Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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cell migration face morphogenesis leukocyte differentiation negative regulation of Schwann cell migration positive regulation of angiogenesis positive regulation of endothelial cell migration positive regulation of endothelial cell-matrix adhesion via fibronectin positive regulation of vasculogenesis regulation of ERK1... | plasma membrane | GDP binding GTP binding GTPase activity protein-containing complex binding | Rattus norvegicus | Cell membrane GTP-binding Hydrolase Lipoprotein Membrane Methylation Nucleotide-binding Palmitate Prenylation Reference proteome | MSSGAASGTG | MSSGAASGTGRGRPRGGGPGPRDPPPGETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICTVDGIPARLDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFIEVSKLFTQILRVKDRDDFPIVLVGNKADLETQRQVLRSEASSFSASHHMTYFEASAKLRLNVDEAFEQLVRTVRKYQEQELPPSPPSAPRKKDGRCPCVLL | cell migration face morphogenesis leukocyte differentiation negative regulation of Schwann cell migration positive regulation of angiogenesis positive regulation of endothelial cell migration positive regulation of endothelial cell-matrix adhesion via fibronectin positive regulation of vasculogenesis regulation of ERK1... |
chromatin remodeling chromosome separation DNA double-strand break processing regulation of DNA recombination | heterochromatin; nuclear replication fork; nucleoplasm; nucleus; site of double-strand break | ATP binding ATP hydrolysis activity ATP-dependent activity, acting on DNA ATP-dependent chromatin remodeler activity chromatin binding DNA binding helicase activity ubiquitin binding | Rattus norvegicus | Acetylation ATP-binding Chromatin regulator Chromosome DNA damage DNA repair DNA-binding Helicase Hydrolase Isopeptide bond Nucleotide-binding Nucleus Phosphoprotein Reference proteome Repeat Ubl conjugation | MNLFNLDRFR | MNLFNLDRFRFEKRSKIEEAPEAAPQPSQPGPSSPISLSAEEENAEGEVSRANTPDSDVTEKTEDSSVPEPPDNESKASLSCFQNQRTIQEYIDLSSDSEDVSPNCSSTVQEKKFSKDTVIIVSEPSEDEESHDLPSATRRNDISELEDLSELEDLKDAKLQTLKELFPQRSDSDLLKLIDSTSTMDGAIAAALLKFGDAGGGPRKRKLSSSSEAYEEDEANDDQSLKKPRGDRREESNESAEASSNWEKQESIVLKLQKEFPNFDKQELREVLKEHEWMYTEALESLKVFAEDQDVQCASQSEVTNGKEVARNQNYSKN... | chromatin remodeling chromosome separation DNA double-strand break processing regulation of DNA recombination heterochromatin; nuclear replication fork; nucleoplasm; nucleus; site of double-strand break ATP binding ATP hydrolysis activity ATP-dependent activity, acting on DNA ATP-dependent chromatin remodeler activity ... |
excitatory postsynaptic potential long-term synaptic potentiation maintenance of postsynaptic density structure postsynapse organization protein homooligomerization | cell-cell junction; cytoplasm; cytoskeleton; dendrite membrane; dendritic shaft; dendritic spine; glutamatergic synapse; plasma membrane; postsynaptic density; postsynaptic density membrane; Schaffer collateral - CA1 synapse | PDZ domain binding structural constituent of postsynaptic density transmembrane transporter binding | Rattus norvegicus | Cell projection Cytoplasm Cytoskeleton Membrane Phosphoprotein Reference proteome SH3 domain Synapse | MPVAATNSES | MPVAATNSESAMQQVLDNLGSLPNATGAAELDLIFLRGIMESPIVRSLAKAHERLEETKLEAVRDNNLELVQEILRDLAELAEQSSTAAELARILQEPHFQSLLETHDSVASKTYETPPPSPGLDPTFSNQPVPPDAVRMVGIRKTAGEHLGVTFRVEGGELVIARILHGGMVAQQGLLHVGDIIKEVNGQPVGSDPRALQELLRSASGSVILKILPSYQEPHLPRQVFVKCHFDYDPARDSLIPCKEAGLRFNAGDLLQIVNQDDANWWQACHVEGGSAGLIPSQLLEEKRKAFVKRDLELTPTSGTLCGSLSGKKKKR... | excitatory postsynaptic potential long-term synaptic potentiation maintenance of postsynaptic density structure postsynapse organization protein homooligomerization cell-cell junction; cytoplasm; cytoskeleton; dendrite membrane; dendritic shaft; dendritic spine; glutamatergic synapse; plasma membrane; postsynaptic dens... |
amyloid precursor protein metabolic process cellular response to cytokine stimulus cholesterol homeostasis cholesterol metabolic process low-density lipoprotein particle clearance positive regulation of low-density lipoprotein particle clearance positive regulation of receptor-mediated endocytosis positive regulation o... | axon; basal plasma membrane; cytoplasm; cytoplasmic side of plasma membrane; cytosol; early endosome; neurofilament; recycling endosome | amyloid-beta binding AP-1 adaptor complex binding AP-2 adaptor complex binding clathrin adaptor activity clathrin binding low-density lipoprotein particle receptor binding phosphatidylinositol-4,5-bisphosphate binding phosphotyrosine residue binding signaling adaptor activity signaling receptor complex adaptor activity... | Rattus norvegicus | 3D-structure Acetylation Cholesterol metabolism Cytoplasm Endocytosis Lipid metabolism Phosphoprotein Reference proteome Steroid metabolism Sterol metabolism | MDALKSAGRA | MDALKSAGRALIRSPSLAKQSWAGGRHRKLPENWTDTRETLLEGMVFSLKYLGMTLVERPKGEELSAAAVKRIVATAKASGKKLQKVTLKVSPRGIILTDSLTSQLIENVSIYRISYCTAQMHDKVFAYIAQSQQNESLECHAFLCTKRKVAQAVTLTVAQAFKVAFEFWQVSKEEKEKREKANQEGGDVPGTRRDSTPSLKTSVATGNLLDLEELAKAPLSTVSANTKNMDDALRPQVLGNNSVVWELDDGLDEAFSRLAQSRTNPQVLDTGLTAQDIHYAQCLSPTDWDKPDSSGFDQDDVFSF | amyloid precursor protein metabolic process cellular response to cytokine stimulus cholesterol homeostasis cholesterol metabolic process low-density lipoprotein particle clearance positive regulation of low-density lipoprotein particle clearance positive regulation of receptor-mediated endocytosis positive regulation o... |
lipid droplet formation mitochondrial protein catabolic process phosphatidylethanolamine biosynthetic process protein autoprocessing regulation of mitochondrion organization | lipid droplet; mitochondrial inner membrane; mitochondrion | phosphatidylserine decarboxylase activity | Rattus norvegicus | Cytoplasm Decarboxylase Lipid biosynthesis Lipid droplet Lipid metabolism Lyase Membrane Mitochondrion Mitochondrion inner membrane Phospholipid biosynthesis Phospholipid metabolism Pyruvate Reference proteome Transit peptide Transmembrane Transmembrane helix Zymogen | MAVAGGRGCV | MAVAGGRGCVRSLREGVLWRSSPCHCDYTATRHFLGALQKLPLQAWVRKVHTAPLRTLFLLRPVPILLAAGGGYAGYRQYEKYRERQLEKLGLEIPPKLASHWEVSLYKSVPTRLLSRACGRLNQVELPSWLRRPVYSLYIWTFGVNMTEAAVEDLQHYRNLSEFFRRKLKPQARPVCGLHSVISPSDGKILTFGQVKNSEVEQVKGVTYSLESFLGPRACTEDLPFPPASSCDSFRNQLVTREGNELYHCVIYLAPGDYHCFHSPTDWTVSHRRHFPGSLMSVNPGMARWIKELFCHNERVVLTGDWKHGFFSLTAVGA... | lipid droplet formation mitochondrial protein catabolic process phosphatidylethanolamine biosynthetic process protein autoprocessing regulation of mitochondrion organization lipid droplet; mitochondrial inner membrane; mitochondrion phosphatidylserine decarboxylase activity Rattus norvegicus Cytoplasm Decarboxylase Lip... |
endothelin receptor signaling pathway epidermal growth factor receptor signaling pathway insulin receptor signaling pathway lens morphogenesis in camera-type eye positive regulation of cell population proliferation positive regulation of GTPase activity positive regulation of MAPK cascade positive regulation of peptidy... | cytoplasm; focal adhesion; membrane | guanyl-nucleotide exchange factor activity kinase binding phosphotyrosine residue binding | Rattus norvegicus | Acetylation Cell junction Cytoplasm Guanine-nucleotide releasing factor Methylation Phosphoprotein Reference proteome SH2 domain | MAAGKFASLP | MAAGKFASLPRHMPVNHQFPLASSMDLLSSKSPLAEHRTEAYPDVSIHGTLPRKKKGPPPIRSCDSASHMGTLPHSKSPRQSSPLTQDLILEKPLPDWKGDSFAFRDPYLLDPTLEYVKFSKERHIMDRTPERLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPINRTVPLWCLEERYGTSPGRGREGSFAEGRPDVVKRLSLTTGGIQARDHSLPRGNLLRNKDKSGSQPA... | endothelin receptor signaling pathway epidermal growth factor receptor signaling pathway insulin receptor signaling pathway lens morphogenesis in camera-type eye positive regulation of cell population proliferation positive regulation of GTPase activity positive regulation of MAPK cascade positive regulation of peptidy... |
cellular response to potassium ion positive regulation of NLRP3 inflammasome complex assembly positive regulation of telomere capping positive regulation of telomere maintenance via telomerase protein phosphorylation regulation of mitotic cell cycle | centrosome; cytoplasm; microtubule organizing center; nucleus; spindle pole | ATP binding metal ion binding molecular function activator activity protein serine kinase activity protein serine/threonine kinase activity | Rattus norvegicus | Acetylation ATP-binding Cytoplasm Cytoskeleton Kinase Magnesium Metal-binding Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MDEQPQGMQG | MDEQPQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDIAYVYDVAKRMHACTASS | cellular response to potassium ion positive regulation of NLRP3 inflammasome complex assembly positive regulation of telomere capping positive regulation of telomere maintenance via telomerase protein phosphorylation regulation of mitotic cell cycle centrosome; cytoplasm; microtubule organizing center; nucleus; spindle... |
chromatin organization chromosome condensation establishment of protein localization to chromatin muscle organ development negative regulation of DNA recombination negative regulation of transcription by RNA polymerase II nucleosome assembly protein stabilization | chromatin; heterochromatin; nucleosome; nucleus | chromatin DNA binding DNA binding double-stranded DNA binding histone deacetylase binding nucleosomal DNA binding structural constituent of chromatin | Rattus norvegicus | Acetylation Chromosome Citrullination DNA-binding Hydroxylation Methylation Nucleus Phosphoprotein Reference proteome | MSETAPAETT | MSETAPAETTAPAPVEKSPAKKKTKKAGAAKRKATGPPVSELITKAVSASKERGGVSLPALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKVASGEAKPKAKKTGAAKAKKPTGATPKKPKKTAGAKKTVKKTPKKAKKPAAAGVKKVTKSPKKAKAAAKPKKATKSPARPKAVKSKASKPKVTKPKAAKPKAAKVKKAVSKKK | chromatin organization chromosome condensation establishment of protein localization to chromatin muscle organ development negative regulation of DNA recombination negative regulation of transcription by RNA polymerase II nucleosome assembly protein stabilization chromatin; heterochromatin; nucleosome; nucleus chromati... |
cellular response to high density lipoprotein particle stimulus cellular response to leukemia inhibitory factor cholesterol efflux cholesterol homeostasis positive regulation of cholesterol biosynthetic process positive regulation of cholesterol efflux regulation of DNA-templated transcription sterol transport transmem... | cytoplasmic vesicle; endosome; endosome membrane; plasma membrane | ABC-type sterol transporter activity ATP binding ATP hydrolysis activity identical protein binding protein heterodimerization activity protein homodimerization activity | Rattus norvegicus | ATP-binding Cell membrane Cytoplasmic vesicle Endosome Membrane Nucleotide-binding Reference proteome Translocase Transmembrane Transmembrane helix Transport | MAEKALEAVG | MAEKALEAVGCGLGPGAVAMAVALEDGAEPPVLTTHLKKVENHITEAQRFSHLPKRSAVDIEFVELSYSVREGPCWRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILAGYRESGMKGQILVNGRPRDLRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEKQEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKSLAHGGRTVICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPADFIIEVASGEYGDL... | cellular response to high density lipoprotein particle stimulus cellular response to leukemia inhibitory factor cholesterol efflux cholesterol homeostasis positive regulation of cholesterol biosynthetic process positive regulation of cholesterol efflux regulation of DNA-templated transcription sterol transport transmem... |
cholesterol homeostasis negative regulation of low-density lipoprotein particle clearance negative regulation of neuron projection development nervous system development positive regulation of protein catabolic process protein destabilization protein ubiquitination regulation of low-density lipoprotein particle recepto... | cytoplasm; cytoskeleton; plasma membrane | cytoskeletal protein binding metal ion binding ubiquitin protein ligase activity ubiquitin-protein transferase activity | Rattus norvegicus | Cell membrane Cytoplasm Iron Membrane Metal-binding Reference proteome Transferase Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger | MLCYVTRPDA | MLCYVTRPDAVLMEVEVEAKANGEDCLNQVCRRLGIIEVDYFGLQFTGSKGESLWLNLRNRISQQMDGLAPYRLKLRVKFFVEPHLILQEQTRHIFFLHIKESLLAGHLQCSPEQAVELSALLAQTKFGDYNQNTAQYSYEDLCEKELSSSTLNSIVGKHKELEGISQASAEYQVLQIVSAMENYGIEWHAVRDSEGQKLLIGVGPEGISICKEDFSPINRIAYPVVQMATQSGKNVYLTVTKESGNSIVLLFKMISTRAASGLYRAITETHAFYRCDTVTSAVMMQYSRDLKGHLASLFLNENINLGKKYVFDIKRTSK... | cholesterol homeostasis negative regulation of low-density lipoprotein particle clearance negative regulation of neuron projection development nervous system development positive regulation of protein catabolic process protein destabilization protein ubiquitination regulation of low-density lipoprotein particle recepto... |
negative regulation of TORC1 signaling positive regulation of protein polyubiquitination positive regulation of protein ubiquitination proteasome-mediated ubiquitin-dependent protein catabolic process protein K48-linked ubiquitination protein polyubiquitination ubiquitin-dependent protein catabolic process | cytoplasm; nucleus; protein-containing complex; ubiquitin ligase complex | ATP binding ubiquitin conjugating enzyme activity ubiquitin protein ligase activity ubiquitin protein ligase binding ubiquitin-protein transferase activity | Rattus norvegicus | ATP-binding Cytoplasm Nucleotide-binding Reference proteome Transferase Ubl conjugation Ubl conjugation pathway | MALKRIQKEL | MALKRIQKELSDLQRDPPAHCSAGPVGDDLFHWQATIMGPPDSAYQGGVFFLTVHFPTDYPFKPPKIAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLVPDIAQIYKSDKEKYNRHAREWTQKYAM | negative regulation of TORC1 signaling positive regulation of protein polyubiquitination positive regulation of protein ubiquitination proteasome-mediated ubiquitin-dependent protein catabolic process protein K48-linked ubiquitination protein polyubiquitination ubiquitin-dependent protein catabolic process cytoplasm; n... |
glycerol biosynthetic process glycerophospholipid metabolic process negative regulation of gluconeogenesis | cytoplasm; cytosol | ADP phosphatase activity glycerol-1-phosphatase activity glycerol-3-phosphatase activity magnesium ion binding phosphoglycolate phosphatase activity protein tyrosine phosphatase activity | Rattus norvegicus | Carbohydrate metabolism Hydrolase Magnesium Metal-binding Protein phosphatase Reference proteome | MAEAEAGGDE | MAEAEAGGDEVRCVRLSAERAKLLLAEVDTLLFDCDGVLWRGETAVPGAPETLRALRARGKRLGFITNNSSKTRTAYAEKLRRLGFGGPMGPEAGLEVFGTAYCSALYLRQRLAGVPDPKAYVLGSPALAAELEAVGVTSVGVGPDVLHGDGPSDWLAVPLEPDVRAVVVGFDPHFSYMKLTKAVRYLQQPDCLLVGTNMDNRLPLENGRFIAGTGCLVRAVEMAAQRQADIIGKPSRFIFDCVSQEYGINPERTVMVGDRLDTDILLGSTCSLKTILTLTGVSSLEDVKSNQESDCMFKKKMVPDFYVDSIADLLPALQ... | glycerol biosynthetic process glycerophospholipid metabolic process negative regulation of gluconeogenesis cytoplasm; cytosol ADP phosphatase activity glycerol-1-phosphatase activity glycerol-3-phosphatase activity magnesium ion binding phosphoglycolate phosphatase activity protein tyrosine phosphatase activity Rattus ... |
cell morphogenesis glucose homeostasis regulation of insulin secretion involved in cellular response to glucose stimulus response to glucose RNA catabolic process RNA transport type B pancreatic cell development type B pancreatic cell proliferation | lysosomal membrane; lysosome; plasma membrane | AP-1 adaptor complex binding AP-2 adaptor complex binding DNA binding double-stranded RNA binding nucleic acid transmembrane transporter activity RNA transmembrane transporter activity | Rattus norvegicus | Cell membrane DNA-binding Glycoprotein Lysosome Membrane Phosphoprotein Reference proteome RNA-binding Signal Transmembrane Transmembrane helix Transport | MIAWRLPLCV | MIAWRLPLCVLLVAAVESHLGALGPKNVSQKDAEFERTYADDVNSELVNIYTFNHTVTRNRTEGVRVSVNVLNKQKGAPLLFVVRQKEAVVSFQVPLILRGLYQRKYLYQKVERTLCQPPTKNESEIQFFYVDVSTLSPVNTTYQLRVNRVDNFVLRTGELFTFNTTAAQPQYFKYEFPDGVDSVIVKVTSKKAFPCSVISIQDVLCPVYDLDNNVAFIGMYQTMTKKAAITVQRKDFPSNSFYVVVVVKTEDQACGGSLPFYPFVEDEPVDQGHRQKTLSVLVSQAVTSEAYVGGMLFCLGIFLSFYLLTVLLACWENW... | cell morphogenesis glucose homeostasis regulation of insulin secretion involved in cellular response to glucose stimulus response to glucose RNA catabolic process RNA transport type B pancreatic cell development type B pancreatic cell proliferation lysosomal membrane; lysosome; plasma membrane AP-1 adaptor complex bind... |
actin cytoskeleton organization actin filament polymerization bicellular tight junction assembly endocytic recycling neuron projection development substrate adhesion-dependent cell spreading | actin filament bundle; bicellular tight junction; cell-cell junction; cytosol; neuron projection; plasma membrane; recycling endosome | actin filament binding actinin binding filamin binding metal ion binding small GTPase binding | Rattus norvegicus | Cell junction Cell membrane Cell projection Coiled coil Cytoplasm Cytoskeleton Endosome LIM domain Membrane Metal-binding Phosphoprotein Reference proteome Tight junction Zinc | MAAIKALQEW | MAAIKALQEWCRQQCEGYRDVSITNMTTSFRDGLAFCAILHRHRPDLINFNALRKENIYENNKLAFQVAEEQLGIPALLDAEDMVALKIPDRLSILTYVSQYYNYFHGRSPIGGMAGMKRPSSDSTEELSGKKKVPSQPAKLSSPVPTQRLPLSPARTNPVVQRNEGVSERPSPKAAPGTVGSSVSSICGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSSTLHSGAYRATGEPGVFVCTHHSSEAVSVSPKLSNLASRQPGGGIADTRPIGVSQKVLETNGEATPLRARTAAWEHAGGNRAAKGFVQTELTPPATSRVH... | actin cytoskeleton organization actin filament polymerization bicellular tight junction assembly endocytic recycling neuron projection development substrate adhesion-dependent cell spreading actin filament bundle; bicellular tight junction; cell-cell junction; cytosol; neuron projection; plasma membrane; recycling endo... |
cell maturation cytoskeleton organization intermediate filament cytoskeleton organization intermediate filament organization lens fiber cell development response to stimulus visual perception | cell cortex; cytoplasm; cytoskeleton; intermediate filament; plasma membrane | structural constituent of eye lens | Rattus norvegicus | Acetylation Cell membrane Coiled coil Cytoplasm Cytoskeleton Eye lens protein Intermediate filament Membrane Phosphoprotein Reference proteome Sensory transduction Vision | MSERRVAMDL | MSERRVAMDLPSGSNASMPLQRHRVSSLRGTRSPSSLDSPPASRTSAVGSLVRAPGVYVGVAPSGGIGGLGARVTRRALGISSVFLQGLRSSGLATAPAPGPERNHATAEDLGGCLVEYMTKVHALEQVSQELETQLRAHLESKAKRSGGWDALRASWASSYQQVGEAVLENARLMLQMETIQAGADDFKERYENEQPFRKAAEEEVSSLYKVIDEANLTKTDLEHQIESLKEELGSLSRSYEEDVKVLYKQLAGSELEQTDVPMGTGLDDVLETIRVQWERDVEKNRAEAGAVLQAKQQTEVVHVSQTQEEKLAAALSV... | cell maturation cytoskeleton organization intermediate filament cytoskeleton organization intermediate filament organization lens fiber cell development response to stimulus visual perception cell cortex; cytoplasm; cytoskeleton; intermediate filament; plasma membrane structural constituent of eye lens Rattus norvegicu... |
cAMP-mediated signaling diacylglycerol metabolic process G protein-coupled receptor signaling pathway glycerolipid metabolic process intracellular signal transduction lipid phosphorylation negative regulation of gene expression negative regulation of peptidyl-threonine phosphorylation phosphatidic acid biosynthetic pro... | cytoplasm; cytoskeleton; cytosol; endosome; glutamatergic synapse; nuclear matrix; nuclear speck; nucleolus; nucleus; plasma membrane; postsynapse; presynapse; vesicle membrane | ATP binding ATP-dependent diacylglycerol kinase activity DNA-binding transcription factor binding kinase binding metal ion binding phospholipase binding transmembrane receptor protein tyrosine kinase activator activity | Rattus norvegicus | ATP-binding Cell membrane Cytoplasm Cytoskeleton Kinase Lipid metabolism Membrane Metal-binding Nucleotide-binding Nucleus Phosphoprotein Reference proteome Repeat Synapse Transferase Zinc Zinc-finger | MATAAESGAR | MATAAESGARTWPGSGSPRLGSPAGSPVLGISGRARPGSGPERTGRAIGSVAPGHSFRKVTLTKPTFCHLCSDFIWGLAGFLCDVCNFMSHEKCLKQVKTPCTSIAPSLVRVPVAHCFGSLGLYKRKFCVVCRKSLEVPAFRCEVCELHVHPDCVPFACSDCRQCHQDGQHDYDTYHHHWREGNLPSGARCEVCRKTCGSSDVLAGVRCEWCGVQAHSVCSTALTPECTFGRLRSMVLPPSCVRLLSRNFSKMHCFRIPETMVLELGDGDDGLDGSAAVGTGREVSAATESTKQTLKIFDGNDSMRKNQFRLVTVSRLAR... | cAMP-mediated signaling diacylglycerol metabolic process G protein-coupled receptor signaling pathway glycerolipid metabolic process intracellular signal transduction lipid phosphorylation negative regulation of gene expression negative regulation of peptidyl-threonine phosphorylation phosphatidic acid biosynthetic pro... |
steroid metabolic process | cytoplasm; cytosol | alditol:NADP+ 1-oxidoreductase activity aldo-keto reductase (NADP) activity farnesol dehydrogenase activity ketosteroid monooxygenase activity steroid dehydrogenase activity | Rattus norvegicus | Cytoplasm NADP Oxidoreductase Reference proteome | MDLKHSRSVK | MDLKHSRSVKLNDGNLMPVLGFGTFASKEIPKSKAAEATKVAIDVGFRHIDAAYFYQNEEEVGQALRDKMADGTVKREDLFYTTKIWITFLRPELVRQCLERSLKKLGLDYVDLCIIHIPIAMKPGEELLPKDANGKFIFDTVDIRDTWEALEKCKDAGLSKSIGVSNFNHKQLELILNKPRLKYKPTCNQVECHPYLNQSKLLEFCKSKDIVLVAYSALGSHRDSSWVSSDSPYLLEDPVLMTIAKKHNQTPGQVALRYQLQRGVVVLAKSFNEKRIKENFQVFDFELTPEDMKTIDSLNRNFRYSQMAFALDHPDYPF... | steroid metabolic process cytoplasm; cytosol alditol:NADP+ 1-oxidoreductase activity aldo-keto reductase (NADP) activity farnesol dehydrogenase activity ketosteroid monooxygenase activity steroid dehydrogenase activity Rattus norvegicus Cytoplasm NADP Oxidoreductase Reference proteome MDLKHSRSVK MDLKHSRSVKLNDGNLMPVLGFG... |
negative regulation of short-term synaptic potentiation negative regulation of SNARE complex assembly neuromuscular process controlling posture regulation of calcium-dependent activation of synaptic vesicle fusion synaptic vesicle fusion to presynaptic active zone membrane | axon terminus; dendritic spine; glutamatergic synapse; membrane; neuron projection; plasma membrane; postsynaptic density membrane; presynapse; presynaptic membrane; synaptic vesicle; synaptic vesicle membrane; vesicle | SH3 domain binding syntaxin-1 binding | Rattus norvegicus | Cell membrane Cell projection Cytoplasmic vesicle Membrane Methylation Phosphoprotein Postsynaptic cell membrane Reference proteome Synapse Transmembrane Transmembrane helix | MAASSSEVSE | MAASSSEVSEMKGVEDSSNTHSEGPRHSEEGMGPVQVVAENLDQPEALQSGPDTTAAPVDSGPKAELAPETTETPVETPETVQATDLSVNPGEDSKTCPSPKEACQEPASRPEVNREATAEQGAEQQSAAPPEPTSEQALQLNTQSDPQPTSQPPPKPPLQAEPPTQENPTTEVLTESTGEKQENGAVVPLQAGDGEEGPAPQPHSPPSTKTPPANGAPPRVLQKLVEEDRIGRAHGGHPGSPRGSLSRHPSSQLAGPGVEGGEGTQKPRDYIILAILSCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLL... | negative regulation of short-term synaptic potentiation negative regulation of SNARE complex assembly neuromuscular process controlling posture regulation of calcium-dependent activation of synaptic vesicle fusion synaptic vesicle fusion to presynaptic active zone membrane axon terminus; dendritic spine; glutamatergic ... |
actin filament organization cell junction assembly cell migration establishment of epithelial cell apical/basal polarity filopodium assembly negative regulation of small GTPase mediated signal transduction phagocytosis, engulfment positive regulation of GTPase activity regulation of actin cytoskeleton organization regu... | adherens junction; bicellular tight junction; cell leading edge; cytosol; exocyst; lamellipodium; nucleus; phagocytic cup | GTPase activator activity semaphorin receptor binding SH3 domain binding | Rattus norvegicus | Cell junction Cell projection Cytoplasm GTPase activation Nucleus Phagocytosis Phosphoprotein Reference proteome SH3-binding Tight junction | MMKRQLHRMR | MMKRQLHRMRQLAHTGSSGRTPETAEFLGEDLLQVEQRLEPAKRAAHNVHKRLQACLQGQSGADMDKRVKKLPLMALSTAMAESFKELDPDSSMGKALEMSCAIQNQLARILAEFEMTLERDVLQPLNRLSEEELPAILKRKKSLQKLVSDWNTLKSRLSQAAKNSGSSQSLGGGSSSHTHMATANKVETLKEDEEELKRKVEQCKDEYLADLYHFSTKEDSYANYFTHLLEIQADYHRKSLTSLDTALAELRDNHSQADSSPLTTAAPFSRVYGVSLRTHLQDLGRDIALPIEACVLLLLSEGMQEEGLFRLAAGASVL... | actin filament organization cell junction assembly cell migration establishment of epithelial cell apical/basal polarity filopodium assembly negative regulation of small GTPase mediated signal transduction phagocytosis, engulfment positive regulation of GTPase activity regulation of actin cytoskeleton organization regu... |
negative regulation of DNA-templated transcription phosphorylation positive regulation of apoptotic process positive regulation of JNK cascade smoothened signaling pathway | cytoplasm | ATP binding bHLH transcription factor binding JUN kinase kinase kinase activity protein kinase activity protein serine kinase activity protein serine/threonine kinase activity transcription corepressor activity | Rattus norvegicus | ATP-binding Kinase Methylation Nucleotide-binding Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase SH3 domain Transferase | MEEEEGAAAR | MEEEEGAAAREWGATPAGPVWTAVFDYEAVGDEELTLRRGDRVQVLSQDCAVSGDEGWWTGQLPSGRVGVFPSNYVAPAAPAAPTDLQLPQEIPFHELQLEEIIGVGGFGKVYRALWRGEEVAVKAARLDPERDPAVTAEQVRQEARLFGALQHPNIIALRGACLSPPNLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLAREWHKTTKMSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKL... | negative regulation of DNA-templated transcription phosphorylation positive regulation of apoptotic process positive regulation of JNK cascade smoothened signaling pathway cytoplasm ATP binding bHLH transcription factor binding JUN kinase kinase kinase activity protein kinase activity protein serine kinase activity pro... |
animal organ morphogenesis determination of left/right symmetry heart development phosphorylation regulation of hippo signaling | centrosome; ciliary base; ciliary inversin compartment; cilium; cytoplasm | ATP binding metal ion binding protein serine kinase activity protein serine/threonine kinase activity | Rattus norvegicus | ATP-binding Cell projection Cilium Cytoplasm Cytoskeleton Disease variant Kinase Magnesium Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transferase | MEKYERIRVV | MEKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEEETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIRALLNIHTDVGSVRMRRAEKCLTPGTPMAPGSTGSRATSARCRGVPRGPVRPAIPPPLSSV... | animal organ morphogenesis determination of left/right symmetry heart development phosphorylation regulation of hippo signaling centrosome; ciliary base; ciliary inversin compartment; cilium; cytoplasm ATP binding metal ion binding protein serine kinase activity protein serine/threonine kinase activity Rattus norvegicu... |
cilium assembly in utero embryonic development phosphatidylinositol dephosphorylation signal transduction | clathrin-coated pit; clathrin-coated vesicle; cytoplasm; early endosome; early endosome membrane; membrane; nucleus; phagocytic vesicle membrane; photoreceptor outer segment; plasma membrane; trans-Golgi network | GTPase activator activity inositol phosphate phosphatase activity inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity inositol-1,4,5-trisphosphate 5-phosphatase activity inositol-polyphosphate 5-phosphatase activity phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity phosphatidylinositol-4,5-bisphosph... | Rattus norvegicus | Cell projection Cilium Cilium biogenesis/degradation Coated pit Cytoplasmic vesicle Endosome Golgi apparatus Hydrolase Lipid metabolism Membrane Reference proteome | MEPRLPIGAQ | MEPRLPIGAQPLACLHMVAGLEMKGPLREPCVLTLARRNGQYELIIQLHGKEQHVQDIIPINSHFRCVQEAEETLLIDIASNSGCKIRVQGDWTRERHFEIPDEERCLKFLSEVLAAQEAQSQLLVPEQKDSSNWYQKLDTKDKPAYSGLLGFEDNFSSMNLDKKMNTQNPPTGIHREPPPPPSSNRMLPREKEALNKEQPKVTNTMRKLFAPNSQSGQREGLIKHILAKREKEYVNIQSFRFFVGTWNVNGQSPDSSLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWAMAVERGLPSKAKYKKVQLVRL... | cilium assembly in utero embryonic development phosphatidylinositol dephosphorylation signal transduction clathrin-coated pit; clathrin-coated vesicle; cytoplasm; early endosome; early endosome membrane; membrane; nucleus; phagocytic vesicle membrane; photoreceptor outer segment; plasma membrane; trans-Golgi network GT... |
autophagosome assembly fibroblast activation negative regulation of smoothened signaling pathway nucleophagy piecemeal microautophagy of the nucleus positive regulation of smoothened signaling pathway protein autophosphorylation regulation of autophagy response to starvation reticulophagy smoothened signaling pathway | autophagosome; cytoplasm; cytosol; phagophore assembly site; phagophore assembly site membrane | ATP binding protein serine kinase activity protein serine/threonine kinase activity | Rattus norvegicus | ATP-binding Autophagy Cytoplasm Kinase Nucleotide-binding Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transferase | MAGSGWGLPR | MAGSGWGLPRLDGFILTERLGSGTYATVYKAYAKKATREVVAIKCVAKKSLNKASVENLLTEIEILKGIRHPHIVQLKDFQWDNDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCRRQYDARVDLWSVGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPQLSLDCRDLLQRLLERDPSHRISFQDFFAHPWVDLEHMPSGESLAQATALVVEAVKKDQEGDAAAALSLYCKALDFFVPALHY... | autophagosome assembly fibroblast activation negative regulation of smoothened signaling pathway nucleophagy piecemeal microautophagy of the nucleus positive regulation of smoothened signaling pathway protein autophosphorylation regulation of autophagy response to starvation reticulophagy smoothened signaling pathway a... |
fatty acid beta-oxidation fatty acid elongation fatty acid homeostasis long-chain fatty acid catabolic process long-chain fatty acid import into peroxisome myelin maintenance negative regulation of cytokine production involved in inflammatory response negative regulation of reactive oxygen species biosynthetic process ... | cytoplasm; endoplasmic reticulum membrane; lysosomal membrane; mitochondrial membrane; perinuclear region of cytoplasm; peroxisomal membrane; peroxisome | ABC-type fatty-acyl-CoA transporter activity acyl-CoA hydrolase activity ADP binding ATP binding ATP hydrolysis activity ATPase-coupled transmembrane transporter activity enzyme binding identical protein binding long-chain fatty acid transporter activity protein heterodimerization activity protein homodimerization acti... | Rattus norvegicus | ATP-binding Endoplasmic reticulum Glycoprotein Hydrolase Lysosome Membrane Mitochondrion Nucleotide-binding Peroxisome Reference proteome Translocase Transmembrane Transmembrane helix Transport | MPVLSTPSRP | MPVLSTPSRPSRVTTLKRTAVVLALTAYGVHKIYPLVRQCLTPARGPQVPAGESTQEASGATTAKAGMNRVFLQRLLVLLRLLFPGVLCRETGLLALHSAALVSRTFLSVYVARLDGRLARCIVRKDPRAFSWQLLQWLLIALPATFINSAIRYLEGQLALSFRSRLVAHAYGLYFSQQTYYRVSNMDGRLRNPDQSLTEDMVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELALLQHSYQDLASQINL... | fatty acid beta-oxidation fatty acid elongation fatty acid homeostasis long-chain fatty acid catabolic process long-chain fatty acid import into peroxisome myelin maintenance negative regulation of cytokine production involved in inflammatory response negative regulation of reactive oxygen species biosynthetic process ... |
cell population proliferation common myeloid progenitor cell proliferation erythrocyte differentiation erythrocyte maturation gene expression granulocyte differentiation hematopoietic stem cell homeostasis in utero embryonic development leukocyte proliferation macrophage homeostasis mitotic cell cycle monoubiquitinated... | cytoplasm; nucleus; PR-DUB complex | chromatin binding chromatin DNA binding cysteine-type deubiquitinase activity histone H2A deubiquitinase activity | Rattus norvegicus | Chromatin regulator Coiled coil Cytoplasm Hydrolase Nucleus Phosphoprotein Protease Reference proteome Thiol protease Ubl conjugation Ubl conjugation pathway | MNKGWLELES | MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNSMFFAHQLIPNSCATHALLSVLLNCSNVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRVKYEARLHVLKGNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKPASSKSPFGLEAGRTPAASECTHTDGAEEVAGSC... | cell population proliferation common myeloid progenitor cell proliferation erythrocyte differentiation erythrocyte maturation gene expression granulocyte differentiation hematopoietic stem cell homeostasis in utero embryonic development leukocyte proliferation macrophage homeostasis mitotic cell cycle monoubiquitinated... |
CDP-diacylglycerol biosynthetic process fatty acid metabolic process glycerol-3-phosphate metabolic process phosphatidic acid biosynthetic process phospholipid biosynthetic process piRNA processing triglyceride biosynthetic process | mitochondrial membrane; mitochondrial outer membrane; mitochondrion | 1-acylglycerol-3-phosphate O-acyltransferase activity glycerol-3-phosphate O-acyltransferase activity sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity | Rattus norvegicus | Acyltransferase Membrane Mitochondrion Mitochondrion outer membrane Reference proteome Transferase Transmembrane Transmembrane helix | METMLKSNPQ | METMLKSNPQMQQRNNHSGQETSLWSSGFGMKMEAITPFLGKYRPFMGRCCQTCTPKSWESLFHRSIMDLGFCNVILVKEENTRFRGWLVRRLCYFLWSLEQHIPTSSDASQMIMENTGVQNILLGKVPGAAGEGQAPDLVKKEVQRILGHIQTTPRPFLLRLFSWALLWFLNRLFLNVQLHKGQMKMVHKAAQEGSPLVFLSTHKSLLDGFLLPFVLFSQGLGVLRVALDSRTCSPALRALLRKLGGLFLPPEANLSLDSSEGILARAVVRATVEQLLTSGQPLLIFLEEAPGYPGPRLSALGQAWLGLVVQAVQAGIV... | CDP-diacylglycerol biosynthetic process fatty acid metabolic process glycerol-3-phosphate metabolic process phosphatidic acid biosynthetic process phospholipid biosynthetic process piRNA processing triglyceride biosynthetic process mitochondrial membrane; mitochondrial outer membrane; mitochondrion 1-acylglycerol-3-pho... |
autophagosome assembly cellular response to leukemia inhibitory factor Golgi organization membrane fusion negative regulation of ERAD pathway nuclear membrane reassembly proteasome-mediated ubiquitin-dependent protein catabolic process regulation of gene expression regulation of protein catabolic process regulation of ... | cis-Golgi network; cytosol; dendrite; endoplasmic reticulum; Golgi apparatus; nucleus; perikaryon | acetylcholine receptor binding ubiquitin binding | Rattus norvegicus | Cell projection Cytoplasm Endoplasmic reticulum Golgi apparatus Nucleus Reference proteome Ubl conjugation | MKEVDNLDSI | MKEVDNLDSIKEEWVCETGPPDNQPLNDNPQKDCEYFVDSLFEEAEKAGAKCLSPTEQKKQVDVNIKLWKNGFTVNDDFRSYSDGASQQFLNSIKKGELPSELQGVFDKDEVDVKVEDKKNEVCMSTKPVFQPFSGQGHRLGSATPRIVSKAKSIEVDNKSTLSAVSLNNLEPITRIQIWLANGERTVQRFNISHRVSHIKDFIEKYQGTQRSPPFALATALPFLRFLDETLTLEEADLQNAVIIQRLQKTAEPFRKL | autophagosome assembly cellular response to leukemia inhibitory factor Golgi organization membrane fusion negative regulation of ERAD pathway nuclear membrane reassembly proteasome-mediated ubiquitin-dependent protein catabolic process regulation of gene expression regulation of protein catabolic process regulation of ... |
integrin-mediated signaling pathway protein localization to plasma membrane T cell receptor signaling pathway | anchoring junction; cytoplasm; nucleus; plasma membrane; protein-containing complex | lipid binding protein-containing complex binding | Rattus norvegicus | Acetylation Cell junction Coiled coil Cytoplasm Direct protein sequencing Nucleus Phosphoprotein Reference proteome Repeat SH3 domain | MDGKTDVKSL | MDGKTDVKSLMAKFNTGSNPTEEVSTSSRPFKVAGQNSPSGIQSKKNLFDNQGNASPPAGPSNMSKFGTTKPPLAAKPTYEEKSEKEPKPPFLKPTGVSPRFGTQPNSVSRDPEVKVGFLKPVSPKPTSLTKEDSKPVILRPPGNKLHNLNQESDLKTLGPKPGSTPPVPENDLKPGFSKIAGAKSKFMPAPQDADSKPRFPRHTYGQKPSLSTEDAQEEESIPKNTPVQKGSPVQLGAKSRGSPFKPAKEDPEDKDHGTPSSPFAGVVLKPAASRGSPGLSKNSEEKKEERKTDIPKNIFLNKLNQEEPARFPKAPSKL... | integrin-mediated signaling pathway protein localization to plasma membrane T cell receptor signaling pathway anchoring junction; cytoplasm; nucleus; plasma membrane; protein-containing complex lipid binding protein-containing complex binding Rattus norvegicus Acetylation Cell junction Coiled coil Cytoplasm Direct prot... |
amino acid transmembrane transport erythrocyte differentiation glutamine secretion glutamine transport L-aspartate import across plasma membrane L-glutamine import across plasma membrane L-serine transport neutral amino acid transport protein homotrimerization transport across blood-brain barrier | basal plasma membrane; melanosome; membrane; plasma membrane | antiporter activity L-aspartate transmembrane transporter activity L-glutamine transmembrane transporter activity L-serine transmembrane transporter activity ligand-gated channel activity metal ion binding neutral L-amino acid transmembrane transporter activity symporter activity | Rattus norvegicus | Acetylation Amino-acid transport Antiport Cell membrane Glycoprotein Membrane Metal-binding Phosphoprotein Reference proteome Sodium Symport Transmembrane Transmembrane helix Transport | MAVDPPKADP | MAVDPPKADPKGVVAVDPTANCGSGLKSREDQGAKAGGCCSSRDQVCRCLRANLLVLLTVAAAVAGVVLGLGVSAAGGAEALGHARFTAFAFPGELLLRLLEMIILPLVVCSLIGGAASLDPSALGRLGAWALLFFLVTTLLSSALGVALALALKPGAAFAAINSSVVDSSVHRAPTKEVLDSFLELLRNMFPSNLVSASAAFRIFATSYVSKDINTSGIHPCGACPQRSNATMDQPHCEMKMNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNDATMVLVSWIMWYAPIGILFLVAGKIVEMKDIRQLFIGLGKYI... | amino acid transmembrane transport erythrocyte differentiation glutamine secretion glutamine transport L-aspartate import across plasma membrane L-glutamine import across plasma membrane L-serine transport neutral amino acid transport protein homotrimerization transport across blood-brain barrier basal plasma membrane;... |
axon extension brain-derived neurotrophic factor receptor signaling pathway dendrite extension dendritic spine development establishment of cell polarity neuron projection morphogenesis potassium ion transmembrane transport proton transmembrane transport regulation of intracellular pH regulation of neurotrophin TRK rec... | axon terminus; axonal spine; cytoplasmic vesicle; dendrite; early endosome; early endosome membrane; endoplasmic reticulum membrane; endosome; glutamatergic synapse; late endosome; late endosome membrane; plasma membrane; recycling endosome; recycling endosome membrane; Schaffer collateral - CA1 synapse; synapse | identical protein binding potassium:proton antiporter activity sodium:proton antiporter activity | Rattus norvegicus | Antiport Cell membrane Endosome Glycoprotein Ion transport Isopeptide bond Membrane Reference proteome Sodium Sodium transport Transmembrane Transmembrane helix Transport Ubl conjugation | MTSPKPWARS | MTSPKPWARSAGSCQTQRAVRTRKKECREEGESDTEKGPAASSASAQCSFPKRVSFFGWAGALDSSGGTTRAMDEEIVSEKQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQSSPTTLLVNVSGKFYEYTLKGEISSHELNNVQDNEMLRKVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSS... | axon extension brain-derived neurotrophic factor receptor signaling pathway dendrite extension dendritic spine development establishment of cell polarity neuron projection morphogenesis potassium ion transmembrane transport proton transmembrane transport regulation of intracellular pH regulation of neurotrophin TRK rec... |
cell differentiation gamma-delta T cell proliferation mRNA destabilization mRNA export from nucleus mRNA processing non-membrane-bounded organelle assembly oxidative single-stranded RNA demethylation regulation of mRNA stability regulation of translation response to hypoxia spermatogenesis | cytosol; Golgi apparatus; nuclear speck; nucleus; paraspeckles | 2-oxoglutarate-dependent dioxygenase activity metal ion binding molecular condensate scaffold activity mRNA N6-methyladenosine dioxygenase activity oxidative RNA demethylase activity | Rattus norvegicus | Acetylation Coiled coil Differentiation Dioxygenase Iron Isopeptide bond Metal-binding Methylation Nucleus Oxidoreductase Phosphoprotein Reference proteome Spermatogenesis Ubl conjugation | MAAASGYTDL | MAAASGYTDLREKLKSMTSRDNYKAGSREAAAAAAAAVAAAAAAAAAAEPYPVSGTTKRKYQEDSDPERSDYEEHQLQKEEEARKVKSGIRQIRLFSQDECSKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKYFFGEGYTYGAQLQKRGPGQERLYPPGDVDEIPEWVHQLVIQKLVEHRVIPEGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVSEPVLSLPVRRGSVTVLSGYAADEITHCIRPQDIKERRAVIILRKTRLDAPRLETKSLSSSTLPPSYASDRLSGNTRDPA... | cell differentiation gamma-delta T cell proliferation mRNA destabilization mRNA export from nucleus mRNA processing non-membrane-bounded organelle assembly oxidative single-stranded RNA demethylation regulation of mRNA stability regulation of translation response to hypoxia spermatogenesis cytosol; Golgi apparatus; nuc... |
arachidonic acid metabolic process ceramide biosynthetic process establishment of skin barrier fat cell differentiation hepoxilin biosynthetic process linoleic acid metabolic process lipid oxidation lipoxygenase pathway peroxisome proliferator activated receptor signaling pathway sensory perception of pain sphingolipid... | cytoplasm | hepoxilin A3 synthase activity hydroperoxy icosatetraenoate dehydratase activity hydroperoxy icosatetraenoate isomerase activity intramolecular hydroxytransferase activity iron ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | Rattus norvegicus | Cytoplasm Dioxygenase Fatty acid metabolism Iron Isomerase Lipid metabolism Lyase Metal-binding Oxidoreductase Reference proteome | MAVYRLCVTT | MAVYRLCVTTGSYLKAGTLDNIYATLVGTCGESPKQKLDRVGRDFATGSVQKYKVRCASELGEILLLRLHKERFAFFCKDPWYCSRICVTTPDGSVVHFPCYQWIDGYCTVELRPGTARTICQDALPLLLDHRKRELQARQECYRWKIYAPGFPRMVDVSSFEEMESDKKFALTKTAPCADQDDNSGNRYLPGFPMKVDIPSLLHMEPNIRYSATKTASLIFNALPASLGMKIRGLLDRKGSWKRLDDIRNIFWCHKTFTSEYVTEHWCEDSFFGYQYLNGVNPIMLHCLSSLPSKLPVTNDMVAPLLGPGTCLQTELER... | arachidonic acid metabolic process ceramide biosynthetic process establishment of skin barrier fat cell differentiation hepoxilin biosynthetic process linoleic acid metabolic process lipid oxidation lipoxygenase pathway peroxisome proliferator activated receptor signaling pathway sensory perception of pain sphingolipid... |
cellular response to calcium ion cellular response to hormone stimulus female pregnancy positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II response to cAMP response to cocaine response to corticosterone response to ethanol response to mechanical stimulus response ... | cytosol; nucleoplasm; nucleus | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific double-stranded DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA bin... | Rattus norvegicus | Disulfide bond Nucleus Phosphoprotein Reference proteome | MFQAFPGDYD | MFQAFPGDYDSGSRCSSSPSAESQYLSSVDSFGSPPTAAASQECAGLGEMPGSFVPTVTAITTSQDLQWLVQPTLISSMAQSQGQPLASQPPAVDPYDMPGTSYSTPGLSAYSTGGASGSGGPSTSTSTSGPVSARPARARPRRPREETLTPEEEEKRRVRRERNKLAAAKCRNRRRELTDRLQAETDQLEEEKAELESEIAELQKEKERLEFVLVAHKPGCKIPYEEGPGPGPLAEVRDLPGSTSAKEDGFGWLLPPPPPPPLPFQSSRDAPPNLTASLFTHSEVQVLGDPFPVVSPSYTSSFVLTCPEVSAFAGSQRT... | cellular response to calcium ion cellular response to hormone stimulus female pregnancy positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II response to cAMP response to cocaine response to corticosterone response to ethanol response to mechanical stimulus response ... |
actin cytoskeleton organization axonogenesis cell division DNA damage response ERAD pathway establishment of cell polarity exocytosis G2/M transition of mitotic cell cycle intracellular signal transduction intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress microtubule cytoskeleton organiz... | centrosome; cytoplasm; distal axon; endoplasmic reticulum; nucleus; perinuclear region of cytoplasm | ATP binding ATPase binding magnesium ion binding protein kinase binding protein serine kinase activity protein serine/threonine kinase activity tau-protein kinase activity | Rattus norvegicus | Alternative splicing Apoptosis ATP-binding Cell cycle Cell division Cytoplasm Cytoskeleton Endoplasmic reticulum Exocytosis Kinase Magnesium Metal-binding Mitosis Neurogenesis Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase Ubl conjugation | MTSTGKDGGG | MTSTGKDGGGAQHAQYVGPYRLEKTLGKGQTGLVKLGIHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDERNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWYIGGKNEPEPEQPIPRKVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNKLL... | actin cytoskeleton organization axonogenesis cell division DNA damage response ERAD pathway establishment of cell polarity exocytosis G2/M transition of mitotic cell cycle intracellular signal transduction intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress microtubule cytoskeleton organiz... |
amino acid transmembrane transport glycine betaine transport L-arginine transmembrane transport leucine transport neutral amino acid transport nitric oxide biosynthetic process ornithine transport | plasma membrane | arginine binding basic amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity L-arginine transmembrane transporter activity L-lysine:L-arginine antiporter activity | Rattus norvegicus | Amino-acid transport Cell membrane Membrane Reference proteome Transmembrane Transmembrane helix Transport | MEARELGSPT | MEARELGSPTPTYHLLPKANQHTVKEDASSPSQGSPETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLKYTASYGLSLVVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLIVEPTSQAIIAITFANYIIKPSFPTCDPPYVACRLLAAACVCLLTFVNCAYVKWGTRVQDTFTYAKVLALIAIIIMGLVKLCQGHTEHFQDAFKGSSWNVGDLSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNIQDVHKSDAVAVTFADQTFGMFSWTI... | amino acid transmembrane transport glycine betaine transport L-arginine transmembrane transport leucine transport neutral amino acid transport nitric oxide biosynthetic process ornithine transport plasma membrane arginine binding basic amino acid transmembrane transporter activity L-amino acid transmembrane transporter... |
adenosine metabolic process allantoin metabolic process amide catabolic process dGMP catabolic process dGMP metabolic process GMP catabolic process GMP catabolic process to guanine GMP metabolic process IMP catabolic process IMP metabolic process negative regulation of defense response to virus by host protein K48-link... | cytoplasm; cytosol | 5'-nucleotidase activity ATP binding GMP 5'-nucleotidase activity identical protein binding IMP 5'-nucleotidase activity metal ion binding nucleoside phosphotransferase activity ubiquitin protein ligase activity | Rattus norvegicus | Allosteric enzyme ATP-binding Cytoplasm Hydrolase Magnesium Metal-binding Nucleotide metabolism Nucleotide-binding Phosphoprotein Reference proteome Transferase | MMTSWSDRLQ | MMTSWSDRLQNAADVPANMDKHALKKYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFELTVERLVSIGYPQELLNFAYDSTFPTRGLVFDTLYGNLLKVDAYGNLLVCAHGFNFIRGPETREQYPNKFIQRDDTERFYILNTLFNLPETYLLACLVDFFTNCPRYTSCDTGFKDGDLFMSYRSMFQDVRDAVDWVHYKGSLKEKTVENLEKYVVKDGKLPLLLSRMKEVGKVFLATNSDYKYTDKIMTYLFDFPHGPKPGSSHRPWQSYFDLILVDARKPLFFGEGTVLRQVDTKTGKLKIGTYTGP... | adenosine metabolic process allantoin metabolic process amide catabolic process dGMP catabolic process dGMP metabolic process GMP catabolic process GMP catabolic process to guanine GMP metabolic process IMP catabolic process IMP metabolic process negative regulation of defense response to virus by host protein K48-link... |
mitochondrial fusion negative regulation of mitophagy protein K11-linked deubiquitination protein K6-linked deubiquitination proteolysis | cytosol; mitochondrial outer membrane; mitochondrion; nucleus | cysteine-type deubiquitinase activity cysteine-type endopeptidase activity | Rattus norvegicus | Hydrolase Isopeptide bond Membrane Mitochondrion Mitochondrion outer membrane Protease Reference proteome Thiol protease Transmembrane Transmembrane helix Ubl conjugation Ubl conjugation pathway | MLSSRAQAAR | MLSSRAQAARTAADKALQRFLRTGAAVRYKVMKNWGVIGGIAAALAAGIYVIWGPITERKKRRKGLVPGLVNLGNTCFMNSLLQGLSACPAFVKWLEEFTTQYSRDQQGPHTHQCLSLTLLSLLKALSCQEVTEEEVLDASCLLDVLRMYRWQISSFEEQDAHELFHVITSSLEDERDRQPRVTHLFDVHSLEQQSEMAPRQVTCHTRGSPHPTTNPWKSQHPFHGRLSSNMVCKHCEHQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEAKGTQNGEKVEHQRTTFVKQLKLGKLPQC... | mitochondrial fusion negative regulation of mitophagy protein K11-linked deubiquitination protein K6-linked deubiquitination proteolysis cytosol; mitochondrial outer membrane; mitochondrion; nucleus cysteine-type deubiquitinase activity cysteine-type endopeptidase activity Rattus norvegicus Hydrolase Isopeptide bond Me... |
cell differentiation meiotic cell cycle piRNA processing positive regulation of viral genome replication protein folding regulatory ncRNA-mediated gene silencing siRNA-mediated retrotransposon silencing by heterochromatin formation spermatogenesis | cytoplasm; cytosol; synaptonemal complex | Hsp90 protein binding identical protein binding | Rattus norvegicus | Chromosome Cytoplasm Differentiation Meiosis Nucleus Reference proteome Repeat RNA-mediated gene silencing Spermatogenesis TPR repeat | MSVFSRLRNG | MSVFSRLRNGIPPSRDDCQSPYERLSQRMLDISGDRGVLKDIIREGAGDPVTPDASVLVKYSGYLEHMDKPFDSNCFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPTYAYGTLGCPPLIPPNATVLFEIELIDFLDSAESDKFCALSAEQQEQFPLQKVLKVAATEREFGNYLFRQNRFCDAKVRYKRALLLLHRRLAICEEQHLVEPAELLVLLNLSFVYLKLDRPAMALRYGEQALLIDKRNAKALFRCGQACLLLTEYEQARDFLVRAQKEQPCNHDINNELKKLSSHYRDYVDREREMCHRMFAPCGS... | cell differentiation meiotic cell cycle piRNA processing positive regulation of viral genome replication protein folding regulatory ncRNA-mediated gene silencing siRNA-mediated retrotransposon silencing by heterochromatin formation spermatogenesis cytoplasm; cytosol; synaptonemal complex Hsp90 protein binding identical... |
arachidonic acid metabolic process hepoxilin biosynthetic process linoleic acid metabolic process lipid oxidation lipoxygenase pathway | cytosol; plasma membrane | arachidonate 12(S)-lipoxygenase activity arachidonate 15-lipoxygenase activity iron ion binding linoleate 13S-lipoxygenase activity | Rattus norvegicus | Cytoplasm Dioxygenase Fatty acid metabolism Iron Lipid metabolism Metal-binding Oxidoreductase Reference proteome | MGKYKILVVT | MGKYKILVVTGDSLLAGSTNLVQLWLVGEHAEADLGKQLRPLRGRKTELEIDVPLHLGRLLVVKLRKHKGLLDSDWFCKWITVQGPGIQGEAFFPCYSWVQGKETIYLPEGTALKVNDDTKNLFRKYREQELEDRRNVYRWGSWKEGLILPIAGSTERDLPRNQRFMEDKDLDFSLSLAKVLKDFAIKGTLDFVSRVQHLEDYQKVFPHSKTALAGRVRDSWKEDALFGYQFLNGANPMLLRRSKRLPARLVLPPGMEDLQTQLEKELKAGSLFEADFSLLDGVKPNVIIFKQQHVAAPLVMLKLQSDGRLLPMVIQLQP... | arachidonic acid metabolic process hepoxilin biosynthetic process linoleic acid metabolic process lipid oxidation lipoxygenase pathway cytosol; plasma membrane arachidonate 12(S)-lipoxygenase activity arachidonate 15-lipoxygenase activity iron ion binding linoleate 13S-lipoxygenase activity Rattus norvegicus Cytoplasm ... |
cellular response to nerve growth factor stimulus endocytic recycling endocytosis neuron projection development plasma membrane tubulation protein localization to endosome protein targeting to membrane protein transport receptor-mediated endocytosis slow endocytic recycling | cytoplasmic side of endosome membrane; endosome membrane; late endosome; late endosome membrane; recycling endosome membrane | identical protein binding metal ion binding phosphatidic acid binding small GTPase binding | Rattus norvegicus | Coiled coil Endocytosis Endosome LIM domain Membrane Metal-binding Phosphoprotein Protein transport Reference proteome Transport Zinc | MAGPRGALLA | MAGPRGALLAWCRRQCEGYRGVDIRDLSSSFRDGLAFCAILHRHRPDLLDFQSLSKENVFENNRLAFEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFTSSGQAAASPPKPGKDPAAPSPTSTSPAVQPGEEAQGDDLSPDSLSEQGKPQPPSSACAACGQRVHLVQRYLAEGRLYHRHCFRCRQCSSTLVPGSYSSGPEEGTFVCAERCTRLGLGGRSGTRPLSLQKQQPAAAAEAKDGEDSDLSKSVVVVAAEADGLQASSEVQPHTLTKPPLPSKPQDLASPPVSRPTPAPRKASESSALTPPTPRPR... | cellular response to nerve growth factor stimulus endocytic recycling endocytosis neuron projection development plasma membrane tubulation protein localization to endosome protein targeting to membrane protein transport receptor-mediated endocytosis slow endocytic recycling cytoplasmic side of endosome membrane; endoso... |
astral microtubule organization cell division microtubule bundle formation microtubule nucleation by microtubule organizing center microtubule polymerization myelin assembly negative regulation of tubulin deacetylation oligodendrocyte development oligodendrocyte differentiation positive regulation of myelination positi... | cytoplasm; Golgi apparatus; microtubule organizing center; mitotic spindle; nucleus; perinuclear region of cytoplasm; postsynaptic Golgi apparatus | GTPase activity magnesium ion binding microtubule binding microtubule nucleator activity protein dimerization activity protein homodimerization activity tubulin binding | Rattus norvegicus | Cell cycle Cell division Cytoplasm Cytoskeleton Glycoprotein Golgi apparatus Hydrolase Magnesium Metal-binding Mitosis Nucleus Phosphoprotein Reference proteome Zinc | MADSKAKPTK | MADSKAKPTKAANKTPPKSPGDPAKAAKRLSLESEGANEGAAAAPELSALEEAFRRFAVHGDTRATGKEMHGKNWSKLCKDCHVIDGKNVTVTDVDIVFSKIKGKSCRTITFEQFQEALEELAKKRFKDKSSEEAVREVHRLIEGRAPVISGVTKAVSSPTVSRLTDTSKFTGSHKERFDQSGKGKGKAGRVDLVDESGYVPGYKHAGTYDQKVQGGK | astral microtubule organization cell division microtubule bundle formation microtubule nucleation by microtubule organizing center microtubule polymerization myelin assembly negative regulation of tubulin deacetylation oligodendrocyte development oligodendrocyte differentiation positive regulation of myelination positi... |
cilium assembly dendrite morphogenesis intracellular signal transduction neuron migration neuronal action potential positive regulation of smoothened signaling pathway regulation of cilium assembly regulation of Wnt signaling pathway sensory perception of sound synaptic transmission, glutamatergic visual learning | axoneme; centriolar satellite; cilium; cytoplasm; cytosol; kinocilium; microtubule; microtubule organizing center; mitotic spindle | kinesin binding | Rattus norvegicus | Cell projection Cilium biogenesis/degradation Cytoplasm Cytoskeleton Neurogenesis Phosphoprotein Reference proteome Repeat | MNGPSPRSSH | MNGPSPRSSHLSQPVVKSVLVYRNGDPFFAGRRVVIHEKKVSSFDIFLKEVTGGVQAPFGAVRNIYTPRTGHRIRKLDQIESGGNYVAGGQEAFKKLNYLDIGEIKKRPMEAVNTEVKPVIHSKINVSARFRKALHEPCTIFLIANGDLISPASRLLIPRKALNQWDHVLQMVTEKITLRSGAVHRLYTLEGKLVESGAELENGQFYVAVGRDKFKRLPYSELLFDKSAMRRPYGQKASSLPPMVGSRKSKGSGNYRQSKSTIGSSDNSSPQPLKRKGKKDSNSEKPTKVKQSVKSKNSHQAIPDNDEGIFKAGAERSET... | cilium assembly dendrite morphogenesis intracellular signal transduction neuron migration neuronal action potential positive regulation of smoothened signaling pathway regulation of cilium assembly regulation of Wnt signaling pathway sensory perception of sound synaptic transmission, glutamatergic visual learning axone... |
arachidonic acid metabolic process arachidonic acid secretion cardiolipin metabolic process fatty acid metabolic process intracellular signal transduction linoleic acid metabolic process lipid homeostasis phosphatidylcholine catabolic process phosphatidylethanolamine catabolic process prostaglandin biosynthetic process... | endoplasmic reticulum membrane; membrane; mitochondrial membrane; mitochondrion; peroxisomal membrane; peroxisome | calcium-independent phospholipase A2 activity lysophospholipase activity phosphatidyl phospholipase B activity phospholipase A1 activity | Rattus norvegicus | Endoplasmic reticulum Hydrolase Lipid degradation Lipid metabolism Membrane Microsome Mitochondrion Peroxisome Reference proteome Transmembrane Transmembrane helix | MSINLTLDIY | MSINLTLDIYIYFLNNARSFCGKQRSKQLNFLCSKQYWRMNHVNVHREFHTSKKSCKWNRSEAHCSKHWHSSSNHGVHIGIVKLSTSAPKGLTKVSIHMSRIKSTLNSVSKAIFGSQNEMVSRLAQFKPSSRIFRKVSDRGWLKHKNVKQAIESLKNYSDKSAEKNSFAEQKSYFADKEEGSDKHSLYHYAYRITTRFGESFYFLANHINSYFKNKEKMSQIKEDRQLQDKPCLEESKSISPSPDILTDRPDSGPPLNVEDKLSSSTQLPEALPVSTKQSIANFLSRPTEGVQALVGGYIGGLVPKLKSDPKSQPEEEEE... | arachidonic acid metabolic process arachidonic acid secretion cardiolipin metabolic process fatty acid metabolic process intracellular signal transduction linoleic acid metabolic process lipid homeostasis phosphatidylcholine catabolic process phosphatidylethanolamine catabolic process prostaglandin biosynthetic process... |
cristae formation diet induced thermogenesis energy homeostasis glucose metabolic process HRI-mediated signaling integrated stress response signaling lipid metabolic process mitochondrial protein processing mitochondrial respiratory chain complex assembly mitochondrion organization negative regulation of mitochondrial ... | mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial membrane; mitochondrion | lipid binding metal ion binding metalloendopeptidase activity | Rattus norvegicus | Autocatalytic cleavage Disulfide bond Hydrolase Lipid-binding Membrane Metal-binding Metalloprotease Mitochondrion Mitochondrion inner membrane Protease Reference proteome Transit peptide Transmembrane Transmembrane helix Zinc Zymogen | MNFLYGLQSA | MNFLYGLQSATRNQFLSGVNTLARRRTWTPPAGCPLASRLPAVNANWGLSTVSHCYSVILLPRNLHFCRTLKNKRSRCLSSAQSKEMGVLTYNWTVWGDASCSPNYAAIREVRSFHTSAPRQAAPVPLLMLILKPVQKLLAIIVGRGIRKWWQALPPDKKALFKDSVKRNKWRLLLGLSAFGLLFVVFYFTHLEVSPVTGRSKLLLVGKEHFRLLSDLEYEVWMEEFKNDLLPEEDPRYLTVKKVVYHLTQCNQDVPGVSEINWVVHVVHSPKVNAFVLPNGQVFVFTGLLNSVTDMHQLSFLLGHEIAHAVLGHAAEKA... | cristae formation diet induced thermogenesis energy homeostasis glucose metabolic process HRI-mediated signaling integrated stress response signaling lipid metabolic process mitochondrial protein processing mitochondrial respiratory chain complex assembly mitochondrion organization negative regulation of mitochondrial ... |
actin cytoskeleton organization cell chemotaxis fibroblast migration focal adhesion assembly phosphatidylinositol biosynthetic process phosphatidylinositol metabolic process phosphatidylinositol phosphate biosynthetic process phospholipid biosynthetic process phosphorylation protein localization to plasma membrane ruff... | cytosol; lamellipodium; mRNA cleavage and polyadenylation specificity factor complex; nuclear speck; nucleus; plasma membrane; ruffle membrane | 1-phosphatidylinositol-4-phosphate 5-kinase activity ATP binding kinase binding | Rattus norvegicus | ATP-binding Cell membrane Cell projection Cytoplasm Isopeptide bond Kinase Lipid metabolism Membrane Nucleotide-binding Nucleus Reference proteome Transferase Ubl conjugation | MASASSGPAA | MASASSGPAAAGFSPLDSGVPAGTAASGIKRGTVSEGPYASLMPVKKIGHRSVDSSGETTYKKTTSSALKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELSNSGASGSLFYVSSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHMKYDLKGSTYKRRASQKEREKTLPTFKDLDFLQDIPDGLFLDADMYSALCKTLQRDCLVLQSFKIMDYSLLMSIHNMDHAQ... | actin cytoskeleton organization cell chemotaxis fibroblast migration focal adhesion assembly phosphatidylinositol biosynthetic process phosphatidylinositol metabolic process phosphatidylinositol phosphate biosynthetic process phospholipid biosynthetic process phosphorylation protein localization to plasma membrane ruff... |
cellular response to osmotic stress intracellular signal transduction negative regulation of TORC1 signaling negative regulation of Wnt signaling pathway phosphorylation protein stabilization regulation of DNA-templated transcription transforming growth factor beta receptor signaling pathway Wnt signaling pathway | cytoplasm; nucleus | ATP binding DNA-binding transcription factor binding magnesium ion binding MAP kinase activity protein kinase activity protein serine kinase activity protein serine/threonine kinase activity SH2 domain binding ubiquitin protein ligase binding | Rattus norvegicus | ATP-binding Cytoplasm Kinase Magnesium Metal-binding Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transcription Transcription regulation Transferase Wnt signaling pathway | MSLCGTRANA | MSLCGTRANAKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPPHLHHHHHPQHHLHPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQQPYFPSPAPGQAPGPAAAAPAQVQAAAAATVKAHHHQHSHHPQQQLDIEPDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPPHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGLARVEELDESRHMTQEVVTQYYRAPEILMGSRHYSN... | cellular response to osmotic stress intracellular signal transduction negative regulation of TORC1 signaling negative regulation of Wnt signaling pathway phosphorylation protein stabilization regulation of DNA-templated transcription transforming growth factor beta receptor signaling pathway Wnt signaling pathway cytop... |
blood coagulation Factor XII activation fibrinolysis plasma kallikrein-kinin cascade positive regulation of blood coagulation positive regulation of fibrinolysis positive regulation of plasminogen activation protein autoprocessing protein processing response to misfolded protein zymogen activation | extracellular space; rough endoplasmic reticulum | calcium ion binding peptidase activity serine-type endopeptidase activity | Rattus norvegicus | Blood coagulation Disulfide bond EGF-like domain Fibrinolysis Glycoprotein Hemostasis Hydrolase Kringle Protease Reference proteome Repeat Secreted Serine protease Signal Zymogen | MTALLFLGSL | MTALLFLGSLLMSLDLTLSAPPWKSKEFKDGAGDPSVVLTVDGKLCHFPFQYHRRLYHKCIHKGQPGSRPWCATTPNFDEDQQWGYCLEPKKVKDHCSKHSPCHKGGTCVNTPNGPHCLCPEHLTGKHCQREKCFESQLLKFFHENEIWFRTGPGGVARCQCKGPQAVCKLLTSQVCRVNPCLNGGTCLLVEDHRLCHCPAGYAGPFCDLDLKATCYEDRGLSYRGQAKTTLSGAPCQRWASEATYRNMTETQALSWGLGHHAFCRNPDNDTRPWCYVWSGDRLSWDYCDLEQCQMPTLTSPVSPESHDMLKPRPPILQS... | blood coagulation Factor XII activation fibrinolysis plasma kallikrein-kinin cascade positive regulation of blood coagulation positive regulation of fibrinolysis positive regulation of plasminogen activation protein autoprocessing protein processing response to misfolded protein zymogen activation extracellular space; ... |
axon extension inner ear auditory receptor cell differentiation inner ear development inner ear morphogenesis inner ear receptor cell differentiation neuromuscular process controlling balance neuron apoptotic process positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase... | cytoplasm; nucleoplasm; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded D... | Rattus norvegicus | Activator Cytoplasm Differentiation DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MMAMNAKQPF | MMAMNAKQPFGMHPVLQEPKFSSLHSGSEAMRRVCLPAPQLQGNIFGSFDESLLARAEALAAVDIVSHGKNHPFKPDATYHTMSSVPCTSTSPTVPISHPAALTSHPHHPVHQGLEGDLLEHISPTLSVSGLGAPEHSVMPAQIHPHHLGAMGHLHQAMGMSHPHAVAPHSAMPACLSDVESDPRELEAFAERFKQRRIKLGVTQADVGAALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKPVLQAWLEEAEAAYREKNSKPELFNGSERKRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRV... | axon extension inner ear auditory receptor cell differentiation inner ear development inner ear morphogenesis inner ear receptor cell differentiation neuromuscular process controlling balance neuron apoptotic process positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase... |
positive regulation of canonical Wnt signaling pathway | cytoplasm; dendrite; extracellular region; membrane; membrane raft; neuron projection; perikaryon; plasma membrane; side of membrane; synapse | acetylcholine receptor inhibitor activity acetylcholine receptor regulator activity | Rattus norvegicus | Cell membrane Cell projection Cytoplasm Disulfide bond Glycoprotein GPI-anchor Lipoprotein Membrane Reference proteome Secreted Signal Synapse Synaptosome | MEPSPALAWL | MEPSPALAWLLLLSLVADCLKAAQSRDFTVKDIIYLHPSTTPYPGGFKCFTCEKAADNYECNRWAPDIYCPRDTRYCYTQHTMEVTGNSISVTKRCVPLEECLSTGCRDSEHEGYKICTSCCEGNICNLPLPRNDTDATFATTSPINQTNGHPHCVSVIVSCLWVWLGLTL | positive regulation of canonical Wnt signaling pathway cytoplasm; dendrite; extracellular region; membrane; membrane raft; neuron projection; perikaryon; plasma membrane; side of membrane; synapse acetylcholine receptor inhibitor activity acetylcholine receptor regulator activity Rattus norvegicus Cell membrane Cell pr... |
axon guidance basement membrane organization cell adhesion involved in heart morphogenesis fibroblast growth factor receptor signaling pathway heart morphogenesis positive regulation of synapse assembly regulation of neuron migration | cell-cell junction; endoplasmic reticulum membrane; extracellular space; focal adhesion; neuron projection; plasma membrane; synapse | chemorepellent activity fibroblast growth factor receptor binding | Rattus norvegicus | Cell adhesion Cell junction Cell membrane Developmental protein Disulfide bond Endoplasmic reticulum Extracellular matrix Glycoprotein Leucine-rich repeat Membrane Microsome Reference proteome Repeat Secreted Signal Synapse Synaptosome Transmembrane Transmembrane helix | MGLQTAKWPS | MGLQTAKWPSHGTFVLKFWLIMSLGLYSHVSKLLACPSVCRCDRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIADGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFANLRKLERLDISNNQLRMLTQGVFDHLSNLKQLTARNNPWFCDCSIKW... | axon guidance basement membrane organization cell adhesion involved in heart morphogenesis fibroblast growth factor receptor signaling pathway heart morphogenesis positive regulation of synapse assembly regulation of neuron migration cell-cell junction; endoplasmic reticulum membrane; extracellular space; focal adhesio... |
negative regulation of DNA-templated transcription negative regulation of osteoblast differentiation | nucleolus; nucleoplasm; nucleus | 2-oxoglutarate-dependent dioxygenase activity histone H3K36 demethylase activity histone H3K36me/H3K36me2 demethylase activity histone H3K4 demethylase activity histone H3K4me/H3K4me2/H3K4me3 demethylase activity iron ion binding peptidyl-histidine dioxygenase activity protein demethylase activity | Rattus norvegicus | Acetylation Chromatin regulator Dioxygenase Iron Metal-binding Nucleus Oxidoreductase Phosphoprotein Reference proteome Repressor Transcription Transcription regulation | MDELPNGNGA | MDELPNGNGAAPLKRGRGRRRRQPQPRGASVLALPLRPRKVRRHRKSAASRVAALRARALLSEDSDSNVESVRGKRERPAELPEASRSAEPRPVPVRPRPASATLPRRVEGRAALSRNLGKPAPLPGSHVDDPERPWDSPLQQVLAELNGIPSSRRRAARLFEWLLAPLPPDHFYRRLWEREAVLVRRQDHSYYEGLFSTSDLDWMLRYEDVHFGQHLDAARYIDGRRETLNPPGRALPAAAWSLYQAGCSLRLLCPQAFSPTVWQFLAVLQEQFGSMAGSNVYLTPPNSQGFAPHYDDIEAFVLQLEGRKLWRVYRPRD... | negative regulation of DNA-templated transcription negative regulation of osteoblast differentiation nucleolus; nucleoplasm; nucleus 2-oxoglutarate-dependent dioxygenase activity histone H3K36 demethylase activity histone H3K36me/H3K36me2 demethylase activity histone H3K4 demethylase activity histone H3K4me/H3K4me2/H3K... |
10-formyltetrahydrofolate metabolic process histidine biosynthetic process methionine biosynthetic process purine nucleotide biosynthetic process tetrahydrofolate interconversion | mitochondrial inner membrane; mitochondrial matrix; mitochondrion | methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase (NAD+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity | Rattus norvegicus | Alternative splicing Amino-acid biosynthesis Histidine biosynthesis Hydrolase Magnesium Membrane Methionine biosynthesis Mitochondrion Mitochondrion inner membrane Multifunctional enzyme NAD One-carbon metabolism Oxidoreductase Purine biosynthesis Reference proteome | MATRARGLSL | MATRARGLSLLRGRLGRGPARAPGVAERAWRGFGSSSRRHEAVIISGTEMAKQIRRELQQGVESWLALGNRRPHLSIILVGDNPASHTYVRNKIRAASAVGICSELIVKPKNVSQEELLDITDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWEIIKRAGIETFGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRHTPREQLKAHTQLAEIIIVAAGIPGLITADMVREGATVIDVGINYVQDPVTGKTKLVGDVDFEAVKKKASFITPVPGGVGPM... | 10-formyltetrahydrofolate metabolic process histidine biosynthetic process methionine biosynthetic process purine nucleotide biosynthetic process tetrahydrofolate interconversion mitochondrial inner membrane; mitochondrial matrix; mitochondrion methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate ... |
actin crosslink formation microtubule bundle formation negative regulation of microtubule depolymerization positive regulation of G protein-coupled receptor signaling pathway protein localization to microtubule plus-end regulation of cilium beat frequency involved in ciliary motility regulation of microtubule polymeriz... | actin filament; ciliary basal body; cytoplasm; microtubule plus-end; plasma membrane; stress fiber | actin filament binding cytoskeletal anchor activity G-protein alpha-subunit binding microtubule binding | Rattus norvegicus | Cell membrane Cell projection Cytoplasm Cytoskeleton Membrane Reference proteome | MSQHVGHGRK | MSQHVGHGRKPRTPGPPVRSIRPFKSSEQYLEVMKEDLAEWLRDLYGLDIDAANFLRVLETGLVLCRHANTVTEAALAFLAEAPERVQKIPMPQVGVFCNGAAQPGTFQARDNISNFIQWCRKEMGIQEVLMFETEDLVLRKNVKSVVLCLLELGRRAWRFGVAAPSLVYLEEEIEEELRRDLDLPSPDPPPPVPPARRPCHFHNLDQMVQSLVSHCTCPVQFSMVKISDGKYRVGDSNTLIFIRILRSHVMVRVGGGWDTLGHYLDKHDPCRCTSLSHKPGSFLKPPGPPVQHEVKVQDGPSQPQPLMTISRSQSPLPP... | actin crosslink formation microtubule bundle formation negative regulation of microtubule depolymerization positive regulation of G protein-coupled receptor signaling pathway protein localization to microtubule plus-end regulation of cilium beat frequency involved in ciliary motility regulation of microtubule polymeriz... |
cell differentiation innate immune response NAD catabolic process negative regulation of MyD88-independent toll-like receptor signaling pathway nervous system development nervous system process protein localization to mitochondrion regulation of dendrite morphogenesis regulation of neuron apoptotic process response to ... | axon; cytoplasm; dendrite; microtubule; microtubule cytoskeleton; mitochondrial outer membrane; mitochondrion; synapse | NAD(P)+ nucleosidase activity NAD+ nucleosidase activity NAD+ nucleotidase, cyclic ADP-ribose generating signaling adaptor activity | Rattus norvegicus | Cell projection Cytoplasm Differentiation Hydrolase Immunity Innate immunity Mitochondrion NAD Neurogenesis Phosphoprotein Reference proteome Repeat Synapse Transit peptide | MVLTLLFSAY | MVLTLLFSAYKLCRFFIMSGPRPGADRLTVPGPDRSGGTSPWWAAGGRGSREVSPGVGTEVQGALERSLPELQQALSELKQASAAQAVGAGLAEVFQLVEEAWLLPAVGREVAQGLCDAIRLDGGLDLLLRLLQAPELETRVQAARLLEQILVAENRDRVARIGLGVILNLSKEREPVELARSVAGILEHMFKHSEETCQRLVAAGGLDAVLYWCRRTDPALLRHCALALANCALHGGQTVQRCMVEKRAAEWLFPLAFSKEDELLRLHACLAVAVLATNKEVEREVEHSGTLALVEPLVASLDPGRFARCLVDASDTSQ... | cell differentiation innate immune response NAD catabolic process negative regulation of MyD88-independent toll-like receptor signaling pathway nervous system development nervous system process protein localization to mitochondrion regulation of dendrite morphogenesis regulation of neuron apoptotic process response to ... |
cilium assembly epithelial cell morphogenesis nitric oxide mediated signal transduction protein transport from ciliary membrane to plasma membrane | centriole; centrosome; ciliary basal body; cilium; cytoplasm; cytosol; membrane | dynein light intermediate chain binding protein dimerization activity small GTPase binding | Rattus norvegicus | Cell projection Cilium Coiled coil Cytoplasm Cytoskeleton Phosphoprotein Protein transport Reference proteome S-nitrosylation Transport | MEEPLGSPPA | MEEPLGSPPAALSALEKNVAELTVMDVYDIASLVGHEFERVIDQHGCEAIARLMPKVVRVLEILEVLVSRHHVAPELDELRLELDRLRVERMDRIEKERKHQKELELVEDVWRGEAQDLLSQIAQLQEENKQLMTNLNHKDVGFSEEELQKHEGMSERERQVMKRLKEVVDKQRDEIRAKDRELVLKNEDVEALQQQQTRLMKINHDLRHRVTVVEAQGKALIEQKVELEADLQTKEQEMGSLRAELGKLRERLQGEHSQNGEEEEAEIPPQPDGEESISDAEKAALDLKDPNRPRFTLQELRDVLHERNELKSKVFLLQ... | cilium assembly epithelial cell morphogenesis nitric oxide mediated signal transduction protein transport from ciliary membrane to plasma membrane centriole; centrosome; ciliary basal body; cilium; cytoplasm; cytosol; membrane dynein light intermediate chain binding protein dimerization activity small GTPase binding Ra... |
cell cycle DNA damage response DNA duplex unwinding double-strand break repair via homologous recombination female gamete generation male gamete generation protein localization to chromatin protein stabilization recombinational interstrand cross-link repair | chromosome; MCM complex; MCM8-MCM9 complex; nucleus | ATP binding ATP hydrolysis activity chromatin binding enzyme binding helicase activity MutLbeta complex binding MutSalpha complex binding MutSbeta complex binding single-stranded DNA binding | Rattus norvegicus | ATP-binding Cell cycle Chromosome DNA damage DNA repair DNA replication DNA-binding Helicase Hydrolase Nucleotide-binding Nucleus Phosphoprotein Reference proteome | MSGAYRGRGF | MSGAYRGRGFGRGRFQNWKRGRGGGNFSGRWRDRTDLSKAAGNHASEQASQPLLQQSTLDQFIPYKGWKLYFSEVYSNNSPLTEKIQAFEKFFTRHIDLYDKDEIERKGSILVDFKELTKDNEITNLIPDIENALRDAPEKTLACMGLAIHQVLTKDLERHAAELQAQEGLCNGGGTMVNVPHIYARVYNYEPLTHLKNIRATCYGKYISIRGTVVRVSNIKPLCTKMAFQCAACGEIQSFPLPDGKYNLPTKCPVPACRGRSFTPLRSSPLTVTMDWQLIKIQELMSDAQREAGRIPRTIECELVHDLVDSCVPGDTVT... | cell cycle DNA damage response DNA duplex unwinding double-strand break repair via homologous recombination female gamete generation male gamete generation protein localization to chromatin protein stabilization recombinational interstrand cross-link repair chromosome; MCM complex; MCM8-MCM9 complex; nucleus ATP bindin... |
3'-UTR-mediated mRNA destabilization cellular response to organic substance fibroblast growth factor receptor signaling pathway G1/S transition of mitotic cell cycle miRNA processing miRNA-mediated gene silencing by inhibition of translation negative regulation of translation neural tube closure neural tube development... | P-body | miRNA binding translation repressor activity ubiquitin protein ligase activity ubiquitin-protein transferase activity zinc ion binding | Rattus norvegicus | Acetylation Coiled coil Cytoplasm Developmental protein Metal-binding Reference proteome Repeat RNA-binding RNA-mediated gene silencing Transferase Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger | MASFPETDFQ | MASFPETDFQICLLCKEMCGSPAPLSSSSSASSSSSQTSTSSAGGGGPGAAARRLHVLPCLHAFCRPCLEAHRLPAPGGAGPAEALKLRCPVCDQKVVLAEAAGMDALPSSAFLLSNLLDAVVATADEPPPKNGRAGGGPGGAGGHSNHRHHAHHPAQRAAAPAPQPPPGPAASPGSLLLRRPHGCSSCDEGNAASSRCLDCQEHLCDNCVRAHQRVRLTKDHYIERGPPGPAAASAAQQLGLGPPFAGAPFSILSVFPERLGFCQHHDDEVLHLYCDTCSVPICRECTLGRHGGHSFAYLQDALQDSRALTIQLLADAQ... | 3'-UTR-mediated mRNA destabilization cellular response to organic substance fibroblast growth factor receptor signaling pathway G1/S transition of mitotic cell cycle miRNA processing miRNA-mediated gene silencing by inhibition of translation negative regulation of translation neural tube closure neural tube development... |
DNA damage response positive regulation of protein ubiquitination protein autoprocessing protein-DNA covalent cross-linking repair proteolysis response to UV translesion synthesis | chromatin; nuclear speck; nucleus | double-stranded DNA binding K63-linked polyubiquitin modification-dependent protein binding metal ion binding metalloendopeptidase activity polyubiquitin modification-dependent protein binding single-stranded DNA binding ubiquitin binding | Rattus norvegicus | Acetylation Autocatalytic cleavage Chromosome DNA damage DNA repair Hydrolase Isopeptide bond Metal-binding Metalloprotease Nucleus Phosphoprotein Protease Reference proteome Ubl conjugation Zinc Zinc-finger | MDEDLVVALR | MDEDLVVALRLQEEWDVQAARRAAAREPLSLVDASWELVDPTPDLQALFLQFNDRFFWGQLEAVEVKWSVRMTLCAGICTYEGRGGMCSIRLSEPLLKLRPRKDLVETLLHEMIHAYLFVTNNDKDREGHGPEFCKHMHRINQLTGANITVYHTFHDEVDEYRRHWWRCNGPCQHKQPYYGYVKRATNRAPSAHDYWWADHQKTCGGTYIKIKEPENYAKKGRGKTKAGKQPTSAVENKDKLCRGEAQPLIPFSGKGYVLGDTSTCPSAGKLNTSHMVNDTKGLSGQDHSASGLKLDSNVEVKCEQNGLPNKKPHLVTPL... | DNA damage response positive regulation of protein ubiquitination protein autoprocessing protein-DNA covalent cross-linking repair proteolysis response to UV translesion synthesis chromatin; nuclear speck; nucleus double-stranded DNA binding K63-linked polyubiquitin modification-dependent protein binding metal ion bind... |
acetate metabolic process aspartate metabolic process positive regulation of dopamine uptake involved in synaptic transmission | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; mitochondrial matrix; mitochondrial membrane; mitochondrion | aspartate N-acetyltransferase activity | Rattus norvegicus | Acyltransferase Cytoplasm Endoplasmic reticulum Membrane Microsome Mitochondrion Reference proteome Transferase Transmembrane Transmembrane helix | MHCGPPDMVC | MHCGPPDMVCETKIVATEDHEALPGAKKDALLAAAGAMWPPLPAAPGPAAAPPPAAGPQPHGGTGGAGPPEGRGVCIREFRAAEQEAARRIFYDGILERIPNTAFRGLRQHPRTQLLYALLAALCFAVTRSLLLTCLVPAGLLALRYYYSRKVILAYLECALHTDMADIEQYYMKPPGSCFWVAVLDGNVVGIVAARAHEEDNTVELLRMSVDSRFRGKGIAKALGRRVLEFAMLHNYSAVVLGTTAVKVAAHKLYESLGFRHMGASDHYVLPGMTLSLAERLFFQVRYHRYRLQLREE | acetate metabolic process aspartate metabolic process positive regulation of dopamine uptake involved in synaptic transmission cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; mitochondrial matrix; mitochondrial membrane; mitochondrion aspartate N-acetyltransferase activity Rattus no... |
actin filament organization establishment of organelle localization mitotic spindle assembly mitotic spindle assembly checkpoint signaling negative regulation of apoptotic process positive regulation of dendrite development positive regulation of double-strand break repair positive regulation of double-strand break rep... | apical cortex; cell cortex; centrosome; chromosome; cytoplasm; mitochondrion; nucleus; protein-containing complex; subcortical maternal complex | RNA binding | Rattus norvegicus | Cell cycle Chromosome Cytoplasm Cytoskeleton Developmental protein Mitochondrion Nucleus Phosphoprotein Reference proteome | MATLKTFRTL | MATLKTFRTLVQLKHKLGKAYEIVGEPRLPKWFHVEYLEDPKKMYVEPTLVEIMFGKDGEHIPHVECTLHVLIHVNVWGPEKQAEILIFGPPNFQKDVAQMLSNVAHFCRMKLMEKEALEAGVERRLMAASKATTQPTPVKVRDAATQVAPVQVRDAAIQPAPVKVRDAATQVAPVQVHEVATQPVPVQVRDAATQPVPVRVRDAATQPVPVRVRDAATQPVPVRVRDAATQPVPVRVRDAATEPVPVQVRDAATQPAPVQVRDAATQPAPVQVRDAATQPAPVQVRDAATQPAPVQVRDAATQPAPVQVRDAATQPAPV... | actin filament organization establishment of organelle localization mitotic spindle assembly mitotic spindle assembly checkpoint signaling negative regulation of apoptotic process positive regulation of dendrite development positive regulation of double-strand break repair positive regulation of double-strand break rep... |
chromosome organization deoxyribonucleoside triphosphate catabolic process ITP catabolic process nucleoside triphosphate catabolic process | cytoplasm | dITP diphosphatase activity identical protein binding ITP diphosphatase activity metal ion binding nucleoside triphosphate diphosphatase activity nucleotide binding XTP diphosphatase activity | Rattus norvegicus | Acetylation Cytoplasm Hydrolase Magnesium Manganese Metal-binding Nucleotide metabolism Nucleotide-binding Phosphoprotein Reference proteome | MAASLVGKKI | MAASLVGKKIVFVTGNAKKLEEVIQILGDKFPCTLVAQKIDLPEYQGEPDEISIQKCQEAARQVQGPVLVEDTCLCFNALGGLPGPYIKWFLQKLKPEGLYQLLAGFEDKSAYALCTFALSTGDPSQPVLLFRGKTPGQIVMPRGSRDFGWDPCFQPDGYEQTYAEMPKAEKNTISHRFRALFKLQEYFGVTDGAGDH | chromosome organization deoxyribonucleoside triphosphate catabolic process ITP catabolic process nucleoside triphosphate catabolic process cytoplasm dITP diphosphatase activity identical protein binding ITP diphosphatase activity metal ion binding nucleoside triphosphate diphosphatase activity nucleotide binding XTP di... |
chromatin organization hemopoiesis heterochromatin formation negative regulation of DNA-templated transcription regulation of megakaryocyte differentiation regulation of mitotic nuclear division | chromatin; chromatin lock complex; condensed chromosome; nucleoplasm; nucleus | chromatin binding histone binding identical protein binding methylated histone binding nucleosome binding SAM domain binding zinc ion binding | Rattus norvegicus | Chromatin regulator Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Repressor Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MEGHSDMEII | MEGHSDMEIIRAVKGSATGEINVHLVARDSAGSHPHLPTTTFIIPTNAATLGLPSTALDVSYPREPVHVGAAERVAGSEPVTATILPQLSTGPGTNSTVRLLDWTGVSAPLAGSGMRFRINEYATQNMIEIERPRSPEQRHEGGTAGREADIQHPDVHKDPQEVIPQEPSVDAGSCKCQTCGPQQSIGLDVGSSGDRCPQPFQKRSVIVENSGCTVASELIKPMKKRKHKEYQSPSEESEPEAMKQGKGKDPDREPTPGTSENEEWSRSQLVSSEKKEGWSWESYLEEQKAVTAPVSLFQDSQAVTHNKNGFKLGMKLEG... | chromatin organization hemopoiesis heterochromatin formation negative regulation of DNA-templated transcription regulation of megakaryocyte differentiation regulation of mitotic nuclear division chromatin; chromatin lock complex; condensed chromosome; nucleoplasm; nucleus chromatin binding histone binding identical pro... |
clathrin coat assembly clathrin-dependent endocytosis membrane invagination protein localization to plasma membrane synaptic vesicle endocytosis | clathrin-coated pit; clathrin-coated vesicle; cytoplasm; plasma membrane; presynaptic endocytic zone membrane | identical protein binding phosphatidylinositol binding phosphatidylinositol-4,5-bisphosphate binding phosphatidylserine binding | Rattus norvegicus | Coated pit Coiled coil Disulfide bond Endocytosis Isopeptide bond Membrane Phosphoprotein Reference proteome Ubl conjugation | MVMAHFVENF | MVMAHFVENFWGEKNNGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGTLEAVQAIQNITQALQKSKENYNAKCVEQERLKKEGATPREIEKAAVKSKKATDTYKLYVEKYALTKADFEQKMTETAQKFQDIEETHLIHIKEIIGSLSNAIKEIHLQIGQVHEEFINNMANTTIESLIQKFAESKGTGKERPGLIEFEECDPASAVEGIKPRKRKTFALPGIIKKEKDAESVECPDADSLNIPDVDE... | clathrin coat assembly clathrin-dependent endocytosis membrane invagination protein localization to plasma membrane synaptic vesicle endocytosis clathrin-coated pit; clathrin-coated vesicle; cytoplasm; plasma membrane; presynaptic endocytic zone membrane identical protein binding phosphatidylinositol binding phosphatid... |
cell division cellular response to amino acid stimulus cellular response to leucine mitotic sister chromatid segregation mitotic spindle assembly checkpoint signaling negative regulation of autophagy negative regulation of type I interferon production positive regulation of cell growth positive regulation of TORC1 sign... | centrosome; Cul3-RING ubiquitin ligase complex; cytoplasm; cytosol; lysosome; mitotic spindle; nucleus; polar microtubule | 14-3-3 protein binding ubiquitin ligase-substrate adaptor activity | Rattus norvegicus | Acetylation Cell cycle Cell division Cytoplasm Cytoskeleton Kelch repeat Lysosome Mitosis Nucleus Phosphoprotein Reference proteome Repeat Ubl conjugation pathway | MAEEQDFAQL | MAEEQDFAQLCKLSTQPSHSHCVNNTYRSTQHSQALLRGLLALRDSGILFDVVLVVEGRHIEAHRILLAASCDYFRGMFAGGLKEMEQEEVLIHGVSYNAMCQILHFIYTSELELSLSNVQETLVAACQLQIPEIIHFCCDFLMSWVDEENILDVYRLAELFDLNRLTQQLDTYILKNFVAFSRTDKYRQLPLEKVYSLLSSNRLEVSCETEVYEGALLYHYSMEQVQADQISLHEPPKLLETVRFPLMEAEVLQRLHDKLGPSPLRDTVASALMYHRNESLQPSLQGPHTELRSDFQCVVGFGGIHSTPSTILSDQAKY... | cell division cellular response to amino acid stimulus cellular response to leucine mitotic sister chromatid segregation mitotic spindle assembly checkpoint signaling negative regulation of autophagy negative regulation of type I interferon production positive regulation of cell growth positive regulation of TORC1 sign... |
adult walking behavior calcium ion transport cAMP metabolic process cellular response to leukemia inhibitory factor chemical synaptic transmission detection of light stimulus involved in visual perception gamma-aminobutyric acid secretion gamma-aminobutyric acid signaling pathway intracellular calcium ion homeostasis m... | glutamatergic synapse; nuclear speck; plasma membrane; presynapse; voltage-gated calcium channel complex | high voltage-gated calcium channel activity protein kinase binding voltage-gated calcium channel activity voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels | Rattus norvegicus | 3D-structure Alternative splicing Methylation Phosphoprotein Reference proteome SH3 domain | MSSSYAKNGA | MSSSYAKNGAADGPHSPSSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTTTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQ... | adult walking behavior calcium ion transport cAMP metabolic process cellular response to leukemia inhibitory factor chemical synaptic transmission detection of light stimulus involved in visual perception gamma-aminobutyric acid secretion gamma-aminobutyric acid signaling pathway intracellular calcium ion homeostasis m... |
epithelial cell differentiation fatty acid beta-oxidation heme metabolic process intracellular sequestering of iron ion siderophore biosynthetic process | cytoplasm | 3-hydroxybutyrate dehydrogenase activity 4-oxoproline reductase activity NAD binding oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor | Rattus norvegicus | Cytoplasm Lipid metabolism NAD Oxidoreductase Reference proteome | MGRLEGKVIV | MGRLEGKVIVLTAAAQGIGRASALAFAREGAKVIATDINEAKLQELENYPGIQTRVLDVTKKRQIDQFASEIEKIDVLFNVAGFVHHGTILDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSIKGVENRCVYSATKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARDDPKEALKAFLNRQKTGRFASAEEVALLCVYLASDESAYVTGTPVVIDGGWSL | epithelial cell differentiation fatty acid beta-oxidation heme metabolic process intracellular sequestering of iron ion siderophore biosynthetic process cytoplasm 3-hydroxybutyrate dehydrogenase activity 4-oxoproline reductase activity NAD binding oxidoreductase activity, acting on the CH-CH group of donors, NAD or NAD... |
cellular response to calcium ion negative regulation of gene expression negative regulation of non-canonical NF-kappaB signal transduction neuron projection extension positive regulation of neuron differentiation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulati... | cytoplasm; cytosol; membrane; nucleus; plasma membrane | calcium ion binding calcium-dependent phospholipid binding endopeptidase activity identical protein binding NF-kappaB binding phosphatidylserine binding | Rattus norvegicus | Acetylation Calcium Cell membrane Cytoplasm Differentiation Membrane Metal-binding Nucleus Reference proteome Repeat Repressor Transcription Transcription regulation | MAHCVTLVQL | MAHCVTLVQLSVSCDHLIDKDIGSKSDPLCVLLQDVGGAWAELCRTERVRNCSSPAFSKTLQIEYYFETVQKLRFGIYDIDNKTPELGDDDFLGGAECSLGQIVSSQTLTLPLMLKPGKPAGRGTITVSAQELKDSRVVTMEVEARNLDKKDFLGKSDPFLEFFRQGDGKWHLAYRTEVVKNNLNPTWKRFSVSLQHFCGGDLNTPIQVRCSDYDSDGSHDLIGTFHTTLAQLQAVPAEFECIHPEKQQRKKSYKNSGTVCVKTCRVETEYSFLDYVMGGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLTALW... | cellular response to calcium ion negative regulation of gene expression negative regulation of non-canonical NF-kappaB signal transduction neuron projection extension positive regulation of neuron differentiation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulati... |
cholesterol homeostasis circadian rhythm establishment of localization in cell lipid metabolic process lipid transport lipoprotein metabolic process lipoprotein transport low-density lipoprotein particle remodeling phospholipid transport plasma lipoprotein particle assembly protein secretion response to calcium ion tri... | basolateral plasma membrane; brush border membrane; cytosol; endoplasmic reticulum; Golgi apparatus; microvillus membrane; receptor complex; vesicle | apolipoprotein binding ceramide 1-phosphate transfer activity cholesterol transfer activity lipid binding lipid transporter activity phosphatidylcholine transfer activity phosphatidylethanolamine transfer activity phospholipid transfer activity phospholipid transporter activity protein heterodimerization activity prote... | Rattus norvegicus | Disulfide bond Endoplasmic reticulum Golgi apparatus Lipid transport Lipid-binding Reference proteome Signal Transport | MILLAVLFLC | MILLAVLFLCFFSSYSASVKGHTTGLSLNNERLYKLTYSTEVFLDGGKGKLQDSVGYRISSDVDVVLLWRNPDGDDDQLIQVTITAVNVENAGQQRGEKSIFKGKSTPKIVGKDNLEALRRPMLLHLVRGKVKEFYSYENEPVGIENLKRGLASLFQMQLTSGTTNEVDISGDCKVTYQAQQDKVVKIKALDTCKIERSGFTTANQVLGVTSKATSVTTYKIEDSFVTAVVAEETRAFALNFLQTVAGKIVSKQKLELKTTEAGPRMVPGKQVAGVIKAIDSKYKAIPIVGQVLQSVCKGCPSLAEHWQSIRKHLEPENL... | cholesterol homeostasis circadian rhythm establishment of localization in cell lipid metabolic process lipid transport lipoprotein metabolic process lipoprotein transport low-density lipoprotein particle remodeling phospholipid transport plasma lipoprotein particle assembly protein secretion response to calcium ion tri... |
apoptotic process cytoskeleton organization intracellular signal transduction learning locomotory behavior memory negative regulation of extrinsic apoptotic signaling pathway phosphorylation regulation of MAPK cascade | cytoplasm; cytosol; mitochondrion; nuclear membrane; nucleoplasm; synapse | ATP binding protein serine kinase activity protein serine/threonine kinase activity | Rattus norvegicus | Apoptosis ATP-binding Cytoplasm Kinase Mitochondrion Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MFGKKKKKIE | MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCITPIQLAPMKTIVRGNKSCKESSINGLLEDFDNISVTRSNSLRKESPPTPDQGAASRIQGHSEENGFITFSQYSSESDTTTDYTTEKYRDRSLYGDDLDLYYRGSHAAKQNGHAMKMKHGDAYYPEMKPLKSDLARFPVDYHTHLDSLSKASEYGDLKWDYQRASSSSPLDYSFQLTPSRTAGTSRCSKESLAYSESDWGPSFDDYDRRPKSSYLHQTSPQPAMRQRSKSGSGLQEPMMPFGASAFKTHPQGHSYNSYTYPR... | apoptotic process cytoskeleton organization intracellular signal transduction learning locomotory behavior memory negative regulation of extrinsic apoptotic signaling pathway phosphorylation regulation of MAPK cascade cytoplasm; cytosol; mitochondrion; nuclear membrane; nucleoplasm; synapse ATP binding protein serine k... |
ceramide biosynthetic process positive regulation of lipophagy regulation of fat cell apoptotic process sphinganine biosynthetic process sphingolipid biosynthetic process sphingolipid metabolic process sphingomyelin biosynthetic process sphingosine biosynthetic process | endoplasmic reticulum; endoplasmic reticulum membrane; serine C-palmitoyltransferase complex; SPOTS complex | pyridoxal phosphate binding serine C-palmitoyltransferase activity | Rattus norvegicus | Acyltransferase Coiled coil Endoplasmic reticulum Lipid metabolism Membrane Phosphoprotein Pyridoxal phosphate Reference proteome Sphingolipid metabolism Transferase Transmembrane Transmembrane helix | MATVAEQWVL | MATVAEQWVLVEMVQALYEAPAYHLILEGILILWIIRLVFSKTYKLQERSDLTAKEKEELIEEWQPEPLVPPVSRNHPALNYNIVSGPPTHNIVVNGKECVNFASFNFLGLLANPRVKAAAFASLKKYGVGTCGPRGFYGTFDVHLDLEERLAKFMKTEEAIIYSYGFSTIASAIPAYSKRGDIVFVDSAACFAIQKGLQASRSDIKLFKHNDVADLERLLKEQEIEDQKNPRKARVTRRFIVAEGLYMNTGTICPLPELVRLKYKYKARIFLEESLSFGVLGEHGRGVTEHYGISIDDIDLISANMENALASVGGFCCG... | ceramide biosynthetic process positive regulation of lipophagy regulation of fat cell apoptotic process sphinganine biosynthetic process sphingolipid biosynthetic process sphingolipid metabolic process sphingomyelin biosynthetic process sphingosine biosynthetic process endoplasmic reticulum; endoplasmic reticulum membr... |
chromosome condensation negative regulation of DNA recombination nucleosome assembly positive regulation of receptor-mediated endocytosis spermatogenesis | cell surface; chromatin; euchromatin; nucleosome; nucleus; vesicle | chromatin DNA binding DNA binding double-stranded DNA binding heparin binding nucleosomal DNA binding structural constituent of chromatin | Rattus norvegicus | Acetylation Chromosome Citrullination DNA-binding Hydroxylation Nucleus Phosphoprotein Reference proteome | MSETAPVPQP | MSETAPVPQPASVAPEKPAATKKTRKPAKAAVPRKKPAGPSVSELIVQAVSSSKERSGVSLAALKKSLAAAGYDVEKNNSRIKLGLKSLVNKGTLVQTKGTGAAGSFKLNKKAESKASTTKVTVKAKASGAAKKPKKTAGAAAKKTVKTPKKPKKPAVSKKTSSKSPKKPKVVKAKKVAKSPAKAKAVKPKAAKVKVTKPKTPAKPKKAAPKKK | chromosome condensation negative regulation of DNA recombination nucleosome assembly positive regulation of receptor-mediated endocytosis spermatogenesis cell surface; chromatin; euchromatin; nucleosome; nucleus; vesicle chromatin DNA binding DNA binding double-stranded DNA binding heparin binding nucleosomal DNA bindi... |
chorionic trophoblast cell differentiation DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest hepatocyte differentiation negative regulation of cell population proliferation negative regulation of cytokinesis negative regulation of G1/S transition of mitotic cell cycle negativ... | nucleus; RNA polymerase II transcription regulator complex | cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity DNA-binding transcription repressor activity, RNA polymerase II-specific identical protein binding RNA polymera... | Rattus norvegicus | Activator Cell cycle DNA damage DNA-binding Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation | MEVNCLTLKD | MEVNCLTLKDLISPRQTRLDFAVEDAETAQKENIFVDRSRMTPKTPMKNEPIDLSKQRIFTPERSPITPVKLVDRQPQVEPWTPTANLKMLISAASPDIRDREKKKELFRPIENKGDAFVNSLQLDVVGDSAVDDYEKRRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVNVLESLHLVSRVAKNQYGWHGRHSLPKTLRTLQRLGEEQKYEEQMACLQQKELDLMEYRFGERRKDGSPDPRDQHLLDFSESDYPSSSANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDVAAKILIEES... | chorionic trophoblast cell differentiation DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest hepatocyte differentiation negative regulation of cell population proliferation negative regulation of cytokinesis negative regulation of G1/S transition of mitotic cell cycle negativ... |
autophagosome assembly autophagosome maturation autophagosome membrane docking autophagy cellular response to glucose starvation cellular response to starvation early endosome to late endosome transport endosome to lysosome transport macroautophagy mitophagy negative regulation of protein phosphorylation phosphatidylin... | autophagosome; axoneme; cytosol; endoplasmic reticulum membrane; extrinsic component of omegasome membrane; extrinsic component of phagophore assembly site membrane; mitochondria-associated endoplasmic reticulum membrane; phagocytic vesicle; phagophore assembly site; phagophore assembly site membrane; phosphatidylinosi... | GTPase binding phosphatidylinositol 3-kinase inhibitor activity protein-membrane adaptor activity | Rattus norvegicus | Autophagy Coiled coil Cytoplasm Endoplasmic reticulum Membrane Phosphoprotein Reference proteome Ubl conjugation | MASPSGKGSW | MASPSGKGSWTPEAPGFGPRALAPDLVDSVDDAEGLYVAVERCPLCNTTRRRLTCAKCVQSGDFVYFDGRDRERFIDKKERLSQLKNKQEEFQKEVLKAMEGKRLTDQLRWKIMSCKMRIEQLKQTICKGNEEMKKNSEGLLKNKEKNQKLYSRAQRHQEKKEKIQRHNRKLGDLVEKKTSDLREHYDRLACLRRLHILELTSVIFPMDEVKTSGRDPADVSSETDSAMTSSMVSKLAEARRTTYLSGRWVCDDHNGDTSISITGPWISLPNNGDYSAYYNWVEEKKTTQGPDMEHNNPAYTISAALGYATQLVNIVSHI... | autophagosome assembly autophagosome maturation autophagosome membrane docking autophagy cellular response to glucose starvation cellular response to starvation early endosome to late endosome transport endosome to lysosome transport macroautophagy mitophagy negative regulation of protein phosphorylation phosphatidylin... |
fatty acid elongation, monounsaturated fatty acid fatty acid elongation, polyunsaturated fatty acid fatty acid elongation, saturated fatty acid sphingolipid biosynthetic process unsaturated fatty acid biosynthetic process very long-chain fatty acid biosynthetic process very long-chain fatty acid metabolic process | endoplasmic reticulum; endoplasmic reticulum membrane | acyltransferase activity, transferring groups other than amino-acyl groups fatty acid elongase activity | Rattus norvegicus | Endoplasmic reticulum Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism Membrane Reference proteome Transferase Transmembrane Transmembrane helix | MFGPRDSRVR | MFGPRDSRVRGWFLLDSYLPTFTLTIVYLLSIWLGNKYMKNRPALSLRGILTLYNLGITLLSAYMLVELVLSSWEGGYNLQCQNLDSAGEGDIRVAKVLWWYYFSKLVEFLDTIFFVLRKKTSQITFLHVYHHASMFNIWWCVLNWIPCGQSFFGPTLNSFIHILMYSYYGLSVFPSMHRYLWWKKYLTQAQLVQFVLTITHTLSAVVKPCGFPFGCLIFQSSYMMTLVILFLNFYIQTYRKKPMKKEMPEGAAGKEVKNGFPKAHSIAANGVTDKKVQ | fatty acid elongation, monounsaturated fatty acid fatty acid elongation, polyunsaturated fatty acid fatty acid elongation, saturated fatty acid sphingolipid biosynthetic process unsaturated fatty acid biosynthetic process very long-chain fatty acid biosynthetic process very long-chain fatty acid metabolic process endop... |
negative regulation of protein catabolic process ornithine metabolic process positive regulation of catalytic activity positive regulation of polyamine transmembrane transport putrescine biosynthetic process from ornithine trans-Golgi network membrane organization | axon; cis-Golgi network; cytoplasm; cytoplasmic vesicle; dendrite; endoplasmic reticulum-Golgi intermediate compartment membrane; granular vesicle; mitochondrion; nucleus; perikaryon; perinuclear region of cytoplasm; trans-Golgi network; transport vesicle | catalytic activity ornithine decarboxylase activator activity | Rattus norvegicus | Cell projection Cytoplasm Cytoplasmic vesicle Golgi apparatus Membrane Nucleus Reference proteome Transport Ubl conjugation | MAGYLSESDF | MAGYLSESDFVMVEEGFSTRDLLEELTLGASQATTGKVAAFFVADAVVRKHFCFLKYLPRVRPFYAVRCNSSLGVLKVLAELGLGFSCASKAEMELVQHIGVPASKIICANPCKQVAQIKYAAKHGVRLLSFDNEVELAKVVKSHPSAKSWGEVLTLDALGLHHTHRRVGCSLMFQASVIASVAQGYLELVCQPFHIGSGCPDPQAYAQSIADARLVFQMGAELGHTMNILDLGGGFPGLEGAKVRFEEVTSVIGKNIPFYTPPPCHVPLRTHATKKMTSSDFCCRVHVTAKEKPLFSPFLTEQTGAAPKSIVYHLDEGV... | negative regulation of protein catabolic process ornithine metabolic process positive regulation of catalytic activity positive regulation of polyamine transmembrane transport putrescine biosynthetic process from ornithine trans-Golgi network membrane organization axon; cis-Golgi network; cytoplasm; cytoplasmic vesicle... |
creatine transmembrane transport creatinine metabolic process monocarboxylic acid transport | basolateral plasma membrane; plasma membrane | creatine transmembrane transporter activity monocarboxylic acid transmembrane transporter activity uniporter activity | Rattus norvegicus | Cell membrane Membrane Reference proteome Transmembrane Transmembrane helix | MTKITRVGSA | MTKITRVGSASPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYSQTAWIHSIVDCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGLILGSFATSLKHLYLSLGVLTGLGFALCYSPAIAMVGKYFSRRKAFAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDPSGPEKSHDRDAQREDCKQASPYSPLTKEWTETRLCCSLQQGYGFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHHQAAFLMSILGVIDIVGNITFGWLTDRRCLKNYRY... | creatine transmembrane transport creatinine metabolic process monocarboxylic acid transport basolateral plasma membrane; plasma membrane creatine transmembrane transporter activity monocarboxylic acid transmembrane transporter activity uniporter activity Rattus norvegicus Cell membrane Membrane Reference proteome Trans... |
defense response to protozoan DNA damage response DNA damage response, signal transduction by p53 class mediator hematopoietic stem cell differentiation isotype switching lymphoid progenitor cell differentiation myeloid dendritic cell differentiation positive regulation of cytokine production positive regulation of tra... | cytoplasm; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded D... | Rattus norvegicus | Activator Cytoplasm Differentiation DNA-binding Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation | MPHSSDSSDS | MPHSSDSSDSSFSRSPPPGKQDSSDDVRKVQRREKNRIAAQKSRQRQTQKADTLHLESEDLEKQNAALRKEIKQLTEELKYFTSVLSSHEPLCSVLASGTPSPPEVVYSAHAFHQPHISSPRFQP | defense response to protozoan DNA damage response DNA damage response, signal transduction by p53 class mediator hematopoietic stem cell differentiation isotype switching lymphoid progenitor cell differentiation myeloid dendritic cell differentiation positive regulation of cytokine production positive regulation of tra... |
defense response to bacterium phagosome maturation potassium ion transmembrane transport regulation of intracellular pH sodium ion import across plasma membrane sodium ion transmembrane transport | early endosome; early endosome membrane; early phagosome; late endosome membrane; phagocytic vesicle membrane; plasma membrane; recycling endosome; recycling endosome membrane | potassium:proton antiporter activity sodium:proton antiporter activity | Rattus norvegicus | Antiport Cell membrane Cytoplasmic vesicle Endosome Ion transport Membrane Reference proteome Sodium Sodium transport Transmembrane Transmembrane helix Transport | MAGQLRLTSG | MAGQLRLTSGKDEDHFQHQGAVELLAFNFLLILTILTIWLFKNHRFRFLHETGGAMVYGLIMGLILRYATAPTDIDSGTVYNCGKLLFSPSTLLVNITDQVYEYKYQREINQHNISPHQGNAILEKMTFDPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCVVIGLIMYGFVKAMVHAGQLKSGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDAVAIVLTYSISIYSPKENPNAFDTAAFFQSVGNFLGIFAGSFAMGSAYAVVTALLTKFTKLREFPMLETGLFFLLS... | defense response to bacterium phagosome maturation potassium ion transmembrane transport regulation of intracellular pH sodium ion import across plasma membrane sodium ion transmembrane transport early endosome; early endosome membrane; early phagosome; late endosome membrane; phagocytic vesicle membrane; plasma membra... |
adaptive immune response B cell activation involved in immune response cell chemotaxis dendritic cell chemotaxis dendritic cell homeostasis G protein-coupled receptor signaling pathway humoral immune response leukocyte chemotaxis mature B cell differentiation involved in immune response osteoclast differentiation posit... | plasma membrane | G protein-coupled receptor activity oxysterol binding | Rattus norvegicus | Adaptive immunity Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Immunity Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MANNFTTPLA | MANNFTTPLAASHGNNCDLYAHHSTARILMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTTLYSMNLVISDILFTTALPTRIVYYALGFDWRIGDALCRITALLFYINTYAGVNFMTCLSIDRFFAVVHPLRYNKIKRIEYAKGICVFVWILVFAQTLPLLLKPMSKQEADKTTCMEYPNFEGTASLPWILLGACLLGYVLPLAIILLCYSQICCKLFRTAKQNPLTEKSGVNKKALNTIILIIGVFVLCFTPYHVAIMQHMVKTLYAPGALGCGVRHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKVMKMLK... | adaptive immune response B cell activation involved in immune response cell chemotaxis dendritic cell chemotaxis dendritic cell homeostasis G protein-coupled receptor signaling pathway humoral immune response leukocyte chemotaxis mature B cell differentiation involved in immune response osteoclast differentiation posit... |
long-term synaptic potentiation negative regulation of receptor internalization positive regulation of synapse assembly regulation of postsynaptic density assembly synapse organization | excitatory synapse; extracellular space; GABA-ergic synapse; glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; postsynaptic density membrane; postsynaptic specialization membrane; Schaffer collateral - CA1 synapse | neurexin family protein binding | Rattus norvegicus | Cell membrane Glycoprotein Leucine-rich repeat Membrane Postsynaptic cell membrane Reference proteome Repeat Signal Synapse Transmembrane Transmembrane helix | MGLHFKWPLG | MGLHFKWPLGAPMLAAIYAMSVVLKMLPALGMACPPKCRCEKLLFYCDSQGFHSVPNATDKGSLGLSLRHNHITALERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWSTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILSSLRSLTTVGLSGNLWECSPRVC... | long-term synaptic potentiation negative regulation of receptor internalization positive regulation of synapse assembly regulation of postsynaptic density assembly synapse organization excitatory synapse; extracellular space; GABA-ergic synapse; glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; postsynapti... |
chromatin remodeling male meiosis I male meiotic nuclear division mRNA processing positive regulation of gene expression regulation of DNA-templated transcription regulation of RNA splicing RNA splicing sperm DNA condensation spermatogenesis | chromatin; nucleus | histone binding histone reader activity lysine-acetylated histone binding | Rattus norvegicus | Activator Bromodomain Chromatin regulator Coiled coil Differentiation Meiosis mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome Repeat Spermatogenesis Transcription Transcription regulation | MSLPSRQMAI | MSLPSRQMAIVNPPPPEYINAKKTGRLTNQLQFLQRVVLKALWKHSFSWPFQQPVDAAKLKLPDYYTIIETPMDLSTIKKRLENRYYEKASECVGDFNTMFSNCYLYNKPGDDIVVMAQALEKLFMQKLSQMPQEEQIVGGKERMKKDIQQKTAVSSAKEQTPSKSAENVFKRQEIPAGFPDVCLSPLNMAQEAPPTCDSQTVVQITKGVKRRADTTTPTTSSAKASSESPPPLREAKPANAPVKENTVKSVLPDSQQQHRVLKTVKVTEQLKHCSEILKEMLAKKHLPYAWPFYNPVDVDALGLHNYYDIVKNPMDLGT... | chromatin remodeling male meiosis I male meiotic nuclear division mRNA processing positive regulation of gene expression regulation of DNA-templated transcription regulation of RNA splicing RNA splicing sperm DNA condensation spermatogenesis chromatin; nucleus histone binding histone reader activity lysine-acetylated h... |
establishment of localization in cell fatty acid transport intracellular iron ion homeostasis negative regulation of apoptotic process negative regulation of autophagy negative regulation of gluconeogenesis negative regulation of osteoblast differentiation negative regulation of osteoclast differentiation positive regu... | extracellular region; extracellular space | hormone activity identical protein binding | Rattus norvegicus | Disulfide bond Glycoprotein Hormone Hydroxylation Reference proteome Secreted Signal | MASTRSPGGA | MASTRSPGGARTLLACASLLAAMGLGVPESAEPVGTQARPQPPGTELPAPPAHSPPEPTIAHAHSVDPRDAWMLFVKQSDKGINSKKRSRTKARRLKLGLPGPPGPPGPQGPPGPFIPSEVLLKEFQLLLKGAVRQRESTEHCTRDLTTPASGGPSRDPVTQELESQDQGAVLALLAATLAQSPRAPRVEAAFHCRLRRDVQVERRALHELGVYYLPEVEGAFRRGPGLNLTSGQYTAPVAGFYALAATLHVALTKQPRKGPPQPRDRLRLLICIQSLCQHNASLETVMGLENSSELFTISVNGVLYLQTGHYTSVFLDN... | establishment of localization in cell fatty acid transport intracellular iron ion homeostasis negative regulation of apoptotic process negative regulation of autophagy negative regulation of gluconeogenesis negative regulation of osteoblast differentiation negative regulation of osteoclast differentiation positive regu... |
negative regulation of cell migration negative regulation of endocytosis negative regulation of response to oxidative stress regulation of neuronal synaptic plasticity regulation of neurotransmitter secretion | endoplasmic reticulum membrane; membrane; recycling endosome; synaptic vesicle membrane | calcium ion binding | Rattus norvegicus | Alternative splicing Calcium Cytoplasmic vesicle Endoplasmic reticulum Endosome Membrane Metal-binding Reference proteome Repeat Synapse Transmembrane Transmembrane helix | MEPRGAAAGE | MEPRGAAAGEPEPAVSPSFQARLWKNLQLGVGKGKGGGGGRAGGPERRTAATPTPSLPPPKTTQDVGSTGSRWSGFKKRKQVLDRVFSSSQPNLCCSSPEPLEPGGAGRAEQGSTLRRRLREHLLPVAKGSSTAAGTVGVTPPGGRSPDSAPSSSASSSLSSSPQPPPRGDRIRDEGTRRGSPEAHLCHQKSSSLPGTACLEQLLEPAPPPAEPARRPAEPQSLQKGEELDCSQKINPVETSNADVPLADPGMYQLDITLRRGQSLAARDRGGTSDPYVKFKIGRKEVFRSKIIHKNLNPVWEEKACVLIDHLREPLYIK... | negative regulation of cell migration negative regulation of endocytosis negative regulation of response to oxidative stress regulation of neuronal synaptic plasticity regulation of neurotransmitter secretion endoplasmic reticulum membrane; membrane; recycling endosome; synaptic vesicle membrane calcium ion binding Rat... |
cell division cellular response to camptothecin cellular response to xenobiotic stimulus chromosome separation DNA repair DNA replication DNA unwinding involved in DNA replication double-strand break repair via homologous recombination mitotic cell cycle mitotic DNA-templated DNA replication negative regulation of doub... | chromosome; cytoplasm; cytosol; nucleoplasm; nucleus; replication fork; transcription preinitiation complex | 3'-5' DNA helicase activity ATP binding ATP hydrolysis activity DNA helicase activity four-way junction helicase activity helicase activity nucleic acid binding RNA polymerase II complex binding | Rattus norvegicus | ATP-binding Cell cycle Cell division DNA damage DNA repair DNA replication Helicase Hydrolase Mitosis Nucleotide-binding Nucleus Phosphoprotein Reference proteome | MSARPFSTPF | MSARPFSTPFDRERRVRSTLKKVFGFDSFKTPLQESAIMAVVKGDKDVFVCMPTGAGKSLCYQLPAVLAKGITIVVSPLIALIQDQVDHLLALKVQVSSLNSKLSVQERKELLSDLERDKPRTKLLYITPEMAASASFQPTLNSLLSRNLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLAHAPCVALTATATPQVQEDVFAALHLKQPVASFKTPCFRANLFYDVQFKELIPDVYGNLRDFCLKALGQKADNGSSSGCGIVYCRTREACEQLAIELSSRGVNAKAYHAGLKASERTQVQNEWMEEKVPVIVATISF... | cell division cellular response to camptothecin cellular response to xenobiotic stimulus chromosome separation DNA repair DNA replication DNA unwinding involved in DNA replication double-strand break repair via homologous recombination mitotic cell cycle mitotic DNA-templated DNA replication negative regulation of doub... |
chondrocyte development chondroitin sulfate metabolic process embryonic digit morphogenesis endochondral ossification phosphatidylinositol phosphate biosynthetic process post-embryonic development skeletal system development | endomembrane system; trans-Golgi network membrane | 3'(2'),5'-bisphosphate nucleotidase activity 3',5'-nucleotide bisphosphate phosphatase activity 3'-nucleotidase activity metal ion binding | Rattus norvegicus | Acetylation Glycoprotein Golgi apparatus Hydrolase Magnesium Membrane Metal-binding Reference proteome Signal-anchor Transmembrane Transmembrane helix | MAPMGIRLSP | MAPMGIRLSPLGVAVFFLLGLGVLYHLYSGFLAGRFSLFGLGGEPAGGAAEVAVDGGTVDLREMLAVAVLAAERGGDEVRRVRESNVLHEKSKGKTREGAEDKMTSGDVLSNRKMFYLLKTAFPNVQINTEEHVDASDKEVIVWNRKIPEDILKEIAAPKEVPAESVTVWIDPLDATQEYTEDLRKYVTTMVCVAVNGKPVLGVIHKPFSEYTAWAMVDSGSNVKARSSYNEKTPKIIVSRSHAGMVKQVALQTFGNQTLIIPAGGAGYKVLALLDVPDMTQEKADLYIHVTYIKKWDICAGNAILKALGGHMTTLSGEE... | chondrocyte development chondroitin sulfate metabolic process embryonic digit morphogenesis endochondral ossification phosphatidylinositol phosphate biosynthetic process post-embryonic development skeletal system development endomembrane system; trans-Golgi network membrane 3'(2'),5'-bisphosphate nucleotidase activity ... |
potassium ion transmembrane transport potassium ion transport protein homooligomerization regulation of delayed rectifier potassium channel activity | plasma membrane; voltage-gated potassium channel complex | delayed rectifier potassium channel activity | Rattus norvegicus | Cell membrane Ion channel Ion transport Membrane Potassium Potassium channel Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel | MTLLPGDNSD | MTLLPGDNSDYDYSALSCASDTSFHPAFFPQRQAIKGVFYRRAQRLGPQDDLHQSISLGDRRRQIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILSVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMMEREDEEEALDSEDQESEGPSTSEGRLSRCMRRLRDMVEKPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGQCSQMCHNVFIVESVCVGWFSLEFLLRFIQAPSKFAFLRSPLTLIDLVAILPYYVTLLVDG... | potassium ion transmembrane transport potassium ion transport protein homooligomerization regulation of delayed rectifier potassium channel activity plasma membrane; voltage-gated potassium channel complex delayed rectifier potassium channel activity Rattus norvegicus Cell membrane Ion channel Ion transport Membrane Po... |
fatty acid elongation, monounsaturated fatty acid fatty acid elongation, polyunsaturated fatty acid fatty acid elongation, saturated fatty acid long-chain fatty-acyl-CoA biosynthetic process sphingolipid biosynthetic process unsaturated fatty acid biosynthetic process very long-chain fatty acid biosynthetic process | endoplasmic reticulum; endoplasmic reticulum membrane | fatty acid elongase activity | Rattus norvegicus | Acetylation Disulfide bond Endoplasmic reticulum Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism Membrane Reference proteome Transferase Transmembrane Transmembrane helix | MAFSDLTSRT | MAFSDLTSRTVRFYDNWIKDADPRVENWLLMSSPLPQTIILGLYVYFVTSLGPKLMENRKPFELKKAMITYNFFIVLFSVYMCYEFVMSGWGTGYSFRCDIVDYSQSPRAMRMVHTCWLYYFSKFIELFDTIFFVLRKKNSQVTFLHVFHHTIMPWTWWFGVKFAAGGLGTFHALLNTAVHVVMYFYYGLCAMGPAYQKYLWWKKHLTSLQLVQFVLVTVHIGQIFFMEDCNYQYPVFLYIIMSYGCIFLLLFLHFWYRAYTKGQRLPKTMENGNCKSKHH | fatty acid elongation, monounsaturated fatty acid fatty acid elongation, polyunsaturated fatty acid fatty acid elongation, saturated fatty acid long-chain fatty-acyl-CoA biosynthetic process sphingolipid biosynthetic process unsaturated fatty acid biosynthetic process very long-chain fatty acid biosynthetic process end... |
cell division contractile ring contraction division septum assembly FtsZ-dependent cytokinesis protein polymerization | cell division site; cytoplasm; cytoplasmic side of membrane | GTP binding GTPase activity | Haloferax volcanii | Cell cycle Cell division Cytoplasm GTP-binding Nucleotide-binding Reference proteome Septation | MQDIVREAME | MQDIVREAMERDEAERQTQSSLEDSDDQFGDPRIVIVGAGGAGNNTINRLYNIGVEGADTVAINTDKQHLKMIEADTKILVGKSLTQGLGAGGDPSMGERATEMAQGTIKDVLGDADLVFVTAGMGGGTGTGAAPVVAKIAKEQGAIVVGMVSTPFNVERARTVKAEEGLENLRNEADSIIVLDNNRLLDYVPNLPIGKAFSVMDQIIAETVKGISETITQPSLINLDYADMSTIMNQGGVAVMLVGETQDKNKTQEVVNDAMNHPLLDVDYRGASGGLVHITGGPDLTLKEAEGIASNITERLEAAANVIWGARIQDEY... | cell division contractile ring contraction division septum assembly FtsZ-dependent cytokinesis protein polymerization cell division site; cytoplasm; cytoplasmic side of membrane GTP binding GTPase activity Haloferax volcanii Cell cycle Cell division Cytoplasm GTP-binding Nucleotide-binding Reference proteome Septation... |
phosphate-containing compound metabolic process | cytoplasm | inorganic diphosphate phosphatase activity magnesium ion binding | Haloferax volcanii | Cytoplasm Hydrolase Magnesium Metal-binding Reference proteome | MVNLWEDMET | MVNLWEDMETGPNAPDEIYAVVECLKGERNKYEYDKDIPGVVLDRVLHSNVHYPSDYGFIPQTYYDDEDPFDVLVLVEDQTFPGCVIEARPVALMKMDDDGEQDDKVIAVPVEDPRYDHIEDLDDIPQQTLDEIDEFFATYKNLEAGKEVETLGWEDKQAAKDAIEHAMDLYEENFA | phosphate-containing compound metabolic process cytoplasm inorganic diphosphate phosphatase activity magnesium ion binding Haloferax volcanii Cytoplasm Hydrolase Magnesium Metal-binding Reference proteome MVNLWEDMET MVNLWEDMETGPNAPDEIYAVVECLKGERNKYEYDKDIPGVVLDRVLHSNVHYPSDYGFIPQTYYDDEDPFDVLVLVEDQTFPGCVIEARPVALMKMDDDGEQ... |
glyoxylate cycle tricarboxylic acid cycle | cytoplasm | malate synthase activity metal ion binding | Haloferax volcanii | 3D-structure Cytoplasm Direct protein sequencing Glyoxylate bypass Magnesium Metal-binding Reference proteome Transferase Tricarboxylic acid cycle | MTERRHDREF | MTERRHDREFVRTFFTSPTAVEGEDDSAKMLRRAAGLRGMQAPDVWVPDNEDATAPSMRDEGAENIVEVISEQGAEFPGEIHPRMVWHRDSPETRYQGFQHMLDITDPERGAVEHIHGFVIPEVGGIDDWKKADEFFTIVEHEHGLDEGSLAMSVIIESGEAELAMGDLRDEMGKPTNNLERLFLLVDGEVDYTKDMRAMTPTGELPAWPELRHNTSRGASAAGCVAVDGPYDDIRDVEGYRERMTDNQAKGMLGIWSLTPGQVVEANTSPLPPKTGSWLLDADGEEVELASEDGVEAYDGDRLSLEATDGGYELRVGGD... | glyoxylate cycle tricarboxylic acid cycle cytoplasm malate synthase activity metal ion binding Haloferax volcanii 3D-structure Cytoplasm Direct protein sequencing Glyoxylate bypass Magnesium Metal-binding Reference proteome Transferase Tricarboxylic acid cycle MTERRHDREF MTERRHDREFVRTFFTSPTAVEGEDDSAKMLRRAAGLRGMQAPDVWV... |
S-layer organization | plasma membrane | glycosyltransferase activity | Haloferax volcanii | Cell membrane Glycosyltransferase Membrane Reference proteome Transferase Transmembrane Transmembrane helix | MGRPTERRPA | MGRPTERRPAAATAAGVEVSVVLPAYNEARTIENTVRVTVETLESFLPADAFEVIVAEDGCDDETPEIADRLAAEDDRIRHYHSDDRLGRGGALERAFEAARGDTLVYFDTDLATDMRHLEELVERVRSGEYDAATGSRWMPDRVADRPRKRGVPSRAYNGLVRLFLRSDLRDHQCGFKAFSREAFEALRDDVEDNHWFWDTEMLVRAQRAGFRVAEFPVDWEPKGDTKVDLVRDILGMGSQILRTWWQLTVRPRITRRVTIVAGLLLTVLALALMTLYIDPSEVISVLGDADPALVAAAAVIYVVSWPLRGIRYREILR... | S-layer organization plasma membrane glycosyltransferase activity Haloferax volcanii Cell membrane Glycosyltransferase Membrane Reference proteome Transferase Transmembrane Transmembrane helix MGRPTERRPA MGRPTERRPAAATAAGVEVSVVLPAYNEARTIENTVRVTVETLESFLPADAFEVIVAEDGCDDETPEIADRLAAEDDRIRHYHSDDRLGRGGALERAFEAARGDTLVYFDTDLAT... |
proteasomal protein catabolic process protein unfolding | cytoplasm; proteasome-activating nucleotidase complex | ATP binding ATP hydrolysis activity | Haloferax volcanii | ATP-binding Chaperone Coiled coil Cytoplasm Nucleotide-binding Proteasome Reference proteome | MMTDTVDDVD | MMTDTVDDVDLPYDKDSASQQEKITALQERLEVLETQNEEMRDKLLDTNAENNKYQQKLERLTHENKKLKQSPLFVATVQEITDEGVIIKQHGNNQEALTEVTDEMREELEPDARVAVNNSLSIVKRLDKETDVRARVMQVEHSPDVTYEDIGGLEEQMQEVRETVEMPLDRPEMFAEVGIDPPSGVLLYGPPGTGKTMLAKAVANQTNASFIKMAGSELVHKFIGEGAKLVRDLFEVARENEPAVIFIDEIDAIASKRTDSKTSGDAEVQRTMMQLLAEMDGFDERGNIRIIAATNRFDMLDPAILRPGRFDRLIEVPK... | proteasomal protein catabolic process protein unfolding cytoplasm; proteasome-activating nucleotidase complex ATP binding ATP hydrolysis activity Haloferax volcanii ATP-binding Chaperone Coiled coil Cytoplasm Nucleotide-binding Proteasome Reference proteome MMTDTVDDVD MMTDTVDDVDLPYDKDSASQQEKITALQERLEVLETQNEEMRDKLLDTNA... |
proteasomal protein catabolic process | cytoplasm; proteasome core complex, beta-subunit complex | endopeptidase activity threonine-type endopeptidase activity | Haloferax volcanii | Autocatalytic cleavage Cytoplasm Direct protein sequencing Hydrolase Phosphoprotein Protease Proteasome Reference proteome Threonine protease Zymogen | MRTPTHDEFS | MRTPTHDEFSGRLDSLNGDRSNVFGPELGEFSNADRRADELGDKETKTGTTTVGIKTEEGVVLATDMRASMGYMVSSKDVQKVEEIHPTGALTIAGSVSAAQSLISSLRAEVRLYEARRGEDMSMQALSTLVGNFLRSGGFYVVQPILGGVDETGPHIYSIDPAGSILEEEYTVTGSGSQYALGVLEQEFEDGLSIEEAKGVATKAIRSAVERDLASGNGINIAVVTEDGVDIQRHQNFEGLE | proteasomal protein catabolic process cytoplasm; proteasome core complex, beta-subunit complex endopeptidase activity threonine-type endopeptidase activity Haloferax volcanii Autocatalytic cleavage Cytoplasm Direct protein sequencing Hydrolase Phosphoprotein Protease Proteasome Reference proteome Threonine protease Zy... |
cellulose catabolic process | extracellular region | cellulose 1,4-beta-cellobiosidase activity | Limnoria quadripunctata | 3D-structure Carbohydrate metabolism Cellulose degradation Disulfide bond Glycosidase Hydrolase Polysaccharide degradation Pyrrolidone carboxylic acid Secreted Signal | MSLAVVFLLG | MSLAVVFLLGFLAVSHGQQAGTETEEYHLPLTWERDGSSVSASVVIDSNWRWTHSTEDTTNCYDGNEWDSTLCPDADTCTENCAIDGVDQGTWGDTYGITASGSKLTLSFVTEGEYSTDIGSRVFLMADDDNYEIFNLLDKEFSFDVDASNLPCGLNGALYFVSMDEDGGTSKYSTNTAGAKYGTGYCDAQCPHDMKFIAGKANSDGWTPSDNDQNAGTGEMGACCHEMDIWEANSQAQSYTAHVCSVDGYTPCTGTDCGDNGDDRYKGVCDKDGCDYAAYRLGQHDFYGEGGTVDSGSTLTVITQFITGGGGLNEIRRI... | cellulose catabolic process extracellular region cellulose 1,4-beta-cellobiosidase activity Limnoria quadripunctata 3D-structure Carbohydrate metabolism Cellulose degradation Disulfide bond Glycosidase Hydrolase Polysaccharide degradation Pyrrolidone carboxylic acid Secreted Signal MSLAVVFLLG MSLAVVFLLGFLAVSHGQQAGTETEE... |
response to toxic substance | periplasmic space | haloalkane dehalogenase activity | Sphingobium indicum | 3D-structure Detoxification Direct protein sequencing Hydrolase Periplasm Reference proteome | MSLGAKPFGE | MSLGAKPFGEKKFIEIKGRRMAYIDEGTGDPILFQHGNPTSSYLWRNIMPHCAGLGRLIACDLIGMGDSDKLDPSGPERYAYAEHRDYLDALWEALDLGDRVVLVVHDWGSALGFDWARRHRERVQGIAYMEAIAMPIEWADFPEQDRDLFQAFRSQAGEELVLQDNVFVEQVLPGLILRPLSEAEMAAYREPFLAAGEARRPTLSWPRQIPIAGTPADVVAIARDYAGWLSESPIPKLFINAEPGALTTGRMRDFCRTWPNQTEITVAGAHFIQEDSPDEIGAAIAAFVRRLRPA | response to toxic substance periplasmic space haloalkane dehalogenase activity Sphingobium indicum 3D-structure Detoxification Direct protein sequencing Hydrolase Periplasm Reference proteome MSLGAKPFGE MSLGAKPFGEKKFIEIKGRRMAYIDEGTGDPILFQHGNPTSSYLWRNIMPHCAGLGRLIACDLIGMGDSDKLDPSGPERYAYAEHRDYLDALWEALDLGDRVVLVVHDWGSALGFD... |
oxidative phosphorylation proton transmembrane transport | plasma membrane; respirasome | electron transfer activity heme binding metal ion binding | Rhodobacter capsulatus | 3D-structure Cell inner membrane Cell membrane Direct protein sequencing Electron transport Heme Hydrogen ion transport Ion transport Iron Membrane Metal-binding Oxidoreductase Reference proteome Repeat Respiratory chain Transmembrane Transmembrane helix Transport | MSKKPTTKKE | MSKKPTTKKEVQTTGHSWDGIEELNTPLPRWWLWTFYATIVWGVAYSIAMPAWPIFASGATPGILGSSTRADVEKDIAKFAEMNKAVEDKLVATDLTAIAADPELVTYTRNAGAAVFRTWCAQCHGAGAGGNTGFPSLLDGDWLHGGSIETIYTNIKHGIRDPLDPDTLPVANMPAHLTDELLEPAQIDDVVQYVLKISGQPADEARATAGQQVFADNCVSCHGEDAKGMVEMGAPNLTDGIWLYGGDANTITTTIQLGRGGVMPSWSWAADGAKPRLSEAQIRAVASYVHSLGGGQ | oxidative phosphorylation proton transmembrane transport plasma membrane; respirasome electron transfer activity heme binding metal ion binding Rhodobacter capsulatus 3D-structure Cell inner membrane Cell membrane Direct protein sequencing Electron transport Heme Hydrogen ion transport Ion transport Iron Membrane Metal... |
cobalamin biosynthetic process cobalt ion transport | ATP-binding cassette (ABC) transporter complex | cobalt ion transmembrane transporter activity | Rhodobacter capsulatus | 3D-structure Cell inner membrane Cell membrane Cobalamin biosynthesis Cobalt Cobalt transport Direct protein sequencing Ion transport Membrane Reference proteome Transmembrane Transmembrane helix Transport | MHIMEGYLPV | MHIMEGYLPVTHAIGWSLAAGPFVVAGAVKIRKIVAERPEARMTLAASGAFAFVLSALKIPSVTGSCSHPTGTGLGAVVFGPSVMAVLGVIVLLFQALLLAHGGLTTLGANAFSMAIVGPWVAWGVYKLAGKAGASMAVAVFLAAFLGDLATYVTTSLQLALAYPDPVSGFLGAALKFGSVFALTQIPLAIAEGFLTVIVVDALAGKVDDKDKLRILAGEAR | cobalamin biosynthetic process cobalt ion transport ATP-binding cassette (ABC) transporter complex cobalt ion transmembrane transporter activity Rhodobacter capsulatus 3D-structure Cell inner membrane Cell membrane Cobalamin biosynthesis Cobalt Cobalt transport Direct protein sequencing Ion transport Membrane Reference... |
carbohydrate metabolic process | chloroplast | beta-glucosidase activity DIMBOA glucoside beta-D-glucosidase activity scopolin beta-glucosidase activity | Triticum aestivum | Chloroplast Direct protein sequencing Disulfide bond Glycosidase Hydrolase Plastid Reference proteome Transit peptide | MALLAAATLN | MALLAAATLNPTTHLSLRSRAGRNSENLWLRSAASSQKSKGRFCNLTVRAGTPSKPAEPIGPVFTKLKPWQIPKRDWFDKDFLFGASTSAYQIEGAWNEDGKGPSTWDHFCHKYPERISDGTNGDVAADSYHLYEEDVKALKDMGMKVYRFSISWSRILPNGTGEVNQAGIDYYNKLINSLISHDIVPYVTIWHWDTPQALEDKYGGFLDPQIVDDYKQFAKLCFESFGDRVKNWFTFNEPHTYCCFSYGEGIHAPGRCSPGMDCAVPEGDSLREPYTAGHHILLAHAEAVEMFRTHYNMHGDSKIGMAFDVMGYEPYQD... | carbohydrate metabolic process chloroplast beta-glucosidase activity DIMBOA glucoside beta-D-glucosidase activity scopolin beta-glucosidase activity Triticum aestivum Chloroplast Direct protein sequencing Disulfide bond Glycosidase Hydrolase Plastid Reference proteome Transit peptide MALLAAATLN MALLAAATLNPTTHLSLRSRAGRN... |
ceramide biosynthetic process ceramide metabolic process sphingomyelin catabolic process sphingomyelin metabolic process | cytoplasm; endoplasmic reticulum membrane; extracellular region; mitochondrial inner membrane; mitochondrial membrane; mitochondrion | metal ion binding sphingomyelin phosphodiesterase activity | Mus musculus | Endoplasmic reticulum Hydrolase Lipid metabolism Magnesium Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Reference proteome Signal-anchor Sphingolipid metabolism Transit peptide Transmembrane Transmembrane helix | MSLPDISRRR | MSLPDISRRRSPVPQEDWPLTPNALRPSPFPNPVLQALYSLSRVLLFPTYWSLDQLLGCWAPSVRSKSLGWFKVLAGSGVLLPLVVVGLPLALVGLALWLPLQVWRRPFCYQPPPACWVWPQPWHPPAERRRCFVFLTANLCLLPHGLAHFNNLSHSLQRAEAVGAALLDSLQSSQYRVSECSQPPPRVPGGELKATLPMGLDFVCLQEVFDLRAARRLVRVLVPNLGPVIYDVGTFGLMAGPYIKVLGSGLLLASRYPLLRATFRCFPNARREDAMASKGLLSVQAQLGIVDGHPIVGYLHCTHLHAPVEDGHIRCKQL... | ceramide biosynthetic process ceramide metabolic process sphingomyelin catabolic process sphingomyelin metabolic process cytoplasm; endoplasmic reticulum membrane; extracellular region; mitochondrial inner membrane; mitochondrial membrane; mitochondrion metal ion binding sphingomyelin phosphodiesterase activity Mus mus... |
proteolysis | extracellular region | metal ion binding metalloendopeptidase activity toxin activity | Naja atra | Calcium Complement system impairing toxin Direct protein sequencing Disulfide bond Fibrinogenolytic toxin Glycoprotein Hemostasis impairing toxin Hydrolase Metal-binding Metalloprotease Protease Secreted Signal Toxin Zinc | MIQALLVIIC | MIQALLVIICLAVFPHQGSSIILESGNVNDYEVVYPQKVPALLKGGVQNPQPETKYEDTMRYEFQVNGEPVVLHLERNKGLFSEDYTETHYAPDGREITTSPPVQDHCYYHGYIQNEADSSAVISACDGLKGHFEHQGETYFIEPLKISNSEAHAIYKDENVENEDETPEICGVTETTWESDESIEKTSQLTNTPEQDRYLQDKKYIEFYVIVDNRMYRYYNNDKPAIKIRVYEMINAVNTKFRPLKIHIALIGLEIWSNKDKFEVKPAASVTLKSFGEWRETVLLPRKRNDNAQLLTGIDFNGNTVGRAYIGSLCKTNE... | proteolysis extracellular region metal ion binding metalloendopeptidase activity toxin activity Naja atra Calcium Complement system impairing toxin Direct protein sequencing Disulfide bond Fibrinogenolytic toxin Glycoprotein Hemostasis impairing toxin Hydrolase Metal-binding Metalloprotease Protease Secreted Signal Tox... |
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