributor identifi focus singl factor studi limit number studi contributor acquir capabl limit theoret develop practic applic suicid capabl knowledg given suicid complex multifacet behaviour futur research incorpor combin contributor like advanc understand suicid capabl
|
D013406;D059020
|
T033;T037;T048
|
36,301,942
|
prefer homebirth associ factor among pregnant women arba minch health demograph surveil site southern ethiopia home birth prefer need pregnant women give birth home help tradit unskil birth attend homebirth unskil birth attend childbirth main lead indic matern newborn death ethiopia number women prefer homebirth assist unskil person howev inform regard problem arba minch zuria woreda therefor import identifi preval prefer homebirth associ factor
|
D006700
|
T033
|
36,301,941
|
develop valid clinic predict model sever critic pediatr covid infect children infect covid suscept sever manifest aim develop valid predict model sever critic pediatr covid infect util routin avail hospit level data ascertain likelihood develop sever manifest
|
D000086382
|
T047;T067
|
36,301,939
|
silico investig quinin quinidin potenti inhibitor akrb akrb function structur character aberr express aldo keto reductas akrb akrb extens studi differ type cancer especi colon cancer studi yet report regard discoveri inhibitor treatment colon cancer target isozym therefor need select inhibitor target erad colon cancer current studi focus explor two quinolon compound ie methoxyquinolin yl srsr vinylquinuclidin yl methanol quinidin r methoxyquinolin yl sssr vinylquinuclidin yl methanol quinin potenti inhibitor akrb akrb via detail silico approach structur properti includ vibrat frequenc dipol moment polariz optim energi estim use densiti function theori dft calcul compound found chemic reactiv optim structur use molecular dock studi quinidin found select toward akrb quinin exhibit maximum inhibit akrb result molecular dock studi valid molecular dynam simul provid deep insight stabil protein ligand complex end admet properti determin demonstr druglik properti select compound find suggest explor compound molecular level use differ vivo vitro approach lead design potenti inhibitor akrbakrb cure colon cancer relat malign
|
D000449;D000074408;D003110;D011802;D011803
|
T121;T123;T116;T109;T191;T126
|
36,301,932
|
communiti structur model vaccin strategi control covid spread mathemat studi initi effort mitig covid pandem reli heavili non pharmaceut intervent npis includ physic distanc hand hygien mask wear howev effect vaccin essenti contain spread virus develop compartment model examin differ vaccin strategi control spread covid framework account test rate test turnaround time vaccin wane immun use report case data citi toronto canada mar dec defin epidem phase infect use contact rate well probabl transmiss upon contact investig impact vaccin distribut compar differ permut wane immun vaccin coverag efficaci throughout various stage npi relax term case death basic reproduct number also studi observ widespread vaccin coverag substanti reduc number case death phase high transmiss earli late reopen result new resurg infect even highest coverag hand phase lower transmiss coverag enough prevent new infect analysi r show basic reproduct number reduc decreas test turnaround time transmiss household found household transmiss decreas follow introduct vaccin public health effort reduc test turnaround time remain import virus contain
|
D000086382;D014612
|
T129;T121;T116;T067;T047
|
36,301,929
|
two site h addit iridium complex featur nonspect tricoordin phosphorus ligand synthesi reactiv ambiphil iridium complex ircl pph l l p n n pyridyl c h featur chelat nontrigon phosphorus triamid ligand report tandem lewi basic ir lewi acid p achiev two site oxid addit phenol give iridaphenoxyphosphoran speci irhcl pph l oph contrast reaction benzenethiol benzeneselenol engag l instead proceed via metal center oxid addit chalcogen hydrogen bond find establish metal ligand cooper involv nonspect reactiv tricoordin phosphorus ligand
|
D007495;D010758
|
T196;T197
|
36,301,926
|
seropreval correl kinet sar cov nucleocapsid igg antibodi healthcar worker nonclin staff tertiari hospit prevaccin census studi healthcar worker nonclin staff medic facil perceiv high risk group acquir sar cov infect countri covid vaccin uptak low serosurveil may best determin true extent sar cov infect sinc infect hcws staff may asymptomat present mild symptom time determin true extent sar cov infect could inform hospit manag staff whether prevent measur institut effect valuabl develop target solut
|
D000086402;D000086382
|
T005;T067;T047
|
36,301,923
|
predict admiss cost follow anterior cervic discectomi fusion util machin learn retrospect case seri
|
D013123
|
T061
|
36,301,922
|
design hierarch porous singl atom fe n catalyt site high oxidas like activ sensit detect organophosphorus pesticid recent singl atom catalyst sac use construct biosensor determin organophosphorus pesticid op howev nanozym includ sac peroxidas like enzym requir high toxic unstabl hydrogen peroxid h co reactant generat reactiv oxygen speci inspir heme site cytochrom c oxidas c c os construct fe n coordin sac introduc axial n ligand expect bind generat activ metal oxygen intermedi herein sac fe n activ center confin hierarch porous carbon nanofram fe sasn pc prepar polymer pyrolysi evapor etch strategi under enzym like mechan uncov experi densiti function theori calcul metal atom util increas access activ site acceler mass transfer excel hydrophil electron driven mechan axial n endow sac enhanc oxidas like activ notabl catalyt rate constant time greater commerci ptc catalyst similar catalyt mechan c c os convert reactiv oxygen speci avoid use co reactant h effect addit base inhibitori effect thiol activ site fe sasn pc biosensor construct appli colorimetr analysi op provid facil cost effect method effici op screen site help control contamin
|
D010088;D010575
|
T131;T126;T116
|
36,301,921
|
cluster icu patient sepsi base pattern circul biomark secondari analysi captain prospect multicent cohort studi although sepsi life threaten condit heterogen present like explain negat result trial adjunct therapi studi patient sepsi aim identifi subgroup similar immun profil clinic outcom correl
|
D018805
|
T047;T046
|
36,301,920
|
acut effect knee extens exercis differ contract durat subsequ maxim knee extens torqu among athlet differ strength level individu high fatigu resist high intens condit activ ca may abl avoid experienc signific fatigu enhanc voluntari perform examin whether optim contract durat dynam knee extens exercis maxim subsequ voluntari perform vari depend strength level individu studi particip male american colleg footbal player initi particip perform maxim isometr knee extens exercis classifi stronger individu n weaker individu n base relat muscl strength group perform three type dynam ca differ contract durat ca ca ca random order observ time cours chang post activ potenti perform enhanc twitch torqu induc electr stimul isokinet knee extens torqu record ca twitch torqu increas min ca stronger individu p howev post activ potenti induc weaker individu either protocol voluntari perform increas min ca stronger individu p howev post activ perform enhanc either protocol weaker individu thus ca relat long contract durat optim maxim subsequ voluntari perform stronger individu remain unknown whether cas perform relat short long contract durat optim weaker individu
|
D007537;D007717
|
T023;T042
|
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