Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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adult behavior cell adhesion chemical synaptic transmission neurotransmitter secretion social behavior synapse assembly vocal learning vocalization behavior | cell projection; glutamatergic synapse; presynaptic membrane; protein-containing complex | calcium channel regulator activity metal ion binding | Mus musculus | Alternative promoter usage Calcium Cell adhesion Cell membrane Cell projection Glycoprotein Heparan sulfate Membrane Metal-binding Proteoglycan Reference proteome Repeat Signal Synapse Transmembrane Transmembrane helix | MPPGGSGQGG | MPPGGSGQGGCPRRPPALAGPLPPPPPPPPLPLLLGLLLLLGAAEGARVSSSLSTTHHVHHFHSKHGTVPIAINRMPFLTRSGHAGTTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNFDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGLKVLALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTT... | adult behavior cell adhesion chemical synaptic transmission neurotransmitter secretion social behavior synapse assembly vocal learning vocalization behavior cell projection; glutamatergic synapse; presynaptic membrane; protein-containing complex calcium channel regulator activity metal ion binding Mus musculus Alternat... |
adaptive immune response blood coagulation blood coagulation, common pathway blood coagulation, fibrin clot formation cell-matrix adhesion fibrinolysis induction of bacterial agglutination innate immune response negative regulation of endothelial cell apoptotic process negative regulation of extrinsic apoptotic signali... | blood microparticle; cell cortex; cell surface; collagen-containing extracellular matrix; endoplasmic reticulum; external side of plasma membrane; extracellular space; fibrinogen complex; platelet alpha granule; synapse | metal ion binding signaling receptor binding structural molecule activity | Mus musculus | Adaptive immunity Alternative splicing Blood coagulation Calcium Coiled coil Disulfide bond Glycoprotein Hemostasis Hydroxylation Immunity Innate immunity Metal-binding Phosphoprotein Reference proteome Secreted Signal | MLSLRVTCLI | MLSLRVTCLILSVASTVWTTDTEDKGEFLSEGGGVRGPRVVERHQSQCKDSDWPFCSDDDWNHKCPSGCRMKGLIDEANQDFTNRINKLKNSLFDFQRNNKDSNSLTRNIMEYLRGDFANANNFDNTYGQVSEDLRRRIEILRRKVIEKAQQIQALQSNVRAQLIDMKRLEVDIDIKIRSCKGSCSRAVNREINLQDYEGHQKQLQQVIAKELLPTKDRQYLPALKMSPVPDLVPGSFKSQLQEAPPEWKALTEMRQMRMELERPGKDGGSRGDSPGDSRGDSRGDFATRGPGSKAENPTNPGPGGSGYWRPGNSGSGSD... | adaptive immune response blood coagulation blood coagulation, common pathway blood coagulation, fibrin clot formation cell-matrix adhesion fibrinolysis induction of bacterial agglutination innate immune response negative regulation of endothelial cell apoptotic process negative regulation of extrinsic apoptotic signali... |
azole transmembrane transport cytidine transport nucleoside import across plasma membrane nucleoside transmembrane transport pyrimidine nucleobase transport pyrimidine-containing compound transmembrane transport uridine transport | apical plasma membrane; brush border membrane; cytosol; nuclear speck; plasma membrane | azole transmembrane transporter activity pyrimidine nucleobase transmembrane transporter activity pyrimidine- and adenosine-specific:sodium symporter activity uridine transmembrane transporter activity | Mus musculus | Cell membrane Glycoprotein Membrane Reference proteome Symport Transmembrane Transmembrane helix Transport | MADDTPRQRE | MADDTPRQRESISLTPVAHGLENMGAEFLEIMEEGQLPHRHSSLPEGGGSRSKAVWKPFSRWRSLQPTVQARSLCREHWQLFEWISKGLLSTAYIGFLIVACLLDFPRALALFVITCVVLVFLAYNLLKRLLGSKLKKCVKFQGHSCLSLWLKRGLALAAGLGVILWLSLDTAQRPEQLVSFAGICVFLVLLFAGSKHHRAVSWRAVSWGLGLQFVLGLFVIRTEPGFVAFQWLGDQIRVFLSYTEAGSSFVFGEALVKDVFAFQVLPIIVFFSCVMSVLYYLGLMQWVILKIAWLMQVTMGTSATETLSVAGNIFVSQT... | azole transmembrane transport cytidine transport nucleoside import across plasma membrane nucleoside transmembrane transport pyrimidine nucleobase transport pyrimidine-containing compound transmembrane transport uridine transport apical plasma membrane; brush border membrane; cytosol; nuclear speck; plasma membrane azo... |
convergent extension involved in axis elongation convergent extension involved in neural plate elongation embryonic placenta morphogenesis in utero embryonic development negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II regulation of cell communication regulati... | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding transcription cis-regulatory region binding transcription corepressor binding | Mus musculus | 3D-structure Alternative splicing Developmental protein DNA-binding Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Zinc Zinc-finger | MERLSQMAGR | MERLSQMAGRRAWCAEDSVPRQEEEDRTRPSKTVTFKDVAVDLTQEEWQQMKPAQRALYRDVMLETYSNLVTVGCQVTKPDVIFKLEQAEEPWVLEEEMFWRRSPEAARGRMKSFAFKDMAKDLRFEDVVIYFSLEEWECLRHSHRNLYRAVMLDNYSNLLSLSLADTKPRVVSLLEQGKEPWMVMRNETKIWHPDWVSRTEAKDSSKIKTLQEKMAKKHTCPTLEDSKTRGDREVTRELEGQQVHQEGHLRQAAVTSVERPDSVQCTAHREAHPGGKPCSSEKSQKTSLCQPPPIEREQLHSKAKASEHAQHGKVFNSC... | convergent extension involved in axis elongation convergent extension involved in neural plate elongation embryonic placenta morphogenesis in utero embryonic development negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II regulation of cell communication regulati... |
axonemal dynein complex assembly cilium movement hematopoietic progenitor cell differentiation | axonemal dynein complex; axoneme; dynein axonemal particle; motile cilium | dynein heavy chain binding dynein light chain binding | Mus musculus | Alternative splicing Cell projection Cilium Cytoplasm Cytoskeleton Flagellum Reference proteome Repeat WD repeat | MHSSPTSTRK | MHSSPTSTRKQASFAASASAQPRKSISFINPSKSSAGKGYAASNPNKLAVSRTMGFLTDMKPAEKLNVPSAKTVQVLDSKGVDVTPRPLYHPDPHAASAKPNKLLTSQEGSLGSDYISSYSLYQNTLNPSMLGQYTRSVLGSSSVSKSSISTTESMSEDLEDSSYKRDRLASFTDVRVLRSTAEAAISKEELEKTIEIILTETETLRFFDLPTVMFSTESEEAEKIIEKNKKYETLCRNRLGNDLYVERMMQTFNGAPKNKEVQCEKIILEEKGVVATTWDLYDSYNIPETLLAAKRSGYSSKGSLPAKDRDPKIQDSES... | axonemal dynein complex assembly cilium movement hematopoietic progenitor cell differentiation axonemal dynein complex; axoneme; dynein axonemal particle; motile cilium dynein heavy chain binding dynein light chain binding Mus musculus Alternative splicing Cell projection Cilium Cytoplasm Cytoskeleton Flagellum Referen... |
GABAergic neuron differentiation hypothalamus cell differentiation methylation negative regulation of transcription by RNA polymerase II neurogenesis regulation of gene expression | nucleus | chromatin binding DNA binding histone methyltransferase activity metal ion binding RNA polymerase II-specific DNA-binding transcription factor binding | Mus musculus | Alternative splicing DNA-binding Metal-binding Methyltransferase Nucleus Reference proteome Repeat S-adenosyl-L-methionine Transcription Transcription regulation Transferase Zinc Zinc-finger | MPAHVTPRTE | MPAHVTPRTEDARRGAGPSSACGCSWFCHLRPVEDPASPSVCLAAVATMHGTSRTSATSVNADCCIPAGLRLGPVPGTFKLGKYLSDRREPGPKKKVRMVRGELVDESGGSPLEWIGLIRAARNPQEQTLEAIADLPGGQIFYRALRDVQPGEELTVWYSNSLAQWFDIPTTATPTHDEKGEERYICWYCWRTFRYPNSLKAHLRFHCVLSGGGGRAFLPQEHAARPGASPVAEGLGLPPKPTVPDLTAPVQAIALRPQAPAAQLAQACGARESIKREASLAPLATSPPPGKWGTPKKGKEQPDRAHSQFLGIVGGSSGG... | GABAergic neuron differentiation hypothalamus cell differentiation methylation negative regulation of transcription by RNA polymerase II neurogenesis regulation of gene expression nucleus chromatin binding DNA binding histone methyltransferase activity metal ion binding RNA polymerase II-specific DNA-binding transcript... |
peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity | apical plasma membrane; cytosol; microvillus; microvillus membrane; nuclear speck; plasma membrane | cadherin binding protein tyrosine phosphatase activity | Mus musculus | Cell membrane Cell projection Cytoplasm Disulfide bond Glycoprotein Hydrolase Membrane Phosphoprotein Protein phosphatase Reference proteome Signal Transmembrane Transmembrane helix | MARAGGNCGV | MARAGGNCGVWRSLVLLGLYGCSVVRAAGTSVTVDRHAPASSYEFSMWVEKDGVSSSPQIPVTTAAPNPVRNLRVEGQNNISISLSWEPPDQSSLQGLTYWTQCSRHGGQTETRNTTDTSVTVDGLDPGSSYECSVWVEKDGLYSKNETLNTSTAPNPVRNLRVEGQNNISISLSWEPPDQPSLQGLTYWAQCSRHGGQTETRNTADTSVTVDGLDPGSSYECSVWVEKDGVYSTNETLNTSTAPNPVRNLRVEGQNNISISLSWEPPDQPSLQGLTYWAQCSRHGGQTETRNTTDTSITVDGLDPGSSYECSVWVEKDG... | peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity apical plasma membrane; cytosol; microvillus; microvillus membrane; nuclear speck; plasma membrane cadherin binding protein tyrosine phosphatase activity Mus musculus Cell membrane Cell projection Cytoplasm Disulfide bond Glycoprote... |
cellular aldehyde metabolic process ethanol catabolic process lipid metabolic process | cytoplasm; lipid droplet | 3-chloroallyl aldehyde dehydrogenase activity aldehyde dehydrogenase (NAD+) activity aldehyde dehydrogenase activity glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity | Mus musculus | Lipid droplet Lipid metabolism Lipoprotein Methylation NAD Oxidoreductase Prenylation Reference proteome | MSAAETGSEP | MSAAETGSEPSQGAGPSEATLHSLREAFNAGRTRPTEFRTAQLRSLGRFLQENKELLQDALAKDVGKSGFESDMSEIILCENEVDLALKNLQTWMKDEPVSTNLLTKLSSAFIRKEPFGLVLIIAPWNYPVNLMIIPLVGAIAAGNCVVLKPSEISKNTEKVLAELLPQYLDQSCFAVMLGGPEETRQLLEHKFDYIFFTGSPRVGKIVMTAAAKHLTPITLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYILCSQEMQERLVPALQNSITRFYGDNPQTSPNLGRIINQKHFKRLQGLLGCGRVAIGG... | cellular aldehyde metabolic process ethanol catabolic process lipid metabolic process cytoplasm; lipid droplet 3-chloroallyl aldehyde dehydrogenase activity aldehyde dehydrogenase (NAD+) activity aldehyde dehydrogenase activity glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity Mus musculus... |
cell fate specification cell morphogenesis embryo implantation epigenetic regulation of gene expression fertilization fibroblast growth factor receptor signaling pathway germ cell development germ-line stem cell population maintenance homeostasis of number of cells within a tissue inactivation of paternal X chromosome ... | intracellular membrane-bounded organelle; nucleoplasm; nucleus | chromatin DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific metal ion binding methyltransferase activity RNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding | Mus musculus | 3D-structure DNA-binding Metal-binding Methyltransferase Nucleus Reference proteome Repeat S-adenosyl-L-methionine Transcription Transcription regulation Transferase Zinc Zinc-finger | MALPPSGETQ | MALPPSGETQSQDKANYLPQSNPHHLTTYYAHAPGYSHFRNLATTEEEFQPWKLAAAVLESQAMAPLDAFRMTAPLLNPGLAVQSEPLYNLPWYKLSPWNRIPQFTPEVPRFLDSTEHRSSGSSNQNLVLGGGGGQISGQRWEAENLLLPSPVIASLLPDGIKSSQSISVPQTLNQEGKLPFCGFNFTEEELSFVLYGAIASPEHPTDLQHAISGILVPTESSGSNHLHKTLDKDSLQLPEGLCLMQTSFGDVPHFGVFCSDFIAKGVRFGPFRGRVVNASEVKAHRDNSRMWEIFEDGHLSHFIDGKGSGNWMSYVNCA... | cell fate specification cell morphogenesis embryo implantation epigenetic regulation of gene expression fertilization fibroblast growth factor receptor signaling pathway germ cell development germ-line stem cell population maintenance homeostasis of number of cells within a tissue inactivation of paternal X chromosome ... |
positive regulation of toll-like receptor 3 signaling pathway positive regulation of toll-like receptor 4 signaling pathway | cell junction; cytosol; early endosome; Golgi apparatus; intracellular membrane-bounded organelle; nucleolus; nucleus | 1-phosphatidylinositol binding metal ion binding | Mus musculus | Endosome Metal-binding Phosphoprotein Reference proteome Repeat WD repeat Zinc Zinc-finger | MAAEIHSRPQ | MAAEIHSRPQSSRPVLLSKIEGHQDAVTAALLIPKEDGVITASEDRTIRVWLKRDSGQYWPSIYHTMASPCSAMAYHHDSRRIFVGQDNGAVMEFHVSEDFNKMNFIKTYPAHQNRVSAIIFSLAAEWVISTGHDKCVSWMCTRSGNMLGRHFFSSWASCLQYDLDTQHAFVGDYSGQITLLKLEQNTCSVITTLKGHEGSIACLWWDPIQRLLFSGASDNSVIMWDIGGRKGRTLLLQGHHDRVQSLCYLQLTRQLVSCSADGGIAVWNMDVSREEAPQWLESDSCQKCEQPFFWNIKQMWDTKTLGLRQHHCRKCGQA... | positive regulation of toll-like receptor 3 signaling pathway positive regulation of toll-like receptor 4 signaling pathway cell junction; cytosol; early endosome; Golgi apparatus; intracellular membrane-bounded organelle; nucleolus; nucleus 1-phosphatidylinositol binding metal ion binding Mus musculus Endosome Metal-b... |
box H/ACA RNA metabolic process neural crest cell development neural crest formation nucleolus organization positive regulation of cell population proliferation positive regulation of DNA-templated transcription regulation of protein import into nucleus regulation of translation | box C/D RNP complex; box H/ACA snoRNP complex; Cajal body; cytoplasm; fibrillar center; nucleolus; nucleoplasm; small nuclear ribonucleoprotein complex | box C/D RNA binding box C/D snoRNP complex binding box H/ACA snoRNA binding box H/ACA snoRNP complex binding molecular function inhibitor activity nuclear localization sequence binding protein domain specific binding protein heterodimerization activity protein kinase inhibitor activity protein-macromolecule adaptor act... | Mus musculus | Acetylation Alternative splicing Cytoplasm Isopeptide bond Methylation Nucleus Phosphoprotein Reference proteome Repeat Ubl conjugation | MADTGLRRVV | MADTGLRRVVPSDLYPLVLRFLRDSQLSEVASKFAKATGATQQDANASSLLDIYSFWLNRSTKAPKVKLQSNGPVTKKAKKETSSSDSSEDSSEDEDKKAQGLPTQKAAAQVKRASVPQHAGKAAAKASESSSSEESSEEEEEDKKKKPVQQKAAKPQAKAVRPPAKKAESSESDSDSDSDSSSEEETPQTQKPKAAVAAKAQTKAEAKPGTPAKAQPKVANGKAAASSSSSSSSDDSEEEKKAAAPPKKTVPKKQVVAKAPVKVAAAPTQKSSSSEDSSSEEEEGQRQPMKKKAGPYSSVPPPSVPLPKKSPGTQAPKK... | box H/ACA RNA metabolic process neural crest cell development neural crest formation nucleolus organization positive regulation of cell population proliferation positive regulation of DNA-templated transcription regulation of protein import into nucleus regulation of translation box C/D RNP complex; box H/ACA snoRNP co... |
microtubule-based movement mitotic cytokinesis mitotic spindle midzone assembly positive regulation of cytokinesis | centralspindlin complex; centrosome; cytoplasm; Flemming body; intercellular bridge; kinesin complex; microtubule; midbody; mitotic spindle; nucleoplasm; nucleus; spindle | ATP binding ATP hydrolysis activity microtubule binding microtubule motor activity | Mus musculus | ATP-binding Cell cycle Cell division Coiled coil Cytoplasm Cytoskeleton Isopeptide bond Microtubule Mitosis Motor protein Nucleotide-binding Nucleus Phosphoprotein Reference proteome Ubl conjugation | MKSAKAKTVR | MKSAKAKTVRKPVIKKGSQTNLKDPVGVYCRVRPLSFPDQECCVEVINSTTLQLHTPEGYRLNRNGDYKETQYSFKRVFGTHTTQKELFDVVANPLVDDLIHGKNGLLFTYGVTGSGKTYTMTGSPGSGGLLPRCLNMIFNSIGSFQAKRYVFKSNDRNSMEIQCEVDALLERQKREALPIPKTPSSKRQADPEFADMINVQEFCKAEEVDEDSVYGVFVSYIEIYNNYIYDLLEEVQFDPIKPKLPQSKTLREDKNHNMYVAGCTEVEVKSTEEAFEVFWRGQKKRRIANTHLNRESSRSHSVFSIKLVQAPLDADGDN... | microtubule-based movement mitotic cytokinesis mitotic spindle midzone assembly positive regulation of cytokinesis centralspindlin complex; centrosome; cytoplasm; Flemming body; intercellular bridge; kinesin complex; microtubule; midbody; mitotic spindle; nucleoplasm; nucleus; spindle ATP binding ATP hydrolysis activit... |
epoxygenase P450 pathway icosanoid biosynthetic process xenobiotic metabolic process | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle | arachidonic acid 11,12-epoxygenase activity arachidonic acid 14,15-epoxygenase activity arachidonic acid epoxygenase activity heme binding iron ion binding monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one ... | Mus musculus | Acetylation Alternative splicing Endoplasmic reticulum Fatty acid metabolism Heme Iron Lipid metabolism Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Phosphoprotein Reference proteome Signal | MELLGLPTLA | MELLGLPTLALLVLVMSLSLLSVWTKMRTGGRLPPGPTPLPIIGNILQLDLKDIPASLSKLAKEYGPVYTLYFGSWPTVVLHGYDVVKEALLNQGDEFLGRGPLPIIEDSQKGHGIVFSEGERWKLLRRFSLMTLKNFGMGKRSLEERVQEEARCLVEELHKTEAQPFDPTFILACAPCNVICSILFNERFPYNDKTFLNLMDLLNKNFYQLNSIWIQMYNLWPTIMKYIPGKHREFSKRLGGVKNFILEKVKEHQESLDPANPRDYIDCFLSKIEEEKHNLKSDFNLENLAICGSNLFTAGTETTSTTLRFGLLLLVKH... | epoxygenase P450 pathway icosanoid biosynthetic process xenobiotic metabolic process cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle arachidonic acid 11,12-epoxygenase activity arachidonic acid 14,15-epoxygenase activity arachidonic acid epoxygenase activity heme binding iron ion bin... |
dosage compensation by inactivation of X chromosome in utero embryonic development mRNA alternative polyadenylation mRNA export from nucleus mRNA splice site recognition mRNA splicing, via spliceosome post-transcriptional regulation of gene expression primary follicle stage regulation of alternative mRNA splicing, via ... | nuclear body; nuclear speck; nucleoplasm; nucleus; plasma membrane | mRNA binding N6-methyladenosine-containing RNA reader activity RNA binding | Mus musculus | Alternative splicing Isopeptide bond mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome RNA-binding Ubl conjugation | MAADSREEKD | MAADSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSERMESTDTKRQKPSIHSRQLISKPLSSSVSNNKRIVSTKGKSVTEYKNEEYQRSERNKRLDADRKIRLSSSSSREPYKSQPEKTCLRKRDSERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEDYGSDHETGSSGSSEQGNNTENEEEGGEEDVEEDEEVDEDAEDDEEVDEDAEEEEEEDEEEEEDEDEDEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSA... | dosage compensation by inactivation of X chromosome in utero embryonic development mRNA alternative polyadenylation mRNA export from nucleus mRNA splice site recognition mRNA splicing, via spliceosome post-transcriptional regulation of gene expression primary follicle stage regulation of alternative mRNA splicing, via ... |
inter-male aggressive behavior kidney morphogenesis neutrophil homeostasis protein glycosylation thyroid hormone metabolic process tissue morphogenesis | Golgi membrane | acetylglucosaminyltransferase activity beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity | Mus musculus | Disulfide bond Glycoprotein Glycosyltransferase Golgi apparatus Membrane Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MKIFRCCFKY | MKIFRCCFKYTLQQKLFILLLTLWLFSLLKLLNVGRLLFPQRDIYLVEYSLSTSPFVRNRFPESGDAARDNVNCSGVYEHEPLEIGKSLEIRRRSIIDLEDGDVVAMTSDCDVYQTLRQYHEKLVSREEEDFPIAYSLVVHKDAIMVERLIRAIYNQHNLYCIHYDLKSPDTFKAAMNNLAKCFPNIFIASKLETVEYAHISRLQADWNCLSDLLKSSVQWKYVINLCGQDFPLKSNFELVTELKSLQGRNMLETVRPPSAKTERFTYHHELRQVPYDYMKLPVKTNVSKGAPPHNIQVFVGSAYFVLSRAFVKYIFNSS... | inter-male aggressive behavior kidney morphogenesis neutrophil homeostasis protein glycosylation thyroid hormone metabolic process tissue morphogenesis Golgi membrane acetylglucosaminyltransferase activity beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity Mus musculus Disulfi... |
negative regulation of dendrite development negative regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II spermatogenesis | nucleus | DNA-binding transcription factor activity metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | Isopeptide bond Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MSRRKAGRVP | MSRRKAGRVPRRVDPDTDTDIEMPDLVMDVKPDLDLRSLAQGPWIARDMPISDVKRQLQTASRPLGAPSTCAPRMPLSSKSSDRQPWTDKHPDLLTCGRCGKIFPLGAIIAFMDHKKQGCQLLQVSDPISESKELKALSCLQCGRQYTSPWKLLCHAQWDHGLCIYQTQHLDTPEAPLLGLAEVAAAMSAVAVVAPVESKPPPVSSAARRSPTCDVCKKTLSSFSNLKVHMRSHTGERPYSCDQCSYACAQSSKLNRHKKTHRQLAPGSPSTSASSRGVSPAAPPEPAAYAAAPASTLPSQTVEKAGAAATAGVQEPGAP... | negative regulation of dendrite development negative regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II spermatogenesis nucleus DNA-binding transcription factor activity metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specif... |
DNA damage response double-strand break repair double-strand break repair via homologous recombination negative regulation of double-strand break repair protein ubiquitination | cytosol; nuclear body; nucleolus; nucleoplasm; nucleus; site of double-strand break | K63-linked polyubiquitin modification-dependent protein binding metal ion binding nucleosome binding ubiquitin modification-dependent histone binding ubiquitin-protein transferase activity | Mus musculus | Chromosome DNA damage DNA repair Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Transferase Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger | MAAAGPSTRA | MAAAGPSTRASSAAAAAALSRRGRRGRCDEMAAAKAGAPGPASSPALLVLRSAPRPEESGCTGCLETPGEVAALPCSHSRCRGCASRAAGPGCRRCRPRGSGWARRRARDDGQAAAELMGERARRGQPEPCRPRRDGGAAASGPRPEPEPLAEPEFIFRTPIKLSKPGELSEEYGCLRKLRGEKLQEEKDCDDQIHKLLQEDSEMGKRKADEQKKRDEAVVLKTSLEQCPARLSDSENEEPSRGQMMQTHRSAFVSKNSSCSLAFLAGKLNTKVQRSQSCSDTVQDRVRSRLRTAPPNRAKITTITPGSTPIIGVLLSTQ... | DNA damage response double-strand break repair double-strand break repair via homologous recombination negative regulation of double-strand break repair protein ubiquitination cytosol; nuclear body; nucleolus; nucleoplasm; nucleus; site of double-strand break K63-linked polyubiquitin modification-dependent protein bind... |
aflatoxin metabolic process organic acid metabolic process phospholipid metabolic process retinoic acid catabolic process xenobiotic metabolic process | cell surface; cytoplasm; endoplasmic reticulum lumen; intracellular membrane-bounded organelle; plasma membrane | all-trans retinal binding all-trans-retinol binding heme binding iron ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen retinoic acid 4-hydroxylase activity retinoic acid... | Mus musculus | Cell membrane Endoplasmic reticulum Glycoprotein Heme Iron Lipid metabolism Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome Signal | MALLLLGVWG | MALLLLGVWGILLLLGLWGLLQGCTRSPSLAPRWPPGPRPLPFLGNLHLLGVTQQDRALMELSERYGPMFTIHLGSQKTVVLSGYEVVREALVGTGHELADRPPIPIFQHIQRGGGIFFSSGARWRAGRQFTVRTLQSLGVQQPSMVGKVLQELACLKGQLDSYGGQPLPLALLGWAPCNITFTLLFGQRFDYQDPVFVSLLSLIDQVMVLLGSPGIQLFNTFPRLGAFLRLHRPVLSKIEEVRTILRTLLETRRPPLPTGGPAQSYVEALLQQGQEDDPEDMFGEANVLACTLDMVMAGTETTAATLQWAVFLMVKHPH... | aflatoxin metabolic process organic acid metabolic process phospholipid metabolic process retinoic acid catabolic process xenobiotic metabolic process cell surface; cytoplasm; endoplasmic reticulum lumen; intracellular membrane-bounded organelle; plasma membrane all-trans retinal binding all-trans-retinol binding heme ... |
angiotensin-activated signaling pathway involved in heart process CAAX-box protein maturation cardiac muscle hypertrophy myosin filament assembly negative regulation of endoplasmic reticulum calcium ion concentration positive regulation of mitochondrial calcium ion concentration protein localization to nucleus regulati... | cytosol; endoplasmic reticulum; extracellular space; mitochondrion; nucleus | GTPase regulator activity guanyl-nucleotide exchange factor activity | Mus musculus | Acetylation Alternative splicing Cytoplasm Endoplasmic reticulum Guanine-nucleotide releasing factor Mitochondrion Nucleus Reference proteome Repeat | MDNLSDTLKK | MDNLSDTLKKLKITAADRTEGSLEGCLDCLLQALAQNNAETSEKIQGSGILQLFANLLTPQASCTAKVADIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLCGRTDPASEKLMTVFCGMLMNYSNENDSLQAQLISMGVIPTLVKLLGIHCHNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSNKEDDVAELKTASDLMVLLLLGDESMQKLFEGGKGSVFQR... | angiotensin-activated signaling pathway involved in heart process CAAX-box protein maturation cardiac muscle hypertrophy myosin filament assembly negative regulation of endoplasmic reticulum calcium ion concentration positive regulation of mitochondrial calcium ion concentration protein localization to nucleus regulati... |
defense response to bacterium defense response to virus interleukin-27-mediated signaling pathway negative regulation of viral genome replication positive regulation of interferon-beta production positive regulation of tumor necrosis factor production regulation of lactation response to bacterium response to virus RNA ... | cytoplasm; cytosol; membrane; nucleoplasm; perinuclear region of cytoplasm | 2'-5'-oligoadenylate synthetase activity ATP binding double-stranded RNA binding metal ion binding | Mus musculus | Acetylation Alternative splicing Antiviral defense ATP-binding Cytoplasm Glycoprotein Immunity Innate immunity Lipoprotein Magnesium Metal-binding Myristate Nucleotide-binding Nucleotidyltransferase Reference proteome Repeat RNA-binding Transferase | MGNWLTGNWS | MGNWLTGNWSSDRSSGYSSGWSPGGSSGVPSGPVHKLEKSIQANLTPNENCLKQIAVSSVPSQKLEGYIQENLKPNRESLKQIDQAVDAIWDLLRSQIPVKEVAKGGSYGRETALRGCSDGTLVLFMDCFQQFQDQIKYQDAYLDVIELWLKIHEKKSVKHEHALVVQVSVPGQRILLQLLPVFNPLRSNENPSSCVYVDLKKSMDQVRASPGEFSDCFTTLQQRFFKKYPQRLKDLILLVKHWYEQCQEKWKTPPPQPLLYALELLTVYAWEQGCQAEDFDMAQGVRTVLRLIQRPTELCVYWTVNYNFEDETVRNILL... | defense response to bacterium defense response to virus interleukin-27-mediated signaling pathway negative regulation of viral genome replication positive regulation of interferon-beta production positive regulation of tumor necrosis factor production regulation of lactation response to bacterium response to virus RNA ... |
cilium assembly flagellated sperm motility intracellular protein transport photoreceptor cell morphogenesis single fertilization | centriole; ciliary basal body; cytoplasm; endomembrane system; intraciliary transport particle B; pericentriolar material; sperm midpiece | GTP binding GTPase activity | Mus musculus | Alternative splicing Ciliopathy GTP-binding Nucleotide-binding Reference proteome | MAGDRNRHCE | MAGDRNRHCELEQEKYDTHENVKIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAELREFRPEIPCILVANKIDADIQMTQKNFSFAKKFSLPLYFVSAADGTNVVKLFNDAIRLAVAYKESSQDFMDEVLQELENFKLEQKEEDTSGQEQSDTTKSPSPS | cilium assembly flagellated sperm motility intracellular protein transport photoreceptor cell morphogenesis single fertilization centriole; ciliary basal body; cytoplasm; endomembrane system; intraciliary transport particle B; pericentriolar material; sperm midpiece GTP binding GTPase activity Mus musculus Alternative ... |
cytoplasmic microtubule organization endoplasmic reticulum membrane organization establishment of localization in cell heart contraction intracellular calcium ion homeostasis negative regulation of release of sequestered calcium ion into cytosol positive regulation of release of sequestered calcium ion into cytosol reg... | calcium channel complex; cytosol; junctional membrane complex; junctional sarcoplasmic reticulum membrane; membrane; nucleoplasm; plasma membrane; sarcoplasmic reticulum | signaling receptor binding | Mus musculus | Alternative splicing Disulfide bond Glycoprotein Membrane Phosphoprotein Reference proteome Sarcoplasmic reticulum Transmembrane Transmembrane helix | MTEITAEGNA | MTEITAEGNASTTTTVIDNKNGCIPKSPGKVLKRSVTEDIVTTFSSPAAWLLVIALIITWSAVAIVMFDLVDYKNFSASSIAKIGSDPLKLVNDAVEETTDWIYGFFSLLSDIISSEGDEDDEDADEDIDKGEIEEPPLKRKEIHQEKAEKEEKPEKKIQTKASHREREKGKEKLKGEKPEKTATHKEKLEKKERPETKMMAKEDKKIKTKEKTEEKAKKEMKVGKQEKVKPTAAKAKETPKTPPKARKKDDKEMPAVHEQKDQYAFCRYMIDMFVHGDLKPGQSPVMPPPSLTPSKPALSTTALEEKEKEEKKKMEKKD... | cytoplasmic microtubule organization endoplasmic reticulum membrane organization establishment of localization in cell heart contraction intracellular calcium ion homeostasis negative regulation of release of sequestered calcium ion into cytosol positive regulation of release of sequestered calcium ion into cytosol reg... |
chromatin remodeling positive regulation of transcription elongation by RNA polymerase II regulation of cold-induced thermogenesis | nucleoplasm; nucleus | NuRD complex binding | Mus musculus | Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MEPRAGCRLP | MEPRAGCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKKSGLFGLSPSTLLPLADNSSAVSCHGQAPEEGTGEVMQLETGPLHPHHKDPEKDQPPKTAVSEPPPPLIPPVPAGNLPPFPPYFEGAPFPHPLWLRNTYQQWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTVSPQEASPSPLNTPKPRRRLGSGPDSEHRKPEEPEDSAVIATAAPRRSKREKREEDRVAGERVPRSPVIKISYSTPQGKGEVVKIPSRVHGSVEPFCPQQSLQNGSQDSEVSRDVEPRGGGDRPPSGSSASI... | chromatin remodeling positive regulation of transcription elongation by RNA polymerase II regulation of cold-induced thermogenesis nucleoplasm; nucleus NuRD complex binding Mus musculus Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation MEPRAGCRLP MEPRAGCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKK... |
proteolysis regulation of apoptotic process | cytoplasm; cytosol; endoplasmic reticulum membrane; nucleolus; nucleus | cysteine-type deubiquitinase activity | Mus musculus | Alternative splicing Hydrolase Protease Reference proteome Thiol protease Ubl conjugation Ubl conjugation pathway | MVVALSFPEA | MVVALSFPEADPAMSPPSAPELHQDEAQVVEELAANGKHSLSWESPQGPGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEHSQTCCSPEGCKMCAMEAHVTQSLLHTHSGDVMKPSQNLTSAFHKRKQEDAHEFLMFTLETMHESCLQVHRQSEPTSEDSSPIHDIFGGWWRSQIKCHHCQGTSYSYDPFLDIPLDISSVQSVKQALQDTEKAEELCGENSYYCGRCRQKKPASKTLKLYSAPKVLMLVLKRFSGSMGKKLDRKVSYPEFLDLKPYLSQPTGGPLPYALYAVLVHEGATCHSGHYFCCVKAGHGKWY... | proteolysis regulation of apoptotic process cytoplasm; cytosol; endoplasmic reticulum membrane; nucleolus; nucleus cysteine-type deubiquitinase activity Mus musculus Alternative splicing Hydrolase Protease Reference proteome Thiol protease Ubl conjugation Ubl conjugation pathway MVVALSFPEA MVVALSFPEADPAMSPPSAPELHQDEAQV... |
long-chain fatty acid metabolic process | endoplasmic reticulum; sarcolemma | arachidonate-CoA ligase activity long-chain fatty acid transporter activity long-chain fatty acid-CoA ligase activity nucleotide binding oleate transmembrane transporter activity very long-chain fatty acid-CoA ligase activity | Mus musculus | Cell membrane Fatty acid metabolism Ligase Lipid metabolism Lipid transport Membrane Nucleotide-binding Reference proteome Transmembrane Transmembrane helix Transport | MLLSWLTGLG | MLLSWLTGLGAGLLSLHFLQKLLFPYFWDDFWYLLKVVRYGIQMEMYKLRGELVTVLDKFLSHTRKQPRKAFIIYEGDVYTYEDVDKRSNRIAHALLNHSSLKRGDVVALLMSNEPDFVHVWFGLAKLGCVVAFLNSNLRFDSLLHCINTCEPTAVVVGGDLLGSIEEILPSLPKHVRVWGMKDSVPEGIDSLQEKLSLASDEPVPPSHHVTSSLKSTCLYIFTSGTTGLPKAAVISQLQVLKGSVGLWAFGCTADDIIYITLPLYHSSGSLLGIGGCVELGATCVLKKKFSASQFWNDCKKYNVTVFQYIGELCRYLCK... | long-chain fatty acid metabolic process endoplasmic reticulum; sarcolemma arachidonate-CoA ligase activity long-chain fatty acid transporter activity long-chain fatty acid-CoA ligase activity nucleotide binding oleate transmembrane transporter activity very long-chain fatty acid-CoA ligase activity Mus musculus Cell me... |
auditory receptor cell development auditory receptor cell stereocilium organization detection of mechanical stimulus involved in sensory perception of sound establishment of localization in cell establishment of protein localization inner ear receptor cell differentiation sensory perception of sound | cilium; nucleoplasm; nucleus; plasma membrane; stereocilia ankle link; stereocilia ankle link complex; stereocilium; stereocilium tip; USH2 complex | identical protein binding | Mus musculus | 3D-structure Alternative splicing Cell projection Cilium Nucleus Reference proteome Repeat | MARGFTVGFD | MARGFTVGFDPLGLGELSSGSLSSVSSRGHLGSDSGSTATRYLLRKQQRLLNGPSRGIRASSPMGRVILINSPIEANSDESDIIHAVRVEKSPSGRLGFSVRGGSEHGLGIFVSKVEEGSSAERAGLCVGDKITEVNGLSLESTTMGSAVRLLTSSSCLHMMVRRMGRVPGIKFSKEKTTWVDVVNRRLVVEKCSSTPSDRSSEDGVRRIVHLYTTSDDFCLGFNIRGGKEFGLGIYVSKVDHGGLAEENGIKVGDQVLAANGVRFDDISHSQAVEVLKGQTHIMLTIKETGRYPAYKEMVSEYCWLDRLSNGVLQQLSP... | auditory receptor cell development auditory receptor cell stereocilium organization detection of mechanical stimulus involved in sensory perception of sound establishment of localization in cell establishment of protein localization inner ear receptor cell differentiation sensory perception of sound cilium; nucleoplasm... |
sensory perception of sound | extracellular space; stereocilium tip | identical protein binding | Mus musculus | Disulfide bond Glycoprotein Immunoglobulin domain Reference proteome Repeat Secreted Signal | MKMPLTWYSW | MKMPLTWYSWFLLSAWILNTGAEISITPEPAQPAEGDNVTLVVHGLSGELLAYNWYAGPTLSLTFLVASYIVSTGDETPGPAHTGREAVRPDGSLDIHGALPGHTGTYILQTLNRQFQTEVGYGHMQVYEILAPPTVMANDTALVERRDTLRLVCSSPSPAEVRWFFNGDALPVAVRLGMSPDGRMLTRHGVRREEAGAYQCEVWNPVSVSRSEPLNLTVYFGPERVAILQDSTTRTGCTIKVDFNMSLTLWCVARSCPEPEYVWAFNGKALKNGQDHLNISSMTAAHEGTYTCIAKNSKTLLSGSASVVVKLSAAAVAM... | sensory perception of sound extracellular space; stereocilium tip identical protein binding Mus musculus Disulfide bond Glycoprotein Immunoglobulin domain Reference proteome Repeat Secreted Signal MKMPLTWYSW MKMPLTWYSWFLLSAWILNTGAEISITPEPAQPAEGDNVTLVVHGLSGELLAYNWYAGPTLSLTFLVASYIVSTGDETPGPAHTGREAVRPDGSLDIHGALPGHTGTYILQT... |
actin filament organization actin nucleation muscle contraction myofibril assembly pointed-end actin filament capping positive regulation of skeletal muscle fiber development skeletal muscle fiber development skeletal muscle thin filament assembly striated muscle contraction | A band; cytoplasm; cytoskeleton; M band; myofibril; striated muscle thin filament | actin monomer binding tropomyosin binding | Mus musculus | Actin-binding Coiled coil Cytoplasm Cytoskeleton Reference proteome Ubl conjugation | MSGHSRNSEQ | MSGHSRNSEQEDTLSEELDEDELLANLSPEELKELQSEMEVMAPDPHLPVGMIQKDQTDKAPTGNFNHKSLVDYMYLQKASRRMLEDERVPVSFVQSEKNTQNQREVGDKGIKNMPQFLKEKLNSEILAKKRESNGSNNVQEAEDDDEDEEEEEEDDEDEEEEEEDEEDDEGEEDEDGEQANREKNDAKEQIHNNPGTYQQLATKTAHEQKDTSETKEKGEKKIAKLDPKKLALDTSFLKVSARPSGNQTDLDGSLRRVRQNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADESVAFALANMLREN... | actin filament organization actin nucleation muscle contraction myofibril assembly pointed-end actin filament capping positive regulation of skeletal muscle fiber development skeletal muscle fiber development skeletal muscle thin filament assembly striated muscle contraction A band; cytoplasm; cytoskeleton; M band; myo... |
cell differentiation negative regulation of DNA-binding transcription factor activity negative regulation of osteoblast differentiation negative regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | nucleus | chromatin binding DNA-binding transcription factor activity, RNA polymerase II-specific histone deacetylase binding metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding | Mus musculus | Differentiation Metal-binding Nucleus Reference proteome Repeat Repressor Transcription Transcription regulation Zinc Zinc-finger | MVDALTYDDV | MVDALTYDDVYVNFTQEEWALLNPSQKSLYKDVMLETYRNLNAVGYNWEDSNIEEHCESSRRHGRHERNHTGEKPYEGIQYGEAFVHHSSLQMRKIIHTGEKRYKCNQCDKAYSRHSILQIHKRTHSGEKPYECNQCGKAFTQHSHLKIHMVTHTGEKPYKCDQCGKAFAFHSTLQVHKRTHTGEKPYECNQCSKAFAHHCHLRVHKRIHTGEKPYKCDQCGKAFVGQNDLKRHERVHTGEKPYKCNECGKAFVCNASLRTHKTTHTGVKPYECKQCTKSFASHGQLQKHERIHTGEKPYKCDQCGKAFASHDKFQKHER... | cell differentiation negative regulation of DNA-binding transcription factor activity negative regulation of osteoblast differentiation negative regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II nucleus chromatin binding DNA-binding transcription factor activity, RNA poly... |
axonogenesis forelimb morphogenesis innervation limb development motor neuron axon guidance muscle structure development positive regulation of BMP signaling pathway protein catabolic process protein polyubiquitination | nucleus; protein-containing complex | ubiquitin protein ligase activity zinc ion binding | Mus musculus | Metal-binding Nucleus Reference proteome Transferase Ubl conjugation pathway Zinc Zinc-finger | MVLVHVGYLV | MVLVHVGYLVLPVFGSVRNRGAPFQRSQHPHATSCRHFHLGPPQPQQLAPDFPLAHPVQSQPGLSAHMAPAHQHSGTLHQSLTPLPTLQFQDVTGPSFLPQALHQQYLLQQQLLEAQHRRLVSHPRRNQDRVSVHPHRLHPSFDFGHQLQTPQPRYLAEGTDWDLSVDAGLSPAQFQVRPIPQHYQHYLATPRMHHFPRNSSSTQMVVHEIRNYPYPQLHFLALQGLNPSRHTSAVRESYEELLQLEDRLGNVTRGAVQNTIERFTFPHKYKKRRPQDSKGKKDEGEESDTDEKCTICLSMLEDGEDVRRLPCMHLFHQL... | axonogenesis forelimb morphogenesis innervation limb development motor neuron axon guidance muscle structure development positive regulation of BMP signaling pathway protein catabolic process protein polyubiquitination nucleus; protein-containing complex ubiquitin protein ligase activity zinc ion binding Mus musculus M... |
diet induced thermogenesis energy homeostasis glucose metabolic process HRI-mediated signaling integrated stress response signaling lipid metabolic process mitochondrial protein processing mitochondrial respiratory chain complex assembly negative regulation of mitochondrial fusion positive regulation of apoptotic proce... | mitochondrial inner membrane; mitochondrial membrane | metal ion binding metalloendopeptidase activity | Danio rerio | Autocatalytic cleavage Disulfide bond Hydrolase Membrane Metal-binding Metalloprotease Mitochondrion Mitochondrion inner membrane Protease Reference proteome Transit peptide Transmembrane Transmembrane helix Zinc Zymogen | MQQTCIRLVK | MQQTCIRLVKLDMLSTLTRFRTHSAIRCCAQRLFHCRPSLFISARTYFIKIDSSSLPKLKGSVSFSASCVSLGSSRLGLCSSSFKTGAPAALRAPVVFQRTRGFHTSGRRRALPALPLLWMVLKPLQKIMAIILGRSIRKWWVALPANKKQLFREWSWRRRWHFLGAGTGLLFIASLFFFTHLDESPITGRTRLLVFSRKNFRELAQFNADAFMEEFKDSLIASSDPRHKVVEQVVQILAQRNQDIAEISAVPWTVHVVDSPTMNAFVLPNGEIFVFTGMLNAVTDIHQLTFILGHEMAHALIGHAAEQASLSHVVELLS... | diet induced thermogenesis energy homeostasis glucose metabolic process HRI-mediated signaling integrated stress response signaling lipid metabolic process mitochondrial protein processing mitochondrial respiratory chain complex assembly negative regulation of mitochondrial fusion positive regulation of apoptotic proce... |
cell migration neural retina development photoreceptor cell maintenance proteolysis | cytoplasm; nucleus; photoreceptor inner segment | cysteine-type deubiquitinase activity zinc ion binding | Danio rerio | Cytoplasm Hydrolase Metal-binding Nucleus Protease Reference proteome Thiol protease Ubl conjugation pathway Zinc Zinc-finger | MRLKDPFSLK | MRLKDPFSLKTADMTKRSNKPKKPRDEDSSDEVGGLTCQHVSRAVDLSSVKKAVTGSLWSVCSDCLKERNVLEGETAGAHDILVCLKCGFQGCNQAEVQHSTKHQQAHHSDSHCITISLTTWKAWCFECKEELSTHCNKKALAQTLDFLQKQSAKATSGTSSKLIKLREEPAEYVDTQRGKSPVNSTLIPVKGINNLGNTCFFNAVMQNLSQTHMLNDLIQDVKEKGHKMKISPSTETNLGSLTVTLPSPEPLTSAMFLFLQSMKESGKGPVSPKILFNQLCQKAPRFKGYQQQDSQELLHYLLDSMRVEETKRIKAGIL... | cell migration neural retina development photoreceptor cell maintenance proteolysis cytoplasm; nucleus; photoreceptor inner segment cysteine-type deubiquitinase activity zinc ion binding Danio rerio Cytoplasm Hydrolase Metal-binding Nucleus Protease Reference proteome Thiol protease Ubl conjugation pathway Zinc Zinc-f... |
histidyl-tRNA aminoacylation mitochondrial translation regulation of vasculature development sprouting angiogenesis | cytoplasm; cytosol; mitochondrion | ATP binding histidine-tRNA ligase activity identical protein binding RNA binding | Danio rerio | Alternative splicing Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Ligase Mitochondrion Nucleotide-binding Protein biosynthesis Reference proteome | MADKAQLQEA | MADKAQLQEAIKTQGEVVRKLKSEKASKEQIDEEVARLLQLKAQLGGDEGKHVFVLKTAKGTRDYNPKQMAIREKVFNIIINCFKRHGAETIDSPVFELKETLTGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKITNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGQYDAMIPDAECLKLVYEILSELDLGDFRIKVNDRRILDGMFAICGVPDEKFRTICSTVDKLDKLAWEEVKKEMVNEKGLSEEVADRIRDYVSMQGGKDLAERLLQDPKLSQSKQACAGITDMKLLFSYLELFQITDKVVF... | histidyl-tRNA aminoacylation mitochondrial translation regulation of vasculature development sprouting angiogenesis cytoplasm; cytosol; mitochondrion ATP binding histidine-tRNA ligase activity identical protein binding RNA binding Danio rerio Alternative splicing Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Ligase ... |
calcium-mediated signaling cell chemotaxis chemokine-mediated signaling pathway immune response innate immune response leukocyte migration involved in immune response macrophage activation involved in immune response macrophage chemotaxis positive regulation of cytosolic calcium ion concentration response to bacterium | external side of plasma membrane | C-C chemokine binding C-C chemokine receptor activity | Danio rerio | Cell membrane Chemotaxis Disulfide bond G-protein coupled receptor Glycoprotein Immunity Innate immunity Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MDNSTTAAEV | MDNSTTAAEVSAPTDYDYNSTSYDDDNPYAAPCSLTETWNFLGRFAPVAYILVFILALVGNILVLCVIRRYRQSRHSPCSFSLTDTFLLHLAVSDLLLAATLPFFAVEWISEWVFGKVMCKITGALFSLNVYCGVLFLACISFDRYLAIVHAINISWRRKTCHAQLACAFIWVICLGLSMVDMHFRDLVEIPGMNRMVCQIVYSEQYSKQWQIGMQLVSMVLGFILPLLVMLYCYLHIFKALCHATRRQKRRSLRLIISLVIVFVISWAPYNALRMTDSLQMLGVIVKSCALNNVLDVGILVTESLGLAHCALNPLLYGL... | calcium-mediated signaling cell chemotaxis chemokine-mediated signaling pathway immune response innate immune response leukocyte migration involved in immune response macrophage activation involved in immune response macrophage chemotaxis positive regulation of cytosolic calcium ion concentration response to bacterium ... |
ergosterol biosynthetic process methylation | endoplasmic reticulum membrane | heme binding iron ion binding methyltransferase activity oxidoreductase activity sterol 14-demethylase activity | Aspergillus fumigatus | 3D-structure Endoplasmic reticulum Heme Iron Lipid biosynthesis Lipid metabolism Membrane Metal-binding Methyltransferase Monooxygenase Oxidoreductase Reference proteome Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism Transferase Transmembrane Transmembrane helix | MGLIAFILDG | MGLIAFILDGICKHCSTQSTWVLVGIGLLSILAVSVIINVLQQLLFKNPHEPPVVFHWFPFIGSTISYGIDPYKFFFDCRAKYGDIFTFILLGKKTTVYLGTKGNDFILNGKLRDVCAEEVYSPLTTPVFGRHVVYDCPNAKLMEQKKFVKYGLTSDALRSYVPLITDEVESFVKNSPAFQGHKGVFDVCKTIAEITIYTASRSLQGKEVRSKFDSTFAELYHNLDMGFAPINFMLPWAPLPHNRKRDAAQRKLTETYMEIIKARRQAGSKKDSEDMVWNLMSCVYKNGTPVPDEEIAHMMIALLMAGQHSSSSTASWIV... | ergosterol biosynthetic process methylation endoplasmic reticulum membrane heme binding iron ion binding methyltransferase activity oxidoreductase activity sterol 14-demethylase activity Aspergillus fumigatus 3D-structure Endoplasmic reticulum Heme Iron Lipid biosynthesis Lipid metabolism Membrane Metal-binding Methyl... |
lipopolysaccharide core region biosynthetic process | plasma membrane | Kdo transferase activity | Chlamydophila psittaci | Cell inner membrane Cell membrane Lipopolysaccharide biosynthesis Membrane Signal-anchor Transferase Transmembrane Transmembrane helix | MIKGRRTKLH | MIKGRRTKLHTFLYDCFLIFAFMVGLPRILYKRFVHGKYTKSLGIRFGFKKPEVPGTGPVAWFHGASVGETALLLPLLKRFMKEYPEWRCVVTSCTESGHENAHRLFGPLGVTTFILPLDLSIIIKPVVRAISPSLLVFSEGDCWLNFIEEAKRLGATAVIINGKLSANSCKRFTILKRFGRNYFSPVDGFLLQDEQHKARFLQLGVDKEKIQVTGNIKTYTETLSENNQRDYWREKLQLAQDTELLVLGSVHPKDVEVWLPVVRELRRNLKVLWVPRHIERSKELEALLSKENISYGLWSKEATFAQHDAIIVDAIGWL... | lipopolysaccharide core region biosynthetic process plasma membrane Kdo transferase activity Chlamydophila psittaci Cell inner membrane Cell membrane Lipopolysaccharide biosynthesis Membrane Signal-anchor Transferase Transmembrane Transmembrane helix MIKGRRTKLH MIKGRRTKLHTFLYDCFLIFAFMVGLPRILYKRFVHGKYTKSLGIRFGFKKPEVPGT... |
malate metabolic process NADH metabolic process tricarboxylic acid cycle | cytoplasm | L-malate dehydrogenase activity NAD binding protein homodimerization activity | Taenia solium | Cytoplasm Direct protein sequencing NAD Oxidoreductase Tricarboxylic acid cycle | MPGPLRVLIT | MPGPLRVLITGAAGQIAYNLSNMVANGNLFGKDQKIILHLLDIPEAKTVLEGVVMELQDCAFTVLEGIVPTHCLKEAFTDIDVALMVGAMPRKQGMERRDLLSSNVKIFKDQGEALEKYAKKTVKVLVVGNPANTNCLIMSKYAPSIPKENFTALSRLDHNRAIYQVAAKVGVPSECVKNVCIWGNHSNKQFPDLAHAVVTKGGKQHPAKELINDEKWVKEVFTPCVQNRGAAVIGLRKLSSAASAAKAIVDQMHDWWFGTKEGEWVSMSVYSTGEHYGAPKDIYFSFPVTIKNGHYKVVDGLAMDEWGKGLFKITADEL... | malate metabolic process NADH metabolic process tricarboxylic acid cycle cytoplasm L-malate dehydrogenase activity NAD binding protein homodimerization activity Taenia solium Cytoplasm Direct protein sequencing NAD Oxidoreductase Tricarboxylic acid cycle MPGPLRVLIT MPGPLRVLITGAAGQIAYNLSNMVANGNLFGKDQKIILHLLDIPEAKTVLEGVV... |
diterpenoid biosynthetic process green leaf volatile biosynthetic process monoterpene biosynthetic process monoterpenoid biosynthetic process response to jasmonic acid | chloroplast | lyase activity magnesium ion binding terpene synthase activity | Picea sitchensis | Chloroplast Lyase Magnesium Manganese Metal-binding Plastid Transit peptide | MSVISIVPLA | MSVISIVPLASKPCLYKSFISSTHEPKALRRPISTVGLCRRAKSVTASMSMSSSTALSDDGVQRRIGNHHSNLWDDNFIQSLSSPYGASSYAERAERLIGEVKEIFNRISMANGELVSHVDDLLQHLSMVDNVERLGIDRHFQTEIKVSLDYVYSYWSEKGIGPGRDIVCADLNTTALGFRLLRLHGYTMFPDVFEQFKDQMGRIACSTNQTERQISSILNLFRASLIAFPWEKVMEEAEIFSTAYLKEALQTIPVSSLSREIQYVLDYRWHSDLPRLETRTYIDILRENATNETLDMKTEKLLELAKVEFNIFNSLQQN... | diterpenoid biosynthetic process green leaf volatile biosynthetic process monoterpene biosynthetic process monoterpenoid biosynthetic process response to jasmonic acid chloroplast lyase activity magnesium ion binding terpene synthase activity Picea sitchensis Chloroplast Lyase Magnesium Manganese Metal-binding Plastid... |
negative regulation of mitotic nuclear division positive regulation of protein autophosphorylation protein transport signal transduction | cytoplasm; cytosol; endosome; endosome membrane; Golgi stack; membrane | clathrin binding phosphatidylinositol binding protein kinase activator activity protein kinase binding SH3 domain binding ubiquitin binding | Rattus norvegicus | Cytoplasm Endosome Golgi apparatus Membrane Phosphoprotein Protein transport Reference proteome SH3-binding Transport | MAFGKSHRDP | MAFGKSHRDPYATSLGHLIEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKEIQLSLSLIDMCMQNCGPSFQSLIVKKEFVKDTLVKLLNPRYTLPLETQNRILSFIKMWSQGFPGGVDVSEVKEVYLDLLKKGVQFPPLDGEPETKQEAGQISPSRPTSVPTAPALSSIIAPKNPTISLVPEQIGKLHSELDMVKMNVKVMTAILMENTPGSENHEDIELLRKLYKTGREMQERIMDLLVVVENEDVTVELIQVNEDLNNAILGYERFTRNQQRLLEQKRNPTEANQTSSEPSAPSCDLLNLG... | negative regulation of mitotic nuclear division positive regulation of protein autophosphorylation protein transport signal transduction cytoplasm; cytosol; endosome; endosome membrane; Golgi stack; membrane clathrin binding phosphatidylinositol binding protein kinase activator activity protein kinase binding SH3 domai... |
cell differentiation cellular response to platelet-derived growth factor stimulus cellular response to retinoic acid cellular response to transforming growth factor beta stimulus innate immune response phosphorylation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of transcription by RNA p... | actin filament; centrosome; cytosol; extrinsic component of cytoplasmic side of plasma membrane; glutamatergic synapse; Golgi apparatus; plasma membrane; postsynaptic specialization, intracellular component | ATP binding enzyme binding epidermal growth factor receptor binding non-membrane spanning protein tyrosine kinase activity phosphotyrosine residue binding protein tyrosine kinase activity signaling receptor binding transmembrane transporter binding | Rattus norvegicus | ATP-binding Cell membrane Cytoplasm Cytoskeleton Kinase Lipoprotein Membrane Myristate Nucleotide-binding Palmitate Phosphoprotein Reference proteome SH2 domain SH3 domain Transferase Tyrosine-protein kinase | MGCIKSKENK | MGCIKSKENKSPAIKYTPENPTEPVNTSAGHYGVEHATAATTSSTKGASANFNSLSMTPFGGSSGVTPFGGASSSFSVVPSSYPTSLTGGVTIFVALYDYEARTTEDLSFKKGERFQIINNTEGDWWEARSIATGKNGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEVRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEHADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQEAQ... | cell differentiation cellular response to platelet-derived growth factor stimulus cellular response to retinoic acid cellular response to transforming growth factor beta stimulus innate immune response phosphorylation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of transcription by RNA p... |
cell cycle comprising mitosis without cytokinesis chorionic trophoblast cell differentiation fibroblast proliferation hepatocyte differentiation negative regulation of cytokinesis negative regulation of transcription by RNA polymerase II placenta development positive regulation of DNA endoreduplication positive regulat... | nucleus; RNA polymerase II transcription regulator complex | cis-regulatory region sequence-specific DNA binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity DNA-binding transcription repressor activity, RNA polymerase II-specific identical protein binding ... | Rattus norvegicus | Activator Alternative splicing Cell cycle DNA-binding Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation | MENQKENLFS | MENQKENLFSEPHKRGLVKSPLQESSKANVVLAEIQPDLGPLTTPTKPKEVSQGEPWTPTANLKMLISAVSPEIRSRDQKRGLSDNRSGLPEARDCLHEPQAKTNEKSQPSRKEKSLGLLCHKFLARYPKYPNPAVNNDICLDEVAEELDVERRRIYDIVNVLESLHMVSRLAKNRYTWHGRHNLTKTLGTLKSVGEENKYAEQIMMIKRKEHEQEFDFIKSCGLEDHHVIKSTAGQNGHSDMCFVELPGVEFRAASANSRKDKSLRVMSQKFVMLFLVSTPQIVSLEIAAKILIGEDHVEDLDKSKFKTKIRRLYDIAN... | cell cycle comprising mitosis without cytokinesis chorionic trophoblast cell differentiation fibroblast proliferation hepatocyte differentiation negative regulation of cytokinesis negative regulation of transcription by RNA polymerase II placenta development positive regulation of DNA endoreduplication positive regulat... |
carnitine metabolic process fatty acid metabolic process regulation of postsynaptic membrane neurotransmitter receptor levels | AMPA glutamate receptor complex; axon; dendrite; endoplasmic reticulum; endoplasmic reticulum membrane; glutamatergic synapse; mitochondrion; postsynapse | carnitine O-palmitoyltransferase activity palmitoyl-(protein) hydrolase activity | Rattus norvegicus | Acyltransferase Cell projection Endoplasmic reticulum Fatty acid metabolism Hydrolase Lipid metabolism Membrane Reference proteome Synapse Transferase Transmembrane Transmembrane helix | MAEAHQASSL | MAEAHQASSLLSSLSSDGAEVELSSSVWQEIYLSALRSWKRNLWRVWNDFLAGVVPATPLSWLFLFSTIQLACLLQLDPSLGLMEKIKELLPDWGGQHHQLQGLLAAAVFASCLWGTLIFTLHVALRLLLSHHGWLLEPHGTMSSPTKTWLALVRIFSGRHPRLFSFQRALPRQPVPGAQETVRKYLESMRPVLRDDAFDSVVALANDFLRLQAPRLQLYLQLKSWCASNYVSDWWEEFVYLRSRGSLVNSTYYMMDFLYVTPTPLQAARAGNAVHTLLLYRHLLNRQEIPPTLLMGMRPLCSAQYERMFNTTRIPGVEK... | carnitine metabolic process fatty acid metabolic process regulation of postsynaptic membrane neurotransmitter receptor levels AMPA glutamate receptor complex; axon; dendrite; endoplasmic reticulum; endoplasmic reticulum membrane; glutamatergic synapse; mitochondrion; postsynapse carnitine O-palmitoyltransferase activit... |
cellular response to amino acid starvation circadian rhythm mRNA processing negative regulation of DNA-templated transcription negative regulation of mRNA splicing, via spliceosome positive regulation of translation regulation of alternative mRNA splicing, via spliceosome regulation of RNA splicing response to peptide | chromatin; cytoplasm; nucleoplasm; nucleus; perinuclear region of cytoplasm; pronucleus; ribonucleoprotein complex; ribonucleoprotein granule; synapse | mRNA 3'-UTR binding mRNA binding mRNA CDS binding pre-mRNA intronic binding RNA binding transcription cis-regulatory region binding | Rattus norvegicus | 3D-structure Acetylation Alternative splicing Cytoplasm Isopeptide bond Methylation Nucleus Phosphoprotein Reference proteome Repeat Ribonucleoprotein RNA-binding Ubl conjugation | MSRRLLPRAE | MSRRLLPRAEKRRRRLEQRQQPDEQLRRAGAMVKMAAAGGGGGGGRYYGGGNEGGRAPKRLKTENAGDQHGGGGGGGSGAAGGGGGENYDDPHKTPASPVVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQALVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSRSVNSVLLFTILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPNLSGQGDPGSNPNKRQRQPPLLGDHPAEYGEGRGF... | cellular response to amino acid starvation circadian rhythm mRNA processing negative regulation of DNA-templated transcription negative regulation of mRNA splicing, via spliceosome positive regulation of translation regulation of alternative mRNA splicing, via spliceosome regulation of RNA splicing response to peptide ... |
arachidonic acid metabolic process cellular response to lipid establishment of skin barrier fatty acid oxidation hepoxilin biosynthetic process leukotriene A4 metabolic process linoleic acid metabolic process lipid metabolic process lipid oxidation lipoxin A4 biosynthetic process lipoxin B4 biosynthetic process lipoxyg... | cytoplasm; cytosol; membrane; sarcolemma | arachidonate 12(S)-lipoxygenase activity arachidonate 15-lipoxygenase activity hydrolase activity iron ion binding linoleate 13S-lipoxygenase activity | Rattus norvegicus | Cytoplasm Dioxygenase Fatty acid metabolism Hydrolase Iron Lipid metabolism Membrane Metal-binding Oxidoreductase Phosphoprotein Reference proteome | MGRYRVRVVT | MGRYRVRVVTGAWLFSGSVNLVRLWLVGAHREARLELQLRPARGKEEEFDFDVAEDLGPLQFVKLHKEHTVVDDAWFCNLITVQGPGMSAEAVFPCYRWVQGEGILRLPEGTARLAGDNALDVFQKHREKELKERQQTYRWATWKQGLPQTIAADCKDDLPPNMRFHEEKRLDFEWTLKAGVLEMGLKRVYTLLRSWNRLEDFDQIFWGQKSALAEKVHRCWQEDELFGYQFLNGANPMLLRRSTSLPSRLVLPPGTEELQAQLEKELKDGCLFEADFILLDGIPANVIRGEQQYLAAPLVMLRMDPSGKLLPMAIQIQP... | arachidonic acid metabolic process cellular response to lipid establishment of skin barrier fatty acid oxidation hepoxilin biosynthetic process leukotriene A4 metabolic process linoleic acid metabolic process lipid metabolic process lipid oxidation lipoxin A4 biosynthetic process lipoxin B4 biosynthetic process lipoxyg... |
exocytosis modification of dendritic spine modification of postsynaptic structure modulation of chemical synaptic transmission negative regulation of filopodium assembly negative regulation of Rac protein signal transduction neurotransmitter receptor transport, endosome to postsynaptic membrane regulation of actin cyto... | dendrite; dendritic spine; glutamatergic synapse; leading edge membrane; postsynaptic density; presynaptic active zone; recycling endosome | GTPase activator activity phospholipid binding small GTPase binding | Rattus norvegicus | Alternative splicing Cell projection Coiled coil Endosome Exocytosis GTPase activation Phosphoprotein Reference proteome Synapse | MKKQFNRMRQ | MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDELAQELIHFELRVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMDSSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRDQLSADMYSFVAKEIDYANYFQTLIEVQAEYHRKSLTLLQAVLPQIKAQQEAWVEKPSFGKPLEEHLMISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVDVQEYSADP... | exocytosis modification of dendritic spine modification of postsynaptic structure modulation of chemical synaptic transmission negative regulation of filopodium assembly negative regulation of Rac protein signal transduction neurotransmitter receptor transport, endosome to postsynaptic membrane regulation of actin cyto... |
calcium-mediated signaling negative regulation of G protein-coupled receptor internalization positive regulation of adenosine receptor signaling pathway positive regulation of ERK1 and ERK2 cascade positive regulation of glutamate receptor signaling pathway positive regulation of protein localization to membrane regula... | axon; cytoplasm; dendrite; plasma membrane | A2A adenosine receptor binding calcium ion binding type 5 metabotropic glutamate receptor binding | Rattus norvegicus | Calcium Cell membrane Cell projection Coiled coil Cytoplasm Membrane Metal-binding Methylation Reference proteome Repeat | MCERAARLCR | MCERAARLCRAGAHRLLREPPPQGRALGGLLRWVGARMGEPRAPLVPDIPAADPDPGPAAPRGGTAVILDIFRRADKNDDGKLSLEEFQLFFADGVLNEKELEGLFHTIDSDNTNHVDTKELCDYFVEHMGDYEDVLASLETLNHSVLKAMGYTKKVYEGGNNVDQFVTRFLLKETANQIQSLLSSVESAVEAIEEQTSQIRQDHCKPSPGVNESRYGGPTPPYIPNHKLVVPEPVKSLPVAIGEPKEEGLEVQISRLAELIGRLESKTLSFDLQQRLSDEEGTNMYLQLVRQEMAVCPEQLGEFLDSLRQYLRSTAEER... | calcium-mediated signaling negative regulation of G protein-coupled receptor internalization positive regulation of adenosine receptor signaling pathway positive regulation of ERK1 and ERK2 cascade positive regulation of glutamate receptor signaling pathway positive regulation of protein localization to membrane regula... |
actin filament bundle assembly cell migration cholesterol homeostasis cholesterol metabolic process intestinal cholesterol absorption negative regulation of actin filament depolymerization ruffle organization | actin cytoskeleton; brush border; brush border membrane; cleavage furrow; cytoplasm; focal adhesion; plasma membrane; ruffle; stress fiber | actin filament binding actin monomer binding metal ion binding | Rattus norvegicus | Acetylation Actin-binding Cell junction Cell membrane Cholesterol metabolism Cytoplasm Cytoskeleton LIM domain Lipid metabolism Membrane Metal-binding Phosphoprotein Reference proteome Steroid metabolism Sterol metabolism Zinc | MESTPFNRRQ | MESTPFNRRQWTSLSLRVTAKELSLVNKNKSSTIVEIFSKYQKAAEEANMERKKNNTESLPQHFRRGTLSVLKKKWENPVAGAESHTDSLPNSSSDGGHTADHPPAEVTAKAAPGARADREEHTQPRSRFGSRPEAVTQCRYPRSEDSHDFKAQATESQNMENCLGDSRHEAEKPEMSENTETSGKIEKYNVPLNRLKMMFEKGEHSQNKSPWTQGRNAGGRRLSENSCSLDDLEIGAGHLSSSAFNSEKNESKRNLELPRLSETSIKDRMAKYQAAVSKQSSPASYASELKPSESKTHKWEQKENVPPGPEACSIHQEG... | actin filament bundle assembly cell migration cholesterol homeostasis cholesterol metabolic process intestinal cholesterol absorption negative regulation of actin filament depolymerization ruffle organization actin cytoskeleton; brush border; brush border membrane; cleavage furrow; cytoplasm; focal adhesion; plasma mem... |
actin filament organization apoptotic process cell cycle cell division cell migration cell-cell adhesion gene expression immunological synapse formation inflammatory response kidney development male gonad development negative regulation of small GTPase mediated signal transduction negative regulation of transforming gr... | actin filament; axon; cell leading edge; cell periphery; cell-cell junction; cytoplasm; dendrite; endocytic vesicle; filamentous actin; late endosome; neuromuscular junction; perinuclear region of cytoplasm; plasma membrane; podosome; protein-containing complex; ruffle; vesicle | actin binding actin filament binding beta-catenin binding cadherin binding identical protein binding protein-containing complex binding SH3 domain binding vascular endothelial growth factor receptor binding | Rattus norvegicus | Cell cycle Cell division Cell junction Cell projection Coiled coil Cytoplasm Cytoskeleton Isopeptide bond Mitosis Phosphoprotein Reference proteome Repeat SH3 domain SH3-binding Ubl conjugation | MVDYIVEYDY | MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIKRETEPKDDNLPIKRERPGNVASLVQRISTYGLPAGGIQPHPQTKAMKKKTKKRQCKVLFEYSPQNEDELELTVGDVIDVIEEVEEGWWSGTLNNKLGLFPSNFVKELESTDDGEMHDAQEESEVSLTGPTSPMPSPGNGSEPAPGSVTQPKKIRGVGFGDIFKEGSVKLRTRTSSSETEEKKSEKPLILQSLGSRTQNVEVTKPDIDGKIKAKEYCKTVFPYTGTNEDELTFREGEIIHLISKETGEAGWWKGELNGKEGVF... | actin filament organization apoptotic process cell cycle cell division cell migration cell-cell adhesion gene expression immunological synapse formation inflammatory response kidney development male gonad development negative regulation of small GTPase mediated signal transduction negative regulation of transforming gr... |
aspartate transmembrane transport glutamate biosynthetic process L-glutamate transmembrane transport malate-aspartate shuttle negative regulation of glucose catabolic process to lactate via pyruvate positive regulation of ATP biosynthetic process positive regulation of glucose metabolic process positive regulation of m... | mitochondrial inner membrane; mitochondrion | 3-sulfino-L-alanine: proton, glutamate antiporter activity acidic amino acid transmembrane transporter activity aspartate:glutamate, proton antiporter activity calcium ion binding identical protein binding L-aspartate transmembrane transporter activity L-glutamate transmembrane transporter activity | Rattus norvegicus | Acetylation Calcium Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Reference proteome Repeat Transmembrane Transmembrane helix Transport | MAVKVHTTKR | MAVKVHTTKRGDPHELRNIFLQYASTEVDGEHYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYVEFTQFLQELQLEHARQAFALKDKSKSGMISGLDFSDVMVTIRSHMLTPFVEENLVSAAGGSTSHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDIEVTKEEFASAITYGVVTPINVGILYFINNVHISTGRLTLADIERIAPLAEGALPYNLAELQRQQSPGLGRPIWL... | aspartate transmembrane transport glutamate biosynthetic process L-glutamate transmembrane transport malate-aspartate shuttle negative regulation of glucose catabolic process to lactate via pyruvate positive regulation of ATP biosynthetic process positive regulation of glucose metabolic process positive regulation of m... |
aspartate transmembrane transport ATP biosynthetic process cellular respiration gluconeogenesis L-glutamate transmembrane transport malate-aspartate shuttle response to calcium ion | mitochondrial inner membrane; mitochondrion | 3-sulfino-L-alanine: proton, glutamate antiporter activity acidic amino acid transmembrane transporter activity aspartate:glutamate, proton antiporter activity calcium ion binding identical protein binding L-glutamate transmembrane transporter activity | Rattus norvegicus | Acetylation Calcium Membrane Metal-binding Methylation Mitochondrion Mitochondrion inner membrane Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix Transport | MAAAKVALTK | MAAAKVALTKRADPAELKAIFLKYASIEKNGEFFMSPHDFVTRYLNIFGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFESVLCAPDALFMVAFQLFDKAGKGEVTFEDVRQVFGQTTIHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNAKTGKVTAIDFRDIMVTIRPHVLTPFVEECLVAAAGGTRSHQVSFSYFNGFNSLLNNMELIRKIYSTLAGSRKDVEVTKEEFALAAQKFGQVTPMEVDILFQLADLYEPRGRMTLADIERIAPLEEGMLPFNLAEAQRQQKASGDAAR... | aspartate transmembrane transport ATP biosynthetic process cellular respiration gluconeogenesis L-glutamate transmembrane transport malate-aspartate shuttle response to calcium ion mitochondrial inner membrane; mitochondrion 3-sulfino-L-alanine: proton, glutamate antiporter activity acidic amino acid transmembrane tran... |
activation of innate immune response antiviral innate immune response autophagosome assembly cellular response to exogenous dsRNA cellular response to interferon-beta cellular response to organic cyclic compound cGAS/STING signaling pathway cytoplasmic pattern recognition receptor signaling pathway defense response to ... | autophagosome; autophagosome membrane; cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; endosome; Golgi apparatus; Golgi membrane; mitochondrial outer membrane; perinuclear region of cytoplasm; peroxisome; plasma membrane; STING complex | 2',3'-cyclic GMP-AMP binding cyclic-di-GMP binding identical protein binding protein homodimerization activity protein kinase binding proton channel activity RNA polymerase II-specific DNA-binding transcription factor binding signaling adaptor activity ubiquitin protein ligase binding | Rattus norvegicus | 3D-structure Autophagy Cell membrane Cytoplasm Cytoplasmic vesicle Endoplasmic reticulum Golgi apparatus Immunity Innate immunity Isopeptide bond Lipoprotein Membrane Mitochondrion Mitochondrion outer membrane Nucleotide-binding Palmitate Phosphoprotein Reference proteome Transmembrane Transmembrane helix Ubl conjugati... | MPYSNLHPSI | MPYSNLHPSIPRPRSYRFKLAAFVLLVGSLMSLWMTGEPPSHTLHYLALHVASQQLGLLLKKLCCLAEELCHVQSRYQGSYWKAVRACVGSPICFMALILLSFYFYCSLENTSDLRLAWHLGILVLSKSLSMTLDLQSLAPAEVSAVCEEKNFNVAHGLAWSYYIGYLKLILPGLQARIRMFNQLHNNMLSGAGSRRLYILFPLDCGVPDDLSVADPNIRFRDMLPQQNTDRAGVKNRAYSNSVYELLENGQPAGACILEYATPLQTLFAMSQDGKAGFSREDRLEQAKLFCRTLEEILADVPESRNHCRLIVYQESEEG... | activation of innate immune response antiviral innate immune response autophagosome assembly cellular response to exogenous dsRNA cellular response to interferon-beta cellular response to organic cyclic compound cGAS/STING signaling pathway cytoplasmic pattern recognition receptor signaling pathway defense response to ... |
actin crosslink formation actin cytoskeleton organization actin filament bundle assembly actin polymerization-dependent cell motility adult locomotory behavior barbed-end actin filament capping behavioral response to ethanol cellular response to leukemia inhibitory factor dendritic cell migration exit from mitosis posi... | brush border; cell cortex; glutamatergic synapse; growth cone; NMDA selective glutamate receptor complex; plasma membrane; postsynaptic density; ruffle membrane; stereocilium; stereocilium bundle; stereocilium tip; synapse | actin binding small GTPase binding | Rattus norvegicus | Actin-binding Cell membrane Cell projection Cytoplasm Membrane Phosphoprotein Reference proteome SH3 domain Synapse Synaptosome Ubl conjugation | MNGHMSNHSS | MNGHMSNHSSGYGIYPSQMNGYGSSPPYSQMDREHCSRTSAKALYEQRKNYARDSVSSVSDVSQYRVEHLTTFVLDRKDAMITVDDGIRKLKLLDAKGKVWTQDMILQVDDRAVSLIDLESKNELENFPLNTIQHCQAVAHTCSYDSILALVCKEPTQNKPDLHLFQCDEVKANLISEDIESAISDSKGGKQKRRPEALRMIAKADPGIPPPPRAPAPVPPGTVTQVDVRSRVAAWSAWAADQGDFEKPRQYHEQEETPEMMAARIDRDVQILNHILDDIEFFITKLQKAAEAFSELSKRKKSKKSKRKGPGEGVLTLRA... | actin crosslink formation actin cytoskeleton organization actin filament bundle assembly actin polymerization-dependent cell motility adult locomotory behavior barbed-end actin filament capping behavioral response to ethanol cellular response to leukemia inhibitory factor dendritic cell migration exit from mitosis posi... |
adult feeding behavior behavioral fear response behavioral response to ethanol proteolysis regulation of postsynaptic neurotransmitter receptor internalization regulation of synaptic transmission, GABAergic righting reflex | cytoplasm; cytosol; glutamatergic synapse; nucleus; synapse | cysteine-type deubiquitinase activity deubiquitinase activity metal ion binding | Rattus norvegicus | Behavior Cytoplasm Hydrolase Metal-binding Protease Reference proteome Thiol protease Ubl conjugation pathway Zinc | MTVRNIASIC | MTVRNIASICNMGTNASALEKDIGPEQFPINEHYFGLVNFGNTCYCNSVLQALYFCRPFRENVLAYKAQQKKKENLLTCLADLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNMNEPAENSKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKS... | adult feeding behavior behavioral fear response behavioral response to ethanol proteolysis regulation of postsynaptic neurotransmitter receptor internalization regulation of synaptic transmission, GABAergic righting reflex cytoplasm; cytosol; glutamatergic synapse; nucleus; synapse cysteine-type deubiquitinase activity... |
activation of innate immune response apoptotic process defense response to bacterium detection of bacterium inflammatory response innate immune response positive regulation of apoptotic process positive regulation of interleukin-1 beta production positive regulation of protein processing protein homooligomerization pyr... | cytosol; intracellular membrane-bounded organelle; IPAF inflammasome complex; plasma membrane | ATP binding caspase binding endopeptidase activator activity identical protein binding protein homodimerization activity | Rattus norvegicus | Apoptosis ATP-binding Cytoplasm Immunity Inflammatory response Innate immunity Leucine-rich repeat Nucleotide-binding Phosphoprotein Reference proteome Repeat | MNFIKENSQA | MNFIKENSQALIQRMGIVVIKQICDDLFALNVLNGEEVAIICSHRVEQDAARDIVHMILKKGSAACNLFLKSLENWNYPVYQDLTGHSLFHQNLEEDLDVLAQSLKDLYNSPVFKNFFPLGEDIDIIFNLQITFTEPVLWRKDHRHHRVEQMTLGSLLEALKSPCLIEGESGKGKSTLLQKIAMLWASGMCPALNQFKLVFFIRLSSARGGLFETLYDQLVNIPDSISKPTFRALLLKLHKKVLFLLDAYNEFHPQNCPEIEALVKENHRFKNMVIVTTTTECLRHIRHVGALTVEVGDMTEDSARVLIREVLINELAEG... | activation of innate immune response apoptotic process defense response to bacterium detection of bacterium inflammatory response innate immune response positive regulation of apoptotic process positive regulation of interleukin-1 beta production positive regulation of protein processing protein homooligomerization pyr... |
adherens junction maintenance bundle of His cell-Purkinje myocyte adhesion involved in cell communication cardiac muscle cell action potential cardiac muscle cell action potential involved in contraction cell-cell adhesion cell-cell junction assembly cell-cell signaling involved in cardiac conduction desmosome assembly... | adherens junction; cell junction; cell-cell junction; cytoplasm; desmosome; intercalated disc; intermediate filament; nucleus; plasma membrane | alpha-catenin binding cadherin binding intermediate filament binding molecular adaptor activity protein kinase C binding | Rattus norvegicus | Alternative splicing Cell adhesion Cell junction Cytoplasm Methylation Nucleus Phosphoprotein Reference proteome Repeat | MAIPGSLGEC | MAIPGSLGECGYIRTVLGQQILGHLDSSSLALPSEARLRLAGSSGRGDPVARSQRIQEQVQQTLARRGRSSVVGGNLHRTSSVPEYVYKLHLVENDFVGRQSPAARDYDMLKVGLSGWRDGSTLKVPCTSIKPHREKKTWIEALREGLEHTTDHTDCPAHYVYSHYYFNSKKSNILVFQHIKDKSLQRNAIILLSPEHCTCQHVRLIPSSVLPSLFNQLQLSPELYFSNMGTLYMTSIKGTLCIQLLKGKLPAKHQANFVTMAERRVYTLLLSSTTSSETSFRRTGDTLPSVTSGQSRVHGLHFHHVICDCLSRNADLEM... | adherens junction maintenance bundle of His cell-Purkinje myocyte adhesion involved in cell communication cardiac muscle cell action potential cardiac muscle cell action potential involved in contraction cell-cell adhesion cell-cell junction assembly cell-cell signaling involved in cardiac conduction desmosome assembly... |
actin filament organization cell migration cell-cell junction organization cellular response to insulin stimulus establishment of apical/basal cell polarity establishment or maintenance of epithelial cell apical/basal polarity eye photoreceptor cell development Golgi vesicle budding intracellular signal transduction ne... | apical part of cell; apical plasma membrane; brush border; cell leading edge; cytoplasm; cytosol; endosome; glutamatergic synapse; Golgi membrane; intercellular bridge; microtubule cytoskeleton; nucleus; PAR polarity complex; Schaffer collateral - CA1 synapse; Schmidt-Lanterman incisure | ATP binding diacylglycerol-dependent serine/threonine kinase activity metal ion binding phospholipid binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Rattus norvegicus | Acetylation ATP-binding Cytoplasm Developmental protein Endosome Kinase Membrane Metal-binding Nucleotide-binding Nucleus Phosphoprotein Proto-oncogene Reference proteome Serine/threonine-protein kinase Transferase Tumor suppressor Zinc Zinc-finger | MPTQRDSSTM | MPTQRDSSTMSHTVACGGGGDHSHQVRVKAYYRGDIMITHFEPSISFEGLCSEVRDMCSFDNEQPFTMKWIDEEGDPCTVSSQLELEEAFRLYELNKDSELLIHVFPCVPERPGMPCPGEDKSIYRRGARRWRKLYCANGHTFQAKRFNRRAHCAICTDRIWGLGRQGYKCINCKLLVHKKCHKLVTIECGRHSLPPEPMMPMDQSSMHPDHTQTVIPYNPSSHESLDQVGEEKEAMNTRESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHS... | actin filament organization cell migration cell-cell junction organization cellular response to insulin stimulus establishment of apical/basal cell polarity establishment or maintenance of epithelial cell apical/basal polarity eye photoreceptor cell development Golgi vesicle budding intracellular signal transduction ne... |
asymmetric neuroblast division cartilage condensation cartilage development cell fate commitment cellular response to transforming growth factor beta stimulus central nervous system neuron differentiation chondrocyte differentiation in utero embryonic development negative regulation of DNA-templated transcription oligo... | nucleus; transcription regulator complex | cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding transcription cis-regulatory region binding | Rattus norvegicus | Activator Alternative splicing Coiled coil Differentiation DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MLTDPDLPQE | MLTDPDLPQEFERMSSKRPASPYGETDGEVAMVTSRQKVEEEESERLPAFHLPLHVSFPNKPHSEEFQPVSLLTQEACGPRTPAAQHSTMEVDGNKVMSSLAPYNSSTSPQKAEEGGRQSGESVSSAALGTPERRKGSLADVVDTLKQRKMEELIKNEPEDTPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIP... | asymmetric neuroblast division cartilage condensation cartilage development cell fate commitment cellular response to transforming growth factor beta stimulus central nervous system neuron differentiation chondrocyte differentiation in utero embryonic development negative regulation of DNA-templated transcription oligo... |
endocytosis positive regulation of Notch signaling pathway protein phosphorylation protein stabilization regulation of clathrin-dependent endocytosis regulation of protein localization | cell leading edge; clathrin-coated pit; clathrin-coated vesicle; terminal bouton | AP-2 adaptor complex binding ATP binding Notch binding protein serine kinase activity protein serine/threonine kinase activity | Bos taurus | Acetylation ATP-binding Cell membrane Cell projection Coated pit Endocytosis Kinase Membrane Methylation Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Synapse Transferase | MKKFFDSRRE | MKKFFDSRREQGGSGLGSGSSGGGGSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIVFLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINSVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKVITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECP... | endocytosis positive regulation of Notch signaling pathway protein phosphorylation protein stabilization regulation of clathrin-dependent endocytosis regulation of protein localization cell leading edge; clathrin-coated pit; clathrin-coated vesicle; terminal bouton AP-2 adaptor complex binding ATP binding Notch binding... |
bone mineralization bone remodeling canonical Wnt signaling pathway involved in metanephric kidney development cell differentiation involved in metanephros development circadian regulation of gene expression digestive tract development epithelial cell proliferation involved in renal tubule morphogenesis G protein-coupl... | extracellular matrix; extracellular space; plasma membrane | protein-hormone receptor activity transmembrane signaling receptor activity | Bos taurus | Biological rhythms Cell membrane Developmental protein Differentiation Disulfide bond G-protein coupled receptor Glycoprotein Immunity Innate immunity Leucine-rich repeat Membrane Phosphoprotein Receptor Reference proteome Repeat Signal Spermatogenesis Transducer Transmembrane Transmembrane helix Wnt signaling pathway | MPGPLGLLCF | MPGPLGLLCFLALGLRGSAEPSGAAPPLCAAPCSCDGDRRVDCSGKGLTAVPEGLSAFTQLLDISMNNITQLPEDAFKNFPFLEELRLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSSLQSLRLDANHITSVPEDSFEGLTQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIKSLGQHCFDGLDNLETLDLNYNNLGEFPQAIKALPSLKELLFHSNSISVIPDGAFDGNPLLKTIHLYDNPLSFVGNSAFHNLSELHSLVIRGASMVQRFPNLTGTVR... | bone mineralization bone remodeling canonical Wnt signaling pathway involved in metanephric kidney development cell differentiation involved in metanephros development circadian regulation of gene expression digestive tract development epithelial cell proliferation involved in renal tubule morphogenesis G protein-coupl... |
positive regulation of toll-like receptor 4 signaling pathway proteasome-mediated ubiquitin-dependent protein catabolic process protein K48-linked ubiquitination | cytoplasm; cytosol; endosome; intracellular membrane-bounded organelle; lysosome; membrane; synaptic vesicle membrane | metal ion binding ubiquitin protein ligase activity ubiquitin-protein transferase activity | Bos taurus | Cytoplasmic vesicle Endosome Lipoprotein Lysosome Membrane Metal-binding Myristate Phosphoprotein Reference proteome Synapse Transferase Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger | MGGKQSTAAR | MGGKQSTAARSRGPFPGVSTDDSAVPPPGGAPHFGHYRAGGGAMGLRSRSVSSVAGMGMDPSSAGGVSFGLYTPASRGAGDAERAPGSGGSASDSTYAHGNGYQETGGGHHRDGMLYLGSRASLADALPLHIAPRWFSSHSGFKCPICSKSVASDEMEMHFIMCLSKPRLSYNDDVLTKDAGECVICLEELLQGDTIARLPCLCIYHKSCIDSWFEVNRSCPEHPAD | positive regulation of toll-like receptor 4 signaling pathway proteasome-mediated ubiquitin-dependent protein catabolic process protein K48-linked ubiquitination cytoplasm; cytosol; endosome; intracellular membrane-bounded organelle; lysosome; membrane; synaptic vesicle membrane metal ion binding ubiquitin protein liga... |
DNA damage response DNA repair lung development negative regulation of gene expression negative regulation of osteoclast development Notch signaling pathway positive regulation of ERK1 and ERK2 cascade positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway positive regulation of pr... | chromosome; cytoplasm; endoplasmic reticulum; Golgi apparatus; mitochondrion; nucleolus; nucleoplasm; nucleus; Parkin-FBXW7-Cul1 ubiquitin ligase complex; perinuclear region of cytoplasm; SCF ubiquitin ligase complex | cyclin binding identical protein binding phosphothreonine residue binding ubiquitin binding ubiquitin ligase-substrate adaptor activity ubiquitin protein ligase binding ubiquitin-protein transferase activator activity | Bos taurus | Alternative splicing Chromosome DNA damage DNA repair Nucleus Phosphoprotein Reference proteome Repeat Ubl conjugation Ubl conjugation pathway WD repeat | MNQELLSVGS | MNQELLSVGSKRRRTGGSLRGNPSSSQADEEQMNRVLEEEQQQPRHQEEEHAARNGEVVGAEPRPGDQNDPQQGQLEENNNRFISVDEDSSGNQEEQEEDEEHAGEQDEEDEEEEEMDQESDDFDQSDDSSREDEHTHRNSVTNSNSIVDLPIHQRSSPFYTKTTKMKRKLDHGSEVRSFSLGKKPCKVSEYTSTTGLVPCSATPTTFGDLRAANGQGQQRRRITSVQPPTGLQEWLKMFQSWSGPEKLLALDELIDSCEPTQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLW... | DNA damage response DNA repair lung development negative regulation of gene expression negative regulation of osteoclast development Notch signaling pathway positive regulation of ERK1 and ERK2 cascade positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway positive regulation of pr... |
defense response to bacterium defense response to virus interleukin-27-mediated signaling pathway negative regulation of viral genome replication positive regulation of interferon-beta production positive regulation of tumor necrosis factor production regulation of lactation response to virus type I interferon-mediated... | cytosol; membrane; nucleoplasm; perinuclear region of cytoplasm | 2'-5'-oligoadenylate synthetase activity ATP binding double-stranded RNA binding metal ion binding | Bos taurus | Antiviral defense ATP-binding Cytoplasm Glycoprotein Immunity Innate immunity Lipoprotein Magnesium Metal-binding Myristate Nucleotide-binding Nucleotidyltransferase Reference proteome Repeat RNA-binding Transferase | MGSRESHLYE | MGSRESHLYEKPSEKLEEFIQNHLRPSEDCQKDIDQSVDTICEVLQEPCPSLTVTGVAKGGSYGRRTVLRGNSDGILVVFFGDLEQFQDQEKRQYELLSKIWAQMKHCESTWKLAAKMELQNTNRSSRVTIQLSTKQQSITFNVLPAFNALGLSEKSSLWSYRELKRSLDMVKARPGEFSVCFTELQEKFFSNYPSKLKDLILLVKHWFQKCQEKLINSSLLPPYALELLTVYAWEQGCGAEDFDMAEGVRTVLRLIEKQEQLCVYWTVNYNFGDEIVRNILLSQLQAPRPVILDPTDPTNNVSMDNTCWLQLKHEAQNW... | defense response to bacterium defense response to virus interleukin-27-mediated signaling pathway negative regulation of viral genome replication positive regulation of interferon-beta production positive regulation of tumor necrosis factor production regulation of lactation response to virus type I interferon-mediated... |
brain development cardioblast differentiation heart development peptide hormone processing protein processing | cytoplasmic vesicle membrane; Golgi membrane; plasma membrane; transport vesicle membrane | metal ion binding metalloendopeptidase activity | Bos taurus | Alternative splicing Cytoplasmic vesicle Disulfide bond Glycoprotein Golgi apparatus Hydrolase Membrane Metal-binding Metalloprotease Protease Reference proteome Signal-anchor Transmembrane Transmembrane helix Zinc | MSVALQELGG | MSVALQELGGGGNMVEYKRATLRDEDAPETPVEGGASPDAVEAGFRKRTSRLLGLHTQLELVLAGVSLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAERKTQRFYLSCLQVERIEELGAQPLRDLIDKIGGWNVTGPWDQDNFMEVLKAVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGQPTSTREQMRQVLELEIQLANITVPQDQRR... | brain development cardioblast differentiation heart development peptide hormone processing protein processing cytoplasmic vesicle membrane; Golgi membrane; plasma membrane; transport vesicle membrane metal ion binding metalloendopeptidase activity Bos taurus Alternative splicing Cytoplasmic vesicle Disulfide bond Glyco... |
choline metabolic process lipid catabolic process lipid metabolic process | plasma membrane; side of membrane | glycerophosphocholine cholinephosphodiesterase activity glycerophosphodiester phosphodiesterase activity metal ion binding | Bos taurus | Cell membrane Direct protein sequencing Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipid degradation Lipid metabolism Lipoprotein Membrane Metal-binding Phosphoprotein Reference proteome Signal Zinc | MAGKLGVLLL | MAGKLGVLLLALVLSLAQPASARRKLLVFLLDGFRADYISDEALESLPGFKEIVSRGVKVDYLTPDFPTLSYPNYYSLMTGRHCEVHQMTGNYMWDPDTNKSFDLGINRDSRLPLWWNGSEPLWVTLTKAKRKVYMYYWPGCEVEILGVRPTYCLEYKSVPTDINFVNAVSGALDVFKSGQADLAAIYYERVDVEGHHYGPSSPQRKDAVKAVDTVMAYMTKWIQERDLQDDLNVIIFSDHGMTDISWTDKVIKLDNYINLRDLQQLKGRGPVVSLWPAPGKHSEIYNKVRRVEHMTVYAKEDIPSRFYYKKGKFVSPLT... | choline metabolic process lipid catabolic process lipid metabolic process plasma membrane; side of membrane glycerophosphocholine cholinephosphodiesterase activity glycerophosphodiester phosphodiesterase activity metal ion binding Bos taurus Cell membrane Direct protein sequencing Disulfide bond Glycoprotein GPI-anchor... |
cell division G1/S transition of mitotic cell cycle protein deubiquitination protein K11-linked deubiquitination protein K48-linked deubiquitination proteolysis regulation of DNA replication | chromosome; cytosol; nucleus | cysteine-type deubiquitinase activity cysteine-type endopeptidase activity protein kinase binding | Bos taurus | Cell cycle Cell division Chromosome Hydrolase Mitosis Nucleus Phosphoprotein Protease Reference proteome Repeat Thiol protease Ubl conjugation Ubl conjugation pathway | MSPLKIHGPI | MSPLKIHGPIRIRSMQTGITKWKEGSFEVVEKENKVSLVVHYNTGGIPRIFQLSHNIKNVVLRPSGAKQSRLMLTLQDNSFLSIDKVPSKDAEEMRLFLDAVHQNRLNAAMKPSQGSGSFGAILGSRTSQKETNRQLSYSDNQVSSKRGSLETKDDTPFRKVLGNPSRGSIKAAAGNGVTPARTIPSLTSTSTPLRSGLLENRTEKRKRMLSSGSELNEDYPKENDSSSNNKAMTDPSRKYLTSSREKQLSLKQSEENRTSGLLPLQSSSFYGSRTAAKDYSPGSTNLDRTNISSQTPSAKRSLGFLPQPAPLSVKKLRC... | cell division G1/S transition of mitotic cell cycle protein deubiquitination protein K11-linked deubiquitination protein K48-linked deubiquitination proteolysis regulation of DNA replication chromosome; cytosol; nucleus cysteine-type deubiquitinase activity cysteine-type endopeptidase activity protein kinase binding Bo... |
carbohydrate transport organic substance transport | endoplasmic reticulum membrane; plasma membrane | lysophospholipid:sodium symporter activity | Gallus gallus | 3D-structure Cell membrane Disulfide bond Endoplasmic reticulum Glycoprotein Lipid transport Membrane Reference proteome Symport Transmembrane Transmembrane helix Transport | MAGGGGAERV | MAGGGGAERVRVGAAAAGLLPPSCRQPRRRESRERLSVCSKLCYAVGGAPYQTTGCALGFFLQIYLLDVAQLDPFYASIILFVGRAWDAITDPMVGFFISKTPWTRFGRLMPWIIFSTPFAVISYFLIWFVPDISTGQVMWYLIFYCIFQTLVTCFHVPYSALTMFISREQSERDSATAYRMTVEVLGTVLGTAIQGQIVGKAVTPCIENPPFLSETNFSVAIRNVNMTHYTGSLADTRNAYMVAAGVIGGLYILCAVILSVGVREKRESSELQSDEPVSFFRGLKLVMNHGAYIKLITGFLFTSLAFMLLEGNFALFCT... | carbohydrate transport organic substance transport endoplasmic reticulum membrane; plasma membrane lysophospholipid:sodium symporter activity Gallus gallus 3D-structure Cell membrane Disulfide bond Endoplasmic reticulum Glycoprotein Lipid transport Membrane Reference proteome Symport Transmembrane Transmembrane helix T... |
DNA damage response double-strand break repair via homologous recombination negative regulation of double-strand break repair via homologous recombination protein ubiquitination replication fork processing | chromatin; nucleus; SCF ubiquitin ligase complex | 3'-5' DNA helicase activity ATP binding ATP hydrolysis activity DNA helicase activity double-stranded DNA binding isomerase activity single-stranded DNA binding | Gallus gallus | ATP-binding Chromosome DNA damage DNA repair DNA-binding Helicase Hydrolase Isomerase Nucleotide-binding Nucleus Reference proteome Ubl conjugation pathway | MHLTADDCEA | MHLTADDCEALSRSTEGLSSLTQPLNQRRSRGDVNRGLQPTHRTRTQPGAQGRQKNIMDYFKVSQRQQAVAGRTKDISIKEEVLDPFFAEDDESSISSVMETSGDSSSFLENEYMGNSRKRPLSSTAPGRLQIENDLWGEPEKKAVVVHPEHSQIKQELDDEIEIEPVPDSHYGLLGTRNWEVPQGSIEDLPDEVLRSIFAFLPVTDLYQSLSLVCRRWRIIVGDPWFIPWKKLYHQYLVKEDMALRRVEQVLQDFAITGQHKECILGLIRCVSTIPTSRNVDPSAVLQCLKGHHLFSRAEVCITNKLPHLQSKTGPEYM... | DNA damage response double-strand break repair via homologous recombination negative regulation of double-strand break repair via homologous recombination protein ubiquitination replication fork processing chromatin; nucleus; SCF ubiquitin ligase complex 3'-5' DNA helicase activity ATP binding ATP hydrolysis activity D... |
potassium ion import across plasma membrane potassium ion transport protein homotetramerization regulation of monoatomic ion transmembrane transport | membrane; monoatomic ion channel complex; plasma membrane | identical protein binding inward rectifier potassium channel activity | Gallus gallus | 3D-structure Cell membrane Disulfide bond Ion channel Ion transport Membrane Potassium Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel | MTAGRVNPYS | MTAGRVNPYSIVSSEEDGLRLTTMPGINGFGNGKIHTRRKCRNRFVKKNGQCNVEFTNMDDKPQRYIADMFTTCVDIRWRYMLLLFSLAFLVSWLLFGLIFWLIALIHGDLENPGGDDTFKPCVLQVNGFVAAFLFSIETQTTIGYGFRCVTEECPLAVFMVVVQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVAMRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRITEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEINEDSPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLASE... | potassium ion import across plasma membrane potassium ion transport protein homotetramerization regulation of monoatomic ion transmembrane transport membrane; monoatomic ion channel complex; plasma membrane identical protein binding inward rectifier potassium channel activity Gallus gallus 3D-structure Cell membrane Di... |
folate import across plasma membrane transmembrane transport | apical plasma membrane; basolateral plasma membrane; endosome; endosome membrane; plasma membrane | folic acid binding folic acid:proton symporter activity methotrexate transmembrane transporter activity transmembrane transporter activity | Gallus gallus | 3D-structure Cell membrane Cytoplasm Disulfide bond Endosome Folate-binding Glycoprotein Membrane Reference proteome Symport Transmembrane Transmembrane helix Transport | MAAPSDPPTA | MAAPSDPPTAATPPAPPPPARRCLLAPSVEPLLFLATLALGLQVPLATQYLWDRLGAERGYVGPNASSPHGCGNGSGAVDPLREEVEALVAHWNLCINLGGFFVGLFSVTLFGPWSDSVGRRPVLVLPAVGMAVQAAVYLLVMYLRLHVAYLLLGRIISGLLGDYNLILAGCFASVADSSNQRTRTFRVAILEACLGVAGMVASVGGGQWRKAEGYINPFWLVLAASLAAALYAALCLQETVKQRRAAKLLTLQHYKAVYKLYTAPEDLSSRRKLALYSLAFFLLVTVHFGTKDLYVLYELGSPLCWASDLIGYGSAASY... | folate import across plasma membrane transmembrane transport apical plasma membrane; basolateral plasma membrane; endosome; endosome membrane; plasma membrane folic acid binding folic acid:proton symporter activity methotrexate transmembrane transporter activity transmembrane transporter activity Gallus gallus 3D-struc... |
intracellular monoatomic cation homeostasis | endoplasmic reticulum lumen; extracellular space; plasma membrane | 3-phytase activity 4-phytase activity acid phosphatase activity bisphosphoglycerate 3-phosphatase activity inositol bisphosphate phosphatase activity inositol hexakisphosphate 2-phosphatase activity inositol pentakisphosphate phosphatase activity inositol phosphate phosphatase activity inositol trisphosphate phosphatas... | Gallus gallus | Cell membrane Endoplasmic reticulum Glycoprotein Hydrolase Membrane Reference proteome Secreted Signal | MAPRRAACLL | MAPRRAACLLPLLVAVASAGLGGYFGTKSRYEEVNPHLAEDPLSLGPHAAASRLPAACAPLQLRAVLRHGTRYPTAGQIRRLAELHGRLRRAAAPSCPAAAALAAWPMWYEESLDRLAPRGRRDMEHLARRLAARFPALFAARRRLALASSSKHRCLQSGAAFRRGLGPSLSLGADETEIEVNDALMRFFDHCDKFVAFVEDNDTAMYQVNAFKEGPEMRKVLEKVASALCLPASELNADLVQVAFLTCSYELAIKNVTSPWCSLFSEEDAKVLEYLNDLKQYWKRGYGYDINSRSSCILFQDIFQQLDKAVDESRSSKP... | intracellular monoatomic cation homeostasis endoplasmic reticulum lumen; extracellular space; plasma membrane 3-phytase activity 4-phytase activity acid phosphatase activity bisphosphoglycerate 3-phosphatase activity inositol bisphosphate phosphatase activity inositol hexakisphosphate 2-phosphatase activity inositol pe... |
mismatch repair mitotic G2 DNA damage checkpoint signaling positive regulation of B cell proliferation positive regulation of isotype switching to IgA isotypes positive regulation of isotype switching to IgG isotypes somatic hypermutation of immunoglobulin genes somatic recombination of immunoglobulin gene segments | cytosol; MutLalpha complex; nucleoplasm | ATP binding ATP hydrolysis activity ATP-dependent DNA damage sensor activity endonuclease activity MutSalpha complex binding single base insertion or deletion binding single-stranded DNA binding | Gallus gallus | ATP-binding DNA damage Endonuclease Hydrolase Nuclease Nucleotide-binding Nucleus Reference proteome | MEEAAPCSEP | MEEAAPCSEPAKTIKRIDRESVHRICSGQVVLSLGTAVKELVENSLDAGATNIDVRLKDHGAELIEVSDNGGGVEEENFEGLTLKHYTSKIQDFSDLIHVETFGFRGEALSSLCALSDVTISTCHKSAKVGTRLVFDHNGKITQKAPYPRQQGTTVSIQQLFHTLPVRHKEFQRNIKKEYAKMVQILQAYCIISKGVRINCTNQVGQGKKSPVVSTTGGPNLKENIGAVFGKKQLQSLIPFVQLPPNEAVCEEYGLKSTDLPEKLYSITGFISRCDHGVGRSTTDRQFFFINQRPCDPAKVVKLVNEVYHLYNKHQYPFI... | mismatch repair mitotic G2 DNA damage checkpoint signaling positive regulation of B cell proliferation positive regulation of isotype switching to IgA isotypes positive regulation of isotype switching to IgG isotypes somatic hypermutation of immunoglobulin genes somatic recombination of immunoglobulin gene segments cyt... |
biomineral tissue development shell calcification | extracellular matrix; extracellular region; extracellular space; secretory granule | extracellular matrix protein binding | Gallus gallus | Direct protein sequencing Disulfide bond Extracellular matrix Glycoprotein Reference proteome Secreted Signal | MRATLFCLCL | MRATLFCLCLCLLGTVLPTPVSLPARARGNCPGQHQILLKGCNTKHGFYIFQYIYSHLMQKNQTQVKKEEGDHQGTIHGHWLGKVDGEAPGQGAGSSHVPEDKDSPKTHSHITPASKGEGRALRPGIGDSNSVYPTSTSVEGSGDMGSILLGEIINGEDGLPQSTHPGGPHGDGDGGNGVLVDGAVTAGRERASGSEGAGSEGGSHAPVPDQGQAGTMGTGDSAITSVTDSAITSVTKKEDVHVDTEGIDEFAYIPDVDAVTITRGQDGETHISPEDEVKIFIGRANIQVGENDSSVGSAGATSEANVIPTVVTVRPQGH... | biomineral tissue development shell calcification extracellular matrix; extracellular region; extracellular space; secretory granule extracellular matrix protein binding Gallus gallus Direct protein sequencing Disulfide bond Extracellular matrix Glycoprotein Reference proteome Secreted Signal MRATLFCLCL MRATLFCLCLCLLGT... |
axon guidance cell-cell adhesion via plasma-membrane adhesion molecules embryonic morphogenesis fibroblast growth factor receptor signaling pathway head development heart development neuron projection development neuron projection extension positive regulation of synapse assembly proepicardium cell migration involved i... | axon terminus; axonal growth cone; cell-cell junction; cytosol; endoplasmic reticulum membrane; extracellular space; focal adhesion; glutamatergic synapse; growth cone membrane; plasma membrane; postsynaptic membrane; synaptic membrane | chemorepellent activity fibroblast growth factor receptor binding protein homodimerization activity | Gallus gallus | Cell adhesion Cell junction Cell membrane Cell projection Developmental protein Disulfide bond Endoplasmic reticulum Glycoprotein Leucine-rich repeat Membrane Reference proteome Repeat Secreted Signal Transmembrane Transmembrane helix | MITVPWSVFL | MITVPWSVFLIWTKIGLLLDMAPYSVAAKPCPSVCRCDVGFIYCNDRDLTSIPTGIPEDATNLFLQNNQINNAGIPSELKNLRRVERIFLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSQIPYLEELHLDDNSVSAVSIEDGAFRDNIYLRLLFLSRNHLSTIPWGLPKTIEELRLDDNRISTISELSLQDLTNLKRLVLDGNLLNNHGLGDKVFMNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQENHINHVPPNAFSYLRQLYRLDMSNNNLSNLPQGVFDDLDNITQLFLRNNPWHCGCKMKWVRDWL... | axon guidance cell-cell adhesion via plasma-membrane adhesion molecules embryonic morphogenesis fibroblast growth factor receptor signaling pathway head development heart development neuron projection development neuron projection extension positive regulation of synapse assembly proepicardium cell migration involved i... |
defense response to bacterium execution phase of apoptosis lymphocyte apoptotic process positive regulation of plasma membrane repair proteolysis | cytoplasm; cytosol; extracellular space; nucleus | aspartic-type endopeptidase activity cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in execution phase of apoptosis RNA binding | Gallus gallus | Allosteric enzyme Apoptosis Cytoplasm Hydrolase Nucleus Protease Reference proteome RNA-binding Secreted Thiol protease Zymogen | MSGDQHADRS | MSGDQHADRSSGEKSNGDQDDTVDAKPDRSSRLSLFAKKKKNGEEEQPKSSLSNQYRIVTPTFQYNMNYKKVGKCIIINNKNFEDKTGMGTRNGTDKDAGDLSKSFRSLGFDVYTYNDRSCEDMQTLLKQAAEENHSDAACFACILLSHGEEGLIYGTDGPMAIKHLTTLFRGDKCKTLIGKPKLFFIQACRGSEFDEGIQTDSGPANDTLETDANPRYKIPVEADFLFAYSTVPGYYSWRNPGRGSWFVQSLCSVLNEHGKQLEIMQILTRVNYVVATNFESQSDDPRFSEKKQIPCVVSMLTKELYF | defense response to bacterium execution phase of apoptosis lymphocyte apoptotic process positive regulation of plasma membrane repair proteolysis cytoplasm; cytosol; extracellular space; nucleus aspartic-type endopeptidase activity cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopep... |
DNA protection purine nucleoside catabolic process | acrosomal vesicle; cytoplasm; nuclear membrane | 2-hydroxy-ATP hydrolase activity 2-hydroxy-dATP hydrolase activity 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity dATP diphosphatase activity metal ion binding N6-methyl-(d)ATP hydrolase activity O6-methyl-dGTP hydrolase activity RN... | Canis lupus familiaris | 3D-structure Cytoplasm Cytoplasmic vesicle Hydrolase Magnesium Membrane Metal-binding Nucleus Reference proteome RNA-binding | MGTSRLYTLV | MGTSRLYTLVLVLQPERVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGAKRELREESGLTVDTLHKVGQIMFEFVGEPELMDVHIFCTDSVQGTPVESDEMRPQWFQLDQIPFTDMWPDDSYWFPLLLQKKKFHGYFRFQGPNTILDYTLREVDKL | DNA protection purine nucleoside catabolic process acrosomal vesicle; cytoplasm; nuclear membrane 2-hydroxy-ATP hydrolase activity 2-hydroxy-dATP hydrolase activity 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity dATP diphosphatase a... |
adherens junction organization calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules cell morphogenesis cell-cell adhesion mediated by cadherin cell-cell junction assembly homophilic cell adhesion via plasma membrane adhesion molecules regulation of gene expression synapse assembly | adherens junction; apical junction complex; catenin complex; cell-cell junction; endosome; flotillin complex; Golgi apparatus; plasma membrane | cadherin binding calcium ion binding | Canis lupus familiaris | Calcium Cell adhesion Cell junction Cell membrane Cleavage on pair of basic residues Disulfide bond Endosome Glycoprotein Golgi apparatus Membrane Metal-binding Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix Ubl conjugation | MGPRYGGAPA | MGPRYGGAPALLLPLLLLLQVSSGLCQEPEPCRPGFGADSYTFTVPRRHLERGRVLGRVSFEGCTGLPRTAYVSDDTRFKVGTDGVITVKRPLQLHKPEISFLVHAWDSSRRKLSTRVRLKAATHHHHHHHDAPSKTQTEVLTFPSSQHGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNRDKEIKVFYSITGQGADAPPVGVFIIERETGWLKVTEPLDREQIAKYILYSHAVSSNGNAVEDPMEIVITVTDQNDNKPEFTQAVFQGSVTEGALPGTSVMQVTATDADDDVNTYNAAIAYSILTQDPLLPSSMMFT... | adherens junction organization calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules cell morphogenesis cell-cell adhesion mediated by cadherin cell-cell junction assembly homophilic cell adhesion via plasma membrane adhesion molecules regulation of gene expression synapse assembly adherens j... |
post-translational protein modification protein N-linked glycosylation via asparagine | oligosaccharyltransferase III complex | dolichyl-diphosphooligosaccharide-protein glycotransferase activity metal ion binding | Canis lupus familiaris | 3D-structure Endoplasmic reticulum Glycoprotein Glycosyltransferase Magnesium Manganese Membrane Metal-binding Reference proteome Transferase Transmembrane Transmembrane helix | MTKLGFLRLS | MTKLGFLRLSYEKQDTLLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDPYFNYRTTRFLAEEGFYKFHNWFDDRAWYPLGRIIGGTIYPGLMITSAAIYHVLHFFHITIDIRNVCVFLAPLFSSFTTIVTYHLTKELKDAGAGLLAAAMIAVVPGYISRSVAGSYDNEGIAIFCMLLTYYMWIKAVKTGSIYWAAKCALAYFYMVSSWGGYVFLINLIPLHVLVLMLTGRFSHRIYVAYCTVYCLGTILSMQISFVGFQPVLSSEHMAAFGVFGLCQIHAFVDYLRSKLNPQQFEVLFRSVISLVGFVLLTVGALLMLT... | post-translational protein modification protein N-linked glycosylation via asparagine oligosaccharyltransferase III complex dolichyl-diphosphooligosaccharide-protein glycotransferase activity metal ion binding Canis lupus familiaris 3D-structure Endoplasmic reticulum Glycoprotein Glycosyltransferase Magnesium Manganes... |
DNA dealkylation involved in DNA repair oxidative single-stranded DNA demethylation oxidative single-stranded RNA demethylation regulation of multicellular organism growth RNA repair | cytoplasm; nuclear speck | DNA-N1-methyladenine dioxygenase activity ferrous iron binding mRNA N6-methyladenosine dioxygenase activity oxidative DNA demethylase activity transferase activity | Canis lupus familiaris | Acetylation Cytoplasm Dioxygenase Iron Metal-binding Nucleus Oxidoreductase Phosphoprotein Reference proteome Transferase | MKRTPTAEER | MKRTPTAEEREREAKKLRLLEELEDTWLPYLTPKDDEFYQQWQLKYPKLILREAGSVPEDLHKEVQEAFLTLHKHGCFFRDLVRIQGKDLLTPVSRILIGNPGCTYKYLNTRLFTVPWPVKGASTKYDEAGIAAACQTFLKLNDYLQIETIQALEELACKEKSNIDAVPVCIGPDFPRVGMGSFDGQDELDIKNRAAYNVTLLNFMDPQKMPYLKEEPYFGMGKMAVSWHHDENLVERSAVAVYSYSCEGPEEESEDDPQLEGRDPDTWHVGFKISWDIETPGLAIPLHQGDCYFMLDDLNATHQHCVLAGLPPRFSSTH... | DNA dealkylation involved in DNA repair oxidative single-stranded DNA demethylation oxidative single-stranded RNA demethylation regulation of multicellular organism growth RNA repair cytoplasm; nuclear speck DNA-N1-methyladenine dioxygenase activity ferrous iron binding mRNA N6-methyladenosine dioxygenase activity oxid... |
actin filament organization early endosome to recycling endosome transport endocytosis protein transport vesicle transport along actin filament | actin cytoskeleton; axon; brush border; cell cortex; cytoplasm; cytosol; dendrite; early endosome; endosome; microvillus; myelin sheath; myosin complex; perikaryon; plasma membrane; vesicle | actin filament binding ATP binding calmodulin binding microfilament motor activity protein domain specific binding | Canis lupus familiaris | Acetylation Actin-binding ATP-binding Calmodulin-binding Cell projection Cytoplasm Endocytosis Endosome Motor protein Myosin Nucleotide-binding Phosphoprotein Protein transport Reference proteome Repeat Transport | MAEQESLEFG | MAEQESLEFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKALNIYGRDTIEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFKVVADAMKVIGFKPEETQTVYKILAAILHLGNLKFMVDGDTPLIENGKVVSIIAELLSTKTDMVEKALLYRTV... | actin filament organization early endosome to recycling endosome transport endocytosis protein transport vesicle transport along actin filament actin cytoskeleton; axon; brush border; cell cortex; cytoplasm; cytosol; dendrite; early endosome; endosome; microvillus; myelin sheath; myosin complex; perikaryon; plasma memb... |
bicellular tight junction assembly cellular response to insulin stimulus cortical actin cytoskeleton organization endocytic recycling endothelial cell chemotaxis establishment of Sertoli cell barrier Golgi vesicle fusion to target membrane neuron projection development protein kinase A signaling protein localization to... | bicellular tight junction; cytoplasmic vesicle; endocytic vesicle; endosome; insulin-responsive compartment; lamellipodium; lateral plasma membrane; neuron projection; plasma membrane; recycling endosome; recycling endosome membrane; synaptic vesicle; trans-Golgi network; trans-Golgi network transport vesicle | GTP binding GTPase activity | Canis lupus familiaris | Cell junction Cell membrane Cell projection Cytoplasmic vesicle Endosome Golgi apparatus GTP-binding Lipoprotein Membrane Methylation Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Tight junction Transport | MAKAYDHLFK | MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDSFNNTYISTIGIDFKIRTVDVEGKKIKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKRKVQKEQAIKLAREHGIRFFETSAKSSTNVDEAFSSLARDILLKSGGRRSGNSHKAPGTDLKPCDKKNTSKCSLG | bicellular tight junction assembly cellular response to insulin stimulus cortical actin cytoskeleton organization endocytic recycling endothelial cell chemotaxis establishment of Sertoli cell barrier Golgi vesicle fusion to target membrane neuron projection development protein kinase A signaling protein localization to... |
cilium assembly microtubule bundle formation regulation of protein localization to cilium retina homeostasis | centriolar satellite; centrosome; ciliary basal body; cilium; cytoplasm; microtubule; photoreceptor inner segment; photoreceptor outer segment | microtubule binding protein homodimerization activity | Canis lupus familiaris | Cell projection Cilium Cilium biogenesis/degradation Coiled coil Cytoplasm Cytoskeleton Disulfide bond Reference proteome | MGSKNKIAKC | MGSKNKIAKCPIRTKQTGYILKSTQNTCIRSGKLLQKKRMGSETSLAKGEKSSMIFSPTKDLCKQYVDKDCLYVQKEISPATPTIQKTRNTINTSVVAKQKHCKKHITAENTKSGLVCLTQDQLQQILMTVNQGNKSISAIENGKEETSQDSLHLNNTSNQPKDENIMGFQKNEALSSVLDENKSTLNKNQETSKQYEQKIAIENVWKPADIFSTLGERERDRSLLEAKKAQWKKELDEQVALKKKEKEASEKWNNPWKKFESDKIVWEKFQTLGQSKTSLSSSNILSQSPSQITVVQADDYPLCRASQILEETVPLERP... | cilium assembly microtubule bundle formation regulation of protein localization to cilium retina homeostasis centriolar satellite; centrosome; ciliary basal body; cilium; cytoplasm; microtubule; photoreceptor inner segment; photoreceptor outer segment microtubule binding protein homodimerization activity Canis lupus fa... |
developmental pigmentation hematopoietic stem cell differentiation hemopoiesis muscle cell development positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II sclerotome development skeletal system development somite development | cytoplasm; nucleus | chromatin binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding | Danio rerio | Activator Alternative splicing Cytoplasm Developmental protein DNA-binding Homeobox Nucleus Reference proteome Repressor Transcription Transcription regulation | MEQSASSCMR | MEQSASSCMRSPHTGGALWGCVRSPHSGGSGAGIQPYQQAPFALHQKHDFLAYTDFSSSCLVPAPHAYPREDRLYPETHSGYQRTEWQFSPCEPRGRGQEPCQGAAEAVGAEMDSAGGDRLAGAVTGCLEGDYSPQSVPAVDTEKKSSKRKREVTDIQDSSFKADSNCKARKERTAFTKEQLRELEAEFTHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKRVKGGQPASPHDLEADELDSAASPSSE | developmental pigmentation hematopoietic stem cell differentiation hemopoiesis muscle cell development positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II sclerotome development skeletal system development somite development cytoplasm; nucleus chromatin binding DNA... |
cilium assembly heart looping intracellular protein transport Kupffer's vesicle development left/right axis specification protein localization to centrosome protein localization to cilium vesicle organization | centrosome; endosome; endosome membrane | phosphatidylinositol phosphate binding | Danio rerio | Alternative splicing Cilium biogenesis/degradation Cytoplasm Cytoskeleton Endosome Lipid-binding Membrane Protein transport Reference proteome Transport | MDNTSFEKRE | MDNTSFEKREFISVWVRDPQVHKEDFWHTYISYEICLHTNSMCFRKKTSCVRRRYSEFVWLRHKLQDNALLIELPKLPPWNPFFNLNNEFHITQRMQGLQQFLEAVLQTPLLLSDSRLHLFLQSQLSIAKMDACAQGHTHYTVAQAIQRCGGEARFPVEEQHQEDSKTCCDSDCDSTTSSGLGCSIEPATLVEQDLSHNERFAHEFQATNPEAELCSSLSSSPHGHSVI | cilium assembly heart looping intracellular protein transport Kupffer's vesicle development left/right axis specification protein localization to centrosome protein localization to cilium vesicle organization centrosome; endosome; endosome membrane phosphatidylinositol phosphate binding Danio rerio Alternative splicin... |
protein palmitoylation protein targeting to membrane synaptic vesicle maturation | endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; Golgi apparatus; Golgi membrane; perinuclear region of cytoplasm; plasma membrane | metal ion binding protein-cysteine S-myristoyltransferase activity protein-cysteine S-palmitoyltransferase activity protein-cysteine S-stearoyltransferase activity | Danio rerio | Acyltransferase Cell membrane Cytoplasm Endoplasmic reticulum Golgi apparatus Lipoprotein Membrane Metal-binding Palmitate Phosphoprotein Reference proteome Transferase Transmembrane Transmembrane helix Zinc | MAPSHAVRCC | MAPSHAVRCCQRGLSWIPVIFINLVVCWSYYAYVVELCIYTIPNVNEQVIYLVVFHAFFFMFMWSYWKTISSKPTNPSKEFCLPKAEKELYEKEERPEAQQDILKRVARELPIYTFTGSGAIRYCDRCQLIKPDRCHHCSTCDKCVLKMDHHCPWVNNCVGFSNYKFFVLFLAYSMLYCVYIAATVLQYFIKFWTNQLPDTHAKFHVLFLFFVAAMFFISILSLFSYHLWLVGKNRTTIEAFRAPVFRNGPDKNGFTLGFRKNITQVFGDQKKYWCLPIFSSLGDGYTFPTRLVTVDVEHGNIEHQTIKCTVDGQTNARP... | protein palmitoylation protein targeting to membrane synaptic vesicle maturation endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; Golgi apparatus; Golgi membrane; perinuclear region of cytoplasm; plasma membrane metal ion binding protein-cysteine S-my... |
double-strand break repair via synthesis-dependent strand annealing reciprocal meiotic recombination | nucleus | ATP binding ATP-dependent activity, acting on DNA ATP-dependent chromatin remodeler activity DNA binding DNA translocase activity helicase activity hydrolase activity | Danio rerio | 3D-structure ATP-binding Helicase Hydrolase Nucleotide-binding Phosphoprotein Reference proteome | MRRSLAPSQV | MRRSLAPSQVAKRKQGPDSDDEEDWEPDMEPQCKRDCREKYISPYRKPLTPLTNRPFCADGNEHEAFIRKILSKPFKIPIPNYTGVLGLRALGLRRAGVRKALHDPFEDGALVLYEPPVISAHDLIKADKEKLPVHVVVDPVLSKVLRPHQREGVKFLWDCVTGRRIENSYGCIMADEMGLGKTLQCITLIWTLLKQSPDCKPEIDKVIVVSPSSLVRNWYNEVGKWLGGRVQPVAIDGGSKDEIDSKLVNFISQQGMRIPTPILIISYETFRLHAEVLHKGKVGLVICDEGHRLKNSDNQTYLALNSMNAQRRVLISGT... | double-strand break repair via synthesis-dependent strand annealing reciprocal meiotic recombination nucleus ATP binding ATP-dependent activity, acting on DNA ATP-dependent chromatin remodeler activity DNA binding DNA translocase activity helicase activity hydrolase activity Danio rerio 3D-structure ATP-binding Helica... |
angiogenesis cardiac muscle tissue morphogenesis cell migration cell-matrix adhesion cytoskeleton organization integrin-mediated signaling pathway regulation of cell shape Wnt signaling pathway | cell cortex; cell surface; extrinsic component of cytoplasmic side of plasma membrane; focal adhesion; I band; intercalated disc; lamellipodium membrane; nucleus; stress fiber | integrin binding lipid binding | Danio rerio | Cell adhesion Cell junction Cell membrane Cell projection Cell shape Cytoplasm Cytoskeleton Lipid-binding Membrane Nucleus Reference proteome Wnt signaling pathway | MALDGIRMPD | MALDGIRMPDGCYADGTWELKMHVTDLNRDVSLRVTGEIHIGGVMLKLVEKLDVKKDWSDHALWWEKKKTWLLKTHWTLDKYGIQADARLLFTPQHKLLRLQLPNMKHMRVKVNFSDRVFKAVSDICKTFNIRHPEELSLLRKPRDPKKKKKKLEDAEEETLELEGPLLTPGSGSIYSSPGLYSKTMTPTYDSRDGSPLSPTSAWFGDSPLSEGNPSILAVSQPITSPDILVKMYKPQSLLDKAKINQGWLDSSRSLMEQDVKENEVLLLRFKYHSFFDLNPKYDAIRVNQLYEQAKWAILLEEIECTEEEMMMFAALQY... | angiogenesis cardiac muscle tissue morphogenesis cell migration cell-matrix adhesion cytoskeleton organization integrin-mediated signaling pathway regulation of cell shape Wnt signaling pathway cell cortex; cell surface; extrinsic component of cytoplasmic side of plasma membrane; focal adhesion; I band; intercalated di... |
determination of heart left/right asymmetry heart looping photoreceptor cell development photoreceptor cell maintenance photoreceptor cell outer segment organization post-Golgi vesicle-mediated transport pronephros development protein transport retina development in camera-type eye retina layer formation | cilium; periciliary membrane compartment | GTP binding GTPase activator activity | Danio rerio | Cell membrane Cell projection GTP-binding GTPase activation Lipoprotein Membrane Myristate Nucleotide-binding Palmitate Protein transport Reference proteome Transport | MGCFFSKKSR | MGCFFSKKSRRKSPKKDAALPTGDESATGNDLAETNNTALGSNSNQEAPKQYSWDKREKVDPKDFMLTGLKNETVGRLPGKLNGQQFVIQDCENCNIFVLDHSATITIDDCVNCRIVLGPVKGSVFFRDCKDIKCVVACQQFRTRDCKKMDVFLCCATQPIIESSTGMKFGCFQYYYPELAFHFKDAGLSIFNNNWSNIHDFTPVSGETNWSLLPEDAVVLDHVPLPDPESEFKSVRIATEAGRSIVPLTKGSRRTESEESCLFVFFAGDYTTANARKLIDEATAKGFVLIQTKEVSMRPEDVSRVFQNNAESLTEWITK... | determination of heart left/right asymmetry heart looping photoreceptor cell development photoreceptor cell maintenance photoreceptor cell outer segment organization post-Golgi vesicle-mediated transport pronephros development protein transport retina development in camera-type eye retina layer formation cilium; perici... |
cardiolipin acyl-chain remodeling cardiolipin metabolic process heart development heart looping inner mitochondrial membrane organization mitophagy positive regulation of heart contraction | mitochondrial inner membrane; mitochondrial membrane; mitochondrial outer membrane; mitochondrion | 1-acylglycerophosphocholine O-acyltransferase activity | Danio rerio | Acyltransferase Lipid metabolism Membrane Mitochondrion Mitochondrion inner membrane Mitochondrion outer membrane Reference proteome Transferase | MPLEVTWPFP | MPLEVTWPFPQCPRLGWRISSRVVMGMVGSYSYLWTKYFNSLMVHNQDVLLNLVDERPQDTPLITVCNHQSCMDDPHIWGVLKFRQLWNLNKMRWTPTASDICFTREFHSSFFSRGKCVPVVRGDGVYQKGMDFLLERLNQGEWIHIFPEGRVNMSGEFMRIKWGIGRLIAECSLHPIILPMWHIGMNDVLPNETPYIPRVGQRITVLVGKPFTVRHLVNALRAENTNPTEMRKTVTDYIQDEFRSLKAQAEALHHRLQNHT | cardiolipin acyl-chain remodeling cardiolipin metabolic process heart development heart looping inner mitochondrial membrane organization mitophagy positive regulation of heart contraction mitochondrial inner membrane; mitochondrial membrane; mitochondrial outer membrane; mitochondrion 1-acylglycerophosphocholine O-acy... |
homologous recombination macroautophagy negative regulation of transcription by RNA polymerase II polyamine deacetylation regulation of tubulin deacetylation spermidine deacetylation swimming behavior | cytoplasm; nucleus | acetylputrescine deacetylase activity acetylspermidine deacetylase activity deacetylase activity zinc ion binding | Danio rerio | 3D-structure Cytoplasm Hydrolase Metal-binding Nucleus Reference proteome Zinc | MASGSALIFD | MASGSALIFDEEMSRYKLLWTDPACEIEVPERLTVSYEALRTHGLAQRCKAVPVRQATEQEILLAHSEEYLEAVKQTPGMNVEELMAFSKKYNDVYFHQNIYHCAKLAAGATLQLVDSVMKREVRNGMALVRPPGHHSQRSAANGFCVFNNVAIAALYAKKNYNLNRILIVDWDVHHGQGIQYCFEEDPSVLYFSWHRYEHQSFWPNLPESDYSSVGKGKGSGFNINLPWNKVGMTNSDYLAAFFHVLLPVAYEFDPELVIVSAGFDSAIGDPEGEMCALPEIFAHLTHLLMPLAAGKMCVVLEGGYNLTSLGQSVCQTV... | homologous recombination macroautophagy negative regulation of transcription by RNA polymerase II polyamine deacetylation regulation of tubulin deacetylation spermidine deacetylation swimming behavior cytoplasm; nucleus acetylputrescine deacetylase activity acetylspermidine deacetylase activity deacetylase activity zin... |
cerebrospinal fluid circulation cilium assembly determination of left/right symmetry epithelial cilium movement involved in extracellular fluid movement heart jogging heart looping Kupffer's vesicle development regulation of cilium beat frequency involved in ciliary motility regulation of transcription by RNA polymeras... | extracellular region; nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding | Danio rerio | Activator Cilium biogenesis/degradation DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MLSMSSMDPW | MLSMSSMDPWPEGSVGLEEEVVTAAAQAERLDTSTPLQCNTSLDSDNLDDSLTSLQWLQEFSILNASTGQHTSPSSHSHLMGSDAPSSPLAGDPASIGMPLTPGKPTAASFCRVPMFSALPSLVAHGHCPDEVDYKSNPHIKPPYSYATLICMAMQASKKTKITLSCIYKWITDNFCYFRHADPTWQNSIRHNLSLNKCFIKVPRQKDEPGKGGFWKIDPQYAERLLNGAYKKRRLPPVQINPALQHRLRMNAQATGVISRNLSVSPESQQLLKDFEEATSADQNWDPRLAEATMLSCWISGKGTNKRKQPYNHRTGKTP... | cerebrospinal fluid circulation cilium assembly determination of left/right symmetry epithelial cilium movement involved in extracellular fluid movement heart jogging heart looping Kupffer's vesicle development regulation of cilium beat frequency involved in ciliary motility regulation of transcription by RNA polymeras... |
ceramide biosynthetic process glycosphingolipid metabolic process sphingomyelin catabolic process sphingomyelin metabolic process | cytoplasm; endoplasmic reticulum membrane; extracellular region; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial membrane | metal ion binding phospholipase activity sphingomyelin phosphodiesterase activity | Danio rerio | Endoplasmic reticulum Hydrolase Lipid metabolism Magnesium Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Reference proteome Signal-anchor Sphingolipid metabolism Transit peptide Transmembrane Transmembrane helix | MSLRESPFPN | MSLRESPFPNGFLEGLHAVGWGLIFPCFWFLDRLIAVCISTTLERMWRLEQECYLHPLKVVFGSILFFILFVISTPFALLGFILWAPLQAIRRPFSYHKQEQSIPMENRNARWEEMGKISFGFLTANVCLLPDGIARFNNLGHTQKRALIIGKSIVQGVTRPHIRIFVDSPSSCGTVTPSSSLIPQPNASSYGSVDASGELPDAIEVNEITPKPNCNQNSNHQKHPPRSLRTLLRDADIPMEVSALFPPSVDIVCLQEVFDKRAARKLTQALGPLYGHVLYDVGVYACHPAGSCSSFKFFNSGLFLASRFPIMEAEYRCF... | ceramide biosynthetic process glycosphingolipid metabolic process sphingomyelin catabolic process sphingomyelin metabolic process cytoplasm; endoplasmic reticulum membrane; extracellular region; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial membrane metal ion binding phospholipase activ... |
canonical Wnt signaling pathway cell adhesion cell-cell adhesion convergent extension determination of dorsal/ventral asymmetry dorsal/ventral pattern formation ectoderm development embryonic axis specification glomerular filtration liver development positive regulation of transcription by RNA polymerase II positive re... | adherens junction; catenin complex; cell cortex; cytoplasm; intercalated disc; membrane; microvillus; nucleus; plasma membrane; zonula adherens | alpha-catenin binding cadherin binding DNA-binding transcription factor binding protein phosphatase binding transcription coactivator activity | Danio rerio | 3D-structure Activator Cell membrane Cytoplasm Membrane Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Ubl conjugation Wnt signaling pathway | MATQSDLMEL | MATQSDLMELEMAMDPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEDDDVDNQVLYEWEQGFNQSFNQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDSAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTSGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGP... | canonical Wnt signaling pathway cell adhesion cell-cell adhesion convergent extension determination of dorsal/ventral asymmetry dorsal/ventral pattern formation ectoderm development embryonic axis specification glomerular filtration liver development positive regulation of transcription by RNA polymerase II positive re... |
apoptotic process cell cycle cell population proliferation erythrocyte development hemopoiesis intracellular signal transduction neural precursor cell proliferation positive regulation of apoptotic process protein autophosphorylation regulation of heart contraction | cell cortex; cytoplasm; plasma membrane | ATP binding calcium ion binding lipid binding non-membrane spanning protein tyrosine kinase activity protein serine kinase activity protein serine/threonine kinase activity | Danio rerio | Apoptosis ATP-binding Cell cycle Cell membrane Kinase Lipid-binding Membrane Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MPVDSTSELL | MPVDSTSELLKHYEVYETIGSGGFAKVKLGRHKLTGEKVAIKIMEKKDLGDDLPRVKIEIEAMKNLSHQHVCRLYHVIETTSKIYMVLEYCPGGELFDYIIAKDRLSEEETRVFFRQIISALAYVHSQGYAHRDLKPENLLIDEDHNLKLIDFGLCAKPKGGLGFELLTCCGSPAYAAPELIQGKAYIGSEADVWSMGVLLYALLCGFLPFDDDNCMVLYRKITRGKYSNPHWLSPSSILLLNQMMQVDPKRRLTVKHLLDHPWVMRGYSTPVEWHSKYPLGHIDEDCITEMAVTFKQSKQRTIQLVSEWKYDQITATYL... | apoptotic process cell cycle cell population proliferation erythrocyte development hemopoiesis intracellular signal transduction neural precursor cell proliferation positive regulation of apoptotic process protein autophosphorylation regulation of heart contraction cell cortex; cytoplasm; plasma membrane ATP binding ca... |
erythrocyte maturation regulation of gene expression regulation of neurogenesis Wnt signaling pathway involved in dorsal/ventral axis specification | cytoplasm; nucleus | beta-catenin binding DNA binding metal ion binding | Danio rerio | DNA-binding Homeobox Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Zinc Zinc-finger | MFQLPVNNLT | MFQLPVNNLTRLRKARKKVKRLLSDIGLDYCKEHVEDYKDVDPDDSDDSNESHLDLCTWDPTWTKSQDYRTKQFCCSDCPFASKYFSAYKNHFRNVHREDFESRILLNCSYCTYSGNKRTLETHVRLFHMPHNVMRQGVVGPHGAPVGAKDGMRVDKPMLGDRKELPVYYCKKCTYRDRLYNVVRRHIYREHFQHVATPYLGKNSEKQVNSGEAQANSHGIHCKSCHFTPRSYEALVQHVIEFHERIGHQVTAMIGHTNVIVPRLQTNPIQRGVPITSGVRPQTPQMNRFSMPKVVGLPVGNHFKQSLAGNSVPGQPVRV... | erythrocyte maturation regulation of gene expression regulation of neurogenesis Wnt signaling pathway involved in dorsal/ventral axis specification cytoplasm; nucleus beta-catenin binding DNA binding metal ion binding Danio rerio DNA-binding Homeobox Metal-binding Nucleus Reference proteome Repeat Transcription Transc... |
cortisol metabolic process glucocorticoid metabolic process multicellular organismal response to stress | intracellular membrane-bounded organelle; membrane | 11-beta-hydroxysteroid dehydrogenase (NAD+) activity | Danio rerio | Lipid metabolism Membrane Oxidoreductase Reference proteome Steroid metabolism Transmembrane Transmembrane helix | MEDFAVSFWI | MEDFAVSFWIYIGVMSIFVGGAVKKFLAFNIGAMPSVVVWLGATLLVERLCALCMPAVLARLVLCVCCWLYFTWATPKPSLPVEDKAVFITGCDSGFGNATAKKLDAMGFEVFATVLNLEGEGAKHLRKVCSSRLTLLQVDITQPQQVQQALLDTKAKLGIRDLWGLVNNAGWCVNIGDAELSLMSNYRGCMEVNFFGTVTVTRTFLPLLRQSKGRIVTISSPSGEHPFPCLASYGASKAALNLFINTLRHELDPWGVKVSTILPSAYKTGQSSNAEYWEKQYKSLLQGLSPNLLEEYGEEYLLETKELFQNYAKTANED... | cortisol metabolic process glucocorticoid metabolic process multicellular organismal response to stress intracellular membrane-bounded organelle; membrane 11-beta-hydroxysteroid dehydrogenase (NAD+) activity Danio rerio Lipid metabolism Membrane Oxidoreductase Reference proteome Steroid metabolism Transmembrane Transm... |
dentate gyrus development heart development mRNA destabilization muscle cell development negative regulation of inflammatory response negative regulation of long-term synaptic potentiation negative regulation of translation negative regulation of tumor necrosis factor production non-membrane-bounded organelle assembly ... | axon; cytoplasmic ribonucleoprotein granule; dendritic filopodium; dendritic spine; dendritic spine neck; growth cone; intracellular non-membrane-bounded organelle; membrane; neuronal cell body; nucleus; polysome; postsynaptic density; presynapse | molecular condensate scaffold activity mRNA 3'-UTR AU-rich region binding mRNA 3'-UTR binding mRNA binding protein homodimerization activity translation regulator activity | Danio rerio | Alternative splicing Cytoplasm Myogenesis Phosphoprotein Reference proteome Repeat RNA-binding | MEELTVEVRG | MEELTVEVRGSNGAYYKGFVRDVHDDSLSISFENNWQPERQVPFSDVRLPPSADTKKEIGEGEEVEIFSRANEQEPCGWWLAKVRMMKGDFYVIEYAACDATYNEIVTFERLRPVNRNKAVTESTFFRCSVPVPEDLRAACESEQAHKEFKKAVGAIRIVYSPEKSELVVLSLSEATVKRVSLLSDIHLRSIRTKLMLMSRNQEATKHLESTKQLASAFQEEFTVREDLMGLAIGSHGSNIQQARKVPGVTAIELEEETGTFRIYGESTEAVQKARNYLEFLEDSVQIPRNLVGKVIGKNGKVIQEIVDKSGVVRVRIEG... | dentate gyrus development heart development mRNA destabilization muscle cell development negative regulation of inflammatory response negative regulation of long-term synaptic potentiation negative regulation of translation negative regulation of tumor necrosis factor production non-membrane-bounded organelle assembly ... |
positive regulation of gene expression regulation of gene expression regulation of transcription by RNA polymerase II rhythmic process | nucleus | nuclear receptor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding zinc ion binding | Danio rerio | Activator Biological rhythms Developmental protein DNA-binding Metal-binding Nucleus Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MMYFVISAMK | MMYFVISAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNAAYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRLQQQQRDHQQQPGEAEPLTPTYGLSTNGLTELHDDLSGYMNGHTPDGTKPDSGVSSFYLDIQPSPDQSGLDINGIKPEPICDFTPGSGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHMETCQYLREELQQMTWQAFLQEEVENYQSKPREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFVRMCRAFDPQ... | positive regulation of gene expression regulation of gene expression regulation of transcription by RNA polymerase II rhythmic process nucleus nuclear receptor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding zinc ion binding Danio rerio Activator Biological rhythms Developmental protein ... |
cilium assembly inner ear development microtubule-based movement neuromast development nose development opsin transport photoreceptor cell development photoreceptor cell differentiation photoreceptor cell outer segment organization pronephros development retina development in camera-type eye retina morphogenesis in cam... | cilium; cytoplasm; dendritic spine; kinesin complex; microtubule | ATP binding ATP hydrolysis activity microtubule binding microtubule motor activity | Danio rerio | ATP-binding Cell projection Cilium biogenesis/degradation Coiled coil Cytoplasm Cytoskeleton Microtubule Motor protein Nucleotide-binding Reference proteome Synapse | MSKSKSSESV | MSKSKSSESVKVVVRCRPMNEKERVANFNRVVSVDVKLGQVAVCNPRGASSHEHPKVFTFDSVYDWNSKQMELYDETFRPLVDSVLFGFNGTIFAYGQTGTGKTYTMEGVRNDPERRGVIPNSFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQARRLELKERPDTGVYVKDLSSFVTKSVREIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSELGPDGENHIRVGKLNLVDLAGSERQTKTGAQGERLKEATKINLSLSALGNVISALVDGRSTHIPYRDSKLTRLLQDSLGGNARTVMVANIGP... | cilium assembly inner ear development microtubule-based movement neuromast development nose development opsin transport photoreceptor cell development photoreceptor cell differentiation photoreceptor cell outer segment organization pronephros development retina development in camera-type eye retina morphogenesis in cam... |
axoneme assembly cilium movement involved in otolith formation flagellated sperm motility muscle cell development otolith tethering positive regulation of protein localization to cilium positive regulation of smoothened signaling pathway | ciliary basal body; cytoplasm; extracellular region; Golgi apparatus; microtubule; motile cilium | microtubule binding small GTPase binding | Danio rerio | Cell projection Cilium Coiled coil Cytoplasm Cytoskeleton Flagellum Golgi apparatus Microtubule Reference proteome | MPPKRKSSPK | MPPKRKSSPKGKTPTVVDGLSTEEMSKEQLEEHIMRLREELDREREERNYFQLERDKIHTFWEITRRHLEENKCELRNRERELEEVEERHQVEIKVYKQKVKHLLYEQQNMLSELKAESIISTKLLQDEHADLEKEQWKDMRSLKLELKQQELSSENVLKRIHLKHDEETTDLRNDFARQVQEIGSKYEKRMQKLRQEEELRRKTEIHEIEERKNTHINMLMKNHEKAFRDIRNYFSDIVYKNLDLITSLKEELKEMKKNEEKRNKEMAEVLEQNKELKESSQKAKEQVAELQKQLANYEKDKSILTRSRARLKMSDREM... | axoneme assembly cilium movement involved in otolith formation flagellated sperm motility muscle cell development otolith tethering positive regulation of protein localization to cilium positive regulation of smoothened signaling pathway ciliary basal body; cytoplasm; extracellular region; Golgi apparatus; microtubule;... |
collagen fibril organization endothelial cell migration endothelial cell proliferation epithelial to mesenchymal transition heterochromatin organization negative regulation of DNA-templated transcription negative regulation of stem cell population maintenance negative regulation of transcription by RNA polymerase II pe... | basement membrane; chromatin; collagen-containing extracellular matrix; endoplasmic reticulum; extracellular space; membrane; nucleus | calcium ion binding copper ion binding protein-lysine 6-oxidase activity | Danio rerio | Basement membrane Calcium Chromatin regulator Chromosome Copper Disulfide bond Endoplasmic reticulum Extracellular matrix Glycoprotein LTQ Metal-binding Nucleus Oxidoreductase Reference proteome Repeat Repressor Secreted Signal TPQ Transcription Transcription regulation | MAVSSALCIF | MAVSSALCIFSLLVLAQAQSELQQPKIELRLAGDKRKHYEGRLEVFYNNEWGTVCDDDFSIEAAHVACRQLGFLGAVAWSPSAKFGQGEGRIWLDNVHCTGRENSLAACPSNGFGVSDCRHSEDVGVICNQKRIPGHRFINIMNNNVETLEERVEEIRIRPISSHLKRIPITEGYVEVKERGKWRQICDEEWTPLNSRVACGMYGFPGEKNYNNKVYRSLSMRKKKNYWGFSVNCTGNEAHVSSCRLGKALEPKRNGTCGRGLPVVVSCVPGRAFAPSSSIGFRKAYRPEQPLVRLRGGANVGEGRVEVLKNGVWGTVCD... | collagen fibril organization endothelial cell migration endothelial cell proliferation epithelial to mesenchymal transition heterochromatin organization negative regulation of DNA-templated transcription negative regulation of stem cell population maintenance negative regulation of transcription by RNA polymerase II pe... |
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