anchor_id stringlengths 8 8 | anchor_title stringlengths 22 248 | anchor_abstract stringlengths 73 4.05k | positive_pool listlengths 1 1 | negative_pool listlengths 1 1 |
|---|---|---|---|---|
23195316 | Opportunities for bioinformatics in the classification of behavior and psychiatric disorders. | A bioinformatics approach to behavioral neuroscience provides both unique opportunities and challenges for research on behavior. A major challenge has been to describe, define, and discriminate among abstract behavioral processes, in large part by distinguishing among the biological mechanisms of unique but not entirel... | [
[
"10378865",
"Neurokinin type-1 receptor antagonist inhibits enhancement of T cell functions by substance P in normal and neuromanipulated capsaicin-treated rats.",
"Substance P (SP) plays a major role in the regulation of the interaction between immune and nervous systems. SP administration stimulates... | [
[
"23372986",
"Experience with multimodality telepathology at the University of Pittsburgh Medical Center.",
"Several modes of telepathology exist including static (store-and-forward), dynamic (live video streaming or robotic microscopy), and hybrid technology involving whole slide imaging (WSI). Telepa... |
23233683 | Changing the face of learning: ebrain and UCL distance learning diploma in clinical neurology. | ebrain is a groundbreaking e-learning program.(1) It is an exciting and novel interactive online program in clinical neuroscience aimed at hospital trainees, consultants in neurology, and other neuroscience specialties. ebrain was developed in partnership with the Joint Neuroscience Council (JNC), University College Lo... | [
[
"11807554",
"Humans integrate visual and haptic information in a statistically optimal fashion.",
"When a person looks at an object while exploring it with their hand, vision and touch both provide information for estimating the properties of the object. Vision frequently dominates the integrated visu... | [
[
"23098597",
"Affective neuroscience: Food 'wanting' hotspot in dorsal striatum.",
"New research has uncovered a micro-domain within dorsal neostriatum where enkephalin surges are triggered by the opportunity to consume tasty foods and where μ-opioid microinjections generate intense motivational ... |
23201859 | Exposure therapy in eating disorders revisited. | Exposure therapy is a widely used and effective form of treatment in anxiety disorders and addictions but evidence for its usefulness in eating disorders (ED) is inconsistent. This paper systematically reviews the literature on the use of exposure therapy in ED, the theory underpinning its use, and the deficits in curr... | [
[
"15371227",
"Specific non-coplanar PCB-mediated modulation of bottlenose dolphin and beluga whale phagocytosis upon in vitro exposure.",
"Contaminant-induced immunosuppression by organochlorines (OC), particularly polychlorinated biphenyls (PCBs), has been suspected as a cofactor in the deaths of thou... | [
[
"22998948",
"Glucocorticoid excess and the developmental origins of disease: two decades of testing the hypothesis--2012 Curt Richter Award Winner.",
"Low birthweight, a marker of an adverse in utero environment, is associated with cardiometabolic disease and brain disorders in adulthood. The adaptive... |
22850833 | Complex biomedical systems: from basic science to translation. | The Department of Biomedical Engineering (BME) of the University of Southern California (BME@USC) has a longstanding tradition of advancing biomedicine through the development and application of novel engineering ideas. More than 80 primary and affiliated faculty members conduct cutting-edge research in a wide variety ... | [
[
"486593",
"A mathematical theory of visual hallucination patterns.",
"Neuronal activity in a two-dimensional net is analyzed in the neighborhood of an instability. Bifurcation theory and group theory are used to demonstrate the existence of a variety of doubly-periodic patterns, hexagons, rolls, etc.,... | [
[
"22481743",
"Brain enabled by next-generation neurotechnology: using multiscale and multimodal models.",
"As many articles in this issue of IEEE Pulse demonstrate, interfacing directly with the brain presents several fundamental challenges. These challenges reside at multiple levels and span many disc... |
23391873 | Molecular neuroeconomics of crime and punishment: implications for neurolaw. | Criminal behaviors have been associated with risk, time and social preferences in economics (Becker 1968; Davis 1988), criminology (Chamlin & Cochran 1997), and neurolaw (Goodenough & Tucker 2010). This study proposes a molecular neuroeconomic framework for the investigation into crime and punishment. Neuroecon... | [
[
"19005051",
"Light-induced rescue of breathing after spinal cord injury.",
"Paralysis is a major consequence of spinal cord injury (SCI). After cervical SCI, respiratory deficits can result through interruption of descending presynaptic inputs to respiratory motor neurons in the spinal cord. Expressio... | [
[
"22287251",
"Towards a healthy human model of neural disorders of movement.",
"A quantitative approach to virtual-lesion physiology is presented which integrates event-related fMRI, image-guided, repetitive, transcranial magnetic stimulation (irTMS), and simultaneous recording of 3-D movement kinemati... |
22925211 | Developmental neurotoxicity testing: scientific approaches towards the next generation to protect the developing nervous system of children. An overview of the Developmental Neurotoxicity Symposium in 2011. | The Developmental Neurotoxicology (DNT) Committee has been working to promote developmental neurotoxicology and related scientific areas of interest to integrate academic and regulatory sciences in this field since the Behavioral Teratology Meeting was established by the Japanese Teratology Society in 1982. The committ... | [
[
"21563266",
"Programmed neuronal cell death induced by HIV-1 tat and methamphetamine.",
"Apoptosis and autophagy are the two major types of programmed cell death (PCD) in neurons. Homeostatic autophagy often precedes apoptosis, and when apoptosis is blocked, the failure to keep homeostasis will lead t... | [
[
"22905274",
"Toxocariasis and epilepsy: systematic review and meta-analysis.",
"Human toxocariasis is a zoonotic infection caused by the larval stages of Toxocara canis (T. canis) and less frequently Toxocara cati (T. cati). A relationship between toxocariasis and epilepsy has been hypothesized. We co... |
23166484 | Functional connectivity and tuning curves in populations of simultaneously recorded neurons. | How interactions between neurons relate to tuned neural responses is a longstanding question in systems neuroscience. Here we use statistical modeling and simultaneous multi-electrode recordings to explore the relationship between these interactions and tuning curves in six different brain areas. We find that, in most ... | [
[
"20036713",
"Behavior and serotonergic disorders in rats exposed prenatally to valproate: a model for autism.",
"In order to explore whether some aspects of the autistic phenotype could be related to impairment of the serotonergic system, we chose an animal model which mimics a potential cause of auti... | [
[
"23666281",
"[What can microscopy teach us on suicide?].",
"The fine neuroanatomy of mood disorders and suicide is a relatively recent field of investigation. Together with neuroimaging, molecular biology and biochemistry, histological analyses of post-mortem brain regions implicated in mood regulatio... |
22255837 | Physiological cognitive state assessment: applications for designing effective human-machine systems. | Significant growth in the field of neuroscience has occurred over the last decade such that new application areas for basic research techniques are opening up to practitioners in many other areas. Of particular interest to many is the principle of neuroergonomics, by which the traditional work in neuroscience and its r... | [
[
"18491163",
"Population vector code: a geometric universal as actuator.",
"The population vector code relates directional tuning of single cells and global, directional motion incited by an assembly of neurons. In this paper three things are done. First, we analyze the population vector code as a pure... | [
[
"20579637",
"Argentina's early contributions to the understanding of frontotemporal lobar degeneration.",
"Over a 100 years have passed since Pick's description of what is now termed frontotemporal lobar degeneration (FTLD). FTLD is a topic of intense current research interest yet some relevant contri... |
23981756 | Incidence and prevalence of idiopathic inflammatory myopathies in South Australia: a 30-year epidemiologic study of histology-proven cases. | To describe the epidemiology of biopsy-proven idiopathic inflammatory myopathies (IIM) in South Australia (SA).</AbstractText Cases of IIM were ascertained by review of all muscle biopsy reports from the Neuropathology Laboratory, Hanson Institute (wherein all adult muscle biopsies in SA are reported) from 1980 to 2009... | [
[
"21312401",
"Functional brain imaging in schizophrenia: selected results and methods.",
"Functional brain imaging studies of patients with schizophrenia may be grouped into those that assume that the signs and symptoms of schizophrenia are due to disordered circuitry within a critical brain region and... | [
[
"23174433",
"When do people cooperate? The neuroeconomics of prosocial decision making.",
"Understanding the roots of prosocial behavior is an interdisciplinary research endeavor that has generated an abundance of empirical data across many disciplines. This review integrates research findings from di... |
23214292 | Neuroprostheses for increasing disabled patients' mobility and control. | Neuroprostheses are electronic devices using electrophysiological signals to stimulate muscles, electronic/ mechanical devices such as substitutes for limbs or parts of limbs, or computers. The development of neuroprostheses was possible thanks to advances in understanding of the physiology of the human brain and in th... | [
[
"486593",
"A mathematical theory of visual hallucination patterns.",
"Neuronal activity in a two-dimensional net is analyzed in the neighborhood of an instability. Bifurcation theory and group theory are used to demonstrate the existence of a variety of doubly-periodic patterns, hexagons, rolls, etc.,... | [
[
"23476081",
"Framing Nicotine Addiction as a \"Disease of the Brain\": Social and Ethical Consequences.",
"In this article, we seek to better understand how a genomic vision of addiction may influence drug prevention and treatment. Though <i We explore the emerging view of addiction as a \"disease of ... |
23055474 | The Hodgkin-Huxley heritage: from channels to circuits. | The Hodgkin-Huxley studies of the action potential, published 60 years ago, are a central pillar of modern neuroscience research, ranging from molecular investigations of the structural basis of ion channel function to the computational implications at circuit level. In this Symposium Review, we aim to demonstrate the ... | [
[
"21563266",
"Programmed neuronal cell death induced by HIV-1 tat and methamphetamine.",
"Apoptosis and autophagy are the two major types of programmed cell death (PCD) in neurons. Homeostatic autophagy often precedes apoptosis, and when apoptosis is blocked, the failure to keep homeostasis will lead t... | [
[
"23195123",
"Text-mining and neuroscience.",
"The wealth and diversity of neuroscience research are inherent characteristics of the discipline that can give rise to some complications. As the field continues to expand, we generate a great deal of data about all aspects, and from multiple perspectives,... |
23293621 | Combination Across Domains: An MEG Investigation into the Relationship between Mathematical, Pictorial, and Linguistic Processing. | Debates surrounding the evolution of language often hinge upon its relationship to cognition more generally and many investigations have attempted to demark the boundary between the two. Though results from these studies suggest that language may recruit domain-general mechanisms during certain types of complex process... | [
[
"15831717",
"Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo.",
"Microglial cells represent the immune system of the mammalian brain and therefore are critically involved in various injuries and diseases. Little is known about their role in the healthy brain and th... | [
[
"23227112",
"A Social Neuroscience Perspective on Stress and Health.",
"Psychological stress is a major risk factor for the development and progression of a number of diseases, including cardiovascular disease, cancer, arthritis, and major depression. A growing body of research suggests that long-term... |
22622246 | [The language disorders in schizophrenia in neurolinguistic and psycholinguistic perspectives]. | The descriptive psychopathology has classically equated the language with the formal aspects of thought. Recent developments in experimental and clinical research have emphasized the study of the language as a specific communicative ability. Within the framework of cognitive neuropsychology, the development of innovati... | [
[
"12077007",
"Neural systems underlying British Sign Language and audio-visual English processing in native users.",
"In order to understand the evolution of human language, it is necessary to explore the neural systems that support language processing in its many forms. In particular, it is informativ... | [
[
"22105777",
"Emerging roles of p53 in glial cell function in health and disease.",
"Emerging evidence suggests that p53, a tumor suppressor protein primarily involved in cancer biology, coordinates a wide range of novel functions in the CNS including the mediation of pathways underlying neurodegenerat... |
23195123 | Text-mining and neuroscience. | The wealth and diversity of neuroscience research are inherent characteristics of the discipline that can give rise to some complications. As the field continues to expand, we generate a great deal of data about all aspects, and from multiple perspectives, of the brain, its chemistry, biology, and how these affect beha... | [
[
"12951145",
"Structure and function of the vomeronasal system: an update.",
"Several developments during the past 15 years have profoundly affected our understanding of the vomeronasal system (VNS) of vertebrates. In the mid 1990s, the vomeronasal epithelium of mammals was found to contain two populat... | [
[
"23248404",
"Neuroprotective activity of Stereospermum suaveolens DC against 6-OHDA induced Parkinson's disease model.",
"To evaluate the neuroprotective effect of Stereospermum suaveolens DC on 6-hydroxy dopamine induced Parkinson's disease model.</AbstractText The study was conducted on Sprague-Dawl... |
22553016 | Interactions between behaviorally relevant rhythms and synaptic plasticity alter coding in the piriform cortex. | Understanding how neural and behavioral timescales interact to influence cortical activity and stimulus coding is an important issue in sensory neuroscience. In air-breathing animals, voluntary changes in respiratory frequency alter the temporal patterning olfactory input. In the olfactory bulb, these behavioral timesc... | [
[
"17457312",
"The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression.",
"Beside the well-known deficiency in serotonergic neurotransmission as pathophysiological correlate of major depression (MD), recent evidence points to a pivotal role of increased glutam... | [
[
"23095170",
"High yield derivation of enriched glutamatergic neurons from suspension-cultured mouse ESCs for neurotoxicology research.",
"Recently, there has been a strong emphasis on identifying an in vitro model for neurotoxicity research that combines the biological relevance of primary neurons wit... |
23200550 | Next generation sequencing for neurological diseases: new hope or new hype? | Over the past year huge advances have been made in our ability to determine the genetic aetiology of many neurological diseases through the utilisation of next generation sequencing platforms. This technology is, on a daily basis, providing new breakthroughs in neurological disease. The aim of this article is to clearl... | [
[
"21312401",
"Functional brain imaging in schizophrenia: selected results and methods.",
"Functional brain imaging studies of patients with schizophrenia may be grouped into those that assume that the signs and symptoms of schizophrenia are due to disordered circuitry within a critical brain region and... | [
[
"37539014",
"Quantification of Speech Disfluency as a Marker of Medication-Induced Cognitive Impairment: An Application of Computerized Speech Analysis in Neuropharmacology.",
"We present the results of a study investigating the use of speech and language characteristics extracted from spontaneous spo... |
23493457 | Collaborative online writing assignments to foster active learning. | To help students master the content of a neurophysiology course, they were asked to participate in collaborative writing projects. In the first two years, students contributed to a class wiki by summarizing one lecture and editing summaries of several others. In the second two years, students worked in teams of three o... | [
[
"21325527",
"Emergence of learned categorical representations within an auditory forebrain circuit.",
"Many learned behaviors are thought to require the activity of high-level neurons that represent categories of complex signals, such as familiar faces or native speech sounds. How these complex, exper... | [
[
"23293621",
"Combination Across Domains: An MEG Investigation into the Relationship between Mathematical, Pictorial, and Linguistic Processing.",
"Debates surrounding the evolution of language often hinge upon its relationship to cognition more generally and many investigations have attempted to demar... |
23269483 | Metabolomic analysis of cerebrospinal fluid indicates iron deficiency compromises cerebral energy metabolism in the infant monkey. | Iron deficiency anemia affects many pregnant women and young infants worldwide. The health impact is significant, given iron's known role in many body functions, including oxidative and lipid metabolism, protein synthesis and brain neurochemistry. The following research determined if (1)H NMR spectroscopy-based metabol... | [
[
"21391760",
"The default network distinguishes construals of proximal versus distal events.",
"Humans enjoy a singular capacity to imagine events that differ from the \"here-and-now.\" Recent cognitive neuroscience research has linked such simulation processes to the brain's \"default network.\" Howev... | [
[
"37539014",
"Quantification of Speech Disfluency as a Marker of Medication-Induced Cognitive Impairment: An Application of Computerized Speech Analysis in Neuropharmacology.",
"We present the results of a study investigating the use of speech and language characteristics extracted from spontaneous spo... |
25103077 | Clinical and electrophysiologic features of childhood Guillain-Barré syndrome in Northeast China. | Since little has been reported in previous studies, we aimed to find the clinical and electrophysiologic characteristics associated with childhood Guillain-Barré Syndrome (GBS) in Northeast China.</AbstractText The clinical and electrophysiologic data were collected and reviewed retrospectively in 33 children and ... | [
[
"22240730",
"Birdsong neurolinguistics: songbird context-free grammar claim is premature.",
"There are remarkable behavioral, neural, and genetic similarities between song learning in songbirds and speech acquisition in human infants. Previously, we have argued that this parallel cannot be extended to... | [
[
"22843835",
"The Lourdes medical cures revisited.",
"This article examines the cures recorded in Lourdes, France, between 1858, the year of the Visions, and 1976, the date of the last certified cure of the twentieth century. Initially, the records of cures were crude or nonexistent, and allegations of... |
23024632 | How anatomy shapes dynamics: a semi-analytical study of the brain at rest by a simple spin model. | Resting state networks (RSNs) show a surprisingly coherent and robust spatiotemporal organization. Previous theoretical studies demonstrated that these patterns can be understood as emergent on the basis of the underlying neuroanatomical connectivity skeleton. Integrating the biologically realistic DTI/DSI-(Diffusion T... | [
[
"11488376",
"Fears, phobias, and preparedness: toward an evolved module of fear and fear learning.",
"An evolved module for fear elicitation and fear learning with 4 characteristics is proposed. (a) The fear module is preferentially activated in aversive contexts by stimuli that are fear relevant in a... | [
[
"23504612",
"An undergraduate laboratory exercise examining the psychomotor stimulant effects of caffeine in laboratory rats.",
"This paper describes an exercise in a Systems and Behavioral Neuroscience with Laboratory class, an introductory laboratory class taken by Barnard College students majoring ... |
22226506 | Luteolin enhances cholinergic activities in PC12 cells through ERK1/2 and PI3K/Akt pathways. | Luteolin, a 3', 4', 5, 7-tetrahydroxyflavone, is an active compound in Rosmarinus officinalis (Lamiacea), and has been reported to exert several benefits in neuronal cells. However cholinergic-induced activities of luteolin still remain unknown. Neuronal differentiation encompasses an elaborate developmental program wh... | [
[
"21731699",
"Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain.",
"Recent discovery of 5-hydroxymethylcytosine (5hmC) in genomic DNA raises the question how this sixth base is recognized by cellular proteins. In contrast to the methyl-CpG binding domain (MBD) of MeCP2, we found that the S... | [
[
"23233683",
"Changing the face of learning: ebrain and UCL distance learning diploma in clinical neurology.",
"ebrain is a groundbreaking e-learning program.(1) It is an exciting and novel interactive online program in clinical neuroscience aimed at hospital trainees, consultants in neurology, and oth... |
23447793 | A future without chronic pain: neuroscience and clinical research. | Chronic pain affects 1.5 billion people worldwide, an estimated 100 million of whom live in the United States. Yet we currently have no effective treatment options. Fortunately, writes David Borsook, director of the Pain and Imaging Neuroscience Group at Children's Hospital Boston, Massachusetts General Hospital, and M... | [
[
"9626715",
"The role of defeat and entrapment (arrested flight) in depression: an exploration of an evolutionary view.",
"The social rank theory of psychopathology suggests that with the evolution of social hierarchies various psychobiological mechanisms became attuned to the success or failure in con... | [
[
"23576843",
"Possibilities offered by implantable miniaturized cuff-electrodes for insect neurophysiology.",
"Recent advances in microsystems technology led to a miniaturization of cuff-electrodes, which suggests these electrodes not just for long-term neuronal recordings in mammalians, but also in me... |
23262120 | Tianeptine modulates amygdalar glutamate neurochemistry and synaptic proteins in rats subjected to repeated stress. | Stress is a common environmental factor associated with depressive illness and the amygdala is thought to be integral for this association. For example, repeated stress impairs amygdalar neuroplasticity in rodents and these defects parallel amygdalar deficits in depressive illness patients. Because the excitatory neuro... | [
[
"22708717",
"No evidence of intelligence improvement after working memory training: a randomized, placebo-controlled study.",
"Numerous recent studies seem to provide evidence for the general intellectual benefits of working memory training. In reviews of the training literature, Shipstead, Redick, an... | [
[
"23167712",
"Affect-specific modulation of the N1m to shock-conditioned tones: magnetoencephalographic correlates.",
"Despite its fundamental relevance for representing the emotional world surrounding us, human affective neuroscience research has widely neglected the auditory system, at least in compa... |
23494064 | A structured-inquiry approach to teaching neurophysiology using computer simulation. | Computer simulation is a valuable tool for teaching the fundamentals of neurophysiology in undergraduate laboratories where time and equipment limitations restrict the amount of course content that can be delivered through hands-on interaction. However, students often find such exercises to be tedious and unstimulating... | [
[
"15051143",
"Vasopressin-dependent neural circuits underlying pair bond formation in the monogamous prairie vole.",
"Arginine vasopressin and its V1a receptor subtype (V1aR) are critical for pair bond formation between adult prairie voles. However, it is unclear which brain circuits are involved in th... | [
[
"23195310",
"Model organism databases in behavioral neuroscience.",
"Model Organism Databases (MODs) are an important informatics tool for researchers. They provide comprehensive organism specific genetic, genomic, and phenotype datasets. MODs ensure accurate data identification and integrity and prov... |
23175678 | The role of the medial prefrontal cortex in social categorization. | Group membership is an important aspect of our everyday behavior. Recently, we showed that existing relevant in-group labels increased activation in the medial prefrontal cortex (MPFC) compared with out-group labels, suggesting a role of the MPFC in social categorization. However, the question still remains whether thi... | [
[
"12060992",
"Quantification of brain lesions using interactive automated software.",
"We developed an interactive program, Analysis of Brain Lesions (ABLe) so that researchers studying the effects of brain lesions on cognition could have a user-friendly tool that could quantitatively characterize such... | [
[
"23347558",
"A new method for automated high-dimensional lesion segmentation evaluated in vascular injury and applied to the human occipital lobe.",
"Making robust inferences about the functional neuroanatomy of the brain is critically dependent on experimental techniques that examine the consequences... |
22911883 | Maternal and fetal antibrain antibodies in development and disease. | Recent evidence has emerged indicating that the maternal immune response can have a substantial deleterious impact on prenatal development (Croen et al., [2008]: Biol Psychiatry 64:583-588). The maternal immune response is largely sequestered from the fetus. Maternal antibodies, specifically immunoglobulin G (IgG), are... | [
[
"19874855",
"Species differences in group size and electrosensory interference in weakly electric fishes: implications for electrosensory processing.",
"In animals with active sensory systems, group size can have dramatic effects on the sensory information available to individuals. In \"wave-type\" we... | [
[
"24294562",
"Dorello's Canal and Gruber's Ligament: Historical Perspective.",
"Wenzel Leopold Gruber and Primo Dorello were great anatomists and researchers during the 19th and 20th centuries. Their contributions to neuroanatomy-namely the Gruber's (petrosphenoidal) ligament and Dorello's canal, respe... |
22998948 | Glucocorticoid excess and the developmental origins of disease: two decades of testing the hypothesis--2012 Curt Richter Award Winner. | Low birthweight, a marker of an adverse in utero environment, is associated with cardiometabolic disease and brain disorders in adulthood. The adaptive changes made by the fetus in response to the intra-uterine environment result in permanent changes in physiology, structure and metabolism, a phenomenon termed early li... | [
[
"18457512",
"Timing, storage, and comparison of stimulus duration engage discrete anatomical components of a perceptual timing network.",
"The temporal discrimination paradigm requires subjects to compare the duration of a probe stimulus to that of a sample previously stored in working or long-term me... | [
[
"23280856",
"Intrahippocampal infusion of the Ih blocker ZD7288 slows evoked theta rhythm and produces anxiolytic-like effects in the elevated plus maze.",
"Hippocampal theta rhythm has been associated with a number of behavioral processes, including learning and memory, spatial behavior, sensorimotor... |
22367250 | A 3-dimensional digital atlas of the ascending sensory and the descending motor systems in the pigeon brain. | Pigeons are classic animal models for learning, memory, and cognition. The majority of the current understanding about avian neurobiology outside of the domain of the song system has been established using pigeons. Since MRI represents an increasingly relevant tool for comparative neuroscience, a 3-dimensional MRI-base... | [
[
"16413796",
"Meta-analyzing left hemisphere language areas: phonology, semantics, and sentence processing.",
"The advent of functional neuroimaging has allowed tremendous advances in our understanding of brain-language relationships, in addition to generating substantial empirical data on this subject... | [
[
"23261405",
"The neurobiology of depression and antidepressant action.",
"We present a comprehensive overview of the neurobiology of unipolar major depression and antidepressant drug action, integrating data from affective neuroscience, neuro- and psychopharmacology, neuroendocrinology, neuroanatomy, ... |
23041373 | Developmental treatment with bisphenol A causes few alterations on measures of postweaning activity and learning. | Widespread bisphenol A (BPA) exposure necessitates increased knowledge of its potential effects for better risk assessment and regulatory guidance. Here, female Sprague-Dawley rats, reared in low exogenous estrogen environments and bred at adulthood, were gavaged on gestational days 6-21 with vehicle (VEH), 2.5 or 25.0... | [
[
"22708717",
"No evidence of intelligence improvement after working memory training: a randomized, placebo-controlled study.",
"Numerous recent studies seem to provide evidence for the general intellectual benefits of working memory training. In reviews of the training literature, Shipstead, Redick, an... | [
[
"23505339",
"Baby Steps to Superintelligence: Neuroprosthetics and Children.",
"Children surviving neural injuries face challenges not seen by their adult counterparts, namely that they experience neural injury before reaching neurodevelopmental maturity. Neural prostheses offer one possible path to r... |
20579637 | Argentina's early contributions to the understanding of frontotemporal lobar degeneration. | Over a 100 years have passed since Pick's description of what is now termed frontotemporal lobar degeneration (FTLD). FTLD is a topic of intense current research interest yet some relevant contributions by non-English speaking authors have received little attention, which makes the history of FTLD research incomplete. ... | [
[
"21896369",
"The size and burden of mental disorders and other disorders of the brain in Europe 2010.",
"To provide 12-month prevalence and disability burden estimates of a broad range of mental and neurological disorders in the European Union (EU) and to compare these findings to previous estimates. ... | [
[
"22255612",
"Wirelessly powered stimulator and recorder for neuronal interfaces.",
"Functional Electrical Stimulation (FES) is widely adopted in neuro-engineering to partially alleviate diseased functions in the brain, retina and cochlea. We present a 32-channel wirelessly powered constant current sti... |
23252730 | The physiology of fish behaviour: a selective review of developments over the past 40 years(§). | During the past 40 years many new techniques have emerged that have been pivotal in furthering understanding of the physiology of fish behaviour. Behavioural studies have been enhanced by video recording systems and software for computerized event recording analysis, fine scale anatomical studies by fluorescence confoc... | [
[
"15831717",
"Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo.",
"Microglial cells represent the immune system of the mammalian brain and therefore are critically involved in various injuries and diseases. Little is known about their role in the healthy brain and th... | [
[
"22977368",
"Coping with Brain Disorders using Neurotechnology.",
"Brain disorders account for more than 34% of the global burden of disease, crippling nations by decreasing their \"mental capital\"-with greater effect in developing countries. Early detection is the key to their management, but establ... |
22997053 | Imaging depletion: fMRI provides new insights into the processes underlying ego depletion*. | 'Ego depletion' refers to the phenomenon of diminished ability to enact self-regulation with repeated efforts. Several models offer process accounts of how ego depletion works, but few studies directly investigate these processes. A study in this issue of Social, Cognitive, & Affective Neuroscience by Wagner and He... | [
[
"19915731",
"The human brain in numbers: a linearly scaled-up primate brain.",
"The human brain has often been viewed as outstanding among mammalian brains: the most cognitively able, the largest-than-expected from body size, endowed with an overdeveloped cerebral cortex that represents over 80% of br... | [
[
"23177656",
"Synthetic event-related potentials: a computational bridge between neurolinguistic models and experiments.",
"Our previous work developed Synthetic Brain Imaging to link neural and schema network models of cognition and behavior to PET and fMRI studies of brain function. We here extend th... |
23316158 | Increasing quality and managing complexity in neuroinformatics software development with continuous integration. | High quality neuroscience research requires accurate, reliable and well maintained neuroinformatics applications. As software projects become larger, offering more functionality and developing a denser web of interdependence between their component parts, we need more sophisticated methods to manage their complexity. I... | [
[
"17898773",
"The NCBI dbGaP database of genotypes and phenotypes.",
"The National Center for Biotechnology Information has created the dbGaP public repository for individual-level phenotype, exposure, genotype and sequence data and the associations between them. dbGaP assigns stable, unique identifier... | [
[
"21930285",
"The CC genotype in HTR2A T102C polymorphism is associated with behavioral impulsivity in alcohol-dependent patients.",
"High levels of impulsivity can increase the vulnerability for development of alcohol dependence. Moreover, impulsivity is considered to be a predictor of poor treatment ... |
23344988 | Towards a general model of temporal discounting. | Psychological models of temporal discounting have now successfully displaced classical economic theory due to the simple fact that many common behavior patterns, such as impulsivity, were unexplainable with classic models. However, the now dominant hyperbolic model of discounting is itself becoming increasingly straine... | [
[
"17522323",
"Time discounting for primary rewards.",
"Previous research, involving monetary rewards, found that limbic reward-related areas show greater activity when an intertemporal choice includes an immediate reward than when the options include only delayed rewards. In contrast, the lateral prefr... | [
[
"23124810",
"Cognitive mapping in humans and its relationship to other orientation skills.",
"Human orientation in novel and familiar environments is a complex skill that can involve numerous different strategies. To date, a comprehensive account of how these strategies interrelate at the behavioural ... |
23098597 | Affective neuroscience: Food 'wanting' hotspot in dorsal striatum. | New research has uncovered a micro-domain within dorsal neostriatum where enkephalin surges are triggered by the opportunity to consume tasty foods and where μ-opioid microinjections generate intense motivational 'wanting' to eat without enhancing food 'liking'.</AbstractText | [
[
"19400719",
"The science of neural interface systems.",
"The ultimate goal of neural interface research is to create links between the nervous system and the outside world either by stimulating or by recording from neural tissue to treat or assist people with sensory, motor, or other disabilities of n... | [
[
"23316158",
"Increasing quality and managing complexity in neuroinformatics software development with continuous integration.",
"High quality neuroscience research requires accurate, reliable and well maintained neuroinformatics applications. As software projects become larger, offering more functiona... |
20146613 | Language-universal sensory deficits in developmental dyslexia: English, Spanish, and Chinese. | Studies in sensory neuroscience reveal the critical importance of accurate sensory perception for cognitive development. There is considerable debate concerning the possible sensory correlates of phonological processing, the primary cognitive risk factor for developmental dyslexia. Across languages, children with dysle... | [
[
"19431278",
"Spike-timing error backpropagation in theta neuron networks.",
"The main contribution of this letter is the derivation of a steepest gradient descent learning rule for a multilayer network of theta neurons, a one-dimensional nonlinear neuron model. Central to our model is the assumption t... | [
[
"22255612",
"Wirelessly powered stimulator and recorder for neuronal interfaces.",
"Functional Electrical Stimulation (FES) is widely adopted in neuro-engineering to partially alleviate diseased functions in the brain, retina and cochlea. We present a 32-channel wirelessly powered constant current sti... |
23347558 | A new method for automated high-dimensional lesion segmentation evaluated in vascular injury and applied to the human occipital lobe. | Making robust inferences about the functional neuroanatomy of the brain is critically dependent on experimental techniques that examine the consequences of focal loss of brain function. Unfortunately, the use of the most comprehensive such technique-lesion-function mapping-is complicated by the need for time-consuming ... | [
[
"17322880",
"Mapping autism risk loci using genetic linkage and chromosomal rearrangements.",
"Autism spectrum disorders (ASDs) are common, heritable neurodevelopmental conditions. The genetic architecture of ASDs is complex, requiring large samples to overcome heterogeneity. Here we broaden coverage ... | [
[
"23231650",
"Dissociable brain signatures of choice conflict and immediate reward preferences in alcohol use disorders.",
"Impulsive delayed reward discounting (DRD) is an important behavioral process in alcohol use disorders (AUDs), reflecting incapacity to delay gratification. Recent work in neuroec... |
23237463 | Interactions between tactile and proprioceptive representations in haptics. | Neuroprosthetic limbs, regardless of their sophisticated motor control, require sensory feedback to viably interact with the environment. Toward that aim, the authors examined interrelationships between tactile and proprioceptive sensations. Through human psychophysics experiments, they evaluated error patterns of subj... | [
[
"18799683",
"Growth of white matter in the adolescent brain: role of testosterone and androgen receptor.",
"The growth of white matter during human adolescence shows a striking sexual dimorphism; the volume of white matter increases with age slightly in girls and steeply in boys. Here, we provide evid... | [
[
"23195123",
"Text-mining and neuroscience.",
"The wealth and diversity of neuroscience research are inherent characteristics of the discipline that can give rise to some complications. As the field continues to expand, we generate a great deal of data about all aspects, and from multiple perspectives,... |
23469524 | [Analysis of characteristics of alpha electroencephalogram during the interaction between emotion and cognition based on Granger causality]. | Studying the functional network during the interaction between emotion and cognition is an important way to reveal the underlying neural connections in the brain and nowadays, it has become a hot topic in cognitive neuroscience. Granger causality (GC), based on multivariate autoregressive (MVAR) model, and being able t... | [
[
"17670965",
"Cell type-specific tuning of hippocampal interneuron firing during gamma oscillations in vivo.",
"Cortical gamma oscillations contribute to cognitive processing and are thought to be supported by perisomatic-innervating GABAergic interneurons. We performed extracellular recordings of iden... | [
[
"23195119",
"Biological databases for behavioral neurobiology.",
"Databases are, at their core, abstractions of data and their intentionally derived relationships. They serve as a central organizing metaphor and repository, supporting or augmenting nearly all bioinformatics. Behavioral domains provide... |
23245548 | Family history: a guide for neurologists in the age of genomic medicine. | The field of neurogenetics has expanded dramatically over recent years. Neurogenetics has developed from a distinct subspecialty within neurology to something that transcends most of the common presenting conditions for neurologists. The importance of understanding the genetic contribution to conditions like epilepsy, ... | [
[
"23017085",
"The maps problem and the mapping problem: two challenges for a cognitive neuroscience of speech and language.",
"Research on the brain basis of speech and language faces theoretical and empirical challenges. Most current research, dominated by imaging, deficit-lesion, and electrophysiolog... | [
[
"22365959",
"Defining the genetic architecture of human developmental language impairment.",
"Language is a uniquely human trait, which poses limitations on animal models for discovering biological substrates and pathways. Despite this challenge, rapidly developing biotechnology in the field of genomi... |
23286166 | Group-wise consistent fiber clustering based on multimodal connectional and functional profiles. | Fiber clustering is an essential step towards brain connectivity modeling and tract-based analysis of white matter integrity via diffusion tensor imaging (DTI) in many clinical neuroscience applications. A variety of methods have been developed to cluster fibers based on various types of features such as geometry, anat... | [
[
"12721816",
"Dopamine D3 receptor gene polymorphism and violent behavior: relation to impulsiveness and ADHD-related psychopathology.",
"Several lines of evidence indicate that dopaminergic neurotransmission is involved in the regulation of impulsive aggression and violence and that genetically determ... | [
[
"22960226",
"Empiricists are from Venus, modelers are from Mars: Reconciling experimental and computational approaches in cognitive neuroscience.",
"We describe how computational models can be useful to cognitive and behavioral neuroscience, and discuss some guidelines for deciding whether a model is ... |
23197674 | Surface electromyography recording of spontaneous eyeblinks: applications in neuroprosthetics. | We are designing an implantable neuroprosthesis for the treatment of unilateral facial paralysis. The envisioned biomimetic device paces artificial blinks in the paretic eyelid when activity in the healthy orbicularis oculi (orbicularis) muscle is detected. The present article focuses on electromyography (EMG)-based ey... | [
[
"486593",
"A mathematical theory of visual hallucination patterns.",
"Neuronal activity in a two-dimensional net is analyzed in the neighborhood of an instability. Bifurcation theory and group theory are used to demonstrate the existence of a variety of doubly-periodic patterns, hexagons, rolls, etc.,... | [
[
"23161463",
"Recent advances in clinical neurogenetics.",
"Herein, I review the main papers in neurogenetic research published in the Journal of Neurology over the last year.</AbstractText"
]
] |
22344955 | Neurotechnology to accelerate learning: during marksmanship training. | This article explores the psychophysiological metrics during expert and novice performances in marksmanship, combat deadly force judgment and decision making (DFJDM), and interactions of teams. Electroencephalography (EEG) and electrocardiography (ECG) are used to characterize the psychophysiological profiles within al... | [
[
"21184355",
"Evidence for model-based action planning in a sequential finger movement task.",
"In this article, the authors examine whether and how humans use model-free, reflexive strategies and model-based, deliberative strategies in motor sequence learning. They asked subjects to perform the grid-s... | [
[
"23049494",
"Neuroeconomic measures of social decision-making across the lifespan.",
"Social and decision-making deficits are often the first symptoms of a striking number of neurodegenerative disorders associated with aging. These includes not only disorders that directly impact dopamine and basal ga... |
20522270 | On consciousness, resting state fMRI, and neurodynamics. | During the last years, functional magnetic resonance imaging (fMRI) of the brain has been introduced as a new tool to measure consciousness, both in a clinical setting and in a basic neurocognitive research. Moreover, advanced mathematical methods and theories have arrived the field of fMRI (e.g. computational neuroima... | [
[
"16085300",
"Reference assignment: using language breakdown to choose between theoretical approaches.",
"We report results of an experimental study with Dutch agrammatic aphasics that investigated their ability to interpret pronominal elements in transitive clauses and Exceptional Case Marking constru... | [
[
"20700045",
"Comparative neuroscience of stimulant-induced memory dysfunction: role for neurogenesis in the adult hippocampus.",
"The discovery that the addictive drugs impair neurogenesis in the adult hippocampus has prompted the elaboration of new biological hypotheses to explain addiction and drug-... |
23098592 | Behavioral neuroscience: Crawling is a no-brainer for fruit fly larvae. | How are stereotyped behaviors organized in a simple nervous system? A new study in the Drosophila larva reports that the foraging routine can be performed in the absence of any input from the brain.</AbstractText | [
[
"11222789",
"Paraplegin gene analysis in hereditary spastic paraparesis (HSP) pedigrees in northeast England.",
"To identify the frequency and characterize the phenotype of paraplegin mutations in the hereditary spastic paraparesis (HSP) population in the northeast of England.</AbstractText HSP is a d... | [
[
"23439731",
"Cerebellar pathology of a dual clinical diagnosis: patients with essential tremor and dystonia.",
"Clinical studies have implicated the cerebellum in the pathogenesis of essential tremor (ET), and recent postmortem studies have identified structural changes in the ET cerebellum. While the... |
22207847 | The evolution of syntax: an exaptationist perspective. | The evolution of language required elaboration of a number of independent mechanisms in the hominin lineage, including systems involved in signaling, semantics, and syntax. Two perspectives on the evolution of syntax can be contrasted. The "continuist" perspective seeks the evolutionary roots of complex human syntax in... | [
[
"17691351",
"An introduction to operative neuromodulation and functional neuroprosthetics, the new frontiers of clinical neuroscience and biotechnology.",
"Operative neuromodulation is the field of altering electrically or chemically the signal transmission in the nervous system by implanted devices i... | [
[
"21749991",
"Acetazolamide-responsive exercise-induced episodic ataxia associated with a novel homozygous DARS2 mutation.",
"Leukoencephalopathy with brain stem and spinal cord involvement and brain lactate elevation (LBSL) was recently shown to be caused by mutations in the DARS2 gene, encoding a mit... |
22344946 | Answering the big questions in neuroscience: DoD's experimental research wing takes on massive, high-risk projects. | When the Defense Advanced Research Projects Agency (DARPA) asks research questions, it goes big. This is, after all, the same agency that put together teams of scientists and engineers to find a way to connect the worlds computers and, in doing so, developed the precursor to the Internet. DARPA, the experimental resear... | [
[
"19298949",
"Perceptual simulation in conceptual combination: evidence from property generation.",
"In three experiments, participants received nouns or noun phrases for objects and verbally generated their properties (\"feature listing\"). Several sources of evidence indicated that participants const... | [
[
"23275858",
"Brain state-triggered stimulus delivery: An efficient tool for probing ongoing brain activity.",
"What is the relationship between variability in ongoing brain activity <i"
]
] |
20377146 | Saccadic peak velocity sensitivity to variations in mental workload. | For research and applications in the field of (neuro)ergonomics, it is of increasing importance to have reliable methods for measuring mental workload. In the present study we examined the hypothesis that saccadic eye movements can be used for an online assessment of mental workload.</AbstractText Saccadic main sequenc... | [
[
"10482383",
"MRI volume of the amygdala: a reliable method allowing separation from the hippocampal formation.",
"Studies of MRI-derived volume of the amygdala have been mostly performed on coronal sections where its boundaries with the hippocampus and the entorhinal cortex are indistinct. To date, al... | [
[
"20181553",
"Organization and physiology of posterior lateral line afferent neurons in larval zebrafish.",
"The lateral line system of larval zebrafish can translate hydrodynamic signals from the environment to guide body movements. Here, I demonstrate a spatial relationship between the organization o... |
23060781 | Using "smart stimulators" to treat Parkinson's disease: re-engineering neurostimulation devices. | Let's imagine the cruise control of your car locked at 120 km/h on any road in any condition (city, country, highway, sunny or rainy weather), or your car air conditioner set on maximum cold in any temperature condition (even during a snowy winter): would you find it efficient? That would probably not be the mos... | [
[
"16413796",
"Meta-analyzing left hemisphere language areas: phonology, semantics, and sentence processing.",
"The advent of functional neuroimaging has allowed tremendous advances in our understanding of brain-language relationships, in addition to generating substantial empirical data on this subject... | [
[
"23341313",
"Absence of verbal recall or memory for symptom acquisition in fear and trauma exposure: a conceptual case for fear conditioning and learned nonuse in assessment and treatment.",
"Absence of memory or verbal recall for symptom acquisition in fear and trauma exposure, as well as absence of ... |
20740069 | The many tunes of perisomatic targeting interneurons in the hippocampal network. | The axonal targets of perisomatic targeting interneurons make them ideally suited to synchronize excitatory neurons. As such they have been implicated in rhythm generation of network activity in many brain regions including the hippocampus. However, several recent publications indicate that their roles extend beyond th... | [
[
"22430310",
"Cloning and expression of tachykinins and their association with kisspeptins in the brains of zebrafish.",
"The tachykinins are a family of neuropeptides, including substance P (SP), neurokinin A (NKA), and neurokinin B (NKB), that are encoded by the tac1 (SP and NKA) or tac2/3 (NKB) gene... | [
[
"23853342",
"HermesD: A High-Rate Long-Range Wireless Transmission System for Simultaneous Multichannel Neural Recording Applications.",
"HermesD is a high-rate, low-power wireless transmission system to aid research in neural prosthetic systems for motor disabilities and basic motor neuroscience. It ... |
22105777 | Emerging roles of p53 in glial cell function in health and disease. | Emerging evidence suggests that p53, a tumor suppressor protein primarily involved in cancer biology, coordinates a wide range of novel functions in the CNS including the mediation of pathways underlying neurodegenerative disease pathogenesis. Moreover, an evolving concept in cell and molecular neuroscience is that gli... | [
[
"12388184",
"T cell substance P receptor governs antigen-elicited IFN-gamma production.",
"Substance P (SP) enhances antigen-dependent T cell IFN-gamma production. It was determined if a T cell neurokinin-1 receptor (NK-1R) was critical for IFN-gamma regulation. T cells from schistosome-infected mice ... | [
[
"23367102",
"Music and emotion: an EEG connectivity study in patients with disorders of consciousness.",
"Human emotion perception is a topic of great interest for both cognitive and clinical neuroscience, but its electrophysiological correlates are still poorly understood. The present study is aimed ... |
23280856 | Intrahippocampal infusion of the Ih blocker ZD7288 slows evoked theta rhythm and produces anxiolytic-like effects in the elevated plus maze. | Hippocampal theta rhythm has been associated with a number of behavioral processes, including learning and memory, spatial behavior, sensorimotor integration and affective responses. Suppression of hippocampal theta frequency has been shown to be a reliable neurophysiological signature of anxiolytic drug action in test... | [
[
"22708717",
"No evidence of intelligence improvement after working memory training: a randomized, placebo-controlled study.",
"Numerous recent studies seem to provide evidence for the general intellectual benefits of working memory training. In reviews of the training literature, Shipstead, Redick, an... | [
[
"22940423",
"HIV immune complexes prevent excitotoxicity by interaction with NMDA receptors.",
"Human immunodeficiency virus-1 (HIV)-associated neurocognitive disorder (HAND) is a neurodegenerative disease for which there is no available neuroprotective therapy. Viral proteins, such as Tat, have been ... |
23112758 | How costs influence decision values for mixed outcomes. | The things that we hold dearest often require a sacrifice, as epitomized in the maxim "no pain, no gain." But how is the subjective value of outcomes established when they consist of mixtures of costs and benefits? We describe theoretical models for the integration of costs and benefits into a single value, drawing on ... | [
[
"20427643",
"Emotional automaticity is a matter of timing.",
"There has been a long controversy concerning whether the amygdala's response to emotional stimuli is automatic or dependent on attentional load. Using magnoencephalography and an advanced beamformer source localization technique, we found t... | [
[
"22996174",
"Direct lineage conversion: induced neuronal cells and induced neural stem cells.",
"Cellular reprogramming to neural cells is an area of ongoing study in developmental neuroscience, and recent research has generated remarkable achievements. Several studies have shown that the ectopic expr... |
23413683 | [Compensatory mechanisms to heal neuroplasticity impairment under Alzheiemer's disease neurodegeneration. I: The role of amyloid beta and its' precursor protein]. | In-depth scholar literature analysis of Alzheimer's disease neurodegenerative features of amyloid beta protein neurochemistry modification and excessive phosphorylation of tau protein (and associated neuronal cytoskeleton rearrangements) are secondary phenomena. At early disease stage these neurobiochemical mechanisms ... | [
[
"20800054",
"Kisspeptins: bridging energy homeostasis and reproduction.",
"Body energy reserves and metabolic state are relevant modifiers of puberty onset and fertility; forms of metabolic stress ranging from persistent energy insufficiency to morbid obesity are frequently linked to reproductive diso... | [
[
"22284580",
"Christfried Jakob's late views (1930-1949) on the psychogenetic function of the cerebral cortex and its localization: culmination of the neurophilosophical thought of a keen brain observer.",
"This article follows the culmination of the scientific thought of the neurobiologist Christfried... |
22436435 | The developing brain: from theory to neuroimaging and back. | Surprisingly little headway has been made towards understanding how brain growth maps onto mental growth during child development. This review aims at bridging and integrating recent human neuroscientific brain maturation findings with the conceptual thinking of theorists in the behavioural tradition of studying cognit... | [
[
"15525757",
"Identification of amino acid residues in the insect sodium channel critical for pyrethroid binding.",
"The voltage-gated sodium channel is the primary target site of pyrethroids, which constitute a major class of insecticides used worldwide. Pyrethroids prolong the opening of sodium chann... | [
[
"21130996",
"Dynamics of wrist rotations.",
"Understanding the dynamics of wrist rotations is important for many fields, including biomechanics, rehabilitation and motor neuroscience. This paper provides an experimentally based mathematical model of wrist rotation dynamics in Flexion-Extension (FE) an... |
23616788 | Neuronal toxicity in HIV CNS disease. | HIV enters the brain during the early stages of initial infection and can result in a complicated array of diverse neurological dysfunctions. While neuronal injury and loss are at the heart of neurological decline and HIV-associated neuropathology, HIV does not productively infect neurons and the effects of HIV on neur... | [
[
"9467688",
"Midodrine. A review of its therapeutic use in the management of orthostatic hypotension.",
"Midodrine is a prodrug which undergoes enzymatic hydrolysis to the selective alpha 1-adrenoceptor agonist desglymidodrine after oral administration. Oral midodrine significantly increases 1-minute s... | [
[
"23197532",
"A large-scale model of the functioning brain.",
"A central challenge for cognitive and systems neuroscience is to relate the incredibly complex behavior of animals to the equally complex activity of their brains. Recently described, large-scale neural models have not bridged this gap betw... |
22328183 | Towards a closed-loop cochlear implant system: application of embedded monitoring of peripheral and central neural activity. | Although the cochlear implant (CI) is widely considered the most successful neural prosthesis, it is essentially an open-loop system that requires extensive initial fitting and frequent tuning to maintain a high, but not necessarily optimal, level of performance. Two developments in neuroscience and neuroengineering no... | [
[
"18491163",
"Population vector code: a geometric universal as actuator.",
"The population vector code relates directional tuning of single cells and global, directional motion incited by an assembly of neurons. In this paper three things are done. First, we analyze the population vector code as a pure... | [
[
"23041373",
"Developmental treatment with bisphenol A causes few alterations on measures of postweaning activity and learning.",
"Widespread bisphenol A (BPA) exposure necessitates increased knowledge of its potential effects for better risk assessment and regulatory guidance. Here, female Sprague-Daw... |
23240711 | Subjective response to alcohol among alcohol-dependent individuals: effects of the μ-opioid receptor (OPRM1) gene and alcoholism severity. | Subjective response to alcohol has been examined as a marker of alcoholism risk. The A118G single-nucleotide polymorphism (SNP) of the mu-opioid receptor (OPRM1) gene has been previously associated with subjective response to alcohol in heavy drinkers. This study seeks to extend the literature by examining the effect o... | [
[
"11807554",
"Humans integrate visual and haptic information in a statistically optimal fashion.",
"When a person looks at an object while exploring it with their hand, vision and touch both provide information for estimating the properties of the object. Vision frequently dominates the integrated visu... | [
[
"23197674",
"Surface electromyography recording of spontaneous eyeblinks: applications in neuroprosthetics.",
"We are designing an implantable neuroprosthesis for the treatment of unilateral facial paralysis. The envisioned biomimetic device paces artificial blinks in the paretic eyelid when activity ... |
22963524 | Non-genomic action of beclomethasone dipropionate on bronchoconstriction caused by leukotriene C4 in precision cut lung slices in the horse. | Glucocorticoids have been proven to be effective in the therapy of recurrent airway obstruction (RAO) in horses via systemic as well as local (inhalative) administration. Elective analysis of the effects of this drug on bronchoconstriction in viable lung tissue offers an insight into the mechanism of action of the infl... | [
[
"16959837",
"Postnatal development of kisspeptin neurons in mouse hypothalamus; sexual dimorphism and projections to gonadotropin-releasing hormone neurons.",
"The neuropeptide kisspeptin has recently been implicated as having a critical role in the activation of the GnRH neurons to bring about pubert... | [
[
"22959113",
"Neural correlates of emotion processing: from emotional to social brain.",
"Different models of emotion highlight the role of strategic brain regions in emotion identification, response and regulation. Cortical, subcortical and limbic structures constitute the emotional brain. In this sho... |
23160115 | Why share data? Lessons learned from the fMRIDC. | Neuroimaging and the discipline of cognitive neuroscience have grown together in lock-step with each pushing the other toward an improved ability to explore and examine brain function and form. However successful neuroimaging and the examination of cognitive processes may seem today, the culture of data sharing in thes... | [
[
"18491163",
"Population vector code: a geometric universal as actuator.",
"The population vector code relates directional tuning of single cells and global, directional motion incited by an assembly of neurons. In this paper three things are done. First, we analyze the population vector code as a pure... | [
[
"23001148",
"An observational study of the effectiveness and safety of growth hormone (Humatrope(®)) treatment in Japanese children with growth hormone deficiency or Turner syndrome.",
"This study assessed the effectiveness and safety of growth hormone (GH; Humatrope(®)) therapy in Japanese child... |
23542825 | Neuroanatomy of Cornudescoides kulkarnii n. sp., a gill parasite of Mystus vittatus in Meerut (UP), India. | Chemical named 5-bromo indoxyl acetate has been used to describe the nervous system of a viviparous monogenean Cornudescoides Kulkarni (1969), a gill parasite of Mystus vittatus. Central nervous system consists of paired cerebral ganglia from which anterior and posterior neuronal pathways arise. These neuronal pathways... | [
[
"8490989",
"Epidemiology of epilepsy in developing countries.",
"Epilepsy is an important health problem in developing countries, where its prevalence can be up to 57 per 1000 population. This article reviews the epidemiology of epilepsy in developing countries in terms of its incidence, prevalence, s... | [
[
"23391878",
"The dialectical law between coronary artery disease and stroke recurrence.",
"In this issue of Neuroendocrinology Letters Kováčik et al. reported that coronary artery disease is not associated with stroke recurrence. Although the data were analyzed by statistical methods and th... |
23033443 | Apraxia of speech: concepts and controversies. | This article was written as an editorial to a collection of original articles on apraxia of speech (AOS) in which some of the more recent advancements in the understanding of this syndrome are discussed. It covers controversial issues concerning the theoretical foundations of AOS. Our approach was motivated by a change... | [
[
"18565765",
"Nonlinear dynamic causal models for fMRI.",
"Models of effective connectivity characterize the influence that neuronal populations exert over each other. Additionally, some approaches, for example Dynamic Causal Modelling (DCM) and variants of Structural Equation Modelling, describe how e... | [
[
"23576843",
"Possibilities offered by implantable miniaturized cuff-electrodes for insect neurophysiology.",
"Recent advances in microsystems technology led to a miniaturization of cuff-electrodes, which suggests these electrodes not just for long-term neuronal recordings in mammalians, but also in me... |
22459075 | Brain evolution and human neuropsychology: the inferential brain hypothesis. | Collaboration between human neuropsychology and comparative neuroscience has generated invaluable contributions to our understanding of human brain evolution and function. Further cross-talk between these disciplines has the potential to continue to revolutionize these fields. Modern neuroimaging methods could be appli... | [
[
"10482383",
"MRI volume of the amygdala: a reliable method allowing separation from the hippocampal formation.",
"Studies of MRI-derived volume of the amygdala have been mostly performed on coronal sections where its boundaries with the hippocampus and the entorhinal cortex are indistinct. To date, al... | [
[
"22814704",
"Inflammation in anxiety.",
"The idea of the existence of an interaction between the immune system and the central nervous system (CNS) has prompted extensive research interest into the subject of \"Psychoneuroimmunology\" taking the field to an interesting level where new hypotheses are b... |
25164048 | Control consciousness. | Control consciousness is the awareness or experience of seeming to be in control of one's actions. One view, which I will be arguing against in the present paper, is that control consciousness is a form of sensory consciousness. In such a view, control consciousness is exhausted by sensory elements such as tactile and ... | [
[
"19400719",
"The science of neural interface systems.",
"The ultimate goal of neural interface research is to create links between the nervous system and the outside world either by stimulating or by recording from neural tissue to treat or assist people with sensory, motor, or other disabilities of n... | [
[
"21312401",
"Functional brain imaging in schizophrenia: selected results and methods.",
"Functional brain imaging studies of patients with schizophrenia may be grouped into those that assume that the signs and symptoms of schizophrenia are due to disordered circuitry within a critical brain region and... |
22284580 | Christfried Jakob's late views (1930-1949) on the psychogenetic function of the cerebral cortex and its localization: culmination of the neurophilosophical thought of a keen brain observer. | This article follows the culmination of the scientific thought of the neurobiologist Christfried Jakob (1866-1956) during the later part of his career, based on publications from 1930 to 1949, when he was between 64 and 83 years of age. Jakob emphasized the necessity of bridging philosophy to the biological sciences, n... | [
[
"12060992",
"Quantification of brain lesions using interactive automated software.",
"We developed an interactive program, Analysis of Brain Lesions (ABLe) so that researchers studying the effects of brain lesions on cognition could have a user-friendly tool that could quantitatively characterize such... | [
[
"23300784",
"Maternally administered sustained-release naltrexone in rats affects offspring neurochemistry and behaviour in adulthood.",
"Naltrexone is not recommended during pregnancy. However, sustained-release naltrexone implant use in humans has resulted in cases of inadvertent foetal exposure. He... |
23476081 | Framing Nicotine Addiction as a "Disease of the Brain": Social and Ethical Consequences. | In this article, we seek to better understand how a genomic vision of addiction may influence drug prevention and treatment. Though <i We explore the emerging view of addiction as a "disease of the brain" in open-ended interviews with 86 stakeholders from the fields of nicotine research and tobacco control. Interview d... | [
[
"17030182",
"The vagus nerve: a tonic inhibitory influence associated with inflammatory bowel disease in a murine model.",
"The recently proposed Inflammatory Reflex describes an interaction between the vagus nerve and peripheral macrophages, resulting in attenuation of proinflammatory cytokine releas... | [
[
"23275858",
"Brain state-triggered stimulus delivery: An efficient tool for probing ongoing brain activity.",
"What is the relationship between variability in ongoing brain activity <i"
]
] |
23234107 | In ADHD patients performing the Counting Stroop task: a social neuroscience approach. | Attention Deficit/Hyperactivity Disorder (ADHD) symptoms are manifested in social dynamics. In this study, the brain activity of eight child and adolescent patients diagnosed with ADHD was examined while they performed the Counting Stroop task and results were interpreted using social neuroscience premises. Brain activ... | [
[
"15975514",
"Light-mediated inhibition of protein synthesis.",
"The regulation of protein synthesis is vital for a host of cell biological processes, but investigating roles for protein synthesis have been hindered by the inability to selectively interfere with it. To inhibit protein synthesis with sp... | [
[
"23060246",
"Epidemiologic aspects of traumatic brain injury in acute combat casualties at a major military medical center: a cohort study.",
"From the ongoing military conflicts in Iraq and Afghanistan, an understanding of the neuroepidemiology of traumatic brain injury (TBI) has emerged as requisite... |
23060739 | Don'T let me do that! - models of precommitment. | Precommitment, or taking away a future choice from oneself, is a mechanism for overcoming impulsivity. Here we review recent work suggesting that precommitment can be best explained through a distributed decision-making system with multiple discounting rates. This model makes specific predictions about precommitment be... | [
[
"12951145",
"Structure and function of the vomeronasal system: an update.",
"Several developments during the past 15 years have profoundly affected our understanding of the vomeronasal system (VNS) of vertebrates. In the mid 1990s, the vomeronasal epithelium of mammals was found to contain two populat... | [
[
"24294562",
"Dorello's Canal and Gruber's Ligament: Historical Perspective.",
"Wenzel Leopold Gruber and Primo Dorello were great anatomists and researchers during the 19th and 20th centuries. Their contributions to neuroanatomy-namely the Gruber's (petrosphenoidal) ligament and Dorello's canal, respe... |
23195119 | Biological databases for behavioral neurobiology. | Databases are, at their core, abstractions of data and their intentionally derived relationships. They serve as a central organizing metaphor and repository, supporting or augmenting nearly all bioinformatics. Behavioral domains provide a unique stage for contemporary databases, as research in this area spans diverse d... | [
[
"8490989",
"Epidemiology of epilepsy in developing countries.",
"Epilepsy is an important health problem in developing countries, where its prevalence can be up to 57 per 1000 population. This article reviews the epidemiology of epilepsy in developing countries in terms of its incidence, prevalence, s... | [
[
"22959113",
"Neural correlates of emotion processing: from emotional to social brain.",
"Different models of emotion highlight the role of strategic brain regions in emotion identification, response and regulation. Cortical, subcortical and limbic structures constitute the emotional brain. In this sho... |
23264886 | Neurogenetic Impairments of Brain Reward Circuitry Links to Reward Deficiency Syndrome (RDS): Potential Nutrigenomic Induced Dopaminergic Activation. | Work from our laboratory in both in-patient and outpatient facilities utilizing the Comprehensive Analysis of Reported Drugs (CARD)(™) found a significant lack of compliance to prescribed treatment medications and a lack of abstinence from drugs of abuse during active recovery. This unpublished, ongoing research... | [
[
"8490989",
"Epidemiology of epilepsy in developing countries.",
"Epilepsy is an important health problem in developing countries, where its prevalence can be up to 57 per 1000 population. This article reviews the epidemiology of epilepsy in developing countries in terms of its incidence, prevalence, s... | [
[
"22836547",
"[How free is free will? Neuro-scientific and philosophical aspects of motivation and decision-making].",
"The question concerning the postulated freedom of will continues to occupy the neuro-sciences, psychiatry, law and neuro-philosophy. Do current research results really show that freed... |
23366491 | A framework for relating neural activity to freely moving behavior. | Two research communities, motor systems neuroscience and motor prosthetics, examine the relationship between neural activity in the motor cortex and movement. The former community aims to understand how the brain controls and generates movement; the latter community focuses on how to decode neural activity as control s... | [
[
"9626715",
"The role of defeat and entrapment (arrested flight) in depression: an exploration of an evolutionary view.",
"The social rank theory of psychopathology suggests that with the evolution of social hierarchies various psychobiological mechanisms became attuned to the success or failure in con... | [
[
"23226123",
"Identifying temporal and causal contributions of neural processes underlying the Implicit Association Test (IAT).",
"The Implicit Association Test (IAT) is a popular behavioral measure that assesses the associative strength between outgroup members and stereotypical and counterstereotypic... |
21861199 | Optimal experimental design for sampling voltage on dendritic trees in the low-SNR regime. | Due to the limitations of current voltage sensing techniques, optimal filtering of noisy, undersampled voltage signals on dendritic trees is a key problem in computational cellular neuroscience. These limitations lead to voltage data that is incomplete (in the sense of only capturing a small portion of the full spatiot... | [
[
"9467688",
"Midodrine. A review of its therapeutic use in the management of orthostatic hypotension.",
"Midodrine is a prodrug which undergoes enzymatic hydrolysis to the selective alpha 1-adrenoceptor agonist desglymidodrine after oral administration. Oral midodrine significantly increases 1-minute s... | [
[
"23286166",
"Group-wise consistent fiber clustering based on multimodal connectional and functional profiles.",
"Fiber clustering is an essential step towards brain connectivity modeling and tract-based analysis of white matter integrity via diffusion tensor imaging (DTI) in many clinical neuroscience... |
23151390 | Neural responses to threat and reward interact to predict stress-related problem drinking: A novel protective role of the amygdala. | Research into neural mechanisms of drug abuse risk has focused on the role of dysfunction in neural circuits for reward. In contrast, few studies have examined the role of dysfunction in neural circuits of threat in mediating drug abuse risk. Although typically regarded as a risk factor for mood and anxiety disorders, ... | [
[
"8034358",
"Parameters of immunological competence in subjects with high consumption of fish contaminated with persistent organochlorine compounds.",
"Consumption of fatty fish species, like salmon and herring, from the Baltic Sea is an important source of human exposure to persistent organochlorine c... | [
[
"22937517",
"Optogenetics: a novel optical manipulation tool for medical investigation.",
"Optogenetics is a new and rapidly evolving gene and neuroengineering technology that allows optical control of specific populations of neurons without affecting other neurons in the brain at high temporal and sp... |
23220430 | Prospective active marker motion correction improves statistical power in BOLD fMRI. | Group level statistical maps of blood oxygenation level dependent (BOLD) signals acquired using functional magnetic resonance imaging (fMRI) have become a basic measurement for much of systems, cognitive and social neuroscience. A challenge in making inferences from these statistical maps is the noise and potential con... | [
[
"19005051",
"Light-induced rescue of breathing after spinal cord injury.",
"Paralysis is a major consequence of spinal cord injury (SCI). After cervical SCI, respiratory deficits can result through interruption of descending presynaptic inputs to respiratory motor neurons in the spinal cord. Expressio... | [
[
"21620983",
"Computational neuroergonomics.",
"Neuroergonomics merges neuroscience and ergonomics for the study of brain and behavior in natural and naturalistic settings. Together with the rapid development of neuroergonomics concepts, technologies, and related data, there is an urgent need to develo... |
22200137 | Transcranial magnetic stimulation, deep brain stimulation and personal identity: ethical questions, and neuroethical approaches for medical practice. | Neurotechnology provides means to engage micro- and macrostructural networks of the brain to both mitigate the manifestations of several neurological and psychiatric disorders, and alter cognition and motoric activity. Such capacity also generates questions of how these interventions may affect personal identity. This ... | [
[
"19400719",
"The science of neural interface systems.",
"The ultimate goal of neural interface research is to create links between the nervous system and the outside world either by stimulating or by recording from neural tissue to treat or assist people with sensory, motor, or other disabilities of n... | [
[
"21731699",
"Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain.",
"Recent discovery of 5-hydroxymethylcytosine (5hmC) in genomic DNA raises the question how this sixth base is recognized by cellular proteins. In contrast to the methyl-CpG binding domain (MBD) of MeCP2, we found that the S... |
23029114 | Monitoring performance degradation of cerebellar functions using computational neuroscience methods: implications on neurological diseases. | Neurodegeneration is a major cause of human disease. Within the cerebellum, neuronal degeneration and/or dysfunction has been associated with many diseases, including several forms of cerebellar ataxia, since normal cerebellar function is paramount for proper motor coordination, balance, and motor learning. The cerebel... | [
[
"11488376",
"Fears, phobias, and preparedness: toward an evolved module of fear and fear learning.",
"An evolved module for fear elicitation and fear learning with 4 characteristics is proposed. (a) The fear module is preferentially activated in aversive contexts by stimuli that are fear relevant in a... | [
[
"23341313",
"Absence of verbal recall or memory for symptom acquisition in fear and trauma exposure: a conceptual case for fear conditioning and learned nonuse in assessment and treatment.",
"Absence of memory or verbal recall for symptom acquisition in fear and trauma exposure, as well as absence of ... |
23124810 | Cognitive mapping in humans and its relationship to other orientation skills. | Human orientation in novel and familiar environments is a complex skill that can involve numerous different strategies. To date, a comprehensive account of how these strategies interrelate at the behavioural level has not been documented, impeding the development of elaborate systems neuroscience models of spatial orie... | [
[
"11330208",
"Microdialysis perfusion of orexin-A in the basal forebrain increases wakefulness in freely behaving rats.",
"Recent work indicates that the orexin/hypocretin-containing neurons of the lateral hypothalamus are involved in control of REM sleep phenomena, but site-specific actions in control... | [
[
"23276394",
"Biological mechanisms associated with increased perseveration and hyperactivity in a genetic mouse model of neurodevelopmental disorder.",
"Chromosomal deletions at Xp22.3 appear to influence vulnerability to the neurodevelopmental disorders attention deficit hyperactivity disorder (ADHD)... |
23367102 | Music and emotion: an EEG connectivity study in patients with disorders of consciousness. | Human emotion perception is a topic of great interest for both cognitive and clinical neuroscience, but its electrophysiological correlates are still poorly understood. The present study is aimed at evaluating if measures of synchronization and indexes based on graph-theory are a tool suitable to study and quantify ele... | [
[
"18457512",
"Timing, storage, and comparison of stimulus duration engage discrete anatomical components of a perceptual timing network.",
"The temporal discrimination paradigm requires subjects to compare the duration of a probe stimulus to that of a sample previously stored in working or long-term me... | [
[
"23316177",
"Affective neuronal selection: the nature of the primordial emotion systems.",
"Based on studies in affective neuroscience and evolutionary psychiatry, a tentative new proposal is made here as to the nature and identification of primordial emotional systems. Our model stresses phylogenetic... |
23123788 | Sensitivity to posed and genuine displays of happiness and sadness: a fMRI study. | The ability to distinguish posed from genuine facial displays of emotion and to act accordingly is a fundamental social skill. To investigate the neural correlates underpinning this sensitivity, we compared changes in brain activity associated with judging posed and genuine facial displays of happiness and sadness usin... | [
[
"15659602",
"Ensemble coding of vocal control in birdsong.",
"Zebra finch song is represented in the high-level motor control nucleus high vocal center (HVC) (Reiner et al., 2004) as a sparse sequence of spike bursts. In contrast, the vocal organ is driven continuously by smoothly varying muscle contr... | [
[
"23316137",
"Real-time system for studies of the effects of acoustic feedback on animal vocalizations.",
"Studies of behavioral and neural responses to distorted auditory feedback (DAF) can help shed light on the neural mechanisms of animal vocalizations. We describe an apparatus for generating real-t... |
22287251 | Towards a healthy human model of neural disorders of movement. | A quantitative approach to virtual-lesion physiology is presented which integrates event-related fMRI, image-guided, repetitive, transcranial magnetic stimulation (irTMS), and simultaneous recording of 3-D movement kinematics. By linking motor neuroscience with clinical disorders of motor function, our method allows de... | [
[
"15525757",
"Identification of amino acid residues in the insect sodium channel critical for pyrethroid binding.",
"The voltage-gated sodium channel is the primary target site of pyrethroids, which constitute a major class of insecticides used worldwide. Pyrethroids prolong the opening of sodium chann... | [
[
"23055482",
"Towards a new neurobiology of language.",
"Theoretical advances in language research and the availability of increasingly high-resolution experimental techniques in the cognitive neurosciences are profoundly changing how we investigate and conceive of the neural basis of speech and langua... |
23022590 | Fruit fly behavior in response to chemosensory signals. | An important question in contemporary sensory neuroscience is how animals perceive their environment and make appropriate behavioral choices based on chemical perceptions. The fruit fly Drosophila melanogaster exhibits robust tastant and odor-evoked behaviors. Understanding how the gustatory and olfactory systems suppo... | [
[
"22240730",
"Birdsong neurolinguistics: songbird context-free grammar claim is premature.",
"There are remarkable behavioral, neural, and genetic similarities between song learning in songbirds and speech acquisition in human infants. Previously, we have argued that this parallel cannot be extended to... | [
[
"23062307",
"Childhood adversity and DNA methylation of genes involved in the hypothalamus-pituitary-adrenal axis and immune system: whole-genome and candidate-gene associations.",
"In recent years, translational research involving humans and animals has uncovered biological and physiological pathways... |
22942879 | A current review of cypermethrin-induced neurotoxicity and nigrostriatal dopaminergic neurodegeneration. | Cypermethrin, a class II pyrethroid pesticide, is used to control insects in the household and agricultural fields. Despite beneficial roles, its uncontrolled and repetitive applications lead to unintended effects in non-target organisms. Cypermethrin crosses the blood-brain barrier and induces neurotoxicity and motor ... | [
[
"9222381",
"Molecular mimicry between HIV-1 gp41 and an astrocyte isoform of alpha-actinin.",
"A 100-kDa astrocyte antigen previously shown to cross-react with a monoclonal antibody (MAb) generated against amino acids (aa) 598 to 609 of the transmembrane protein gp41 of human immunodeficiency virus ty... | [
[
"23469524",
"[Analysis of characteristics of alpha electroencephalogram during the interaction between emotion and cognition based on Granger causality].",
"Studying the functional network during the interaction between emotion and cognition is an important way to reveal the underlying neural connecti... |
23316137 | Real-time system for studies of the effects of acoustic feedback on animal vocalizations. | Studies of behavioral and neural responses to distorted auditory feedback (DAF) can help shed light on the neural mechanisms of animal vocalizations. We describe an apparatus for generating real-time acoustic feedback. The system can very rapidly detect acoustic features in a song and output acoustic signals if the det... | [
[
"16959837",
"Postnatal development of kisspeptin neurons in mouse hypothalamus; sexual dimorphism and projections to gonadotropin-releasing hormone neurons.",
"The neuropeptide kisspeptin has recently been implicated as having a critical role in the activation of the GnRH neurons to bring about pubert... | [
[
"23293624",
"Cross-linguistic differences in the neural representation of human language: evidence from users of signed languages.",
"Studies of deaf individuals who are users of signed languages have provided profound insight into the neural representation of human language. Case studies of deaf sign... |
20181553 | Organization and physiology of posterior lateral line afferent neurons in larval zebrafish. | The lateral line system of larval zebrafish can translate hydrodynamic signals from the environment to guide body movements. Here, I demonstrate a spatial relationship between the organization of afferent neurons in the lateral line ganglion and the innervation of neuromasts along the body. I developed a whole cell pat... | [
[
"17940025",
"Short-term meditation training improves attention and self-regulation.",
"Recent studies suggest that months to years of intensive and systematic meditation training can improve attention. However, the lengthy training required has made it difficult to use random assignment of participant... | [
[
"23853342",
"HermesD: A High-Rate Long-Range Wireless Transmission System for Simultaneous Multichannel Neural Recording Applications.",
"HermesD is a high-rate, low-power wireless transmission system to aid research in neural prosthetic systems for motor disabilities and basic motor neuroscience. It ... |
23054668 | The ethics of neuroscience and the neuroscience of ethics: a phenomenological-existential approach. | Advances in the neurosciences have many implications for a collective understanding of what it means to be human, in particular, notions of the self, the concept of volition or agency, questions of individual responsibility, and the phenomenology of consciousness. As the ability to peer directly into the brain is scien... | [
[
"486593",
"A mathematical theory of visual hallucination patterns.",
"Neuronal activity in a two-dimensional net is analyzed in the neighborhood of an instability. Bifurcation theory and group theory are used to demonstrate the existence of a variety of doubly-periodic patterns, hexagons, rolls, etc.,... | [
[
"22492047",
"Encoding of sensory prediction errors in the human cerebellum.",
"A central tenet of motor neuroscience is that the cerebellum learns from sensory prediction errors. Surprisingly, neuroimaging studies have not revealed definitive signatures of error processing in the cerebellum. Furthermo... |
22307590 | Functional profiling of neurons through cellular neuropharmacology. | We describe a functional profiling strategy to identify and characterize subtypes of neurons present in a peripheral ganglion, which should be extendable to neurons in the CNS. In this study, dissociated dorsal-root ganglion neurons from mice were exposed to various pharmacological agents (challenge compounds), while a... | [
[
"22264561",
"Exome sequencing identifies KIAA1377 and C5orf42 as susceptibility genes for monomelic amyotrophy.",
"Precise topographic localization, predominance in males mostly of Asian origin, and existence of some familial cases suggest a genetic background for monomelic amyotrophy. To identify sus... | [
[
"23245548",
"Family history: a guide for neurologists in the age of genomic medicine.",
"The field of neurogenetics has expanded dramatically over recent years. Neurogenetics has developed from a distinct subspecialty within neurology to something that transcends most of the common presenting conditio... |
22654752 | PyXNAT: XNAT in Python. | As neuroimaging databases grow in size and complexity, the time researchers spend investigating and managing the data increases to the expense of data analysis. As a result, investigators rely more and more heavily on scripting using high-level languages to automate data management and processing tasks. For this, a str... | [
[
"9337589",
"Rate of temporal discounting decreases with amount of reward.",
"The present, subjective value of a delayed reward is a decreasing function of the duration of the delay. This phenomenon is termed temporal discounting. To determine whether the amount of the reward influences the rate of tem... | [
[
"23214292",
"Neuroprostheses for increasing disabled patients' mobility and control.",
"Neuroprostheses are electronic devices using electrophysiological signals to stimulate muscles, electronic/ mechanical devices such as substitutes for limbs or parts of limbs, or computers. The development of neuro... |
20700045 | Comparative neuroscience of stimulant-induced memory dysfunction: role for neurogenesis in the adult hippocampus. | The discovery that the addictive drugs impair neurogenesis in the adult hippocampus has prompted the elaboration of new biological hypotheses to explain addiction and drug-induced cognitive dysfunction. Considerable evidence now implicates the process of adult neurogenesis in at least some critical components of hippoc... | [
[
"18927384",
"Optical switches for remote and noninvasive control of cell signaling.",
"Although the identity and interactions of signaling proteins have been studied in great detail, the complexity of signaling networks cannot be fully understood without elucidating the timing and location of activity... | [
[
"20530254",
"Sensitivity and selectivity of neurons in auditory cortex to the pitch, timbre, and location of sounds.",
"We are able to rapidly recognize and localize the many sounds in our environment. We can describe any of these sounds in terms of various independent \"features\" such as their loudn... |
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