PMID int64 27.8M 36.2M | Title/Abstract stringlengths 7 10.7k | MeshTerms stringlengths 7 104 | SemanticTypes stringlengths 4 84 |
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34,686,046 | accur predict mutat induc frequenc shift chlorophyl protein simpl electrostat model photosynthet pigment protein complex control local chlorophyl chl transit frequenc varieti electrostat steric forc site direct mutat modifi local spectroscop tune provid critic insight nativ photosynthet function offer tantal prospect c... | D009154;D055672 | T070;T045 |
34,686,044 | structur benzothiadiazin zwitterion phospholipid cell membran use drug deriv benzothiadiazin bicycl heterocycl benzen deriv becom widespread treatment diseas hypertens treat diuret bendroflumethiazid chlorothiazid low blood sugar treat non diuret diazoxid human immunodefici virus among other work investig interact benz... | D002784;D010743 | T121;T109;T123 |
34,685,782 | spontan calcium oscil differenti calcium imag analysi rat cochlear nucleus neural stem cell causal therapi auditori pathway inner ear diseas still yet avail clinic applic regen medicin approach discuss examin possibl therapi option neural stem cell could play role regener auditori pathway recent year neural stem progen... | D020013;D002454;D007091 | T043;T066 |
34,685,781 | pancreat cell glcnac transferas overexpress increas suscept metabol stressor femal mice nutrient sensor glcnac transferas ogt sole enzym add glcnac modif onto protein play critic role pancreat cell surviv insulin secret hypothes cell ogt overexpress would confer protect cell failur respons metabol stressor high fat die... | D013312 | T121;T039;T046;T032;T040 |
34,685,779 | ethylen induc sound stimul enhanc anthocyanin accumul grape berri skin direct upregul udp glucos flavonoid glucosyltransferas global warm result loss anthocyanin accumul berri skin sound stimul use potenti method enhanc fruit color develop sinc mani plant recogn sound vibrat extern stimulus alter physiolog status respo... | D013016;D015854 | T044;T070 |
34,685,778 | plasma biomark profil heart failur patient preserv eject fraction spironolacton treatment result aldo dhf trial pathophysiolog heart failur preserv eject fraction hfpef poor understood therapeut strategi lack studi aim identifi plasma protein pathophysiolog relev hfpef respect spironolacton induc effect assess biomark ... | D013318 | T033;T034;T201 |
34,685,777 | relationship plasma proteom chang inflammatori marker bariatr surgeri sever obes diseas associ multipl advers effect health metabol bariatr surgeri mbs signific effect multipl bodi system shown improv inflammatori marker previous short term follow studi evalu associ chang inflammatori marker crp il tnf circul protein m... | D050110 | T061 |
34,685,776 | metagenom profil fecal deriv bacteri membran vesicl crohn diseas patient past mani studi suggest crucial role dysbiosi gut microbiota etiolog crohn diseas cd howev despit import player host bacteria interact role bacteri membran vesicl mv larg overlook pathogenesi cd studi address composit bacteri mv composit fecal sam... | D056186 | T091 |
34,685,774 | neuron radial glial cell communic via bmpid signal key long term mainten regen capac adult zebrafish telencephalon central nervous system adult zebrafish display extraordinari neurogen regen capac zebrafish adult brain regen capac reli neural stem cell nscs care manag nsc pool howev mechan control nsc pool mainten yet ... | D002450 | T043 |
34,685,766 | respiratori syncyti virus matrix protein chromatin associ key transcript inhibit infect cell morbid mortal caus global preval human respiratori pathogen respiratori syncyti virus rsv approach world wide influenza previous demonstr rsv matrix protein shuttl signal depend fashion host cell nucleus cytoplasm traffick cent... | D014158 | T045 |
34,685,764 | neurogen potenti kda mitochondri transloc protein tspo pluripot p stem cell kda transloc protein tspo key mitochondri target differ tspo ligand exert neuroprotect effect assay neurogen potenti tspo induc neuron differenti pluripot p stem cell vitro studi chang cell morpholog cell prolifer cell death cell cycl mitochond... | D055495 | T040 |
34,685,762 | microenviron role mycosi fungoid szari syndrom progress therapeut implic mycosi fungoid mf sezari syndrom ss common cutan cell lymphoma hypothes interact immun system cutan cell neoplast element may play role mfss pathogenesi progress | D018450;D059016 | T033;T070;T046 |
34,685,759 | foxdl negat regul chordin transcript neuroectoderm xenopus gastrula inhibit bone morphogenet protein bmps primari step toward neuroectoderm format vertebr process spemann organ dorsal mesoderm play decis role secret sever extracellular bmp inhibitor chordin chrd chrd physic interact bmp protein inhibit bmp signal trigg... | D018507;D014158 | T045 |
34,685,755 | mitochondri phospholipid homeostasi regul aaa proteas paiap affect organism age mitochondria ubiquit organell eukaryot organ number essenti function includ synthesi iron sulfur cluster amino acid lipid adenosin triphosph atp age fungal age model podospora anserina inner mitochondri membran imm undergo promin morpholog ... | D006706 | T038 |
34,685,753 | chemic genet screen drosophila germlin uncov small molecul drug sensit stem cell insult induc apoptosi cancer stem cell contrast differenti daughter cell endur genotox insult escap apoptosi caus tumor recurr understand normal adult stem cell surviv go quiescenc may help identifi druggabl pathway cancer stem cell co opt... | D005820 | T059;T060 |
34,685,752 | structur equat model sem analysi sequenc variat green plant regener via anther cultur barley process anther cultur involv numer abiot stress requir cellular reprogram microspor development switch plant regener stress affect dna methyl pattern sequenc variat number green plant regener recent barley hordeum vulgar l medi... | D014644;D008954;D046509 | T070;T059;T075 |
34,685,751 | involv autophagi age chronic cholestat diseas autophagi housekeep lysosom degrad process involv numer physiolog patholog process eukaryot cell dysregul hepat autophagi describ sever condit obes diabet cholestat diseas review role autophagi focus age relat cholestat diseas discuss therapeut potenti molecular target iden... | D001343 | T043 |
34,685,750 | effect fibrot cell type densiti atrial fibril dynam silico studi remodel atrial fibril af underlin electr structur chang atria fibrosi hallmark arrhythmogen structur alter fibrosi import featur af substrat lead abnorm conduct consequ mechan dysfunct fibrot process compris presenc fibrot cell includ fibroblast myofibrob... | D003198 | T066 |
34,685,748 | function proteom profil tripl negat breast cancer tripl negat breast cancer tnbc subtyp breast cancer compris various diseas entiti share set common featur lack express estrogen receptor progesteron receptor human epiderm growth factor receptor respect receptor status convent chemotherapi remain main therapeut option t... | D040901 | T091 |
34,685,747 | electr ventricular remodel dilat cardiomyopathi ventricular arrhythmia contribut signific morbid mortal patient heart failur hf pathomechan under arrhythmogen patient structur heart diseas impair cardiac function includ myocardi fibrosi remodel ion channel affect electrophysiolog properti ventricular cardiomyocyt dysre... | D055724;D020257 | T040;T042 |
34,685,745 | sildenafil mediat neuroprotect adult neonat brain injuri evid mechan futur translat cerebr stroke traumat brain injuri hypox ischem encephalopathi among frequent occur brain injuri complex pathogenesi character synergist interact alter cerebrovascular system cell death inflamm basi brain damag lead behavior neurodevelo... | D000066829;D057170 | T043;T062 |
34,685,742 | integr analysi identifi gene associ stem immun infiltr glioblastoma imper identifi mechan confer stem cancer cell effect target moreov mani studi link stem characterist immun respons tumour therefor current studi involv gbm start studi birc one rare gene differenti express normal cancer cell cxcr gene involv surviv pro... | D052138 | T028 |
34,685,738 | evalu intern societi cutan lymphoma algorithm diagnosi earli mycosi fungoid intern societi cutan lymphoma iscl propos diagnost algorithm earli mycosi fungoid mf includ clinic histolog immunophenotyp molecular criteria analyz immunolog marker featur cell clonal earli mf case non mf case valid iscl algorithm found cd cd ... | D000465;D038622;D012955 | T064;T170;T094;T067;T078 |
34,685,737 | novel balanc mechan particip stem cell therapi allevi neuropatholog cognit impair anim model alzheim diseas stem cell therapi improv memori loss cognit deficit anim model alzheim diseas under mechan remain determin may involv interact stem cell hippocamp cell transplant stem cell alter patholog state establish novel ba... | D033581 | T061 |
34,685,735 | quantifi renin angiotensin system alter covid renin angiotensin system ras play pivot role wide seri physiolog process among inflamm blood pressur regul one key compon angiotensin convert enzym identifi entri point sar cov virus host cell therefor lot research devot studi ras dysregul covid discuss alter regulatori ras... | D012084 | T022 |
34,685,734 | autophagi lysosom system cancer autophagi lysosom system togeth refer autophagolysosom system cellular qualiti control network maintain cellular health homeostasi remov cellular wast includ protein aggreg damag organell invad pathogen autophagolysosom system role varieti pathophysiolog disord includ cancer neurolog dis... | D001343 | T043 |
34,685,732 | restor cell cycl prolifer compet termin differenti skelet muscl myotub termin differenti ill defin insuffici character nonprolifer state although classic deem irrevers clear least sever termin differenti td cell type brought back cell cycl strive uncov molecular base termin differenti whose fundament understand goal ad... | D002453;D002454 | T043 |
34,685,730 | origin isoform specif function exchang protein direct activ camp phylogenet analysi exchang protein direct activ camp epac epac one sever famili cellular effector prototyp second messeng camp understand origin molecular evolut epac protein perform comprehens phylogenet analysi epac epac studi demonstr unlik cousin pka ... | D010802 | T062;T078 |
34,685,728 | kynaahr signal suppress neural stem cell plastic neurogenesi adult zebrafish model alzheim diseas neurogenesi decreas alzheim diseas ad patient suggest restor normal neurogen respons could diseas modifi intervent studi mechan patholog induc neuro regener vertebr brain zebrafish excel model due extens neural regener cap... | D055495;D009473 | T040;T042;T043 |
34,685,727 | modul inher nich multicellular msc spheroid reconfigur metabol enhanc therapeut potenti multicellular spheroid show three dimension organ extens cell cell cell extracellular matrix interact owe nativ tissu mimick characterist mesenchym stem cell msc spheroid consid promis implant therapeut stem cell therapi herein aim ... | D056747;D045164;D055153 | T022;T061 |
34,685,726 | direct differenti human pluripot stem cell toward skelet myogen progenitor purif use surfac marker advanc reprogram somat cell induc pluripot stem cell ipsc provid strong framework vitro diseas model gene correct stem cell base regen medicin case skelet muscl disord ipsc use generat skelet muscl progenitor studi diseas... | D002454;D024510 | T043;T042 |
34,685,725 | model hypox stress vitro use human embryon stem cell deriv cardiomyocyt matur fgf ascorb acid treatment matur cardiomyocyt cms obtain human pluripot stem cell hpscs requir accur vitro model adult onset cardiac diseas drug discoveri found fgf ascorb acid aa induc differenti bg human embryon stem cell cardiogen mesoderm ... | D002454;D008954;D013312 | T121;T043;T039;T046;T032;T075;T040 |
34,685,724 | bcep web server predict linear b cell epitop enhanc immunogen cross reactiv predict linear b cell epitop interest product antigen specif antibodi design peptid base vaccin present bcep web server predict linear b cell epitop tailor select epitop immunogen capabl induc cross reactiv antibodi nativ antigen bcep implement... | D016208;D000086402 | T170;T005 |
34,685,723 | unzip secret amyloid disassembl human disaggregas neurodegen diseas nds increas posit lead caus global death acceler age popul strong relationship neurodegener forecast patholog huge global health problem upcom year scenario urgent need understand basic molecular mechan associ diseas major molecular hallmark nds accumu... | D066329 | T116 |
34,685,722 | comparison differenti pattern wntshh signal pluripot stem cell cultur differ condit pluripot stem cell pscs character abil self renew well undergo multidirect differenti cultur condit pivot influenc differenti pattern current studi compar fate mous pscs use two cultur media chemic defin free anim reagent standard one r... | D002454;D060449 | T043;T044 |
34,685,721 | regulatori activ noncod rnas ilc innat lymphoid cell ilc innat lymphocyt play essenti function protect microbi infect particip homeostat patholog context includ tissu remodel cancer inflammatori disord number lineag defin transcript factor concur establish transcript network determin ident activ distinct ilc subset how... | D005786 | T045 |
34,685,718 | sirtuin interest player cours hiv infect comorbid sirtuin sirt famili enzym group nad depend deacetylas reaction split acetyl group various transcript factor histon regul mani process organ activ sirtuin link metabol control oxid stress inflamm apoptosi also affect cours viral infect reason may particip pathogenesi dev... | D015897 | T033 |
34,685,715 | protein compon neutrophil extracellular trap arrest cell wall protein candida albican fungal infect use host invas one defens mechan human immun system counteract infect opportunist fungal pathogen candida albican recruit neutrophil site invas subsequ product neutrophil extracellular trap net effici captur kill invad c... | D054884 | T040 |
34,685,714 | sirna nanoparticl target pd l activ tumor immun abrog pancreat cancer growth human preclin model pancreat cancer character late detect frequent drug resist high metastat natur lead poor prognosi antibodi base immunotherapi show limit success pancreat cancer part owe low deliveri rate drug tumor herein describ poli lact... | D007109 | T042 |
34,685,712 | activ mtorc free fatti acid suppress lamp autophagi function via er stress alcohol relat liver diseas alcohol relat liver diseas ald character accumul hepat free fatti acid ffas liver injuri present studi aim investig mechanist target rapamycin complex mtorc play role ffa induc organell dysfunct therebi contribut devel... | D001343;D059865 | T043;T049 |
34,685,711 | chaperon mediat autophagi marker lampa hspa advanc non small cell lung cancer neoadjuv therapi recent year autophagi attract attent research mani medic field includ cancer research certain anti macroautophagi drug combin cytotox target therapi enter clinic trial present studi focus less explor subtyp autophagi ie chape... | D000080642;D020360 | T043;T061 |
34,685,710 | cullin e ubiquitin ligas regul male gonocyt migrat prolifer blood testi barrier homeostasi ubiquitin essenti posttransl modif play fundament role mammalian spermatogenesi previous report requir two cullin ubiquitin ligas famili gene cullin cula cullin b culb murin spermatogenesi gene requir male fertil despit distinct ... | D002465 | T043 |
34,685,705 | role mir p regul cfl myogen differenti cc myoblast skelet myogenesi requir maintain muscl mass integr impair myogenesi causal link etiolog muscl wast recent shown excess uptak satur fatti acid sfa play signific role pathogenesi muscl wast although microrna mirna implic regul myogenesi molecular mechan wherebi sfa induc... | D005786 | T045 |
34,685,704 | ledgfp integras bind domain interactom contribut surviv clonogen tumorspher format docetaxel resist prostat cancer cell patient prostat cancer pca receiv docetaxel chemotherapi invari develop chemoresist transcript co activ len epithelium deriv growth factor p ledgfp also known dfs psip upregul sever human cancer inclu... | D019008 | T042;T038 |
34,685,703 | iqsec defici result abnorm social behavior relev autism affect function neural circuit medial prefront cortex iqsec guanin nucleotid exchang factor gef adp ribosyl factor arf protein exclus local postsynapt densiti excitatori synaps human genom studi reveal iqsec gene associ x link neurodevelopment disord intellectu di... | D012919 | T054 |
34,685,700 | alveolar macrophag adapt anatom nich inflamm earli stage life develop alveoli colon embryon macrophag becom resid alveolar macrophag resam self sustain local divis genet epigenet signatur extent function resam dictat lung microenviron use cytokin ligand receptor interact stroma cell orchestr lung homeostasi rest condit... | D000222 | T040 |
34,685,699 | cycloastragenol triterpenoid saponin regul oxid stress neurotroph dysfunct neuroinflamm apoptot cell death neurodegen condit unveil effect cycloastragenol amyloid beta induc oxid stress neurogen dysfunct activ mitogen activ protein map kinas mitochondri apoptosi induc mous model alzheim diseas ad induc mous model devel... | D017209;D018384 | T043;T116;T049;T123 |
34,685,698 | identif tropic plant extract extend yeast chronolog life span certain plant extract pes contain bioactiv compound antioxid lifespan extend activ organ pes play differ role cellular process enhanc stress resist modul longev defin signal pathway contribut longev report discoveri pes extend chronolog life span cls bud yea... | D014329 | T070 |
34,685,697 | effect periop lipid status clinic outcom cardiac surgeri patient undergo cardiac surgeri increas cardiovascular risk includ alter lipid status howev data effect cardiac surgeri cardiopulmonari bypass cpb plasma level key lipid scarc investig potenti effect cpb plasma lipid level associ earli postop clinic outcom prospe... | D006348;D019990 | T058;T061 |
34,685,696 | vaccin covid prioriti mrna base formul septemb twenti one anti covid vaccin approv world util expedit end current pandem besid usual vaccin format includ inactiv virus eight approv vaccin protein base vaccin four approv vaccin three new format valid recombin adenovirus six approv vaccin dna one approv vaccin messeng rn... | D012333;D000086402 | T114;T005;T123 |
34,685,695 | recent therapeut approach modul hippo pathway oncolog regen medicin hippo pathway evolutionari conserv signal network regul essenti process organ size cell prolifer migrat stem apoptosi alter pathway common found solid tumor lead hyperprolifer resist chemotherapi compens mkras tumor immun evas termin effector hippo pat... | D008495;D044968;D015398 | T091;T044;T043 |
34,685,693 | ischemia reperfus injuri simul lung transplant set differenti regul transcriptom profil human lung endotheli epitheli cell current understand mechan ischemia reperfus induc lung injuri lung preserv transplant main base clinic observ anim studi herein use cell system biolog approach explor mechan transcriptom level espe... | D020869;D016040 | T059;T063;T061 |
34,685,691 | szt interactom unravel new function kicstor complex seizur threshold szt compon kicstor complex catabol condit function negat regul amino acid sens branch mtorc mutat gene caus sever neurodevelopment epilept encephalopathi whose main symptom includ epilepsi intellectu disabl macrocephali szt remain one least character ... | D060066 | T169 |
34,685,688 | magnet guid perman magnet concept realize applic nanoparticl cell idea remot magnet guid develop under physic concept allow biject forc generat inner volum magnet system concept equal implement electro perman magnet perman magnet focus offer mani advantag equat magnet field forc well veloc deriv detail physic limit dis... | D060328;D059346 | T070;T074;T073 |
34,685,687 | cisplatin reduc frequenc radiotherapi induc micronuclei peripher blood lymphocyt patient gynaecolog cancer possibl implic risk second malign neoplasm gynaecolog cancer common among women treatment includ surgeri radiotherapi chemotherapi last two method induc dna damag non target cell like peripher blood lymphocyt pbl ... | D048629 | T026 |
34,685,685 | biochemistri pathophysiolog regul linear ubiquitin intric regul coordin function associ ligas deubiquitinas ubiquitin system modul protein function decor target protein ubiquitin chain case sever type ubiquitin chain exist chain type determin mode regul conjug protein lubac ubiquitin ligas complex specif generat n term... | D054875 | T044 |
34,685,684 | apoptot cell trigger calcium entri phagocyt induc orai stim associ swift continu phagocytosi apoptot cell achiev modul calcium flux phagocyt howev molecular mechan apoptot cell modul calcium flux phagocyt incomplet understood use biophys biochem pharmaceut genet approach show apoptot cell induc orai stim interact lead ... | D017209 | T043;T116;T123 |
34,685,683 | transcriptom biomark tuberculosi valid npc singl mrna biomark diagnos tb predict diseas progress monitor treatment respons extern valid differ cohort key step translat develop new biomark previous describ three host mrna whose express peripher blood signific higher npc lower dock epha individu tb compar latent tb infec... | D018450 | T033;T046 |
34,685,682 | lineag select disturb earli human hematopoiet progenitor cell differenti common use plastic di ethylhexyl phthalat via reactiv oxygen speci fatti acid oxid make differ exposur ubiquit endocrin disrupt chemic edc major public health concern analyz physiolog impact edc di ethylhexyl phthalat dehp found metabolit mono eth... | D002454;D019070 | T043;T078 |
34,685,681 | enhanc express microrna g p contribut alzheim diseas pathogenesi regul express mitochondri gene alzheim diseas ad common form dementia elder popul under caus fulli elucid recent studi shown microrna mirna play import role regul express level gene associ ad develop studi analyz mirna plasma cerebrospin fluid csf ad pati... | D005786;D050259 | T028;T045 |
34,685,680 | map proxim interact network stim reveal new mechan cytoskelet regul stromal interact molecul stim resid primarili sarcoendoplasm reticulum sens intralumin ca level activ orai channel plasma membran initi ca influx previous shown stim involv dynam remodel actin cytoskeleton howev downstream effector stim lead cytoskelet... | D025941;D060066 | T169;T063 |
34,685,679 | complex metabol network confer immunosuppress function myeloid deriv suppressor cell mdscs within tumour microenviron myeloid deriv suppressor cell mdscs constitut plastic heterogen cell popul among immun cell within tumour microenviron tme support cancer progress resist therapi tumour progress cancer cell modifi metab... | D007165;D053858 | T044;T169;T061 |
34,685,678 | har power induc pluripot stem cell gene edit technolog therapeut implic hematolog malign vitro model hematolog malign provid insight influenc genet aberr cellular molecular mechan involv diseas progress also aid develop evalu therapeut agent owe self renew differenti capac induc pluripot stem cell ipsc emerg potenti so... | D000072669 | T063 |
34,685,674 | integr cghwes analys advanc understand aggress neuroblastoma evolut case studi neuroblastoma nb common extra cranial malign preschool children portray genet landscap over aggress nb lead rapid clinic progress diseas tumor dna collect pre post treatment analyz array compar genom hybrid acgh whole exom sequenc wes pharma... | D055028;D000073359 | T063 |
34,685,673 | matern b cell intrins myd signal mediat lps driven intrauterin fetal death immunolog network balanc toler toward patern alloantigen pregnanc normal immun respons pathogen subclin infect impact balanc lead preterm birth even intrauterin fetal death iufd recent show loss matern b cell render murin fetus suscept iufd lps ... | D015398 | T043;T044 |
34,685,672 | nematostella vectensi emerg model deciph molecular cellular mechan under whole bodi regener capac regener lost injur bodi part widespread featur within metazoan intrigu scientist centuri one extrem type regener call whole bodi regen capac enabl regener fulli function organ isol bodi part exclus habitat whole bodi regen... | D023421 | T008 |
34,685,670 | myricetin galactopyranosid exhibit potenti anti osteoporot properti human bone marrow deriv mesenchym stromal cell via stimul osteoblastogenesi suppress adipogenesi natur bioactiv substanc promis lead compound benefici effect various health problem includ osteoporosi context goal studi investig effect myricetin galacto... | D050156;D010012 | T044;T042 |
34,685,668 | loganin amelior pain diabet neuropathi modul oxid stress inflamm insulin sensit streptozotocin nicotinamid induc diabet rat loganin iridoid glycosid antioxid anti inflammatori glucos lower activ may address patholog mechan pain diabet neuropathi pdn relat inflamm oxid stress hyperglycemia studi investig under mechan ac... | D007333;D018384 | T049;T046 |
34,685,667 | clinic applic cell scaffold construct bone regener therapi bone tissu engin bte process combin live osteoblast progenitor biocompat scaffold produc biolog substitut integr host bone tissu recov function mesenchym stem cell mscs research post natal stem cell self renew properti multi differenti capac give rise various c... | D023822 | T061 |
34,685,661 | stem cell research tool human metabol disord overview metabol disord common popul worldwid among diseas highest health util cost per person despit ongo effort develop new treatment current mani disord approv therapi result huge econom hit tension societi review recapitul recent advanc stem cell gene therapi potenti too... | D057905 | T062 |
34,685,658 | analysi gene express pattern epigenet enzym dnmta tet ogt murin chondrogen model investig gene express pattern select enzym involv dna methyl effect dna methyl inhibitor azacytidin vitro vivo cartilag format base data pcr array perform chondrifi bmp overexpress cht cell relat express tet tet methylcytosin dioxygenas dn... | D044127 | T045 |
34,685,657 | integu specif transcript regul mid stage flax seed develop influenc releas mucilag seed oil content flax linum usitatissimum l seed oil accumul embryo mucilag synthes seed coat great econom import food pharmaceut well chemic industri theori link oil mucilag product seed consist spatio tempor competit compound photosynt... | D018507;D018506;D014158 | T045 |
34,685,655 | mechan stem cell therapi spinal cord injuri everi year million peopl worldwid suffer spinal cord injuri sci irretriev sequela rehabilit current avail treatment restor damag tissu therefor function recoveri patient remain limit pathophysiolog spinal cord injuri heterogen impli potenti therapeut target differ depend time... | D033581 | T061 |
34,685,654 | inhibitori receptor gpr adgrg specif express tissu resid memori cell mice dispens differenti function vivo tissu resid memori rm cell potent antivir antibacteri function protect epitheli mucos surfac bodi infect pathogen strong proinflammatori activ rm cell suggest requir express inhibitori molecul restrain memori cell... | D007156 | T042 |
34,685,653 | silico evalu natur compound acid extracellular environ human breast cancer surviv rate breast cancer bc improv recent year resist metastasi recurr still remain major therapeut challeng bc acid tumor microenviron tme attract attent associ tumorigenesi metastasi drug resist immun surveil studi evalu natur compound tradit... | D003198 | T066 |
34,685,652 | autophagi tumor immun viral base immunotherapeut approach cancer autophagi fundament catabol process essenti mainten cellular tissu homeostasi well direct contribut control invad pathogen unsurpris process becom critic support cellular dysregul occur cancer particular tumor microenviron immun cell infiltr ultim play ro... | D001343;D007167 | T043;T061 |
34,685,649 | ikknf b activ astrocyt reduc amyloid deposit process associ specif microglia polar alzheim diseas ad common neurodegen diseas accompani pronounc neuroinflammatori respons main character mark microgliosi astrogliosi howev remain open differ aspect astrocyt microgli activ affect diseas progress previous found microglia e... | D016764 | T082 |
34,685,648 | integr proteom transcriptom analysi gonad reveal disrupt germ cell prolifer divis energi storag glycogen steril triploid pacif oyster crassostrea giga triploid oyster poor gonad develop bring higher econom benefit also potenti applic genet contain aquacultur howev key factor influenc germ cell develop triploid oyster r... | D004734;D020869;D040901;D057885 | T047;T039;T091;T040;T059;T063 |
34,685,647 | neutrophil extracellular trap dnase balanc autoimmun neutrophil extracellular trap net macromolecular structur program trap circul bacteria virus accumul net circul correl format anti doubl strand ds dna antibodi consid causat factor system lupus erythematosus sle digest dna dnase dnasesl rate limit factor net accumul ... | D015551 | T046 |
34,685,645 | prognost signific dysregul epigenom chromatin modifi cervic cancer broaden understand epigenom chromatin regul cervic cancer examin status signific set epigenom chromatin modifi cervic cancer use comput biolog observ epigenom andor chromatin regul differenti upregul human cancer includ upregul invas squamous cell carci... | D057890 | T091 |
34,685,644 | role insulin like growth factor igf control neuroendocrin regul growth mammal neuroendocrin system includ communic hypothalamus pituitari play major role control bodi growth cellular metabol gh produc pituitari somatotroph consid master regul somat develop involv direct indirect carbohydr lipid metabol via complex yet ... | D048788 | T040 |
34,685,643 | role extracellular vesicl cell death inflamm extracellular vesicl ev identifi novel mediat intercellular communic work via deliv sequest cargo cell close vicin well distant site bodi regul pathophysiolog process cell death inflamm biolog crucial process normal physiolog patholog process indistinguish link effector modu... | D017209;D016923;D000086402 | T043;T116;T005;T123 |
34,685,642 | review bioeffect static magnet field oral tissu deriv cell applic regen medicin magnet wide use dentistri orthodont tooth movement dentur retent nevertheless critic arisen regard biosafeti static magnet field smf effect surround tissu various controversi piec evid discuss regard smfs cellular biophys littl consensus re... | D060526;D044968 | T091;T070 |
34,685,641 | influenc age breed bovin ovarian capillari blood suppli ovarian mitochondria telomer length worldwid dairi cow type high produc cattl hpc suffer health fertil problem young age therefor lose product averag three lactat still contenti whether problem primarili due genet manag feed factor vascular play fundament role cyc... | D001947;D059505 | T040;T043;T045 |
34,685,638 | sp serin proteas gut microbiota influenc coliti drive intestin dysbiosi mice increas proteas activ link pathogenesi ibd studi focus host proteas gut inflamm remain unclear address potenti contribut bacteri counterpart present studi report function character newli identifi serin proteas sp human gut microbiota serin pro... | D000069196 | T007;T001 |
34,685,636 | oxysterol hydroxylas cypb attenu metabol associ fatti liver diseas mice thermoneutr ambient temperatur import determin altern bile acid synthesi pathway control oxysterol hydroxylas cypb progress metabol associ fatti liver diseas mafld investig whether cypb involv etiolog mafld condit low high energi expenditur cypb wi... | D013696 | T081 |
34,685,632 | usp oncogen tumor suppressor unifi paradigm squamous cell carcinoma squamous cell carcinoma therapeut challeng tumor entiti low respons rate radiotherapi chemotherapi common observ squamous patient accord mortal rate relat high compar tumor entiti recent target usp emerg potenti altern improv therapeut respons clinic o... | D016147;D009857 | T028 |
34,685,631 | oxytocin posit alloster modul opioid receptor opioid receptor g protein signal pathway oxytocin ot influenc various physiolog function uterin contract maternalsoci behavior analgesia opioid signal pathway involv one analges mechan ot previous show ot act posit alloster modul pam enhanc opioid receptor mor activ studi f... | D015398 | T043;T044 |
34,685,630 | cytogenet evid clarifi phylogeni famili rhynchocyclida ave passeriform phylogenet posit taxonom status rhynchocyclida ave passeriform subject debat sinc first descript model rhynchocyclida repres subfamili level taxon place within tyrant flycatch tyrannida consid classif includ cytotaxonom charact test hypothesi chromo... | D020732;D010802 | T062;T063;T078 |
34,685,629 | n myc downstream regul gene ndrg function posit regul apoptosi new insight ndrg tumor suppressor n myc downstream regul gene ndrg tumor suppressor gene increas tumor sensit anticanc drug slow tumor progress inhibit metastasi ndrg suppress various aggress tumor posit wherea ndrg express associ patient prognosi improv su... | D017209 | T043;T116;T123 |
34,685,626 | molecular basi domin sar cov spike deriv epitop present hla recognis public tcr data current avail immun system recognis sar cov virus grow rapid structur sar cov protein complex antibodi help us understand immun system abl recognis new virus howev lack data cell abl recognis virus cell especi cytotox cd cell critic vi... | D000086402 | T005 |
34,685,625 | adipos tissu deriv mesenchym stem cell mediat pd l overexpress white adipos tissu obes individu result cell dysfunct pd lpd immun checkpoint axi strongest cell exhaust induc immun dysfunct occur obes analyz impact obes pd lpd express white adipos tissu wat mice human white adipocyt found pd l overexpress wat diet induc... | D005786 | T045 |
34,685,624 | dysfunct glutam delta receptor cerebellin tran synapt signal central amygdala chronic pain chronic pain debilit condit involv neuron dysfunct synapt mechan under persist pain still poor understood found synapt organ glutam delta receptor glud express postsynapt parabrachio central laterocapsular amygdala pb celc glutam... | D015398 | T043;T044 |
34,685,623 | haskap berri phenol subclass differenti impact cellular stress sens primari immort dermal fibroblast general accept dietari phenol fruit signific import human health unfortun minim publish data differ phenol structur impact biolog pathway cellular molecular level observ haskap berri extract isol ethanol formic acid wat... | D013312 | T121;T039;T046;T032;T040 |
34,685,622 | pro surviv octstatmcl axi associ poor prognosi lung adenocarcinoma patient embryon stem cell marker oct express sever human cancer posit correl poor outcom cancer patient howev physiolog role cancer progress remain poor understood tumor cell block apoptosi escap cell death prolifer indefinit lead ineffect therapi cance... | D015398 | T043;T044 |
34,685,621 | metabol stress adapt underli mammari gland morphogenesi breast cancer progress breast cancer display dynam reprogram metabol activ cancer develop premalign lesion primari tumor metastas numer advanc focus tumor develop pro prolif metabol signal differ adjac non transform epitheli tissu lead target oncogen driven liabil... | D000222;D018450;D009024;D013312 | T121;T039;T046;T032;T040;T033 |
34,685,620 | bmp attenu inflamm induc pyroptosi improv cardiac repair diabet cardiomyopathi present studi investig novel signal target diabet cardiomyopathi inflamm induc caspas depend cell death pyroptosi involv nek gbp activ activ nlrp inflammasom destabil cardiac structur neovascular furthermor explor therapeut abil bone morphog... | D000069292 | T043 |
34,685,619 | cdk mediat phosphoryl bag promot mitot cell shape remodel molecular assembl mitot p bodi cochaperon bcl associ athanogen bag complex heat shock protein hspb facilit mitot round spindl orient proper absciss daughter cell bag hspb mitot function implic sequestosom psqstm suggest role protein qualiti control howev interpl... | D048430;D008938 | T043;T032 |
34,685,618 | new insight molecular mechan mediat adapt exercis review focus mitochondri biogenesi mitochondri function mitophagi autophagi exercis fundament good health practic regular confer myriad metabol benefit rang tissu benefit mediat rang adapt respons coordin multi organ manner continu understand molecular mechan action con... | D000222;D001343;D063306;D001678 | T040;T070;T043 |
34,685,617 | autophagi polar toward cell front migrat spatial perturb oncogen ras autophagi physiolog degrad process remov unnecessari dysfunct compon cell import normal cellular homeostasi respons varieti stress nutrient depriv defect autophagi link numer human diseas includ cancer cancer cell requir autophagi migrat invad studi i... | D001343;D002465;D011905;D009857 | T043;T028 |
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