PMID int64 27.8M 36.2M | Title/Abstract stringlengths 7 10.7k | MeshTerms stringlengths 7 104 | SemanticTypes stringlengths 4 84 |
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34,689,468 | sinic cross cultur adjust reliabl valid test burnt hand outcom tool object introduc burnt hand outcom tool bhot china conduct sinic cross cultur debug test reliabl valid thus provid refer evalu treatment effect make medic decis hand burn patient method cross section research conduct obtain author origin author brislin translat mode use liter translat synthes back translat check expert form chines version bhot c bhot ten expert field burn rescu treatment invit purpos sampl method conduct cross cultur debug form c bhot total hand burn patient treat general hospit ningxia medic univers januari march conform inclus criteria select accident sampl method pre test final version c bhot form hospit patient met select criteria recruit use accident sampl multi site cross region survey method may march general hospit ningxia medic univers first affili hospit air forc medic univers first affili hospit armi medic univers third militari medic univers first affili hospit nanchang univers survey perform general inform questionnair c bhot critic ratio method correl coeffici method use item analysi cronbach coeffici test tool use test intern consist test retest reliabl use judg stabil tool content valid index analysi tool use analyz content valid exploratori factor analysi use test valid structur data statist analyz independ sampl test pearson correl analysi result sinic cross cultur debug pre test c bhot form total item item adjust posit score modif made basi origin tool total questionnair issu formal survey valid questionnair return effect respons rate patient male patient patient femal patient patient age year critic ratio item item analysi rang p statist signific differ score patient high score group low score group p p signific posit relationship among score two item score item overal tool score r p p reliabl test cronbach coeffici whole tool test retest reliabl valid test content valid index whole tool exploratori factor analysi extract common factor cumul varianc contribut rate compar fit index confirmatori factor analysi conclus bhot tool sinic cross cultur debug pre test test reliabl valid verifi c bhot good reliabl valid assess outcom chines hand burn patient therefor use effect tool evalu | D003431;D014177 | T062;T170 |
34,689,467 | scope review prevent central venous cathet relat bloodstream infect burn patient object investig research trend scope prevent central venous cathet relat bloodstream infect crbsi burn patient method scope review method adopt pre retriev carri search term central venous cathet infect cathet relat bloodstream infect burn basi pre retriev differ retriev formula formul retriev research relat central venous crbsi burn patient china nation knowledg internet wanfang databas vip databas pubm embas cinahl cochran librari establish databas august data extract includ literatur includ first author research public time research countri research type diagnosi basi intervent measur central venous crbsi research sampl select incid relat infect research conclus result total random control trial quasi experiment studi case control studi cohort studi implement research publish includ studi first author china unit state america argentina diagnost base central venous crbsi burn patient uniform includ literatur includ adopt guidelin american center diseas control prevent diagnost criteria nosocomi infect diagnost criteria without specifi sourc intervent measur includ use new materi antibiot coat cathet ethanol impregn port protector multidisciplinari cooper comprehens prevent measur sampl size includ literatur small sampl select differ includ number patient number placement central venous cathet outcom indic infect includ literatur diversifi incid per day central venous crbsi patient control group china incid per day central venous crbsi most control group foreign countri incid central venous crbsi decreas vari degre implement correspond intervent measur relat research conclus show new materi multidisciplinari cooper comprehens prevent measur good effect prevent central venous crbsi burn patient conclus research prevent central venous crbsi burn patient china start earli research type diversifi diagnost criteria central venous crbsi burn patient uniform intervent measur shift standard relev oper measur explor prevent effect new materi multidisciplinari cooper multipl measur latter good effect prevent central venous crbsi burn patient | D016470;D002056;D055499;D062905;D003428 | T074;T047;T037;T046 |
34,689,466 | experiment studi effect three dimension porous structur vascular rate artifici dermi object explor effect orient three dimension porous network type honeycomb briquett shape vertic penetr three dimension porous network type b vascular rate artifici dermi method experiment research method use artifici dermi compos doubl layer silicon layer scaffold layer base differ scaffold layer divid type type b artifici dermi type dermi type b dermi short contain type type b structur respect type type b structur prepar gradient freez dri techniqu physic pore make techniqu respect micro morpholog two kind dermi scaffold observ scan electron microscopi poros two kind dermi scaffold measur pyrex method accord method nation medic industri standard hydroxyprolin content degrad liquid residu two kind dermi determin degrad h reflect degrad rate two kind dermi accord random number tabl l cell divid type dermi group type b dermi group negat control group posit control group posit control group ad minimum essenti medium mem contain dimethyl sulfoxid negat control group ad high densiti polyethylen extract two group ad correspond extract hour cultur growth rate l cell detect methyl thiazolyl tetrazolium cytotox grade l cell human umbil vein endotheli cell huvec inocul pore plate two kind dermi preinstal inocul adhes growth l cell surfac two kind scaffold detect immunofluoresc method inocul migrat two kind cell two kind dermal scaffold detect immunofluoresc hematoxylin eosin stain three full thick skin defect wound cm cm creat side back three month old healthi male ba mini pig accord random number tabl six column wound divid type dermi two step method group type b dermi two step method group type b dermi one step method group wound type dermi two step method group type b dermi two step method group transplant type type b dermi respect autolog split thick skin graft later wound type b dermi one step method group transplant synchron procedur includ type b dermi without silicon layer autolog skin graft simultan bleed exud infect wound back type dermi two step method group type b dermi two step method group th day second transplant type b dermi one step method group th day first transplant general observ area autolog skin graft measur transpar film grid method surviv rate autolog skin calcul first transplant inflammatori cell fibroblast fbs capillari infiltr scaffold three group detect stain first transplant vascular scaffold observ immunohistochemistri first oper degrad scaffold type dermi type b dermi observ stain data statist analyz one way analysi varianc independ sampl test bonferroni correct result larg number round oval micropor even distribut surfac type scaffold cylindr hole wall could observ arrang parallel direct longitudin section honeycomb briquett shape penetr macropor surfac type b scaffold arrang order matrix pore wall honeycomb briquett shape penetr macropor connect micropor form network structur poros type dermi similar type b dermi p degrad rate type dermi h similar type b dermi correspond time point p h cultur prolifer rate l cell type dermi group type b dermi group negat control group signific higher posit control group p cytotox rate cell posit control group grade three group grade zero inocul l cell huvec prolifer time depend manner two kind dermal scaffold adhes growth prolifer rate two kind cell surfac type b dermi higher type dermi inocul l cell huvec cover surfac type b dermi migrat one side silicon layer howev two kind cell migrat slowli type dermi cell found one side silicon layer bleed exud infect wound repair type type b dermi surviv rate autolog skin graft wound group first oper inflammatori cell fbs capillari gradual infiltr scaffold layer cell infiltr rate high low type b dermi one step method group type b dermi two step method group type dermi two step method group scaffold wound type b dermi one step method group gradual collaps first oper complet degrad month first oper scaffold degrad rate type dermi two step method group similar mention conclus honeycomb briquett shape vertic penetr three dimension porous network structur type b scaffold acceler vascular process benefici autogen split thick skin one step procedur repair full thick skin defect wound ba mini pig compar two step method stage transplant type scaffold autolog split thick skin one step transplant equal efficaci provid better choic wound treatment | D017768;D014945 | T040;T122 |
34,689,465 | applic effect free transplant autolog omentum treat maxillofaci infect complic complex sinus tract object investig applic effect free transplant autolog omentum treat maxillofaci infect complic complex sinus tract method retrospect observ studi method use four patient maxillofaci infect complic complex sinus tract admit depart burn plastic surgeri second affili hospit air forc medic univers juli decemb includ male femal age year preoper facial comput tomographi ct perform patient calcul volum sinus tract oper sinus tract thorough debrid volum tissu defect cm cm cm cm cm cm debrid tissu defect area fill omentum ml cut laparoscopi arteri vein right side omentum reserv vascular pedicl donor area anastomos facial arteri extern jugular vein recipi area surviv omentum occurr reinfect complic observ oper respect th day month oper blood suppli omentum examin color doppler ultrasound ct angiographi fill tissu defect area examin head face ct follow oper recoveri face appear function scar hyperplasia donor area result transplant omentum patient surviv oper reinfect complic th day month oper transplant omentum good blood suppli fill area omentum good shape without format dead caviti follow month surgeri appear function face recov well obvious scar hyperplasia donor area conclus free transplant omentum treat maxillofaci infect complex sinus tract patient good facial appear function applic laparoscopi result littl damag patient quick postop recoveri | D002056;D019651;D017695 | T061;T037 |
34,689,464 | microbiolog characterist patient sever burn caus blast applic meta genom next generat sequenc detect pathogen microorgan object analyz microbiolog characterist patient sever burn caus blast differ period explor applic valu metagenom next generat sequenc mngs detect pathogen microorgan method retrospect observ studi appli june septemb twenti three patient male femal sever burn caus blast met inclus criteria admit second affili hospit zhejiang univers school medicin age year total burn area total bodi surfac area abbrevi burn sever index absi score revis baux score acut physiolog chronic health status evalu apach score sequenti organ failur assess sofa score count admiss within admiss complic infect sourc distribut pathogen microorgan patient record detect pathogen microorgan analyz differ detect effici microbi cultur method mngs compar admiss infect overal sourc distribut pathogen microorgan patient analyz differ detect effici microbi cultur method mngs compar data statist analyz mcnemar fisher exact probabl test result admiss absi score revis baux score apach score sofa score respect within admiss main complic patient inhal injuri septic shock hypoproteinemia patient main infect pathogen microorgan wound blood stream lung within admiss incid septic shock highest incid inhal injuri signific lower admiss p main sourc infect wound lung blood stream incid wound blood stream infect signific lower admiss p within admiss incid multipl organ failur acut respiratori distress syndrom low incid inhal injuri signific lower admiss p incid septic shock signific lower admiss p admiss p low bloodstream infect incid wound infect signific lower admiss p admiss p incid lung blood stream infect signific lower admiss p within admiss gram posit bacteria main staphylococcus aureus gram negat bacteria main klebsiella pneumonia stenotrophomona maltophilia fungi contain candida within admiss staphylococcus aureus main gram posit bacteria detect rate enterococcus signific lower admiss p pseudomona aeruginosa acinetobact baumannii main gram negat bacteria detect rate signific lower admiss p new detect fusarium within admiss staphylococcus aureus main gram posit bacteria detect rate enterococcus bacillus signific lower admiss p pseudomona aeruginosa acinetobact baumannii still main gram negat bacteria increas extens time admiss detect rate pseudomona aeruginosa signific higher admiss p admiss p detect rate acinetobact baumannii signific higher admiss p detect rate klebsiella pneumonia signific lower admiss p admiss p candida mould fusarium detect within consist mngs bacteri cultur high within admiss consist mngs bacteri cultur moder differ time period posit test rate mngs basic constant microbi cultur show declin extens time admiss five hundr six strain pathogen microorgan isol wound blood sputum indwel cathet staphylococcus aureus pseudomona aeruginosa acinetobact baumannii klebsiella pneumonia main pathogen microorgan pseudomona aeruginosa acinetobact baumannii common wound sampl klebsiella pneumonia often seen blood sampl pseudomona aeruginosa acinetobact baumannii sputum sampl acinetobact baumannii indwel cathet sampl common detect rate pseudomona aeruginosa wound sputum signific higher blood p p indwel cathet p respect consist overal result mngs microbi cultur moder consist mngs microbi cultur high sampl blood indwel cathet moder sputum wound conclus common infect patient sever burn caus blast injuri wound infect blood stream infect extens time admiss main pathogen bacteri strain patient chang staphylococcus aureus klebsiella pneumonia stenotrophomona maltophilia acinetobact baumannii pseudomona aeruginosa mngs show higher posit rate detect pathogen microorgan convent microbi cultur | D000900;D002056 | T195;T121;T037 |
34,689,463 | effect mechan age stiff fibrot phenotyp fibroblast human hypertroph scar object explor effect potenti molecular mechan age stiff fibrot phenotyp fibroblast fbs human hypertroph scar method experiment research method use januari june surgic remov hypertroph scar tissu scar patient male femal residu full thick normal skin tissu case male femal age year collect oper depart burn plastic surgeri fourth medic center pla general hospit hypertroph scar tissu patient age year includ young group hypertroph scar tissu patient age year includ elder group accord age patient normal skin tissu scar tissu two group hematoxylin eosin stain perform observ tissu morpholog masson stain perform observ morpholog arrang collagen quantifi content collagen scan electron microscop use observ microscop differ dermal collagen fiber sampl freez dri metal coat stiff scar tissu two group measur atom forc microscop liquid phase scar tissu two group collect fbs isol cultur morpholog differ fbs observ invert phase contrast microscop protein express paxillin detect cellular immunofluoresc reflect morpholog fbs cellular immunofluoresc use detect express pro fibrosi protein smooth actin sma transform growth factor tgf type collagen mechanotransduct relat protein yes associ protein yap prolifer relat protein ki real time fluoresc quantit revers transcript polymeras chain reaction use detect mrna express pro fibrosi gene tgf sma type collagen fibrosi inhibit gene tgf mechanotransduct relat gene rho associ protein rock yap data statist analyz one way analysi varianc least signific differ test result stain show epiderm layer normal skin uneven blood vessel sweat gland could seen dermal layer epiderm layer scar tissu two group relat flat blood vessel sweat gland rare masson stain scan electron microscopi show collagen fiber normal skin arrang loos disord collagen fiber scar tissu two group arrang dens order collagen fiber scar tissu young group denser elder group collagen content scar tissu young group elder group signific higher normal skin tissu p p collagen content scar tissu elder group signific lower young group p dermal stiff scar tissu elder group kpa signific higher kpa young group p obvious differ morpholog scar fbs two group observ invert phase contrast microscop cellular immunofluoresc express type collagen tgf scar fbs cytoplasm elder group signific higher young group express sma scar fbs cytoplasm close two group express yap cytoplasm nucleus scar fbs elder group signific higher young group express ki scar fbs nucleus two group close mrna express tgf type collagen scar fbs elder group signific higher young group p p mrna express tgf scar fbs elder group signific lower young group p mrna express rock yap scar fbs elder group signific higher young group p p conclus elder prone scar heal skin injuri molecular mechan may attribut product extracellular matrix compon higher stiff increas tissu stiff therebi activ express rock yap transcript co activ pdz bind motif gene promot pro fibrosi gene protein express | D017439 | T020 |
34,689,462 | fluid resuscit strategi efficaci evalu shock stage sever burn children differ burn area differ age group object explor fluid resuscit strategi shock stage sever burn children differ burn area differ age group evalu curat effect method retrospect cohort studi conduct januari june children sever burn met inclus criteria hospit first affili hospit nanchang univers includ male femal age month year admiss plan rehydr children electrolyt colloid water accord domest rehydr formula pediatr burn shock rehydr volum speed adjust accord children mental state peripher circul heart rate blood pressur urin output etc actual input volum plan input volum electrolyt colloid water total fluid children record hour sinc fluid replac first second hour injuri accord urin output hour sinc fluid replac children divid satisfactori urin output mainten group case urin output mlkg h unsatisfactori urin output mainten group case urin output mlkg h electrolyt coeffici colloid coeffici water coeffici children calcul hour sinc fluid replac accord total burn area children age tbsa group respect electrolyt coeffici colloid coeffici water coeffici urin output children calcul count first second hour injuri non invas monitor indic bodi temperatur heart rate respiratori rate percutan arteri oxygen satur efficaci indic hematocrit platelet count hemoglobin albumin creatinin alanin aminotransferas alt children record hour injuri prognosi outcom indic children treatment count includ complic cure improv discharg automat discharg death data statist analyz independ sampl pair sampl test mann whitney u test chi squar test fisher exact probabl test result hour sinc fluid replac actual input volum electrolyt children signific plan input volum actual input volum colloid water total fluid signific less plan input volum z p first second hour injuri actual input volum electrolyt children signific plan input volum actual input volum water total fluid signific less plan input volum z p water coeffici signific increas z p among children tbsa group electrolyt coeffici water coeffici children signific increas urin output children signific decreas tbsa group first second hour injuri z p p level efficaci indic hematocrit platelet count hemoglobin h injuri signific increas alt level signific decreas z p p tbsa group electrolyt coeffici water coeffici children tbsa group signific increas first second hour injuri colloid coeffici second h signific decreas z p p complic occur children treatment among children case cure account case improv discharg account case discharg automat account case die account conclus electrolyt volum earli fluid resuscit sever burn children exceed volum calcul formula obtain good therapeut effect among children year old volum fluid resuscit appropri increas children extrem sever burn compar children sever burn fluid resuscit among children age year colloid volum appropri increas children extrem sever burn compar children sever burn fluid resuscit non invas monitor indic use monitor hemodynam guid fluid resuscit sever burn children | D002056;D012769 | T046;T037 |
34,689,461 | role first aid network construct earli treatment patient critic sever hydrofluor acid burn object explor role first aid network construct earli treatment patient critic sever hydrofluor acid burn method twenti seven fluorin chemic enterpris distribut zhejiang provinc jiangxi provinc fujian provinc inner mongolia autonom region hospit burnplast depart profession burn treatment group zhejiang provinc includ zhejiang quhua hospit hospit outsid zhejiang provinc involv first aid network construct member unit main unit zhejiang quhua hospit respons daili mainten technic guidanc first aid network zhejiang quhua hospit assign design emerg hospit fluorin chemic enterpris near emerg hospit fluorin chemic enterpris assign design hospit medic record patient male critic sever hydrofluor acid burn admit first aid network hospit januari june meet inclus criteria involv retrospect cohort studi base whether enterpris belong first aid network construct patient divid first aid network group case age year non first aid network group case age year patient first aid network group injur enterpris hospit link immedi hospit patient treat mobil treatment forc equip materi drug advanc first aid network therebi realiz seamless joint pre hospit first aid hospit treatment hospit start first aid process temporarili mobil rescu forc equip materi drug patient non first aid network group arriv depart emerg hospit time injuri medic servic first detect time serum calcium time stay depart emerg durat hypocalcemia hypomagnesemia treatment outcom patient two group record data statist analyz chi squar test fisher exact probabl test independ sampl test wilcoxon rank sum test result time injuri medic servic first detect time serum calcium time stay depart emerg patient first aid network group min signific shorter min non first aid network group z p p durat hypocalcemia hypo magnesemia patient first aid network group h signific shorter h non first aid network group z p conclus critic sever hydrofluor acid burn extrem urgent situat encount clinic practic construct first aid network creat condit site treatment patient improv first aid effici therebi gain time save live | D002056;D006996 | T047;T037 |
34,689,460 | clinic applic extracorpor membran oxygen treatment burn patient acut respiratori distress syndrom retrospect analysi systemat review object analyz clinic effect extracorpor membran oxygen ecmo treatment burn patient acut respiratori distress syndrom ard method retrospect observ studi systemat review appli march juli five burn patient ard receiv ecmo treatment first affili hospit armi medic univers third militari medic univers five patient male age year averag total burn surfac area total bodi surfac area tbsa four case sever inhal injuri patient ecmo start time durat mode whether success wean caus death other record furthermor chang oxygen infect util ecmo analyz pubm web scienc establish databas august search use extracorpor membran oxygen ecmo burn inhal search term titleabstract field retriev clinic articl meet select criteria basic inform extract articl includ sampl size gender age total burn area inhal injuri indic ecmo start last time ecmo ecmo mode rate success wean complic ecmo mortal combin applic continu renal replac therapi crrt result five patient start venoven ecmo averag day injuri last averag hour three patient wean success one patient surviv four patient die multipl organ dysfunct syndrom mod septic shock compar ecmo treatment arteri oxygen partial pressur pao oxygen satur arteri blood sao three success wean patient obvious increas ecmo treatment fraction inspir oxygen fio decreas pao fio ratio increas mmhg mmhg kpa ecmo furthermor lactic acid respiratori rate decreas basic compar ecmo pao sao two patient ecmo fail wean continu decreas lactic acid increas ecmo pao fio ratio unsuccessfullg wean case less mmhg partial pressur carbon dioxid arteri blood paco mmhg compar ecmo signific chang bodi temperatur ecmo less compar ecmo leucocyt number index without unsuccess wean case omit four patient show signific decreas ecmo rose remov ecmo proport neutrophil three patient slight higher ecmo ecmo chang signific remov ecmo compar ecmo platelet count three patient signific reduc ecmo five patient ecmo normal level compar ecmo procalcitonin level four death signific increas ecmo cathet cultur microorgan perform three success wean patient negat total literatur includ rang sampl size studi less sampl size studi literatur sampl size larger ecmo appli burn patient overal mortal includ adult children common indic ecmo sever ard among adult burn patient male femal case inhal injuri averag burn area tbsa report studi tbsa report studi common mode venoven ecmo ecmo treatment began hour day injuri last hour day rate success wean rang common complic bleed infect mortal mod sepsi lead caus death among pediatr burn patient boy girl patient inhal injuri averag burn area tbsa studi ecmo treatment last hour hour bleed common complic mortal conclus ecmo effect strategi salvag treatment burn complic ard furthermor prevent treatment bleed infect organ dysfunct emphas use ecmo import evid base guidelin burn urgent need improv clinic effect ecmo | D002056;D015199;D012128 | T061;T047;T037 |
34,689,459 | past present futur critic burn treatment fatal rate patient critic burn extrem high clinic treatment challeng review histori treatment critic ill burn patient articl elabor analyz advanc concept technolog home abroad critic burn treatment area includ shock fluid resuscit hypermetabol nutrit inhal injuri respiratori support acut kidney injuri continu renal replac therapi wound assess manag infect control coagulopathi prevent treatment etc furthermor thought futur develop trend critic burn treatment put forward refer peopl field | D002056;D012769 | T046;T037 |
34,689,455 | impact medic scribe emerg physician diagnost test diagnosi chart sinc widespread adopt electron medic record emr medic scribe increas util emerg depart ed set offload document burden emerg physician ep scribe shown increas ep product satisfact howev littl known effect ep diagnost process aim assess effect scribe ep diagnost test order document differenti diagnos | D017060;D010820 | T097;T080 |
34,689,454 | effect ion releas filler contain gel applic dentin reminer use optic coher tomographi examin effect ion releas filler contain gel reminer dentin use optic coher tomographi oct | D017001 | T047 |
34,689,453 | offic bleach complet cervic third protect protocol split mouth doubl blind random clinic trial evalu bleach sensit bleach effect offic bleach follow protocol complet cervic third protect gingiv dam comparison tradit manner appli gingiv dam use gingiv sulcus area | D003807;D014073;D058205 | T167;T047;T061 |
34,689,452 | effect ppm sodium fluorid polish dentin citric acid eros use chang step height measur step height chang use profilometri dentin pre treatment sodium fluorid ppm eros citric acid | D012969;D014077 | T047;T121;T197 |
34,689,451 | carica papaya mouthrins inhibitor streptococcus mutan random control clinic trial evalu effect carica papaya mouthrins inhibitor streptococcus mutan | D029441;D013295 | T007;T002;T168 |
34,689,450 | evalu adipokin level obes women periodont cohort studi evalu inflamm relat adipokin level bodi fluid obes femal particip without periodont use healthi particip control group | D054392;D055113 | T116;T047;T123 |
34,689,449 | influenc fatigu load various adhes resin lute agent zirconia reinforc lithium silic ceram bond dentin examin fatigu failur load valu etch rins self adhes lute system use bond zls dentin moreov studi seek evalu whether applic unfil resin silan ceram intaglio surfac could improv fatigu failur load valu | D001840;D019279 | T122;T061 |
34,689,448 | associ track oral hygien dental outcomesin general dental practic track plaqu score subset teeth general dental practic patient determin plaqu score could improv along periodont restor extract outcom | D003773;D010518 | T047 |
34,689,447 | effect polish system storag media color stabil surfac rough bulk fill restor composit determin effect polish system storag media surfac rough color chang four bulk fill restor composit | D003188;D003775 | T122;T061 |
34,689,446 | low torqu risk factor non carious cervic lesion nccls maxillari premolar determin preval non carious cervic lesion nccls maxillari premolar differ torqu simul cervic stress profil premolar coincid load use finit element analysi fea | D019237 | T023 |
34,689,445 | stain whiten product induc color chang resin composit evalu color gloss chang three differ resin composit stain whiten | D003069;D014867 | T121;T168;T197 |
34,689,444 | micro comput tomographi analysi abras toothpast tablet compar convent toothpast evalu microct dentin enamel abras depth caus toothpast tablet compar convent toothpast | D014072;D014100 | T046;T122 |
34,689,443 | object determin peripher edema heart failur patient use short wave infrar molecular chemic imag peripher pit edema clinician administ measur grade edema peripher edema grade subject major limit techniqu pilot clinic studi short wave infrar swir molecular chemic imag mci effect object non contact quantit peripher edema measur underway | D006333;D057054 | T047;T060;T046 |
34,689,442 | classif imbalanc oral cancer imag data high risk popul earli detect oral cancer vital high risk patient machin learn base automat classif ideal diseas screen howev current dataset collect high risk popul unbalanc often detriment effect perform classif | D009062;D016571 | T191;T170 |
34,689,441 | challeng healthi age diabet isra nation diabet council guidelin treat older peopl preval diabet increas age diabet risk factor mani complic cardiovascular diseas kidney failur stroke neuropathi retinopathi data recent year indic also risk factor cognit impair dementia function disabl frailti diabet diseas requir complex self care capabl individu diabet requir take medic time examin feet exercis maintain balanc diet preform daili glucos monitor cope hypoglycemia understand differ life situat may effect glucos level requir intact cognit function abil thus treatment plan take consider person cognitivefunct state inde last sever year mani profession organ american diabet associ intern diabet feder american endocrinolog societi publish guidelin treat older peopl diabet isra nation diabet council head prof itamar raz collabor physician union nation council recent author isra guidelin treat older peopl diabet isra guidelin includ categor older adult diabet relat function status order reach determin treatment target accord isra guidelin accord intern guidelin treatment target elder person diabet determin chronolog age individu rather risk function deterior older peopl diabet categor three group accord risk function deterior categori uniqu glucos blood pressur lipid target guidelin offer valid reliabl tool addit person acquaint patient help determin level risk function declin | D003920;D000073656;D007003 | T047;T102 |
34,689,440 | nation diabet program israel select countri current state futur trend israel nation program diabet prevent care establish endors minist health ultim goal program ensur peopl diabet high risk develop diabet live well access high qualiti servic meet individu need aim paper describ program scope main compon foremost achiev addit review nation program select countri worldwid highlight current futur trend affect diabet manag care | D003920 | T047 |
34,689,439 | diabet foot israel current status futur perspect diabet foot ulcer amput dread diabet complic annual incid diabet foot ulcer israel estim patient diabet number patient diabet undergo major amput recent decad relat stabl israel patient diabet undergon major amput proport patient undergo vascular intervent year prior major amput remain steadi recent decad rang depend patient age aim reduc amput rate effort made three level primari care increas awar patient health care team diabet foot complic mean avoid deliveri preliminari care effort increas awar undertaken identif foot risk incorpor profession team care patient well provis appropri prevent offload footwear sought secondari clinic multidisciplinari clinic tend complic adequ address primari care profession standard clinic determin access clinic improv adequ equip clinic mandatori well tertiari hospit care patient requir hospit nation standard inpati diabet foot care implement multi disciplinari depart incorpor internist orthopedist vascular surgeon establish aim address medic surgic complex patient qualifi nurs staff well addit health care profession includ physiotherapist dietician clinic pharmacist social worker occup therapist other also includ document diabet foot ulcer lack communiti hospit use uniform diagnost code implement enabl close monitor diseas trend | D003920;D017719 | T047 |
34,689,438 | improv renal outcom sodium glucos cotransport sglt inhibitor publish empa reg cardiovascular outcom trial cvot investig empagliflozin patient type diabet td agent promot glycosuria inhibit sodium glucos cotransport sglt express first segment renal proxim tubul studi aim provid evid drug cardiovascular cv safeti requir regulatori author newli develop glucos lower agent gla surpris besid safe empagliflozin effect reduc cv morbid mortal well improv renal outcom compar placebo empa reg follow subsequ cvot demonstr valu addit sglt inhibitor improv cv renal outcom differ popul patient most normal kidney function declar timi earli stage chronic kidney diseas ckd empa reg canva patient advanc proteinur ckd credenc intrigu recent report demonstr sglt inhibitor improv cv renal outcom high risk popul without td patient ckd dapa ckd heart failur reduc eject fraction hfref dapa hf emperor reduc review focus renal aspect larg trial investig sglt inhibitor discuss popul investig defin renal outcom hierarchi within trial use framework interpret renal find conclus last outlin suggest mechan under renal protect effect inhibitor sglt | D003924;D006333 | T047;T046 |
34,689,437 | inclus risk diabet foot hospit discharg letter order enhanc prevent measur communiti sever foot ulcer diabet patient call diabet foot one debilit complic diabet mellitus result huge cost person public best way avoid complic identifi risk factor diabet foot take earli prevent action given time hospit patient diabet whether depart intern medicin other everi diabet patient hospit depart intern surgeri geriatr rehabilit psychiatr undergo evalu determin risk level diabet foot nurs staff requir israel ministri health approxim hospit diabet classifi high risk complic diabet foot evalu constitut window opportun intervent order improv patient condit current status evalu appear patient discharg form neither nurs recommend physician instruct case evalu practic valu without vital inform communiti care doctor awar risk therefor take action prevent develop sever complic recent project assess department qualiti success show abl increas amount hospit discharg form contain evalu risk diabet foot dramat intend continu implement process examin respons within communiti order assur recommend continu appear discharg form | D003920;D017719 | T047 |
34,689,436 | comparison recommend desir hbac valu intern ward physician diabet physician applic diabet patient discharg hospit intern ward present studi demonstr clinic signific differ recommend various factor examin determin desir hbac goal diabet patient discharg intern ward | D003924;D010351 | T058;T047 |
34,689,435 | immun checkpoint inhibitor induc diabet mellitus immun checkpoint inhibitor ici transform care cancer patient provid therapeut option advanc malign consid otherwis untreat howev agent associ immun relat advers event ira ici induc diabet ici dm rare complic program death pd program death ligand pd l inhibitor therapi life threaten patient often present sever hyperglycemia diabet ketoacidosi describ two patient rapid onset diabet mellitus associ anti pd therapi follow depth review literatur discuss clinic present potenti mechan optim manag patient ici dm ici use continu expand across wide varieti malign clinician must awar potenti life threaten ira prevent signific morbid mortal | D003920;D000082082;D009369 | T191;T047;T121;T043;T129 |
34,689,434 | hospit due acut diabet foot annual trend predictor morbid mortal year experi multidisciplinari unit sinc patient present hospit acut diabet foot hospit dedic unit studi describ patient characterist trend amput procedur mortal year | D003920;D017719 | T047 |
34,689,433 | hemoglobin ac mortal covid peopl diabet mellitus increas risk develop sever diseas death contract coronavirus diseas covid effect pre covid infect glycem control diseas outcom still unclear previous studi publish leumit health servic lhs includ patient diabet pre covid infect hbac associ need hospit diseas current studi present clinic characterist patient die covid lhs demonstr signific link pre infect hbac | D000086382 | T047;T067 |
34,689,432 | infodemiolog diabet covid pandem analysi discours social media onlin forum cope covid well measur taken prevent spread pose mani challeng peopl diabet seek inform support web understand issu need express onlin discuss valuabl improv support provid time crisi | D000086382;D003920;D061108 | T047;T170;T067 |
34,689,431 | diabet present futur diabet becom largest epidem st centuri near million peopl diagnos diabet similar number peopl pre diabet diabet remain lead caus blind end stage renal diseas amput heart failur israel approxim popul age diabet last year prevent treatment diabet vast improv mortal decreas nonetheless microvascular macrovascular complic remain burden larg proport patient diabet | D003920;D003924;D007676 | T047 |
34,689,430 | robot assist pancreatoduodenectomi consecut case annual trend analysi propens score match comparison periop long term oncolog outcom open method previous report periop oncolog outcom robot assist pancreatoduodenectomi rapd howev follow period rapd relat short diseas match surviv analys lack therefor studi investig time trend periop long term diseas match outcom rapd | D010535;D065287;D012371 | T090;T061;T060 |
34,689,428 | clinic characterist pancreat biliari tract cancer associ lynch syndrom pancreat biliari tract cancer one lynch syndrom associ malign report describ patient background clinic characterist | D001650;D001661;D003123;D010190 | T191;T047 |
34,689,427 | nasal mold prevent relaps nasal deform primari rhinoplasti patient unilater complet cleft lip outcom base compar studi palat plate alon versus nasoalveolar mold recent year mani studi report presurg nasoalveolar mold method improv nose morpholog howev reason effect surgeri never understood evalu effect nasoalveolar mold compar passiv orthoped method without nasal stent focus nostril morpholog primari cheiloplasti use various measur method analyz essenti factor | D002971;D002972;D012225 | T019;T061 |
34,689,425 | ultrastructur observ filtrat membran cell free concentr ascit reinfus therapi malign ascit cell free concentr ascit reinfus therapi cart use treatment diuret resist ascit increas circuit pressur clog filtrat membran often occur cart malign ascit | D001201;D010534 | T191;T047 |
34,689,424 | chromosom scale genom assembl castanopsi tibetana provid power compar framework studi evolut adapt fagacea tree fagacea speci increas use model elucid process mechan adapt speciat integr ecolog evolut genom genus castanopsi belong famili fagacea main distribut across subtrop tropic asia present studi report first chromosom scale genom assembl castanopsi tibetana common speci evergreen broadleav forest subtrop china combin nanopor sequenc hi c technolog enabl high qualiti genom assembl final assembl genom size c tibetana mb estim genom size consist contig n length mb benchmark univers singl copi orthologu busco assess indic complet hi c scaffold generat pseudochromosom repres assembl genom subsequ protein code gene predict function annot mb repetit sequenc genom identifi percentag genom cover te element compar genom analysi reveal c tibetana close relat castanea mollissima diverg c tibetana undergon consider gene famili expans contract evid posit select detect gene show differ arrang pattern compar quercus robur chromosom scale genom assembl c tibetana expand fagacea genom resourc across famili provid power compar framework studi adapt evolut fagacea tree | D029962;D014197 | T002 |
34,689,422 | soil initi bacteri divers nutrient avail determin rate xenobiot biodegrad understand relat import soil microbi divers plant nutrient manag crucial implement effect bioremedi approach xenobiot contamin soil date knowledg interact effect soil microbiom plant nutrient suppli influenc biodegrad potenti soil remain limit studi evalu individu interact effect soil initi bacteri divers nutrient amend organ inorgan plant presenc biodegrad rate pyren polycycl aromat hydrocarbon initi bacteri divers strong posit impact soil biodegrad potenti soil harbour higher bacteri divers show time higher degrad rate soil lower bacteri divers organ inorgan nutrient amend consist improv degrad rate lower divers soil negat inorgan neutral organ effect higher divers soil interest plant presencetyp show signific effect degrad rate treatment structur equat model demonstr initi bacteri divers promin role drive pyren biodegrad rate provid novel evid suggest soil initi microbi divers nutrient amend explicit consid design employ bioremedi manag strategi restor natur habitat disturb organ pollut | D064307;D011084;D012989 | T109;T001;T131;T032;T028 |
34,689,421 | intracellular imag metmyoglobin oxygen use new dual purpos probe eyfp myoglobin mcherri biolog relev nitric oxid reactiv oxygen speci ros signal metabol regul diseas treatment becom abund clear dramat chang noro process accompani chang oxygen landscap call new imag tool provid cellular detail product reactiv speci myoglobin oxid met state noro known sensor absorb chang visibl rang previous employ frster reson energi transfer read deoxygenationoxygen myoglobin creat subcellular sensor myoglobin mcherri add fluoresc protein eyfp sensor creat novel probe sens met format proxi rosno exposur sinc protein present construct also reliev user need measur fluoresc lifetim make sens avail wider group laboratori | D008786;D009211 | T116;T123 |
34,689,419 | rethink uncertainti african swine fever virus contamin feed ingredi risk introduct unit state econom relev pathogen african swine fever virus asfv shown surviv experiment inocul feed ingredi environment condit transocean transport model howev model character likelihood virus surviv various time temperatur process feed ingredi undergo ad swine diet develop quantit risk assess model estim probabl one corn soybean meal ocean vessel tonn contamin asfv would import unit state annual final probabl estim condit base five likelihood probabl initi asfv contamin p asfv inactiv process p transport p recontamin pr asfv inactiv await custom clearanc unit state entri p probabl asfv inactiv model use corn soybean extrud solvent extract process condit time temperatur valu time reduc log estim studi asfv thermal inactiv pork serum p surviv feed ingredi transocean transport p p scenario use determinist valu p pr use explor impact risk model estim complet inactiv asfv extrus solvent extract process regardless initi asfv contamin probabl assum valu recontamin rang high influenti risk one asfv contamin soybean meal vessel enter unit state median risk estim rang probabl interv pi assum pr pi assum pr mean least one vessel asfv contamin soybean meal would import everi year respect raw corn assum contamin p recontamin assum occur pr median probabl one vessel asfv contamin corn enter unit state pi everi year valu recontamin substanti chang risk corn day transport virus surviv transport valu number vessel ship paramet influenti increas likelihood vessel asfv contamin soybean meal corn enter unit state model help identifi knowledg gap influenti output valu serv framework could updat parameter new scientif inform becom avail propos quantit risk assess model develop studi use framework estim risk asfv entri unit state asfv free countri type import feed ingredi may potenti becom contamin ultim model use develop risk mitig strategi critic control point inactiv asfv feed ingredi process storag transport contribut design implement biosecur measur prevent introduct asfv unit state asfv free countri | D000357;D000358;D000821;D005506 | T047;T168;T005;T068;T067 |
34,689,418 | process mother children special healthcar need evolv connect communiti mother children special healthcar need often face mani extra difficulti isol communiti studi conduct sanin region japan decemb februari aim clarifi mother establish adapt connect within communiti qualit descript design studi particip mother care children special healthcar need verbatim data adapt life hospit discharg collect interview analyz modifi ground theori approach data generat concept group four categori follow difficulti life aris care children social isol gain object view current situat futur care children special healthcar need collabor base understand relationship other feel fulfil life describ four phase mother went similar stage transit theori provid support via collabor partnership may effect mother experienc anxieti transit stage | D003695;D009035 | T058;T092;T093;T099 |
34,689,417 | singl nucleotid mutat exon produc novel hla drb null allel hla drb n nucleotid mutat codon hla drb result novel allel hla drb n | D009711 | T114 |
34,689,415 | compar long term outcom laparoscop hepatectomi radiofrequ ablat hepatocellular carcinoma locat anterolater segment liver laparoscop liver resect llr consid standard surgic approach resect small hepatocellular carcinoma hcc locat anterolater segment liver howev studi compar llr radiofrequ ablat rfa case | D006528;D017115;D010535;D008113;D000078703 | T191;T060;T061 |
34,689,414 | character novel hla allel two next generat sequenc method novel hla allel character use two next generat sequenc technolog | D015234;D059014 | T129;T059;T063 |
34,689,413 | extracellular vesicl product gram posit bacteria highlight articl extracellular vesicl format lactococcus lacti stimul prophag encod holin lysin system yue liu eddi smid tjakko abe | D000067128;D013294 | T026;T007 |
34,689,412 | metabol engin saccharomyc cerevisia hydroxytyrosol overproduct direct glucos hydroxytyrosol ht one power dietari antioxid numer applic differ area includ cosmet nutraceut food present work heterolog hydroxylas complex hpabc escherichia coli integr saccharomyc cerevisia genom multipl copi ht product increas redirect metabol flux toward tyrosol synthesi avoid exogen tyrosol tyrosin supplement evalu potenti select strain ht produc glucos adjust medium composit ht product combin select modif engin strain combin cultur condit optim result titr approxim mg l ht obtain shake flask ferment use minim synthet defin medium g l glucos sole carbon sourc best knowledg highest ht concentr produc engin cerevisia strain | D060847;D012441 | T004;T063 |
34,689,411 | prolong disturb proteostasi induc cellular senesc via tempor mitochondri dysfunct subsequ mitochondri accumul human fibroblast proteolyt activ declin age result accumul aggreg protein age organ investig disturb proteostasi caus cellular senesc develop stress induc prematur senesc sip model normal human fibroblast mrc cell treat proteasom inhibitor mg vacuolar type atpas inhibitor bafilomycin bafa day time cours studi reveal signific increas intracellular reactiv oxygen speci ros mitochondri superoxid drug treatment mitochondri membran potenti initi decreas suggest tempor mitochondri dysfunct drug treatment restor along mitochondri accumul drug treatment amp activ protein kinas alpha notabl activ treatment thereaft intracellular atp level signific increas sip induct mg bafa partial attenu co treatment vitamin e rapamycin level ros mitochondri accumul protein aggreg suppress impli critic involv oxid stress mitochondri function sip progress rapamycin co treatment also augment express hsp activ akt could recov proteostasi promot cell surviv respect studi propos possibl pathway disturb proteostasi cellular senesc via excess ros product well function quantit chang mitochondria | D016922;D000074702 | T043;T044 |
34,689,410 | feb journal hidden gem everi quarter feb journal present hidden gem origin research review type articl provid signific advanc discuss recent develop molecular cellular life scienc articl high valu scientif communiti like take opportun promot contribut previous issu journal feel scientif content merit boost exposur | D001690;D011643 | T057;T090 |
34,689,409 | effect high dose spinal cord stimul non surgic intract lumbar radiculopathi hiden studi spinal cord stimul scs increas use non surgic intract low back pain studi design evalu efficaci high dose hd scs util sub percept stimul higher frequenc puls width non surgic predomin low back pain popul month | D059350;D011843;D062187 | T061;T047;T184;T037 |
34,689,407 | genet delet platelet par result reduc thrombosi impair hemostat plug stabil proteas activ receptor par express wide varieti cell includ megakaryocytesplatelet immun cell cardiomyocyt lung epitheli cell function thrombin receptor murin platelet global defici par associ impair hemostasi reduc thrombosi | D006490;D013927 | T046;T121 |
34,689,406 | lactiplantibacillus plantarum hg attenu ii type collagen induc rheumatoid arthriti rat via anti inflammatori inhibit apoptosi studi aim explor therapeut effect lactiplantibacillus plantarum hg hg collagen induc arthriti cia rat mechan | D017209;D001172;D007596;D048191;D019936 | T116;T047;T007;T123;T043;T030 |
34,689,405 | intraspecif interspecif extracellular metabolit remodel biofilm form thermophil spoilag bacteria thermophil spoilag bacteria biofilm form milk powder process pose threat safeti qualiti dairi product research aim understand bacteri behaviour social model biofilm | D005840;D008892 | T121;T109;T130;T168;T031 |
34,689,404 | synthesi antibacteri evalu safeti assess cus nps pectobacterium carotovorum subsp carotovorum copper agent wide use crop protect uniqu mechan resist pathogen bacteria howev applic bring environment pollut biosafeti problem therefor environment friend copper agent attract attent studi copper sulfid nanoparticl cus nps prepar character analyz antibacteri activ safeti | D003300;D044043 | T007;T121;T196;T123 |
34,689,403 | structur character thermal unfold pathway human vegfr domain fold stabil crucial featur protein evolut essenti protein function thus comprehens protein fold mechan repres import complement protein structur function crucial determin structur basi protein misfold context thermal unfold studi repres use tool get molecular descript conform transit govern foldingunfold equilibrium given protein report thermal foldingunfold pathway vegfrd member immunoglobulin superfamili mean high resolut thermodynam approach combin differenti scan calorimetri atom level unfold monitor nmr show vegfrd fold driven oxid induc disulfid pair key event achiev function structur format small hydrophob core surround disulfid bridg fold nucleus induc cooper transit proper fold conform support hypothesi disulfid bond act fold nucleus eas fold process | D017510;D011506 | T044;T116;T123 |
34,689,400 | detect virul extend spectrum lactamas gene salmonella multiplex high resolut melt curv real time pcr assay develop standard multiplex high resolut melt curv hrm real time pcr assay simultan detect salmonella virul extend spectrum lactamas esbl gene food | D012475;D001618 | T007;T116;T126 |
34,689,399 | invis bleed live experi barrier care men hemophilia guidelin world feder hemophilia support provis equit optim care peopl hemophilia pwh howev limit research exist examin live experi pwh barrier care may encount primari object exploratori studi describ experi men hemophilia canada | D006467;D002836 | T047 |
34,689,398 | concept analysi role ambigu experienc hospit nurs provid bedsid nurs care concept role ambigu despit wide applic nurs research lack clear definit conceptu result inconsist defin operation appli research purpos paper analyz defin concept role ambigu among hospit nurs provid nurs care use concept analysi method develop walker avant three defin attribut role ambigu lack inform inform defici lack clariti unpredict anteced includ lack clear role definit lack educationtrain communic problem supervisori behavior support organiz cultur practic environ condit experi group cohes prefer work set consequ role ambigu includ increas stress lack organiz commit job dissatisfact burnout increas intent leav concept analysi provid clear conceptu definit better understand role ambigu among hospit nurs along implic nurs leader educ clinician research support nurs guid futur research paper emphas import nurs manag relationship reduc experi role ambigu among hospit nurs | D002055;D009732 | T058;T048 |
34,689,397 | combin two bacillus strain suppress meloidogyn incognita fungal pathogen enhanc plant growth combin biocontrol agent desir strategi improv control efficaci root knot nematod rkn meloidogyn incognita field condit howev strain compat general test vitro incompat combin normal examin experi planta therefor virtual inform perform incompat strain studi evalu two bacillus strain previous describ incompat vitro effect plant growth suppress incognita pathogen fungi nematophag fungi | D001203;D001407;D018551;D014431;D055549 | T007;T002;T109;T004;T168;T204 |
34,689,396 | robot singl port myomectomi use da vinci sp surgic system pilot studi report initi experi robot singl port myomectomi rspm use da vinci sp surgic system evalu feasibl procedur | D010535;D007889;D065287;D063186;D014594 | T061;T191;T060 |
34,689,395 | understand corallin algal respons ocean acidif meta analysi synthesi ocean acidif oa major threat persist biogen reef throughout world ocean corallin alga compris high magnesium calcit long consid one suscept taxa negat impact oa summar impact explor caus variabl corallin algal respons use reviewqualit assess relev literatur meta analysi quantit assess critic respons discuss physiolog mechan direct futur research find corallin alga experienc reduc abund calcif rate recruit rate declin ph within site calcif laboratori experi simul oa natur elev co site consist physiolog respons corallin alga simul oa eg photo physiolog mineralog surviv calcificationgrowth frequent measur paramet corallin algal oa research meta analys reveal greater declin seawat ph associ signific decreas calcif adult similar nonsignific trend juvenil adult famili mesophyllumacea also tend robust oa though insuffici data test similar trend juvenil oa domin driver major laboratori experi local global driver assess interact oa singl driver often addit though factor chang ph surfac corallin alga light water motion epiphyt act antagonist synergist oa driver advanc experiment design methodolog techniqu understand physiolog corallin algal calcif larg dictat respons oa howev signific challeng still remain includ improv geograph life histori spread research effort need holist assess physiolog | D000461;D012623 | T167;T002 |
34,689,394 | ring finger protein topor modul express tumor suppressor smar colorect cancer via tlr trif pathway top bind arginineserin rich protein topor realli interest new gene finger protein abil bind palindrom consensus dna sequenc enabl function potenti transcript regul howev role regul transcript cancer associ gene yet explor toll like receptor tlr agonist known regress solid tumor observ lipopolysaccharid lps induc topor via tlr tir domain contain adapt induc interferon depend pathway turn modul transcript tumor suppressor scaffoldmatrix attach region bind protein smar also known banp chip analysi show topor bind smar promot occup increas upon lps treatment previous studi laboratori reveal smar act repressor signal transduc activ transcript stat transcript tumor growth well tumor associ macrophag polar depend status stat stat ratio lps induc smar express decreas stat express also skew macrophag polar toward phenotyp contrast lps fail polar tumor associ macrophag phenotyp smar silenc condit show involv smar dictat fate colorect cancer progress identif molecular mechan behind lps mediat tumor regress would crucial design cancer treatment strategi involv bacteri compon | D015179;D051197 | T192;T191;T116 |
34,689,393 | antibacteri antibiofilm activ synerg florfenicol essenti oil lippia sidoid cymbopogon citratus aeromona hydrophila aeromona hydrophila opportunist bacterium high capac biofilm product caus sever damag aquacultur object studi identifi chemic compound essenti oil lippia sidoid eol cymbopogon citratus eocc evalu biocid antibiofilm synergist action antimicrobi florfenicol essenti oil eo hydrophila | D031743;D032411;D009822 | T002;T109 |
34,689,392 | target deliveri emamectin benzoat function polysuccinimid nanoparticl flower cabbag control plutella xylostella plutella xylostella one destruct cosmopolitan pest crucifer crop especi harm young tissu flower cabbag brassica campestri l although emamectin benzoat eb high insecticid activ p xylostella one major reason low util eb lack intern transport young plant | D001937;D007306;D007915;D009036;D053758 | T002;T073;T168;T131;T204 |
34,689,391 | function ferment meat product probiot review ferment import strategi preserv food use starter cultur probiot activ gain attent research produc function ferment meat product review aim overview main strength weak opportun threat ferment meat product probiot ferment meat product consid relev matrix deliveri probiot potenti health benefit moreov ferment meat product produc tradit method sourc probiot explor product function meat product howev barrier limit progress product complex select process obtain new tailor probiot strain current percept healthi associ meat meat product limit applic probiot ferment sausag promis opportun improv valu function ferment meat product develop explor new meat product function ferment food improv protect probiot microencapsul improv qualiti meat product reduc nitrat nitrat salt ad dietari fibr explor inher antioxid cardioprotect activ meat product attent potenti threat also indic unclear futur chang meat meat product consumpt due chang consum prefer presenc competitor dairi fruit veget base product instanc advanc stage develop commerci signific impact studi review provid overview strength weak opportun threat relat develop function ferment meat product probiot intern extern factor explain current scenario strategi advanc product highlight | D008461;D019936 | T007;T168 |
34,689,389 | reduc model uncertainti climat chang impact high latitud carbon assimil arctic boreal region abr larg impact global veget atmospher interact experienc mark greater warm rest planet trend project continu anticip futur emiss co abr signific sourc uncertainti estim carbon uptak terrestri biospher model reduc uncertainti critic accur estim global carbon cycl understand respons region global chang process represent parameter associ gross primari product gpp drive larg amount model uncertainti particular within next year respons exist veget climat chang domin estim gpp region review current understand model represent gpp northern latitud focus veget composit phenolog physiolog consid climat chang alter three compon highlight challeng abr predict gpp also focus uniqu opportun advanc knowledg model represent particular combin remot sens tradit boot ground scienc | D002244;D057231 | T070;T121;T196 |
34,689,388 | predat mitig destabilis effect heatwav multitroph stream communiti amidst global extinct crisi climat chang expos ecosystem frequent intens extrem climat event heatwav yet whether predat speci loss prevail characterist extinct crisi exacerb ecolog consequ extrem climat event remain larg unknown show loss predat speci interact heatwav moder composit stabil ecosystem expos multitroph stream communiti without domin predat speci realist current futur heatwav found heatwav destabilis algal communiti homogenis space howev happen predat absent addit heatwav impact multipl aspect stream communiti includ chang structur algal macroinvertebr communiti well total algal biomass tempor variabl appar heatwav emerg heatwav pass taken togeth result suggest ecolog consequ heatwav amplifi time impact propag biolog interact network presenc predat help buffer impact find underscor import conserv trophic structur highlight potenti speci extinct amplifi effect climat chang extrem event | D017753;D045483 | T070;T082 |
34,689,387 | qtc interv hour holter monitor trust trust qt interv repres ventricular depolar repolar accur measur critic sinc prolong qt lead sudden cardiac death qt affect heart rate correct qtc via sever formula qtc common calcul ecg h holter | D015716;D008133 | T033;T047;T060 |
34,689,386 | effect ethanol astaxanthin fatti acid product red yeast xanthophyllomyc dendrorh effect deterg ethanol ethanol plant meadowfoam oil growth red heterobasidomycet xanthophyllomyc dendrorh product astaxanthin dihydroxi caroten dion fatti acid red yeast investig | D001487;D001688 | T004;T121;T123 |
34,689,385 | effect spanish lockdown battl covid spatial analysi coronavirus propag across provinc paper examin propag covid across spanish provinc assess effect spanish lockdown popul implement march order battl pandem achiev object standard spatial econometr model use econom adapt resembl popular reproduct model employ epidemiolog literatur addit introduc counterfactu exercis allow us examin gross domest product gdp gain bring forward date spanish lockdown find number covid case would reduc absenc spatial propag spanish provinc also determin lockdown prevent propag virus within provinc spanish lockdown reduc number potenti covid case howev number coronavirus case would reduc addit lockdown brought forward march final earlier lockdown would save approxim euro | D000086382 | T047;T067 |
34,689,384 | novel lamc fusion protein tumor promot properti ovarian carcinoma laminin heterotrimer ecm protein compos chain chain lm frequent express monom express close associ cancer progress laminin contain epiderm growth factor egf like domain domain iii diii leb matrix metalloproteinas cleav diii region lm retain ligand activ egf receptor egfr herein show novel short form lm lm f contain diii generat without requir mmps chromosom transloc lamc chromosom nra gene locus chromosom human ovarian cancer skov cell laminin f express truncat form lack domain ii essenti associ lm chain lm secret lm f act egfr ligand activ egfrakt pathway effect lm chain turn promot prolifer surviv motil ovarian cancer cell lamc nra transloc detect use situ hybrid fusion transcript express ovarian cancer cell tissu overexpress suppress fusion transcript signific increas decreas tumorigen growth cell mous model respect best knowledg first report regard fusion gene ecm show transloc lamc play crucial role malign growth progress ovarian cancer cell consequ product promis therapeut target ovarian cancer | D015972 | T045 |
34,689,383 | decreas frequenc transplant lower post transplant surviv free transplant lvad patient new heart transplant alloc system evalu effect new heart transplant ht alloc system left ventricular assist devic lvad support patient list bridg transplant btt | D006333;D016027;D006353 | T074;T047;T061;T046 |
34,689,382 | predict valu egfr mutat non small cell lung cancer patient treat platinum doublet postop chemotherapi mutat status tumor tissu dna n resect stage ii iii non squamous non small cell lung cancer ns nsclc analyz use target deep sequenc exploratori biomark studi jipang tr jipang studi random phase iii studi pemetrexedcisplatin pemci vs vinorelbinecisplatin vnrcis tp mutat common egfr mutat exon delet lr kras mutat frequent detect frequenc egfr mutat signific among femal patient patient egfr mutat posit status signific shorter recurr free surviv rfs time mo vs reach hr ci p egfr mutat status multivari analysi identifi patholog stage egfr mutat status independ prognost factor rfs hr ci p diseas stage hr ci p egfr mutat status studi demonstr egfr mutat either poor prognost predict impact poor respons postop chemotherapi platinum doublet chemotherapi stage ii iii ns nsclc patient result support role mandatori molecular diagnosi earli stage ns nsclc precis oncolog signifi import adjuv rd generat tyrosin kinas inhibitor rather platinum base chemotherapi studi regist umin clinic trial registri umin | D009154 | T045 |
34,689,381 | toward improv definit periprocedur myocardi infarct role high sensit cardiac troponin past year mani disput optim biomark confirm rule diagnosi periprocedur myocardi infarct pmi optim cut concentr appli issu journal cardiac surgeri niclauss et al perform retrospect analysi ck mb high sensit cardiac troponin hs ctnt dynam peak concentr follow differ cardiac surgic intervent patient year period singl center author found ck mb hs ctnt predict pmi compar diagnost accuraci discriminatori power also attempt propos improv sensit threshold hs ctnt pmi find could implic clinic practic research warrant identifi appropri cut off could includ hs ctnt releas pattern slope steep chang ultim could result patient specif model abl predict expect abnorm rang hs ctnt releas enabl improv time diagnosi pmi | D009203;D020107 | T116;T047;T123 |
34,689,380 | warm elev co promot rapid incorpor degrad plant deriv organ matter ombrotroph peatland rise temperatur potenti direct affect carbon cycl peatland enhanc organ matter om decomposit contribut releas co ch atmospher turn increas atmospher co concentr may stimul photosynthesi potenti increas plant litter input belowground transfer carbon atmospher terrestri ecosystem key question remain magnitud rate interact oppos environment chang driver assess incorpor degrad plant microb deriv om ombrotroph peatland year whole ecosystem warm c two year elev co manipul ppm ambient show om molecular composit substanti alter aerob acrotelm highlight sensit acrotelm carbon rise temperatur atmospher co concentr warm acceler om decomposit ambient co new carbon incorpor peat increas warm elev co treatment plant microb deriv om use isotop signatur appli co enrich label recent photosynthes om data demonstr new plant input rapid incorpor peat carbon result suggest current hydrolog condit rise temperatur atmospher co level like offset boreal peatland | D002245;D017753 | T070;T082;T197;T123 |
34,689,377 | train direct care staff implement sensori integr strategi psychiatr inpati unit despit import sensori integr therapi psychiatr inpati unit continu pauciti train provid deliveri servic patient | D003695;D007297;D011568 | T058;T091;T093;T101 |
34,689,376 | sleep habit sleep problem associ depress symptom school age children sleep disturb characterist symptom depress also problem relat sever ill henc object studi examin sleep habit sleep problem associ increas depress symptom children | D003863;D012893 | T048;T047;T184 |
34,689,374 | express pattern cd cd identifi fine fibrovascular stroma grade endometri endometrioid carcinoma cytolog object studi assess diagnost util cd differenti diagnosi grade endometri endometrioid carcinoma g eec metaplast chang associ endometri glandular stromal breakdown egbd liquid base cytolog lbc sampl | D018269;D016889 | T191 |
34,689,372 | liver transplant donat control circulatori death versus brain death uno databas analysi public bias adjust meta analysi donat circulatori death dcd increas util altern donat brain death dbd expand liver donor pool compar outcom liver transplant lt dcd versus dbd | D016031;D009927 | T073;T055;T061;T058;T033 |
34,689,371 | impact oral health guidanc tongu lip motor function outpati dental hospit clarifi effect oral health guidanc tongu lip motor function outpati visit showa univers dental hospit tokyo japan | D008046;D009909 | T033;T023 |
34,689,370 | associ angptl polymorph high densiti lipoprotein cholesterol uptak capac patient cardiovascular diseas previous studi shown import angiopoietin like angptl modul lipid profil cholesterol uptak capac cuc one mean assess high densiti lipoprotein hdl function studi first time investig relationship genet angptl polymorph cuc patient cardiovascular diseas | D020641 | T086 |
34,689,369 | salari dispar base gender academ emerg medicin leadership signific fewer women men leadership role health care previous studi shown overal male physician earn near annual femal physician colleagu adjust confound factor howev descript physician leadership compens relat gender | D004635;D010822 | T091;T097 |
34,689,368 | molecular evolut converg rhodopsin gene gymnogobius gobi group diverg coastal freshwat habitat adapt evolut vision relat gene frequent observ process invas new environ wide rang anim taxa typic exampl molecular evolut rhodopsin associ habitat chang aquat anim howev studi investig rhodopsin evolut adapt radiat across various habitat present studi examin link molecular evolutionari pattern rhodopsin gene macroscop habitat chang gymnogobius speci gobiida adapt radiat divers aquat habitat includ sea brackish water river lake analysi amino acid substitut rhodopsin phylogenet framework reveal converg substitut amino acid three group four speci includ two spectral tune amino acid site known chang rhodopsin absorpt wavelength posit select detect basal branch three group suggest adapt molecular converg rhodopsin howev signific correl observ amino acid substitut speci habitat chang suggest molecular adapt unidentifi micro ecolog environ taken togeth result emphas import consid macroscop habitat also micro ecolog environ elucid drive forc adapt evolut visual system | D012243;D012641 | T070;T116;T045;T123 |
34,689,366 | fetal alcohol spectrum disord confabul psycholeg set beginn guid crimin justic forens mental health legal interview fetal alcohol spectrum disord fasd neurodevelopmentalneurobehavior condit caus prenat alcohol exposur pae impair caus pae contribut represent individu fasd unit state juvenil adult crimin justic system impair equal impact individu fasd wit victim crime also navig complex crimin justic system difficulti includ increas suscept confabul throughout legal process turn contribut increas rate poor outcom includ fals confess wrong convict individu fasd particular risk confabul subject tactic stress anxieti provok situat threat lead suggest coerciv question mani profession forens context unfamiliar fasd relat confabul risk may unintent util tactic intensifi impact pre exist impair articl serv beginn guid profession work crimin justic set provid research base overview fasd confabul b describ fasd may lead confabul c suggest way profession modifi protocol interact individu fasd suggest articl hold potenti decreas risk confabul crimin justic system decreas problemat outcom fals confess wrong convict among individu fasd | D063647;D011297 | T047;T019;T037 |
34,689,364 | week season variat circadian melatonin rhythm human respons read interest commentari skeldon dijk articl week season chronotyp depend variat dim light melatonin onset discuss point rais skeldon dijk current among hot debat human circadian scienc extern factor determin human phase entrain great contribut natur versus artifici light sun time versus social time intra individu data add still limit evid field studi matter commentari skeldon dijk formul two either hypothes postul human entrain either sole natur light dark cycl sun time referenc midday h sole light select local clock time social constraint h neither hypothesi account effect season human light exposur interpret find along complex line specul h earlier melatonin rise summer found sampl like combin result daylight save time dst induc behavior advanc stronger natur zeitgeb summer light exposur determin social season factor h origin show critic skeldon dijk base two sentenc quot context misrepres hypothesi h hypothesi h leav import season compon light exposur | D008550 | T121;T109;T125 |
34,689,363 | symbiont shuffl induc differenti dna methyl respons thermal stress coral montastraea cavernosa algal symbiont shuffl favour thermotoler speci shown enhanc coral resist heat stress yet mechanist underpin long term implic chang poor understood work studi modif coral dna methyl epigenet mechan involv coral acclimat respons symbiont manipul subsequ heat stress exposur symbiont composit manipul great star coral montastraea cavernosa control thermal bleach recoveri produc pair ramet three genet domin either nativ symbiont genus cladocopium thermotoler speci durusdinium trenchi singl base genom wide analys show signific modif dna methyl concentr intergen region intron transpos element remark dna methyl chang respons heat stress depend domin symbiont twice mani differenti methyl region found heat stress coral host differ symbiont cladocopium vs trenchii compar comparison interest differenti gene bodi methyl correl gene express enrich differenti methyl region evid repetit genom region overal result suggest chang algal symbiont favour heat toler associ accompani chang dna methyl coral host implic result coral adapt along futur avenu research base current knowledg gap discuss present work | D037421;D004141 | T204 |
34,689,362 | switch associ protein protect nonalcohol fatti liver diseas suppress tak nafld progress diseas without known effect drug treatment switch associ protein swap guanin nucleotid exchang factor particip regul mani cellular process howev role swap nafld remain unclear studi aim identifi function mechan swap nafld | D007333;D065626 | T047;T046 |
34,689,361 | sexual offend treatment prison base social therapeut treatment complet relationship risk factor recidiv releas various studi demonstr peopl complet sex offend treatment higher recidiv rate complet untreat control mechan behind associ howev remain unclear one explan respons issu preval high risk offend make treatment failur recidiv like especi treatment intens insuffici match crimin need addit dropout may negat effect offend increas feel frustrat self doubt | D057237;D000075665;D012742 | T037;T048;T098 |
34,689,360 | chang pattern pediatr anaphylaxi hong kong anaphylaxi signific health burden western countri littl publish data incid pattern anaphylaxi asia aim determin incid rate pattern anaphylaxi past decad among pediatr popul hong kong | D000707;D005512 | T047;T046 |
34,689,359 | fine needl aspir cytolog dermatofibrosarcoma protuberan aris burn scar tumour develop protract period time burn scar notabl complic carcinoma form major share occurr burn scar sarcoma scarc dermatofibrosarcoma protuberan dfsp uncommon entiti three prior report case author report case year old male patient year prior histori thermal burn present expand painless swell year right flank region diagnos dfsp fine needl aspir cytolog subsequ confirm histopatholog | D002056;D018223;D012878 | T191;T037 |
34,689,356 | setal descript locat abund impact decor behavior spider crab libinia crustacea epialtida setal abund distribut spider crab libinia examin use two speci spider crab decor bodi environment materi camouflag predat decor attach hook seta type seta preval bodi region decor occur adult crab undergo termin molt lose abil regrow seta littl known setal chang lifetim crab hook seta abund decreas age result loss camouflag strategi larger individu object studi determin preval abund hook non hook seta decor bodi region setal pattern vari speci bodi size scan electron microscopi use along comput softwar describ count measur setal coverag hook non hook seta bodi region small individu hook seta larger individu two speci differ setal abund hook non hook seta non hook seta cover much surfac area crab attach decor remain crab even hook seta damag broken setal morpholog foul describ among differ size crab two speci setal type morpholog similar foul differ larg individu like employ differ camouflag strategi small individu due lose hook seta retain non hook seta | D003445;D013112 | T204 |
34,689,355 | sand accumul digest tract rabbit oryctolagus cuniculus guinea pig cavia porcellus role appendix determin locat amount accumul sand gastrointestin tract git rabbit oryctolagus cuniculus guinea pig cavia porcellus fed diet contain extern silic abras comput tomograph abdomin imag rabbit n guinea pig n receiv vari number differ diet day total n comput tomograph radiograph dissect git presenc silica git content n anim evalu rabbit major accumul sand locat caecal appendix elong intestin structur left side abdomen wash back colon separ mechan rabbit may part respons retrograd transport sand back caecum dens small particl accumul appendix appendix like act reservoir particl lead signific effect momentari also previous diet record sand volum rabbit guinea pig caecal appendix colon separ mechan base wash back less sand accumul found git without specif locat pattern less previous diet effect speci none rabbit guinea pig develop clinic sign obstruct studi record sand volum repres sand intak rabbit guinea pig accumul sand volum cm git rabbit seem caus clinic health impair larg inter individu differ rabbit indic inter individu variat prone sand accumul reason presenc sand trap caecal appendix anim due burrow lifestyl feed close ground predestin accident sand ingest remain unveil | D000821;D001065 | T023;T168 |
34,689,354 | genet intervertebr disc diseas review intervertebr disc diseas ivdd common musculoskelet diseas affect individu character lumbar disc herniat caus nerv root irrit either mechan via inflammatori mediat result radiat pain known sciatica numer studi conduct identifi caus risk factor ivdd lift heavi load torsion stress motor vehicl drive among best identifi environment risk factor howev becom evid recent famili twin studi genet factor may also import ivdd hypothesi strengthen identif two collagen ix allel associ sciatica lumbar disc herniat addit disc degener shown relat aggrecan gene polymorph vitamin receptor matrix metalloproteinas gene allel review highlight genet role occup aspect ivdd | D007403;D055959;D007405 | T190;T047;T023 |
34,689,353 | convent spectral ct imag translat augment workflow robust contrast inject independ organ segment comput tomographi ct cardiovascular imag numer contrast inject protocol use enhanc structur make difficult gather train dataset deep learn applic support divers protocol moreov creat annot noncontrast scan extrem tedious recent spectral ct virtual noncontrast imag vnc use data augment train segment network perform enhanc true noncontrast tnc scan alik improv result protocol absent train dataset howev spectral data wide avail make difficult gather specif dataset task solut present data augment workflow base train imag translat network bring spectral like augment convent ct dataset | D013909;D014057 | T029;T060 |
34,689,352 | virtual augment realiti new tool visual analyz communic complex morpholog virtual augment realiti vrar new technolog power revolution studi morpholog modern imag approach comput tomographi laser scan photogrammetri open new digit world enabl research share analyz morpholog data electron great detail digit data exist comput screen howev remain difficult understand unintuit interact vrar technolog bridg analog digit divid present data user similar way would interact actual anatomi also provid immers experi greater possibl explor manuscript describ vrar hardwar softwar techniqu design give practic morphologist educ primer use technolog research pedagogi communic wide varieti audienc also includ seri case studi present workshop given intern congress vertebr morpholog suggest best practic use vrar compar morpholog | D000081411;D000076142 | T170;T066 |
34,689,351 | valu basophil activ test evalu patient report allerg reaction bntb mrna covid vaccin mrna base covid vaccin report induc hypersensit reaction hsr small number individu aim evalu real world incid bntb mrna covid vaccin hsr determin valu basophil activ test bat allergolog workup patient report reaction | D000086382;D004342 | T046;T047;T067 |
34,689,350 | allel genotyp frequenc cypa cypa cypa gstp gene polymorph among mainland tibetan mongolian uyghur han chines popul prescrib drug metabolis cytochrom p cypa glutathion transferas pi gstp add glutathion oxid product cypa increas hydrophil properti metabolit facilit excret singl nucleotid polymorph snps cypa gstp show divers allel genotyp frequenc distribut among world popul present studi aim investig genotyp allel frequenc distribut pattern cypa cypa cypa gstp polymorph among healthi particip mainland tibetan mongolian uyghur han chines popul blood sampl collect unrel healthi subject tibetan mongolian uyghur han genotyp analysi variant allel frequenc cypa rs cypa rs cypa rs gstp ilev observ han tibetan mongolian uyghur respect allel frequenc cypa c uyghur higher tibetan p strong linkag disequilibrium cypa rs cypa rs cypa rs among four ethnic group result might use precis medic chines popul | D051544;D020641 | T086;T116;T126 |
34,689,349 | role tazobactam base combin manag infect due extend spectrum lactamas produc enterobacteral insight societi infecti diseas pharmacist extend spectrum lactamas esbl produc enterobacteral global threat public health due antimicrobi resist profil consequ limit avail treatment option tazobactam sulfon lactamas inhibitor vitro inhibitori activ common esbl enterobacteral includ ctx howev role tazobactam base combin treat infect caus esbl produc enterobacteral remain unclear unit state two tazobactam base combin avail piperacillin tazobactam ceftolozan tazobactam evalu compar role tazobactam base combin esbl produc organ emphasi pharmacokineticpharmacodynam exposur relat mic distribut establish breakpoint clinic outcom data specif infect site consider downstream effect agent regard antimicrobi resist develop limit data ceftolozan tazobactam encourag potenti role infect due esbl produc enterobacteral evid need determin place therapi convers current avail microbiolog pharmacokinet pharmacodynam clinic data suggest role piperacillin tazobactam caution clinician usag infect | D004756;D000078142;D001618 | T116;T047;T121;T109;T195;T126 |
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