PMID int64 27.8M 36.2M | Title/Abstract stringlengths 7 10.7k | MeshTerms stringlengths 7 104 | SemanticTypes stringlengths 4 84 |
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34,688,252 | thelazia callipaeda infect phacoemulsif cataract surgeri case report august found one case thelazia callipaeda infect phacoemulsif cataract surgeri mayb first report thelazia callipaeda discov phacoemulsif cataract surgeri china | D002386;D018918;D017205;D013802 | T047;T190;T204;T061;T033 |
34,688,250 | larotinib patient advanc previous treat esophag squamous cell carcinoma epiderm growth factor receptor overexpress amplif open label multicent phase b studi larotinib new first generat epiderm growth factor receptor egfr tyrosin kinas inhibitor open label phase b studi aim evalu efficaci safeti larotinib patient advanc esophag squamous cell carcinoma escc egfr overexpress amplif pretreat one system regimen recommend appropri dose studi | D000970;D002289;D004938;D000077277;D008175 | T191;T121;T109 |
34,688,249 | incid mortal yellow fever africa systemat review meta analysi understand occurr yellow fever epidem critic target intervent control effort reduc burden diseas assess data yellow fever incid mortal rate africa | D015004 | T047 |
34,688,248 | emerg depart admiss intens care unit nation retrospect studi emerg depart ed see rise number patient small fraction ed patient need immedi intens care characterist patient most unknown reason believ larg inter hospit differ threshold intens care admiss ed purpos studi give nationwid overview ed admiss direct intens care unit | D007362;D010343 | T058;T093;T073 |
34,688,247 | use multi layer perceptron identifi origin replic eukaryot via inform featur origin start site dna replic extrem vital part inform inherit parent children import accur identifi origin replic great applic valu diagnosi treatment diseas relat genet inform error tradit biolog experiment method time consum labori | D004331;D056890 | T204 |
34,688,246 | tagopsin collat taxa specif gene protein function structur inform wealth biolog inform avail nowaday public databas trigger unpreced rise multi databas search data retriev obtain detail inform key function structur entiti concern investig rang gene genom analysi protein structur analysi howev retriev interconnect data number differ databas often done repeat unsystemat way | D011506;D012984 | T116;T073;T123;T170;T090 |
34,688,245 | potenti role human hiv tat interact protein level pathogenesi contact dermat human hiv tat interact protein htatiptip gene extens express human tissu well tumor tissu studi aim explor potenti role htatiptip contact dermat cd one common inflammatori cutan condit | D015497 | T005 |
34,688,225 | evalu predict method glomerular filtrat optimis drug dose obes nonobes patient suitabl method predict glomerular filtrat rate gfr obes current debat therefor multipl gfrcreatinin clearanc predict method appli morbid obes nonobes patient rang moder renal impair glomerular hyperfiltr predict rate base observ fosfomycin pharmacokinet model drug exclus elimin via glomerular filtrat | D005578;D051436 | T195;T047;T109 |
34,688,224 | anti inflammatori potenti lactobacillus reuteri lm via eicosanoid regul lps stimul raw cell investig anti inflammatori effect lactobacillus reuteri lm lipopolysaccharid lps induc inflamm raw cell | D052200 | T007 |
34,688,221 | test protocol optim heart rate base lactat minimum test determin maxim lactat steadi state mlss requir least two constant load test therefor differ test procedur indirect determin mlss base one singl test develop one method applic lactat minimum test lmt workload heart rate base protocol exist latter show signific correl paramet lactat minimum lm mlss run cycl howev lm clear underestim mlss therefor aim studi optim alreadi exist test protocol term improv agreement lm mlss fourteen healthi endur train male athlet age height cm bodi mass kg perform four differ heart rate base lmt protocol origin three new protocol addit perform sever constant heart rate endur test assess mlss exercis intens heart rate blood lactat concentr oxygen uptak power lm two new test protocol increas start intens closer longer differ mlss data conclud two new test protocol use practic estim heart rate base mlss mean one singl exercis test | D005080;D019344 | T109;T121;T060;T123 |
34,688,220 | sa involv myocardi injuri induc exhaust exercis mani studi confirm exhaust exercis advers effect heart generat reactiv oxygen speci ros sa calcium bind protein sa regul myocardi contractil protector myocardi injuri howev studi investig role sa regul myocardi injuri induc exhaust exercis present studi suggest exhaust exercis led increas ros downregul sa myocardi injuri downregul sa promot exhaust exercis induc myocardi injuri overexpress sa revers oxid stress induc cardiomyocyt injuri indic sa protect factor myocardi injuri caus exhaust exercis also found downregul sa promot damag critic protein mitochondria inhibit express ant pgca tfam exhaust exercis studi indic sa potenti prognost biomark therapeut target improv myocardi damag induc exhaust exercis provid new insight molecular mechan under myocardi injuri effect exhaust exercis | D009206;D009418 | T116;T024;T123 |
34,688,219 | superfici circumflex iliac arteri perfor flap elev use preoper high resolut ultrasonographi vessel map flap design superfici circumflex iliac arteri scia perfor scip flap gain accept among reconstruct microsurgeon minim donor site morbid greatest advantag purpos articl introduc use preoper ultrasonographi facilit elev avoid postop complic scip flap | D007083;D011300;D019651 | T058;T023;T061 |
34,688,218 | comparison various modal util preoper plan microsurg reconstruct surgeri benefit preoper perfor imag microsurg reconstruct well establish literatur | D061525;D019651 | T023;T061 |
34,688,217 | microsimuc valid low cost portabl microsurgeri train kit microsurgeri depend larg simul train acquir skill cours offer worldwid usual short intens depend physic laboratori object develop valid portabl low cost microsurgeri train kit | D007396;D000066908 | T097;T065 |
34,688,216 | role sex steroid prostaglandin luteal life cycl domest cat lynx although lynx domest cat felid luteal life cycl differ mani speci corpora lutea cls domest cat regress pregnanc pseudopregn contrast cls lynx function regress follow cycl format stay physiolog activ persist sever year obtain improv understand life cycl speci compar studi cls speci detail review summar similar differ cls regard sex steroid prostaglandin generat receptor evid differ visibl cls lynx persist previous cycl compar cls lynx domest cat recent luteal cycl assum differ could indic process ensur long term luteal surviv function exampl high estrogen productionmetabol antioxid effect | D046008 | T015 |
34,688,215 | plane nutrit fsh induc superovul affect express steroid hormon receptor growth factor caruncular tissu non pregnant sheep implant critic step establish pregnanc import part embryo matern contact uterin recept affect chang bodi condit matern endocrin milieu includ caus use exogen gonadotropin control ovarian hyperstimul induc develop multipl follicl studi demonstr effect fsh mediat ovarian hyperstimul caruncl ewe various feed regim sheep classifi categori control fed cf overf underf uf group anim superovul fsh inject salin solut non treat control uterin caruncl collect earli mid luteal phase estrous cycl transcript level steroid hormon receptor esr esr pgr growth factor igf igf vegfa investig express local immunohistochem stain main find day estrous cycl affect express esr igf igf esr pgr vegfa feed superovul modulatori effect feed ufof stimul express gene studi superovul alter express gene eg igf pgr esr esr cf anim similar feed ufof alter respons superovul pgr esresr andor data emphas possibl effect dietari andor hormon stimuli uterin physiolog may affect pregnanc outcom disrupt uterin function | D005640;D013480 | T033;T116;T121;T125 |
34,688,214 | cell cancer origin provid reliabl roadmap diagnosi prognosi biolog therapi cancer aris singl transform cell virtual everi organ bodi divid relat uncontrol manner metastas wide search magic bullet precis diagnos character ultim treat cancer larg fail cancer cell differ signific organ specif cell origin instead search genom epigenet transcript translat differ cancer cell origin paradox focus cancer cell common untransform cell origin redirect search lead improv diagnost therapeut strategi therapeut index consider drug limit toxic larg circumv cite three cancer exampl illustr paradigm shift strategi pseudomyxoma peritonei pp metastasi unknown origin cancer unknown primari muo cancer aris potenti dispens organ cad exampl cell cancer origin still provid reliabl road map diagnosi prognosi biolog therapi | D010534;D011553 | T191 |
34,688,213 | hospit revisit post ischem stroke epilepsi acut stroke intervent improv acut stroke care led increas ischem stroke survivor risk develop post ischem stroke epilepsi pise impact therapi thrombectomi thrombolysi risk hospit revisit pise unclear util administr data investig associ stroke treatment pise relat visit | D004827;D000083242;D010359 | T058;T033;T047 |
34,688,212 | continu quantit electroencephalogram eeg monitor earli detect brain herniat larg hemispher infarct lhi case report comput assist electroencephalographi eeg system may improv likelihood detect abnorm eeg adult patient sever diseas | D020520;D004677 | T190;T047;T019;T020 |
34,688,211 | transcrani doppler h success reperfus predictor infarct volum aim studi analyz hemodynam chang middl cerebr arteri mca endovascular revascular acut ischem stroke ai due larg vessel occlus associ infarct volum size control head ct | D020244;D000083242 | T047;T020 |
34,688,210 | stent open visual mechan thrombectomi relationship retriev clot procedur success angiograph visual stent mechan thrombectomi mt may provid inform regard characterist under occlud clot devic clot interact recan purpos studi evalu open stent sign relat retriev clot recan | D000083242;D061185;D015607 | T074;T047;T061 |
34,688,209 | gait differ children age without potenti depress mood report depress impact tempor spatial paramet walk kinemat adult given differ walk biomechan adult children studi aim compar gait differ children age without potenti depress mood pdm | D003863;D005684 | T033;T048;T184 |
34,688,208 | compar perform analysi gamma metric patient specif qa vmat use octavius array gamma pass percentag gpp predomin metric use patient specif qualiti assur psqa radiat therapi dimension measur geometri psqa evolv planar planar present state art volumetr geometri aim critic examin perform three dimension gamma vis vis older gamma metric lower dimension determin mutual fungibl psqa use clinic approv volumetr arc therapi vmat plan | D019985;D050397 | T061;T081 |
34,688,207 | feasibl studi plan transform novel workaround enabl patient transfer differ varian machin object work explor methodolog enabl plan transfer standard mlc std high definit mlc hd varian unit without replan use plan transform aim util full department capac dispers patient std varian unit hd unit former goe repair | D010360;D050397 | T058;T061 |
34,688,206 | gene regulatori circuitri plant environ interact scale cell field plant growth develop product layer sens regul modul multifactori environment cue innov genom current allow gene regulatori control quantifi multipl scale high resolut defin cell popul even individu cell nuclei plant applic omic technolog high control well field environ revolution recognit factor critic spatial tempor respons singl multipl environment cue within pan speci comparison illumin deepli conserv circuitri target select knowledg benefit breed engin crop greater resili climat variabl abil augment nutrit plant microbi interact | D018556;D000069600 | T040;T002 |
34,688,203 | identifi pediatr patient multisystem inflammatori syndrom children present pediatr emerg depart compar clinic laboratori featur children multisystem inflammatori syndrom children mis c evalu mis c emerg depart ed | D002097;D008231 | T129;T047;T116 |
34,688,202 | virtual resid interview experi child neurolog resid program perspect covid pandem present mani challeng graduat medic educ includ need quick implement virtual resid interview investig differ program approach challeng determin best practic | D004503;D007396;D007407;D049269 | T065;T052;T066;T097;T062 |
34,688,201 | discov main reinforc kidney strengthen yang activ compon salt morinda officinali base spectrum effect relationship combin chemometr method morinda officinali well known tradit herbal medicin china use treat defici kidney yang syndrom although medicin properti reinforc kidney strengthen yang chemic constitu respons effect remain elucid aim identifi main activ compound respons reinforc kidney strengthen yang base spectrum effect relationship combin chemometr use uplc diod array detect method establish chromatographi fingerprint officinali hydrocortison induc adenin induc kidney yang defici pattern establish evalu efficaci officinali serum triiodothyronin free thyroxin thyrotropin testosteron cortisol lutein hormon follicl stimul hormon corticotropin releas hormon adrenocorticotrop hormon level determin pharmacodynam indic analyt hierarchi process use determin weight index total pharmacodynam contribut last spectrum effect fingerprint pharmacolog effect establish use grey relat analysi partial least squar find indic peak might repres main compon posit correl total effect four identifi comparison refer standard identifi compon monotropein peak deacetyl asperulosid acid peak asperulosid acid peak asperulosid peak result suggest reinforc kidney strengthen yang effect attribut combin effect multipl chemic compon officinali provid valuabl method identifi activ reinforc kidney strengthen yang compon officinali establish qualiti control officinali | D004365;D032066 | T121;T002;T123 |
34,688,200 | develop person center popul base measur home time perspect older patient unpaid caregiv measur home time number day facil base care medic claim promis approach assess person center outcom popul level general spend time home match long term care prefer improv qualiti life howev exist home time measur incorpor key stakehold perspect sought understand patient famili caregiv valu time spent divers facil base health care set emerg depart nurs home post acut careskil nurs inpati hospit help determin whether various set differ effect qualiti life thus merit differ weight home time measur conduct three focus group among patient famili caregiv within us veteran health care system identifi theme pertain patient qualiti life four facil base care set discuss emerg depart post acuteskil nurs care reflect loss person control counterbalanc temporari stay inpati hospit care evok discuss greater loss person control due intens care nurs home ultim signifi declin find illumin differ qualiti life across health care set help justifi need differ weight measur home time | D017028;D011788 | T097;T078;T098;T099 |
34,688,196 | hybrid catalyst cascad enhanc oxid glucos glucoseair biofuel cell redox enzym capabl harvest electr energi biofuel high catalyt activ mild condit howev difficult achiev effici electron transfer deep oxid biofuel simultan singl enzym catalyt system herein report hybrid catalyst cascad consist organ oxid catalyst tetramethyl piperidin n oxyl tempo enzym glucos oxidas gox electrochem oxid glucos found tempo capabl mediat electron transfer redox center gox electrod surfac glucos oxid glucuron acid neutral condit thus combin gox tempo abl achiev e electrooxid glucos use hybrid enzymat organ cascad heoc system coupl air breath pt cathod result glucoseair biofuel cell use propos heoc anod exhibit maximum power densiti w cm short circuit current cm attribut enhanc energet effici enabl tempo promis catalyst glucos oxid bioelectron applic | D001674 | T074;T073 |
34,688,195 | overexpress watermelon methyltransferas clmtb enhanc drought toler tobacco mitig oxid stress photosynthesi inhibit modul stress respons gene express n methyladenosin rna import post transcript modif mechan eukaryot report import regulatori role stress respons model plant research regard modif watermelon studi clone character methyltransferas clmtb mrna adenosin methylas b mettl human homolog protein watermelon clmtb express could weak induc drought stress determin quantit real time pcr qrt pcr promot gus analys clmtb express tobacco plant increas drought toler via enhanc reactiv oxygen speci ros scaveng system allevi photosynthesi inhibit drought transcriptom profil indic multipl hormon stress respons gene specif induc express clmtb plant drought condit result suggest clmtb mediat modif serv posit regulatori factor drought toler studi first one provid understand specif role clmtb watermelon adapt drought stress may also provid import insight signal pathway mediat modif respons stress condit | D029773;D014026 | T002;T168 |
34,688,194 | activ cdc acetyltransferas encod gene contribut enhanc abiot stress toler improv product trait rice world wide crop product high impact various extrem environment condit present investig activ tag line ds rfp rice endow improv agronom attribut test toler abil drought salin stress condit well identif gene associ trait drought salin stress condit ds rfp line exhibit increas seed germin rate improv plant growth characterist seedl veget reproduct stage compar wild type wt plant moreov ds rfp reveal effect antioxid system result decreas accumul reactiv oxygen speci delay stress symptom compar wt plant reduc accumul malondialdehyd concomit increas prolin solubl sugar ds rfp line endors improv stress toler level furthermor ds rfp disclos enhanc plant water content photosynthet effici stomat conduct water use effici maximum quantum yield compar wt plant tail qrt pcr analys rice line reveal integr site ds element genom increas express level cdc acetyltransferas gene involv various aspect plant develop stress toler promis line plausibl serv rare genet resourc fortifi stress toler product trait elit rice cultivar | D012275 | T002;T168 |
34,688,193 | suppli pharmaceut care servic key new model health servic interdisciplinari collabor health profession essenti improv health outcom compet pharmacist make profession capabl contribut comprehens manag pharmacotherapi collabor healthcar profession council europ adopt resolut cmres implement pharmaceut care benefit patient health servic order promot appropri safe use medicin one activ carri pharmaceut care process detect drug relat problem contraind duplic prescript error interact etc mani case involv regular patient follow need evalu intervent perform requir establish appropri interprofession collabor framework articl discuss issu address face chang model toward care base pharmaci | D003157;D010593;D010594;D010604 | T057;T073;T170;T091;T093;T058 |
34,688,192 | respons soi microdosimet fast neutron beam experi mont carlo simul studi mont carlo code geant mcnp use character fast neutron therapeut beam produc ithemba lab south africa experiment simul result compar use latest generat silicon insul soi microdosimet centr medic radiat physic cmrp geant mcnp abl success model neutron gantri simul expect neutron energi spectrum produc reaction proton bombard target neutron beam simul water phantom characterist record silicon microdosimet bare cover b enrich boron carbid convert differ posit microdosimetr quantiti calcul use geant mcnp agreement experiment measur thermal neutron sensit product b captur product p boron implant dopant region bridg microdosimet investig obtain result use futur develop dedic soi microdosimet boron neutron captur therapi bnct paper provid benchmark comparison geant mcnp capabl context applic code neutron microdosimetri | D016754;D005214 | T061;T081 |
34,688,191 | white matter chang drug nave parkinson diseas patient impuls control probabl rem sleep behavior disord accord epidemiolog studi parkinson diseas pd patient probabl rem sleep behavior disord prbd prone develop impuls control disord icd shown present drug nave pd patient vice versa | D010300;D004364;D020187;D066127 | T047;T121;T023;T048;T024 |
34,688,190 | hospit base observ studi neurolog disord patient recent vaccin covid mrna vaccin describ spectrum acut neurolog disord among hospit patient recent covid mrna vaccin | D000086382;D009422 | T047;T067 |
34,688,189 | pathophysiolog vasovag syncop novel insight pathophysiolog vasovag syncop vvs review focus hemodynam aspect much known orthostat emot vvs probabl former studi use tilt tabl test ttt recent advanc made possibl quantifi relat contribut three factor control blood pressur heart rate hr stroke volum sv total peripher resist tpr orthostat vvs start venous pool reflect decreas sv follow cardioinhibit ci decreas hr acceler ongo decreas bp make start ci liter well fundament turn point role hormon humor factor respir psycholog influenc review short lead conclus multidisciplinari approach studi pathophysiolog vvs may yield new insight | D019462 | T047 |
34,688,188 | relianc vascular respons mainten blood pressur healthi older adult insight valsalva maneuv effect baroreflex mediat cardiac vascular resist respons crucial homeostat blood pressur control investig impact age sex arteri blood pressur regul standard supin valsalva maneuv mmhg healthi young healthi older adult noninvas continu cardiovascular paramet record older adult cardiac output older young p stroke volum older young p fell young adult compens augment vascular resist respons older young p heart rate respons attenu older adult male femal respons compar respect age group | D017704;D014636 | T042;T060 |
34,688,186 | determin morphin codein thebain concentr poppi seed tea use magnet carbon nanotub facilit dispers micro solid phase extract gc ms analysi tighten enforc restrict amid opioid epidem poppi seed tea consum altern mitig withdraw symptom home remedi reliev pain stress previous publish studi suggest potenti danger consum tea brew moder larg amount poppi seed studi effect small quantiti repeat brew opiat concentr evalu dispers micro solid phase extract facilit magnet carbon nanotub mag cntsd spe develop optim success valid appli ten poppi seed tea sampl use gas chromatographi mass spectrometri gc ms analysi total ten poppi seed sampl evalu work two gram bulk poppi seed brew ml heat acidifi di water three time brew tea sampl subject valid mag cntsd spegc ms analysi total mean opiat concentr obtain three brew mgkg morphin codein thebain respect total opiat yield obtain small quantiti brew ie g seed ml tea studi may provid minim analges euphor effect total opiat yield extract first brew acidifi deioniz water min brew period opiat yield second third brew minim howev potenti overdos could occur tea sampl scale starter quantiti seed suggest new user | D037742;D010207 | T104;T002;T073 |
34,688,185 | legal impact forens medic life threaten danger assess conclus case violent offens aim studi examin associ legal outcom suspect perpetr forens life threaten danger assess conduct part clinic forens medic examin victim penetr injuri | D019548;D014950 | T037;T068;T098 |
34,688,184 | prognost capac inferior vena cava diamet sever postpartum hemorrhag studi sought evalu whether sonograph measur inferior vena cava ivc diamet predict sever bleed women postpartum hemorrhag pph compar efficaci ivc diamet shock index serum lactat level predict | D006473;D014682 | T023;T046 |
34,688,183 | evalu long term effect complic rate singl incis sling femal stress urinari incontin evalu long term outcom singl incis midurethr sling sim real life practic | D053825;D014550 | T047;T074 |
34,688,182 | person chang patient suffer drug resist epilepsi surgic treatment year follow studi determin chang dimens person sampl patient suffer drug resist epilepsi year follow follow surgeri compar non surgic treat control | D001007;D004827 | T047;T184;T041;T048;T033 |
34,688,181 | earli onset extern behavior among forens psychiatr patient identif child adolesc psychiatr servic forens psychiatr patient constitut heterogen patient group common comorbid within extern spectrum increas knowledg earli anteced pathway sever mental ill crimin need studi investig earli onset extern behavior three group forens psychiatr patient patient without contact child adolesc psychiatri cap patient cap contact patient cap contact institut placement particip n consecut recruit cohort forens psychiatr patient sweden data collect file inform semi structur interview analyz bayesian approach histori cap togeth institut placement childhood adolesc associ extern disord higher number convict lifetim lower age first convict lower age first self report crime find provid insight import earli onset advers behavior develop later extern behavior may particular use practition within social servic cap servic | D000296;D002665;D003134;D005555;D001523 | T091;T048;T089;T064 |
34,688,180 | ultrastructur chang associ neuroendocrin transdifferenti lung adenocarcinoma cell line neuroendocrin transdifferenti found mani cancer cell type prostat lung gastrointestin cell accompani lower patient life expect transdifferenti process induc vitro exposur differ stimuli human lung adenocarcinoma aim work identifi morpholog characterist neuroendocrin phenotyp human lung cancer cell line induc two camp elev agent ibmx fsk result show two phenotyp one produc ibmx higher volum cell size increas number secondari project produc fsk higher area rough membran cell neurit percentag number outgrowth per cell increas number primari project conclus describ morpholog ultrastructur characterist neuroendocrin phenotyp human lung cancer cell line promot ibmx fsk contribut understand autocrin paracrin signal within tumor microenviron | D000077192;D054338;D008175 | T043;T191 |
34,688,179 | assess differenti sensit wave caipi vista myelin water fraction magnet transfer satur effici quantifi tissu damag ms wave caipi visual short transvers relax time compon vista recent develop short sensit mri method fast quantif myelin water fraction mwf human brain repres promis techniqu evalu subtl earli signal demyelin cerebr white matter multipl sclerosi ms patient current howev studi exist robust assess util vista mwf measur myelin compar convent mri measur myelin brain ms patient moreov previous studi evalu sensit vista mwf non invas detect subtl tissu damag normal appear white matter nawm white matter lesion ms patient result central purpos studi systemat evalu relationship myelin sensit base vista mwf map general recogn metric magnet transfer satur mt sat healthi control ms brain white matter | D009103;D066127 | T023;T047;T024 |
34,688,177 | heteronuclear transfer labil proton biomolecular nmr cross polar revisit inept hmqc base puls sequenc wide use transfer polar heteronuclei particular biomolecular spectroscopi easi setup involv low power deposit still short puls polar transfer scheme challeng fast solvent chemic exchang altern improv heteronuclear transfer j driven cross polar j cp transfer polar spin lock coupl spin hartmann hahn condit j cp provid certain immun chemic exchang like relax effect behavior examin depth liouvill space numer analyt deriv describ transfer effici superior inept base transfer fast exchang may also slow j cp transfer hurt effici studi therefor explor potenti repeat project oper improv h n h n c j cp transfer presenc fast solvent chemic exchang found repeat j cp provid littl h n transfer advantag prolong cp multipl contact keep water labil proton effect spin lock improv h n c transfer presenc chemic exchang ensu loop concaten cross polar l ccp compens singl j cp loss reli c longer lifetim lead kind algorithm cool provid high polar n well carbonyl alpha cs facilit certain experi demonstr tripl reson experi intrins disord protein involv labil chemic exchang proton | D064267;D011522 | T116;T196;T123 |
34,688,176 | exposur american lobster homarus americanus pesticid chlorpyrifo result chang gene express chlorpyrifo organophosph current use reduc arthropod pest protect agricultur crop coastal marin ecosystem may expos agricultur pesticid via runoff pesticid exposur impact health surviv non target speci american lobster homarus americanus current studi gene express chang h americanus stage iv larva evalu understand physiolog mechan affect exposur subleth concentr chlorpyrifo h chlorpyrifo exposur surviv lobster process illumina rna sequenc rna seq gene interest show signific chang use rna seq verifi use revers transcriptas quantit polymeras chain reaction rt qpcr analysi rna seq confirm gene express pattern via rt qpcr found alter express gene relat stress respons glutathion peroxidas heat shock protein hypoxia respons hairi astakin hemocyanin moult cytochrom p chitinas immun astakin pathway chang gene express notabl lobster expos gl chlorpyrifo | D004390;D010575 | T131;T109 |
34,688,175 | thermal physic damag skull base drill use gas cool mode fem simul experiment evalu skull base drill high risk process one import techniqu skull base surgeri | D003080;D019637 | T070;T061 |
34,688,174 | micro surgic anastomos workflow recognit challeng report automat surgic workflow recognit essenti step develop context awar comput assist surgic system video record surgeri becom wide access oper field view captur laparoscop surgeri head ceil mount camera also increas use record video open surgeri make video common choic surgic workflow recognit addit modal kinemat data captur robot assist surgeri could also improv workflow recognit paper present design result micro surgic anastomos workflow recognit train session misaw challeng whose object develop workflow recognit model base kinemat data andor video | D010535;D065287 | T061;T060 |
34,688,173 | convolut neural network train dermoscop imag psoriasi perform par dermatologist psoriasi common chronic inflammatori skin diseas caus physic psycholog burden patient convolut neural network cnn focus dermoscop imag would substanti aid classif increas accuraci diagnosi psoriasi | D008545;D011565;D012878 | T191;T047 |
34,688,172 | larg margin piecewis linear classifi fusion deep featur diagnosi covid world experienc epidem coronavirus infect sever time last two decad recent studi shown use medic imag techniqu use develop automat comput aid diagnosi system detect pandem diseas high accuraci earli stage studi larg margin piecewis linear classifi develop diagnos covid compar wide rang viral pneumonia includ sar mer use chest x ray imag propos method preprocess pipelin employ moreov deep pre post rectifi linear unit relu featur extract use well known vgg net fine tune optim transfer learn afterward canon correl analysi perform featur fusion fuse deep featur pass lmpl classifi introduc method reach highest perform comparison relat state art method two differ scheme normal covid typic viral pneumonia covid sar mer pneumonia classif accuraci respect | D000086382;D000077321;D011024 | T047;T066;T067 |
34,688,171 | higher reproduc phase deriv metric electrocardiograph imag atrial fibril patient remain sinus rhythm pulmonari vein isol electrocardiograph imag ecgi allow evalu complex reentrant activ atrial fibril af patient studi evalu abil ecgi metric predict success pulmonari vein isol pvi treat af | D001281;D017115;D011667 | T023;T047;T061;T046 |
34,688,170 | translat suppress sar cov orf protein mrna viabl therapeut target covid comput studi potenti role isol compound clerodendrum volubil leav open read frame orf protein sar cov implic onset cytokin storm respons pathophysiolog covid infect present studi investig potenti isol compound clerodendrum volubil leav stall oxid burst vitro interact orf mrna segment sar cov whole genom use comput tool five compound name harpagid methyl butenoxi propenyl benzen ajugosid iridoid glycosid eruc acid isol c volubil leav structur elucid use convent spectroscopi tool iridoid glycosid report first time thus regard new compound orf mrna sequenc translat initi site tis translat termin site ttss encod orf amino acid retriev full genom sar cov molecular dock studi reveal strong molecular interact isol compound tis tts orf mrna harpagid show strongest bind affin tis eruc acid strongest tts immunomodulatori potenti isol compound investig neutrophil phagocyt respiratori burst use luminol amplifi chemiluminesc techniqu compound signific inhibit oxid burst methyl butenoxi propenyl benzen best activ ajugosid eruc acid show signific inhibitori activ cell prolifer result indic potenti c volubil compound immunomodul util curb cytokin storm implic covid infect potenti corrobor strong interact compound tis tts orf mrna sar cov whole genom | D000086382;D032409 | T047;T002;T067 |
34,688,169 | evalu cardiopulmonari system outcom children development coordin disord systemat review children development coordin disord dcd tend avoid physic activ affect health well | D019957 | T048 |
34,688,168 | non alcohol fatti liver diseas current therapeut option nonalcohol fatti liver diseas nafld common caus chronic liver diseas estim global preval nafld found peopl obes patient diabet cardiovascular diseas main caus mortal follow extra hepat cancer liver specif complic cirrhosi hepatocellular carcinoma lifestyl modif remain primari intervent nafld weight loss achiev dietari modif exercis lead histolog improv revers metabol complic current drug therapi limit pioglitazon vitamin e howev sever agent current phase iii develop review summaris current treatment option nafld | D065626 | T047 |
34,688,167 | preval antimicrobi resist campylobact wild bird prey spain wild bird identifi relev reservoir campylobact spp therefor potenti sourc infect human domest anim object studi determin occurr campylobact spp bird prey spain addit antibiot resist profil isol evalu total specimen raptor speci analyz result individu preval c jejuni frequent isol speci follow c coli c lari occurr campylobact signific higher p nocturn bird prey spring season carnivor speci isol display remark resist nalidix acid ciprofloxacin tetracyclin low resist streptomycin find highlight import bird prey reservoir campylobact strain signific role carrier antimicrobi resist | D002167;D002169;D017000;D016123;D020304 | T007;T047;T012 |
34,688,166 | cannabi use disord dissoci report prospect first episod psychosi studi cannabi use recreat drug worldwid use increas risk develop psychot disord exacerb cours howev relationship cannabi use dissoci symptom scarc investig | D014150;D002188;D002189;D011618 | T047;T121;T002;T109;T167;T039;T048 |
34,688,165 | global local hyper local model accur forecast covid assumpt well mix popul model often erron made without due analysi valid ignor import geo spatial granular data collect could signific implic qualiti forecast action clinic recommend base | D000086382 | T047;T067 |
34,688,163 | molecular simul probe potenc resveratrol regul toxic aggreg mutant vm ttr fibril transthyretin mediat amyloidosi transthyretin ttr mediat amyloidosi high ruinous ill affect various organ aggrav deposit misfold mutat ttr protein aggreg tissu henc hinder format ttr amyloid aggreg could key strategi find effect cure toward aggrav disord analysi examin subvers natur point mutat vm ttr promot amyloidogen use discret molecular dynam dmd simul besid probe associ natur occur polyphenol egcg proven anti ttr aggreg agent posit control resveratrol curcumin mitig pathogen repercuss mutant ttr result comput studi endors resveratrol constitut restor potenti subjug ttr mediat amyloidosi besid egcg henc studi could reminisc aspect understand inhibitori role key polyphenol mutant ttr aggreg could aid toward structur base drug design upcom research era famili amyloid disord | D000686;D011228 | T116;T047;T123 |
34,688,162 | dft investig effect dope electron structur electrochem activ pyrit fes pyrit fes semiconductor miner electron structur properti heavili influenc trace element composit demonstr experiment reduct fe ion signific enhanc presenc trace arsenic atom fes use densiti function theori calcul compar geometr electron structur properti pure dope pyrit surfac interact fe ion common oxid sulfid acid solut acid mine drainag aforement surfac thorough investig find reveal addit atom alter electron structur pyrit decreas band gap adsorpt energi fe ion dope pyrit greater pure pyrit calcul gibb free energi chang show reduct fe fe ion modifi surfac thermodynam favor pure pyrit | D001151 | T131;T121;T196 |
34,688,161 | optim coval dock organophosph interact anophel acetylcholinesteras organophosph op use potent insecticid malaria vector control coval phosphoryl catalyt serin residu anophel gambia ach agach reaction liber leav group recent year insecticid use assess op frequent use world health organ prequalifi insecticid molecular model program best suit display molecular interact ligand target protein dock mode generat ligand pose closer bind site show high accuraci predict ligand bind mode implicit solvat approach molecular mechan general born surfac area mm gbsa reliabl method predict ligand onform bind affin apart coval dock studi scarc current molecular dock program adequ possess coval dock reaction algorithm display molecular mechan op agach catalyt site result op dock studi common conduct noncoval pannel aim studi establish optimim coval dock system op manual custom schrdinger glide coval dock reaction algorithm achiev newli custom coval reaction algorithm assess set ligand cover aromat non aromat hydrophob op compar noncoval dock result term reliabl base report x ray diffract molecular interact crystal pose studi establish virtu omit well known op hydrolysi noncoval mode suggest molecular interact catalyt triad could otherwis occur molecul hydrolyz custom coval dock mode moreov mm gbsa concur optim coval dock elimin inaccur molecular interact addit coval dock mode confin interact ligand pose catalyt site indic relat high accuraci reliabl studi report optim coval dock panel effect confirm molecular mechan op well indentifi correspond amino acid residu requir stabil aromat non aromat hydrophob op agach catalyt site line report x ray diffract studi propos manual custom schrdinger glide coval dock platform use reliabl predict molecular interact op agach target | D000852;D008288 | T204;T047 |
34,688,160 | predict novel drug candid covid use generat deep neural network novel coronavirus outbreak creat massiv econom crisi mani succumb death disturb live mankind world current viabl treatment condit drug develop approach pursu vigor major treatment option repurpos exist drug find new one tradit method drug discoveri take longer time urgent need develop altern techniqu reduc search space drug candid toward endeavor propos novel drug discoveri method leverag long short term memori lstm model generat novel molecul adept bind novel coronavirus proteas studi demonstr propos method abl recreat novel molecul correl much properti train molecul fine tune model generat novel drug like molecul activ toward specif target consid clpro main proteas novel coronavirus therapeut target demonstr silico screen assess target structur bind affin dock simul observ generat molecul show dock free energi less kcalmol top generat drug candid highest bind affin dock score kcalmol much lower compar approv exist commerci drug includ remdesivir low bind energi indic generat molecul could explor potenti drug candid covid | D000086382;D004364 | T047;T121;T067 |
34,688,159 | evalu medic malpractic claim obstetr ultrasonographi opinion council forens medicin turkey council forens medicin institut affili ministri justic republ turkey act offici oversight capac case alleg medic malpractic forens medic scienc sonograph may face judici sanction result ultrasonographi examin perform accord current guidelin studi focus attent claim medic malpractic relat obstetr ultrasonographi refer council forens medicin aim investig caus malpractic claim relat obstetr ultrasonographi present expert opinion council claim light literatur also plan discuss done current guidelin inform prevent situat caus malpractic claim | D008318 | T080 |
34,688,158 | ankl brachial index subsequ risk incid recurr cardiovascular event older adult atherosclerosi risk communiti aric studi ankl brachial index abi diagnost test screen detect peripher arteri diseas pad well risk enhanc ahaacc guidelin primari prevent atherosclerot cardiovascular diseas ascvd howev understand associ abi cardiovascular risk contemporari older popul limit addit prognost valu abi among individu prior ascvd well understood | D050197;D003327;D058729 | T047;T046 |
34,688,157 | sulfid quinon oxidoreductas requir cystein synthesi indispens mitochondri health mitochondri dysfunct relat common age relat disord includ neurodegen diseas metabol syndrom carcinogenesi therefor maintain function integr mitochondria import human health herein found sulfid quinon oxidoreductas sqr oxid hydrogen sulfid reactiv sulfur speci rss indispens mitochondria health eukaryot model microorgan schizosaccharomyc pomb sqr knock led morpholog chang function defici mitochondria apoptosi pomb sqr knock strain display phenotyp cystein synthesi defici strain cystein addit complement effect caus sqr knock pomb sqr main rss produc mitochondria rss instead h use cystein synthas synthes cystein find rewrit cystein biosynthesi rout pomb may also eukaryot prokaryot highlight import cystein rss maintain mitochondri health | D006862;D011808 | T116;T130;T131;T197;T126 |
34,688,156 | non canon effect heme oxygenas classic fighter oxid stress role heme oxygenas resist oxid stress cell protect alway hot research topic continu deepen research addit direct regul redox catalyz degrad heme ho protein also particip gene express level great divers method therebi initi cell defens particular non canon nuclear local ho ho protein interact play role warrior oxid stress besid ho may promis marker diseas predict detect mani clinic trial especi malign diseas may new advanc treatment ho regul abnorm ros metabol signal purpos review systemat sort describ sever aspect research facilit detail mechan research clinic applic promot futur | D006419;D051547 | T116;T126 |
34,688,151 | compar outcom treatment inf interferon beta ifn b interferon beta b among covid inpati ifn known one promis drug use covid treatment studi aim investig effect treatment inf interferon beta ifn b interferon beta b covid inpati | D000086402 | T005 |
34,688,149 | triumvir nf b inflamm cytokin storm covid coronavirus diseas covid remind us signific host immun respons consequenti havoc immun dysregul sever acut respiratori syndrom coronavirus sar cov inflict sever complic infect host includ cough dyspnoea fever septic shock acut respiratori distress syndrom ard multipl organ failur manifest consequ dysregul immun system give rise excess unattend product pro inflammatori mediat elev circulatori cytokin chemokin level accompani spontan haemorrhag thrombocytopenia system inflamm cardin featur life threaten cytokin storm syndrom advanc covid diseas coronavirus hijack nf kappa b nf b respons upregul express inflammatori cytokin chemokin alarmin induc enzym pave pathway cytokin storm given scenario system approach simultan inhibit nf b offer attract therapeut intervent target therapi proteasom inhibitor vl bortezomib carfilzomib ixazomib bruton tyrosin kinas inhibitor acalabrutinib nucleotid analogu remdesivir tnf monoclon antibodi infliximab adalimumab n acetylcystein corticosteroid dexamethason focus nf b inhibit demonstr effect term signific decreas morbid mortal sever covid patient henc review highlight activ signal transduct cross talk nf b regard cytokin storm covid moreov develop therapeut strategi base nf b inhibit also discuss herein | D000086402 | T005 |
34,688,148 | chemiluminesc determin vancomycin use nis nanoparticl luminol system research nis nanoparticl nps produc use hydrotherm techniqu character sever spectroscop method first time shown nis nps could exploit nanocatalyst chemiluminesc cl reaction introduc nis nps could intensifi luminol cl reaction remark besid shown vancomycin van suppress cl intens nis nps luminol reaction exploit result obtain new straightforward cl method develop measur van linear concentr rang cl method mol l limit detect lod equal mol l relat standard deviat rsd cl method n determin mol l van establish cl method appli quantifi van inject spike human serum | D008165;D053758 | T130;T073;T109 |
34,688,147 | model experiment investig small scale gasif chp unit enhanc use local biowast small scale gasif combin heat power system fed biowast resourc potenti enhanc local renew energi product reduc carbon emiss address challeng wast dispos howev lack understand influenc challeng feedstock exampl digest poultri litter municip solid wast synga qualiti incid dri stage overal process paper address gap analys compar sampl common biowast feedstock develop stoichiometr thermodynam one stage equilibrium model experiment valid calibr laboratori result maximum error real predict valu simul result show low heat valu synga produc biowast resourc analys rang mjnm dri basi work optim equival ratio increas electr thermal output achiev feedstock moistur content dri process may requir heat produc furthermor result show downdraft gasif base combin heat power feasibl interest option deal biowast resourc potenti avoid cost risk extern landfil contribut increas local electr heat product renew energi sourc grid grid applic | D012037 | T057 |
34,688,146 | effect dental restor geometri materi properti biomechan behaviour treat molar tooth finit element analysi test hypothesi restor class ii mesio occlus distal mod caviti strengthen judici choic restor geometri materi properti | D020342 | T170 |
34,688,144 | corticospin tract abnorm ventricular dilat transdiagnost compar tractographi studi microstructur alter corticospin tract cst found idiopath normal pressur hydrocephalus inph studi howev investig effect ventricular dilat cst progress supranuclear palsi psp | D011712;D013494 | T047;T023 |
34,688,143 | multipl brain system dynam interact tonic phasic state support languag integr tempor lobe epilepsi epileptogen focus domin tempor lobe result reorgan languag system order compens compromis function studi compensatori reorgan languag set left tempor lobe epilepsi tle take account interact languag l key non languag nl network dorsal attent dan fronto pariet fpn cingulo opercular copn system provid cognit resourc help success languag perform appli tool dynam network neurosci function mri data collect tle patient match healthi control rest state rs sentenc complet sc task captur function architectur languag network dynam chang interact nl system two context provid evid brain area core languag function resid dynam interact non languag function network carri linguist function demonstr abnorm integr languag dan exist tle present tonic well phasic state integr consid reflect entrain visual attent system system dedic lexic semant process data made clear level baselin integr languag subsystem certain nl system eg dan fpn crucial influenc general level task integr lnl system normat find uniqu epilepsi also reveal broad set task lnl integr tle predict languag compet indic integr compensatori patient lower overal languag skill conclud rs establish broad set lnl integr avail prime use task actual use interact set tle depend level languag skill believ analys first captur potenti compensatori role play dynam network reconfigur multipl brain system perform complex languag task addit test characterist phasictask tonicrest state necessari achiev languag compet set tempor lobe patholog analys highlight intra versus inter system communic form basi uniqu languag process tle point dynam reconfigur provid broad multi system support need maintain languag skill compet | D004833 | T047 |
34,688,141 | combin ultrasound chlorogen acid inactiv staphylococcus aureus plankton biofilm food system studi aim investig mechan differ treatment name ultrasound us chlorogen acid ca ultrasound combin chlorogen acid us plus ca inactiv staphylococcus aureus plankton biofilm cell result show combin treatment us ca exhibit remark synergist antibacteri antibiofilm effect scan electron microscopi imag indic combin treatment us ca caus serious damag cell morpholog confoc laser scan microscopi imag reveal combin treatment led sharp increas sever damag permeabl cell membran caus releas atp nucleic acid decreas exopolysaccharid content aureus biofilm final combin treatment us plus ca min inactiv aureus cell lg cfug mutton thus combin treatment us ca synergist effect aureus plankton biofilm food system | D010933;D013211 | T204;T007 |
34,688,140 | tempor exposur malathion biochem chang amazonian fish tambaqui colossoma macropomum main toxic mechan organophosph insecticid malathion acetylcholinesteras enzym inhibit howev fish respons organophosph may vari depend activ differ defens mechan well length exposur evalu acetylcholinesteras activ combin evalu biotransform antioxid enzym level use indic damag fish expos insecticid moreov evalu mitochondri activ might evid hierarch respons occur relat length time fish expos therefor aim studi evalu whether length exposur malathion differenti affect biochem respons tambaqui hypothesi physiolog alter due exposur time depend fish expos subleth concentr insecticid h contrari expect acetylcholinesteras activ inhibit experi indic absenc neurotox phase ii biotransform mechan activ earli especi liver oxid damag evid first hour exposur concurr activ antioxid enzym mitochondri bioenerget differenti affect length exposur data suggest tambaqui regul mitochondri respir differ time seek maintain homeostasi atp demand ensur activ respons mechan thus minim oxid damag avoid neurotox malathion | D060125;D007306;D014874 | T131;T013 |
34,688,139 | metabol cytotox diphenylarsin acid degrad product sea dump chemic warfar agent rainbow trout liver cell line rtl w recent studi found primari degrad product phenylarsen chemic warfar agent cwas accumul fish tissu potenti effect dump phenylarsen cwas clark ii baltic sea biota poor understood studi metabol cytotox diphenylarsin acid dpa primari degrad product phenylarsen cwa studi incub rainbow trout cell line rtl w cell media mgl dpa previous undescrib metabolit identifi ultra high perform liquid chromatographi high resolut mass spectrometri uphlchrm moreov cytotox diphenylarsin glutathion conjug dpa sg major metabolit dpa studi cytotox compound evalu use neutral red retent test nrr show ic valu mgl dpa mgl dpa sg indic glutathion gsh conjug dpa two order magnitud toxic dpa suggest toxic properti dpa increas conjug intracellular gsh lead enhanc toxic uptak result gain studi give detail inform elucid biolog effect dump chemic munit marin environ moreov result help assess environment health risk pose marin munit continu presenc deterior sea bottom | D002619;D017686;D014874 | T131;T013 |
34,688,138 | critic role mitochondri altern chain juvenil ark shell anadara broughtonii expos acut hypoxia without sulfid reduc oxygen level increas sulfid concentr becom concern marin anim studi examin respiratori energet adapt acut h hypoxia mgl dissolv oxygen without sulfid mm mm mm hypoxia resist sulfid toler ark shell anadara broughtonii differ state aerob respir energi balanc activ mitochondri sulfid oxid chain msoc condit evalu result indic anaerob pathway activ hypoxia h without sulfid activ presenc sulfid h exposur sulfid result signific accumul atp probabl due activ msoc lower metabol via suppress na k atpas activ protein synthesi hypoxia enzym activ mrna level altern oxidas aox increas key enzym msoc sulfid quinon oxidoreductas sqr sulfur dioxygenas sdo alter addit sulfid enzym activ mrna level aox sqr sdo signific increas classic aerob respir signific inhibit induct altern respir detect correspond altern electron transport chain aetc accept electron origin tricarboxyl acid cycl msoc challeng indic capac aerob respir sulfid oxid reduct state might great depend aetc synergist induc altern chain aetc msoc anaerob pathway suggest energi balanc respir sulfid oxid might contribut endur ark shell acut sulfid exposur | D049893;D011808;D014874 | T131;T204;T116;T126 |
34,688,133 | histopatholog character peri implant diseas systemat review meta analysi conduct systemat review inflammatori element peri implant pi peri implant mucos pm comparison healthi peri implant tissu hi periodont diseas | D055113;D015921;D057873 | T074;T047 |
34,688,132 | periodont ligament fibroblast deriv exosom induc compress forc promot macrophag polar via yes associ protein studi aim investig biolog role mechan compress forc stimul periodont ligament fibroblast pdlfs polar macrophag design pdlfs stimul without static compress forc condit medium high molecular weight protein low molecular weight protein collect treat thp macrophag rt qpcr flow cytometr analysi use evalu polar macrophag exosom isol ultracentrifug method identifi via transmiss electron microscopi western blot nano track analysi protein level yes associ protein yap contain exosom detect western blot gw verteporfin use inhibit exosom secret yap tea domain transcript factor tead interact respect | D055354 | T026 |
34,688,126 | human genet polymorph risk viral infect solid organ transplant immun system play key role host defens viral pathogen signal cascad activ upon infect involv varieti molecul pattern recognit receptor prrs interleukin antivir interferon long term immunosuppress solid organ transplant sot main abrog adapt cell mediat respons thus highlight relat contribut innat immun singl nucleotid polymorph snps within gene code prrs solubl mediat associ differenti suscept viral infect among sot recipi protect effect cytomegalovirus cmv infect diseas attribut certain snps tlr ifnl gene wherea opposit effect attribut genet polymorph tlr mbl dc sign il ifng presenc snps molecul direct involv innat adapt immun respons aquaporin pregnan x appear modul risk cmv bk polyomavirus infect respect littl inform avail genet determin post transplant suscept herpesvirus caus clinic infect herp simplex virus varicella zoster virus replic kinet compon human blood virom use immun surrog torqu teno virus present review critic summar current knowledg snp genotyp would use stratifi sot recipi accord individu risk viral infect propos next research step genet suscept test may improv person medicin contribut minim risk viral infect sot | D003586;D006561;D037601;D016377;D020641 | T116;T047;T121;T061;T086 |
34,688,125 | first report two foodborn salmonella enterica subsp enterica serovar bovismorbifican isol carri novel mega plasmid harbor bla dha qnrb gene salmonella enterica display resist extend spectrum cephalosporin fluoroquinolon fqs deem high prioriti pathogen world health organ ctx type acquir lactamas detect enterica serovar bovismorbifican dha enzym rare report bovismorbifican studi report first time isol two multi drug resist mdr bovismorbifican strain co harbor plasmid encod ampc pampc lactamas gene bla dha qnrb gene sal isol chicken meat sampl sal grass carp fish sampl collect retail market guangzhou china bla dha qnrb gene two strain locat novel bp inchi plasmid belong st plasmid contain addit acquir antimicrobi resist gene encod resist eight antibiot class quaternari ammonium compound besid sal contain addit bp col phad like plasmid harbor qnrs bla dha qnrb gene locat bp region sul qace ampr bla dha pspabcdf qnrb sapabc sul qace identifi various bacteria speci indic high transfer abil bla dha qnrb gene within gene cluster inchi plasmid found transfer escherichia coli j conjug result acquir multipl resist transconjug genom sequenc comparison cgmlst mauv align indic sal sal high similar epidemiolog link strain sourc countri find suggest bovismorbifican new host conjug mega plasmid harbor bla dha qnrb gene highlight potenti transmiss opportun bovismorbifican clone food chain need continu investig | D012475;D019779 | T007 |
34,688,124 | use nanoencapsul curcumin veget cell spore alicyclobacillus spp industri orang juic pathogen deterior bacteria great concern food safeti sens present studi evalu fight microbi contamin use nanoparticl contain curcumin addit analyz physic properti nanoparticl effici curcumin encapsul determin fourier transform infrar spectra evalu differenti scan calorimetri transmiss electron microscopi imag show irregular shape nanoparticl broad size distribut nm antibacteri activ consid satisfactori sinc curcumin form nanoparticl demonstr antimicrobi antibacteri activ superior curcumin free form pathogen bacteria staphylococcus aureus mic gml deterior alicyclobacillus acidoterrestri mic gml sinc curcumin nanoparticl may consum food addit bioactiv properti nanoencapsul curcumin also evalu relat antioxid capac thiobarbitur acid reactiv substanc tbar oxid hemolysi inhibit assay cytotox four carcinoma cell line well two non tumor cell proof concept nanoparticl incorpor orang juic juic maintain satisfactori ph brix color stabil three day storag c | D056450;D032084;D003474 | T007;T121;T002;T109;T130;T168 |
34,688,122 | desir think questionnair persian version dtq p associ addict behavior individu alcohol use disord nicotin depend problemat social media use desir think emerg construct shown play role addict behavior present studi sought valid translat persian version desir think questionnair dtq three group individu alcohol use disord aud n nicotin depend n problemat social media use n three group complet translat persian version dtq barratt impuls scale bis white bear suppress inventori wbsi depress anxieti stress scale dass measur alcohol use nicotin depend problemat social media use also collect result confirm two factor structur persian version dtq good reliabl valid three group furthermor verbal persever imagin prefigur compon persian version dtq found predict addict behavior beyond demograph clinic characterist negat affect impuls thought suppress studi confirm psychometr properti persian version dtq role desir think independ predictor aud nicotin depend problemat use social media | D000437;D016739;D061108;D014029 | T048;T170 |
34,688,121 | associ depress oral health relat qualiti life peopl inject drug oral health relat qualiti life ohrqol known reduc disadvantag popul includ peopl inject drug mental health issu depress also common report studi examin associ depress ohrqol | D055030;D011788 | T033;T101;T098;T078 |
34,688,120 | develop valid discomfort cloth mask dcm scale covid pandem use face mask public help slow spread sever acut respiratori syndrom coronavirus sar cov communiti cloth mask recommend effect avail reusabl like type face mask howev user discomfort wear cloth mask thought engend behavior limit effect cloth mask sourc control eg adjust remov one mask temporarili public design cloth mask toler measur instrument assess subject user discomfort need across two studi identifi confirm two dimension factor structur under discomfort cloth mask discomfort relat breathabl discomfort relat tight mask face head addit provid replic evid factor subscal predict self report frequenc problemat mask wear behavior | D000086382;D008397 | T074;T047;T067 |
34,688,119 | understand trauma experi need comprehens assess transit age youth child welfar context child welfar transit age youth tay high rate trauma experi tes like exhibit negat outcom transit adulthood | D002669;D005190 | T079;T099;T054;T058;T062 |
34,688,118 | neighborhood greenspac cardiometabol risk factor cross section longitudin analysi elsa brasil particip greater neighborhood greenspac associ better cardiometabol risk factor especi high incom countri cross section longitudin studi assess associ approxim particip brazilian longitudin studi adult health elsa brasil resid belo horizont larg brazilian capit citi neighborhood greenspac studi normal differ veget index ndvi two addit type percentag tree cover herbac cover multivari logist regress model estim cross section longitudin associ neighborhood greenspac three metabol factor obes ii abdomin obes iii low hdl cholesterol adjust individu sociodemograph factor neighborhood averag household incom per capita cross section result show higher neighborhood greenspac associ lower odd obes abdomin obes low hdl c howev neighborhood greenspac associ incid risk factor percentag tree cover seem contribut associ found ndvi percentag herbac cover result support evid increas neighborhood greenspac contribut maintain better cardiometabol health | D002318;D000068316 | T047;T083 |
34,688,117 | readi name chang schizophrenia survey multipl stakehold one peopl worldwid diagnos schizophrenia mani peopl advoc name chang condit point stigma discrimin associ term schizophrenia well name poor character featur ill purpos project collect opinion broad divers sampl stakehold possibl name chang schizophrenia project repres partnership research clinician live experi psychosi group develop survey assess opinion need chang name schizophrenia well potenti altern name accumul respons broad array communiti stakehold includ live experi mental ill famili member clinician research govern offici general public find indic major respond favor name chang schizophrenia found name stigmat propos altern name support includ alter percept syndrom psychosi spectrum syndrom neuro emot integr disord survey find provid strong support renam schizophrenia express hope name chang reduc stigma discrimin | D012559 | T048 |
34,688,116 | socioemot mechan loneli subclin psychosi loneli import predictor physic mental health general popul individu across psychosi spectrum includ experienc subclin psychot like experi ples howev mechan under loneli psychosi spectrum well understood emot process deficit well describ across psychosi spectrum socioemot process bias critic develop mainten loneli alter social apprais includ judgement reject therefor propos ples associ increas loneli relationship mediat alter socioemot process also explor pathway may affect mood anxieti symptom associ loneli across psychosi spectrum part human connectom project general healthi adult n report symptomatolog social function complet penn emot recognit task assess effici identifi emot found higher report ples associ elev level loneli perceiv reject factor link multipl independ pathway first anxietydepress emot process effici independ mediat ple loneli relationship second found associ ples loneli serial mediat ineffici emot recognit higher level perceiv reject separ mechan increas loneli subclin psychosi implic treatment continu studi social function psychosi spectrum | D008132;D011618 | T033;T048 |
34,688,115 | high polymorph panel plex microhaplotyp chines han popul applic estim number contributor dna mixtur microhaplotyp mhs great potenti multipl forens applic proven promis marker complex dna mixtur analysi studi develop multiplex panel high polymorph mhs chines han popul evalu forens valu explor applic predict number contributor noc dna mixtur panel consist newli propos loci previous report loci length span less bp averag effect number allel e cumul match probabl cmp cumul power exclus cpe reach e e respect chines han popul genom project valid chines han individu show e rang mean valu cmp cpe e e respect indic panel inform person identif patern test studi popul estim noc dna mixtur develop machin learn model base panel result accuraci artifici dna mixtur reach person mixtur person mixtur furthermor noc estim simul profil allel dropout show panel still robust slight dropout conclus panel valu forens identif noc estim dna mixtur | D016172;D020641 | T086;T034;T063 |
34,688,114 | use multi head convolut neural network data augment improv electropherogram classif perform dna profil generat forens biolog laboratori around world possibl profil assess two independ peopl order profil read recent work carri develop neural network model classifi fluoresc dna profil electropherogram potenti replac one human reader abil use neural network function program softwar fastr dna valid use least one laboratori australia work previous develop neural network system number limit specif comput intens make best use avail data consequ perform model sub optim condit particular low intens peak current work new neural network model develop make various improv old model use convolut layer multi head architectur data augment result indic improv perform expect low intens profil | D016571;D012984 | T170;T073;T090 |
34,688,113 | beyond liquid biopsi toward non invas assay distanc cancer diagnost pandem liquid biopsi technolog seen signific improv last decad offer possibl reliabl analysi diagnosi sever biolog fluid use technolog overcom limit standard clinic method relat invas poor patient complianc along matur exampl lab chip loc avail could emerg breakthrough technolog present near futur clinic demand provid sampl treatment reagent addit analysi sampl inansw approach possibl combin non invas liquid biopsi loc technolog could great assist current need minim exposur transmiss risk recent ongo pandem outbreak sar cov inde heavili influenc aspect life worldwid ordinari task forc switch presenc distanc limit possibl larg number activ field life outsid home unfortun one set physic distanc assum noteworthi consequ screen diagnosi follow diseas review analys biolog fluid easili collect without intervent special personnel possibl may use innov diagnost assay consid advantag limit main due stabil storag integr point care diagnost demonstr technolog case matur enough meet current clinic need | D015374;D000086382;D009369 | T191;T047;T075;T067;T059 |
34,688,112 | rapid accur clinic test covid nick extens chain reaction system base amplif nesba herein describ rapid accur clinic test covid nick extens chain reaction system base amplif nesba ultrasensit version nasba primer identifi sar cov viral rna design addit contain nick recognit sequenc end convent nasba primer would enabl nick enzym aid exponenti amplif rna promot contain doubl strand dna tdna consequ substanti enhanc amplif power nesba techniqu abl ultrasensit detect sar cov genom rna grna copiesl copiesreact envelop e nucleocapsid n gene within min isotherm temperatur c nesba appli test larg cohort clinic sampl n result fulli agre qrt pcr show excel accuraci yield clinic sensit specif employ multipl molecular beacon differ fluorophor label nesba modul achiev multiplex molecular diagnost e n gene sar cov grna simultan assay one pot offer superior analyt perform current qrt pcr isotherm nesba techniqu could serv power platform technolog realiz point care poc diagnosi covid | D015374;D000086382 | T047;T059;T067;T075 |
34,688,111 | dual confin high load enzym within metal organ framework glucos sensor enhanc cascad biocatalysi intrins fragil natur leakag enzym major obstacl commerci sensor continu glucos monitor system herein dual confin effect develop three dimension nanocag base zeolit imidazol framework nc zif high load enzym well encapsul unusu bioactiv stabil shell nc zif set first confin prevent enzym leakag interior nanocag nc zif provid second confin immobil enzym offer spacious environ maintain conform freedom moreov mesoporos form nc zif precis control effect enhanc mass transport result goxhemin nc zif multi enzym system could realiz rapid detect glucos colorimetr electrochem sensor high catalyt cascad activ fold fold enhanc comparison free enzym solut respect also exhibit long term stabil excel select reusabl import base wearabl sweatband sensor measur result show high correl p level measur commerci glucomet report dual confin strategi open window immobil enzym enhanc catalyt effici stabil clinic grade noninvas continu glucos sensor | D015374;D000073396 | T059;T109;T075 |
34,688,110 | dual fiber optic bioprob system triglycerid detect use surfac plasmon reson sens lipas immobil magnet bead hydrolysi rapid accur detect triglycerid tg play valuabl role prevent control dyslipidemia paper novel method tg detect use dual fiber optic bioprob system accur detect differ level tg concentr serum propos system employ dispos microprob type fiber optic surfac plasmon reson spr biosensor signal acquisit provid high stabil portabl avoid cross contamin caus repeat use propos biosensor high sensit nm mgml tg detect serum tini diamet fabric use novel multimod fiber singl mode fiber reflector msr structur scarc ever report best knowledg process tg detect lipas immobil magnet bead introduc specif hydrolyz tg relationship tg content spr differenti signal obtain dual fiber optic bioprob measur tg sampl hydrolysi propos method achiev tg detect concentr rang mgml includ healthi unhealthi level tg concentr human bodi addit miniatur fiber optic biosensor use work advantag low sampl consumpt high sensit simpl oper label free measur high select low cost method provid new pathway rapid reliabl tg detect potenti applic medic research clinic diagnosi | D015374;D020349 | T059;T063;T075 |
34,688,109 | effect eccentr linear radial speed bias test motion depth model radial motion perceiv faster linear motion local spatiotempor properti match radial speed bias rsb thought occur radial motion part interpret motion depth geometri dictat fix amount radial expans increas eccentr consist smaller motion depth perhap surpris impact eccentr rsb examin issu mind across experi investig rsb function eccentr ifc task particip judg linear test variabl speed radial refer stimulus appear move faster linear radial stimuli compris gabor patch arrang left right fixat vari eccentr linear stimuli gabor drift left right wherea radial stimuli gabor drift toward away centr rsb differ perceiv speed match linear radial stimuli recov fit psychometr function across experi found rsb decreas eccentr tendenc less mark beyond ie odd geometri effect continu decreas function eccentr true irrespect whether stimuli fix size experi vari size account chang spatial scale across retina experi also true remov conflict stereo cue via monocular view experi investig data extend previous model speed percept suggest perceiv motion stimuli reflect balanc two oppos perceptu interpret one motion depth object deform propos context model data consist place greater weight motion depth interpret increas eccentr rsb continu reduc line pure geometr constraint | D009039 | T041 |
34,688,108 | impact heat wave cold spell caus specif mortal citi paulo brazil impact heat wave cold spell mortal becom major public health problem worldwid especi among older adult live low middl incom countri studi aim investig effect heat wave cold spell differ definit caus specif mortal among peopl age year paulo quasi poisson general linear model distribut lag model use investig associ caus specif mortal extrem air temperatur event evalu effect intens differ durat consid twelv heat wave nine cold spell definit result show increas caus specif death relat heat wave cold spell sever definit highest risk death relat heat wave identifi most higher temperatur threshold longer event verifi men vulner die cerebrovascular diseas ischem stroke cold spell heat wave day women women present higher risk die ischem heart diseas cold spell tend higher risk chronic obstruct pulmonari diseas men heat wave identif heat wave cold spell relat mortal import develop promot public health measur | D003080;D006358 | T070 |
34,688,107 | drive influenc hallucinogen preval correl risk profil hallucinogen use rise us yet littl known regard preval psychosocialbehavior correl drive influenc drug | D001334;D002188;D000066448;D006213;D013287;D019966 | T121;T002;T056;T109;T167;T055;T131;T048;T033 |
34,688,106 | long term opioid therapi taper trend midwestern state center diseas control prevent guidelin prescrib opioid chronic pain guidelin hereaft emphas taper patient long term opioid therapi ltot harm outweigh benefit | D000701;D059350 | T047;T121;T184;T109;T131 |
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