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34,688,634
supersensit photon upconvers base immunoassay detect cardiac troponin human plasma upconvert nanoparticl ucnp attract report immunoassay due excel detect assay sensit enough measur baselin level cardiac troponin ctni healthi popul could use identifi patient risk cardiovascular diseas aim ctni assay sensit surfac chemistri nanoparticl well assay reagent protocol optim monodispers ucnp antibodi conjug mab ucnp minim non specif interact solid support
D053758;D019210
T116;T073;T123
34,688,633
elut independ collect devic eicd rapid collect anaplasma marginal dna blood sampl current util molecular detect method base main nucleic acid extract amplif detect procedur may requir cost equip numer reagent high train personnel requir make diagnost test expens time consum suitabl point care applic increas demand simpl low cost portabl technolog overcom challeng paper base elut independ collect devic eicd design collect microorgan recov nucleic acid molecular biolog applic minim step studi demonstr simpler anaplasma marginal detect use eicd nucleic acid collect combin recombinas polymeras amplif rpa later flow dipstick detect specifi target pre lysi blood treatment optim use triton x lysi buffer bovin serum album wash buffer blood sampl incub min room temperatur run eicd four mm diamet disc excis eicd use templat basic rpa later flow nfo endonucleas iv rpa assay disc solubl central membran scm carri circa pgl anaplasma dna percentag nucleic acid recover scm rang blood sampl infect marginal treat triton x pre lysi protocol sampl test posit pcr rpa method eicd driven collect blood sampl practic method success adapt detect anaplasma spp blood born pathogen dna potenti point care detect resourc limit set
D042322
T007
34,688,632
preval spatial heterogen trichomona vaginali infect among femal popul associ climat guangxi zhuang autonom region southern china two cervic cancer screen ccs project ongo year guangxi zhuang autonom region guangxi trichomona vaginali infect tvi case found opportunist find studi aim identifi high risk popul expound spatial epidemiolog featur tvi guangxi
D014246;D002583
T204;T191
34,688,631
combin carvacrol albendazol enhanc efficaci monotherapi experiment alveolar echinococcosi alveolar echinococcosi helminth zoonosi caus larval stage echinococcus multiloculari surgic resect parasit feasibl pharmacolog treatment albendazol option due difficulti achiev success treatment necessari find new drug improv treatment diseas present work efficaci carvacrol alon combin albendazol evalu e multiloculari metacestod associ carvacrol albendazol produc greater vitro effect compound incub separ effect treatment combin gml carvacrol gml albendazol clinic efficaci studi treatment infect mice carvacrol mgkg albendazol mgkg reduc weight metacestod respect combin drug efficaci result coincid tissu damag observ ultrastructur level conclus carvacrol albendazol combin enhanc efficaci monotherapi strategi would allow improv efficaci treatment without increas dose albendazol lengthen treatment period reduc occurr advers effect
D000871;D004443;D048210
T204;T047;T121
34,688,630
molecular detect genotyp divers hemoplasma non hematophag bat associ ectoparasit sampl peri urban area brazil hemoplasma alreadi detect bat unit state america spain australia chile brazil peru beliz nigeria costa rica germani switzerland new caledonia recent detect hemoplasma close relat mycoplasma haematohomini agent caus diseas human emphas need addit studi divers hemoplasma bat present work aim investig occurr assess phylogenet posit genet divers hemoplasma bat associ ectoparasit sampl central western brazil overal sampl bat bat fli megistopoda aranea posit hemoplasma howev twenti four two hemoplasma sequenc obtain pcr assay target rrna gene respect sinc major obtain amplicon show faint band agaros gel electrophoresi obtain rrna sequenc show broad distribut along phylogenet tree albeit posit within haemof group cluster bat associ hemoplasma twelv rrna hemoplasma genotyp found among obtain sequenc compar bat relat hemoplasma sequenc retriev genbank genotyp found two rrna sequenc obtain posit sister clade candidatus mycoplasma haematohydrochaerus haemof haemocani high genet divers found among rrna hemoplasma sequenc detect non hematophag bat central western brazil previous detect region world even though genotyp analysi show hemoplasma genus tend group togeth result unipartit bipartit analys robust support hypothesi studi address specif hemoplasma genotyp accord bat speci genera perform
D009175
T047
34,688,629
toxoplasma gondii activ nlrp inflammasom pathway balbc murin model host resist toxoplasma gondii gondii infect relat initi immun respons studi aim investig role leucin rich repeat famili pyrin domain contain protein nlrp cytoplasm nucleotid bind domain inflammasom mediat cell death murin toxoplasmosi group balbc mice n inocul intraperiton live tachyzoit excretori secretori antigen esa gondii rh strain rpmi gene express level nlrp caspas caspas il il asc bcl measur periton cell use quantit real time pcr determin nlrp protein level measur western blot also intracellular reactiv oxygen speci ros product investig quantit compar analys show inject tachyzoit signific increas nlrp caspas caspas il il asc gene mrna express level p contrari acut infect bcl gene signific express esa group p level nlrp protein signific higher mice receiv tachyzoit esa comparison control group p find provid insid host gondii interact nlrp regul import modul immunolog respons
D014122;D014123
T204;T047
34,688,628
identif function character sirna pathway taenia crassicep silenc enolas gene silenc procedur cysticerci taeniid cestod taenia crassicep describ first time techniqu report speci wide use anim model human cysticercosi genom databas search perform order find relev gene involv gene silenc non code rna process argonaut dicer ago dcr present crassicep found three ago two dcr orthologu design tcago tc tc well tcdcr tcdcr order elucid evolutionari relationship crassicep tcago tcdcr gene separ phylogenet analys carri includ ago dcr orthologu platyhelminth find show close phylogenet relationship tcago tcdcr previous describ echinococcus spp rt pcr studi demonstr express tcago tcdcr orthologu result show gene silenc machineri crassicep function activ induc silenc tcenoa result clear show gene silenc use sirna use molecular methodolog studi gene function taeniid cestod
D003551;D013621
T204;T047
34,688,624
decreas endostatin dbdb retina associ optic disc intravitr vascular endostatin natur cleav fragment type xviii collagen antiangiogen activ involv regul neovascular diabet retinopathi intracellular distribut endostatin healthi mous human neuroretina analyz addit studi effect experiment hyperglycemia retin endostatin dbdb mous model use endostatin protein express mous human retina studi immunofluoresc western blot compar dbdb mice eye fundus angiographi histolog immunofluoresc use visual mous retin intravitr vessel first time result reveal presenc endostatin neuron mous human retina endostatin main express bipolar cell photoreceptor contrast optic disc endostatin express undetect diabet mice show reduct endostatin retina associ appear intravitr vessel optic disc dbdb mice intravitr vessel show gfap posit neuroglia sheath basement membran thicken collagen iv deposit presenc mmp mmp vascular wall togeth result point decreas retin endostatin experiment diabet associ optic disc intravitr vascular base phenotyp intravitr vessel could neovessel howev rule possibl may also repres persist hyaloid vessel
D003921
T050
34,688,623
radiotherapi induc alter vitreous humor new potenti critic structur vitreous humor vh consid critic structur radiotherapi plan process present studi experiment anim model perform examin effect radiotherapi vh right eye twelv new zealand rabbit irradi gy fraction accord scheme use treatment uveal melanoma clinic contralater left eye consid control week ophthalmolog examin perform irradi three month end third month enucl vitreous collect conduct vitreous sampl subject metabolom analys elisa analys viscos measur electron microscop examin control experiment vitreous sampl differ metabolit identifi found differ signific group multivari analyz clear distinct observ control irradi vitreous sampl pathway analysi reveal nine pathway affect pathway main relat amino acid metabol signific decreas observ express type ii v xi collagen protein level elisa non signific decreas type ix collagen viscos electron microscop examin reveal disrupt collagen fibrillar ultra structur dispers collagen fragment experiment vitreous intact vitreous essenti healthi eye studi observ radiat caus chang vitreous may long term consequ
D009374
T191;T050
34,688,621
incid predictor chronic thromboembol pulmonari hypertens follow acut pulmonari embol echocardiographi guid approach signific variabl worldwid epidemiolog chronic thromboembol pulmonari hypertens cteph therebi aim determin incid predictor cteph follow episod acut pulmonari embol pe use non invas modal patient acut pe prospect follow receiv least month effect anticoagul persist symptomat patient echocardiograph evid persist pulmonari hypertens investig cteph incid cteph delay present higher pulmonari arteri pressur present discharg greater thrombot burden signific predictor develop cteph follow acut pe
D006976;D011655
T047;T046
34,688,620
conduct abnorm post alcohol septal ablat hypertroph cardiomyopathi singl center experi conduct abnorm common note alcohol septal ablat asa retrospect observ studi studi incid new onset conduct abnorm post asa patient underw asa period year includ studi baselin conduct abnorm note patient n transient complet heart block chb note n wherea new onset right bundl branch block rbbb seen n left bundl branch block uncommon n perman pacemak implant done n chb conduct anomali frequent asa rbbb common
D002312;D006346
T023;T047
34,688,619
long term outcom bare metal stent implant long term outcom data bms implant avail indian subcontin prospect observ studi aim studi long term outcom bms implant tertiari care centr consecut patient underw bms implant follow year lad common vessel involv differ type bms implant caus mortal note n wherea cardiac mortal seen n cumul revascularis free surviv year studi show long term outcom bms implant fare accept
D054855
T074
34,688,616
surgic ventricular reconstruct elig late assist devic implant patient ischem cardiomyopathi left ventricular aneurysm format symptomat despit optim medic therapi challeng determin whether surgic ventricular reconstruct heart transplant left ventricular assist devic lvad implant treatment choic report describ concept surgic ventricular reconstruct special prepar lvad fixat ring facilit subsequ lvad implant requir patient report case endoventricular circular lvad ring plasti suffici reduc ventricular volum normal left ventricular geometri subsequ led improv left ventricular eject fraction
D006333;D006353
T074;T047;T046
34,688,615
puls electr field induc extracellular matrix remodel matrix metalloproteinas activ decreas collagen product impair extracellular matrix remodel observ tumor microenviron fibrosi result excess collagen product andor decreas degrad matrix metalloproteinas mmps thank local applic transient effect physic stimuli appear attract tool remodel extracellular matrix assess potenti puls electr field technolog classic appli drug deliveri induc collagen remodel tissu scale sophist vitro tissu engin human dermal substitut use show microsecond millisecond puls electr field induc rapid modul hour electrostimul mrna gene compos matrisom particular downregul procollagen extracellular matrix matur enzym transglutaminas lysyl oxidas like ii transient decreas procollagen product hydroxyprolin tissu content within week electrostimul iii long last ros depend overactiv matrix metalloproteinas least hour iv downregul tgf observ underpin puls electr field technolog alreadi approv clinic use combin anticanc agent particular promis provid local effect treatment abnorm extracellular matrix
D005109;D020782
T116;T024;T126
34,688,614
state resid microbi strain divers skin human skin host divers microbiota advanc sequenc analyt method increas illumin import finest resolut understand genet divers skin microbiota highlight strain level differ function implic genet divers exist within individu strong individu specif underscor difficulti elucid function integr investig microbi strain divers sequenc cultur base approach host immunolog physiolog critic expand understand role skin microbiom
D007396;D064307
T065;T097;T001;T032;T028
34,688,613
evolut male nuptial gift femal remat quantit genet model speci separ sex male present nuptial gift contain nutrit mate produc larg nuptial gift consider cost male may improv sire success femal reduc likelihood accept anoth male receiv larg gift femal may receiv direct benefit accept anoth male provid addit nuptial gift addit femal may receiv indirect fit benefit via lay offspr sire male abl produc larg nuptial gift formal multivari quantit genet model describ coevolut size nuptial gift produc male x femal propens engag remat analyz model focus two case remat femal receiv indirect fit benefit enjoy direct benefit nutrit remat femal receiv direct benefit enjoy indirect fit benefit due posit genet correl x possibl random mutat tend make male produc small nuptial gift case stabl evolutionari equilibrium neither nuptial gift remat x alway exist anoth stabl equilibrium may exist male produc nuptial gift x femal engag multipl mate discuss implic sexual conflict
D008957;D012726
T170;T054
34,688,611
evalu heparin syring measur newborn metabolit neonat central arteri line newborn metabol screen emerg novel method predict neonat morbid mortal neonat born preterm week gestat purpos studi determin blood collect electrolyt balanc dri lithium heparin syring routin blood gas measur affect target metabolit biomark level two blood sampl one collect heparin syring non heparin syring obtain time infant central arteri line test metabolit biomark use standard procedur newborn screen overal median metabolit level signific differ syring type howev wide variabl particular amino acid immunoreact trypsinogen individu pair sampl therefor consider given sampl collect use metabolit predict model neonat morbid mortal
D001800;D062905;D015997;D013594
T061;T074;T060
34,688,608
use telemedicin team improv guidelin base antibiot prescrib assess impact virtual antibiot team vat appropri antibiot prescrib behavior older care physician regard urinari tract uti respiratori tract rti skin soft tissu infect ssti resid long term care facil ltcf
D000073602;D018461;D017216;D014552
T058;T047
34,688,607
mechanist gene network infer singl cell data outlier insensit method advanc singl cell techniqu measur gene dynam cellular resolut becom practic contrast increas complex data made challeng comput unravel under biolog mechan thus critic develop novel comput method capabl deal complex provid predict deduct data mani method develop address challeng advantag limit present iter regress algorithm infer mechanist gene network singl cell data especi suit overcom problem pose measur outlier use regress infer development model gene dynam drosophila melanogast blastoderm embryo result show predict power infer model higher model infer least squar ridg regress baselin well mechanist model expect perform find model predict gene dynam accur predict made neural network vari architectur complex hold true even limit small sampl size compar predict various gene knockout publish experiment result find substanti qualit agreement also make predict gene dynam various gene network perturb imposs non mechanist model
D004331;D053263
T044;T204
34,688,605
clinic efficaci botulinum toxin treatment plantar fasciiti systemat review meta analysi random control trial evalu efficaci botulinum toxin btx treatment plantar fasciiti meta analysi random control trial rcts focus pain function outcom sinc current literatur support potenti benefit btx
D019274;D036981
T116;T047;T121;T109;T129;T131
34,688,603
liquid chromatographi tandem mass spectrometri method semiquantit screen cellular acyl coa studi describ lc esi msms method cover analysi various cellular acyl coa singl inject method base quick extract step elimin llesp clean method perform characterist determin spike acyl coa standard differ concentr surrog matrix extens matrix effect acyl coa except palmitoyl coa compens use isotop label intern standard matrix match calibr result high matrix effect accuraci palmitoyl coa low concentr deviat target rang develop method appli identifi twenti one cellular acyl coa sk hep cell screen alter acyl coa level post mito q antioxid intervent
D000214
T114;T123
34,688,602
deep learn base synthesi post contrast weight mri tumour respons assess neuro oncolog multicentr retrospect cohort studi gadolinium base contrast agent gbcas wide use enhanc tissu contrast mri scan play crucial role manag patient cancer howev studi shown gadolinium deposit brain repeat gbca administr yet unknown clinic signific aim assess feasibl diagnost valu synthet post contrast weight mri generat pre contrast mri sequenc deep convolut neural network dcnn tumour respons assess neuro oncolog
D000077321;D016571
T170;T066
34,688,599
high flow priapism pediatr popul case seri review literatur priapism prolong erect last longer four hour rare patholog pediatr popul estim per children per year diagnost sequenc includ clinic histori physic examin penil doppler ultrasound pdus punctur corpora cavernosa alway necessari establish differenti diagnosi high flow low flow priapism treatment choic pediatr age well defin
D011317
T047
34,688,596
cohort studi factor impair semen qualiti transgend women transgend women peopl assign male gender birth femal gender ident choos cryopreserv semen medic transit retain possibl parent genet relat offspr later life previous retrospect studi show semen qualiti transgend women decreas compar general popul etiolog impair semen qualiti remain larg unknown howev impair semen qualiti might relat habitu behavior typic observ transgend women exampl desir hide testicl genit dysphoria therefor decid conduct consecut studi prospect obtain data behavior lifestyl transgend women
D063106;D014189
T032;T098
34,688,595
pelvic organ prolaps follow hysterectomi benign indic nationwid nullipar cohort studi hysterectomi common perform may increas risk pelvic organ prolaps previous studi parous women shown increas risk pelvic organ prolaps surgeri hysterectomi pariti strong risk factor pelvic organ prolaps may confus true relat hysterectomi pelvic organ prolaps
D056887
T047;T020
34,688,594
surviv outcom resuscit process measur matern hospit cardiac arrest matern hospit cardiac arrest rare event potenti resuscit treatment delay difficulti access hospit obstetr unit limit simul train resuscit experi obstetr staff howev unclear whether surviv rate process care differ women matern hospit cardiac arrest nonmatern hospit cardiac arrest
D016887;D006323
T047;T061;T046
34,688,593
structur function insight gsu uniqu multihem cytochrom g sulfurreducen geobact sulfurreducen possess cytochrom assur effect electron transfer cell exterior abund group cytochrom microorgan ppca famili compos five periplasm trihem cytochrom high structur homolog ident heme coordin gsu periplasm trihem cytochrom synthet g sulfurreducen fe iii reduc condit present cultur grown fumar cytochrom low sequenc ident ppca famili cytochrom differ heme coordin base analysi amino acid sequenc work amino acid sequenc analysi site direct mutagenesi complementari biophys techniqu includ ultraviolet visibl circular dichroism electron paramagnet reson nuclear magnet reson spectroscopi use character gsu cytochrom low percentag secondari structur element featur helic sheet nuclear magnet reson show protein contain three low spin heme fe ii reduc state electron paramagnet reson show oxid state one heme becom high spin fe iii wherea two other remain low spin fe iii data obtain also indic heme group distinct axial coordin appar midpoint reduct potenti gsu mv ph independ physiolog rang howev ph modul reduct potenti heme undergo low high spin interconvers reduct potenti valu cytochrom gsu distinct compar ppca famili member provid protein larger function work redox potenti rang overal result obtain togeth amino acid sequenc analysi differ multihem cytochrom famili indic gsu member new group trihem cytochrom
D001426;D003580;D005290
T116;T104;T123
34,688,591
mri characterist intralabyrinthin schwannoma post contrast h delay flair imag purpos studi describ mri characterist intralabyrinthin schwannoma il post contrast three dimension fluid attenu invers recoveri flair imag obtain four hour intraven administr gadolinium base contrast agent h flair
D018159;D009442
T191;T047
34,688,590
effect covid train mental health oral medicin resid north america object studi assess resid faculti percept effect coronavirus diseas pandem train experi educ psycholog well oral medicin om resid
D000086382;D007396
T097;T065;T047;T067
34,688,589
evid base urolog subgroup analysi random control trial random control trial investig often explor possibl treatment effect differ subgroup eg women vs men old vs young versus less sever diseas investig often inappropri claim subgroup effect also call effect modif interact likelihood true effect modif low criteria assess credibl subgroup analys nice summar formal instrument assess credibl effect modif analys iceman includ investig postul priori hypothes specifi direct support prior evid low likelihood chanc explain appar subgroup effect test small number subgroup hypothes patient summari random clinic trial often use subgroup analys explor whether treatment less effect particular patient subgroup eg women vs men old vs young mini review explor common pitfal subgroup analys
D014572
T091
34,688,587
evid base urolog studi meta analysi big enough design clinic studi draw conclus studi effect treatment requir justif sampl size via judici choic endpoint power priori power calcul limit chanc mistaken claim lack clinic signific statist signific differ two treatment detect calcul sampl size new trial furthermor requir assess exist evid determin result contribut updat meta analysi rate power meta analysi determin optim inform size suggest follow principl calcul power singl trial even though sampl size consider might seem like addit hurdl necessari conduct clinic studi meta analysi provid optim benefit clinician patient patient summari conduct clinic trial research determin mani patient need includ detect differ treatment even though studi might find statist differ treatment necessarili mean differ relev clinic use analys start studi import produc worthwhil usabl evid clinician patient
D018401;D014572
T091;T081
34,688,586
parent view care babi robin sequenc robin sequenc parent present view robin sequenc healthcar provid engag practic may outdat excess invas unnecessarili detriment qualiti life propos possibl area research improv patient outcom
D010855
T019
34,688,584
femal genit self imag modif increas genit cosment surgeri past decad common procedur labiaplasti trend mani origin signific motiv genit self imag shown cultur influenc furthermor genit self modif way groom also felt play role desir surgic alter one genit appear given cultur aspect practic sexual health proivder awar role self imag self modif drive toward persu surgic chang genit schmidt cn rowen ts femal genit self imag modif j sex med
D001828;D012649
T080;T041
34,688,582
midwiv provid woman centr care covid pandem australia nation qualit studi covid pandem caus isol fear impact matern healthcar provis
D000086382;D008880
T097;T091;T047;T067
34,688,581
person protect equip train non healthcar worker covid pandem effect evid base skill train framework larg scale quarantin facil staf non healthcar worker nhcw instrument prevent communiti spread covid coronavirus diseas object studi determin effect newli develop procedur skill train framework ensur person protect equip ppe complianc ppe nave nhcws
D000086382;D000067393
T047;T073;T067
34,688,580
clinic outcom healthcar resourc util relat cost coher model applic heart failur patient composit endpoint wide use sever limit clinic outcom healthcar resourc util relat cost coher model new approach visual display compar composit endpoint includ compon incid time durat relat cost aim assess valid coher model patient cohort
D006333;D006760
T058;T047;T046
34,688,579
highlight th annual scientif meet societi cardiovascular comput tomographi th societi cardiovascular comput tomographi scct annual scientif meet welcom digit attende countri program includ session across three simultan stream channel exhibitor poster present hour demand video main theme meet includ coronari arteri diseas valvular heart diseas structur heart diseas advanc analyt includ machin learn articl summari main theme meet key present shape futur cardiovascular comput tomographi clinic practic
D014057
T060
34,688,577
level align time periodont status patient sever upper crowd treat corticotomi assist self ligat bracket comparison convent self ligat bracket arm random control clinic trial lengthi period time requir one main reason patient refus orthodont treatment addit treatment may negat effect periodont tissu
D008310;D016910
T190;T033;T074;T078
34,688,576
epidemiolog clinic characterist macrolid suscept mycoplasma pneumonia pneumonia children southern taiwan sinc global use pneumococc conjug vaccin mycoplasma pneumonia mp becom common bacteri caus lower respiratori tract infect among children monitor chang epidemiolog antimicrobi resist rate organ import mp clinic manag
D017714;D011019;D012141
T047
34,688,575
isol bioactiv compound lichen parmelia sulcata evalu antimicrobi properti lichen use ailment tradit medicin treat various disord centuri sinc less evid literatur medicin properti parmelia sulcata p sulcata made pioneer attempt explor antioxid antimicrobi properti lichen
D000890;D008011
T121;T002
34,688,573
diagnost approach neonat infantil cholestasi posit paper sigenp liver diseas work group neonat infantil cholestasi nic repres onset surgic correct diseas genet metabol disord worthi medic treatment time recognit nic identif under etiolog paramount improv outcom upon invit italian nation institut health iss expert work group form formul evid base posit current knowledg diagnosi nic systemat literatur search conduct collect evid epidemiolog etiolog clinic aspect accuraci avail diagnost test nic evid score use grade system recommend approv panel expert upon agreement least member final document approv panel compon posit document summar collect statement defin best evid diagnost approach cholestasi first year life
D002779;D019317;D007232;D017410
T091;T047;T170;T078
34,688,570
racial dispar bariatr periop outcom among elder bariatr surgeri outcom elder patient shown safe higher rate advers outcom compar noneld patient impact race bariatr surgeri outcom continu explor recent studi show higher rate advers outcom black patient periop outcom racial cohort elder bariatr patient larg unexplor
D050110;D015390;D009767
T047;T061
34,688,569
vitro comparison tensil strength elastomer ligatur expos povidon iodin chlorhexidin hydrogen peroxid orthodont patient use chemic substanc oral environ could chang elastomer properti applianc sinc begin sar cov pandem effort devot explor method prevent includ use antivir mouthwash studi aim investig effect povidon iodin pvp two disinfect solut mechan properti orthodont elastomer ligatur
D009967
T074
34,688,568
evalu corticis base acceler lower anterior teeth align term root resorpt dehisc format use cone beam comput tomographi young adult patient random control trial random control trial rct compar flapless corticis convent treatment non extract treatment crowd lower anterior teeth lat term extern apic root resorpt earr dehisc format df aim rct investig two complic level align lat use cone beam comput tomographi cbct imag
D008310;D012391;D014091
T190;T033;T047;T078
34,688,567
burnout resili among pharmaci technician singapor studi burnout describ emot exhaust ee deperson dp low person achiev caus work known bring negat consequ practition patient health system various organiz person factor organiz strategi resili associ phenomenon howev pauciti data describ preval burnout among pharmaci staff within singapor asia especi pharmaci technician pt popul
D002055;D010596
T097;T048
34,688,566
explor covid vaccin hesit rural histor black colleg univers minor disproportion affect coronavirus diseas covid yet lowest covid vaccin rate vaccin hesit report higher rate african american aa young adult studi aim assess covid vaccin hesit determin rational receiv declin covid vaccin propos strategi address confid faculti staff student rural histor black colleg univers hbcu
D000086382;D000086663
T047;T200;T067
34,688,565
trust influenc communiti pharmacist pharmaci central address vaccin hesit world health organ list vaccin hesit defin reluct refus vaccin prevent infecti diseas one top ten threat global health address hesit must focus attent build vaccin confid trust vaccin provid administ vaccin process lead vaccin licensur recommend vaccin schedul build vaccin confid particular communiti higher level distrust vaccin low vaccin coverag rate critic public health prioriti particular current climat unit state global public health communiti grappl coronavirus diseas pandem commentari focus central role pharmacist play promot health well local communiti embed one trust sourc communiti come health inform care uniqu posit make profound contribut build vaccin confid propos arm health profession tool aspir framework serv seri action step facilit convers communiti framework intend assist pharmacist communic communiti member may concern vaccin share trustworthi health inform vaccin increas vaccin adopt conclud insuffici mere relay accur health inform vaccin public expect dramat increas vaccin rate accur health inform need convey trust sourc open engag dialogu layer top fundament fact messag central build confid pharmacist provid use tool aspir guid convers communiti member increas vaccin adopt
D000086382;D010594;D014612
T116;T047;T121;T073;T129;T093;T067;T058
34,688,564
system approach plant breed illustr tree linkag new creativ way exist plant breed method respons differ global trend valu provid system approach address broad set global product challeng effect illustr approach applic tree chosen extens divers featur use user product context domest pathway coin result strategi tree divers breed consid refer trend valu relat particip environ biotechnolog market exampl featur approach tree applic plant breed wide seek address complex problem strateg biodivers use
D000069600;D014197
T040;T002
34,688,562
quantit review farm feed practic enhanc qualiti grassland base rumin dairi meat product last decad larg bodi evid highlight major role feed manag practic improv specif nutrit technolog sensori qualiti trait rumin product howev result most obtain control condit rare valid farm therefor quantit review conduct quantifi effect farm feed manag practic carotenoid fat solubl vitamin colour fatti acid fas terpen sensori properti main anim product categori pcs dairi product cattl dc sheep ds goat dg meat cattl mc sheep ms four feed scenario select accord consist farm studi literatur feed fresh herbag instead conserv forag b ban form silag silag free c ban maiz silag maiz silag free feed forag perman grassland rich speci plant secondari metabolit psms psm rich perman grassland feed fresh herbag increas concentr carotenoid fat solubl vitamin n fa rumen acid branch chain fa bcfa reduc concentr satur fa pc overal stronger effect dairi product meat textur meat dairi product margin affect wherea feed fresh herbag decreas lactic increas veget note dc silag free feed scenario result increas vaccen acid rumen acid bcfa cn dc maiz silag free feed scenario lower n fa wherea increas n rumen acid bcfa concentr dc feed rumin forag psm rich perman grassland increas monounsatur fa n fa rumen acid decreas n fa dairi product margin affect meat fa composit dc psm rich perman grassland show higher intens spici anim note overal differ feed manag practic observ farm smaller observ control trial sever confound factor control oper farm condit could origin diverg ie mix diet forag characterist anim relat factor review confirm farm practic may differ affect sever qualiti trait rumin product also highlight uneven knowledg effect feed manag depend pc larger milk meat decreas move cattl sheep sheep goat
D007774;D008461
T042;T168
34,688,561
improv cancer treatment via dynam biophys model despit signific advanc oncolog research cancer nowaday remain one main caus mortal morbid worldwid new treatment techniqu rule limit efficaci target narrow rang oncolog diseas limit avail general public due high cost import goal oncolog thus modif type antitumor therapi combin alreadi introduc clinic practic goal increas overal treatment efficaci one option achiev goal optim schedul drug administr perform medic action sever factor complic task advers effect treatment healthi cell popul must kept toler emerg drug resist due intrins plastic heterogen cancer cell popul interplay differ type therapi administ simultan mathemat model tumor microenviron consid singl complex system address complex indic potenti effect protocol would requir experiment verif review consid classic method current trend futur prospect field mathemat model tumor growth treatment particular method treatment optim discuss sever exampl specif problem relat differ type treatment
D009369
T191
34,688,558
effect inorgan carbon limit nitrogen remov perform singl stage reactor contain anammox nitrit gel carrier herein effect inorgan carbon ic limit nitrogen remov perform singl stage reactor contain nitrit anammox gel carrier investig result continu feed test effluent ammonium concentr increas ic concentr decreas indic deterior nitrit activ anammox furthermor sensit ic anammox nitrit activ investig anammox nitrit reactor respect consequ relationship effluent ic concentr nitrit rate well describ use micha menten equat appar k valu nitrit calcul mg c l anammox reactor calcul mg c l result reveal affin nitrit gel carrier ic lower anammox support nitrit activ easili deactiv decreas ic concentr rather anammox microbi communiti analysi reveal nitrosomona europaea candidatus jettenia asiatica domin speci ammonium oxid anammox bacteria
D064751;D009584
T196;T104;T197;T123
34,688,555
ag singl nucleotid polymorph oprm risk factor asthma sever although popul studi implic emot burden asthma sever under genet risk factor complet understood aim evalu genet influenc function singl nucleotid polymorph snp stress relat opioid receptor gene oprm ag snp rs asthma sever
D012720
T080;T081
34,688,553
parent adolesc convers covid influenc adolesc empath concern adher health protect behavior longitudin investig assess frequenc parent adolesc convers covid moder adolesc stress influenc adolesc empath concern adher health protect behavior hpbs throughout first year covid pandem
D000294;D000086382
T047;T067;T055
34,688,552
pilot studi music wait room outpati pain clinic studi explor live record music listen outpati pain clinic evid demonstr effect live record music hospit set comparison studi kind yet conduct
D009146;D009147
T170;T061
34,688,551
muggl guid deep learn wizardri grow interest applic artifici intellig ai particular deep learn dl nuclear medicin radiolog partit profession communiti one end spectrum expert dl wizard develop potion like code wave dl capabl like wand across profess opposit side spectrum muggl colleagu lack wizardri dl may larg oblivi entir magic realm
D000077321;D009683
T091;T066
34,688,550
studi investig undergradu diagnost radiograph prefer expect clinic role develop quantit find whilst unit kingdom uk student ambit role develop survey previous literatur explor specialis prefer studi aim explor ambit prefer final year diagnost radiographi undergradu higher educ institut hei north west england
D000488;D009042
T097;T080;T041;T078
34,688,549
role proton therapi esophag cancer physic properti proton beam radiat therapi pt allow energi deposit specif depth rapid energi fall beyond depth pt sever theoret advantag photon radiat therapi esophag cancer ec proton potenti reduc dose healthi tissu safe allow treatment tumor near critic organ dose escal trimod treatment irradi recent year larger multicent retrospect studi publish show excel surviv rate lower expect toxic even better outcom pt photon radiotherapi even use imrt vmat techniqu although pt associ reduc toxic postop complic hospit stay compar photon radiat therapi studi inher bias relat patient select pt observ recent confirm random phase ii studi local advanc ec show signific reduc toxic proton compar imrt current two random phase iii trial nrg gi us protect europ conduct confirm whether proton could becom standard care local advanc resect esophag cancer
D004938;D061766;D050397;D000069475
T191;T061
34,688,548
adapt radiat therapi benefit literatur provid identifi current literatur right time replan assign threshold optimum process replan nowaday adapt radiotherapi art head neck cancer play except role consist evalu procedur promin anatom dosimetr variat perform complex radiotherapi method credibl therapeut result crucial imag guid radiotherapi igrt develop ensur locoregion control thus chang might occur radiotherapi dealt
D006258;D061089;D050397
T191;T061
34,688,547
relationship ventricular assist devic support durat pediatr heart transplant outcom wide variabl time heart transplant htx pediatr vad implant center wait month list htx other accept donor heart offer within day vad surgeri sought determin htx within day versus vad impact post htx outcom
D016027;D006353
T074;T061
34,688,546
molecular characteris carbapenem tigecyclin resist klebsiella pneumonia strain isol blood bile sampl number carbapenem resist klebsiella pneumonia crkp strain increas rais healthcar concern worldwid studi isol three crkp strain bile blood sampl elder patient acut cholang characteris featur antimicrobi resist mechan crkp isol
D007710;D007711
T007;T047
34,688,544
activ system treatment cabozantinib failur advanc metastat renal cell carcinoma cabozantinib potent multityrosin kinas inhibitor tki demonstr overal surviv os benefit everolimus patient previous treat vegfr tki metastat renal cell carcinoma mrcc efficaci system treatment cabozantinib failur investig
D000970;D002292;D007680
T191;T121;T109
34,688,543
post acut covid syndrom anesthesiologist narrat review pragmat approach clinic care post acut coronavirus diseas covid syndrom novel poor understood clinic entiti life impact ramif patient syndrom also known covid long hauler often present nonspecif ailment involv one bodi system common complaint includ dyspnea fatigu brain fog chest pain current singl agre upon definit post acut covid syndrom agre criterion syndrom persist mental physic health consequ initi infect given million acut infect unit state cours pandem periop provid encount patient clinic practic grow number symptom covid long hauler minim patient higher risk postop respiratori complic periop mortal seven week initi ill instead cautious multidisciplinari preoper evalu perform periop care view prism best practic alreadi use avoid benzodiazepin patient cognit impair use lung protect ventil recommend especi relev covid long hauler includ assess critic care myopathi neuropathi determin suitabl neuromuscular block agent revers preoper workup insidi cardiac pulmonari patholog previous healthi patient thorough medic review particular anticoagul regimen chronic steroid use articl author defin syndrom synthes avail scientif evid make pragmat suggest regard periop clinic care covid long hauler
D000086382
T047;T067
34,688,541
improv support care home parent need prefer care children medic complex sought character current support use parent care children medic complex cmc home parent prefer addit support meet identifi gap
D006699;D010290
T058;T102;T099
34,688,540
phosphat overload stimul inflammatori reaction via pit induc vascular calcif uremia vascular calcif vc import risk factor cardiovascular diseas mainten hemodialysi mhd patient hyperphosphatemia microinflamm statement known major contributor develop vc howev mechan unknown aim studi explor risk factor vc mhd patient explor whether high phosphat could increas secret inflammatori cytokin via pit monocyt
D054559;D014511;D061205
T047
34,688,538
optim pediatr induct experi use human center design anesthesia inhal induct fall asleep surgeri use medic mask often stress children children becom anxious induct may resist wear anesthesia mask high anxieti induct associ poorer outcom surgeri increas emerg delirium increas pain negat behavior chang discharg purpos project design optim anesthesia induct experi children focus decreas patient anxieti inhal induct
D000071257
T048
34,688,537
fast track patient academ hospit increas effici decreas discharg delay process improv plan purpos qualiti improv project determin implement phase ii postanesthesia care unit pacu ii fast track patient follow surgeri academ hospit would decreas hold time increas patient flow effici
D010351;D011997
T058;T093;T073
34,688,536
koyanagi urethroplasti proxim hypospadia stage procedur report experi technic refin koyanagi urethroplasti proxim hypospadia
D005402;D007021;D014525
T190;T047;T019
34,688,535
advanc glycat end product via skin autofluoresc potenti marker carotid atherosclerosi patient type diabet advanc glycat end product age report correl diabet vascular complic studi aim investig associ age carotid atherosclerosi cas surrog marker cardiovascular diseas cvd
D002340;D017127;D012879
T047;T109;T123;T042;T070
34,688,534
optim follow patient suspici multiparametr mri subsequ negat target prostat biopsi result larg singl institut seri aim optim follow patient posit multiparametr magnet reson prostat mpmri subsequ negat target biopsi tbx plus systemat biopsi sbx
D000081364;D011471
T191;T060
34,688,533
assess diagnost perform systemat freehand precisionpoint transperin prostat biopsi comparison observ outcom pbcg nomogram predict assess diagnost perform freehand systemat transperin biopsi ftpb use prostat biopsi collabor group pbcg nomogram contemporari updat pcpt nomogram
D049451
T170;T081
34,688,532
prognost superior global longitudin strain beyond four tier ventricular hypertrophi asymptomat individu studi aim explor clinic correl myocardi deform use speckl track algorithm determin prognost util measur asymptomat ethnic chines popul
D006333;D017379
T047;T046
34,688,531
longitudin assess health util score symptom toxic patient small cell lung cancer use real world data recent advanc small cell lung cancer sclc treatment necessit better understand real world health util score hus patient treat current standard facilit robust pharmaco econom assess
D006304;D011788;D012720
T080;T081;T078
34,688,530
assess promot respons interact parent children qualit studi experi child health care nurs sweden one main task child health care nurs assess promot respons interact secur connect children parent futur studi aim develop understand swedish child health care nurs experi assess promot respons interact parent children
D000067576;D010290
T058;T102;T099;T078
34,688,529
determin factor low birth weight indonesia find indonesian demograph health survey low birth weight lbw still signific problem indonesia affect growth develop infant also one factor increas risk develop chronic diseas later life
D007230
T033;T101
34,688,528
hand hygien mask wear behavior relat factor covid pandem cross section studi secondari school student turkey research conduct determin hand hygien mask wear behavior relat factor secondari school student covid pandem process
D000086382;D063373
T055;T047;T067
34,688,527
debrid realli best periprosthet joint infect follow total ankl replac systemat review meta analysi ankl periprosthet joint infect rise number evid base gold standard treatment defin yet
D001170;D058737;D016459
T047;T061;T046
34,688,524
liver transplant budd chiari syndrom challeng handabl procedur establish venous outflow liver transplant patient budd chiari syndrom crucial requir various surgic techniqu outcom patient exibit distinct problem includ vasculari thrombosi biliari complic
D006502;D016031;D013927
T047;T061;T046
34,688,523
prescrib pediatr hospit set lost translat determin parent understand direct common pediatr prescript pharmaci label identifi enabl barrier affect interpret label
D008508;D055553
T033;T080;T121
34,688,522
systemat search review discrimin health care measur adapt discrimin occur health care set contribut health inequ yet guidanc best measur discrimin health care still limit
D003695;D063505
T058;T093;T054
34,688,521
storybook healthi beverag consumpt effect onlin random experi parent parent spend substanti time read children make storybook promis understudi avenu motiv parent serv children healthier beverag studi examin parent reaction messag promot healthi beverag consumpt embed children storybook
D001628;D010290
T102;T168;T099
34,688,520
efficaci cost nanocrystallin silver dress versus silver sulfadiazin dress treat burn adult outpati set random clinic trial nanocrystallin silver dress reduc number chang facilit burn wound manag howev evid regard efficaci cost consequ compar well establish treatment silver sulfadiazin still scarc
D000891;D002056
T121;T037
34,688,519
bacteri composit subgingiv plaqu crowd noncrowd teeth patient dental crowd even good oral hygien may show increas bacteri presenc crowd area studi aim determin microbi composit subgingiv plaqu crowd noncrowd dental region
D003773;D008310
T190;T033;T047;T078
34,688,518
impact covid pandem us orthodont practic studi aim investig immedi impact long term implic sever acut respiratori syndrom coronavirus orthodont practic unit state
D000086382;D058873
T047;T067
34,688,517
superimposit serial dimension facial photograph assess chang time systemat review superimposit dimension photograph enabl thorough risk free assess facial chang time howev avail method evid support assess systemat paper summar assess current evid superimposit method serial dimension facial photograph avail literatur
D005145
T029
34,688,516
esthet impact maxillari midlin diastema mandibular crowd children mix dentit studi aim investig esthet impact mandibular crowd maxillari midlin diastema children mix dentit
D003970;D008310
T190;T033;T078
34,688,515
mir p negat associ atrial fibrosi promot atrial remodel target creb atrial fibril progress atrial fibrosi vital atrial remodel atrial fibril af main object present studi explor associ mir p atrial fibrosi well result impact atrial remodel af
D001281;D064752;D035683
T123;T047;T114;T046
34,688,513
surviv outcom right versus left side colon cancer rectal cancer england propens score match popul base cohort studi aim studi evalu year overal surviv os patient oper potenti curabl right versus left side colon cancer rectal cancer england
D003110;D012004
T191
34,688,512
diagnosi strategi adipocyt soft tissu tumor adult consensus european expert fat contain tumor common found daili practic benign lipoma account major superfici tumor overlap imag find benign intermedi malign fat contain tumor common guidelin recommend core needl biopsi cnb deep tumor superfici tumor cm howev specif strategi diagnosi referr sarcoma center appli adipocyt tumor aim consensus statement provid specif algorithm adipocyt tumor discrimin patient requir cnb preoper diagnosi simpli undergo activ surveil simpl excis
D008067;D008080;D012509;D012983
T191
34,688,509
sleep qualiti children adolesc attent deficit hyperact disord sleep disturb associ increas risk attent deficit hyperact disord adhd also lead sleep problem studi aim determin variabl affect relationship adhd sleep qualiti moreov aim compar variabl children adolesc adhd healthi control cross section studi conduct use random sampl adhd patient healthi children turkey self administ questionnair distribut assess sleep qualiti use pittsburgh sleep qualiti index psqi risk impair sleep qualiti associ presenc adhd ci presenc somat diseas ci famili histori psychiatr disord ci psqi total score higher children parent separ compar without parent separ p econom level particip decreas psqi total score increas signific p determin combin type adhd associ impair sleep qualiti subtyp p p respect find show children adhd signific sleep problem healthi control sociodemograph variabl famili characterist affect sleep qualiti healthi children children adhd
D000089943
T033
34,688,508
stage versus concurr nativ nephrectomi renal transplant patient autosom domin polycyst kidney diseas systemat review patient autosom domin polycyst kidney diseas adpkd frequent undergo nativ nephrectomi transplant nephrectomi may stage procedur undertaken simultan transplant perform simultan transplant procedur prolong involv larger oper field incis also concern greater risk graft loss simultan nephrectomi transplant moreov stage surgeri may allow nephrectomi perform immunosuppress introduct via smaller incis involv minim invas approach howev stage nephrectomi may requir period dialysi otherwis necessari transplant nephrectomi simultan moreov singl procedur need impli avoid prior nephrectomi attend morbid patient chronic renal insuffici account issu studi aim compar cumul morbid two stage procedur versus singl simultan approach term morbid graft outcom
D016030;D016891
T047;T019;T061
34,688,506
translat violenc prevent program research practic saferteen implement urban emerg depart youth violenc lead caus adolesc mortal underscor need integr evid base violenc prevent program routin emerg depart ed care
D004632;D014754
T058;T048;T093;T061
34,688,505
effect cochlear implant cognit function older adult prospect longitudin year follow studi shown elimin hear loss mid life may reduc risk deterior cognit function cochlear implant ci avail therapi elimin hear loss patient suffer profound sensorineur hear loss suggest may posit effect hear level cognit older adult follow ci therefor purpos studi clarifi whether cognit function improv maintain use cochlear implant older adult patient hear impair
D019929;D003054;D003638;D034381;D006319;D013067
T047;T184;T074;T041;T061;T033
34,688,502
extern tissu expans complex extrem reconstruct skin graft flap base reconstruct convent treatment complex extrem wound howev method associ relat high complic rate involv increas level complex extern tissu expans recent emerg attract altern convent counterpart technic simpl low morbid techniqu complex wound reconstruct articl provid review intern extern tissu expans focus evolut indic recent success extern expans soft tissu coverag
D019651;D017695
T037;T061
34,688,501
treat n neck earli stage oral cancer paus assess incid metastas follow neck dissect appar lymph node negat neck oral cancer earli resect cervic metastas may well increas surviv modern imag techniqu reduc yield previous undiagnos metastat node elect neck dissect end audit consecut case conduct determin proport undiagnos nodal metastas end neck metastas case main micrometast likelihood nodal metastas appar primari tumour greater mm thick length inpati stay increas day free vascularis transfer complic includ cranial nerv damag two peri oper death ipsilater neck failur occur median follow day reduc unnecessari end resect undertaken prior procedur subsequ carri end tumour greater mm unfavour tumour characterist
D002294;D009062
T191
34,688,500
canadian parent percept covid vaccin intent vaccin children result cross section nation survey vaccin children year old import control covid pandem parent primari decis maker children aim assess parent percept intent regard covid vaccin children includ underserv popul eg newcom indigen peopl visibl minor group
D000086382;D000086663
T047;T200;T067
34,688,499
infant serotyp specif anti capsular immunoglobulin g antibodi risk invas group b streptococc diseas past studi main investig associ serotyp specif capsular igg mother risk reduct invas group b streptococcus gbs young infant effici transplacent transfer igg could affect multipl matern factor henc investig infant serum gbs anti capsular igg risk reduct invas gbs diseas may robust generaliz match case control studi infant serum serotyp specif capsular polysaccharid ia iii igg concentr analyz infant invas gbs case healthi control born women recto vagin colon homotyp serotyp use bayesian model antibodi concentr gml gml predict reduc risk invas diseas serotyp ia iii respect data contribut possibl licensur gbs polysaccharid protein conjug vaccin target pregnant women base serolog correl protect invas gbs diseas
D000907;D013290
T129;T047;T116
34,688,498
resourc alloc differ type vaccin covid tradeoff synergi efficaci reach vaccin shortag suppli chain challeng caus limit access mani resourc limit countri covid pandem one primari decis vaccin order decis maker alloc limit resourc differ type vaccin effect studi tradeoff efficaci reach two vaccin type becom avail differ time
D000086382;D014612
T116;T047;T121;T129;T067
34,688,497
bcg induc immun profil household contact leprosi patient differenti protect diseas leprosi infecti diseas caus mycobacterium lepra lead irrevers disabl along social exclus leprosi spectral diseas clinic outcom lepra infect determin host factor spectrum span anti inflammatori helper th immun concomit larg number bacteria well antibodi lepra antigen multibacillari mb leprosi paucibacillari pb leprosi characteris strong pro inflammatori th well th immun despit decad avail adequ antibiot treatment transmiss lepra unab sinc individu close frequent contact untreat leprosi patient particular risk develop diseas prophylact strategi current focus household contact newli diagnos patient shown bcg vaccin reduc risk leprosi howev bcg immunoprophylaxi contact leprosi patient also report induc pb leprosi indic bcg vaccin may tip balanc protect immun overactiv immun caus skinnerv tissu damag order identifi risk develop pb leprosi bcg vaccin amongst individu chronic expos lepra analyz innat adapt immun marker whole blood household contact newli diagnos leprosi patient bangladesh receiv bcg vaccin control individu area without known contact leprosi patient similar assess data show ad effect bcg vaccin immun marker top effect alreadi induc lepra exposur moreov identifi bcg induc marker differenti protect diseas prone immun contact
D001500;D007918
T129;T047;T121;T116
34,688,496
nt feel like number impact nurs care manag provis buprenorphin treatment primari care set promot increas access retent buprenorphin treatment opioid use disord new york citi nyc depart health mental hygien dohmh implement buprenorphin nurs care manag initi bncmi nurs care manag ncms coordin buprenorphin treatment safeti net primari care clinic explor patient experienc care receiv ncms dohmh staff conduct person depth interview patient current receiv buprenorphin treatment bncmi clinic particip patient receiv receiv buprenorphin treatment bncmi one particip safeti net primari care practic
D002047;D009293
T048;T121;T109
34,688,493
impact routin post anesthesia care unit extub pediatr surgic patient safeti oper room effici maxim oper room effici essenti hospit cost contain effect patient throughput littl data avail regard safeti efficaci extub children post anesthesia care unit pacu nurs rather sought evalu impact long stand practic pacu extub upon airway complic effici
D000758;D000086382
T047;T061;T067