PMID int64 27.8M 36.2M | Title/Abstract stringlengths 7 10.7k | MeshTerms stringlengths 7 104 | SemanticTypes stringlengths 4 84 |
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34,681,706 | structur dynam behaviour colloid compet interact confin slit pore system short rang attract long rang repuls interact form period modul phase low temperatur cluster crystal hexagon lamellar bicontinu gyroid phase period microphas stabl regardless physic origin interact howev yet experiment observ colloid system princip... | D056004 | T044;T066 |
34,681,705 | sigma receptor critic mitochondri activ unfold protein respons larval zebrafish sigma receptor sr high conserv transmembran protein high enrich mitochondria associ endoplasm reticulum er membran interact sever partner involv er mitochondria ca transfer activ er stress pathway mitochondria function character new sr defi... | D056811 | T043 |
34,681,704 | telomer like repeat flank sequenc retrotranscrib telomeras rna insert dna doubl strand break site vertebr genom evolut interstiti telomer sequenc itss stretch telomer like repeat locat intern chromosom site previous demonstr itss insert repair dna doubl strand break cours evolut rodent itss call terc itss flank fragmen... | D019143 | T038 |
34,681,703 | role mitochondria radiat respons epigenet metabol signal impact recent radiat effect consid main due nuclear dna damag manag repair mechan howev molecular biolog studi reveal outcom exposur ioniz radiat ir high depend activ regul molecular compon organell determin cell surviv prolifer capac typic epigenet regul organel... | D011839 | T070 |
34,681,702 | mine fiskebi iii mandarin ottawa express profil understand iron stress toler respons soybean soybean glycin max nbsp l merr genotyp fiskebi iii high resist multitud abiot stress includ iron defici incur mild yield loss stress condit convers mandarin ottawa high suscept diseas suffer sever phenotyp damag yield loss expo... | D040641;D013312 | T121;T039;T046;T032;T028;T040 |
34,681,700 | water activ predict sugar polyol system use theoret molecular descriptor water activ key factor develop pharmaceut cosmet food product aqueous solut nonelectrolyt norrish model provid simpl effect way evalu quantiti howev contain paramet known norrish constant must estim experiment data studi new strategi propos predic... | D008962 | T062;T170 |
34,681,697 | synthesi investig build block dibenzo b f oxepin use photopharmacolog synthesi photoswitch azo dibenzo b f oxepin deriv microtubul inhibitor describ subsequ examin reaction methoxi deriv nitrodibenzo b f oxepin differ aldehyd presenc bf oet catalyst studi provid concis method construct azo dibenzo b f oxepin skeleton a... | D008027;D015394;D010777 | T070;T085;T090 |
34,681,691 | proteom nucleotid profil tool biomark drug target discoveri proteom gone tremend develop recent decad | D055808;D040901 | T091;T062 |
34,681,690 | direct base excis repair mediat regul gc rich cis element respons formylcytosin carboxycytosin stepwis oxid epigenet mark methylcytosin base excis repair ber result formylcytosin fc carboxycytosin cac may provid mechan reactiv epigenet silenc gene howev function fc cac defin gene element scarc explor analyz express rep... | D018899;D004249;D004260;D011401 | T049;T114;T045;T123 |
34,681,688 | beginn introduct skin stem cell wound heal primari function skin physic barrier environ divers pathogen therefor integr essenti surviv skin regener depend multipl stem cell compart within epidermi despit differ transcript prolif capac well differ anatom locat fall general term skin stem cell sscs skin wound normal heal... | D012038;D014945 | T040;T042 |
34,681,687 | effect photobiomodul bone defect repair diabet rat model purpos studi examin prospect therapeut effect photobiomodul heal bone defect diabet mellitus dm use rat model provid basic knowledg photobiomodul therapi pbmt bone defect repair vitro studi alizzarin red stain assay use evalu effect pbmt osteogen differenti vivo ... | D001861;D028022;D010012 | T042;T061 |
34,681,686 | clomiphen citrat show effect sustain antimicrobi activ mycobacterium abscessus mycobacterium abscessus abscessus caus chronic pulmonari infect difficult non tubercul mycobacteria ntm treat due resist current antimicrobi drug treatment success rate thus novel treatment drug need identifi drug clomiphen citrat cc known t... | D008264 | T025 |
34,681,685 | il ecosystem head neck cancer possibl therapeut perspect interleukin il high potent cytokin involv multipl biolog process previous report play distinct role inflamm autoimmun psychiatr disord age various type cancer furthermor understood il signal pathway substanti player orchestr cancer microenviron thus appear potent... | D059016 | T070 |
34,681,684 | presurg studi curcumin combin anthocyanin supplement patient colorect adenomat polyp adenomat polyp precancer lesion associ higher risk colorect cancer crc curcumin anthocyanin shown promis crc prevent activ preclin epidemiolog studi object window opportun proof principl trial evalu effect curcumin combin anthocyanin s... | D019587 | T168;T061 |
34,681,683 | resvega nutraceut omega resveratrol supplement reduc angiogenesi preclin mous model choroid neovascular age relat macular degener amd eye diseas character damag central part retina macula affect million peopl worldwid advanc stage blind spot grow center vision sever handicap patient degen condit despit therapeut advanc... | D019587 | T168;T061 |
34,681,680 | supplement serum deriv extracellular vesicl reinforc antitumor immun induc cryo thermal therapi effect cancer therapi reshap immunosuppress trigger antitumor immun previous develop novel cryo thermal therapi appli local rapid cool follow rapid heat tumor tissu could ablat local tumor also subsequ induc system long term... | D017679;D000067128 | T026;T061 |
34,681,678 | anxa contain ev regul macrophag polar tumor microenviron promot pancreat cancer progress metastasi tumor microenviron tme dynam system nontumor cancer cell intercommun solubl factor extracellular vesicl ev tme pancreat cancer pc critic aggress annexin anxa identifi one oncogen element previous demonstr autocrineparacri... | D009389;D059016 | T070;T046 |
34,681,677 | select valid refer gene rt qpcr analysi aegilop tauschii coss differ abiot stress aegilop tauschii coss aggress serious annual grass weed china dd genom rich sourc genet materi perform better differ abiot stress condit salin drought temperatur etc revers transcrib quantit polymeras chain reaction rt qpcr reliabl techni... | D018506;D017343;D013312 | T121;T045;T039;T046;T032;T028;T040 |
34,681,675 | structur format mechan antimicrobi peptid temporin b l induc tubular membran protrus temporin famili antimicrobi peptid amp isol frog skin short weak charg high hydrophob execut bactericid activ differ way mani amp work investig morpholog chang planar bilay membran compos mix zwitterion anion phospholipid induc tempori... | D056004;D010743 | T044;T066;T109;T123 |
34,681,674 | femal mice selenocystein trna delet agrp neuron maintain leptin sensit resist weight gain high fat diet role essenti trace element selenium hypothalam physiolog begun come light recent year selenium use synthes famili protein particip redox reaction call selenoprotein contain selenocystein residu place cystein past stu... | D059305 | T061 |
34,681,672 | minispheroid tool ligament tissu engin self assembl techniqu spheroid dimens influenc cruciat ligamentocyt phenotyp spheroid cultur might stabil ligamentocyt phenotyp therefor phenotyp lapin cruciat ligamentocyt l cls minispheroid prepar either hang drop hd method use novel spheroid plate sp option methyl cellulos mc t... | D023822 | T061 |
34,681,669 | impact matur myocardi respons ischemia effect remot precondit male rat age attenu cardiac toler ischemiareperfus ir associ defect protect cell signal howev onset phenotyp complet investig studi aim compar chang respons ir effect remot ischem precondit ripc heart younger adult month matur adult month male wistar rat cha... | D019157 | T061 |
34,681,661 | comparison distinct host specif respons three solanacea host induc phytophthora infestan three solanacea host tshs tuberosum n benthamiana lycopersicum repres three major phylogenet clade solanacea plant infect phytophthora infestan caus late blight one devast diseas serious affect crop product howev detail regard diff... | D059467 | T086;T081 |
34,681,660 | blood base immun profil combin machin learn discrimin psoriat arthriti psoriasi patient psoriasi pso chronic inflammatori skin diseas pso patient develop psoriat arthriti psa lead irrevers joint damag earli detect psa pso patient crucial time treatment difficult dermatologist implement therefor aim find diseas specif i... | D000069550 | T066 |
34,681,653 | quantum artifici neural network approach deriv high predict qsar model blood brain barrier passag success passag blood brain barrier bbb essenti prerequisit drug molecul design act central nervous system logarithm blood brain partit logbb serv effect index molecular bbb permeabl use three dimension distribut molecular ... | D016571;D021281 | T170;T081 |
34,681,650 | discoveri lactoferrin stimul hadsc deriv ev secret proof enhanc result ev skin model extracellular vesicl ev secret hadsc low concentr make difficult util develop therapeut product overcom problem associ low concentr propos human lactoferrin hlf stimul secret hadsc deriv ev hlf report upregul intracellular ca known cap... | D008954 | T075 |
34,681,649 | mpapathwaytool user friend automat assign microbi communiti data metabol pathway taxonom function character microbi communiti divers environ human gut bioga plant multi omic method play ever import role research assign identifi gene transcript protein biolog pathway better understand function singl speci microbi commun... | D014584 | T170 |
34,681,641 | g quadruplex target fight virus updat g quadruplex gs noncanon nucleic acid structur involv regul key cellular process transcript replic sinc discoveri gs main investig role cancer target anticanc therapi recent explor presenc role gs viral genom led discoveri g regul key viral pathway context employ select g ligand he... | D054856 | T086 |
34,681,640 | atpa mutant aldosteron produc adenoma lead cell prolifer molecular mechan atpa mutat mediat cell prolifer tumorigenesi aldosteron produc adenoma apa elucid first investig whether apa associ atpa lr mutat stimul cell prolifer second aim clarifi molecular mechan atpa mutat mediat cell prolifer perform transcriptom analys... | D049109 | T043 |
34,681,639 | role mscs cell fusion tissu regener regen medicin concern investig therapeut agent use promot process regener injuri differ diseas mesenchym stemstrom cell mscs secretom includ extracellular vesicl ev great interest due role tissu regener immunomodulatori capac low immunogen far clinic studi conclus show conflict effic... | D002459;D044968 | T091;T059 |
34,681,635 | evolutionari histori chymas locus locus encod sever major hematopoiet serin proteas sever hematopoiet cell immun system store larg amount proteas cytoplasm granul absolut major proteas belong larg famili chymotrypsin relat serin proteas chymas locus one four loci encod granul associ serin proteas mammal chymas locus en... | D019143 | T038 |
34,681,626 | integr epigenet mechan non genotox carcinogen hazard assess focus dna methyl histon modif epigenet involv seri mechan entail histon dna coval modif non code rnas collect contribut program cell function differenti epigenet anomali dna mutat co driver cellular dysfunct includ carcinogenesi alter epigenet system occur can... | D019175;D057890 | T091;T044 |
34,681,618 | androgen receptor activ glioblastoma achiev ligand independ signal egfr potenti therapeut target androgen receptor ar ligand mediat transcript factor belong superfamili steroid receptor ar overexpress glioblastoma potenti therapeut target prostat breast cancer ar activ achiev also ligand independ signal receptor tyrosi... | D008024;D015398 | T043;T044;T103 |
34,681,617 | polycycl aromat hydrocarbon detect process meat caus genet chang colorect cancer polycycl aromat hydrocarbon pah common ingest via meat produc high temperatur cook meat pah potenti role carcinogenesi colorect cancer crc aim investig pah concentr eight type common consum readi eat meat sampl potenti effect gene express ... | D005786 | T045 |
34,681,615 | elucid carfilzomib induc cardiotox vivo model age prophylact potenti metformin carfilzomib first line proteasom inhibitor indic relapsedrefractori multipl myeloma mm clinic use hamper cardiotox phenomena previous establish translat model carfilzomib cardiotox young adult mice metformin emerg prophylact therapi consid m... | D000375 | T040;T033 |
34,681,604 | ampelopsin confer endur rehabilit mechan glycin max cv sowonkong multipl abiot stress present investig aim perceiv effect exogen ampelopsin treatment salin heavi metal damag soybean seedl glycin max l term physiochem molecular respons screen numer ampelopsin concentr soybean seedl growth indic concentr display increas ... | D013312 | T121;T039;T046;T032;T040 |
34,681,603 | ferroptosi crossroad gemcitabin resist tumorigenesi pancreat cancer overal five year surviv rate pancreat cancer hard chang past decad less resist known therapi includ chemotherapeut drug past decad gemcitabin forefront treatment pancreat ductal adenocarcinoma strategi combat drug resist need explor one promis possibl ... | D000079403 | T043 |
34,681,601 | cardiac telocyt year learn far close routin applic knowledg cardiovascular regen medicin regener diseas heart one princip challeng modern cardiovascular medicin ongo research stem cell base therapeut approach cell popul call telocyt tcs describ year ago larg contribut research area cardiovascular regener tcs cell small... | D044968 | T091 |
34,681,600 | exercis intervent mitig patholog liver chang nafld zebrafish activ sirtampknrf signal non alcohol fatti liver diseas nafld common diseas caus serious liver damag exercis recogn non pharmacolog tool improv patholog nafld howev antioxid effect mechan exercis amelior nafld remain unclear present studi conduct exercis trai... | D015398 | T043;T044 |
34,681,599 | systemat approach molecular dynam studi parametris gemini type cation surfact spread antibiot resist bacteria strain one serious problem medicin struggl nowaday trigger develop altern antimicrobi agent recent year one group gemini surfact massiv synthesis various structur configur obtain effect antibacteri properti unf... | D056004 | T044;T066 |
34,681,597 | enzym replac therapi pabinafusp alfa neuronopath mucopolysaccharidosi ii integr analysi preclin clinic data enzym replac therapi ert improv somat manifest mucopolysaccharidos mps howev intraven administ enzym cross blood brain barrier bbb ert ineffect progress neurodegener result sever central nervous system cns sympto... | D056947 | T061 |
34,681,589 | quantit estim index earli stage screen compound target protein protein interact drug like quantif use screen drug candid quantit estim drug like qed common use assess quantit drug efficaci suitabl screen compound target protein protein interact ppis recent gain attent therefor develop quantit estim index compound targe... | D060066 | T169 |
34,681,584 | molecular mechan food deriv polyphenol pd l dimer molecular dynam simul studi cancer immunotherapi emerg approach block interact program cell death pd program cell death ligand pd l use small molecul inhibitor food deriv polyphenol curcumin cc resveratrol rsv epigallocatechin gallat egcg anticanc immunolog function rec... | D056004 | T044;T066 |
34,681,583 | k ras act critic regul cd promot invas stem gbm respons ioniz radiat radiat therapi current standard care treatment use wide gbm patient howev radiat therapi still remain signific barrier get success outcom due therapeut resist tumor recurr understand under mechan resist recurr would provid effici approach improv thera... | D011839 | T070 |
34,681,581 | ampk local key differenti energi regul central node nutrit signal input metabol pathway amp activ protein kinas ampk tight regul maintain energi homeostasi subcellular compartment ampk one critic regul enabl ampk access proper target generat appropri respons specif perturb differ level stress one character local mechan... | D004734 | T040;T039 |
34,681,578 | photoactivat nanocrisprca system base crrna revers immobil carbon nanoparticl propos new approach engin photoactivat crisprca gene edit system novel nanocrisprca system base use auxiliari photocleav oligodeoxyribonucleotid pc dnas complementari crrna pc dnas contain three uv sensit linker made nitrophenyl ethanediol in... | D064113 | T040 |
34,681,570 | associ ovarian teratoma anti n methyl aspart receptor enceph updat integr review ovarian teratoma far common ovarian germ cell tumor teratoma benign unless somat transform occur design teratoma refer neoplasm differenti toward somat type cell popul recent research show strike associ ovarian teratoma anti n methyl aspar... | D015398 | T043;T044 |
34,681,569 | amala analysi direct evolut experi via anneal mutat approxim landscap present anneal mutat approxim landscap amala new method infer fit landscap direct evolut experi sequenc data experi typic start singl wild type sequenc undergo darwinian vitro evolut via multipl round mutat select target phenotyp last year direct evo... | D009154 | T045 |
34,681,565 | effect manganes genom integr multicellular model organ caenorhabd elegan although manganes mn essenti trace element overexposur associ mn induc toxic neurolog dysfunct even though mn induc oxid stress discuss extens neither under mechan potenti consequ mn induc oxid stress dna damag dna repair possibl result toxic char... | D004249 | T049 |
34,681,041 | associ gene gene interact studi late onset alzheim diseas russian popul alzheim diseas ad neurodegen disord repres common caus dementia studi perform sever differ analys detect loci involv develop late onset ad russian popul dna sampl unrel subject genotyp snps use iplex assay real time pcr identifi five genet loci sig... | D056726;D020022 | T033;T032;T063 |
34,681,040 | fa nf function annot pipelin protein non model organ implement nextflow function annot allow ad biolog relev inform predict featur genom sequenc therefor import procedur de novo genom sequenc project also use proofread improv gene structur annot introduc fa nf pipelin implement nextflow versatil comput workflow manag e... | D012984 | T170;T073;T090 |
34,681,038 | genet predict type diabet mellitus liabil glycat hemoglobin cardiovascular diseas wide angl mendelian random studi aim investig causal effect tdm liabil glycat haemoglobin hbac level various cardiovascular diseas outcom general popul non diabet individu specif method select variant genet instrument tdm liabil variant h... | D020022 | T032 |
34,681,037 | mitochondri stroke diagnost challeng chameleon mitochondri stroke like episod sles hallmark mitochondri encephalomyopathi lactic acidosi stroke like episod mela suspect anyon acutesubacut onset focal neurolog symptom age usual driven seizur suggest featur under mitochondri patholog includ evolv mri lesion often origin ... | D003937 | T060 |
34,681,036 | associ pipka polymorph alcohol use disord alcohol use disord aud influenc individu famili also last social impact communiti nation level dopaminerg neurotransmiss involv excess alcohol consumpt phosphatidylinositol phosphat kinas type pipka play import role regul ascend dopamin pathway studi determin possibl associ nin... | D020022;D055106 | T032;T063 |
34,681,035 | evalu associ comt rs polymorph swimmer competit perform swimmer competit perform result complic interact physiolog biochem physic psycholog factor strong affect water recent great attent paid role genet factor catechol methyltransferas gene comt influenc motiv emot stress toler self control sleep regul pain process per... | D056352 | T097;T098 |
34,681,034 | singl cell rna seq reveal gene express pattern vitro matur donkey oocyt donkey import domest anim provid labor meat milk medicin materi human howev donkey popul continu declin even risk extinct applic modern anim product technolog oocyt vitro matur promis method improv donkey popul studi explor gene express pattern don... | D059471;D059010 | T059;T061 |
34,681,033 | atyp nf microdelet challeng opportun genotypephenotyp correl patient larg nf delet patient neurofibromatosi type nf type nf delet often exhibit sever clinic manifest patient intragen nf gene mutat includ facial dysmorph featur overgrowth sever global development delay sever autist symptom consider reduc cognit abil det... | D017353 | T045 |
34,681,031 | generaliz gwa identifi genet risk variant metabol trait popul arabian peninsula arabian peninsula locat nexus africa europ asia implic earli human migrat arab popul character consanguin endogami lead inbreed global genom wide associ gwa studi metabol trait repres arab popul replic gwa identifi associ signal arab popul ... | D020022;D005828;D055106 | T032;T063;T090 |
34,681,023 | high dimension singl cell transcriptom melanoma cancer immunotherapi recent advanc singl cell transcriptom great improv knowledg complex transcript program rapid expand knowledg cellular phenotyp function within tumour microenviron immun system sever new singl cell technolog develop recent year enabl expand understand ... | D007167 | T061 |
34,681,022 | lineag specif gene famili expans dictyostelid genom display express bias evolutionari diversif develop gene duplic generat new gene contribut express chang evolut new function genom often consist gene famili undergo expans occur specif lineag reflect recent adapt diversif studi lineag specif gene gene famili expans stu... | D019143;D010802 | T062;T038;T078 |
34,681,020 | prenat diagnosi combin matern q interstiti delet patern q microdupl q delet syndrom well known rare genet condit caus partial termin interstiti delet long arm q chromosom phenotyp syndrom show broad spectrum clinic manifest due great variabl size locat delet literatur most termin delet chromosom q relat phenotyp descri... | D002869;D002872;D011296 | T049;T060 |
34,681,019 | wdr associ neurodegener case report highlight possibl mechan normal tension glaucoma wdr one number gene implic pathogenesi adult onset primari open angl glaucoma poag describ detail phenotyp patient pathogen variat wdr present protract histori central vision loss exam visual acuiti level tritan color defect show centr... | D020022 | T032 |
34,681,018 | structur protein analysi driver gene mutat conjunctiv melanoma recent year tremend enthusiasm respect detail genet basi mani neoplasm includ conjunctiv melanoma cm aim analyz five protein associ cm name braf nras c kit nf pten evalu protein intrins disord protein region idpr protein protein interact ppi predictor natur... | D011487 | T082 |
34,681,017 | preval clinic characterist hear loss caus myh variant variant myh report caus autosom domin nonsyndrom hereditari hear loss adnshl variant report caus hear loss various ethnic group howev avail inform preval well regard clinic featur remain fragmentari studi genet screen myh variant carri use larg seri japanes hear los... | D020022 | T032 |
34,681,016 | associ cypc promot hypomethyl small vessel occlus korean subject risk factor stroke fatal diseas includ type two diabet hypertens genet influenc small vessel occlus svo affect epigenet alter associ svo methyl cytochrom p famili subfamili c member cypc identifi studi measur level dna methyl cypc promot untransl region n... | D019175;D011401 | T044;T114;T123 |
34,681,015 | detect spinal muscular atrophi patient use dri saliva spot spinal muscular atrophi sma lower motor neuron diseas consid incur main symptom muscl weak muscular atrophi case sma caus homozyg delet surviv motor neuron smn emerg treatment splice modul smn smn gene replac therapi improv prognos motor function patient howev ... | D012463 | T031 |
34,681,014 | role glutathion mediat abscis acid signal regul seed dormanc drought toler plant growth develop interact environ regul phytohormon signal molecul evolut plant develop strategi effici signal percept activ signal transduct cascad maintain proper growth develop particular advers environment condit abscis acid aba one phyt... | D000222;D055864 | T040;T070 |
34,681,013 | moggi popul genet analysi unit kingdom non pedigre cat domest cat one popular pet world estim domest cat uk non pedigre domest shorthair dsh domest longhair dlh domest semi longhair cat dslh despit popular littl known uk non pedigre cat popul structur breed dynam use custom design singl nucleotid variant snv array stud... | D005828 | T090 |
34,681,012 | two year clinic descript patient rare type low ggt cholestasi caus novel variant usp report novel truncat mutat ubiquitin specif peptidas gene usp caus low gt ggt cholestasi genet test carri includ clinic exom sequenc proband sanger sequenc proband parent proband harbor novel cdel p cystrpfster mutat ubiquitin carboxyl... | D009154 | T045 |
34,681,009 | epigenet regulatori dynam model methamphetamin use disord methamphetamin meth use disord mud serious potenti lethal biopsychosoci diseas exposur meth caus long term chang brain region involv reward process motiv lead vulner individu engag patholog drug seek drug take behavior remain lifelong struggl crucial elucid unde... | D044127 | T045 |
34,681,007 | genet loci under awn morpholog barley barley awn high activ photosynthesi account grain weight barley divers length rang long awnless shape straight hood crook divers import intrigu geneticist sever decad larg collect awn mutant avail dozen map chromosom recent clone differ awn gene interact produc divers awn phenotyp ... | D017343 | T028 |
34,681,006 | genet genom reproduct medicin rapid innov meant reproduct medicin today repres clear exampl complex essenti adapt clinic practic laboratori techniqu new knowledg context dynam evolut medicin | D018456 | T091 |
34,681,005 | flt mutat associ segment lymphat dysfunct initi lymphat aplasia patient milroy diseas studi explor mutat fms relat tyrosin kinas vascular endotheli growth factor receptor gene flt lymphat defect patient milroy diseas md twenti nine patient lower limb lymphedema enrol sixteen patient famili histori md patient exhibit sp... | D020022 | T032 |
34,681,003 | methanogenesi salt toler gene novel halophil methanosarcinacea metagenom assembl genom former solar saltern anaerob archaeal methanogen key player global carbon cycl due role final stage organ matter decomposit anaerob environ wetland sediment present first draft metagenom assembl genom mag sequenc unclassifi methanosa... | D017753 | T070;T082 |
34,681,002 | associ genet express gene involv hpa axi suicid behavior systemat review suicid behavior sb high associ respons stress hypothalam pituitari adren hpa axi aim studi summar result obtain genet studi analyz hpa axi stress pathway sb systemat review | D056726 | T033;T063 |
34,681,001 | investig role common rare variant larg italian multiplex famili multipl sclerosi patient known multipl sclerosi ms suscept variant explain half diseas estim herit wherea low frequenc rare variant may part account miss herit thus sought determin occurr rare function variant larg italian ms multiplex famili five affect m... | D020022 | T032 |
34,681,000 | modul global gene express aneuploidi cnv dosag sensit regulatori gene aneuploidi disrupt genet balanc due partial genom dosag chang usual detriment euploidi variat investig modul gene express aneuploidi analyz transcriptom sequenc data autosom sex chromosom trisomi drosophila result show gene vari chromosom cis present... | D004303 | T045 |
34,680,999 | autism spectrum disord analysi mobil element q william beuren region compar genom autism spectrum disord asd group complex neurodevelopment disord character deficit social interact communic mani genet variant associ asd includ duplic q encompass gene symmetr hemizyg delet q caus william beuren syndrom wbs multisystem d... | D002872 | T049 |
34,680,997 | genet epigenet chang plant respons abiot stress current global climat crisi led drought high salin abnormaltemperatur heat cold serious threat crop product nbsp | D055864;D013312 | T121;T039;T046;T032;T040;T070 |
34,680,996 | metabolom crop breed general consider develop new product varieti agricultur crop becom increas difficult task modern approach identif benefici allel use elit cultivar quantit trait loci qtl map marker assist select mas effect insuffici keep pace improv wheat crop metabolom power underutil approach assist crop breed re... | D055432;D000069600 | T091;T040 |
34,680,995 | impact abcg gene polymorph predisposit psoriasi psoriasi chronic inflammatori diseas caus interact genet environment factor evid show associ psoriasi co morbid includ cardiovascular diseas metabol syndrom hyperuricemia genom wide associ studi reveal abcg gene encod atp bind cassett g protein associ inflamm higher serum... | D056726;D020022 | T033;T032;T063 |
34,680,991 | herit de novo mutat oesophag atresia tracheoesophag fistula aetiolog tracheoesophag fistula tof congenit anomali caus unknown major patient oatof variabl featur mani often mono genet syndrom research use anim model target gene involv candid pathway often result tracheoesophag phenotyp howev limit overlap gene implic an... | D005817;D020022 | T091;T032;T061 |
34,680,990 | expand constel histon post translat modif epigenet landscap emerg nucleosom base chromatin structur accompani evolutionari transit prokaryot eukaryot scenario histon becam heart complex precis time coordin chromatin architectur function adapt respons environment influenc mean epigenet mechan notabl epigenet machineri i... | D019143 | T038 |
34,680,989 | cold shock protein south pole dwell soil bacterium arthrobact sp confer cold toler rice low temperatur critic environment factor restrict physiolog organ across kingdom prokaryot cold shock induc express various gene protein involv cellular process cold shock protein arcspa south pole dwell soil bacterium arthrobact sp... | D000222;D003080;D012988 | T040;T070;T067 |
34,680,988 | identif comprehens structur function analys exo gene famili cotton exo gene vital compon exocytosi complex particip biolog process rang plant cell divis polar growth mani exo gene plant function extens littl known exo gene famili cotton analyz four cotton sequenc databas identifi exo gene divid eight subgroup exoa exoh... | D017343 | T028 |
34,680,987 | develop new cancer treatment identifi focus genet mutat alter express gynecolog cancer advent next generat sequenc ngs cancer genom atlas tcga research network given gynecolog cancer molecular classif impact clinic practic new cancer treatment identifi target pathogen abnorm gene rapid develop promin progress gynecolog... | D009154 | T045 |
34,680,986 | identif character hsp gene famili reveal involv hsp grp trap heat stress respons chlami farreri heat shock protein hsps class ubiquit high conserv multi function molecular chaperon present live organ assist protein fold process form function protein present studi three hsp gene cfhsp cfgrp cftrap success identifi genom... | D018869 | T040;T039 |
34,680,985 | identif express profil circul microrna serum cysticercus pisiformi infect rabbit cysticercus pisiformi c pisiformi larval form taenia pisiformi parasit main liver omentum mesenteri rabbit caus huge econom loss rabbit breed industri microrna mirna short non code rna wide stabli distribut plasma serum numer data demonstr... | D020869 | T059;T063 |
34,680,983 | genom wide character spl gene famili codonopsi pilosula reveal function cpspl cpspl promot accumul secondari metabolit growth c pilosula hairi root squamosa promot bind protein like spl transcript factor play critic role regul divers aspect plant growth develop includ veget phase chang plant architectur anthocyanin acc... | D018745 | T028 |
34,680,982 | identif valid qtl bacteri leaf streak resist rice oryza sativa l thai xoc strain rice one import food crop world vital import mani countri various diseas caus fungi bacteria virus constant threaten rice plant caus yield loss bacteri leaf streak diseas bls caus xanthomona oryza pv oryzicola xoc one devast rice diseas ho... | D040641 | T028 |
34,680,981 | opportun challeng improv public research program plant breed enhanc underutil plant genet resourc tropic american tropic hotspot wild domest plant biodivers still underutil breed program despit conserv region gene bank improv program depend long term public fund mainten special staff unfortun financi up down complic st... | D017343;D000069600;D014329 | T040;T070;T028 |
34,680,980 | dna methyl pig fut promot alter mrna express regul e coli f suscept post wean diarrhea pwd frequent associ e coli f infect piglet howev under molecular mechan concern resist e coli f local wean piglet china clear understood present studi compar analysi transcriptom fucosyltransferas fut evalu key candid correl resist e... | D019175;D011401 | T044;T114;T123 |
34,680,978 | compound heterozygot point mutat chromosom microdelet involv otudb coincid zmiz variant syndrom intellectu disabl otudb zmiz gene recent identifi caus syndrom intellectu disabl id share phenotyp facial dysmorph distal limb anomali seizur disord otudb zmiz relat id inherit autosom recess autosom domin pattern respect re... | D020022 | T032 |
34,680,976 | evalu impact sex bias genet admixtur america analysi haplotyp data general imbal proport disembark male femal america document tran atlant slave trade coloni era although less promin recent imbal may left signatur genom modern day popul characteris high level admixtur analysi uniparent system evalu continent proport ra... | D005828;D063426 | T054;T090 |
34,680,974 | genet divers popul structur asian tiger mosquito aed albopictus vietnam evid genet differenti climat region aed albopictus nativ mosquito southeast asia high potenti diseas transmiss understand ae albopictus popul develop speci nativ rang use plan futur control strategi identifi sourc invas rang present studi aim inves... | D005828;D010802 | T062;T090;T078 |
34,680,972 | covid infect alter microbiom elit athlet sedentari patient similar bacteri flora regular exercis upgrad effici immun system benefici alter composit gastro intestin microbiom test hypothesi activ athlet divers microbiom sedentari subject could provid better protect covid infect twenti activ compet athlet ca male femal n... | D056352;D000069196;D057185 | T007;T079;T098;T097;T001;T033 |
34,680,971 | dbtrend web server trna express profil small rna sequenc data human transfer rna trna key compon translat machineri play critic role stress condit various diseas knowledg regard import trna function increas biolog role still well understood current comprehens databas web server provid express landscap trnas across vari... | D030541;D020407;D012984 | T090;T170;T073 |
34,680,967 | eukaryot genom show strong evolutionari conserv k mer composit correl contribut intron intergen region sever strong conserv dna sequenc pattern intron intergen region iir consist short tandem repeat strs repeat length bp alreadi describ kingdom animalia work expand search analysi conserv dna sequenc pattern wider rang ... | D019143 | T038 |
34,680,966 | angiotensin convert enzym ace gene polymorph phenotyp express covid symptom renin angiotensin aldosteron system raa appear play import role sar cov infect polymorph within gene control enzymat system candid elucid pathogenesi covid sinc covid pulmonari diseas also affect mani organ system throughout bodi multipl way st... | D000086382;D015967;D005838;D054643;D007703;D011110 | T116;T047;T045;T129;T032;T067;T126 |
34,680,962 | complet mitochondri genom one breed strain asian swamp eel monopterus albus zuiew use pacbio illumina sequenc technolog phylogenet analysi synbranchiform asian swamp eel monopterus albus zuiew commerci import fish due nutrit valu eastern southeastern asia one local strain albus distribut jianghan plain china subject se... | D010802 | T062;T078 |
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