Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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cell wall organization cell wall organization or biogenesis proteolysis | extracellular region; peptidoglycan-based cell wall | cysteine-type peptidase activity N-acetylmuramoyl-L-alanine amidase activity | Mycobacterium tuberculosis | 3D-structure Cell wall biogenesis/degradation Hydrolase Protease Reference proteome Secreted Signal Thiol protease | MRRNRRGSPA | MRRNRRGSPARPAARFVRPAIPSALSVALLVCTPGLATADPQTDTIAALIADVAKANQRLQDLSDEVQAEQESVNKAMVDVETARDNAAAAEDDLEVSQRAVKDANAAIAAAQHRFDTFAAATYMNGPSVSYLSASSPDEIIATVTAAKTLSASSQAVMANLQRARTERVNTESAARLAKQKADKAAADAKASQDAAVAALTETRRKFDEQREEVQRLAAERDAAQARLQAARLVAWSSEGGQGAPPFRMWDPGSGPAGGRAWDGLWDPTLPMIPSANIPGDPIAVVNQVLGISATSAQVTANMGRKFLEQLGILQPTDT... | cell wall organization cell wall organization or biogenesis proteolysis extracellular region; peptidoglycan-based cell wall cysteine-type peptidase activity N-acetylmuramoyl-L-alanine amidase activity Mycobacterium tuberculosis 3D-structure Cell wall biogenesis/degradation Hydrolase Protease Reference proteome Secreted... |
negative regulation of gene expression positive regulation of gene expression quorum sensing regulation of cell population proliferation | extracellular region | hydrolase activity | Mycobacterium tuberculosis | 3D-structure Hydrolase Reference proteome Signal Virulence | MKNARTTLIA | MKNARTTLIAAAIAGTLVTTSPAGIANADDAGLDPNAAAGPDAVGFDPNLPPAPDAAPVDTPPAPEDAGFDPNLPPPLAPDFLSPPAEEAPPVPVAYSVNWDAIAQCESGGNWSINTGNGYYGGLRFTAGTWRANGGSGSAANASREEQIRVAENVLRSQGIRAWPVCGRRG | negative regulation of gene expression positive regulation of gene expression quorum sensing regulation of cell population proliferation extracellular region hydrolase activity Mycobacterium tuberculosis 3D-structure Hydrolase Reference proteome Signal Virulence MKNARTTLIA MKNARTTLIAAAIAGTLVTTSPAGIANADDAGLDPNAAAGPDAVGF... |
tricarboxylic acid cycle | cytosol; peptidoglycan-based cell wall | 2-oxoglutarate synthase activity magnesium ion binding thiamine pyrophosphate binding | Mycobacterium tuberculosis | Magnesium Oxidoreductase Reference proteome Tricarboxylic acid cycle | MTRSGDEAQL | MTRSGDEAQLMTGVTGDLAGTELGLTPSLTKNAGVPTTDQPQKGKDFTSDQEVRWCPGCGDYVILNTIRNFLPELGLRRENIVFISGIGCSSRFPYYLETYGFHSIHGRAPAIATGLALAREDLSVWVVTGDGDALSIGGNHLIHALRRNINVTILLFNNRIYGLTKGQYSPTSEVGKVTKSTPMGSLDHPFNPVSLALGAEATFVGRALDSDRNGLTEVLRAAAQHRGAALVEILQDCPIFNDGSFDALRKEGAEERVIKVRHGEPIVFGANGEYCVVKSGFGLEVAKTADVAIDEIIVHDAQVDDPAYAFALSRLSDQ... | tricarboxylic acid cycle cytosol; peptidoglycan-based cell wall 2-oxoglutarate synthase activity magnesium ion binding thiamine pyrophosphate binding Mycobacterium tuberculosis Magnesium Oxidoreductase Reference proteome Tricarboxylic acid cycle MTRSGDEAQL MTRSGDEAQLMTGVTGDLAGTELGLTPSLTKNAGVPTTDQPQKGKDFTSDQEVRWCPGCGDYV... |
cell wall organization peptidoglycan biosynthetic process peptidoglycan metabolic process peptidoglycan-based cell wall biogenesis regulation of cell shape | peptidoglycan-based cell wall; plasma membrane | acyltransferase activity metal ion binding peptidoglycan L,D-transpeptidase activity | Mycobacterium tuberculosis | 3D-structure Acyltransferase Calcium Cell membrane Cell shape Cell wall biogenesis/degradation Lipoprotein Membrane Metal-binding Palmitate Peptidoglycan synthesis Reference proteome Signal Transferase Virulence | MPKVGIAAQA | MPKVGIAAQAGRTRVRRAWLTALMMTAVMIGAVACGSGRGPAPIKVIADKGTPFADLLVPKLTASVTDGAVGVTVDAPVSVTAADGVLAAVTMVNDNGRPVAGRLSPDGLRWSTTEQLGYNRRYTLNATALGLGGAATRQLTFQTSSPAHLTMPYVMPGDGEVVGVGEPVAIRFDENIADRGAAEKAIKITTNPPVEGAFYWLNNREVRWRPEHFWKPGTAVDVAVNTYGVDLGEGMFGEDNVQTHFTIGDEVIATADDNTKILTVRVNGEVVKSMPTSMGKDSTPTANGIYIVGSRYKHIIMDSSTYGVPVNSPNGYRT... | cell wall organization peptidoglycan biosynthetic process peptidoglycan metabolic process peptidoglycan-based cell wall biogenesis regulation of cell shape peptidoglycan-based cell wall; plasma membrane acyltransferase activity metal ion binding peptidoglycan L,D-transpeptidase activity Mycobacterium tuberculosis 3D-st... |
dephosphorylation L-serine biosynthetic process protein dephosphorylation | cytoplasm; extracellular region; host cell cytosol | amino acid binding L-phosphoserine phosphatase activity magnesium ion binding myosin phosphatase activity protein serine/threonine phosphatase activity | Mycobacterium tuberculosis | Amino-acid biosynthesis Host cytoplasm Hydrolase Magnesium Metal-binding Reference proteome Secreted Serine biosynthesis | MPAKVSVLIT | MPAKVSVLITVTGMDQPGVTSALFEVLAQHGVELLNVEQVVIRGRLTLGVLVSCPLDVADGTALRDDVAAAIHGVGLDVAIERSDDLPIIRQPSTHTIFVLGRPITAGAFSAVARGVAALGVNIDFIRGISDYPVTGLELRVSVPPGCVGPLQIALTKVAAEEHVDVAVEDYGLAWRTKRLIVFDVDSTLVQGEVIEMLAARAGAQGQVAAITEAAMRGELDFAESLQRRVATLAGLPATVIDDVAEQLELMPGARTTIRTLRRLGFRCGVVSGGFRRIIEPLARELMLDFVASNELEIVDGILTGRVVGPIVDRPGKAK... | dephosphorylation L-serine biosynthetic process protein dephosphorylation cytoplasm; extracellular region; host cell cytosol amino acid binding L-phosphoserine phosphatase activity magnesium ion binding myosin phosphatase activity protein serine/threonine phosphatase activity Mycobacterium tuberculosis Amino-acid biosy... |
cell redox homeostasis negative regulation of DNA-templated transcription | cytoplasm | 4 iron, 4 sulfur cluster binding dinitrosyl-iron complex binding DNA binding metal ion binding protein-disulfide reductase (NAD(P)) activity | Mycobacterium tuberculosis | 4Fe-4S Chaperone Cytoplasm Disulfide bond DNA-binding Iron Iron-sulfur Metal-binding Phosphoprotein Reference proteome Transcription Transcription regulation | MVPEAPAPFE | MVPEAPAPFEEPLPPEATDQWQDRALCAQTDPEAFFPEKGGSTREAKKICMGCEVRHECLEYALAHDERFGIWGGLSERERRRLKRGII | cell redox homeostasis negative regulation of DNA-templated transcription cytoplasm 4 iron, 4 sulfur cluster binding dinitrosyl-iron complex binding DNA binding metal ion binding protein-disulfide reductase (NAD(P)) activity Mycobacterium tuberculosis 4Fe-4S Chaperone Cytoplasm Disulfide bond DNA-binding Iron Iron-sulf... |
NADP catabolic process phosphatidylinositol phosphate biosynthetic process suppression of host innate immune response | cytoplasm; cytosol; extracellular region; host cell cytoplasmic vesicle; peptidoglycan-based cell wall | acid phosphatase activity phosphatase activity phosphatidylinositol-3-phosphate phosphatase activity phosphoenolpyruvate phosphatase activity phosphoglycerate phosphatase activity trehalose-phosphatase activity | Mycobacterium tuberculosis | Direct protein sequencing Host cytoplasmic vesicle Hydrolase Reference proteome Secreted Signal Virulence | MLRGIQALSR | MLRGIQALSRPLTRVYRALAVIGVLAASLLASWVGAVPQVGLAASALPTFAHVVIVVEENRSQAAIIGNKSAPFINSLAANGAMMAQAFAETHPSEPNYLALFAGNTFGLTKNTCPVNGGALPNLGSELLSAGYTFMGFAEDLPAVGSTVCSAGKYARKHVPWVNFSNVPTTLSVPFSAFPKPQNYPGLPTVSFVIPNADNDMHDGSIAQGDAWLNRHLSAYANWAKTNNSLLVVTWDEDDGSSRNQIPTVFYGAHVRPGTYNETISHYNVLSTLEQIYGLPKTGYATNAPPITDIWGD | NADP catabolic process phosphatidylinositol phosphate biosynthetic process suppression of host innate immune response cytoplasm; cytosol; extracellular region; host cell cytoplasmic vesicle; peptidoglycan-based cell wall acid phosphatase activity phosphatase activity phosphatidylinositol-3-phosphate phosphatase activit... |
glycolipid biosynthetic process lipoprotein biosynthetic process symbiont-mediated perturbation of host immune response | cytosol; peptidoglycan-based cell wall; plasma membrane | dolichyl-phosphate beta-D-mannosyltransferase activity hydrolase activity N-acyltransferase activity | Mycobacterium tuberculosis | Acyltransferase Cell membrane Glycosyltransferase Hydrolase Membrane Reference proteome Transferase Transmembrane Transmembrane helix | MKLGAWVAAQ | MKLGAWVAAQLPTTRTAVRTRLTRLVVSIVAGLLLYASFPPRNCWWAAVVALALLAWVLTHRATTPVGGLGYGLLFGLVFYVSLLPWIGELVGPGPWLALATTCALFPGIFGLFAVVVRLLPGWPIWFAVGWAAQEWLKSILPFGGFPWGSVAFGQAEGPLLPLVQLGGVALLSTGVALVGCGLTAIALEIEKWWRTGGQGDAPPAVVLPAACICLVLFAAIVVWPQVRHAGSGSGGEPTVTVAVVQGNVPRLGLDFNAQRRAVLDNHVEETLRLAADVHAGLAQQPQFVIWPENSSDIDPFVNPDAGQRISAAAEAIGA... | glycolipid biosynthetic process lipoprotein biosynthetic process symbiont-mediated perturbation of host immune response cytosol; peptidoglycan-based cell wall; plasma membrane dolichyl-phosphate beta-D-mannosyltransferase activity hydrolase activity N-acyltransferase activity Mycobacterium tuberculosis Acyltransferase ... |
amino acid biosynthetic process aromatic amino acid family biosynthetic process chorismate biosynthetic process protein homooligomerization | cytosol; peptidoglycan-based cell wall; plasma membrane | 3-deoxy-7-phosphoheptulonate synthase activity manganese ion binding | Mycobacterium tuberculosis | 3D-structure Amino-acid biosynthesis Aromatic amino acid biosynthesis Cadmium Cobalt Manganese Metal-binding Reference proteome Transferase | MNWTVDIPID | MNWTVDIPIDQLPSLPPLPTDLRTRLDAALAKPAAQQPTWPADQALAMRTVLESVPPVTVPSEIVRLQEQLAQVAKGEAFLLQGGDCAETFMDNTEPHIRGNVRALLQMAVVLTYGASMPVVKVARIAGQYAKPRSADIDALGLRSYRGDMINGFAPDAAAREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDWNREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQTAEIYASHEALVLDYERAMLRLSDGDDGEPQLFDLSAHTVWIGERTRQIDGAHIAFAQVIANPVGVKLGPNMTPELAVEYV... | amino acid biosynthetic process aromatic amino acid family biosynthetic process chorismate biosynthetic process protein homooligomerization cytosol; peptidoglycan-based cell wall; plasma membrane 3-deoxy-7-phosphoheptulonate synthase activity manganese ion binding Mycobacterium tuberculosis 3D-structure Amino-acid bios... |
Actinobacterium-type cell wall biogenesis lipid biosynthetic process long-chain fatty acid biosynthetic process | cytosol; plasma membrane | ATP binding butyrate-CoA ligase activity long-chain fatty acid transporter activity long-chain fatty acid-CoA ligase activity medium-chain fatty acid-CoA ligase activity | Mycobacterium tuberculosis | ATP-binding Fatty acid metabolism Ligase Lipid metabolism Nucleotide-binding Reference proteome | MTPTHPTVTE | MTPTHPTVTELLLPLSEIDDRGVYFEDSFTSWRDHIRHGAAIAAALRERLDPARPPHVGVLLQNTPFFSATLVAGALSGIVPVGLNPVRRGAALAGDIAKADCQLVLTGSGSAEVPADVEHINVDSPEWTDEVAAHRDTEVRFRSADLADLFMLIFTSGTSGDPKAVKCSHRKVAIAGVTITQRFSLGRDDVCYVSMPLFHSNAVLVGWAVAAACQGSMALRRKFSASQFLADVRRYGATYANYVGKPLSYVLATPELPDDADNPLRAVYGNEGVPGDIDRFGRRFGCVVMDGFGSTEGGVAITRTLDTPAGALGPLPGG... | Actinobacterium-type cell wall biogenesis lipid biosynthetic process long-chain fatty acid biosynthetic process cytosol; plasma membrane ATP binding butyrate-CoA ligase activity long-chain fatty acid transporter activity long-chain fatty acid-CoA ligase activity medium-chain fatty acid-CoA ligase activity Mycobacterium... |
Actinobacterium-type cell wall biogenesis fatty acid biosynthetic process lipid biosynthetic process mycolate cell wall layer assembly | peptidoglycan-based cell wall; plasma membrane | adenylyltransferase activity ATP binding ligase activity long-chain fatty acid ligase activity | Mycobacterium tuberculosis | 3D-structure ATP-binding Fatty acid metabolism Ligase Lipid metabolism Nucleotide-binding Phosphoprotein Reference proteome | MFVTGESGMA | MFVTGESGMAYHNPFIVNGKIRFPANTNLVRHVEKWAKVRGDKLAYRFLDFSTERDGVARDILWSDFSARNRAVGARLQQVTQPGDRVAILCPQNLDYLISFFGALYSGRIAVPLFDPAEPGHVGRLHAVLDDCAPSTILTTTDSAEGVRKFIRARSAKERPRVIAVDAVPTEVAATWQQPEANEETVAYLQYTSGSTRIPSGVQITHLNLPTNVVQVLNALEGQEGDRGVSWLPFFHDMGLITVLLASVLGHSFTFMTPAAFVRRPGRWIRELARKPGETGGTFSAAPNFAFEHAAVRGVPRDDEPPLDLSNVKGILNG... | Actinobacterium-type cell wall biogenesis fatty acid biosynthetic process lipid biosynthetic process mycolate cell wall layer assembly peptidoglycan-based cell wall; plasma membrane adenylyltransferase activity ATP binding ligase activity long-chain fatty acid ligase activity Mycobacterium tuberculosis 3D-structure AT... |
lipid catabolic process | extracellular region; peptidoglycan-based cell wall; plasma membrane | acyl-CoA hydrolase activity carboxylesterase activity lipase activity palmitoyl-CoA hydrolase activity phospholipase A1 activity | Mycobacterium tuberculosis | 3D-structure Cell membrane Cell wall Disulfide bond Hydrolase Membrane Reference proteome Secreted Serine esterase Transmembrane Transmembrane helix | MAKNSRRKRH | MAKNSRRKRHRILAWIAAGAMASVVALVIVAVVIMLRGAESPPSAVPPGVLPPGPTPAHPHKPRPAFQDASCPDVQMISVPGTWESSPQQNPLNPVQFPKALLLKVTGPIAQQFAPARVQTYTVAYTAQFHNPLTTDNQMSYNDSRAEGTRAMVAAMTDMNNRCPLTSYVLIGFSQGAVIAGDVASDIGNGRGPVDEDLVLGVTLIADGRRQQGVGNQVPPSPRGEGAEITLHEVPVLSGLGLTMTGPRPGGFGALDGRTNEICAQGDLICAAPAQAFSPANLPTTLNTLAGGAGQPVHAMYATPEFWNSDGEPATEWTL... | lipid catabolic process extracellular region; peptidoglycan-based cell wall; plasma membrane acyl-CoA hydrolase activity carboxylesterase activity lipase activity palmitoyl-CoA hydrolase activity phospholipase A1 activity Mycobacterium tuberculosis 3D-structure Cell membrane Cell wall Disulfide bond Hydrolase Membrane ... |
capsule polysaccharide biosynthetic process cell wall macromolecule biosynthetic process cell wall organization cell wall polysaccharide biosynthetic process lipopolysaccharide biosynthetic process mycolate cell wall layer assembly UDP-D-galactose metabolic process | cytosol; plasma membrane | glycosyltransferase activity lipopolysaccharide-1,5-galactosyltransferase activity lipopolysaccharide-1,6-galactosyltransferase activity metal ion binding transferase activity UDP-galactosyltransferase activity | Mycobacterium tuberculosis | 3D-structure Cell membrane Cell wall biogenesis/degradation Glycosyltransferase Magnesium Manganese Membrane Metal-binding Reference proteome Transferase | MSELAASLLS | MSELAASLLSRVILPRPGEPLDVRKLYLEESTTNARRAHAPTRTSLQIGAESEVSFATYFNAFPASYWRRWTTCKSVVLRVQVTGAGRVDVYRTKATGARIFVEGHDFTGTEDQPAAVETEVVLQPFEDGGWVWFDITTDTAVTLHSGGWYATSPAPGTANIAVGIPTFNRPADCVNALRELTADPLVDQVIGAVIVPDQGERKVRDHPDFPAAAARLGSRLSIHDQPNLGGSGGYSRVMYEALKNTDCQQILFMDDDIRLEPDSILRVLAMHRFAKAPMLVGGQMLNLQEPSHLHIMGEVVDRSIFMWTAAPHAEYDHD... | capsule polysaccharide biosynthetic process cell wall macromolecule biosynthetic process cell wall organization cell wall polysaccharide biosynthetic process lipopolysaccharide biosynthetic process mycolate cell wall layer assembly UDP-D-galactose metabolic process cytosol; plasma membrane glycosyltransferase activity ... |
cell wall organization peptidoglycan-protein cross-linking regulation of cell shape | extracellular region; periplasmic space | acyltransferase activity peptidoglycan L,D-transpeptidase activity | Mycobacterium tuberculosis | 3D-structure Acyltransferase Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis Periplasm Reference proteome Signal Transferase | MRRVVRYLSV | MRRVVRYLSVVVAITLMLTAESVSIATAAVPPLQPIPGVASVSPANGAVVGVAHPVVVTFTTPVTDRRAVERSIRISTPHNTTGHFEWVASNVVRWVPHRYWPPHTRVSVGVQELTEGFETGDALIGVASISAHTFTVSRNGEVLRTMPASLGKPSRPTPIGSFHAMSKERTVVMDSRTIGIPLNSSDGYLLTAHYAVRVTWSGVYVHSAPWSVNSQGYANVSHGCINLSPDNAAWYFDAVTVGDPIEVVG | cell wall organization peptidoglycan-protein cross-linking regulation of cell shape extracellular region; periplasmic space acyltransferase activity peptidoglycan L,D-transpeptidase activity Mycobacterium tuberculosis 3D-structure Acyltransferase Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis Perip... |
fatty acid biosynthetic process fatty acid metabolic process | fatty acid synthase complex; plasma membrane | (3R)-hydroxyacyl- dehydratase activity 3-hydroxyacyl-CoA dehydratase activity fatty acid synthase activity | Mycobacterium tuberculosis | 3D-structure Fatty acid metabolism Lipid metabolism Lyase Reference proteome | MTQPSGLKNL | MTQPSGLKNLLRAAAGALPVVPRTDQLPNRTVTVEELPIDPANVAAYAAVTGLRYGNQVPLTYPFALTFPSVMSLVTGFDFPFAAMGAIHTENHITQYRPIAVTDAVGVRVRAENLREHRRGLLVDLVTNVSVGNDVAWHQVTTFLHQQRTSLSGEPKPPPQKKPKLPPPAAVLRITPAKIRRYAAVGGDHNPIHTNPIAAKLFGFPTVIAHGMFTAAAVLANIEARFPDAVRYSVRFAKPVLLPATAGLYVAEGDGGWDLTLRNMAKGYPHLTATVRGL | fatty acid biosynthetic process fatty acid metabolic process fatty acid synthase complex; plasma membrane (3R)-hydroxyacyl- dehydratase activity 3-hydroxyacyl-CoA dehydratase activity fatty acid synthase activity Mycobacterium tuberculosis 3D-structure Fatty acid metabolism Lipid metabolism Lyase Reference proteome MTQ... |
fatty acid metabolic process response to host immune response | extracellular region; plasma membrane | butyryl-CoA dehydrogenase activity long-chain-acyl-CoA dehydrogenase activity medium-chain-acyl-CoA dehydrogenase activity | Mycobacterium tuberculosis | 3D-structure FAD Fatty acid metabolism Flavoprotein Lipid metabolism Oxidoreductase Reference proteome | MSHYRSNVRD | MSHYRSNVRDQVFNLFEVLGVDKALGHGEFSDVDVDTARDMLAEVSRLAEGPVAESFVEGDRNPPVFDPKTHSVMLPESFKKSVNAMLEAGWDKVGIDEALGGMPMPKAVVWALHEHILGANPAVWMYAGGAGFAQILYHLGTEEQKKWAVLAAERGWGSTMVLTEPDAGSDVGAARTKAVQQADGSWHIDGVKRFITSGDSGDLFENIFHLVLARPEGAGPGTKGLSLYFVPKFLFDVETGEPGERNGVFVTNVEHKMGLKVSATCELAFGQHGVPAKGWLVGEVHNGIAQMFEVIEQARMMVGTKAIATLSTGYLNAL... | fatty acid metabolic process response to host immune response extracellular region; plasma membrane butyryl-CoA dehydrogenase activity long-chain-acyl-CoA dehydrogenase activity medium-chain-acyl-CoA dehydrogenase activity Mycobacterium tuberculosis 3D-structure FAD Fatty acid metabolism Flavoprotein Lipid metabolism O... |
3'-phosphoadenosine 5'-phosphosulfate metabolic process sulfolipid biosynthetic process trehalose metabolic process | peptidoglycan-based cell wall; plasma membrane | 3'-phosphoadenosine 5'-phosphosulfate binding protein homodimerization activity sulfotransferase activity | Mycobacterium tuberculosis | Carbohydrate metabolism Reference proteome Transferase | MSRAVRPYLV | MSRAVRPYLVLATQRSGSTLLVESLRATGCAGEPQEFFQYLPSTGMAPQPREWFAGVDDDTILQLLDPLDPGTPDTATPVAWREHVRTSGRTPNGVWGGKLMWNQTALLQQRAAQLPDRSGDGLRAAIRDVIGNEPVFVHVHRPDVVSQAVSFWRAVQTQVWRGHPDPKRDSQAVYHAGAIAHIIRNLRDQENGWRAWFAEEGIDPIDIAYPVLWRNLTAIVASVLDAIGQDPKLAPAPMLERQANQRSDEWVDRYRAEAPRLGLPT | 3'-phosphoadenosine 5'-phosphosulfate metabolic process sulfolipid biosynthetic process trehalose metabolic process peptidoglycan-based cell wall; plasma membrane 3'-phosphoadenosine 5'-phosphosulfate binding protein homodimerization activity sulfotransferase activity Mycobacterium tuberculosis Carbohydrate metabolism ... |
cellular response to antibiotic protein catabolic process proteolysis | extracellular region; plasma membrane | serine-type endopeptidase activity serine-type peptidase activity | Mycobacterium tuberculosis | 3D-structure Cell inner membrane Cell membrane Cell wall Hydrolase Membrane Protease Reference proteome Secreted Serine protease Stress response Transmembrane Transmembrane helix | MAKLARVVGL | MAKLARVVGLVQEEQPSDMTNHPRYSPPPQQPGTPGYAQGQQQTYSQQFDWRYPPSPPPQPTQYRQPYEALGGTRPGLIPGVIPTMTPPPGMVRQRPRAGMLAIGAVTIAVVSAGIGGAAASLVGFNRAPAGPSGGPVAASAAPSIPAANMPPGSVEQVAAKVVPSVVMLETDLGRQSEEGSGIILSAEGLILTNNHVIAAAAKPPLGSPPPKTTVTFSDGRTAPFTVVGADPTSDIAVVRVQGVSGLTPISLGSSSDLRVGQPVLAIGSPLGLEGTVTTGIVSALNRPVSTTGEAGNQNTVLDAIQTDAAINPGNSGGA... | cellular response to antibiotic protein catabolic process proteolysis extracellular region; plasma membrane serine-type endopeptidase activity serine-type peptidase activity Mycobacterium tuberculosis 3D-structure Cell inner membrane Cell membrane Cell wall Hydrolase Membrane Protease Reference proteome Secreted Serine... |
amino acid transport defense response to Gram-negative bacterium defense response to Gram-positive bacterium killing of cells of another organism regulation of membrane potential | extracellular region | signaling receptor binding | Streptococcus mutans | Antibiotic Antimicrobial Bacteriocin Direct protein sequencing Lantibiotic Thioether bond | MNKLNSNAVV | MNKLNSNAVVSLNEVSDSELDTILGGNRWWQGVVPTVSYECRMNSWQHVFTCC | amino acid transport defense response to Gram-negative bacterium defense response to Gram-positive bacterium killing of cells of another organism regulation of membrane potential extracellular region signaling receptor binding Streptococcus mutansAntibiotic Antimicrobial Bacteriocin Direct protein sequencing Lantibioti... |
calcium-mediated signaling cell chemotaxis chemotaxis DN2 thymocyte differentiation DN3 thymocyte differentiation immune response isotype switching to IgA isotypes leukocyte migration involved in inflammatory response lymphocyte migration positive regulation of cytosolic calcium ion concentration positive regulation of... | cell surface; external side of plasma membrane; sperm flagellum; sperm midpiece; sperm plasma membrane; sperm principal piece | C-C chemokine binding C-C chemokine receptor activity | Mus musculus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MNSTESYFGT | MNSTESYFGTDDYDNTEYYSIPPDHGPCSLEEVRNFTKVFVPIAYSLICVFGLLGNIMVVMTFAFYKKARSMTDVYLLNMAITDILFVLTLPFWAVTHATNTWVFSDALCKLMKGTYAVNFNCGMLLLACISMDRYIAIVQATKSFRVRSRTLTHSKVICVAVWFISIIISSPTFIFNKKYELQDRDVCEPRYRSVSEPITWKLLGMGLELFFGFFTPLLFMVFCYLFIIKTLVQAQNSKRHRAIRVVIAVVLVFLACQIPHNMVLLVTAVNTGKVGRSCSTEKVLAYTRNVAEVLAFLHCCLNPVLYAFIGQKFRNYFM... | calcium-mediated signaling cell chemotaxis chemotaxis DN2 thymocyte differentiation DN3 thymocyte differentiation immune response isotype switching to IgA isotypes leukocyte migration involved in inflammatory response lymphocyte migration positive regulation of cytosolic calcium ion concentration positive regulation of... |
animal organ development canonical Wnt signaling pathway cell differentiation cell-matrix adhesion cytokine-mediated signaling pathway gene expression hair follicle development hair follicle placode formation immune response odontogenesis of dentin-containing tooth pigmentation positive regulation of canonical NF-kappa... | apical part of cell; collagen trimer; endoplasmic reticulum membrane; extracellular space; intracellular membrane-bounded organelle; lipid droplet; plasma membrane | death receptor agonist activity death receptor binding signaling receptor binding tumor necrosis factor receptor binding | Mus musculus | Alternative splicing Cell membrane Cleavage on pair of basic residues Collagen Developmental protein Differentiation Glycoprotein Membrane Reference proteome Secreted Signal-anchor Transmembrane Transmembrane helix | MGYPEVERRE | MGYPEVERREPLPAAAPRERGSQGCGCRGAPARAGEGNSCRLFLGFFGLSLALHLLTLCCYLELRSELRRERGTESRLGGPGAPGTSGTLSSPGSLDPVGPITRHLGQPSFQQQPLEPGEDPLPPDSQDRHQMALLNFFFPDEKAYSEEESRRVRRNKRSKSGEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKTGTRENQPAVVHLQGQGSAIQVKNDLSGGVLNDWSRITMNPKVFKLHPRSGELEVLVDGTYFIYSQVEVYYINFTDFASY... | animal organ development canonical Wnt signaling pathway cell differentiation cell-matrix adhesion cytokine-mediated signaling pathway gene expression hair follicle development hair follicle placode formation immune response odontogenesis of dentin-containing tooth pigmentation positive regulation of canonical NF-kappa... |
ceramide biosynthetic process positive regulation of lipophagy regulation of fat cell apoptotic process sphinganine biosynthetic process sphingomyelin biosynthetic process sphingosine biosynthetic process | endoplasmic reticulum membrane; serine C-palmitoyltransferase complex; SPOTS complex | pyridoxal phosphate binding serine C-palmitoyltransferase activity | Cricetulus griseus | Acyltransferase Endoplasmic reticulum Lipid metabolism Membrane Phosphoprotein Pyridoxal phosphate Sphingolipid metabolism Transferase Transmembrane Transmembrane helix | MAMAAEQWVL | MAMAAEQWVLVEMVQALYEAPAYHLILEGILILWIIRLVFSKTYKLQERSDLTAKEKEELIEEWQPEPLVPPVSKNHPALNYNIVSGPPTHNIVVNGKECVNFASFNFLGLLANPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEERLAKFMRTEEAIIYSYGFSTIASAIPAYSKRGDIVFVDSAACFAIQKGLQASRSDIKLFKHNDVADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTVCPLPELVKLKYKYKARIFLEESLSFGVLGEHGRGVTEHYGISIDDIDLISANMENALASVGGFCCG... | ceramide biosynthetic process positive regulation of lipophagy regulation of fat cell apoptotic process sphinganine biosynthetic process sphingomyelin biosynthetic process sphingosine biosynthetic process endoplasmic reticulum membrane; serine C-palmitoyltransferase complex; SPOTS complex pyridoxal phosphate binding se... |
peptide catabolic process proteolysis | apical plasma membrane; membrane | aminopeptidase activity calcium ion binding carboxypeptidase activity metallopeptidase activity protein homodimerization activity zinc ion binding | Rattus norvegicus | Aminopeptidase Calcium Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Membrane Metal-binding Metalloprotease Protease Reference proteome Signal-anchor Transmembrane Transmembrane helix Zinc | MHWAKILGVG | MHWAKILGVGIGAAALLGLGIILGHFAIPKATEPLASSVSDSQDLDLAILDSVMGQLDASRIRENLRELSKEPHVATSARDEALVQLLLGRWKDSASGLDTAKTYEYTVLLSFPSTEQPNSVEVVGPNGTVFHSFQPFEKNLTGEQAEPNVLQPYAAYAPPGTPKGPLVYANRGSEDDFKKLEAEGINLKGTIALTRYGSVGRGAKAINAARHGVVGVLVYTDPGDINDGKSLPNETFPNSWGLPPSGVERGSYYEYFGDPLTPYLPAHPVSFRLDPHNISGFPPIPTQPIGFEDAKNLLCNLNGTSAPDSWQGALGCEY... | peptide catabolic process proteolysis apical plasma membrane; membrane aminopeptidase activity calcium ion binding carboxypeptidase activity metallopeptidase activity protein homodimerization activity zinc ion binding Rattus norvegicus Aminopeptidase Calcium Cell membrane Direct protein sequencing Disulfide bond Glycop... |
adenine transport adenosine transport cellular response to glucose stimulus cellular response to hypoxia cytidine transport excitatory postsynaptic potential guanine transmembrane transport hypoxanthine transport inosine transport lactation neurotransmitter transport neurotransmitter uptake nucleobase transport nucleos... | apical plasma membrane; basolateral plasma membrane; plasma membrane; postsynapse; presynapse | adenine transmembrane transporter activity cytidine transmembrane transporter activity guanine transmembrane transporter activity neurotransmitter transmembrane transporter activity nucleoside transmembrane transporter activity purine nucleoside transmembrane transporter activity pyrimidine- and adenosine-specific:sodi... | Rattus norvegicus | Cell membrane Glycoprotein Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport | MTTSHQPQDR | MTTSHQPQDRYKAVWLIFFVLGLGTLLPWNFFITATQYFTSRLNTSQNISLVTNQSCESTEALADPSVSLPARSSLSAIFNNVMTLCAMLPLLIFTCLNSFLHQKVSQSLRILGSLLAILLVFLVTATLVKVQMDALSFFIITMIKIVLINSFGAILQASLFGLAGVLPANYTAPIMSGQGLAGFFTSVAMICAVASGSKLSESAFGYFITACAVVILAILCYLALPWMEFYRHYLQLNLAGPAEQETKLDLISEGEEPRGGREESGVPGPNSLPANRNQSIKAILKSIWVLALSVCFIFTVTIGLFPAVTAEVESSIAG... | adenine transport adenosine transport cellular response to glucose stimulus cellular response to hypoxia cytidine transport excitatory postsynaptic potential guanine transmembrane transport hypoxanthine transport inosine transport lactation neurotransmitter transport neurotransmitter uptake nucleobase transport nucleos... |
adenine transport adenosine transport cellular response to insulin stimulus cytidine transport guanine transmembrane transport guanine transport hypoxanthine transport inosine transport lactation neurotransmitter transport neurotransmitter uptake nucleobase transport nucleoside transmembrane transport nucleoside transp... | apical plasma membrane; basolateral plasma membrane; plasma membrane | adenine transmembrane transporter activity cytidine transmembrane transporter activity guanine transmembrane transporter activity neurotransmitter transmembrane transporter activity nucleobase transmembrane transporter activity nucleoside transmembrane transporter activity purine nucleoside transmembrane transporter ac... | Rattus norvegicus | Cell membrane Glycoprotein Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport | MAHGNAPRDS | MAHGNAPRDSYHLVGISFFILGLGTLLPWNFFITAIPYFQGRLAGTNSSAETPSTNHTSPTDTFNFNNWVTLLSQLPLLLFTLLNSFLYQCIPESVRILGSLLAILLLFALTAALVKVDLSPGLFFSITMASVWFINSFCAVLQGSLFGQLGTMPSTYSTLFLSGQGLAGIFAALAMLTSLASGVDPQTSALGYFITPCVGILLSIICYLSLPHLKFARYYLTKKPQAPVQELETKAELLGADEKNGIPVSPQQAGPTLDLDPEKELELGLEEPQKPGKPSVFVVFRKIWLTALCLVLVFTVTLSVFPAITAMVTTSSNS... | adenine transport adenosine transport cellular response to insulin stimulus cytidine transport guanine transmembrane transport guanine transport hypoxanthine transport inosine transport lactation neurotransmitter transport neurotransmitter uptake nucleobase transport nucleoside transmembrane transport nucleoside transp... |
calcium ion import calcium ion import across plasma membrane calcium ion transmembrane transport calcium ion transport establishment of localization in cell intracellular calcium ion homeostasis learning long-term synaptic depression long-term synaptic potentiation memory monoatomic ion transmembrane transport neuron c... | membrane; plasma membrane | calcium channel activity calcium, potassium:sodium antiporter activity symporter activity | Rattus norvegicus | Alternative splicing Antiport Calcium Calcium transport Cell membrane Glycoprotein Ion transport Membrane Phosphoprotein Potassium Potassium transport Reference proteome Repeat Sodium Sodium transport Symport Transmembrane Transmembrane helix Transport | MDLHQSATVR | MDLHQSATVRLLQEWCSHESPSGCRRHYNTRKKLKLIRVIGLVMGLVAVSTVPFSISAFTETYSQNNRGEASDVTGPRAAPGHRQRTLLDLNDKIRDYTPQPPASQEDRSENGTDHAQGDYPKDVFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREILNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFAYVVFMKFNVQVERWVKQMINRNKVVKVTVSEAQAKASTAGDKEE... | calcium ion import calcium ion import across plasma membrane calcium ion transmembrane transport calcium ion transport establishment of localization in cell intracellular calcium ion homeostasis learning long-term synaptic depression long-term synaptic potentiation memory monoatomic ion transmembrane transport neuron c... |
androgen metabolic process carbohydrate biosynthetic process estrogen metabolic process learning long-term memory proteoglycan biosynthetic process | Golgi membrane | HNK-1 sulfotransferase activity sulfotransferase activity | Rattus norvegicus | Carbohydrate metabolism Glycoprotein Golgi apparatus Lipid metabolism Membrane Reference proteome Signal-anchor Steroid metabolism Transferase Transmembrane Transmembrane helix | MHHQWLLLAA | MHHQWLLLAACFWVIFMFMVASKFITLTFKDPDGYSAKQEFVFLTAMPEAEKLRGEKHFSEVMKPTGKMLSESHPDQPPVYLERLELIRNACKEEALRNLSHTEVSKFVLDRIFVCDKHKILFCQTPKVGNTQWKKVLIVLNGAFSSIEEIPENVVHDHEKNGLPRLSSFSKIGIQKRLKTYFKFFIVRDPFERLISAFKDKFVHNPRFEPWYRHEIAPGIIRKYRKNRTETRGIQFEDFVRYLGDPNRRWLDLQFGDHIIHWVTYVKLCAPCEIKYSVIGHHETLEADAPYILKEAGIDHLVSYPTIPPGITMYNRTKV... | androgen metabolic process carbohydrate biosynthetic process estrogen metabolic process learning long-term memory proteoglycan biosynthetic process Golgi membrane HNK-1 sulfotransferase activity sulfotransferase activity Rattus norvegicus Carbohydrate metabolism Glycoprotein Golgi apparatus Lipid metabolism Membrane Re... |
adaptive immune response natural killer cell mediated immunity negative regulation of natural killer cell mediated cytotoxicity negative regulation of T cell mediated cytotoxicity positive regulation of natural killer cell mediated cytotoxicity regulation of natural killer cell activation stimulatory C-type lectin rece... | external side of plasma membrane; plasma membrane; receptor complex | carbohydrate binding HLA-E specific inhibitory MHC class Ib receptor activity MHC class I protein complex binding MHC class Ib protein binding, via antigen binding groove protein antigen binding transmembrane signaling receptor activity | Mus musculus | Adaptive immunity Cell membrane Disulfide bond Glycoprotein Immunity Innate immunity Lectin Membrane Receptor Reference proteome Signal-anchor Transmembrane Transmembrane helix | MAVSRITRWR | MAVSRITRWRLMSVIFGIKCLFLMVTLGVLLINSFTIQNIQSTPSPTTTVEFQEVSECCVCLDKWVGHQCNCYFISKEEKSWKRSRDFCASQNSSLLQPQSRNELSFMNFSQTFFWIGMHYSEKRNAWLWEDGTVPSKDLFPEFSVIRPEHCIVYSPSKSVSAESCENKNRYICKKLPI | adaptive immune response natural killer cell mediated immunity negative regulation of natural killer cell mediated cytotoxicity negative regulation of T cell mediated cytotoxicity positive regulation of natural killer cell mediated cytotoxicity regulation of natural killer cell activation stimulatory C-type lectin rece... |
adaptive immune response cell differentiation cellular response to lipopolysaccharide defense response to Gram-positive bacterium natural killer cell activation natural killer cell mediated cytotoxicity negative regulation of natural killer cell chemotaxis nitric oxide biosynthetic process positive regulation of apopto... | cell surface; external side of plasma membrane; plasma membrane | carbohydrate binding identical protein binding kinase binding MHC class I protein binding MHC class Ib receptor activity signaling receptor activity | Mus musculus | 3D-structure Adaptive immunity Alternative splicing Cell membrane Differentiation Disulfide bond Glycoprotein Immunity Innate immunity Lectin Membrane Receptor Reference proteome Signal-anchor Transmembrane Transmembrane helix | MALIRDRKSH | MALIRDRKSHHSEMSKCHNYDLKPAKWDTSQEQQKQRLALTTSQPGENGIIRGRYPIEKLKISPMFVVRVLAIALAIRFTLNTLMWLAIFKETFQPVLCNKEVPVSSREGYCGPCPNNWICHRNNCYQFFNEEKTWNQSQASCLSQNSSLLKIYSKEEQDFLKLVKSYHWMGLVQIPANGSWQWEDGSSLSYNQLTLVEIPKGSCAVYGSSFKAYTEDCANLNTYICMKRAV | adaptive immune response cell differentiation cellular response to lipopolysaccharide defense response to Gram-positive bacterium natural killer cell activation natural killer cell mediated cytotoxicity negative regulation of natural killer cell chemotaxis nitric oxide biosynthetic process positive regulation of apopto... |
negative regulation of DNA-templated transcription negative regulation of gene expression negative regulation of osteoclast differentiation negative regulation of protein sumoylation negative regulation of transcription by RNA polymerase II positive regulation of gene expression positive regulation of membrane potentia... | cytoplasm; dendrite; nuclear speck; nucleus | ionotropic glutamate receptor binding potassium channel regulator activity SUMO ligase activity SUMO transferase activity transcription coregulator activity transmembrane transporter binding zinc ion binding | Mus musculus | Alternative splicing Cytoplasm Isopeptide bond Metal-binding Nucleus Reference proteome Transcription Transcription regulation Transferase Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger | MAELGELKHM | MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKELYRRRFPRKTLGPSDLSLLSLPPGTSPVGSPGPLAPIPPTLLTPGTLLGPKREVDMHPPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFEEAHFTFALTPQQLQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTS... | negative regulation of DNA-templated transcription negative regulation of gene expression negative regulation of osteoclast differentiation negative regulation of protein sumoylation negative regulation of transcription by RNA polymerase II positive regulation of gene expression positive regulation of membrane potentia... |
cellular response to increased oxygen levels endosome to plasma membrane protein transport intracellular iron ion homeostasis osteoclast development regulation of cellular pH synaptic vesicle lumen acidification | clathrin-coated vesicle membrane; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; endosome membrane; membrane; proton-transporting V-type ATPase complex; synaptic vesicle membrane | ATPase activator activity small GTPase binding transporter activator activity | Rattus norvegicus | 3D-structure Cytoplasmic vesicle Endoplasmic reticulum Glycoprotein Hydrogen ion transport Ion transport Membrane Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MMAATVVSRI | MMAATVVSRIRTGTRWAPVLWLLLSLVAVAAAVAAEQQVPLVLWSSDRDLWAPVADTHEGHITSDMQLSTYLDPALELGPRNVLLFLQDKLSIEDFTAYGGVFGNKQDSAFSNLENALDLAPSSLVLPAVDWYAISTLTTYLQEKLGASPLHVDLATLKELKLNASLPALLLIRLPYTASSGLMAPREVLTGNDEVIGQVLSTLESEDVPYTAALTAVRPSRVARDVAMVAGGLGRQLLQTQVASPAIHPPVSYNDTAPRILFWAQNFSVAYKDEWKDLTSLTFGVENLNLTGSFWNDSFAMLSLTYEPLFGATVTFKFI... | cellular response to increased oxygen levels endosome to plasma membrane protein transport intracellular iron ion homeostasis osteoclast development regulation of cellular pH synaptic vesicle lumen acidification clathrin-coated vesicle membrane; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate c... |
positive regulation of cell motility protein secretion rRNA transcription termination of RNA polymerase I transcription transcription initiation at RNA polymerase I promoter | caveola; cytoplasm; cytosol; endoplasmic reticulum; intracellular membrane-bounded organelle; membrane raft; mitochondrion; nucleus; plasma membrane; protein-containing complex | identical protein binding rRNA primary transcript binding | Mus musculus | 3D-structure Acetylation Cell membrane Coiled coil Cytoplasm Endoplasmic reticulum Isopeptide bond Membrane Microsome Mitochondrion Nucleus Phosphoprotein Reference proteome Repeat RNA-binding rRNA-binding Transcription Transcription regulation Transcription termination Ubl conjugation | MEDVTLHIVE | MEDVTLHIVERPYSGFPDASSEGPEPTQGEARATEEPSGTGSDELIKSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSVSKSLKESEALPEKEGDELGEGERPEDDTAAIELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPVERREKLKTSRDKLRKSFTPDHVVYARSKTAVYKV... | positive regulation of cell motility protein secretion rRNA transcription termination of RNA polymerase I transcription transcription initiation at RNA polymerase I promoter caveola; cytoplasm; cytosol; endoplasmic reticulum; intracellular membrane-bounded organelle; membrane raft; mitochondrion; nucleus; plasma membra... |
collagen catabolic process endodermal cell differentiation extracellular matrix organization proteolysis response to estradiol | extracellular matrix; extracellular space; membrane | metalloendopeptidase activity zinc ion binding | Mus musculus | Calcium Cleavage on pair of basic residues Disulfide bond Glycoprotein Hydrolase Membrane Metal-binding Metalloprotease Protease Reference proteome Repeat Signal Transmembrane Transmembrane helix Zinc Zymogen | MGSDRSALGR | MGSDRSALGRPGCTGSCLSSRASLLPLLLVLLDCLGHGTASKDAEVYAAENWLRLYGYLPQPSRHMSTMRSAQILASALAEMQSFYGIPVTGVLDEETKTWMKRPRCGVPDQFGVHVKANLRRRRKRYTLTGKAWNNYHLTFSIQNYTEKLGWYNSMEAVRRAFQVWEQVTPLVFQEVSYDDIRLRRRAEADIMVLFASGFHGDSSPFDGVGGFLAHAYFPGPGLGGDTHFDADEPWTFSSTDLHGISLFLVAVHELGHALGLEHSSNPSAIMAPFYQWMDTDNFQLPEDDLRGIQQLYGSPDGKPQPTRPLPTVRPRRP... | collagen catabolic process endodermal cell differentiation extracellular matrix organization proteolysis response to estradiol extracellular matrix; extracellular space; membrane metalloendopeptidase activity zinc ion binding Mus musculus Calcium Cleavage on pair of basic residues Disulfide bond Glycoprotein Hydrolase ... |
animal organ morphogenesis embryonic camera-type eye morphogenesis embryonic digestive tract development establishment of planar polarity of embryonic epithelium extracellular matrix organization genitalia development negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription ... | intracellular membrane-bounded organelle; nuclear body; nucleoplasm; nucleus; transcription regulator complex | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific general transcription initiation factor binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA p... | Mus musculus | Activator DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MSTEGGPPPP | MSTEGGPPPPPPRPPPAPLRRACSPAPGALQAALMSPPPAATLESTSSSSSSSSASCASSSSNSVSASAGACKSAASSGGAGAGSGGTKKATSGLRRPEKPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYHRVVSGLGFGASLLPQGFDFQAPPSAPLGCHGQGGYGGLDMMPAGYDTGAGAPGHAHPHHLHHHHVPHMSPNPGSTYMASCPVPAGPAGVGAAAGGGGGGGDYGPDSSSSPVP... | animal organ morphogenesis embryonic camera-type eye morphogenesis embryonic digestive tract development establishment of planar polarity of embryonic epithelium extracellular matrix organization genitalia development negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription ... |
angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure epoxygenase P450 pathway icosanoid metabolic process linoleic acid metabolic process organic acid metabolic process positive regulation of estrogen secretion regulation of systemic arterial blood pressure by hormone renal t... | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle | arachidonic acid 11,12-epoxygenase activity arachidonic acid 14,15-epoxygenase activity arachidonic acid epoxygenase activity aromatase activity heme binding iron ion binding isomerase activity linoleic acid epoxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecu... | Mus musculus | Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome | MIMFLSSLVT | MIMFLSSLVTTFWEALHLKTLVLAVVTFLFLINILRSRHPKNYPPGPWRLPFVGNFFQIDTKQTHLVLQQFVKKYGNVFSLELGQSPVVVVSGLPLIKEMFTHLDQNFVNRFMTPVRERITGKNGLVVSNGQTWKEQRRLALMALRNFGLGKKSLEERIQEETHHLVEAIREEGGQPFNPHLKLINAVSNIICSVTFGERFDYEDCQFQELLQLLDETMHLMGSSAGQLYNGFPCIMKYLPGPHQKIFRNWGKLKLFVSHIVKKHEKDWNPDEPRDFIDAFLIEMQKDPDRTTSFNEENLISTTLDLFLGGTETTSSTLR... | angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure epoxygenase P450 pathway icosanoid metabolic process linoleic acid metabolic process organic acid metabolic process positive regulation of estrogen secretion regulation of systemic arterial blood pressure by hormone renal t... |
arachidonic acid metabolic process epoxygenase P450 pathway icosanoid metabolic process linoleic acid metabolic process negative regulation of collagen biosynthetic process negative regulation of peroxisome proliferator activated receptor signaling pathway organic acid metabolic process positive regulation of extracell... | cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; intracellular membrane-bounded organelle | arachidonic acid 11,12-epoxygenase activity arachidonic acid 14,15-epoxygenase activity arachidonic acid epoxygenase activity arachidonic acid monooxygenase activity aromatase activity heme binding iron ion binding isomerase activity linoleic acid epoxygenase activity NADPH-hemoprotein reductase activity oxidoreductase... | Mus musculus | Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome | MLAATGSLLA | MLAATGSLLATIWAALHPRTLLVAAVTFLLLADYFKNRRPKNYPPGPWGLPFVGNIFQLDFGQPHLSIQPLVKKYGNIFSLNLGDITSVVITGLPLIKEALTQMEQNIMNRPLSVMQERISNKNGLIFSSGQIWKEQRRFALMTLRNFGLGKKSLEERMQEEASHLVEAIREEEGKPFNPHFSINNAVSNIICSVTFGERFDYHDSRFQEMLRLLDEVMYLETTMISQLYNIFPWIMKYIPGSHQKVFRNWEKLKLFVSCMIDDHRKDWNPDEPRDFIDAFLKEMTKYPEKTTSFNEENLICSTLDLFFAGTETTSTTLR... | arachidonic acid metabolic process epoxygenase P450 pathway icosanoid metabolic process linoleic acid metabolic process negative regulation of collagen biosynthetic process negative regulation of peroxisome proliferator activated receptor signaling pathway organic acid metabolic process positive regulation of extracell... |
cell differentiation nervous system development positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II response to stimulus retina development in camera-type eye visual perception | chromatin; nucleus; RNA polymerase II transcription regulator complex; transcription regulator complex | chromatin binding DNA binding DNA-binding transcription activator activity DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific leucine zipper domain binding nuclear receptor binding RNA p... | Mus musculus | Activator Developmental protein Differentiation DNA-binding Homeobox Neurogenesis Nucleus Reference proteome Sensory transduction Transcription Transcription regulation Vision | MMAYMNPGPH | MMAYMNPGPHYSVNALALSGPNVDLMHQAVPYSSAPRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGAQTKARPAKRKAGTSPRPSTDVCTDPLGISDSYSPSLPGPSGSPTTAVATVSIWSPASEAPLPEAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYASPSSYFSGLDPYLSPMVPQLGGPALSPLSGPSVGPSLAQSPTSLSGQSYSTYSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL | cell differentiation nervous system development positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II response to stimulus retina development in camera-type eye visual perception chromatin; nucleus; RNA polymerase II transcri... |
androgen metabolic process brexanolone catabolic process retinol metabolic process steroid metabolic process | endoplasmic reticulum membrane; intracellular membrane-bounded organelle | 5alpha-androstane-3beta,17beta-diol dehydrogenase activity androstan-3-alpha,17-beta-diol dehydrogenase activity androsterone dehydrogenase activity estradiol 17-beta-dehydrogenase activity NAD-retinol dehydrogenase activity testosterone 17-beta-dehydrogenase (NADP+) activity testosterone dehydrogenase (NAD+) activity... | Rattus norvegicus | Endoplasmic reticulum Glycoprotein Lipid metabolism Membrane Microsome NAD Oxidoreductase Reference proteome Signal Steroid metabolism | MWFYLVTLVG | MWFYLVTLVGLYYLLRWYRERQVVSHLHDKYVFITGCDSGFGNLLARQLDRRGMRVLAACLTEKGAEELKSKTSDRLETVILDVTNTDSISAATQWVKEHVGDKGLWGLVNNAGVFQAFAYIEWCRPEDCMSIFQVNLIGLAQVTLSMLFLVKKARGRIVNVSSVLGRVALFGGFYSCSKYGVEAFSDVLRREIRDFGVKVSIIEPGSFKTRMTDAELIIEKTKKTWEATPEHIRESYGQQFFDDFCNTTRRELKKCSTNLSLVTDCMEHALTSKYPRTRYSAGWDARLFFIPLSYLPTSLVDCLLAISRRKPAQAV | androgen metabolic process brexanolone catabolic process retinol metabolic process steroid metabolic process endoplasmic reticulum membrane; intracellular membrane-bounded organelle 5alpha-androstane-3beta,17beta-diol dehydrogenase activity androstan-3-alpha,17-beta-diol dehydrogenase activity androsterone dehydrogenas... |
binding of sperm to zona pellucida prevention of polyspermy | collagen-containing extracellular matrix; egg coat; extracellular region; plasma membrane | acrosin binding structural constituent of egg coat | Rattus norvegicus | Cell membrane Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Extracellular matrix Fertilization Glycoprotein Membrane Pyrrolidone carboxylic acid Reference proteome Secreted Signal Transmembrane Transmembrane helix | MAWGCFVVLL | MAWGCFVVLLLLVAAPLRLGQHLHLKPGFQYSYDCGVQGMQLLVFPRPNQTIQFKVLDEFGNRFEVNNCSICYHWVISEAQKPAVFSADYKGCHVLEKQDGRFHLRVFIQAVLPNGRVDTAQDVTLICPKPDHILTPESYLAPPTTPQPFIPHTFALHPISGHTLAGSGHTGLTTLYPETHPTPAPPSSEPGPVGPTVPQSQWGTLGSWELTELDSIGTHLLQERCQVASGHIPCMVKGSSEEACQQAGCCYDNTKEMPCYYGNTVTLQCFRSGYFTLVMSQETALTHGVMLDNVHLAYAPNGCPPTQKTSAFVVFHVPL... | binding of sperm to zona pellucida prevention of polyspermy collagen-containing extracellular matrix; egg coat; extracellular region; plasma membrane acrosin binding structural constituent of egg coat Rattus norvegicus Cell membrane Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Extracellul... |
binding of sperm to zona pellucida prevention of polyspermy | collagen-containing extracellular matrix; egg coat; endoplasmic reticulum; extracellular region; multivesicular body; plasma membrane | acrosin binding identical protein binding structural constituent of egg coat | Rattus norvegicus | Cell membrane Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Extracellular matrix Fertilization Glycoprotein Membrane Receptor Reference proteome Secreted Signal Transmembrane Transmembrane helix | MARWQRVYWL | MARWQRVYWLRSLFFALVTSVNSLSLPQSENPAFPGTLICDKDEVRVEFSSRFDMEKWNPSLVDTFGNEISNCTYALDLEKFILKFPYETCTIKVIGGYQVNIRVQDTNADVSYKDDVHHFFCPAIQAEIHEVSEIVVCMEDLISFSFPQLFSRLADENQNVSEMGWIIKIGNGTRVHTLPLKDAIVQGFNLLIDSQKITLHVPANATGVAHYVQESSYLYTVQLKLLFSSPGQKITFSSQAICAPDLSVACNVTHMSLTIPEFPGKLKSVGFGQRNIPEDQWHANGIDKEATNGLRLHFRKSLLKTKPSEKCPFYQFYF... | binding of sperm to zona pellucida prevention of polyspermy collagen-containing extracellular matrix; egg coat; endoplasmic reticulum; extracellular region; multivesicular body; plasma membrane acrosin binding identical protein binding structural constituent of egg coat Rattus norvegicus Cell membrane Cleavage on pair ... |
bone development cell adhesion glucose homeostasis negative regulation of chondrocyte differentiation negative regulation of fat cell differentiation osteoblast differentiation osteoclast differentiation positive regulation of cell growth involved in cardiac muscle cell development positive regulation of inflammatory r... | cytoplasm; cytosol; extracellular matrix; extracellular space | heparin binding integrin binding | Mus musculus | Cell adhesion Disulfide bond Glycoprotein Proto-oncogene Reference proteome Secreted Signal Wnt signaling pathway | MRWLLPWTLA | MRWLLPWTLAAVAVLRVGNILATALSPTPTTMTFTPAPLEETTTRPEFCKWPCECPQSPPRCPLGVSLITDGCECCKICAQQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVCAQVVGVGCVLDGVRYTNGESFQPNCRYNCTCIDGTVGCTPLCLSPRPPRLWCRQPRHVRVPGQCCEQWVCDDDARRPRQTALLDTRAFAASGAVEQRYENCIAYTSPWSPCSTTCGLGISTRISNVNARCWPEQESRLCNLRPCDVDIQLHIKAGKKCLAVYQPEEATNFTLAGCVSTRTYRPKYCGVCTDNRCCIPYKSKTISV... | bone development cell adhesion glucose homeostasis negative regulation of chondrocyte differentiation negative regulation of fat cell differentiation osteoblast differentiation osteoclast differentiation positive regulation of cell growth involved in cardiac muscle cell development positive regulation of inflammatory r... |
angiogenesis cell differentiation intracellular signal transduction negative regulation of viral genome replication nuclear speck organization positive regulation of cell cycle positive regulation of cell population proliferation positive regulation of gene expression positive regulation of neuron apoptotic process pos... | chromatin; cytoplasm; cytosol; nuclear speck; nucleolus; nucleoplasm; nucleus | 14-3-3 protein binding ATP binding magnesium ion binding protein serine kinase activity protein serine/threonine kinase activity | Mus musculus | ATP-binding Chromosome Cytoplasm Differentiation Kinase mRNA processing mRNA splicing Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MSVNSEKSSS | MSVNSEKSSSSERPEPQQKAPLVPPPPPPPPPPPLPDPAPPEPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNYQGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYVRRMAAEATEWQKAGAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAERKILEENITSAEASGEQDGEYQPE... | angiogenesis cell differentiation intracellular signal transduction negative regulation of viral genome replication nuclear speck organization positive regulation of cell cycle positive regulation of cell population proliferation positive regulation of gene expression positive regulation of neuron apoptotic process pos... |
apoptotic process apoptotic signaling pathway cellular response to type II interferon chromatin organization intracellular signal transduction negative regulation of translation positive regulation of apoptotic process positive regulation of canonical Wnt signaling pathway positive regulation of cell migration positive... | actin filament; centrosome; chromosome, centromeric region; cytoplasm; cytosol; membrane raft; nucleoplasm; nucleus; PML body | ATP binding DNA-binding transcription factor binding identical protein binding kinase activity leucine zipper domain binding protein homodimerization activity protein serine kinase activity protein serine/threonine kinase activity small GTPase binding | Mus musculus | Activator Apoptosis ATP-binding Centromere Chromatin regulator Chromosome Cytoplasm Cytoskeleton Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transcription Transcription regulation Transferase Ubl conjugation | MSTFRQEDVE | MSTFRQEDVEDHYEMGEELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREIRHPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKHAASPRIKLIDFGIAHRIEAGSEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSSTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKVRRREDGARKPERRRLRAARLREYSLKSHSSMPRNTSYASFERF... | apoptotic process apoptotic signaling pathway cellular response to type II interferon chromatin organization intracellular signal transduction negative regulation of translation positive regulation of apoptotic process positive regulation of canonical Wnt signaling pathway positive regulation of cell migration positive... |
actin cytoskeleton organization astral microtubule organization cornea development in camera-type eye establishment of vesicle localization head development negative regulation of cilium assembly positive regulation of protein localization to nucleus positive regulation of protein phosphorylation protein phosphorylatio... | centrosome; cis-Golgi network; cytoplasm; mitotic spindle; nucleus; perinuclear region of cytoplasm | ATP binding metal ion binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Mus musculus | 3D-structure Alternative splicing ATP-binding Cytoplasm Cytoskeleton Kinase LIM domain Metal-binding Nucleotide-binding Nucleus Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transferase Zinc | MAALAGDEAW | MAALAGDEAWRCRGCGTYVPLSQRLYRTANEAWHGSCFRCSECQESLTNWYYEKDGKLYCHKDYWAKFGEFCHGCSLLMTGPAMVAGEFKYHPECFACMSCKVIIEDGDAYALVQHATLYCGKCHNEVVLAPMFERLSTESVQDQLPYSVTLISMPATTECRRGFSVTVESASSNYATTVQVKEVNRMHISPNNRNAIHPGDRILEINGTPVRTLRVEEVEDAIKQTSQTLQLLIEHDPVPQRLDQLRLDARLPPHMQSTGHTLMLSTLDTKENQEGTLRRRSLRRSNSISKSPGPSSPKEPLLLSRDISRSESLRCSSS... | actin cytoskeleton organization astral microtubule organization cornea development in camera-type eye establishment of vesicle localization head development negative regulation of cilium assembly positive regulation of protein localization to nucleus positive regulation of protein phosphorylation protein phosphorylatio... |
apoptotic DNA fragmentation chaperone-mediated protein folding negative regulation of apoptotic DNA fragmentation negative regulation of execution phase of apoptosis positive regulation of apoptotic process thymocyte apoptotic process | chromatin; cytosol; nucleus; plasma membrane; protein-containing complex | deoxyribonuclease inhibitor activity protein domain specific binding protein folding chaperone | Mus musculus | 3D-structure Acetylation Alternative splicing Apoptosis Cytoplasm Phosphoprotein Reference proteome | MELSRGASAP | MELSRGASAPDPDDVRPLKPCLLRRNHSRDQHGVAASSLEELRSKACELLAIDKSLTPITLVLAEDGTIVDDDDYFLCLPSNTKFVALACNEKWIYNDSDGGTAWVSQESFEADEPDSRAGVKWKNVARQLKEDLSSIILLSEEDLQALIDIPCAELAQELCQSCATVQGLQSTLQQVLDQREEARQSKQLLELYLQALEKEGNILSNQKESKAALSEELDAVDTGVGREMASEVLLRSQILTTLKEKPAPELSLSSQDLESVSKEDPKALAVALSWDIRKAETVQQACTTELALRLQQVQSLHSLRNLSARRSPLPGEP... | apoptotic DNA fragmentation chaperone-mediated protein folding negative regulation of apoptotic DNA fragmentation negative regulation of execution phase of apoptosis positive regulation of apoptotic process thymocyte apoptotic process chromatin; cytosol; nucleus; plasma membrane; protein-containing complex deoxyribonuc... |
apoptotic chromosome condensation apoptotic DNA fragmentation DNA catabolic process negative regulation of apoptotic DNA fragmentation | chromatin; cytosol; nucleolus; nucleoplasm; nucleus; protein-containing complex | disordered domain specific binding DNA binding DNA endonuclease activity DNA nuclease activity enzyme binding identical protein binding nuclease activity protein domain specific binding | Mus musculus | 3D-structure Apoptosis Cytoplasm Hydrolase Nuclease Nucleus Reference proteome | MCAVLRQPKC | MCAVLRQPKCVKLRALHSACKFGVAARSCQELLRKGCVRFQLPMPGSRLCLYEDGTEVTDDCFPGLPNDAELLLLTAGETWHGYVSDITRFLSVFNEPHAGVIQAARQLLSDEQAPLRQKLLADLLHHVSQNITAETREQDPSWFEGLESRFRNKSGYLRYSCESRIRGYLREVSAYTSMVDEAAQEEYLRVLGSMCQKLKSVQYNGSYFDRGAEASSRLCTPEGWFSCQGPFDLESCLSKHSINPYGNRESRILFSTWNLDHIIEKKRTVVPTLAEAIQDGREVNWEYFYSLLFTAENLKLVHIACHKKTTHKLECDRS... | apoptotic chromosome condensation apoptotic DNA fragmentation DNA catabolic process negative regulation of apoptotic DNA fragmentation chromatin; cytosol; nucleolus; nucleoplasm; nucleus; protein-containing complex disordered domain specific binding DNA binding DNA endonuclease activity DNA nuclease activity enzyme bin... |
adult behavior in utero embryonic development positive regulation of gene expression positive regulation of transcription by RNA polymerase II regulation of cell population proliferation regulation of cellular pH regulation of epidermal cell differentiation regulation of transcription by RNA polymerase II | nucleus; RNA polymerase II transcription regulator complex; transcription regulator complex | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific identical protein binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | 3D-structure Acetylation DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Ubl conjugation | MTTPNKGNKA | MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIIQLKQRRRTLKNRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQNFARTVARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS | adult behavior in utero embryonic development positive regulation of gene expression positive regulation of transcription by RNA polymerase II regulation of cell population proliferation regulation of cellular pH regulation of epidermal cell differentiation regulation of transcription by RNA polymerase II nucleus; RNA ... |
glycerol transmembrane transport renal water absorption urea transport water transport | basolateral plasma membrane; brush border membrane; cell cortex; cell-cell junction; cytoplasm; cytoplasmic vesicle membrane; lipid droplet; plasma membrane; ribonucleoprotein complex | glycerol channel activity urea channel activity urea transmembrane transporter activity water channel activity | Mus musculus | Cell membrane Cytoplasm Cytoplasmic vesicle Lipid droplet Membrane Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix Transport | MAPRSVLETI | MAPRSVLETIQSVLQKNMVREFLAEFLSTYVMMVFGLGSVAHMVLGENSGSYLGVNLGFGFGVTMGVHVAGGISGAHMNAAVTFTNCALGRMTWKKFPVYVLGQFLGSFSAAATTYLIFYGAINHFAGGDLLVTGSKATANIFATYLPEYMTLWRGFLDEAFVTGMLQLCLFAITDKKNSPALQGTEPLVIGILVTVLGVSLGMNSGYAINPSRDLPPRLFTFIAGWGKQVFRAGNNWWWVPVVAPLLGAYLGGIVYLGLIHPSIPQDPQRLENFTARDQKVTASYKNAASANISGSVPLEHF | glycerol transmembrane transport renal water absorption urea transport water transport basolateral plasma membrane; brush border membrane; cell cortex; cell-cell junction; cytoplasm; cytoplasmic vesicle membrane; lipid droplet; plasma membrane; ribonucleoprotein complex glycerol channel activity urea channel activity u... |
antiviral innate immune response G protein-coupled receptor signaling pathway negative regulation of interleukin-6 production positive regulation of interferon-alpha production positive regulation of osteoclast proliferation positive regulation of respiratory gaseous exchange sneeze reflex | cytosol; plasma membrane | bombesin receptor activity neuropeptide receptor activity | Mus musculus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MPPRSLSNLS | MPPRSLSNLSFPTEANESELVPEVWEKDFLPDSDGTTAELVIRCVIPSLYLIIISVGLLGNIMLVKIFLTNSAMRNVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWVFGKLGCKLIPAIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGVLLWTSLKAVGIWVVSVLLAVPEAVFSEVARIGSLDNSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLVIISIYYYHIAKTLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFVFCWFPNHVLYLYRSFNYKEIDPSLGHMIVTLVARVLSFSNSCVN... | antiviral innate immune response G protein-coupled receptor signaling pathway negative regulation of interleukin-6 production positive regulation of interferon-alpha production positive regulation of osteoclast proliferation positive regulation of respiratory gaseous exchange sneeze reflex cytosol; plasma membrane bomb... |
adherens junction organization calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules cell morphogenesis cell-cell adhesion cell-cell adhesion mediated by cadherin cell-cell junction assembly chemical synaptic transmission homophilic cell adhesion via plasma membrane adhesion molecules regulat... | adherens junction; axon terminus; catenin complex; glutamatergic synapse; synaptic cleft; synaptic membrane | cadherin binding calcium ion binding identical protein binding | Rattus norvegicus | Alternative splicing Calcium Cell adhesion Cell membrane Cleavage on pair of basic residues Glycoprotein Membrane Metal-binding Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix | MPERLAETLL | MPERLAETLLDLWTPLIILWITLPSFVYMAPMNQAHVLTTGSPLELSRQSEEMRILNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSGDGAGTIFQINDITGDIHAIKRLDREEKAEYTLTAQAVDWETNKPLEPPSEFIIKVQDINDNAPEFLNGPYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQPYFSIEPETAIIKTALPNMDREAKEEYLVVIQAKDMGGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDVVLGTAIGRVKANDQDIGENAQSSYDIIDGDG... | adherens junction organization calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules cell morphogenesis cell-cell adhesion cell-cell adhesion mediated by cadherin cell-cell junction assembly chemical synaptic transmission homophilic cell adhesion via plasma membrane adhesion molecules regulat... |
calcium ion transmembrane transport response to ATP | cell junction; cytoplasm; dendritic spine; glutamatergic synapse; neuronal cell body; parallel fiber to Purkinje cell synapse; plasma membrane; postsynaptic specialization membrane; receptor complex | ATP binding extracellularly ATP-gated monoatomic cation channel activity protein-containing complex binding purinergic nucleotide receptor activity | Mus musculus | Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Receptor Reference proteome Transmembrane Transmembrane helix Transport | MQLQPAGTGN | MQLQPAGTGNMASAAAAALVSWGFLDYKTEKYVLTRNCRVGVSQRLLQLAVVVYVIGWALLAKKGYQERDLAPQTSVITKLKGVSVTQVKELENRLWDVADFVKPSQGENVFFLVTNFLVTPAQVQGRCPEHPSVPLANCWADEDCPEGETGTYSHGIKTGQCVVFNGTHRTCEIWSWCPVESGAVPRKPLLAQAKNFTLFIKNTVTFSKFNFSRSNALLTWDNTYFKHCLYDPLSSPYCPVFRIGDLVAMAGGDFEDLALLGGAVGISIHWDCNLDTKGSDCCPQYSFQLQQKGYNFRTANHWWAASGVETRSLLKLYG... | calcium ion transmembrane transport response to ATP cell junction; cytoplasm; dendritic spine; glutamatergic synapse; neuronal cell body; parallel fiber to Purkinje cell synapse; plasma membrane; postsynaptic specialization membrane; receptor complex ATP binding extracellularly ATP-gated monoatomic cation channel activ... |
CDP-choline pathway cellular response to glucose starvation choline metabolic process ethanolamine metabolic process lipid droplet disassembly phosphatidylcholine biosynthetic process phosphatidylethanolamine biosynthetic process phosphorylation | cytoplasm; cytosol; lipid droplet | ATP binding choline binding choline kinase activity cholinesterase activity ethanolamine kinase activity identical protein binding protein homodimerization activity protein tyrosine kinase activity | Mus musculus | Acetylation Alternative splicing ATP-binding Cytoplasm Kinase Lipid biosynthesis Lipid droplet Lipid metabolism Nucleotide-binding Phospholipid biosynthesis Phospholipid metabolism Phosphoprotein Reference proteome Transferase | MKTKFCTGGE | MKTKFCTGGEAEPSPLGLLLSCGGNAAPTPGVGQQRDAAGELESKQLGGRTQPLALPPPPPPPLPLPPPPSPPLADEQPEPRTRRRAYLWCKEFLPGAWRGLREDQFHISVIRGGLSNMLFQCSLPDSIASVGDEPRKVLLRLYGAILKMRSCNKEGSEQAQNENEFQGAEAMVLESVMFAILAERSLGPKLFGIFPQGRLEQFIPSRRLDTEELRLPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLNQVLRLKFSREARVQQLHKILSYNLPLELENLRSLLQYTRSPVVFCHNDCQEGNILLLEGQENSERR... | CDP-choline pathway cellular response to glucose starvation choline metabolic process ethanolamine metabolic process lipid droplet disassembly phosphatidylcholine biosynthetic process phosphatidylethanolamine biosynthetic process phosphorylation cytoplasm; cytosol; lipid droplet ATP binding choline binding choline kina... |
angioblast cell migration calcium-mediated signaling cell chemotaxis chemotaxis eosinophil chemotaxis ERK1 and ERK2 cascade immune response inflammatory response mast cell chemotaxis positive regulation of angiogenesis positive regulation of cytosolic calcium ion concentration positive regulation of endothelial cell pr... | cytoplasm; endosome; external side of plasma membrane; extracellular space | C-C chemokine binding C-C chemokine receptor activity chemokine receptor activity | Rattus norvegicus | Cell membrane G-protein coupled receptor Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MASNEEELKT | MASNEEELKTVVETFETTPYEYEWAPPCEKVSIRELGSWLLPPLYSLVFIVGLLGNMMVVLILIKYRKLQIMTNIYLLNLAISDLLFLFTVPFWIHYVLWNEWGFGHCMCKMLSGLYYLALYSEIFFIILLTIDRYLAIVHAVLALRARTVTFATITSIITWGFAVLAALPEFIFHESQDNFGDLSCSPRYPEGEEDSWKRFHALRMNIFGLALPLLIMVICYSGIIKTLLRCPNKKKHKAIQLIFVVMIVFFIFWTPYNLVLLLSAFHSTFLETSCQQSIHLDLAMQVTEVITHTHCCINPIIYAFVGERFRKHLRLFF... | angioblast cell migration calcium-mediated signaling cell chemotaxis chemotaxis eosinophil chemotaxis ERK1 and ERK2 cascade immune response inflammatory response mast cell chemotaxis positive regulation of angiogenesis positive regulation of cytosolic calcium ion concentration positive regulation of endothelial cell pr... |
blastocyst formation in utero embryonic development maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) rRNA processing stem cell proliferation trophectodermal cell differentiation | apical part of cell; cell projection; chromosome; cytoplasm; cytoplasmic microtubule; intracellular membrane-bounded organelle; nucleolus; nucleoplasm; perinuclear region of cytoplasm; preribosome, small subunit precursor | snoRNA binding | Mus musculus | Cytoplasm Methylation Nucleus Phosphoprotein Reference proteome Ribosome biogenesis | MPKFKVTRGA | MPKFKVTRGASNREKHAPLAEQILAGNAVRAGTREKRRGREVEEEEEYVGPRLSRRILQQARQQQEELETDHGAGDRSAPPRERATRLGPGLPQDGSDEEDEEWPTLEKAAKMAGVDHQAEVIVDPEDERAIEMFMNKNPPVRRTLADIIMEKLTEKQTEVETVMSEVSGFPMPQLDPRVLEVYRGVREVLCKYRSGKLPKAFKVIPALSNWEQILYVTEPEAWTAAAMYQATRIFASNLKERMAQRFYNLVLLPRVRDDIAEYKRLNFHLYMALKKALFKPGAWFKGILIPLCESGTCTLREAIIVGSIITKCSIPVLH... | blastocyst formation in utero embryonic development maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) rRNA processing stem cell proliferation trophectodermal cell differentiation apical part of cell; cell projection; chromosome; cytoplasm; cytoplasmic microtubule; intracellular me... |
dark adaptation dopamine receptor signaling pathway G protein-coupled receptor signaling pathway intracellular signal transduction light adaption negative regulation of signal transduction nervous system development regulation of calcium ion export across plasma membrane regulation of G protein-coupled receptor signali... | cytoplasm; glutamatergic synapse; neuron projection; plasma membrane; postsynaptic density membrane; presynaptic membrane | GTPase activator activity | Mus musculus | 3D-structure Alternative splicing Membrane Phosphoprotein Reference proteome Sensory transduction Signal transduction inhibitor Vision | MTIRHQGQQY | MTIRHQGQQYRPRMAFLQKIEALVKDMQNPETGVRMHNQRVLVTSVPHAMTGGDVLQWITQRLWISNLEAQNLGNFIVKYGYIYPLQDPKNLILKPDSSLYRFQTPYFWPTQQWPAEDTDYAIYLAKRNIKKKGILEEYEKENYDFLNKKINYKWDFVIMQAKEQYRTGKERNKADRYALDCQEKAYWLVHRSPPGMNNVLDYGLDRVTNPNEVKKQTVTAVRKEIMYYQQALMRSTVKSSVSLGGIVKYSEQFSSNDAIMSGCLPSNPWITDDTQFWDLNAKLVEIPTKMRVERWAFNFSELIRDPKGRQSFQYFLKKE... | dark adaptation dopamine receptor signaling pathway G protein-coupled receptor signaling pathway intracellular signal transduction light adaption negative regulation of signal transduction nervous system development regulation of calcium ion export across plasma membrane regulation of G protein-coupled receptor signali... |
G protein-coupled receptor signaling pathway intracellular signal transduction negative regulation of G protein-coupled receptor signaling pathway positive regulation of potassium ion transmembrane transport regulation of G protein-coupled receptor signaling pathway regulation of postsynaptic membrane potential | cytoplasm; cytosol; dendrite terminus; glutamatergic synapse; neuron projection; nuclear envelope; nucleus; plasma membrane; postsynaptic membrane; presynapse; protein-containing complex | G-protein alpha-subunit binding G-protein beta-subunit binding GTPase activator activity | Mus musculus | Cell membrane Cytoplasm GTPase activation Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome Signal transduction inhibitor Ubl conjugation | MAQGNNYGQT | MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGSDIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNCWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKKRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSHSPTHTPTPETKPPTEDELHQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYVEYDPFLVPPDPSNPWLSDDTTFWELEASK... | G protein-coupled receptor signaling pathway intracellular signal transduction negative regulation of G protein-coupled receptor signaling pathway positive regulation of potassium ion transmembrane transport regulation of G protein-coupled receptor signaling pathway regulation of postsynaptic membrane potential cytopla... |
apoptotic process cell cycle double-strand break repair negative regulation of ubiquitin-dependent protein catabolic process phosphorylation regulation of cell cycle regulation of chromosome separation spermatogenesis Wnt signaling pathway | acrosomal vesicle; chromatin; cytosol; nucleus; PcG protein complex; protein kinase CK2 complex | ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Mus musculus | Acetylation Apoptosis ATP-binding Cell cycle Cytoplasm Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transcription Transcription regulation Transferase Wnt signaling pathway | MPGPAAGSRA | MPGPAAGSRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGTDELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAM... | apoptotic process cell cycle double-strand break repair negative regulation of ubiquitin-dependent protein catabolic process phosphorylation regulation of cell cycle regulation of chromosome separation spermatogenesis Wnt signaling pathway acrosomal vesicle; chromatin; cytosol; nucleus; PcG protein complex; protein kin... |
actin filament organization focal adhesion assembly negative regulation of focal adhesion assembly negative regulation of stress fiber assembly positive regulation of GTPase activity signal transduction | actin cytoskeleton; cytoplasm; cytosol | GTPase activator activity phospholipase activator activity phospholipase binding SH3 domain binding | Mus musculus | Alternative splicing Cytoplasm GTPase activation Phosphoprotein Reference proteome SH3-binding | MSAQSLLHSV | MSAQSLLHSVFSCSSPASGGTASAKGFSKRKLRQTRSLDPALIGGCGSEMGAEGGLRGSTVSRLHSPQLLAEGLGSRLASSPRSQHLRATRFQTPRPLCSSFSTPSTPQEKSPSGSFHFDYEVPLSRSGLKKSMAWDLPSVLAGSGSASSRSPASILSSSGGGPNGIFSSPRRWLQQRKFQPPPNSRSHPYVVWRSEGDFTWNSMSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCDLGCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDLQREEQKDASSDFVSSLLPF... | actin filament organization focal adhesion assembly negative regulation of focal adhesion assembly negative regulation of stress fiber assembly positive regulation of GTPase activity signal transduction actin cytoskeleton; cytoplasm; cytosol GTPase activator activity phospholipase activator activity phospholipase bindi... |
anatomical structure morphogenesis BMP signaling pathway bone development cartilage development cell differentiation cellular response to organic cyclic compound hindbrain development midbrain development Mullerian duct regression positive regulation of cell differentiation positive regulation of DNA-templated transcri... | cytoplasm; heteromeric SMAD protein complex; nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific I-SMAD binding metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding | Rattus norvegicus | Cytoplasm DNA-binding Metal-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Zinc | MHPSTPISSL | MHPSTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQSLGPAPPSSPGHVFPQSPCPTSYPQSPGSPSESDSPYQHSDFRPVCYEEPLHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFV... | anatomical structure morphogenesis BMP signaling pathway bone development cartilage development cell differentiation cellular response to organic cyclic compound hindbrain development midbrain development Mullerian duct regression positive regulation of cell differentiation positive regulation of DNA-templated transcri... |
dephosphorylation endoderm formation negative regulation of DNA-templated transcription negative regulation of MAPK cascade negative regulation of vasoconstriction peptidyl-threonine dephosphorylation peptidyl-tyrosine dephosphorylation positive regulation of cerebral blood circulation | cytoplasm; nucleus | MAP kinase tyrosine phosphatase activity MAP kinase tyrosine/serine/threonine phosphatase activity myosin phosphatase activity phosphatase activity protein tyrosine/serine/threonine phosphatase activity protein tyrosine/threonine phosphatase activity | Rattus norvegicus | Hydrolase Nucleus Protein phosphatase Reference proteome | MKVTSLDGRR | MKVTSLDGRRLRKMLRKEAEARCVVLDCRPYLAFAASSVRGSLNVNLNSVVLRRARGGAVSARYVLADEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLSAGPRVYFLKGGYETFYSQYPECCVDAKPISQEKLEGERGLLSQCGKPILSVAYRPAYDQGGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACTTHLHYKWIPVEDSHTADISSHFQEAIDFIDCVREEGGKVLVHCEAGVSRSPTICMAYLMKTKQFRLKEAFEYIKQRRSVVSPNFGFMGQLLQYESEILPS... | dephosphorylation endoderm formation negative regulation of DNA-templated transcription negative regulation of MAPK cascade negative regulation of vasoconstriction peptidyl-threonine dephosphorylation peptidyl-tyrosine dephosphorylation positive regulation of cerebral blood circulation cytoplasm; nucleus MAP kinase tyr... |
cell-cell signaling chemical synaptic transmission neuronal action potential visual perception | connexin complex; gap junction; synapse | gap junction channel activity | Mus musculus | Cell junction Cell membrane Gap junction Membrane Reference proteome Transmembrane Transmembrane helix | MGEWTILERL | MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDPAESIGGPGGTGGGGSGGSKREDKKLQNAIVNGVLQNTETTSKETEPDCLEVKELTPHPSGLRTAARSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEVECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIKLAVRGAQAKRKSVYEIRNKDLPRVSVPNFGRTQSSDSAY... | cell-cell signaling chemical synaptic transmission neuronal action potential visual perception connexin complex; gap junction; synapse gap junction channel activity Mus musculus Cell junction Cell membrane Gap junction Membrane Reference proteome Transmembrane Transmembrane helix MGEWTILERL MGEWTILERLLEAAVQQHSTMIGRILLT... |
membrane repolarization during action potential potassium ion transmembrane transport potassium ion transport regulation of heart rate by cardiac conduction regulation of ventricular cardiac muscle cell membrane repolarization | monoatomic ion channel complex | inward rectifier potassium channel activity potassium channel activity protein-containing complex binding voltage-gated potassium channel activity | Rattus norvegicus | Ion channel Ion transport Membrane Potassium Potassium channel Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel | MPVRRGHVAP | MPVRRGHVAPQNTYLDTIIRKFEGQSRKFLIANAQMENCAIIYCNDGFCELFGYSRVEVMQRPCTCDFLTGPNTPSSAVSRLAQALLGAEECKVDILYYRKDASSFRCLVDVVPVKNEDGAVIMFILNFEDLAQLLAKSSSRSLTQRLLSHSFLGSEGSHSRPSGQGPGPGRGKYRTVSQIPQFTLNFVEFNLEKHRSGSTTEIEIIAPHKVVERTQNVTEKVTQVLSLGADVLPEYKLQAPRIHRGTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLSDQDESQRGTCGYTCSPLTVVDLIVDIMFVVDIVINFR... | membrane repolarization during action potential potassium ion transmembrane transport potassium ion transport regulation of heart rate by cardiac conduction regulation of ventricular cardiac muscle cell membrane repolarization monoatomic ion channel complex inward rectifier potassium channel activity potassium channel ... |
endocytosis endosome to lysosome transport endosome transport via multivesicular body sorting pathway extrinsic apoptotic signaling pathway via death domain receptors G protein-coupled receptor signaling pathway glucose import Golgi to endosome transport Golgi to lysosome transport intracellular protein transport maint... | cell surface; cerebellar climbing fiber to Purkinje cell synapse; clathrin-coated pit; clathrin-coated vesicle; cytoplasmic vesicle; cytoplasmic vesicle membrane; cytosol; dendrite; early endosome; endoplasmic reticulum membrane; endosome membrane; Golgi apparatus; Golgi cisterna membrane; lysosomal membrane; lysosome;... | enzyme binding G protein-coupled neurotensin receptor activity nerve growth factor binding nerve growth factor receptor activity neurotensin receptor activity, non-G protein-coupled retromer complex binding | Rattus norvegicus | Cell membrane Cleavage on pair of basic residues Developmental protein Differentiation Direct protein sequencing Disulfide bond Endocytosis Endoplasmic reticulum Endosome Glycoprotein Golgi apparatus Lipoprotein Lysosome Membrane Nucleus Osteogenesis Palmitate Phosphoprotein Receptor Reference proteome Repeat Signal Tr... | MERPRGAADG | MERPRGAADGLLRWPLGLLLLLQLLPPAAVGQDRLDAPPPPAPPLLRWAGPVGVSWGLRAAAPGGPVPRAGRWRRGAPAEDQDCGRLPDFIAKLTNNTHQHVFDDLSGSVSLSWVGDSTGVILVLTTFQVPLVIVSFGQSKLYRSEDYGKNFKDITNLINNTFIRTEFGMAIGPENSGKVILTAEVSGGSRGGRVFRSSDFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALSTENGLWVSKNFGEKWEEIHKAVCLAKWGPNNIIFFTTHVNGSCKADLGALELWRTSDLGKTFKTIGVKIYSFGLGGRFLFASVMADKD... | endocytosis endosome to lysosome transport endosome transport via multivesicular body sorting pathway extrinsic apoptotic signaling pathway via death domain receptors G protein-coupled receptor signaling pathway glucose import Golgi to endosome transport Golgi to lysosome transport intracellular protein transport maint... |
bone maturation cholesterol metabolic process membrane protein intracellular domain proteolysis mitotic G2 DNA damage checkpoint signaling positive regulation of transcription by RNA polymerase II protein maturation response to endoplasmic reticulum stress | cytoplasm; Golgi membrane | metal ion binding metalloendopeptidase activity RNA polymerase II-specific DNA-binding transcription factor binding transcription regulator activator activity | Cricetulus griseus | Cholesterol metabolism Cytoplasm Glycoprotein Golgi apparatus Hydrolase Lipid metabolism Membrane Metal-binding Metalloprotease Protease Steroid metabolism Sterol metabolism Transmembrane Transmembrane helix Zinc | MIPVSLVVVV | MIPVSLVVVVVGGWTAVYLADLVLKSSVYFKHSYEDWLEKNGLSISPFHIRWQTSVFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSSSSSSSSSSSSSSSSSIHNEQVLQVVVPGINLPVNQLTYFFAAVLISGVVHEIGHGIAAIREQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQIGYCISASTLQQLSFPVRAYKRLD... | bone maturation cholesterol metabolic process membrane protein intracellular domain proteolysis mitotic G2 DNA damage checkpoint signaling positive regulation of transcription by RNA polymerase II protein maturation response to endoplasmic reticulum stress cytoplasm; Golgi membrane metal ion binding metalloendopeptidas... |
cellular response to glucose starvation intracellular signal transduction negative regulation of TOR signaling peptidyl-serine phosphorylation protein autophosphorylation protein phosphorylation spermatid development | acrosomal vesicle; centriole; cytoplasm; nucleotide-activated protein kinase complex | ATP binding magnesium ion binding protein serine kinase activity protein serine/threonine kinase activity protein-containing complex binding | Mus musculus | ATP-binding Cytoplasm Cytoplasmic vesicle Cytoskeleton Developmental protein Differentiation Kinase Magnesium Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Spermatogenesis Transferase Ubl conjugation | MDDAAVLRKK | MDDAAVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHRSIIKTYEIFETSDGRIYIVMELGVQGDLLEFIKCRGALHEDVARKMFRQLSSAVKYCHDLDVVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDGSGRIVLSKTFCGSAAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIKKMLRIQKEHRVDFPRSKNLTGECKDLIYRILQPDVNRRLHIDEILSHSWLQPPKPKAMSSASFKREGEGKYRADCKLDTRPGSRPEHRPDHKLATKPQ... | cellular response to glucose starvation intracellular signal transduction negative regulation of TOR signaling peptidyl-serine phosphorylation protein autophosphorylation protein phosphorylation spermatid development acrosomal vesicle; centriole; cytoplasm; nucleotide-activated protein kinase complex ATP binding magnes... |
blastocyst hatching cell cycle cell differentiation cellular response to glucose starvation cellular response to hypoxia chromosome organization circadian rhythm determination of adult lifespan DNA damage response energy homeostasis epigenetic programming in the zygotic pronuclei heterochromatin formation methylation n... | chromatin silencing complex; chromosome, centromeric region; eNoSc complex; heterochromatin; nuclear lamina; nucleolus; nucleoplasm; nucleus; rDNA heterochromatin | histone H3K9 methyltransferase activity histone H3K9 trimethyltransferase activity histone H3K9me2 methyltransferase activity histone methyltransferase activity protein methyltransferase activity RNA polymerase II transcription regulatory region sequence-specific DNA binding S-adenosylmethionine-dependent methyltransfe... | Mus musculus | Acetylation Alternative splicing Biological rhythms Cell cycle Centromere Chromatin regulator Chromosome Differentiation Metal-binding Methyltransferase Nucleus Phosphoprotein Reference proteome Repressor rRNA processing S-adenosyl-L-methionine Transcription Transcription regulation Transferase Ubl conjugation Zinc | MAENLKGCSV | MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGVSKKNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSENTWEPRQNLKCIRVLKQFHKDLERELVRRHRRSKPPRHLDPNLANYLVQKAKQRRALQRWEQELNAKRSHLGRITVENEVDLDGPPRSFVYINEYRVGEGITLNQVAVGCECQDCLLAPTGGCCPGASLHKFAYNDQGQVRLKAGQPIYECNSRCCCGYDCPNRVVQKGIRYDLCIFRTNDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISH... | blastocyst hatching cell cycle cell differentiation cellular response to glucose starvation cellular response to hypoxia chromosome organization circadian rhythm determination of adult lifespan DNA damage response energy homeostasis epigenetic programming in the zygotic pronuclei heterochromatin formation methylation n... |
cellular response to nitric oxide cGMP biosynthetic process cGMP-mediated signaling nitric oxide-cGMP-mediated signaling pathway response to oxygen levels trans-synaptic signaling by nitric oxide, modulating synaptic transmission | cytoplasm; cytosol; glutamatergic synapse; guanylate cyclase complex, soluble; presynaptic active zone; presynaptic active zone cytoplasmic component; protein-containing complex | adenylate cyclase activity cytidylate cyclase activity GTP binding guanylate cyclase activity heme binding Hsp90 protein binding ion binding metal ion binding protein-containing complex binding | Mus musculus | cGMP biosynthesis Cytoplasm GTP-binding Heme Iron Lyase Metal-binding Nucleotide-binding Reference proteome | MYGFVNHALE | MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRNLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGAEISCLRLKGQMIYLPEADSIL... | cellular response to nitric oxide cGMP biosynthetic process cGMP-mediated signaling nitric oxide-cGMP-mediated signaling pathway response to oxygen levels trans-synaptic signaling by nitric oxide, modulating synaptic transmission cytoplasm; cytosol; glutamatergic synapse; guanylate cyclase complex, soluble; presynaptic... |
DNA geometric change innate immune response negative regulation of B cell differentiation negative regulation of myeloid cell differentiation regulation of transcription by RNA polymerase II | chromosome; cytoplasm; nucleus | DNA binding DNA binding, bending four-way junction DNA binding RNA binding | Mus musculus | Acetylation Chromosome Cytoplasm Disulfide bond DNA-binding Immunity Innate immunity Nucleus Oxidation Phosphoprotein Reference proteome Repeat Transcription Transcription regulation | MAKGDPKKPK | MAKGDPKKPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSSKEKSKFDEMAKADKVRYDREMKDYGPAKGGKKKKDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGEMWNNLSDNEKQPYVTKAAKLKEKYEKDVADYKSKGKFDGAKGPAKVARKKVEEEEEEEEEEEEEEEEEEDE | DNA geometric change innate immune response negative regulation of B cell differentiation negative regulation of myeloid cell differentiation regulation of transcription by RNA polymerase II chromosome; cytoplasm; nucleus DNA binding DNA binding, bending four-way junction DNA binding RNA binding Mus musculus Acetylatio... |
exocytosis G protein-coupled receptor signaling pathway glucose homeostasis intracellular protein transport negative regulation of G protein-coupled receptor signaling pathway positive regulation of insulin secretion positive regulation of protein secretion regulation of calcium ion-dependent exocytosis response to xen... | presynapse; secretory granule; synapse; transport vesicle membrane | LIM domain binding metal ion binding small GTPase binding | Rattus norvegicus | Cytoplasm Cytoplasmic vesicle Exocytosis Membrane Metal-binding Phosphoprotein Reference proteome Zinc Zinc-finger | MADTIFSSGN | MADTIFSSGNDQWVCPNDRQLALRAKLQTGWSVHTYQTEKQRRTQCLSPGEVEVILQVIQRAERLDILEQQRIGRLVERLETMQKNVMGNGVSQCLLCGEMLGFLGSSSVFCKDCRKKVCTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHFRPLPVEPTEPQPQSAEVSRVYTWARGRVVSSDSDSDSDLSSSSLEDRPMPSGIKGTKYDKPRGDSGGSMESPRMGPARPPSHLSGSQSSLGSETGAGATDPQGGTLPRPEPRVSGKRHTWATTHY | exocytosis G protein-coupled receptor signaling pathway glucose homeostasis intracellular protein transport negative regulation of G protein-coupled receptor signaling pathway positive regulation of insulin secretion positive regulation of protein secretion regulation of calcium ion-dependent exocytosis response to xen... |
cell-cell adhesion heterotypic cell-cell adhesion negative regulation of cell population proliferation negative regulation of interleukin-6 production negative regulation of macrophage activation negative regulation of macrophage migration negative regulation of matrix metallopeptidase secretion negative regulation of ... | axon; cell body; cell surface; neuron projection; neuronal cell body; plasma membrane | cell-cell adhesion mediator activity protein binding involved in heterotypic cell-cell adhesion | Mus musculus | 3D-structure Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Immunoglobulin domain Membrane Reference proteome Signal Transmembrane Transmembrane helix | MGSLVFRRPF | MGSLVFRRPFCHLSTYSLIWGMAAVALSTAQVEVVTQDERKALHTTASLRCSLKTSQEPLIVTWQKKKAVSPENMVTYSKTHGVVIQPAYKDRINVTELGLWNSSITFWNTTLEDEGCYMCLFNTFGSQKVSGTACLTLYVQPIVHLHYNYFEDHLNITCSATARPAPAISWKGTGTGIENSTESHFHSNGTTSVTSILRVKDPKTQVGKEVICQVLYLGNVIDYKQSLDKGFWFSVPLLLSIVSLVILLVLISILLYWKRHRNQERGESSQGMQRMK | cell-cell adhesion heterotypic cell-cell adhesion negative regulation of cell population proliferation negative regulation of interleukin-6 production negative regulation of macrophage activation negative regulation of macrophage migration negative regulation of matrix metallopeptidase secretion negative regulation of ... |
cadmium ion transmembrane transport cellular response to hypoxia cellular response to iron ion cellular response to tumor necrosis factor cobalt ion transport copper ion import across plasma membrane copper ion transport dendrite morphogenesis erythrocyte development establishment of localization in cell heme biosynthe... | apical part of cell; apical plasma membrane; basal part of cell; brush border membrane; cell surface; cytoplasm; cytoplasmic vesicle; early endosome; early endosome membrane; endosome; extracellular vesicle; late endosome; late endosome membrane; lysosomal membrane; mitochondrial outer membrane; nucleus; paraferritin c... | cadmium ion binding cadmium ion transmembrane transporter activity cobalt ion binding cobalt ion transmembrane transporter activity copper ion binding copper ion transmembrane transporter activity ferrous iron transmembrane transporter activity inorganic cation transmembrane transporter activity iron ion binding iron i... | Rattus norvegicus | Alternative splicing Cell membrane Disease variant Endosome Glycoprotein Golgi apparatus Ion transport Iron Iron transport Lysosome Membrane Mitochondrion Mitochondrion outer membrane Phosphoprotein Reference proteome Symport Transmembrane Transmembrane helix Transport Ubl conjugation | MVLDPEEKIP | MVLDPEEKIPDDGASGDHGDSASLGAINPAYSNSSLPHSTGDSEEPFTTYFDEKIPIPEEEYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWVLLLATIVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRIILWLMVELAIIGSDMQEVIGSAIAINLLSAGRVPLYGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLRGMFVPSCSGCHTPQVEQAVGIVGAVIMPHNMYLHSALVKSRQVNRANKQEVREANKYFFIESCIALFVSFIINVFVVSVFAE... | cadmium ion transmembrane transport cellular response to hypoxia cellular response to iron ion cellular response to tumor necrosis factor cobalt ion transport copper ion import across plasma membrane copper ion transport dendrite morphogenesis erythrocyte development establishment of localization in cell heme biosynthe... |
galactosylceramide biosynthetic process lipid glycosylation oligosaccharide biosynthetic process protein O-linked glycosylation | Golgi membrane; membrane | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity | Mus musculus | Glycoprotein Glycosyltransferase Golgi apparatus Lipid metabolism Manganese Membrane Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MASKVSCLYV | MASKVSCLYVLTVVCWASALWYLSITRPTSSYTGSKPFSHLTVARKNFTFGNIRTRPINPHSFEFLINEPNKCEKNIPFLVILISTTHKEFDARQAIRETWGDENNFKGIKIATLFLLGKNADPVLNQMVEQESQIFHDIIVEDFIDSYHNLTLKTLMGMRWVATFCSKAKYVMKTDSDIFVNMDNLIYKLLKPSTKPRRRYFTGYVINGGPIRDVRSKWYMPRDLYPDSNYPPFCSGTGYIFSADVAELIYKTSLHTRLLHLEDVYVGLCLRKLGIHPFQNSGFNHWKMAYSLCRYRRVITVHQISPEEMHRIWNDMSS... | galactosylceramide biosynthetic process lipid glycosylation oligosaccharide biosynthetic process protein O-linked glycosylation Golgi membrane; membrane glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity Mus musculus ... |
galactosylceramide biosynthetic process oligosaccharide biosynthetic process protein O-linked glycosylation | Golgi membrane; membrane | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity | Mus musculus | Glycoprotein Glycosyltransferase Golgi apparatus Lipid metabolism Manganese Membrane Reference proteome Signal-anchor Transferase Transmembrane Transmembrane helix | MLQWRRRHCC | MLQWRRRHCCFAKMTWSPKRSLLRTPLTGVLSLVFLFAMFLFFNHHDWLPGRPGFKENPVTYTFRGFRSTKSETNHSSLRTIWKEVAPQTLRPHTASNSSNTELSPQGVTGLQNTLSANGSIYNEKGTGHPNSYHFKYIINEPEKCQEKSPFLILLIAAEPGQIEARRAIRQTWGNETLAPGIQIIRVFLLGISIKLNGYLQHAIQEESRQYHDIIQQEYLDTYYNLTIKTLMGMNWVATYCPHTPYVMKTDSDMFVNTEYLIHKLLKPDLPPRHNYFTGYLMRGYAPNRNKDSKWYMPPDLYPSERYPVFCSGTGYVFS... | galactosylceramide biosynthetic process oligosaccharide biosynthetic process protein O-linked glycosylation Golgi membrane; membrane glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity Mus musculus Glycoprotein Glycosy... |
angiogenesis cell differentiation extrinsic apoptotic signaling pathway immune response positive regulation of extrinsic apoptotic signaling pathway positive regulation of protein catabolic process | extracellular region; extracellular space; perinuclear region of cytoplasm; plasma membrane | cytokine activity receptor ligand activity tumor necrosis factor receptor binding | Mus musculus | Angiogenesis Apoptosis Cell membrane Cleavage on pair of basic residues Cytokine Developmental protein Differentiation Disulfide bond Glycoprotein Membrane Reference proteome Secreted Signal-anchor Transmembrane Transmembrane helix | MAARRSQRRR | MAARRSQRRRGRRGEPGTALLAPLVLSLGLALACLGLLLVVVSLGSWATLSAQEPSQEELTAEDRREPPELNPQTEESQDVVPFLEQLVRPRRSAPKGRKARPRRAIAAHYEVHPRPGQDGAQAGVDGTVSGWEETKINSSSPLRYDRQIGEFTVIRAGLYYLYCQVHFDEGKAVYLKLDLLVNGVLALRCLEEFSATAASSPGPQLRLCQVSGLLPLRPGSSLRIRTLPWAHLKAAPFLTYFGLFQVH | angiogenesis cell differentiation extrinsic apoptotic signaling pathway immune response positive regulation of extrinsic apoptotic signaling pathway positive regulation of protein catabolic process extracellular region; extracellular space; perinuclear region of cytoplasm; plasma membrane cytokine activity receptor lig... |
9-cis-retinoic acid biosynthetic process positive regulation of retinoic acid biosynthetic process retinoic acid metabolic process retinoid metabolic process retinol metabolic process steroid metabolic process | endoplasmic reticulum lumen; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; organelle membrane | 11-cis-retinol dehydrogenase androstan-3-alpha,17-beta-diol dehydrogenase activity androsterone dehydrogenase activity identical protein binding NAD-retinol dehydrogenase activity | Mus musculus | Endoplasmic reticulum Lipid metabolism Membrane Microsome NAD Oxidoreductase Reference proteome Steroid metabolism Transmembrane Transmembrane helix | MWLYLVALVG | MWLYLVALVGLWTLLRFFRVRQVVSHLQDKYVFITGCDSGFGTLLARQLDRRGMRVLAACLTEKGAEELRNKTSDRLETVILDVTKTESIVTATQWVKEHVGNRGLWGLVNNAGISTPSGPNEWMKKQDFAHVLDVNLLGMIEVTLSMLPLVRKARGRVVNVSSVMGRVSLFGGGYCISKYGVEAFSDSLRRELSYFGVKVAIIEPGFFLTGVTSSARLCSNTQMLWDQTSSEIREIYGEKYLASYLKRLNKLDKRCNKDLSGVTDCMEHALTACHPRTRYSAGWDAKLFYLPLSYLPTFLVDALLYWTSLKPEKAL | 9-cis-retinoic acid biosynthetic process positive regulation of retinoic acid biosynthetic process retinoic acid metabolic process retinoid metabolic process retinol metabolic process steroid metabolic process endoplasmic reticulum lumen; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; organel... |
cellular response to hypoxia cellular response to zinc ion cochlea development monoatomic ion transmembrane transport negative regulation of cytosolic calcium ion concentration potassium ion transmembrane transport potassium ion transport regulation of resting membrane potential response to xenobiotic stimulus stabiliz... | plasma membrane | monoatomic ion channel activity open rectifier potassium channel activity outward rectifier potassium channel activity potassium ion leak channel activity S100 protein binding | Rattus norvegicus | Cell membrane Glycoprotein Ion channel Ion transport Membrane Potassium Potassium channel Potassium transport Reference proteome Transmembrane Transmembrane helix Transport | MKRQNVRTLA | MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPEMIERQRLELRQLELRARYNLSEGGYEELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERINTFVRYLLHRAKRGLGMRHAEVSMANMVLIGFVSCISTLCIGAAAFSYYERWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLVVLRFMTMNAEDEKRDAEHRALLTHNGQAGGLGGLSCLSGSLGDGVRPRDPVTCAAAAGGMGVGVGVGGSGFRNVYAEM... | cellular response to hypoxia cellular response to zinc ion cochlea development monoatomic ion transmembrane transport negative regulation of cytosolic calcium ion concentration potassium ion transmembrane transport potassium ion transport regulation of resting membrane potential response to xenobiotic stimulus stabiliz... |
cell differentiation negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of gene expression positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription ... | intermediate filament cytoskeleton; nuclear body; nucleoplasm; transcription regulator complex | DNA-binding transcription activator activity, RNA polymerase II-specific nuclear receptor activity nuclear receptor binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding ... | Mus musculus | Activator Alternative splicing DNA-binding Metal-binding Nucleus Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MRPEESWSRV | MRPEESWSRVGLVQCEEADSALEEPINVEEEDGGLQICRVCGDKANGYHFNVMTCEGCKGFFRRAMKRNVRLRCPFRKGTCEITRKTRRQCQACRLRKCLESGMKKEMIMSDAAVEQRRALIKRKKREKIEAPPPGGQGLTEEQQALIQELMDAQMQTFDTTFSHFKDFRLPAVFHSGCELPEFLQASLLEDPATWSQIMKDRVPMKISLQLRGEDGSIWNYQPPSKSDGKEIIPLLPHLADVSTYMFKGVINFAKVISYFRDLPIEDQISLLKGATFEMCILRFNTMFDTETGTWECGRLAYCFEDPNGGFQKLLLDPL... | cell differentiation negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of gene expression positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription ... |
endocytosis endosomal transport | clathrin-coated pit; cytoplasm; cytosol; intracellular membrane-bounded organelle; nucleoplasm; plasma membrane | calcium ion binding SH3 domain binding | Mus musculus | 3D-structure Alternative splicing Calcium Coated pit Coiled coil Membrane Metal-binding Phosphoprotein Reference proteome Repeat | MEGLTLSDAE | MEGLTLSDAEQKYYSDLFSYCDIESTKKVVVNGRVLELFRAAQLPNDVVLQIMELCGATRLGYFGRSQFYIALKLVAVAQSGFPLRVESINTVKDLPLPRFVASKNEQESRLAASYSSDSENQGSYSGVIPPPPGRGQVKKGPGSHDAVQPRPSAEQQEPVSPVVSPQQSPPTSPHTWRKHSRHPSGGNSERPLTGPGPFWSPFGDAQAGSSAGDAVWSGQSPPPPQDNWVSFADTPPTSALLTMHPASVQDQTTVRTVASAATANEIRRQSSSYEDPWKITDEQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTKSKLPI... | endocytosis endosomal transport clathrin-coated pit; cytoplasm; cytosol; intracellular membrane-bounded organelle; nucleoplasm; plasma membrane calcium ion binding SH3 domain binding Mus musculus 3D-structure Alternative splicing Calcium Coated pit Coiled coil Membrane Metal-binding Phosphoprotein Reference proteome Re... |
cell cycle negative regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | DNA replication factor A complex; MLL1 complex; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex | DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA b... | Mus musculus | Cell cycle DNA-binding Nucleus Reference proteome Repressor Transcription Transcription regulation | MSQQRTARRQ | MSQQRTARRQPSLLVDPAQETVRRRCRDPINVENLLPSKIRINLEENVQYVSMRKALKVKRPRFDVSLVYLTRKFMDLVRSAPGGILDLNKVATKLGVRKRRVYDITNVLDGIELVEKKSKNHIRWIGSDLNNFGAAPQQKKLQAELSDLSAMEDALDELIKDCAQQLLELTDDKENERLAYVTYQDIHGIQAFHEQIVIAVKAPEETRLDVPAPREDSITVHIRSTKGPIDVYLCEVEQNHSNGKTNDGIGASPSKSSHPQCPEKEDEPPQ | cell cycle negative regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II DNA replication factor A complex; MLL1 complex; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex DNA binding DNA-binding transcription factor activity DNA-binding transcription fa... |
endosome organization exocytosis extracellular matrix disassembly Golgi to plasma membrane transport protein localization protein transport | cell leading edge; exocyst; growth cone; late endosome; perinuclear region of cytoplasm | phosphatidylinositol binding small GTPase binding | Rattus norvegicus | 3D-structure Cell projection Cytoplasm Direct protein sequencing Exocytosis Phosphoprotein Protein transport Reference proteome Transport | MSDSGASRLR | MSDSGASRLRRQLESGGFEARLYVKQLSQQSDGDRDLQEHRQRVQALAEETAQNLKRNVYQNYRQFIETAREISYLESEMYQLSHLLTEQKSSLESIPLALLPAAAAGASTGEDTAGAGPRERGAAQAGFLPGPAGVPREGPGTGEEGKQRTLTTLLEKVEGCRDLLETPGQYLVYNGDLVEYEADHMAQLQRVHGFLMNDCLLVATWLPQRRGMYRYNALYPLDRLAVVNVKDNPPMKDMFKLLMFPESRIFQAENAKIKREWLEVLEETKRALSDKRRREQEEAAALRAPPPVTSKGSNPFEDEAEEELATPEAEEEK... | endosome organization exocytosis extracellular matrix disassembly Golgi to plasma membrane transport protein localization protein transport cell leading edge; exocyst; growth cone; late endosome; perinuclear region of cytoplasm phosphatidylinositol binding small GTPase binding Rattus norvegicus 3D-structure Cell projec... |
activation-induced cell death of T cells extrinsic apoptotic signaling pathway positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | cytoplasm; mitochondrion; nucleoplasm | CD27 receptor binding tumor necrosis factor receptor binding virus receptor activity zinc ion binding | Mus musculus | Alternative splicing Apoptosis Cytoplasm Metal-binding Nucleus Phosphoprotein Reference proteome Zinc | MPKRSCPFAD | MPKRSCPFADAAPLQLKVHVGLKELSHGVFAERYSREVFERTKQLLFQGARAYRDHISSEDCSVNHLQESLKSGVVGAPQPARGQMLIGPDGRLTRCQAQASEGGLPRTAPIACSSCMRSVDGKAVCSQCERALCGQCVYTCWGCGALACVLCGLADYADDGEKTLCTSCAMFEA | activation-induced cell death of T cells extrinsic apoptotic signaling pathway positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway cytoplasm; mitochondrion; nucleoplasm CD27 receptor binding tumor necrosis factor receptor binding virus receptor activity zinc ion ... |
cellular response to low-density lipoprotein particle stimulus cytokine-mediated signaling pathway epidermal growth factor receptor signaling pathway intracellular signal transduction negative regulation of endothelial cell activation negative regulation of epidermal growth factor-activated receptor activity negative r... | cytoplasm; phosphatidylinositol 3-kinase complex | 1-phosphatidylinositol-3-kinase regulator activity epidermal growth factor receptor binding kinase inhibitor activity receptor tyrosine kinase binding | Mus musculus | 3D-structure Growth regulation Reference proteome SH2 domain Signal transduction inhibitor Ubl conjugation pathway | MDKVGKMWNN | MDKVGKMWNNLKYRCQNLFSHEGGSRNENVEMNPNRCPSVKEKSISLGEAAPQQESSPLRENVALQLGLSPSKTFSRRNQNCAAEIPQVVEISIEKDSDSGATPGTRLARRDSYSRHAPWGGKKKHSCSTKTQSSLDTEKKFGRTRSGLQRRERRYGVSSMQDMDSVSSRAVGSRSLRQRLQDTVGLCFPMRTYSKQSKPLFSNKRKIHLSELMLEKCPFPAGSDLAQKWHLIKQHTAPVSPHSTFFDTFDPSLVSTEDEEDRLRERRRLSIEEGVDPPPNAQIHTFEATAQVNPLYKLGPKLAPGMTEISGDGSAIPQT... | cellular response to low-density lipoprotein particle stimulus cytokine-mediated signaling pathway epidermal growth factor receptor signaling pathway intracellular signal transduction negative regulation of endothelial cell activation negative regulation of epidermal growth factor-activated receptor activity negative r... |
acetyl-CoA biosynthetic process from pyruvate cellular response to fatty acid cellular response to starvation glucose homeostasis insulin receptor signaling pathway negative regulation of anoikis phosphorylation reactive oxygen species metabolic process regulation of acetyl-CoA biosynthetic process from pyruvate regula... | mitochondrial matrix; mitochondrion | ATP binding protein kinase activity pyruvate dehydrogenase (acetyl-transferring) kinase activity | Rattus norvegicus | ATP-binding Kinase Mitochondrion Nucleotide-binding Reference proteome Transferase Transit peptide | MKAARFVMRS | MKAARFVMRSASSLGNAGLVPREVELFSRYSPSPLSMKQLLDFGSENACERTSFSFLRQELPVRLANILKEIDILPEHLVNTPSVQLVKSWYIQSLMDLVEFHEKSPEDQKVLSDFVDTLVKVRNRHHNVVPTMAQGILEYKDNCTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSKTGNPSHIGSIDPNCDVVAVVEDAFECAKMLCDQYYLTSPELKLTQVNGKFPGQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENRPFLTPVEATVVLGKEDLTIKISDRGGGVPLRITDRLFSYTYSTAPTPVMD... | acetyl-CoA biosynthetic process from pyruvate cellular response to fatty acid cellular response to starvation glucose homeostasis insulin receptor signaling pathway negative regulation of anoikis phosphorylation reactive oxygen species metabolic process regulation of acetyl-CoA biosynthetic process from pyruvate regula... |
biphenyl metabolic process cellular response to antibiotic cellular response to gonadotropin stimulus cellular response to hormone stimulus hippocampus development insecticide metabolic process Leydig cell differentiation organic acid metabolic process phenol-containing compound metabolic process response to activity r... | endoplasmic reticulum | 17-beta-hydroxysteroid dehydrogenase (NADP+) activity estradiol 17-beta-dehydrogenase activity testosterone 17-beta-dehydrogenase (NADP+) activity testosterone dehydrogenase (NAD+) activity | Rattus norvegicus | Endoplasmic reticulum Lipid biosynthesis Lipid metabolism NADP Oxidoreductase Reference proteome Steroid biosynthesis | MEQFLLSVGL | MEQFLLSVGLLVCLVCLVKCVRFSRYLFLSFCKALPGSFLRSMGQWAVITGAGDGIGKAYSFELARHGLNVVLISRTLEKLQVISEEIERTTGSRVKVVQADFTREDIYDHIEEQLKGLEIGVLVNNVGMLPNLLPSHFLSTSGESQSVIHCNITSVVKMTQLVLKHMESRRRGLILNISSGVGVRPWPLYSLYSASKAFVCTFSKALNVEYRDKGIIIQVLTPYSVSTPMTKYLNTSRVTKTADEFVKESLKYVTIGAETCGCLAHEILAIILNLIPSRIFYSSTTQRFLLKQFSDYLKSNISNR | biphenyl metabolic process cellular response to antibiotic cellular response to gonadotropin stimulus cellular response to hormone stimulus hippocampus development insecticide metabolic process Leydig cell differentiation organic acid metabolic process phenol-containing compound metabolic process response to activity r... |
chromatin remodeling negative regulation of DNA-templated transcription neurogenesis nucleosome disassembly positive regulation of cell differentiation positive regulation of double-strand break repair positive regulation of myoblast differentiation positive regulation of stem cell population maintenance positive regul... | bBAF complex; brahma complex; chromatin; kinetochore; nBAF complex; npBAF complex; nuclear matrix; nucleoplasm; nucleus; RSC-type complex; SWI/SNF complex | DNA binding N-acetyltransferase activity nuclear receptor binding RNA binding | Mus musculus | Chromatin regulator Coiled coil DNA-binding Isopeptide bond Methylation Neurogenesis Nucleus Phosphoprotein Reference proteome Ubl conjugation | MSKRPSYAPP | MSKRPSYAPPPTPAPATQMPSTPGFVGYNPYSHLAYNNYRLGGNPGTNSRVTASSGITIPKPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQPAEDPDDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSMAP... | chromatin remodeling negative regulation of DNA-templated transcription neurogenesis nucleosome disassembly positive regulation of cell differentiation positive regulation of double-strand break repair positive regulation of myoblast differentiation positive regulation of stem cell population maintenance positive regul... |
bicellular tight junction assembly calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules cell adhesion cell-cell adhesion cell-cell junction assembly establishment of blood-retinal barrier maintenance of blood-brain barrier myelination negative regulation of angiogenesis negative regulation... | apicolateral plasma membrane; bicellular tight junction; cell-cell junction; cortical actin cytoskeleton; lateral plasma membrane; paranode region of axon; plasma membrane; Schmidt-Lanterman incisure; tight junction | identical protein binding structural molecule activity | Mus musculus | Cell junction Cell membrane Membrane Reference proteome Tight junction Transmembrane Transmembrane helix | MGSAALEILG | MGSAALEILGLVLCLVGWVGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYESVLALSAEVQAARALTVGAVLLALVALFVTLTGAQCTTCVAPGPVKARVALTGGALYAVCGLLALVPLCWFANIVVREFYDPTVPVSQKYELGAALYIGWAASALLMCGGGLVCCGAWVCTGRPEFSFPVKYSAPRRPTANGDYDKKNYV | bicellular tight junction assembly calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules cell adhesion cell-cell adhesion cell-cell junction assembly establishment of blood-retinal barrier maintenance of blood-brain barrier myelination negative regulation of angiogenesis negative regulation... |
actin cytoskeleton organization chaperone-mediated protein folding chorio-allantoic fusion chorion development extracellular matrix organization intermediate filament organization negative regulation of DNA-templated transcription negative regulation of inclusion body assembly protein folding protein localization to nu... | cytoplasm; cytosol; nucleoplasm; nucleus; perinuclear region of cytoplasm; Z disc | ATPase activator activity DNA binding heat shock protein binding Hsp70 protein binding identical protein binding protein folding chaperone protein-folding chaperone binding unfolded protein binding | Mus musculus | Alternative splicing Chaperone Cytoplasm Methylation Nucleus Reference proteome | MVDYYEVLGV | MVDYYEVLGVQRHASPEDIKKAYRKQALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRDIYDKYGKEGLNGGGGGGGIHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFDFFEDPFDDFFGNRRGPRGNRSRGAGSFFSTFSGFPSFGSGFPAFDTGFTPFGSLGHGGLTSFSSTSFGGSGMGNFKSISTSTKIVNGKKITTKRIVENGQERVEVEEDGQLKSLTINGVADENALAEECQRRGQPTPALAPGPAPAPVRVPSQARPLAPTPAPTPAPTPAPAPAQTPAPSVSTRPQKPPRPAPTAKLGSKSNWEDD... | actin cytoskeleton organization chaperone-mediated protein folding chorio-allantoic fusion chorion development extracellular matrix organization intermediate filament organization negative regulation of DNA-templated transcription negative regulation of inclusion body assembly protein folding protein localization to nu... |
phagocytosis, engulfment positive regulation of mast cell activation response to lipopolysaccharide response to mycotoxin response to nutrient response to testosterone response to wounding response to xenobiotic stimulus | apical plasma membrane; brush border; cell surface; extracellular space; motile cilium; phagocytic vesicle | phosphatidylserine binding virus receptor activity | Rattus norvegicus | Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Membrane Reference proteome Signal Transmembrane Transmembrane helix | MVQLQVFISG | MVQLQVFISGLLLLLPGSVDSYEVVKGVVGHPVTIPCTYSTRGGITTTCWGRGQCPYSSCQNILIWTNGYQVTYRSSGRYNIKGRISEGDVSLTIENSVDSDSGLYCCRVEIPGWFNDQKMTFSLEVKPEIPTSPPTRPTTTRPTTTRPTTISTRSTHVPTSTRVSTSTPTPEQTQTHKPEITTFYAHETTAEVTETPSYTPADWNGTVTSSEEAWNNHTVRIPLRKPQRNPTKGFYVGMSVAALLLLLLASTVVVTRYIIIRKKMGSLSFVAFHVSKSRALQNAAIVHPRAEDNIYIIEDRSRGAE | phagocytosis, engulfment positive regulation of mast cell activation response to lipopolysaccharide response to mycotoxin response to nutrient response to testosterone response to wounding response to xenobiotic stimulus apical plasma membrane; brush border; cell surface; extracellular space; motile cilium; phagocytic ... |
cellular response to osmotic stress intracellular signal transduction negative regulation of TORC1 signaling negative regulation of Wnt signaling pathway peptidyl-threonine phosphorylation protein phosphorylation protein stabilization regulation of DNA-templated transcription serine phosphorylation of STAT protein tran... | cytoplasm; nucleus | ATP binding DNA-binding transcription factor binding magnesium ion binding MAP kinase activity protein kinase activity protein serine kinase activity protein serine/threonine kinase activity SH2 domain binding ubiquitin protein ligase binding | Mus musculus | ATP-binding Cytoplasm Kinase Magnesium Metal-binding Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transcription Transcription regulation Transferase Wnt signaling pathway | MSLCGTRANA | MSLCGTRANAKMMAAYNGGTSAAAAGHHHHHHHHLPHLPPPHLHHHHHPQHHLHPGSAAAVHPVQQHTSSAAAAAAAAAAAAAMLNPGQQQPYFPSPAPGQAPGPAAAAPAQVQAAAAATVKAHHHQHSHHPQQQLDIEPDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVLSALDILQPPHIDYFEEIYVVTELMQSDLHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGLARVEELDESRHMTQEVVTQYYRAPEILMGSRHYSN... | cellular response to osmotic stress intracellular signal transduction negative regulation of TORC1 signaling negative regulation of Wnt signaling pathway peptidyl-threonine phosphorylation protein phosphorylation protein stabilization regulation of DNA-templated transcription serine phosphorylation of STAT protein tran... |
cellular response to nutrient levels fatty acid biosynthetic process import into nucleus positive regulation of gene expression | cytoplasm; cytosol; nucleoplasm; nucleotide-activated protein kinase complex; nucleus; protein-containing complex | ADP binding AMP binding AMP-activated protein kinase activity ATP binding protein kinase activity protein kinase binding protein kinase regulator activity protein-containing complex binding | Mus musculus | ATP-binding CBS domain Fatty acid biosynthesis Fatty acid metabolism Glycoprotein Lipid biosynthesis Lipid metabolism Nucleotide-binding Phosphoprotein Reference proteome Repeat | MESVAAESSP | MESVAAESSPALENEHFQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLQELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDEHDVVKGIVSLSDILQA... | cellular response to nutrient levels fatty acid biosynthetic process import into nucleus positive regulation of gene expression cytoplasm; cytosol; nucleoplasm; nucleotide-activated protein kinase complex; nucleus; protein-containing complex ADP binding AMP binding AMP-activated protein kinase activity ATP binding prot... |
axon guidance central nervous system development hippocampus development negative chemotaxis negative regulation of axon extension involved in axon guidance neural crest cell migration positive regulation of cell migration semaphorin-plexin signaling pathway | plasma membrane | chemorepellent activity semaphorin receptor binding | Mus musculus | Cell membrane Developmental protein Differentiation Disulfide bond Glycoprotein Membrane Methylation Neurogenesis Reference proteome Signal Transmembrane Transmembrane helix | MWTPRVPPPR | MWTPRVPPPRPALSFFLLLLLGVTYGLFPEEPPPLSVAPRDYLSHYPVFVGSGPGRLTAAEGAEDLNIQRVLRVNRTLFIGDRDNLYQVELEPSTSTELRYQRKLTWRSNPSDIDVCRMKGKQEGECRNFVKVLLLRDESTLFVCGSNAFNPICANYSMDTLQLLGDSISGMARCPYDPKHANVALFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEWGSHVYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGVVSLGGRPV... | axon guidance central nervous system development hippocampus development negative chemotaxis negative regulation of axon extension involved in axon guidance neural crest cell migration positive regulation of cell migration semaphorin-plexin signaling pathway plasma membrane chemorepellent activity semaphorin receptor b... |
adaptive immune response calcium-mediated signaling cellular defense response gene expression homeostasis of number of cells immune response inflammatory response integrin-mediated signaling pathway intracellular signal transduction lymphocyte homeostasis mast cell degranulation Ras protein signal transduction regulati... | cell-cell junction; COP9 signalosome; Golgi apparatus; immunological synapse; membrane; plasma membrane | protein kinase binding signaling receptor complex adaptor activity | Mus musculus | Adaptive immunity Cell membrane Immunity Lipoprotein Mast cell degranulation Membrane Palmitate Phosphoprotein Reference proteome Signal-anchor Transmembrane Transmembrane helix Ubl conjugation | MEADALSPVG | MEADALSPVGLGLLLLPFLVTLLAALCVRCRELPVSYDSTSTESLYPRSILIKPPQITVPRTPAVSYPLVTSFPPLRQPDLLPIPRSPQPLGGSHRMPSSQQNSDDANSVASYENQEPACKNVDADEDEDDYPNGYLVVLPDSSPAAVPVVSSAPVPSNPDLGDSAFSVESCEDYVNVPESEESAEASLDGSREYVNVSPEQQPVTRAELASVNSQEVEDEGEEEGVDGEEAPDYENLQELN | adaptive immune response calcium-mediated signaling cellular defense response gene expression homeostasis of number of cells immune response inflammatory response integrin-mediated signaling pathway intracellular signal transduction lymphocyte homeostasis mast cell degranulation Ras protein signal transduction regulati... |
neuron projection regeneration neurotransmitter secretion positive regulation of peptidyl-cysteine S-nitrosylation postsynaptic actin cytoskeleton organization regulation of calcium ion transmembrane transport via high voltage-gated calcium channel regulation of cardiac muscle cell action potential regulation of heart ... | anchoring junction; cytoplasm; cytosol; filopodium; glutamatergic synapse; mitochondrion; nucleus; podosome; postsynapse; presynapse; sarcoplasmic reticulum membrane; Z disc | mitogen-activated protein kinase kinase binding nitric-oxide synthase binding PDZ domain binding protease binding signaling adaptor activity | Rattus norvegicus | Cell junction Cell projection Coiled coil Phosphoprotein Reference proteome | MPSKTKYNLV | MPSKTKYNLVDDGHDLRIPLHNEDAFQHGISFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDGVKVILKKKKKKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSDGSGDPGRQLTGAERVSTATAEETDIDAVEVPLPGNDILEFSRGVTDLDAIGKDGGSHIDTTVSPHPQEPMLAASPRMLLPSSSSSKPPGLGTGTPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAA... | neuron projection regeneration neurotransmitter secretion positive regulation of peptidyl-cysteine S-nitrosylation postsynaptic actin cytoskeleton organization regulation of calcium ion transmembrane transport via high voltage-gated calcium channel regulation of cardiac muscle cell action potential regulation of heart ... |
chromatin organization DNA integration establishment of integrated proviral latency mitotic nuclear membrane reassembly negative regulation of cGAS/STING signaling pathway negative regulation of innate immune response negative regulation of protein ADP-ribosylation negative regulation of type I interferon production ne... | chromatin; condensed chromosome; cytoplasm; cytosol; nuclear envelope; nucleoplasm; nucleus | DNA binding double-stranded DNA binding identical protein binding protein homodimerization activity | Mus musculus | Acetylation Chromosome Cytoplasm DNA-binding Nucleus Phosphoprotein Reference proteome | MTTSQKHRDF | MTTSQKHRDFVAEPMGEKPVGSLAGIGDVLSKRLEERGFDKAYVVLGQFLVLKKDEDLFREWLKDTCGANAKQSRDCFGCLREWCDAFL | chromatin organization DNA integration establishment of integrated proviral latency mitotic nuclear membrane reassembly negative regulation of cGAS/STING signaling pathway negative regulation of innate immune response negative regulation of protein ADP-ribosylation negative regulation of type I interferon production ne... |
organelle localization positive regulation of stress-activated protein kinase signaling cascade protein autoubiquitination ubiquitin-dependent protein catabolic process | cytoplasm; cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; endosome; intracellular membrane-bounded organelle; late endosome membrane; lysosomal membrane; nuclear inner membrane; nucleoplasm | JUN kinase binding metal ion binding ubiquitin protein ligase activity ubiquitin-protein transferase activity | Mus musculus | Alternative splicing Endoplasmic reticulum Endosome Glycoprotein Lysosome Membrane Metal-binding Nucleus Reference proteome Signal Transferase Transmembrane Transmembrane helix Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger | MLLSIGMLML | MLLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFEDLPARFGYRLPAEGLKGFLINSKPENACEPIVPPPLKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIDTLKKIDIPSVFIGESSANSLKDEFTYEKGGHIILVPELSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRNRRNRLRKDQLKKLPVHKFKKGDEYDVCAICLEEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKVVPSQGDSDSDTDSSQEENQVSEHTPLLPPSASART... | organelle localization positive regulation of stress-activated protein kinase signaling cascade protein autoubiquitination ubiquitin-dependent protein catabolic process cytoplasm; cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; endosome; intracellular membrane-bounded organelle; late endosome membrane; ... |
DNA-templated transcription granulocyte differentiation negative regulation of cell population proliferation negative regulation of DNA-templated transcription negative regulation of glycolytic process negative regulation of transcription by RNA polymerase II positive regulation of proteasomal ubiquitin-dependent prote... | Golgi membrane; nucleolus; nucleoplasm; nucleus | chromatin binding metal ion binding transcription corepressor activity | Mus musculus | Alternative splicing Coiled coil Differentiation Golgi apparatus Membrane Metal-binding Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Zinc Zinc-finger | MSQASTTTLE | MSQASTTTLESGALLSGPRGLQYGSPAHRKEKAAAMPDSPAEVKTQPRSTPPSMPPPPPTSSQGATRPPSFTPHTHGEDGPATSLPHGRFHGCLKWSMVCLLMNGSSHSPTAIHGAPSTPNGFSNGPATSSTASLSTQHLPPACGARQLSKLKRFLTTLQQFGSDISPEIGERVRTLVLGLVNSTLTIEEFHAKLQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQTPAQYLAQHEQLLLDASATSPVDSSELLLEVNENGKRRTPDRTKENGSDRDPLHPDHLSKRSCTLSPAQRCSPSNGLPHPTPPPPPHYR... | DNA-templated transcription granulocyte differentiation negative regulation of cell population proliferation negative regulation of DNA-templated transcription negative regulation of glycolytic process negative regulation of transcription by RNA polymerase II positive regulation of proteasomal ubiquitin-dependent prote... |
bradykinin catabolic process negative regulation of programmed cell death proteolysis | cytoplasm; cytosol | aminopeptidase activity manganese ion binding metalloaminopeptidase activity protein homodimerization activity | Rattus norvegicus | Acetylation Aminopeptidase Cytoplasm Direct protein sequencing Hydrolase Manganese Metal-binding Metalloprotease Protease Reference proteome | MAPKVTSELL | MAPKVTSELLRQLRQAMRNSECVAEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSAGTAIITEEHAAMWTDGRYFLQAAKQMDNNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVDPLIIPTDYWKKMAKVLRSAGHHLVPVKENLVDKIWTDRPERPCKPLLTLGLDYTGISWKEKVADLRLKMAERSIVWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLERIMLFIDGDRIDAPGVKQHLLLDLGLEAEYKIQVLPYKSILSELKTLCADLSPREKVWVSDKASYAVSEAIPKDHRCCMPYTPICIAKA... | bradykinin catabolic process negative regulation of programmed cell death proteolysis cytoplasm; cytosol aminopeptidase activity manganese ion binding metalloaminopeptidase activity protein homodimerization activity Rattus norvegicus Acetylation Aminopeptidase Cytoplasm Direct protein sequencing Hydrolase Manganese Met... |
mitochondrial transport negative regulation of transcription by RNA polymerase II sensory perception of sound thyroid hormone metabolic process thyroid hormone transport | cytoplasm; cytosol; mitochondrion; nucleus | hormone binding NADP binding protein homodimerization activity thiomorpholine-carboxylate dehydrogenase activity thyroid hormone binding transcription corepressor activity | Mus musculus | 3D-structure Cytoplasm Direct protein sequencing NAD NADP Oxidoreductase Reference proteome | MKRAPAFLSA | MKRAPAFLSAEEVQDHLRSSSLLIPPLEAALANFSKGPDGGVMQPVRTVVPVAKHRGFLGVMPAYSAAEDALTTKLVTFYEGHSNTAVPSHQASVLLFDPSNGSLLAVMDGNVITAKRTAAVSAIATKLLKPPGSDVLCILGAGVQAYSHYEIFTEQFSFKEVRMWNRTRENAEKFASTVQGDVRVCSSVQEAVTGADVIITVTMATEPILFGEWVKPGAHINAVGASRPDWRELDDELMRQAVLYVDSREAALKESGDVLLSGADIFAELGEVISGAKPAHCEKTTVFKSLGMAVEDLVAAKLVYDSWSSGK | mitochondrial transport negative regulation of transcription by RNA polymerase II sensory perception of sound thyroid hormone metabolic process thyroid hormone transport cytoplasm; cytosol; mitochondrion; nucleus hormone binding NADP binding protein homodimerization activity thiomorpholine-carboxylate dehydrogenase act... |
camera-type eye photoreceptor cell differentiation glomerular parietal epithelial cell differentiation photoreceptor cell maintenance podocyte differentiation positive regulation of nephron tubule epithelial cell differentiation retina layer formation retina morphogenesis in camera-type eye | apical plasma membrane; brush border; cell projection; cell surface; cilium; endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment; extracellular exosome; extracellular space; microvillus; microvillus membrane; photoreceptor outer segment; photoreceptor outer segment membrane; plasma membrane; pro... | actinin binding cadherin binding cholesterol binding | Mus musculus | Acetylation Alternative splicing Cell membrane Cell projection Cilium Endoplasmic reticulum Glycoprotein Membrane Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix | MALVFSALLL | MALVFSALLLLGLCGKISSEGQPAFHNTPGAMNYELPTTKYETQDTFNAGIVGPLYKMVHIFLSVVQPNDFPLDLIKKLIQNKKFDISVDSKEPEIIVLALKIALYEIGVLICAILGLLFIILMPLVGCFFCMCRCCNKCGGEMHQRQKQNAPCRRKCLGLSLLVICLLMSLGIIYGFVANQQTRTRIKGTQKLAKSNFRDFQTLLTETPKQIDYVVEQYTNTKNKAFSDLDGIGSVLGGRIKDQLKPKVTPVLEEIKAMATAIKQTKDALQNMSSSLKSLQDAATQLNTNLSSVRNSIENSLSSSDCTSDPASKICDSI... | camera-type eye photoreceptor cell differentiation glomerular parietal epithelial cell differentiation photoreceptor cell maintenance podocyte differentiation positive regulation of nephron tubule epithelial cell differentiation retina layer formation retina morphogenesis in camera-type eye apical plasma membrane; brus... |
negative regulation of TOR signaling positive regulation of dendritic spine development positive regulation of telomere capping positive regulation of telomere maintenance via telomerase protein autophosphorylation Ras protein signal transduction regulation of translation stress-induced premature senescence | cytoplasm; cytosol; nucleoplasm; nucleus; protein-containing complex; septin cytoskeleton | ATP binding calcium-dependent protein serine/threonine kinase activity calmodulin binding calmodulin-dependent protein kinase activity mitogen-activated protein kinase binding p53 binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Mus musculus | Alternative splicing ATP-binding Coiled coil Cytoplasm Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase Tumor suppressor | MSEDSDMEKA | MSEDSDMEKAIKETSILEEYSINWTQKLGAGISGPVRVCVKKSTQERFALKILLDRPKARNEVRLHMMCATHPNIVQIIEVFANSVQFPHESSPRARLLIVMEMMEGGELFHRISQHRHFTEKQASQVTKQIALALQHCHLLNIAHRDLKPENLLFKDNSLDAPVKLCDFGFAKVDQGDLMTPQFTPYYVAPQVLEAQRRHQKEKSGIIPTSPTPYTYNKSCDLWSLGVIIYVMLCGYPPFYSKHHSRTIPKDMRKKIMTGSFEFPEEEWSQISEMAKDVVRKLLKVKPEERLTIEGVLDHPWLNSTEALDNVLPSAQLM... | negative regulation of TOR signaling positive regulation of dendritic spine development positive regulation of telomere capping positive regulation of telomere maintenance via telomerase protein autophosphorylation Ras protein signal transduction regulation of translation stress-induced premature senescence cytoplasm; ... |
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