PMID int64 27.8M 36.2M | Title/Abstract stringlengths 7 10.7k | MeshTerms stringlengths 7 104 | SemanticTypes stringlengths 4 84 |
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34,670,703 | earli evid econom effect covid hors show industri covid pandem affect econom status sector global economi includ hors show industri report impact covid person hors show earli assess impact economi object studi qualtric survey instrument dissemin hors show particip social media page email n major respond femal repres cross section unit state particip report plan attend averag sd person hors show unabl attend averag sd due covid restrict particip report spend mean sd per show hors show relat expens annual american hors council report hors compris competit sector hors owner show hors particip generat b expens annual reduc attend person show result decreas annual expenditur suggest econom loss billion quantifi direct effect use implan input output model estim total econom impact reduc attend result reduct billion reduct approxim job within hors show industri addit industri contribut gdp valu ad reduc billion earli assess econom impact associ reduct person hors show vital understand long term implic industri | D000086382;D006734 | T047;T067 |
34,670,702 | germ cell transplant stallion test product donor deriv sperm use spermatogoni stem cell transplant studi various anim includ mice rat goat boar dog sheep monkey howev germ cell transplant appli stallion object studi produc donor germ cell deriv sperm use germ cell transplant stallion donor germ cell transplant parenchyma recipi stallion treat busulfan iv inject mgkg bodi weight prepar donor singl germ cell tissu g testi subject enzym digest procedur donor testicular germ cell minimum essenti medium supplement fetal bovin serum transplant testi recipi stallion rate mlmin semen recipi stallion collect use artifici vagina week germ cell transplant general sperm evalu libido test perform microsatellit fingerprint marker perform identifi presenc donor deriv sperm semen recipi stallion sperm observ total progress motil exceed throughout experiment period libido recipi stallion unchang donor deriv sperm could detect semen recipi stallion genotyp conclus transplant donor germ cell testicular parenchyma stallion optim transplant techniqu produc donor deriv sperm | D017690;D013094;D013737 | T025;T023;T061 |
34,670,701 | clinic outcom transcerv infus combin procain penicillin gentamicin late term pregnant mare transcerv intrauterin infus antibiot may effect treat pathogen associ fetal neonat diseas pregnant mare standard system rout object studi assess safeti transcerv antibiot infus character gestat outcom nine healthi pregnant poni mare follow singl transcerv infus million iu procain penicillin mg gentamicin ml volum late gestat assess fetal placent health perform serial measur combin thick uterus placenta ctup fetal heart rate mare foal close monitor periparturi period fetal heart rate ctup remain unchang infus evid fluid accumul signific increas time point hour mare foal without complic day antibiot infus mean gestat age day two nine foal display sign mild neonat maladjust syndrom respond minim support care foal surviv wean without complic | D005839;D010402 | T195;T121;T109 |
34,670,700 | serolog molecular detect anaplasma spp blood healthi hors preliminari studi hors east texa anaplasmosi diseas caus bacterium anaplasma phagocytophilum spread infect tick hors phagocytophilum general caus transient infect character fever lethargi inappet ventral edema petechia icterus ataxia recumb muscl stiff sever case death follow natur infect hors retain antibodi approxim year detect immunofluoresc antibodi assay current infect determin pcr assay white blood cell dna studi whole blood collect appar healthi hors locat east texa n west texa n new york n new jersey n determin serum antibodi pcr test bacteri dna hors test posit dna presenc phagocytophilum test posit serum antibodi hors test posit phagocytophilum posit serum antibodi presenc negat twenti msp posit hors locat east texa resid new york serum antibodi new york new jersey hors test posit texa hors test posit studi provid evid larg number hors expos phagocytophilum bacterium present east texa texa hors owner report treatment anaplasmosi current infect hors demonstr sign ill time sampl collect research understand differ diseas sever amongst equin popul warrant | D041081;D016873;D006734 | T007;T047 |
34,670,699 | use negat pressur wound therapi treatment limb wound case seri hors traumat limb injuri common hors negat pressur wound therapi npwt proven promot wound heal human medicin also describ treatment wound hors retrospect studi clinic record n anim assess categori wound durat npwt applic frequenc reset npwt devic technic complic toler procedur record wound classifi boni n articular n tenosynovi n muscular n cutan n npwt use help first intent heal preoper n postop n applic second intent heal n delay primari closur n durat npwt applic rang day mean system stay place period rang day mean n case heal consid satisfactori discharg n hors discharg whilst ideal npwt continu anim n euthan surgeri due unrel pain procedur well toler except hors show sign discomfort first applic studi demonstr npwt long period applic use success manag various type limb wound | D006734;D009140;D054843 | T074;T047;T061 |
34,670,698 | influenc stretch exercis warm cool physic perform mangalarga marchador hors hors agribusi complex import activ brazilian agricultur sector mangalarga marchador mm numer breed hors brazil tempera gait characterist beat step gait allow constant growth breed perform vs equestrian activ train manag current adopt mm hors base empiric scientif support necessari improv well hors competit maintain physic integr athlet therefor studi aim verifi effect stretch warm andor cool perform marcha test mm geld age year averag weight kg use pre experiment stage physic condit hors last day experiment phase last day consist marcha test perform everi day experiment design latin squar hors submit follow exercis protocol min marcha test follow offici regul brazilian associ hors breeder mangalarga marchador abccmm b min warm marcha test c min cool marcha test min warm marcha min cool marcha test e min stretch marcha test f min stretch min warm min cool test hors evalu marcha test heart rate hr respiratori rate rectal temperatur glucos lactat creatin kinas aspart aminotransferas cortisol data submit way analysi varianc exercis protocol evalu moment mean compar tukey test p hr blood lactat result indic benefici effect warm stretch practic perform mangalarga marchador hors submit simul marcha test accord offici abccmm regul last minut | D010805;D063996 | T038;T056 |
34,670,697 | risk factor jockey fall japanes thoroughbr flat race jockey safeti paramount import welfar perspect public percept retrospect case control studi aim identifi risk factor associ jockey fall jf flat race japan race associ jra jf race start hors racecours review data extract databas maintain jra offici accid report issu race steward seventeen possibl risk factor evalu use multivari logist regress identifi signific associ jf total jf incid record incid rate fall per start ci risk factor signific associ jf odd increas hors sustain catastroph musculoskelet injuri cmi ci p increas odd also associ dirt track surfac ci p apprentic jockey ci p smaller track size ci p larger field ci p longer race distanc per ci p sinc cmi identifi major contribut factor jf measur minim cmi may lead improv jockey safeti increas odd associ apprentic jockey may indic import jockey educ train jockey safeti proper staf medic profession especi race dirt smaller track larger field longer distanc recommend | D000058 | T037 |
34,670,696 | diagnost treatment challeng diaphragmat hernia equid concis review literatur diaphragmat hernia dh repres acut abdomin crisi respiratori symptom may occur differ type diaphragmat hernia dhs like typic dh morgagni hernia hiatal hernia diaphragmat diverticulum record equid dhs various clinic present prognos earli diagnosi prompt surgic repair high recommend order diminish ischem chang thorac abdomin viscera thus improv overal prognosi equid dh last decad prognosi dh equid better previous believ due improv diagnost tool general anesthesia equid particular system compromis gastrointestin surgeri develop thoracoscop techniqu use stapl surgic repair nevertheless sever diagnost treatment challeng still present manag dh equid diagnost challeng includ inconsist clinic sign dh acut natur associ colic absenc high qualifi diagnost tool increas awar case good clinic observ avail diagnost tool recommend overcom challeng also anesthesia reduct larg herniat organ herniorrhaphi major challeng preoper stabil care monitor select access surgic approach good intraop well postop support high recommend overcom challeng surgic repair particular prosthet herniorrhaphi seem effect close diaphragmat defect prevent recurr present review describ differ type dhs equid diagnost treatment challeng overcom challeng | D006551;D065630 | T047;T019 |
34,670,695 | microbi variabl commerci equin probiot probiot defin live microorgan confer health benefit host administ adequ amount therefor presenc viabl microorgan essenti previous studi report inconsist compar content probiot market use anim label claim howev author knowledg variabl product differ lot yet evalu object observ studi evalu content inter lot variabl commerci equin probiot product use cultur depend independ techniqu eleven probiot market use hors evalu microbi content use cultur depend independ techniqu content compar microorgan list quantiti label probiot statist analys perform use kruskal walli test none probiot met label claim nine statist signific inter lot variabl sever product lack microorgan list label base cultur polymeras chain reaction pcr analys | D019936 | T007 |
34,670,694 | system intrafollicular androgen concentr cycl mare evid androgen regul folliculogenesi support hypothesi intrafollicular testosteron androstenedion dehydroepiandrosteron dhea could modifi along follicular growth object studi evalu chang relat relationship system intrafollicular dhea post deviat impend ovul follicl sixti ovari taken slaughter clinic healthi mare accord size follicl classifi differ categori small mm medium mm larg mm follicular fluid ff sampl extract singl follicl intrafollicular concentr dhea signific higher system one intrafollicular system concentr strong posit correl dhea negat predomin androgen ff posit dhea negat correl follicular diamet signific increas larg medium small follicl size dhea signific higher small medium larg follicl size increas intrafollicular androgen suggest presenc androgen environ base biotransform dhea later follicl progress oestradiol e product advanc follicular growth evid signific correl system intrafollicular androgen consider help understand deepli role steroid physiolog follicular develop mare ad new segment scientif literatur | D000728;D006080 | T039;T023;T121;T125 |
34,670,693 | dynam metabol respons clot time peripher indic central fatigu hors compet km endur race deep knowledg metabol respons athlet hors exercis paramount import develop optim train program attain equilibrium good perform anim welfar studi investig dynam chang metabol clot time peripher indic central fatigu hors compet offici km endur race hors blood sampl collect rest pre within minut end race pe minut end race pe pe investig valu blood lactat glucos platelet plts serum leucin isoleucin valin tryptophan ratio tryptophan branch chain amino acid bcaa level trybcaa total protein non esterifi fatti acid plasma thrombin time tt prothrombin time pt activ partial thromboplastin time fibrinogen fb lactat plts non esterifi fatti acid bcaa trybcaa show higher valu pe pe pe pre p glucos show lower valu pe pe pe pre p higher tt valu found pe pe pe pre pe pe pe p fb higher pe pre pe pe p survey confirm hors perform prolong physic exercis experienc glycolysi lipid mobil amino acid metabol provid substrat fuel muscl contract | D000597;D010805 | T116;T038;T123 |
34,670,692 | copper toxic hors exist copper toxic thought rare condit hors howev number case diagnos brazil grow articl aim describ case copper toxic involv hors differ geograph locat discuss find physic examin differenti diagnos potenti caus five case refer differ properti least hors affect describ hemolyt anemia hemoglobinuria presenc heinz bodi elev aspart aminotransferas gamaglutamil transferas level detect case diagnosi base clinic histori sign laboratori test result copper level determin feed andor soil histopatholog find two hors progress acut death remain hors respond clinic manag without blood transfus depend diseas sever howev one hors sever return veterinari hospit euthan due complic one hors treat ammonium tetrathiomolybd two hors sever recur episod cours sever month uncommon present rumin suffer copper toxic excess copper associ soil fertil poultri litter treatment previous neighbor crop copper contain product conclud copper toxic occur hors may aris sever sourc andor associ predispos dietari factor given grow number case condit includ differenti diagnosi list proper prevent dietari pastur fertil measur adopt | D000743;D006734 | T047 |
34,670,691 | evalu optic refractomet assess failur transfer passiv immun foal aim present studi evalu correl total protein measur optic refractomet concentr igg radial immunodiffus rid determin perform optic refractomet diagnos failur passiv transfer immun fpti hour old foal blood collect foal n hour birth studi carri measur serum igg concentr rid test measur total protein tp optic refractomet correl coeffici measur tp concentr igg rid correl made igg idr level colostrum mare igg idr concentr plasma foal roc curv made identifi ideal cutoff point addit test sensit specif area curv auc calcul igg concentr rid posit correl refractomet colostrum igg concentr rid moder correl foal plasma igg rid concentr roc curv auc cutoff point found gdl optim combin sensit specif thus conclud total protein concentr refractomet show effect util evalu fpti foal sinc high sensit associ low cost easi handl easili carri field | D003126;D007074 | T129;T031;T121;T116 |
34,670,690 | primari uterin hemangiosarcoma thoroughbr case report year old maiden thoroughbr filli without previous histori mate reproduct manag refer clinic inspect due presenc sanguin vagin discharg sever abdomin pain transrect palpat indic uterin asymmetri transrect ultrasonographi reveal mass near cervix measur cm diamet heterogen echogen trabecul center well defin hyperecho border smaller mass surround larger uterin mass examin mare expel uterin mass vulva histolog immunohistochem cd factor viii examin expel mass suggest diagnosi hemangiosarcoma therefor therapeut hysterectomi perform examin uterin tissu confirm diagnosi howev mare euthan week later due postop complic anim subject necropsi intestin adhes surgic incis diagnos postop complic neoplasm found necropsi establish primari origin tumor case studi present first known report uterin hemangiosarcoma equin speci | D006394;D006734;D014594 | T191;T047 |
34,670,689 | total carbon dioxid adult standardbr thoroughbr hors tco total carbon dioxid test perform blood racehors mean combat practic administ alkal agent purpos enhanc perform purpos review present overview factor contribut tco review literatur regard tco adult standardbr thoroughbr hors demonstr rang variabl tco hors research publish topic tco bicarbon measur racehors access review pubm googl scholar primari search engin use sourc relev literatur main physicochem factor contribut chang tco hors rest chang strong ion concentr follow chang weak acid ie plasma albumin concentr wide normal distribut tco hors rang mmoll mmoll independ administr alkal agent blood tco affect main feed time day diurnal variat season exercis studi report hour hour chang tco racehors popul studi suffer lack valid regard whether hors administ alkal agent conclud normal rang tco non alkal standardbr thoroughbr hors signific wider appreci period elev tco appear normal mani hors rest tco test alon definit purpos determin alkal agent administ hors | D002245;D010805 | T038;T197;T123 |
34,670,688 | factor associ develop preval abnorm behavior hors systemat review meta analysi research believ develop preval abnorm behavior hors may caus sever environment biolog factor literatur offer numer report discuss caus effect stereotypi anim light studi aim conduct systemat review meta analysi scientif literatur summar main risk factor associ develop abnorm behavior hors search conduct cours four year portugues spanish english public review full text research thesi articl address issu within follow criteria present epidemiolog inform studi popul preval abnorm behavior equin popul factor associ develop preval stereotypi data extract studi insert excel spreadsheet analyz descript statist addit mann whitney u test use verifi exist signific differ methodolog direct observationquestionnair dataset also analyz data mine identifi main factor influenc preval abnorm behavior studi popul result show great variat mean preval abnorm behavior signific differ research conduct questionnair direct observ data mine techniqu identifi incorrect nutrit manag may main factor influenc develop preval abnorm behavior hors | D000066553;D013239 | T033;T048;T055 |
34,670,687 | uterin involut mare supplement dietari alga deriv omega fatti acid peripartum period differ approach use improv concept rate foal heat omega fatti acid famili deriv improv reproduct effici rumin literatur lack studi evalu compon equin object studi evalu effect mare dietari supplement microalga rich docosahexaeno acid dha peripartum follicular dynam uterin involut earli post partum eighteen pregnant mare particular breed kg bodi weight bw yr old use mare random assign control cont supplement microalga rich dha gkg bw alg treatment suppli prior expect foal date first ovul reproduct evalu perform earli post partum first ovul rectal palpat ultrasonographi follow paramet uterin endometrium diamet intrauterin fluid iuf uterin echogen uterus tone follicular dynam endometri cell sampl collect assess mrna express crp il akrc use rt qpcr data analyz mix procedur sas alg mare smaller uterin horn diamet greater uterin echogen post partum comparison cont treatment effect detect characterist evalu day effect observ uterin endometrium diamet iuf uterin echogen transcript abund endometri akrc supplement dha peripartum may benefit uterin involut process odd earli concept studi perform regard fertil | D019587;D058725 | T101;T079;T168;T061 |
34,670,685 | interpret forti three year trend expenditur public health canada long run trend tempor period data differ covid pandem rais concern around public health ph invest among oecd countri canada devot one largest share total health expenditur ph examin retrospect ph spend growth long period may hold lesson reach high share differ histor period use understand macroeconom condit affect ph spend growth use forti three year data examin real ph spend growth per capita compar thirteen canadian jurisdict key public fund healthcar sector physician hospit pharmaceut well four period defin macroeconom condit find five fold increas averag ph spend sinc growth physician hospit pharmaceut howev substanti variat ph growth period across countri concern rais ph spend data oecd countri explor differ spend estim report nation agenc ten provinci budgetari estim find former larger magnitud differ vari jurisdict much time although differ challeng presenc growth ph spend show growth may hospit better categor ph financ data warrant | D000086382;D005102 | T081;T047;T067 |
34,670,684 | develop confid oral maxillofaci dental core traine nation review traine experi studi consid confid dental core traine dcts matur progress first six month oral maxillofaci surgeri omf train post traine differ incent embark year omf develop addit skill settl general dental practic step toward specialti train help decid career direct tradit omf year associ creat well round confid clinician survey dcts three stage six month period monitor confid clinic domain assess dentofaci infect mandibular fractur midfac fractur intraoralextraor swell airway risk intraoralextraor lesion benignmalign ctmri scan perform intraoralextraor sutur studi demonstr increas traine confid across domain first six month omf post particular signific increas assess dentofaci infect mandibularmidfac fractur intraor extraor lesion swell | D013515 | T091 |
34,670,683 | network support negat life event associ chronic cardiometabol diseas outcom stress negat life event may import risk factor chronic cardiometabol condit increas preval among young adult support person network known buffer stress negat life event yet evid relationship among young older adult remain unclear | D003920;D006973 | T047 |
34,670,681 | risk factor communiti onset pneumonia caus drug resist pathogen prospect cohort studi consensu definit risk factor drug resist pathogen drp communiti onset pneumonia cop healthcar associ pneumonia criteria abandon found weak discrimin power aim identifi risk factor drp cop | D017714;D003428;D055624;D011014 | T007;T047;T050 |
34,670,680 | impact nutrit lifestyl modif health main recommend public health entiti includ healthi diet physic activ main lifestyl factor impact develop chronic diseas cardiovascular metabol diseas cancer even neurolog diseas random clinic trial design demonstr lifestyl modif chang pattern chronic diseas develop progress among nutrit one impact factor therefor nutrit diet also includ differ random clinic trial show favor impact nutrit modif particip health nevertheless studi design consider differ futur studi need support nutrit modif choic healthi consid diet like mediterranean diet shown impact chronic diseas cardiovascular risk adult life expect main due anti inflammatori antioxid properti furthermor high intak fiber fruit veget togeth low intak fat energi dens process food contribut inflamm reduct robust immun system lead besid well known properti lifestyl modif must person accord avail food geograph local healthi status patient | D002318;D038441 | T047;T061 |
34,670,678 | day discharg follow nuss repair comparison intercost nerv cryoablat inc signific improv pain control follow nuss repair pectus excavatum pe studi sought evalu patient undergo nuss repair inc compar nuss repair era protocol inc intercost nerv block inb | D000765;D005660 | T019;T061 |
34,670,677 | pediatr surgeri clinic lgbtq inclus creat inclus lgbtq environ import provis inclus care cross section studi assess whether patient intak form pediatr surgeri depart lgbtq inclus l | D000072339 | T098 |
34,670,676 | posterior tibial tendon disloc case report isol posterior tibial tendon disloc rare condit diagnosi challeng especi acut clinic set predispos factor includ shallow posterior tibial tendon groov tear flexor retinaculum report case traumat sublux posterior tibial tendon illustr imag find surgic techniqu posterior tibial tendon disloc detect use dynam ultrasound magnet reson essenti comprehens evalu includ under predispos anatom abnorm associ patholog condit conserv treatment often unsuccess thus surgic approach need ampliscop guidanc bone tunnel creat behind retromalleolar groov posterior tibial tendon locat new groov retinaculum attach tighten anchor absorb sutur anterior margin sulcus month follow patient complain residu pain abl perform normal daili activ without limit tendon disloc | D016512;D004204;D013708 | T037 |
34,670,674 | enhanc chondrogenesi chondrocyt co cultur mesenchym stromal cell implic cartilag repair cellular therapi base chondrocyt implant wide use procedur induc cartilag regener howev dedifferenti process cell suffer limit capac prolifer cultur vitro restrict use cellular therapi protocol investig capac mesenchym stromal cell mscs promot chondrogenesi chondrocyt chondron cocultur system murin chondrocyt chondron cocultur mscs differ cell ratio two dimension three dimension cultur system high prolifer cell chondrocyt morpholog enhanc gag product express cartilag gene aggrecan type ii collagen sox observ chondrocytesmsc cocultur contrast fibroblastoid cell regul cartilag gene express reduct gag product observ chondronsmsc cocultur chondrocyt within cartilag lacuna surround extracellular matrix observ chondrocytesmsc pellet mscs promot prolifer function chondrocyt cultur system transplant chondrogen construct base mscs chondrocyt may constitut potenti treatment induc cartilag repair | D020219;D059630 | T025;T042 |
34,670,672 | research progress function tissu resid regulatori cell trtreg regulatori cell treg specif express forkhead box p foxp cd indispens compon immun system maintain immun self toler homeostasi recent year treg exist non lymphat tissu gradual obtain peopl attent genom proteom metabol regul vivo vitro function studi found tissu resid treg uniqu phenotyp differ circul treg perform non immun function addit immunosuppress function tissu summar various function non lymphoid tissu treg aim provid refer studi function mechan tissu resid treg treatment target tissu resid treg | D051858;D050378 | T025;T116;T123 |
34,670,671 | prepar identif mous anti helicoverpa armigera sulfatas hasulf polyclon antibodi object obtain prokaryot express helicoverpa armigera sulfatas hasulf protein prepar polyclon antibodi method prokaryot express vector first construct induc protein express crude recombin protein collect purifi nickel column inject immun mice mous blood collect detect titer polyclon antibodi elisa immun specif detect western blot result recombin plasmid obtain fusion protein posit express purifi elisa data show polyclon antibodi titer western blot show prepar antibodi could bind recombin protein express vitro natur sulfatas cotton bollworm conclus prokaryot express recombin hasulf protein obtain specif mous polyclon antibodi prepar | D000906;D009036 | T204;T129;T121;T116 |
34,670,670 | bioinformat analysi differenti express microrna children bronchial asthma object studi import micro rnas mirna target gene children asthma method microarray data pediatr asthma gse download geo databas differenti express mirna dem analyz r program languag potenti target gene dem predict mirdb mirtarbas targetscan tool annot r softwar packag clusterprofil protein protein interact ppi mirna hub gene network construct string databas cytoscap softwar final associ hub gene asthma verifi ctd databas result total mirna signific differenti express includ regul regul target gene predict go analysi show target gene main involv epitheli cell prolifer intercellular junction biolog process cellular compon main relat plasma membran membran compon molecular function includ gtpase activ receptor bind kegg pathway show target gene main involv pik akt signal pathway foxo signal pathway accord network analysi mir p mir p import regul molecul mir mir b p mir p mir p mir signific regul mirna associ childhood asthma potenti target gene ccnd sirt hdac key gene select conclus studi identifi seven dem target gene potenti role occurr develop childhood asthma | D001249;D035683 | T047;T114;T123 |
34,670,669 | curcumin combin fu promot autophagi regul express yes associ protein yap hepatocellular carcinoma cell object investig effect curcumin combin fu autophagi yes associ protein yap express hepatocellular carcinoma cell method hepg cell hepg cell stabl yap overexpress hepg cell stabl yap knockdown treat moll curcumin gml fu alon combin hour prolifer cell detect mtt assay express chang autophagi marker microtubul associ protein lcii yap detect western blot result two agent use combin inhibit rate tumor cell prolifer signific higher singl agent group compar control group group curcumin group fu combin group could increas express level lcii protein decreas yap hepg cell hepg cell stabl yap overexpress hepg cell stabl yap knockdown conclus combin curcumin fu induc autophagi regul express yap hepatocellular carcinoma cell | D006528;D003474;D008113 | T130;T191;T121;T109 |
34,670,668 | c ski improv beagl atrial structur remodel suppress tgf smad signal p mapk pathway object investig role mechan c ski atrial structur remodel rapid atrial pace canin model method express level c ski smooth muscl actin sma type iii collagen col atrial tissu patient atrial fibril af correl detect real time quantit pcr pearson correl analysi canin atrial rapid pace model construct express distribut sma col detect immunohistochem stain level inflammatori cytokin interleukin il toll like receptor tlr serum atrial tissu determin elisa regul effect c ski sma col transform growth factor tgf smad pathway p mapk pathway overexpress detect western blot result c ski express regul atrial tissu af patient show negat correl express sma col af addit c ski express show regul canin atrial rapid pace model overexpress c ski signific inhibit sma col level well level inflammatori cytokin il tlr serum atrial tissu allevi af induc atrial fibrosi inhibit tgf smad pathway p mapk pathway canin atrial rapid pace model conclus overexpress c ski improv atrial structur remodel induc rapid pace inhibit tgf smad pathway p mapk pathway | D053773;D048051 | T116;T121;T126;T123 |
34,670,667 | overexpress cd inhibit apoptosi sw human colon cancer cell block fasfasl pathway object studi effect overexpress cd apoptosi human colon cancer sw cell under mechan method express cd thirti four tumor analyz along correl immun cell infiltr apoptosi adhes angiogenesi colon cancer refer tcga databas meanwhil packag lentivirus vector express cd success transfect sw cell vector stabli express cd cell divid blank control group empti bodi virus infect group cd overexpress group use follow assay infect effici detect fluoresc microscop western blot analysi apoptosi rate detect flow cytometri express fasl caspas caspas detect western blot analysi result tcga databas analysi show cd overexpress varieti tumor includ colon cancer mrna level cd relat infiltr cd cell cd cell b cell macrophag neutrophil colon cancer microenviron express cd involv biolog process apoptosi adhes angiogenesi furthermor protein protein interact network suggest cd interact protein relat death receptor pathway apoptosi rate sw cell express fasl caspas caspas protein overexpress cd group signific higher blank control group empti vector virus infect group conclus cd high express associ immun cell infiltr colon cancer overexpress cd may inhibit apoptosi block fasfasl pathway human colon cancer sw cell | D051928;D003110 | T129;T191;T116 |
34,670,666 | torment acid inhibit prolifer promot apoptosi lx human hepat stellat cell via block nf b signal pathway object investig regul function torment acid ta nf b signal pathway analyz effect prolifer apoptosi lx human hepat stellat cell mechan method cultur lx cell random normal control group platelet deriv growth factor bb pdgf bb stimul group ngml pdtc group ngml pdgf bb combin mmoll pdtc ta treat group ngml pdgf bb combin moll ta effect ta cell prolifer detect mtt assay activ asl alt tbil detect use commerci avail kit cell apoptosi determin flow cytometri mrna nf b p detect real time quantit pcr protein express nf b p phosphoryl nf b p p nf b p ib sma tgf bcl bax detect western blot result compar pdgf bb ta signific inhibit activ prolifer lx cell decreas protein express sma tgf ta treatment reduc level asl alt tbil cell cellular damag ta signific induc lx cell apoptosi regul express anti apoptot protein bcl regul express pro apoptot protein bax addit ta mark inhibit express nf b p mrna protein phosphoryl nf b p ib protein conclus ta inhibit prolifer promot apoptosi lx cell block nf b signal pathway | D055166;D016328 | T025;T129;T116 |
34,670,665 | cisplatin promot pd l express human lung adenocarcinoma cell via activ erk pathway object investig effect cisplatin ddp express program death ligand pd l human lung adenocarcinoma cell possibl mechan method human lung adenocarcinoma cell cultur vitro treat mgl ddp hour cck assay use detect cell prolifer inhibit rate half maxim inhibitori concentr ic calcul optim inhibit time hour ic select subsequ experi cell random four group blank control group group ddp ic group moll mitogen activ protein kinas kinas inhibitor pd group ddp ic combin moll pd cell cultur hour express erk p erk detect western blot pd l express detect flow cytometri result compar control group express pd l cell treat ddp regul dose depend manner optim time hour ic mgl also compar control group express p erk pd l ddp treatment group increas express p erk group pd decreas express p erk pd l group ddp combin pd lower group ddp higher group pd conclus ddp regul express pd l cell activ erk signal pathway | D000077192;D000970;D008175 | T191;T121;T109 |
34,670,664 | mir b p inhibit prolifer autophagi acut myeloid leukemia cell target atg object investig effect mir b p prolifer autophagi acut myeloid leukemia aml cell molecular mechan method base geo tcga databas express mir b p aml cell associ clinic prognosi patient analyz bioinformat softwar express mir b p aml cell detect real time quantit pcr mir b p mimic mir b p inhibitor transient transfect aml cell line thp nb liposom mediat transfect respect prolifer leukemia cell evalu cck assay ethynyl deoxyuridin edu label protein level bcl bcl associ x protein bax autophagi marker lc p autophagi relat gene atg detect western blot target bind mir b p atg measur dual luciferas report gene assay effect mir b patg axi phenotyp aml cell observ rescu experi result decreas express mir b p found leukemia blast aml patient overal surviv rate aml patient low express mir b p signific lower control group overexpress mir b p inhibit thp cell prolifer promot apoptosi downregul lcii atg protein level upregul p protein level inhibit express mir b p nb cell opposit effect mir b p signific reduc luciferas activ wild type atg express vector result rescu experi show overexpress atg revers inhibitori effect mir b p upregul cell prolifer autophagi inhibit atg express weaken promot effect mir b p downregul cell phenotyp conclus mir b p inhibit vitro prolifer autophagi aml cell target atg | D015470 | T191 |
34,670,663 | il il il il effect promot generat human cd central memori cell vitro object compar effect differ cytokin combin combin anti cdcd bead vitro induc generat central memori cell tcm method peripher blood mononuclear cell pbmcs isol healthi donor naiv cd cell purifi use immunomagnet bead stimul cdcd antibodi hour cell treat differ cytokin combin follow interleukin il il il il il il il il il il automat blood cell count instrument use cell count carboxyfluorescein diacet succinimidyl ester cfse employ test cell prolifer flow cytometri adopt measur immun memori phenotyp apoptosi intracellular factor express cd cell induc differ cytokin combin express bcl determin western blot analysi result unlik cytokin combin il il il il promot prolifer cd cell signific increas express cd cdl cdra central memori cell subset time il il il il treatment signific reduc secret level ifn perforin granzym b level cell apoptosi also signific decreas conclus cytokin combin il il il il effect induc differenti naiv cd cell cd tcm cell vitro provid new strategi generat human cd tcm immunotherapi | D007156;D015851 | T129;T042;T121;T116 |
34,670,662 | lncrna h particip progress synovi inflamm collagen induc arthriti cia mice promot activ fibroblast like synovi cell object investig effect lncrna h fibroblast like synovi cell fls collagen induc arthriti cia mice method fls isol cultur patient rheumatoid arthriti ra adenovirus lentivirus sirna use regul regul express h ra fls brdu transwel tm assay cell scratch assay employ evalu prolifer invas migrat ra fls respect mice cia local inject lv sh h progress cia observ paw thick clinic arthrit index histolog analysi result express h close associ prolifer invas migrat fls cell knockdown h signific amelior progress cia mice conclus h involv synovi inflamm progress cia mice promot activ fls | D001169 | T050 |
34,670,661 | ehrlichiosi anaplasmosi among transfus transplant recipi unit state ehrlichiosi anaplasmosi emerg tickborn diseas also transmit blood transfus organ transplant sinc ehrlichiosi anaplasmosi case unit state increas substanti result potenti risk transplant transfus recipi review ehrlichiosi anaplasmosi case among blood transfus solid organ transplant recipi unit state peer review literatur center diseas control prevent investig identifi case transfus associ case case transplant recipi case donor deriv case ill occur year transplant diseas remain case occur year transplant suggest donor deriv diseas unlik sever ill death report among transfus transplant recipi clinician alert possibl infect among transfus transplant recipi prevent sever complic death quick treat | D000712;D016873;D016377 | T047;T061 |
34,670,660 | fatal co infect sar cov legionella pneumophila england legionella pneumophila sever acut respiratori syndrom coronavirus sar cov caus pneumonia l pneumophila acquir water sourc sometim healthcar set report fatal case l pneumophila sar cov co infect england clinician awar possibl l pneumophila infect among sar cov patient | D000086382;D060085;D016952;D007877 | T007;T047;T067 |
34,670,659 | hepat virus incid rate biomark dynam plasma donor unit state unit state current affect widespread hepat virus hav outbreak investig hav incid rate among sourc plasma donor unit state sinc serial donat hav posit frequent donor analyz common biolog marker obtain detail pictur cours infect found consider increas incid rate shift outbreak hotspot time although individu biomark profil high variabl hav rna typic high peak biphas decreas often remain detect sever month one donor biomark pattern indic previous exposur find show current hav outbreak spill plasma donor popul detail result present improv comprehens hav infect relat public health aspect addit captur full rna curv enabl estim hav doubl time | D006506;D030041 | T047;T005 |
34,670,658 | invas malaria vector anophel stephensi mosquito sudan anophel stephensi mosquito urban malaria vector asia recent invad horn africa detect emerg stephensi mosquito noncontigu state eastern sudan result mitochondri dna sequenc suggest possibl distinct invas potenti neighbor countri | D000852;D008288 | T204;T047 |
34,670,657 | emerg vibrio cholera sequenc type south africa describ molecular epidemiolog cholera south africa vibrio cholera sequenc type st recent emerg becam preval v cholera biotyp el tor pandem clone st isol found across larg spatial tempor distanc suggest local st spread | D002771;D041241 | T007;T047 |
34,670,656 | high pathogen avian influenza hn virus wild red fox netherland detect infect high pathogen avian influenza hn virus clade b red fox vulp vulp cub found wild neurolog sign netherland virus relat avian influenza virus found wild bird area | D053124;D009980;D005585 | T047;T005 |
34,670,655 | toward cholera elimin haiti studi describ appar discontinu cholera transmiss haiti sinc februari vulner persist vaccin remain limit find suggest case area target intervent conduct rapid respons team play key role question presenc environment reservoir haiti discuss progress toward elimin | D002771 | T047 |
34,670,654 | acut chaga diseas manifest orbit cellul texa usa report case acut vectorborn chaga diseas acquir local central texa usa manifest romaa sign initi mistaken orbit cellul infect fail respond antibiot dna base next generat sequenc plasma yield high level trypanasoma cruzi result confirm pcr | D014355;D054517;D014349 | T204;T047 |
34,670,653 | isol novel mycobacterium speci skin infect immunocompromis person investig case cutan infect immunocompromis patient china caus novel speci within mycobacterium gordona complex result whole genom sequenc indic strain consid gordona complex actual polyphylet design close relat speci | D009161;D009165 | T007;T047 |
34,670,652 | epidemiolog analysi effort achiev sustain malaria elimin along china myanmar border malaria case dramat declin china along myanmar border attribut main adopt surveil respons approach indigen case report china sinc counti middl southern part border area higher risk malaria import reestablish elimin | D008288 | T047 |
34,670,651 | associ share live space covid univers student wisconsin usa describ characterist associ coronavirus diseas covid among student resid univers campus student receiv covid diagnosi fall semest student share bedroom suit approxim twice odd contract covid live alon | D000086382;D014495 | T092;T047;T073;T067 |
34,670,650 | genet diverg high pathogen avian influenza hn virus wild bird eastern china late detect high pathogen avian influenza hn virus migratori duck shanghai china phylogenet analysi repres isol identifi sublineag clade b sublineag form separ cluster isol east asia europ | D000071225;D005585 | T047;T005 |
34,670,649 | co infect speci mycobacteria identifi use next generat sequenc identifi co infect speci mycobacteria woman new york new york usa use next generat sequenc procedur use identifi co infect multipl mycobacteria trace geograph origin strain investig transmiss dynam suscept popul gain insight prevent control | D060085;D009161;D009165 | T007;T047 |
34,670,648 | popul genom infer mycobacterium avium complex cluster cystic fibrosi care center unit state mycobacterium avium complex mac speci constitut mycobacteria infect person cystic fibrosi cf unit state littl known genom divers transmiss perform whole genom sequenc mac isol person cf cystic fibrosi care center cfccs across state compar isol genom identifi instanc share strain person cf among person multipl isol sequenc mac strain type genom comparison reveal cluster high similar isol cluster patient share cfccs includ person cf provid genom evid high similar mac strain share among patient cfccs polyclon infect high genet similar mac isol consist multipl mode acquisit person cf acquir mac infect | D003550;D015270 | T047 |
34,670,647 | enceph death wild mammal rehabilit center infect high pathogen avian influenza hn virus unit kingdom report diseas mortal event involv swan seal fox wildlif rehabilit center unit kingdom late five swan onset high pathogen avian influenza virus infect captiv subsequ seal fox die euthan onset clinic diseas avian origin influenza virus subtyp hn retrospect determin caus diseas infect seal manifest seizur immunohistochem molecular test postmortem sampl detect neurolog distribut viral product fox die overnight sudden onset inappet postmortem tissu reveal neurolog respiratori distribut viral product live virus isol swan seal fox singl genet chang detect potenti adapt mutat mammalian deriv viral sequenc human influenza like ill report week event | D004660;D000071225;D005585;D046048 | T015;T047;T005 |
34,670,646 | trace origin spread molecular evolut zika virus puerto rico reconstruct zika virus epidem puerto rico use complet genom uncov epidem origin spread evolutionari dynam studi reveal epidem propel multipl introduct spread across island intric evolutionari pattern month cryptic transmiss | D058872;D000071244;D000071243 | T047;T005;T067 |
34,670,645 | multidrug resist methicillin resist staphylococcus aureus associ bacteremia monocyt evas rio de janeiro brazil type methicillin resist staphylococcus aureus mrsa isol collect hospit rio de janeiro brazil metropolitan area found multipl new clonal complex cc sequenc type replac previous domin mrsa lineag hospit whole genom analysi isol reveal emerg sublineag multidrug resist mrsa sequenc type staphylococc cassett chromosom mec ii spa design rio de janeiro rdj clone use molecular clock analysi hypothes lineag began expand rio de janeiro metropolitan area multivari analysi support associ bloodstream infect cc lineag includ rdj clone compar close relat isol repres isol rdj clone effect evad immun function relat monocyt cell evidenc decreas phagocytosi rate increas number viabl unphagocytos free bacteria vitro exposur monocyt | D016470;D055624;D013203 | T007;T047 |
34,670,644 | genom profil mycobacterium tuberculosi strain myanmar multidrug resist major threat global elimin tuberculosi tb perform phenotyp drug suscept test whole genom sequenc isol consecut patient given diagnosi tb yangon myanmar juli june identifi isol use genexpert platform evalu drug resist profil total isol rifampin resist rifampin resist isol genom relat indic repeat emerg resist popul rather extens local transmiss detect resist mutat new oral drug includ bedaquilin pretomanid current genexpert mtbrif system need modifi use newli launch xpert mtbxdr cartridg line probe assay introduc new oral drug replac current use treatment regimen multidrug resist tb also use treat tb myanmar | D009169;D018088 | T007;T047 |
34,670,643 | chang pattern diseas sever blastomyc dermatitidi infect quebec canada retrospect multicent cohort studi assess tempor chang sever mortal rate blastomycosi quebec canada identifi risk factor death patient blastomycosi primari outcom day caus death among patient need hospit die note increas proport sever case age diagnosi proport diabet immunocompromis patient time independ risk factor death age adjust odd ratio aor ci immunosuppress aor ci involv lung lobe aor ci associ blastomyc genotyp group caus mortal proport sever case blastomycosi increas quebec past year partial explain higher number immunosuppress patient | D001758;D001759 | T004;T047 |
34,670,641 | past experi surpris medic bill drive issu knowledg concern attitud toward feder polici intervent scholar journalist devot consider attent understand circumst american receiv surpris medic bill previous research issu focus scope problem includ condit like lead surpris bill howev exist literatur almost exclus reli claim data limit understand consum experi attitud toward polici chang address surpris bill use survey administ nation repres sampl american analyz consum experi surpris bill knowledg issu concern american receiv surpris bill past experi influenc polici prefer toward feder action surpris bill analysi demonstr knowledg concern surpris bill highest among educ previous receiv surpris bill factor also predict support feder polici action high level support feder polici action across popul includ among liber conserv howev detail feder polici propos receiv signific less support among american suggest stand alon polici action may viabl result show bipartisan support among american consum feder action surpris bill abstract consist view specif polici propos | D001290;D057766 | T170;T078;T041;T055 |
34,670,640 | inequ preval major depress disord brazilian slum popul cross section analysi mental health slum resid research global depress signific sourc worldwid morbid brazil larg slum dwell popul often consid part general urban poor demograph studi aim identifi preval distribut depress brazil compar mental health inequ slum non slum popul | D003865;D011204 | T080;T048 |
34,670,622 | vertebr arteri dissect term pregnanc cervic spine manipul case report review literatur vertebr arteri dissect uncommon potenti fatal vascular event case aim describ pathogenesi clinic present vertebr arteri dissect term pregnant patient moreov focus differenti diagnosi review avail evid | D020217 | T047;T037 |
34,670,620 | role sex gender women eye health dispar unit state unit state women higher risk develop vision impair serious eye diseas age relat macular degener thyroid eye diseas chronic dri eye diseas men dispar eye diseas due biolog widen even consid factor social determin health gap research data literatur polici insuffici provid patient educ limit screen treatment option sex gender dispar eye health clinic address burdensom patient qualiti life health care econom system result press popul health issu negat impact women | D011788;D016387 | T091;T078 |
34,670,619 | gut microbiota microglia brain interact alzheim diseas knowledg base multi dimension character interact gut microbiota microglia age may modul alzheim diseas ad pathogenesi precis natur interact known | D000544;D000069196 | T048;T047;T007;T001 |
34,670,613 | h nmr base metabol profil identifi non invas diagnost predict urinari fingerprint q spinal muscular atrophi q spinal muscular atrophi sma disabl life limit neuromuscular diseas recent year novel therapi shown improv clinic outcom yet absenc reliabl biomark render clinic assess prognosi possibl alreadi affect newborn posit newborn screen result sma imprecis difficult therapeut decis stratif individu therapi remain challeng especi symptomat children aim proof concept feasibl studi explor valu h nuclear magnet reson nmr base metabol profil identifi non invas diagnost prognost urinari fingerprint children adolesc sma | D009134;D020388 | T047 |
34,670,612 | obstetr gynecolog specialist need call ophthalmologist urgent case report report case healthi year old femal patient assess gynecolog emerg depart genit ulcer fever blur vision suspicion herp simplex virus lesion diagnosi behet diseas made report case aim includ behet diseas differenti diagnosi genit ulcer emphas emerg vision loss irrevers | D001528;D006176;D009774;D000072163 | T091;T047;T097 |
34,670,611 | pneumonectomi child due belat diagnosi foreign bodi aspir case report earli diagnosi fiberopt rigid bronchoscopi method gold standard manag tracheobronchi foreign bodi otherwis nonrecogn bronchial foreign bodi caus irrevers damag airway lung defici health system note mani develop countri madagascar combin fundament problem relat children condit determin social educ factor make almost imposs provid earli appropri manag penetr syndrom | D005547;D011013 | T061;T072;T037;T020 |
34,670,610 | size shape plate size wine glass bottl impact self serv food alcohol physic properti tablewar could influenc select consumpt food alcohol consider uncertainti howev around potenti effect differ size shape tablewar much food alcohol peopl self serv studi aim estim impact plate size shape amount food self serv wine glass bottl size amount wine self pour | D014920 | T168 |
34,670,609 | multicent studi qualiti life greater patient congenit ichthyos autosom recess congenit ichthyos arci genet heterogen group rare chronic disord character general skin scale hyperkeratosi erythroderma palmoplantar keratoderma addit featur includ ectropion eclabium ear deform foul smell joint contractur walk problem recurr infect well pruritus pain curat therapi avail diseas care main reli daili applic topic emolli keratolyt whole bodi surfac altogeth diseas sign symptom treatment modal major impact qualiti life patient caregiv howev studi evalu famili diseas burden arci | D016113;D017490;D007645 | T047;T019 |
34,670,607 | revis recommend cso hns taskforc perform tracheotomi covid pandem differ year make earli part covid pandem canadian societi otolaryngolog head neck surgeri cso hns task forc publish recommend perform tracheotomi sinc understand virus evolv ongo intens research effort new literatur help us better understand various aspect includ patient outcom health care worker hcw risk associ tracheotomi covid pandem accord task forc evalu revis previous recommend | D017053;D010036;D014140 | T058;T091;T061 |
34,670,605 | perceiv social built environ associ leisur time physic activ among adult sri lanka although perceiv neighbourhood environ consid predictor leisur time physic activ ltpa evid limit south asia thus aim determin associ neighbourhood social built environ featur carri ltpa among adult colombo district sri lanka cross section studi among adult carri use valid questionnair physic activ pa built environ data collect multipl logist regress analysi conduct assess associ environ characterist ltpa adjust gender age employ status incom level sector resid | D000076624;D007899 | T056;T078 |
34,670,603 | impact bmi waist circumfer epigenom wide dna methyl identif epigenet biomark blood ewa multi ethnic asian individu preval obes relat chronic diseas increas especi asian countri obes relat genet variant identifi explain littl variat bmi recent studi report associ dna methyl obes most non asian popul | D015992 | T201 |
34,670,600 | efficaci express help adult hematolog cancer patient undergo stem cell transplant protocol write insight strength eas wise studi two arm random control trial short sometim year hematopoiet stem cell transplant larg proport hematolog cancer patient undergo transplant report signific physic psycholog symptom reduc health relat qualiti life address survivorship problem develop low burden brief psycholog intervent call express help includ two theori evid base compon design work togeth synergist emot express write peer support write build evid prior random control trial show reduct physic symptom distress long term transplant survivor persist survivorship problem write insight strength eas wise trial evalu efficaci express help use transplant earli post transplant period symptom peak intervent could prevent develop persist symptom | D019337;D018380 | T191;T061 |
34,670,599 | thoracoscop resect bilater multipl superior mediastin neurofibroma indic surgic resect concern multipl bilater neurofibroma superior mediastinum remain controversi vascular injuri develop postop horn syndrom concern | D008482;D009456 | T191;T047;T029 |
34,670,598 | efficaci safeti dual intraven artesun plus quinin compar intraven artesun cerebr malaria tripl blind parallel multisit random control trial nigerian children dual paq trial protocol evid exist critic first h manag cerebr malaria morbid mortal rate current intraven monotherapi initi treatment cerebr malaria unaccept high combin therapi shorter cours effect medic shown improv outcom human particip treatment diseas studi outlin protocol conduct tripl blind parallel random control trial cerebr malaria use dual intraven medic compar current standard monotherapi | D000962;D037621;D016779 | T047;T121;T109 |
34,670,595 | clinic applic pulmonari vascular resist patient pulmonari arteri hypertens pulmonari arteri hypertens type malign pulmonari vascular diseas main caus increas pulmonari vascular resist due patholog chang pulmonari arteriol eventu lead right heart failur death one diagnost indic hemodynam pulmonari vascular resist play irreplac role pathophysiolog diagnosi treatment pulmonari arteri hypertens provid refer evalu pulmonari arteri hypertens patient articl summar clinic applic pulmonari vascular resist patient pulmonari arteri hypertens | D006976;D000081029 | T047;T046 |
34,670,594 | antimicrobi stewardship measur cardiac surgeri impact surgic site infect goal studi monitor complianc impact protocol chang surgic antimicrobi prophylaxi cardiac surgeri favour cefazolin instead cefuroxim initi hospit antimicrobi stewardship team | D000073602;D006348 | T058;T061 |
34,670,593 | esthet function reconstruct larg mandibular defect use free fibula flap implant retain prosthet case seri long term follow reconstruct rehabilit manag larg mandibular defect basal continu challeng mani respect especi vertic dimens free fibula flap utilis effici approach indic aim case seri demonstr use long term success | D015921;D005360 | T023;T074 |
34,670,592 | polymethyl methacryl cure time simul vivo total knee arthroplasti versus vitro condit present mean confirm cure intra oper polymethyl methacryl pmma cement wait remaind cement harden knowledg avail techniqu determin precis moment cure vivo cement beneath tibial tray studi use novel mean determin cement cure time two environ one environ repres oper theater environ attempt model cement condit tibial tray surgeri | D019645 | T061 |
34,670,591 | qualiti life phonatori morpholog outcom cognit unimpair adolesc pierr robin sequenc cross section studi patient pierr robin sequenc prs heterogen condit involv retro micro gnathia glossoptosi upper airway obstruct often posterior cleft palat patient prs either isol associ stickler syndrom good intellectu prognosi nevertheless qualiti life adolesc phonatori morpholog outcom rare analys assess phonatori morpholog outcom cognit unimpair adolesc prs studi oral cohip sf vocal vhi generic qualiti life qol kidscreen search determin outcom | D003240;D010855 | T047;T019 |
34,670,586 | propiti tempor chang clinic outcom transcathet compar surgic aortic valv replac meta analysi patient treatment symptomat sever aortic stenosi rapid evolv past decad transcathet tavr surgic aortic valv replac savr result report improv clinic outcom oper experi technic improv improv outcom especi patient undergo tavr sought determin compar year outcom use contemporari meta analysi | D001024;D006350;D019918;D065467 | T074;T047;T061 |
34,670,585 | identifi hub gene immun infiltr osteoarthr use comprehens bioinformat analysi osteoarthr oa common chronic degen joint disord global character synov cartilag degener joint space stenosi sub cartilag bone hyperplasia howev pathophysiolog mechan oa thorough investig | D019295;D010003 | T091;T047 |
34,670,582 | cost impact procalcitonin guid decis make durat antibiot therapi suspect earli onset sepsi neonat larg intern random control neopin trial show procalcitonin pct guid decis make superior standard care reduc durat antibiot therapi hospit neonat suspect earli onset sepsi eo without increas advers event studi aim perform cost minim studi neopin trial compar health care cost standard care pct guid decis make base neopin algorithm analyz subgroup base countri risk categori gestat age | D000900;D000066491;D000081206;D017048;D018805 | T047;T121;T079;T046;T195;T060;T081 |
34,670,581 | doubl jeopardi covid pandem risk exposur incom loss portug increas evid indic first wave covid pandem immedi health social impact disproportion affect certain socioeconom group assess inequ risk exposur advers face pandem critic inform target action effect prevent disproportion spread reduc social health inequ studi examin socioeconom mental health characterist individu work workplac thus increas risk covid exposur ii individu incom loss result pandem across socioeconom subgroup work popul first confin portug | D000086382;D058873 | T047;T067 |
34,670,580 | trend healthcar expenditur resourc util among nation repres popul opioid unit state serial cross section studi previous report healthcar cost expenditur associ popul prescrib opioid primarili focus popul chronic use opioid opioid use disord howev studi character healthcar expenditur cost among wider number peopl prescrib opioid nation repres popul unavail sought character healthcar cost expenditur associ popul prescrib opioid us | D000701;D005102 | T131;T121;T109;T081 |
34,670,577 | newer generat straight humer nail allow faster bone heal better function outcom mid term although proxim diaphys humerus fractur frequent optim manag remain controversi antegrad nail prevent damag soft tissu vascular associ postop shoulder pain dysfunct latest year straight nail design develop minim problem | D001858 | T074 |
34,670,576 | preval characterist distribut hpv genotyp women zhejiang provinc evalu understand preval hpv genotyp characterist femal popul specif area relationship cervic lesion effect guid cervic cancer screen formul hpv vaccin prevent strategi | D030361;D002583 | T191;T047 |
34,670,575 | percept adolesc pregnanc rural context colombian arm conflict qualit approach base social determin health adolesc pregnanc rural area persist health problem still proper understood studi qualit perspect address phenomenon complex social process involv recognit voic actor involv analysi specif context take place limit | D011253;D000074384 | T040;T033;T032 |
34,670,574 | myocardi strain assess use cardiovascular magnet reson imag recipi implant cardiovert defibril cardiovascular magnet reson cmr increas use evalu patient potenti candid implant cardiovert defibril icd therapi assess left ventricular lv eject fraction lvef myocardi fibrosi etiolog cardiomyopathi unclear whether cmr deriv strain measur predict appropri shock death among patient receiv icd evalu prognost valu lv strain paramet featur track ft cmr patient underw subsequ icd implant primari secondari prevent sudden cardiac death | D017147 | T074 |
34,670,573 | exercis induc irregular right heart flow dynam adolesc young adult born preterm preterm birth link elev risk heart failur cardiopulmonari diseas later life improv neonat care surviv infant born preterm reach adulthood studi use flow cardiovascular magnet reson cmr coupl exercis challeng assess impact preterm birth right heart flow dynam otherwis healthi adolesc young adult born preterm | D047928 | T046 |
34,670,572 | endogen assess myocardi injuri singl shot model base non rigid motion correct rho map cardiovascular magnet reson map may detect myocardi injuri without exogen contrast agent howev multipl co regist acquisit requir lack robust motion correct limit clinic translat introduc singl breath hold myocardi map method includ model base non rigid motion correct | D003287;D009203 | T130;T047 |
34,670,571 | associ thyroid dysfunct type diabet meta analysi prospect observ studi diabet mellitus thyroid diseas two area broad interest field endocrinolog metabol variat thyroid hormon concentr even within normal rang may portend onset type diabet mellitus tdm especi among prediabet howev current evid mix | D003924;D013959 | T047 |
34,670,570 | govern industri involv non communic diseas respons kenya low middl incom countri lmic multin compani becom increas involv address public health challeng deal compani partner health sector develop creat new challeng govern sought develop approach assess exist effect govern structur ensur industri led public health initi contribut develop | D000073296 | T047 |
34,670,569 | factor associ prolong post oper acut care length stay limb amput patient saskatchewan canada effect predispos factor post oper acut care length stay poalo lower extrem amput lea spars studi report larg focus major throughproxim ankl lea specif due diabet mellitus dm although valuabl narrow focus disregard impact caus minor level distal ankl lea address gap studi aim identifi predispos factor associ prolong poalo index lea stratifi amput level saskatchewan | D000671;D003920 | T047;T061 |
34,670,568 | experiment comput model signatur biomark discoveri renal cell carcinoma progress renal cell carcinoma rcc difficult treat year surviv rate metastat patient main reason therapi failur lack valid biomark scarc knowledg biolog process occur rcc progress thus investig mechan regul rcc progress fundament improv rcc therapi | D014408;D004198;D008954 | T201;T075;T123 |
34,670,567 | communiti base program reduc acut rheumat fever rheumat heart diseas northern australia australia north aborigin peopl live world high rate rheumat heart diseas rhd precursor acut rheumat fever arf driven social environment determin health undertook program work strengthen rhd primordi primari prevent use model address six domain hous environment support communiti awar empower health literaci health educ servic integr health navig health provid educ aim determin model experienc studi particip | D012213;D012214 | T047 |
34,670,566 | statist shape model qualiti assur measur treatment complex midfac fractur case control studi complex bilater midfac fractur necessit surgic challeng procedur preserv restor occlus sensit eye area case control studi aim show potenti statist shape model ssm measur qualiti midfac reconstruct compar estim preoper situat | D005151 | T037 |
34,670,565 | need blueprint resid creativ write workshop inpati rotat narrat medicin may mitig physician burnout increas empathi self compass encourag physician deepli connect patient storiesexperi howev narrat medicin difficult implement hectic inpati teach servic often emot tax resid | D002055;D007396 | T097;T065;T048 |
34,670,564 | explor driver barrier util communiti client led art deliveri model south western uganda patient health worker experi effort accommod grow number hiv client improv retent care reduc health care burden differenti servic deliveri dsd model introduc one model communiti client led art deliveri cclad roll uganda extent util model fulli studi aim studi explor patient health worker experi util cclad model bwizibwera health centr iv south western uganda | D015658 | T047 |
34,670,563 | contribut public health polici healthcar qualiti gender gap countri differ life expect uk mani high incom countri life expect le increas women outliv men gender gap le ggle explain biolog factor healthi behaviour health status sociodemograph characterist littl attent paid role public health polici includeaffect factor studi aim assess contribut avoid caus death measur public health polici healthcar qualiti impact ggle tempor chang uk also estim contribut avoid caus death gap le countri uk | D006291;D008017 | T081;T089;T068;T102 |
34,670,562 | surviv thrive meta ethnographi experi healthcar staff care person covid emerg coronavirus diseas heighten experi emot burden among healthcar staff guid develop support programm review sought aggreg synthesis qualit studi establish compar understand experi healthcar staff care person diseas | D000086382 | T047;T067 |
34,670,561 | telephon deliv health behaviour chang support peopl mental health condit coach perspect peopl mental health condit experi greater preval chronic diseas reduc life expect compar general popul modifi health risk behaviour physic inact poor nutrit major contribut factor popul level health coach deliv behaviour chang support via telephon healthi eat physic activ weight manag opportun utilis group support improv healthi lifestyl behaviour health coach offer valuabl perspect provis servic high risk group studi aim qualit explor coach experi provid support particip consid factor may contribut engag outcom potenti inform futur servic improv | D001523;D008603 | T048;T041 |
34,670,560 | percept behaviour attitud toward smoke held male partner chines pregnant women qualit studi direct associ tobacco exposur pregnanc pregnanc complic advers birth outcom proven previous studi suggest expect child provid valuabl opportun promot behaviour chang smoke cessat among male partner pregnant women thorough understand chines expect father smoke behaviour transit fatherhood prerequisit develop appropri intervent facilit smoke cessat studi aim explor percept behaviour attitud relat smoke among male partner pregnant women china | D005220;D037841 | T098;T099 |
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