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32,916,377
Biophys Chem
Silico analysis of interaction between full-length SARS-CoV2 S protein with human Ace2 receptor: Modelling, docking, MD simulation.
Many key residues, which mediate the interaction between SARS-CoV2 spike glycoprotein (S protein) and human ACE2 receptor, have been reviewed using the SARS-CoV2 S spike protein with human ACE2 complex. The initial SARS-CoV2 S protein and ACE2 protein complex structure is formed by RBD structure of SARS-CoV2 S protein ...
ace2;md;mm-pbsa;sars-cov2;spike protein
Journal Article
Rui, Li;Haonan, Li;Wanyi, Chen
10.1016/j.bpc.2020.106472
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Silico analysis of interaction between full-length SARS-CoV2 S protein with human Ace2 receptor: Modelling, docking, MD simulation. [Abstract]: Many key residues, which mediate the interaction between SARS-CoV2 spike glycoprotein (S protein) and human ACE2 receptor, have been reviewed using the SARS-CoV2 S spi...
32,410,206
Int J Clin Pharm
Clinical characteristics and drug therapies in patients with the common-type coronavirus disease 2019 in Hunan, China.
Background Clinical characteristics of patients with the coronavirus disease 2019 (COVID-19) may present differently within and outside the epicenter of Wuhan, China. More clinical investigations are needed. Objective The study was aimed to describe the clinical characteristics, laboratory parameters, and therapeutic m...
covid-19;clinical characteristics;infection;pharmacotherapy
Journal Article;Multicenter Study
Huang, Qiong;Deng, Xuanyu;Li, Yongzhong;Sun, Xuexiong;Chen, Qiong;Xie, Mingxuan;Liu, Shao;Qu, Hui;Liu, Shouxian;Wang, Ling;He, Gefei;Gong, Zhicheng
10.1007/s11096-020-01031-2
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical characteristics and drug therapies in patients with the common-type coronavirus disease 2019 in Hunan, China. [Abstract]: Background Clinical characteristics of patients with the coronavirus disease 2019 (COVID-19) may present differently within and outside the epicenter of Wuhan, China. More clinical...
32,816,307
Int J Gynaecol Obstet
Clinical characteristics, prognostic factors, and maternal and neonatal outcomes of SARS-CoV-2 infection among hospitalized pregnant women: A systematic review.
BACKGROUND: Pregnant women represent a potentially high-risk population in the COVID-19 pandemic. OBJECTIVE: To summarize clinical characteristics and outcomes among pregnant women hospitalized with COVID-19. SEARCH STRATEGY: Relevant databases were searched up until May 29, 2020. SELECTION CRITERIA: Case series/report...
covid-19;intrauterine fetal demise;maternal morbidity;maternal mortality;miscarriage;neonatal morbidity;neonatal mortality;preterm birth
Journal Article;Systematic Review
Turan, Ozlem;Hakim, Amir;Dashraath, Pradip;Jeslyn, Wong Jing Lin;Wright, Alison;Abdul-Kadir, Rezan
10.1002/ijgo.13329
[ 1, 1, 0, 0, 1, 0, 0 ]
[Title]: Clinical characteristics, prognostic factors, and maternal and neonatal outcomes of SARS-CoV-2 infection among hospitalized pregnant women: A systematic review. [Abstract]: BACKGROUND: Pregnant women represent a potentially high-risk population in the COVID-19 pandemic. OBJECTIVE: To summarize clinical charact...
32,600,101
Otolaryngol Head Neck Surg
Misconceptions About Negative Pressure Rooms and Their Impact Aboard USNS Comfort in New York City.
The outbreak of novel coronavirus disease 2019 (COVID-19) has had a momentous impact on the field of otolaryngology due to the high number of aerosol-generating procedures involving the upper aerodigestive tract. These procedures bear significant risk to the provider and clinical environment due to the possibility of v...
covid-19;sars cov-2;aerosol-generating procedure;air changes per hour;air handling;environmental control;environmental safety;high-risk aerosol;industrial hygiene;negative pressure room;otolaryngology;respiratory protection
Journal Article
Hill, Christopher J;Capra, Gregory G;McDonald, Thomas P;Santiago, Gabriel F;Radabaugh, J Paul
10.1177/0194599820938016
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Misconceptions About Negative Pressure Rooms and Their Impact Aboard USNS Comfort in New York City. [Abstract]: The outbreak of novel coronavirus disease 2019 (COVID-19) has had a momentous impact on the field of otolaryngology due to the high number of aerosol-generating procedures involving the upper aerodig...
32,308,988
Adv Simul (Lond)
The use of simulation to prepare and improve responses to infectious disease outbreaks like COVID-19: practical tips and resources from Norway, Denmark, and the UK.
In this paper, we describe the potential of simulation to improve hospital responses to the COVID-19 crisis. We provide tools which can be used to analyse the current needs of the situation, explain how simulation can help to improve responses to the crisis, what the key issues are with integrating simulation into orga...
Journal Article
Dieckmann, Peter;Torgeirsen, Kjetil;Qvindesland, Sigrun Anna;Thomas, Libby;Bushell, Verity;Langli Ersdal, Hege
10.1186/s41077-020-00121-5
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The use of simulation to prepare and improve responses to infectious disease outbreaks like COVID-19: practical tips and resources from Norway, Denmark, and the UK. [Abstract]: In this paper, we describe the potential of simulation to improve hospital responses to the COVID-19 crisis. We provide tools which ca...
32,965,736
FASEB J
SARS-CoV-2 and the possible connection to ERs, ACE2, and RAGE: Focus on susceptibility factors.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has provoked major stresses on the health-care systems of several countries, and caused the death of more than a quarter of a million people globally, mainly in the elderly population with preexisting pathologies. Previous studies with coronaviru...
ace2;covid-19;rage;estrogen
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't;Review
Stilhano, Roberta Sessa;Costa, Angelica Jardim;Nishino, Michelle Sayuri;Shams, Shahin;Bartolomeo, Cynthia Silva;Breithaupt-Faloppa, Ana Cristina;Silva, Eduardo Alexandre;Ramirez, Ana Lopez;Prado, Carla Maximo;Ureshino, Rodrigo Portes
10.1096/fj.202001394RR
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: SARS-CoV-2 and the possible connection to ERs, ACE2, and RAGE: Focus on susceptibility factors. [Abstract]: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has provoked major stresses on the health-care systems of several countries, and caused the death of more than a quarter of a mil...
33,062,950
ACS Pharmacol Transl Sci
Potential Therapeutic Agents and Associated Bioassay Data for COVID-19 and Related Human Coronavirus Infections.
The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, has led to several million confirmed cases and hundreds of thousands of deaths worldwide. To support the ongoing research and development of COVID-19 therapeutics, this report provides an overview of protein targets and corresponding potential drug cand...
Journal Article;Review
Zhou, Qiongqiong Angela;Kato-Weinstein, Junko;Li, Yingzhu;Deng, Yi;Granet, Roger;Garner, Linda;Liu, Cynthia;Polshakov, Dmitrii;Gessner, Chris;Watkins, Steven
10.1021/acsptsci.0c00074
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Potential Therapeutic Agents and Associated Bioassay Data for COVID-19 and Related Human Coronavirus Infections. [Abstract]: The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, has led to several million confirmed cases and hundreds of thousands of deaths worldwide. To support the ongoing resear...
32,764,857
J Orthop
Triaging Spine Surgery and Treatment during the COVID-19 Pandemic.
Objective: To utilize evidence-based medicine to help determine guidelines for spinal surgery during the Covid-19 era. Methods: A literature review was performed of peer-reviewed articles focused on indications for common procedures in spine surgery. Based on these indications, we sub-categorized these procedures into ...
covid-19;coronavirus;infectious disease;pandemic;spinal surgery;spine
Journal Article;Review
Rizkalla, James M;Hotchkiss, William;Clavenna, Andrew;Dossett, Andrew;Syed, Ishaq Y
10.1016/j.jor.2020.06.015
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Triaging Spine Surgery and Treatment during the COVID-19 Pandemic. [Abstract]: Objective: To utilize evidence-based medicine to help determine guidelines for spinal surgery during the Covid-19 era. Methods: A literature review was performed of peer-reviewed articles focused on indications for common procedures...
32,607,499
Research (Wash D C)
Combating the Coronavirus Pandemic: Early Detection, Medical Treatment, and a Concerted Effort by the Global Community.
The World Health Organization (WHO) has declared the outbreak of 2019 novel coronavirus, known as 2019-nCoV, a pandemic, as the coronavirus has now infected over 2.6 million people globally and caused more than 185,000 fatalities as of April 23, 2020. Coronavirus disease 2019 (COVID-19) causes a respiratory illness wit...
Journal Article;Review
Luo, Zichao;Ang, Melgious Jin Yan;Chan, Siew Yin;Yi, Zhigao;Goh, Yi Yiing;Yan, Shuangqian;Tao, Jun;Liu, Kai;Li, Xiaosong;Zhang, Hongjie;Huang, Wei;Liu, Xiaogang
10.34133/2020/6925296
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Combating the Coronavirus Pandemic: Early Detection, Medical Treatment, and a Concerted Effort by the Global Community. [Abstract]: The World Health Organization (WHO) has declared the outbreak of 2019 novel coronavirus, known as 2019-nCoV, a pandemic, as the coronavirus has now infected over 2.6 million peopl...
32,919,977
Am J Pathol
Immunopathology of Hyperinflammation in COVID-19.
The rapid spread of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), has resulted in an unprecedented public health crisis worldwide. Recent studies indicate that a hyperinflammatory syndrome induced by SARS-CoV-2 contributes to disease severity and mortality ...
Journal Article;Review
Gustine, Joshua N;Jones, Dennis
10.1016/j.ajpath.2020.08.009
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Immunopathology of Hyperinflammation in COVID-19. [Abstract]: The rapid spread of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), has resulted in an unprecedented public health crisis worldwide. Recent studies indicate that a hyperinflammatory syndro...
33,051,286
BMJ Glob Health
Thinking differently: lessons learned by international public health specialists while supporting the Integrated Disease Surveillance and Response system in Pakistan.
Internationally supported activities to build public health capacity and improve compliance with International Health Regulations (2005) so that countries are better able to 'prevent, protect against, control and provide a public health response to the international spread of disease' have had a positive impact in rece...
diseases;disorders;health systems;infections;injuries;public health
Journal Article
Wilson, Anne;Cartwright, Christopher
10.1136/bmjgh-2020-003593
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Thinking differently: lessons learned by international public health specialists while supporting the Integrated Disease Surveillance and Response system in Pakistan. [Abstract]: Internationally supported activities to build public health capacity and improve compliance with International Health Regulations (2...
32,538,594
Am Fam Physician
Acute Respiratory Distress Syndrome: Diagnosis and Management.
Acute respiratory distress syndrome (ARDS) is noncardiogenic pulmonary edema that manifests as rapidly progressive dyspnea, tachypnea, and hypoxemia. Diagnostic criteria include onset within one week of a known insult or new or worsening respiratory symptoms, profound hypoxemia, bilateral pulmonary opacities on radiogr...
Journal Article;Review
Saguil, Aaron;Fargo, Matthew V
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Acute Respiratory Distress Syndrome: Diagnosis and Management. [Abstract]: Acute respiratory distress syndrome (ARDS) is noncardiogenic pulmonary edema that manifests as rapidly progressive dyspnea, tachypnea, and hypoxemia. Diagnostic criteria include onset within one week of a known insult or new or worsenin...
33,012,602
Vaccine
Ensemble forecast modeling for the design of COVID-19 vaccine efficacy trials.
To rapidly evaluate the safety and efficacy of COVID-19 vaccine candidates, prioritizing vaccine trial sites in areas with high expected disease incidence can speed endpoint accrual and shorten trial duration. Mathematical and statistical forecast models can inform the process of site selection, integrating available d...
efficacy trial;ensemble modeling;forecast model;trial planning
Journal Article;Research Support, N.I.H., Extramural
Dean, Natalie E;Pastore Y Piontti, Ana;Madewell, Zachary J;Cummings, Derek A T;Hitchings, Matthew D T;Joshi, Keya;Kahn, Rebecca;Vespignani, Alessandro;Halloran, M Elizabeth;Longini, Ira M Jr
10.1016/j.vaccine.2020.09.031
[ 1, 0, 0, 0, 0, 1, 0 ]
[Title]: Ensemble forecast modeling for the design of COVID-19 vaccine efficacy trials. [Abstract]: To rapidly evaluate the safety and efficacy of COVID-19 vaccine candidates, prioritizing vaccine trial sites in areas with high expected disease incidence can speed endpoint accrual and shorten trial duration. Mathematic...
32,838,206
Mayo Clin Proc Innov Qual Outcomes
A Narrative Review of Emerging Therapeutics for COVID-19.
The novel severe acute respiratory syndrome coronavirus 2, the causal agent of coronavirus disease 2019 (COVID-19), quickly spread around the world, resulting in the most aggressive pandemic experienced in more than 100 years. Research on targeted therapies and vaccines has been initiated on an unprecedented scale and ...
covid-19, coronavirus disease 2019;cpt, convalescent plasma therapy;cq, chloroquine;ec50, half-maximal effective concentration;hcq, hydroxychloroquine;icu, intensive care unit;il-6, interleukin 6;jak, janus kinase;lpv/rtv, lopinavir/ritonavir;mers, middle east respiratory syndrome;rct, randomized controlled trial;sars,...
Journal Article;Review
Willis, Van C;Arriaga, Yull;Weeraratne, Dilhan;Reyes, Fredy;Jackson, Gretchen P
10.1016/j.mayocpiqo.2020.07.004
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: A Narrative Review of Emerging Therapeutics for COVID-19. [Abstract]: The novel severe acute respiratory syndrome coronavirus 2, the causal agent of coronavirus disease 2019 (COVID-19), quickly spread around the world, resulting in the most aggressive pandemic experienced in more than 100 years. Research on ta...
32,627,963
Thorac Cancer
Surgical care of thoracic malignancies during the COVID-19 pandemic in Mexico: An expert consensus guideline from the Sociedad Mexicana de Oncologia (SMeO) and the Sociedad Mexicana de Cirujanos Toracicos Generales (SMCTG).
To date, the impact, timeline and duration of COVID-19 pandemic remains unknown and more than ever it is necessary to provide safe pathways for cancer patients. Multiple triage systems for nonemergent surgical procedures have been published, but potentially curative cancer procedures are essential surgery rather than e...
covid-19;lung cancer;surgical oncology;thoracic oncology;thoracic surgery
Journal Article;Research Support, Non-U.S. Gov't
Corona-Cruz, Jose;Alba, Enrique Guzman-de;Iniguez-Garcia, Marco;Lopez-Saucedo, Raul;Olivares-Torres, Carlos;Rodriguez-Cid, Jeronimo;Salazar-Otaola, Gustavo;Martinez-Said, Hector;Flores, Raja M;Arrieta, Oscar
10.1111/1759-7714.13546
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Surgical care of thoracic malignancies during the COVID-19 pandemic in Mexico: An expert consensus guideline from the Sociedad Mexicana de Oncologia (SMeO) and the Sociedad Mexicana de Cirujanos Toracicos Generales (SMCTG). [Abstract]: To date, the impact, timeline and duration of COVID-19 pandemic remains unk...
32,942,560
Int J Environ Res Public Health
A Call for Action to Safely Deliver Oral Health Care during and Post COVID-19 Pandemic.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak started just a couple of months ago and it grew rapidly causing several deaths and morbidities. The mechanism behind the transmission of the virus is still not completely understood despite a multitude of new specific manuscripts being published ...
angiotensin ii;coronavirus;mouth;pandemics;professional practice;quarantine
Journal Article
Farronato, Marco;Tadakamadla, Santosh K;Ali Quadri, Mir Faeq;Acharya, Shashidhar;Tadakamadla, Jyothi;Love, Robert M;Jamal, Mohamed;Mulder, Riaan;Maspero, Cinzia;Farronato, Davide;Ivanov, Alexander;Neefs, Dirk;Cagetti, Maria Grazia;de Vito, Danila;Gupta, Rishi J;Connelly, Stephen Thaddeus;Tartaglia, Gianluca M
10.3390/ijerph17186704
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A Call for Action to Safely Deliver Oral Health Care during and Post COVID-19 Pandemic. [Abstract]: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak started just a couple of months ago and it grew rapidly causing several deaths and morbidities. The mechanism behind the transmission of ...
32,557,820
Int J Health Plann Manage
Coronavirus Disease 2019 (COVID-19): Potential implications for weak health systems and conflict zones in the Middle East and North Africa region.
This short communication recognizes the underbelly of weak and conflict-prone health systems in the Middle East and North Africa region in the wake of COVID-19 pandemic. The communication highlights how the lack of basic resources, absence of a well-functioning health system and the dearth of well-coordinated communica...
covid-19;covid-19 implications;who mena region;weak health systems;conflict zones
Journal Article
Da'ar, Omar B;Haji, Mohamed;Jradi, Hoda
10.1002/hpm.2982
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Coronavirus Disease 2019 (COVID-19): Potential implications for weak health systems and conflict zones in the Middle East and North Africa region. [Abstract]: This short communication recognizes the underbelly of weak and conflict-prone health systems in the Middle East and North Africa region in the wake of C...
32,791,493
J Med Internet Res
App-Based Tracking of Self-Reported COVID-19 Symptoms: Analysis of Questionnaire Data.
BACKGROUND: COVID-19 is an infectious disease characterized by various clinical presentations. Knowledge of possible symptoms and their distribution allows for the early identification of infected patients. OBJECTIVE: To determine the distribution pattern of COVID-19 symptoms as well as possible unreported symptoms, we...
covid-19;app;digital tool;distribution;screening;self-reporting;surveillance;symptom;tracking
Journal Article;Research Support, Non-U.S. Gov't
Zens, Martin;Brammertz, Arne;Herpich, Juliane;Sudkamp, Norbert;Hinterseer, Martin
10.2196/21956
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: App-Based Tracking of Self-Reported COVID-19 Symptoms: Analysis of Questionnaire Data. [Abstract]: BACKGROUND: COVID-19 is an infectious disease characterized by various clinical presentations. Knowledge of possible symptoms and their distribution allows for the early identification of infected patients. OBJEC...
32,758,904
Med Hypotheses
N-acetycysteine: A potential therapeutic agent in COVID-19 infection.
COVID-19 is an overwhelming pandemic which has shattered the whole world. Lung injury being the main clinical manifestation, it is likely to cause COPD (chronic obstructive pulmonary disease) and ARDS (acute respiratory distress syndrome). The possible cause behind this might be redox imbalance due to viral infection. ...
covid-19;glutathione;n-acetylcysteine;oxidative stress
Letter
Jaiswal, N;Bhatnagar, M;Shah, H
10.1016/j.mehy.2020.110133
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: N-acetycysteine: A potential therapeutic agent in COVID-19 infection. [Abstract]: COVID-19 is an overwhelming pandemic which has shattered the whole world. Lung injury being the main clinical manifestation, it is likely to cause COPD (chronic obstructive pulmonary disease) and ARDS (acute respiratory distress ...
32,466,289
Pathogens
Cellular Metabolic Profiling of CrFK Cells Infected with Feline Infectious Peritonitis Virus Using Phenotype Microarrays.
Feline infectious peritonitis (FIP) is a fatal feline immune-mediated disease caused by feline infectious peritonitis virus (FIPV). Little is known about the biological pathways associated in FIP pathogenesis. This is the first study aiming to determine the phenotypic characteristics on the cellular level in relation t...
crfk cells;cellular metabolism;feline infectious peritonitis virus;glutamine;metabolic profiling;phenotype microarray
Journal Article
Ng, Shing Wei;Selvarajah, Gayathri Thevi;Cheah, Yoke Kqueen;Mustaffa Kamal, Farina;Omar, Abdul Rahman
10.3390/pathogens9050412
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Cellular Metabolic Profiling of CrFK Cells Infected with Feline Infectious Peritonitis Virus Using Phenotype Microarrays. [Abstract]: Feline infectious peritonitis (FIP) is a fatal feline immune-mediated disease caused by feline infectious peritonitis virus (FIPV). Little is known about the biological pathways...
32,951,890
J Pediatr Surg
Allocation of resources and development of guidelines for extracorporeal membrane oxygenation (ECMO): Experience from a pediatric center in the epicenter of the COVID-19 pandemic.
The rapid spread of coronavirus disease 2019 (COVID-19) has exceeded the standard capacity of many hospital systems and led to an unprecedented scarcity of resources, including the already limited resource of extracorporeal membrane oxygenation (ECMO). With the large amount of critically ill patients and the highly con...
acute respiratory distress syndrome (ards);covid-19;extracorporeal membrane oxygenation (ecmo);pandemic;sars-cov-2
Journal Article;Review
Gerall, Claire;Cheung, Eva W;Klein-Cloud, Rafael;Kreines, Erica;Brewer, Michael;Middlesworth, William
10.1016/j.jpedsurg.2020.08.015
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Allocation of resources and development of guidelines for extracorporeal membrane oxygenation (ECMO): Experience from a pediatric center in the epicenter of the COVID-19 pandemic. [Abstract]: The rapid spread of coronavirus disease 2019 (COVID-19) has exceeded the standard capacity of many hospital systems and...
32,749,808
Ned Tijdschr Geneeskd
[Hydroxychloroquine and chloroquine for COVID-19: no evidence of effectiveness].
On 3 March 2020, the document 'Drug treatment options for patients with COVID-19 (infections with SARS-CoV-2)' was published on the website of the Dutch Working Party on Antibiotic Policy (StichtingWerkgroepAntibioticabeleid, SWAB). Based on a 7-step analysis of the literature, hydroxychloroquine (HCQ) and chloroquine ...
Journal Article
Vollaard, A;Gieling, E M;van der Linden, P D;Sinha, B;de Boer, M G J
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: [Hydroxychloroquine and chloroquine for COVID-19: no evidence of effectiveness]. [Abstract]: On 3 March 2020, the document 'Drug treatment options for patients with COVID-19 (infections with SARS-CoV-2)' was published on the website of the Dutch Working Party on Antibiotic Policy (StichtingWerkgroepAntibiotica...
32,981,508
Rev Recent Clin Trials
COVID-19 and Pneumolysis Simulating Extreme High-altitude Exposure with Altered Oxygen Transport Physiology; Multiple Diseases, and Scarce Need of Ventilators: Andean Condor's-eye-view.
BACKGROUND: Critical hypoxia in this COVID-19 pandemic results in high mortality and economic loss worldwide. Initially, this disease' pathophysiology was poorly understood and interpreted as a SARS (Severe Acute Respiratory Syndrome) pneumonia. The severe atypical lung CAT scan images alerted all countries, including ...
epo;hape;open circuit earth space suits.;polyerythrocythemia;sars-cov-2;tolerance to hypoxia
Comparative Study;Journal Article;Review
Zubieta-Calleja, Gustavo R;Zubieta-DeUrioste, Natalia;Venkatesh, Thuppil;Das, Kusal;Soliz, Jorge
10.2174/1574887115666200925141108
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 and Pneumolysis Simulating Extreme High-altitude Exposure with Altered Oxygen Transport Physiology; Multiple Diseases, and Scarce Need of Ventilators: Andean Condor's-eye-view. [Abstract]: BACKGROUND: Critical hypoxia in this COVID-19 pandemic results in high mortality and economic loss worldwide. Ini...
32,852,082
Aliment Pharmacol Ther
Systematic review with meta-analysis: SARS-CoV-2 stool testing and the potential for faecal-oral transmission.
BACKGROUND: Since the start of the COVID-19 pandemic, there have been many scientific reports regarding gastrointestinal manifestations. Several reports indicate the possibility of viral shedding via faeces and the possibility of faecal-oral transmission. AIMS: To critically assess the clinical relevance of testing sto...
covid-19;coronavirus;sars-cov-2;anal swab;faecal-oral transmission;stool test
Journal Article;Meta-Analysis;Systematic Review
van Doorn, Amarylle S;Meijer, Berrie;Frampton, Chris M A;Barclay, Murray L;de Boer, Nanne K H
10.1111/apt.16036
[ 0, 1, 0, 0, 1, 0, 0 ]
[Title]: Systematic review with meta-analysis: SARS-CoV-2 stool testing and the potential for faecal-oral transmission. [Abstract]: BACKGROUND: Since the start of the COVID-19 pandemic, there have been many scientific reports regarding gastrointestinal manifestations. Several reports indicate the possibility of viral s...
32,337,139
Cureus
Searching an Effective Therapy for the Coronavirus Pandemic: Do We See Light at the End of the Tunnel?
Coronavirus disease 2019 (COVID-19) is an emerging infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). First reported at the end of December 2019 as a cause for clusters of pneumonia cases in Wuhan city in China, the rapid spread of this condition was declared a pandemic on March ...
azithromycin;coronavirus disease;hydroxychloroquine;sars-cov-2 (severe acute respiratory syndrome coronavirus -2)
Journal Article;Review
Sharma, Munish;Surani, Salim
10.7759/cureus.7415
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Searching an Effective Therapy for the Coronavirus Pandemic: Do We See Light at the End of the Tunnel? [Abstract]: Coronavirus disease 2019 (COVID-19) is an emerging infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). First reported at the end of December 2019 as a cause ...
32,476,778
J Orthop
Orthopaedic Walk-In Clinics: A model to lessen the burden on Emergency Departments during the COVID-19 pandemic.
Objective: Operating duties for orthopaedic surgeons decreased during the COVID-19 pandemic, while Emergency Department (ED) cases surged. Orthopaedic Walk-In Clinics (OWICs) were implemented to manage urgent musculoskeletal cases. Methods: OWICs, organized in three days, were staffed by one orthopaedic surgeon, one tr...
Journal Article
MacKechnie, Madeline C;Nadeau, Molly;Deering, Ericka;Thaller, John;MacKechnie, Michael A
10.1016/j.jor.2020.05.014
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Orthopaedic Walk-In Clinics: A model to lessen the burden on Emergency Departments during the COVID-19 pandemic. [Abstract]: Objective: Operating duties for orthopaedic surgeons decreased during the COVID-19 pandemic, while Emergency Department (ED) cases surged. Orthopaedic Walk-In Clinics (OWICs) were implem...
32,640,417
Diabetes Metab Syndr
Neuroinvasive potential of a primary respiratory pathogen SARS- CoV2: Summarizing the evidences.
BACKROUND AND AIMS: After the emergence of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in the last two decades, the world is facing its new challenge in SARS-CoV-2 pandemic with unfathomable global responses. The characteristic clinical symptoms f...
ace2;cns;covid-19;coronavirus;neurological disorders;pns;phylogenetic perspective;sars-cov2
Journal Article;Review
Lahiri, Durjoy;Mondal, Ritwick;Deb, Shramana;Bandyopadhyay, Deebya;Shome, Gourav;Sarkar, Sukanya;Biswas, Subhas C
10.1016/j.dsx.2020.06.062
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Neuroinvasive potential of a primary respiratory pathogen SARS- CoV2: Summarizing the evidences. [Abstract]: BACKROUND AND AIMS: After the emergence of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in the last two decades, the world is faci...
32,844,144
TH Open
COVID-19 and Cold Agglutinin Hemolytic Anemia.
Novel coronavirus disease 2019 (COVID-19) has spread throughout the world and has infected close to 4 million people. It commonly presents with fever, cough, and fatigue. Due to the high inflammatory response, it is suggested that the coagulation cascade is enhanced causing thrombotic events for many patients. We descr...
autoantibodies;thrombosis;viral infection
Case Reports
Maslov, Diana V;Simenson, Victoria;Jain, Suma;Badari, Ambuga
10.1055/s-0040-1715791
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: COVID-19 and Cold Agglutinin Hemolytic Anemia. [Abstract]: Novel coronavirus disease 2019 (COVID-19) has spread throughout the world and has infected close to 4 million people. It commonly presents with fever, cough, and fatigue. Due to the high inflammatory response, it is suggested that the coagulation casca...
33,022,757
J Am Geriatr Soc
State Actions and Shortages of Personal Protective Equipment and Staff in U.S. Nursing Homes.
BACKGROUND: It is crucial that nursing homes have adequate personal protective equipment (PPE) and staff to protect residents and staff from COVID-19. Some states have taken actions to mitigate shortages of PPE and staffing in nursing homes, including creating dedicated long-term care (LTC) teams and supporting staffin...
covid-19;nursing homes;personal protective equipment;staffing
Journal Article
Gibson, Diane M;Greene, Jessica
10.1111/jgs.16883
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: State Actions and Shortages of Personal Protective Equipment and Staff in U.S. Nursing Homes. [Abstract]: BACKGROUND: It is crucial that nursing homes have adequate personal protective equipment (PPE) and staff to protect residents and staff from COVID-19. Some states have taken actions to mitigate shortages o...
32,525,600
FASEB J
Genetic gateways to COVID-19 infection: Implications for risk, severity, and outcomes.
The dynamics, such as transmission, spatial epidemiology, and clinical course of Coronavirus Disease-2019 (COVID-19) have emerged as the most intriguing features and remain incompletely understood. The genetic landscape of an individual in particular, and a population in general seems to play a pivotal role in shaping ...
ace;covid-19;hla;sars-cov-2;cytokine storm;genetics;immunity
Journal Article;Review
Debnath, Monojit;Banerjee, Moinak;Berk, Michael
10.1096/fj.202001115R
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Genetic gateways to COVID-19 infection: Implications for risk, severity, and outcomes. [Abstract]: The dynamics, such as transmission, spatial epidemiology, and clinical course of Coronavirus Disease-2019 (COVID-19) have emerged as the most intriguing features and remain incompletely understood. The genetic la...
33,020,340
Acta Med Indones
Prevention of Ventricular Arrhythmia and Sudden Cardiac Death in COVID-19 Patients.
Since the first case was reported at the end of 2019, COVID-19 has spread throughout the world and has become a pandemic. The high transmission rate of the virus has made it a threat to public health globally. Viral infections may trigger acute coronary syndromes, arrhythmias, and exacerbation of heart failure, due to ...
qt;arrhythmia;azithromycin;covid-19;hydroxychlorine
Journal Article;Review
Yamin, Muhammad;Demili, Amanda Ulfah
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Prevention of Ventricular Arrhythmia and Sudden Cardiac Death in COVID-19 Patients. [Abstract]: Since the first case was reported at the end of 2019, COVID-19 has spread throughout the world and has become a pandemic. The high transmission rate of the virus has made it a threat to public health globally. Viral...
32,172,672
Emerg Microbes Infect
A tug-of-war between severe acute respiratory syndrome coronavirus 2 and host antiviral defence: lessons from other pathogenic viruses.
World Health Organization has declared the ongoing outbreak of coronavirus disease 2019 (COVID-19) a Public Health Emergency of International Concern. The virus was named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by the International Committee on Taxonomy of Viruses. Human infection with SARS-CoV-2 l...
2019 novel coronavirus;covid-19;coronavirus;sars-cov;sars-cov-2;host antiviral response;type i interferon
Journal Article;Review
Fung, Sin-Yee;Yuen, Kit-San;Ye, Zi-Wei;Chan, Chi-Ping;Jin, Dong-Yan
10.1080/22221751.2020.1736644
[ 0, 0, 0, 1, 1, 0, 0 ]
[Title]: A tug-of-war between severe acute respiratory syndrome coronavirus 2 and host antiviral defence: lessons from other pathogenic viruses. [Abstract]: World Health Organization has declared the ongoing outbreak of coronavirus disease 2019 (COVID-19) a Public Health Emergency of International Concern. The virus wa...
33,040,233
Eur Arch Otorhinolaryngol
Delays in surgery for cholesteatoma due to COVID-19: is there an impact on rates of recidivism and major complications?
PURPOSE: To evaluate the relationship between the waiting time for surgery, and cholesteatoma recidivism rates and major complications. The secondary aims were to identify any other prognostic factors for cholesteatoma recidivism. METHODS: A retrospective single-centre study of 312 patients who underwent cholesteatoma ...
cholesteatoma;mastoid;recidivism;recurrence;time factors
Journal Article
Hussain, Mohammed Hassan;Mair, Manish;Mahmood, Sara;Sakagiannis, Georgios;Rojoa, Djamila M;Raheman, Firas J;Irvine, Esmee;Rea, Peter
10.1007/s00405-020-06416-7
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Delays in surgery for cholesteatoma due to COVID-19: is there an impact on rates of recidivism and major complications? [Abstract]: PURPOSE: To evaluate the relationship between the waiting time for surgery, and cholesteatoma recidivism rates and major complications. The secondary aims were to identify any oth...
32,901,582
Curr Protein Pept Sci
Fusion protein targeted antiviral peptides: fragment based drug design (FBDD) guided rational design of dipeptides against SARS-CoV-2.
Infectious diseases caused by viruses become a serious public health issue in the recent past, including current pandemic situation of COVID-19. Enveloped viruses are most commonly known to cause emerging and recurring infectious diseases. Viral and cell membrane fusion is the major key event in case of enveloped virus...
viral infections;antiviral peptides;enveloped viruses;fusion protein
Journal Article
Manna, Sounik;Chowdhury, Trinath;Baindara, Piyush;Mandal, Santi M
10.2174/1389203721666200908164641
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Fusion protein targeted antiviral peptides: fragment based drug design (FBDD) guided rational design of dipeptides against SARS-CoV-2. [Abstract]: Infectious diseases caused by viruses become a serious public health issue in the recent past, including current pandemic situation of COVID-19. Enveloped viruses a...
32,815,099
J Cell Commun Signal
Repurposing calcium channel blockers as antiviral drugs.
The current pandemic caused by the SARS-CoV-2 has claimed over a half a million lives within a very short span of time. A therapeutic drug which could prevent the entry and propagation of the virus is the need of the hour. Several lines of evidence collected from experimental studies older than three decades have point...
ccb;calcium channels;calcium homeostasis;sars;verapamil;virus
Journal Article
Jayaseelan, Vijayashree Priyadharsini;Paramasivam, Arumugam
10.1007/s12079-020-00579-y
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Repurposing calcium channel blockers as antiviral drugs. [Abstract]: The current pandemic caused by the SARS-CoV-2 has claimed over a half a million lives within a very short span of time. A therapeutic drug which could prevent the entry and propagation of the virus is the need of the hour. Several lines of ev...
32,909,495
Health Informatics J
Intermittent demand forecasting for medical consumables with short life cycle using a dynamic neural network during the COVID-19 epidemic.
Accurate demand forecasting is always critical to supply chain management. However, many uncertain factors in the market make this issue a huge challenge. Especially during the current COVID-19 outbreak, the shortage of certain types of medical consumables has become a global problem. The intermittent demand forecast o...
accuracy measurement;dynamic neural network;intermittent demand forecasting;optimized model selection;short life cycle
Journal Article;Research Support, Non-U.S. Gov't
Liu, Peipei
10.1177/1460458220954730
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Intermittent demand forecasting for medical consumables with short life cycle using a dynamic neural network during the COVID-19 epidemic. [Abstract]: Accurate demand forecasting is always critical to supply chain management. However, many uncertain factors in the market make this issue a huge challenge. Espec...
33,050,511
Viruses
Impact of Microbiota: A Paradigm for Evolving Herd Immunity against Viral Diseases.
Herd immunity is the most critical and essential prophylactic intervention that delivers protection against infectious diseases at both the individual and community level. This process of natural vaccination is immensely pertinent to the current context of a pandemic caused by severe acute respiratory syndrome coronavi...
ee;sars-cov-2;herd immunity;heterologous immunity;microbiome;nutrition
Journal Article;Research Support, Non-U.S. Gov't;Review
Shelly, Asha;Gupta, Priya;Ahuja, Rahul;Srichandan, Sudeepa;Meena, Jairam;Majumdar, Tanmay
10.3390/v12101150
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Impact of Microbiota: A Paradigm for Evolving Herd Immunity against Viral Diseases. [Abstract]: Herd immunity is the most critical and essential prophylactic intervention that delivers protection against infectious diseases at both the individual and community level. This process of natural vaccination is imme...
32,897,374
JAMA Netw Open
Comparison of Clinical Features of COVID-19 vs Seasonal Influenza A and B in US Children.
Importance: Compared with seasonal influenza, the clinical features and epidemiologic characteristics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus 2019 (COVID-19) in US children remain largely unknown. Objective: To describe the similarities and differences in clinical features betwee...
Journal Article;Comment
Song, Xiaoyan;Delaney, Meghan;Shah, Rahul K;Campos, Joseph M;Wessel, David L;DeBiasi, Roberta L
10.1001/jamanetworkopen.2020.20495
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Comparison of Clinical Features of COVID-19 vs Seasonal Influenza A and B in US Children. [Abstract]: Importance: Compared with seasonal influenza, the clinical features and epidemiologic characteristics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus 2019 (COVID-19) in US child...
33,028,347
Hum Resour Health
Maternal and newborn care during the COVID-19 pandemic in Kenya: re-contextualising the community midwifery model.
Peripartum deaths remain significantly high in low- and middle-income countries, including Kenya. The COVID-19 pandemic has disrupted essential services, which could lead to an increase in maternal and neonatal mortality and morbidity. Furthermore, the lockdowns, curfews, and increased risk for contracting COVID-19 may...
africa;covid-19;community interventions;community health;coronavirus;kenya;lmic;maternal;midwifery;neonatal;pandemic;pregnant women
Journal Article;Review
Kimani, Rachel Wangari;Maina, Rose;Shumba, Constance;Shaibu, Sheila
10.1186/s12960-020-00518-3
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Maternal and newborn care during the COVID-19 pandemic in Kenya: re-contextualising the community midwifery model. [Abstract]: Peripartum deaths remain significantly high in low- and middle-income countries, including Kenya. The COVID-19 pandemic has disrupted essential services, which could lead to an increas...
32,877,502
Blood
Direct activation of the alternative complement pathway by SARS-CoV-2 spike proteins is blocked by factor D inhibition.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious respiratory virus that can lead to venous/arterial thrombosis, stroke, renal failure, myocardial infarction, thrombocytopenia, and other end-organ damage. Animal models demonstrating end-organ protection in C3-deficient mice and evidenc...
Journal Article;Research Support, N.I.H., Extramural
Yu, Jia;Yuan, Xuan;Chen, Hang;Chaturvedi, Shruti;Braunstein, Evan M;Brodsky, Robert A
10.1182/blood.2020008248
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Direct activation of the alternative complement pathway by SARS-CoV-2 spike proteins is blocked by factor D inhibition. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious respiratory virus that can lead to venous/arterial thrombosis, stroke, renal failure, myocardia...
32,648,850
J Med Internet Res
Public Health in the Information Age: Recognizing the Infosphere as a Social Determinant of Health.
Since 2016, social media companies and news providers have come under pressure to tackle the spread of political mis- and disinformation (MDI) online. However, despite evidence that online health MDI (on the web, on social media, and within mobile apps) also has negative real-world effects, there has been a lack of com...
covid-19;disinformation;infodemic;infodemiology;information ethics;infosphere;misinformation;public health;social determinants of health
Journal Article
Morley, Jessica;Cowls, Josh;Taddeo, Mariarosaria;Floridi, Luciano
10.2196/19311
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Public Health in the Information Age: Recognizing the Infosphere as a Social Determinant of Health. [Abstract]: Since 2016, social media companies and news providers have come under pressure to tackle the spread of political mis- and disinformation (MDI) online. However, despite evidence that online health MDI...
32,377,677
Age Ageing
COVID-19 in older people: a rapid clinical review.
INTRODUCTION: the COVID-19 pandemic poses a high risk to older people. The aim of this article is to provide a rapid overview of the COVID-19 literature, with a specific focus on older adults. We frame our findings within an overview of the disease and have also evaluated the inclusion of older people within forthcomin...
covid-19;non-pharmaceutical interventions;older adults;pandemic;prognosis;virology
Journal Article;Review
Lithander, Fiona E;Neumann, Sandra;Tenison, Emma;Lloyd, Katherine;Welsh, Tomas J;Rodrigues, Jonathan C L;Higgins, Julian P T;Scourfield, Lily;Christensen, Hannah;Haunton, Victoria J;Henderson, Emily J
10.1093/ageing/afaa093
[ 1, 1, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 in older people: a rapid clinical review. [Abstract]: INTRODUCTION: the COVID-19 pandemic poses a high risk to older people. The aim of this article is to provide a rapid overview of the COVID-19 literature, with a specific focus on older adults. We frame our findings within an overview of the disease...
32,246,317
J Thromb Thrombolysis
Difference of coagulation features between severe pneumonia induced by SARS-CoV2 and non-SARS-CoV2.
Severe coronavirus disease 2019 (COVID-19) is commonly complicated with coagulopathy, the difference of coagulation features between severe pneumonia induced by SARS-CoV2 and non-SARS-CoV2 has not been analyzed. Coagulation results and clinical features of consecutive patients with severe pneumonia induced by SARS-CoV2...
coagulopathy;coronavirus disease 2019;d-dimer;severe pneumonia
Journal Article
Yin, Shiyu;Huang, Ming;Li, Dengju;Tang, Ning
10.1007/s11239-020-02105-8
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Difference of coagulation features between severe pneumonia induced by SARS-CoV2 and non-SARS-CoV2. [Abstract]: Severe coronavirus disease 2019 (COVID-19) is commonly complicated with coagulopathy, the difference of coagulation features between severe pneumonia induced by SARS-CoV2 and non-SARS-CoV2 has not be...
32,680,626
J Pediatr Urol
A survey and panel discussion of the effects of the COVID-19 pandemic on paediatric urological productivity, guideline adherence and provider stress.
INTRODUCTION: The COVID-19 pandemic has led to an unprecedented need to re-organise and re-align priorities for all surgical specialties. Despite the current declining numbers globally, the direct effects of the pandemic on institutional practices and on personal stress and coping mechanisms remains unknown. The aims o...
covid-19;pss (perceived stress scale);pandemic;sars-cov-2;telemedicine;training
Journal Article;Multicenter Study
O'Kelly, Fardod;Sparks, Scott;Seideman, Casey;Gargollo, Patricio;Granberg, Candace;Ko, Joan;Malhotra, Neha;Hecht, Sarah;Swords, Kelly;Rowe, Courtney;Whittam, Ben;Spinoit, Anne-Francoise;Dudley, Anne;Ellison, Jonathan;Chu, David;Routh, Jonathan;Cannon, Glenn;Kokorowski, Paul;Koyle, Martin;Silay, Mesrur Selcuk
10.1016/j.jpurol.2020.06.024
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A survey and panel discussion of the effects of the COVID-19 pandemic on paediatric urological productivity, guideline adherence and provider stress. [Abstract]: INTRODUCTION: The COVID-19 pandemic has led to an unprecedented need to re-organise and re-align priorities for all surgical specialties. Despite the...
32,975,842
J Med Virol
COVID-19 in people living with HIV: Clinical implications of dynamics of the immune response to SARS-CoV-2.
Little evidence on coronavirus disease 2019 (COVID-19) in people living with HIV (PLWH) is currently available. We reported clinical and viroimmunological data of all HIV-positive patients admitted to our center with COVID-19 from March 1 to May 12, 2020. Overall, five patients were included: all were virologically-sup...
covid-19;hiv infection;sars-cov-2;immune response
Journal Article
Mondi, Annalisa;Cimini, Eleonora;Colavita, Francesca;Cicalini, Stefania;Pinnetti, Carmela;Matusali, Giulia;Casetti, Rita;Maeurer, Markus;Vergori, Alessandra;Mazzotta, Valentina;Gagliardini, Roberta;De Zottis, Federico;Schinina, Vincenzo;Girardi, Enrico;Puro, Vincenzo;Ippolito, Giuseppe;Vaia, Francesco;Capobianchi, Mari...
10.1002/jmv.26556
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: COVID-19 in people living with HIV: Clinical implications of dynamics of the immune response to SARS-CoV-2. [Abstract]: Little evidence on coronavirus disease 2019 (COVID-19) in people living with HIV (PLWH) is currently available. We reported clinical and viroimmunological data of all HIV-positive patients ad...
32,423,664
Nutr Metab Cardiovasc Dis
A close-up on COVID-19 and cardiovascular diseases.
AIMS: To analyze the potential mechanism of cardiovascular dysfunctions induced by Coronavirus Disease 2019 (COVID-19) and to evaluate more effective therapeutic pathways for patients with cardiovascular diseases. DATA SYNTHESIS: COVID-19 mainly invades the lungs, causing its serious damage. Studies found that COVID-19...
covid-19;cardiovascular disease;potential mechanism
Journal Article;Research Support, Non-U.S. Gov't;Review
Li, Gang;Hu, Rui;Gu, Xuefang
10.1016/j.numecd.2020.04.001
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: A close-up on COVID-19 and cardiovascular diseases. [Abstract]: AIMS: To analyze the potential mechanism of cardiovascular dysfunctions induced by Coronavirus Disease 2019 (COVID-19) and to evaluate more effective therapeutic pathways for patients with cardiovascular diseases. DATA SYNTHESIS: COVID-19 mainly i...
32,899,652
Int J Environ Res Public Health
New Ways of Working? A Rapid Exploration of Emerging Evidence Regarding the Care of Older People during COVID19.
Health and social care staff have had to quickly adapt, respond and improve teamwork, as a response to the COVID-19 pandemic. Our objective was to rapidly summarize the emerging evidence of new ways of working in the care of older people during this period. We conducted an exploration of the emerging evidence within th...
covid-19;health and social care;integrated care;new ways of working;older people;social media;teamwork
Journal Article
Ni She, Eidin;O'Donnell, Deirdre;O'Shea, Marie;Stokes, Diarmuid
10.3390/ijerph17186442
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: New Ways of Working? A Rapid Exploration of Emerging Evidence Regarding the Care of Older People during COVID19. [Abstract]: Health and social care staff have had to quickly adapt, respond and improve teamwork, as a response to the COVID-19 pandemic. Our objective was to rapidly summarize the emerging evidence...
32,594,325
Eur J Clin Microbiol Infect Dis
Influenza and respiratory syncytial virus infections in the oldest-old continent.
SARS-CoV-2 dramatically revealed the sudden impact of respiratory viruses in our lives. Influenza and respiratory syncytial virus (RSV) infections are associated with high rates of morbidity, mortality, and an important burden on healthcare systems worldwide, especially in elderly patients. The aim of this study was to...
geriatrics;influenza;oldest-old;pneumonia;respiratory syncytial virus
Journal Article;Multicenter Study
Boattini, Matteo;Almeida, Andre;Christaki, Eirini;Cruz, Lourenco;Antao, Diogo;Moreira, Maria Ines;Bianco, Gabriele;Iannaccone, Marco;Tsiolakkis, Georgios;Khattab, Elina;Kasapi, Diamanto;Charrier, Lorena;Tosatto, Valentina;Marques, Torcato Moreira;Cavallo, Rossana;Costa, Cristina
10.1007/s10096-020-03959-9
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Influenza and respiratory syncytial virus infections in the oldest-old continent. [Abstract]: SARS-CoV-2 dramatically revealed the sudden impact of respiratory viruses in our lives. Influenza and respiratory syncytial virus (RSV) infections are associated with high rates of morbidity, mortality, and an importa...
32,968,645
Cardiovasc Diagn Ther
Pulmonary vascular endothelial injury and acute pulmonary hypertension caused by COVID-19: the fundamental cause of refractory hypoxemia?
Coronavirus disease (COVID-19) is a severe infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that binds to the cells; angiotensin converting enzyme 2 (ACE2) receptor. In the first severe case of COVID-19 in Shenzhen city, we found that in addition to the typical clinical manifest...
ace2;coronavirus disease (covid-19);pulmonary hypertension;pulmonary vascular endothelium;refractory hypoxemia
Case Reports
Wang, Xinxin;Tu, Yunliang;Huang, Bin;Li, Yinfeng;Li, Yanyan;Zhang, Sheng;Lin, Yingxin;Huang, Lei;Zhang, Weixing;Luo, Hua
10.21037/cdt-20-429
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Pulmonary vascular endothelial injury and acute pulmonary hypertension caused by COVID-19: the fundamental cause of refractory hypoxemia? [Abstract]: Coronavirus disease (COVID-19) is a severe infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that binds to the cells; ang...
32,750,338
Curr Biol
On the evolutionary epidemiology of SARS-CoV-2.
There is no doubt that the novel coronavirus SARS-CoV-2 that causes COVID-19 is mutating and thus has the potential to adapt during the current pandemic. Whether this evolution will lead to changes in the transmission, the duration, or the severity of the disease is not clear. This has led to considerable scientific an...
Journal Article;Research Support, Non-U.S. Gov't
Day, Troy;Gandon, Sylvain;Lion, Sebastien;Otto, Sarah P
10.1016/j.cub.2020.06.031
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: On the evolutionary epidemiology of SARS-CoV-2. [Abstract]: There is no doubt that the novel coronavirus SARS-CoV-2 that causes COVID-19 is mutating and thus has the potential to adapt during the current pandemic. Whether this evolution will lead to changes in the transmission, the duration, or the severity of...
32,398,026
J Transl Med
Allo-priming as a universal anti-viral vaccine: protecting elderly from current COVID-19 and any future unknown viral outbreak.
BACKGROUND: We present the rationale for a novel allo-priming approach to serve the elderly as a universal anti-virus vaccine, as well serving to remodel the aging immune system in order to reverse immunosenescence and inflammaging. This approach has the potential to protect the most vulnerable from disease and provide...
covid-19;cell therapy;immunosenescence;immunotherapy;inflammaging;vaccine
Journal Article
Har-Noy, Michael;Or, Reuven
10.1186/s12967-020-02363-3
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Allo-priming as a universal anti-viral vaccine: protecting elderly from current COVID-19 and any future unknown viral outbreak. [Abstract]: BACKGROUND: We present the rationale for a novel allo-priming approach to serve the elderly as a universal anti-virus vaccine, as well serving to remodel the aging immune ...
32,656,221
Front Med (Lausanne)
Clinical Characteristics of COVID-19 Patients With Gastrointestinal Symptoms: An Analysis of Seven Patients in China.
Objectives: Patients with novel coronavirus disease 2019 (COVID-19) can present with gastrointestinal symptoms as their initial symptoms or as the main manifestations during disease progression, but the clinical characteristics of these patients are still unknown. Methods: We identified COVID-19 patients who admitted t...
2019-ncov;covid-19;sars-cov-2;diarrhea;digestive tract;gastrointestinal symptom
Journal Article
Ai, Jin-Wei;Zi, Hao;Wang, Yong;Huang, Qiao;Wang, Na;Li, Lu-Yao;Pei, Bin;Ji, Jianguang;Zeng, Xian-Tao
10.3389/fmed.2020.00308
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Clinical Characteristics of COVID-19 Patients With Gastrointestinal Symptoms: An Analysis of Seven Patients in China. [Abstract]: Objectives: Patients with novel coronavirus disease 2019 (COVID-19) can present with gastrointestinal symptoms as their initial symptoms or as the main manifestations during disease...
32,348,003
Catheter Cardiovasc Interv
The experience of treating patients with acute myocardial infarction under the COVID-19 epidemic.
Worldwide Coronavirus Disease 2019 (COVID-19) epidemic makes the management of acute myocardial infarction (AMI) more complicated, effective treatment without further dissemination is thus quite challenging. Recently, we successfully treated three representative AMI cases, by sharing these detailed procedures, we summa...
covid-19;acute myocardial infarction;pandemic;percutaneous coronary intervention;personnel protection equipment
Case Reports;Journal Article
Xiao, Zhichao;Xu, Chang;Wang, Daowen;Zeng, Hesong
10.1002/ccd.28951
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The experience of treating patients with acute myocardial infarction under the COVID-19 epidemic. [Abstract]: Worldwide Coronavirus Disease 2019 (COVID-19) epidemic makes the management of acute myocardial infarction (AMI) more complicated, effective treatment without further dissemination is thus quite challe...
33,000,663
Int J Audiol
Telehealth tinnitus therapy during the COVID-19 outbreak in the UK: uptake and related factors.
OBJECTIVE: The Audiology Department at the Royal Surrey County Hospital usually offers face-to-face audiologist-delivered cognitive behavioural therapy (CBT) for tinnitus rehabilitation. During COVID-19 lockdown, patients were offered telehealth CBT via video using a web-based platform. This study evaluated the proport...
tinnitus;audiology;covid-19;telehealth;video
Journal Article
Aazh, Hashir;Swanepoel, De Wet;Moore, Brian C J
10.1080/14992027.2020.1822553
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Telehealth tinnitus therapy during the COVID-19 outbreak in the UK: uptake and related factors. [Abstract]: OBJECTIVE: The Audiology Department at the Royal Surrey County Hospital usually offers face-to-face audiologist-delivered cognitive behavioural therapy (CBT) for tinnitus rehabilitation. During COVID-19 ...
32,835,078
Inform Med Unlocked
Structure-based drug designing towards the identification of potential anti-viral for COVID-19 by targeting endoribonuclease NSP15.
The world is facing health and economic havoc due to the Corona Virus Disease-2019 (COVID-19) pandemic. Given the number of affected people and the mortality rate, the virus is undoubtedly a serious threat to humanity. By analogy with earlier reports about Severe Acute Respiratory Syndrome (SARS-CoV) and Middle East Re...
covid-19;coronavirus;endoribonuclease;nsp15 inhibitors
Journal Article
Krishnan, D Anantha;Sangeetha, G;Vajravijayan, S;Nandhagopal, N;Gunasekaran, K
10.1016/j.imu.2020.100392
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Structure-based drug designing towards the identification of potential anti-viral for COVID-19 by targeting endoribonuclease NSP15. [Abstract]: The world is facing health and economic havoc due to the Corona Virus Disease-2019 (COVID-19) pandemic. Given the number of affected people and the mortality rate, the...
32,294,810
Crit Care Resusc
ANZICS guiding principles for complex decision making during the COVID-19 pandemic.
The global 2019 coronavirus disease (COVID-19) pandemic has led to major challenges in clinical decision making when the demand for intensive care exceeds local capacity. In order to promote consistent, transparent, objective and ethical decision making, the Australian and New Zealand Intensive Care Society (ANZICS) fo...
covid-19
Journal Article
Warrillow, Stephen;Austin, Danielle;Cheung, Winston;Close, Eliana;Holley, Anthony;Horgan, Ben;Jansen, Melanie;Joynt, Gavin;Lister, Paula;Moodie, Stewart;Nichol, Alistair;Nicholls, Mark;Peake, Sandra;Skowronski, George;Streat, Stephen;White, Ben;Willmott, Lindy
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: ANZICS guiding principles for complex decision making during the COVID-19 pandemic. [Abstract]: The global 2019 coronavirus disease (COVID-19) pandemic has led to major challenges in clinical decision making when the demand for intensive care exceeds local capacity. In order to promote consistent, transparent,...
32,746,738
Otolaryngol Head Neck Surg
Patients With Voice Prosthesis Rehabilitation During the COVID-19 Pandemic: Analyzing the Effectiveness of Remote Triage and Management.
OBJECTIVE: To describe a remote approach used with patients with voice prosthesis after laryngectomy during the COVID-19 pandemic and the resulting clinical outcomes in terms of voice prosthesis complications management, oncological monitoring, and psychophysical well-being. STUDY DESIGN: Prospective cohort study. SETT...
covid-19;management;total laryngectomy;voice prosthesis
Journal Article
Longobardi, Ylenia;Galli, Jacopo;D'Alatri, Lucia;Savoia, Vezio;Mari, Giorgia;Rigante, Mario;Passali, Giulio Cesare;Bussu, Francesco;Parrilla, Claudio
10.1177/0194599820948043
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Patients With Voice Prosthesis Rehabilitation During the COVID-19 Pandemic: Analyzing the Effectiveness of Remote Triage and Management. [Abstract]: OBJECTIVE: To describe a remote approach used with patients with voice prosthesis after laryngectomy during the COVID-19 pandemic and the resulting clinical outco...
32,652,308
Clin Gastroenterol Hepatol
Surveillance and Monitoring of Hepatocellular Carcinoma During the COVID-19 Pandemic.
The Coronavirus disease 2019 (COVID-19) pandemic is expected to have a long-lasting impact on the approach to care for patients at risk for and with hepatocellular carcinoma (HCC) due to the risks from potential exposure and resource reallocation. The goal of this document is to provide recommendations on HCC surveilla...
afp;alpha-fetoprotein;coronavirus;hcc;screening
Journal Article;Review
Mehta, Neil;Parikh, Neehar;Kelley, R Katie;Hameed, Bilal;Singal, Amit G
10.1016/j.cgh.2020.06.072
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Surveillance and Monitoring of Hepatocellular Carcinoma During the COVID-19 Pandemic. [Abstract]: The Coronavirus disease 2019 (COVID-19) pandemic is expected to have a long-lasting impact on the approach to care for patients at risk for and with hepatocellular carcinoma (HCC) due to the risks from potential e...
32,434,289
Korean J Anesthesiol
Perioperative considerations for COVID-19 patients: lessons learned from the pandemic -a case series.
Background: As the coronavirus disease 2019 (COVID-19) pandemic spreads globally, hospitals are rushing to adapt their facilities, which were not designed to deal with infections adequately. Here, we present the management of a suspected COVID-19 patient. Case: A 66-year-old man with a recent travel history, infective ...
covid-19;communication;coronavirus;infection control;pandemics;perioperative care;perioperative period;personal protective equipment
Case Reports
Yek, Jia Lin Jacklyn;Kiew, Sheng Chuu Anne;Ngu, James Chi-Yong;Lim, Jimmy Guan Cheng
10.4097/kja.20182
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Perioperative considerations for COVID-19 patients: lessons learned from the pandemic -a case series. [Abstract]: Background: As the coronavirus disease 2019 (COVID-19) pandemic spreads globally, hospitals are rushing to adapt their facilities, which were not designed to deal with infections adequately. Here, ...
32,413,821
Diabetes Metab Syndr
A review of modern technologies for tackling COVID-19 pandemic.
OBJECTIVE: Science and technology sector constituting of data science, machine learning and artificial intelligence are contributing towards COVID-19. The aim of the present study is to discuss the various aspects of modern technology used to fight against COVID-19 crisis at different scales, including medical image pr...
artificial intelligence;covid-19;epidemic;machine learning
Journal Article;Review
Kumar, Aishwarya;Gupta, Puneet Kumar;Srivastava, Ankita
10.1016/j.dsx.2020.05.008
[ 0, 1, 1, 1, 0, 0, 0 ]
[Title]: A review of modern technologies for tackling COVID-19 pandemic. [Abstract]: OBJECTIVE: Science and technology sector constituting of data science, machine learning and artificial intelligence are contributing towards COVID-19. The aim of the present study is to discuss the various aspects of modern technology ...
32,771,640
Int J Infect Dis
Increased Complement Receptor-3 levels in monocytes and granulocytes distinguish COVID-19 patients with pneumonia from those with mild symptoms.
BACKGROUND: The reasons why some patients with COVID-19 develop pneumonia and others do not are unclear. To better understand this, we used multiparameter flow cytometry to profile circulating leukocytes from non-immunocompromised adult patients with PCR-proven COVID-19 and specifically compared those with mild symptom...
covid-19;complement receptor 3;flow cytometry;hypoxia;immunology and inflammation;therapeutics
Journal Article
Gupta, Rajeev;Gant, Vanya Alasdair;Williams, Bryan;Enver, Tariq
10.1016/j.ijid.2020.08.004
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Increased Complement Receptor-3 levels in monocytes and granulocytes distinguish COVID-19 patients with pneumonia from those with mild symptoms. [Abstract]: BACKGROUND: The reasons why some patients with COVID-19 develop pneumonia and others do not are unclear. To better understand this, we used multiparameter...
33,005,516
Cureus
COVID-19 Associated Coagulopathy in the Setting of Underlying Malignancy.
Coronavirus disease 2019 (COVID-19) associated coagulopathy is a well-recognized predictor for morbidity and mortality in COVID-19 patients. Both deep vein thrombosis (DVT) and pulmonary embolism (PE) have been reported in COVID-19 patients. Nonetheless, there are no consensus guidelines on the use of therapeutic coagu...
covid-19 associated coagulopathy;deep venous thrombosis;metastatic ovarian cancer;pulmonary embolism
Case Reports
Lim, Su Lin;Chan, Kok Hoe;Slim, Jihad;Guron, Gunwant;Shaaban, Hamid S
10.7759/cureus.10095
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: COVID-19 Associated Coagulopathy in the Setting of Underlying Malignancy. [Abstract]: Coronavirus disease 2019 (COVID-19) associated coagulopathy is a well-recognized predictor for morbidity and mortality in COVID-19 patients. Both deep vein thrombosis (DVT) and pulmonary embolism (PE) have been reported in CO...
33,027,443
Rev Assoc Med Bras (1992)
Gastrointestinal emergency care during the COVID-19 pandemic: rapid communication.
OBJECTIVE: Social distancing during the COVID-19 pandemic has been associated with a decrease in the search for medical care. High-risk patients have avoided hospital environments fearing infection. We hypothesize that there was also a decrease in the search for medical care related to gastrointestinal emergencies. The...
Journal Article
Leite, Carine;Trindade, Eduardo Neubarth;Grillo, Leonardo Wagner;Trindade, Manoel Roberto Maciel
10.1590/1806-9282.66.9.1187
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Gastrointestinal emergency care during the COVID-19 pandemic: rapid communication. [Abstract]: OBJECTIVE: Social distancing during the COVID-19 pandemic has been associated with a decrease in the search for medical care. High-risk patients have avoided hospital environments fearing infection. We hypothesize th...
32,762,795
Euro Surveill
Epidemiology of measles during the COVID-19 pandemic, a description of the surveillance data, 29 EU/EEA countries and the United Kingdom, January to May 2020.
The number of measles cases declined in European Union/European Economic Area countries and the United Kingdom in 2020. Reported cases to The European Centre for Disease Prevention and Control decreased from 710 to 54 between January and May. Epidemic intelligence screening observed a similar trend. Under-diagnoses and...
covid-19;epidemics;measles;public health surveillance
Journal Article
Nicolay, Nathalie;Mirinaviciute, Grazina;Mollet, Thomas;Celentano, Lucia Pastore;Bacci, Sabrina
10.2807/1560-7917.ES.2020.25.31.2001390
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Epidemiology of measles during the COVID-19 pandemic, a description of the surveillance data, 29 EU/EEA countries and the United Kingdom, January to May 2020. [Abstract]: The number of measles cases declined in European Union/European Economic Area countries and the United Kingdom in 2020. Reported cases to Th...
32,660,877
Br J Oral Maxillofac Surg
Coronavirus antibody positive tests and continued use of personal protective equipment throughout the pandemic.
The COVID-19 pandemic has thrust not only a novel virus onto the world, but new challenges resulting in novel approaches. Governments have reduced regulation in order to facilitate timely advances to combat the disease. Antibody testing has rapidly been deployed but it is creating challenges for staff and patients. Mas...
antibody tests;covid-19;coronavirus;personal protective equipment;pandemic
Journal Article
Herron, J B T;Dennis, J;Brennan, P A
10.1016/j.bjoms.2020.06.021
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Coronavirus antibody positive tests and continued use of personal protective equipment throughout the pandemic. [Abstract]: The COVID-19 pandemic has thrust not only a novel virus onto the world, but new challenges resulting in novel approaches. Governments have reduced regulation in order to facilitate timely...
32,925,133
Work
A review of studies on the COVID-19 epidemic crisis disease with a preventive approach.
BACKGROUND: COVID-19 is a highly contagious acute respiratory syndrome and has been declared a pandemic in more than 209 countries worldwide. At the time of writing, no preventive vaccine has been developed and tested in the community. This study was conducted to review studies aimed at preventing the spread of the cor...
covid-19;pandemic;novel coronaviruses;prevention
Journal Article;Systematic Review
Arefi, Maryam Feiz;Poursadeqiyan, Mohsen
10.3233/WOR-203218
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A review of studies on the COVID-19 epidemic crisis disease with a preventive approach. [Abstract]: BACKGROUND: COVID-19 is a highly contagious acute respiratory syndrome and has been declared a pandemic in more than 209 countries worldwide. At the time of writing, no preventive vaccine has been developed and ...
32,391,578
J Dent Educ
Are dental schools adequately preparing dental students to face outbreaks of infectious diseases such as COVID-19?
The recent 2019-novel coronavirus (2019-nCoV, also known as SARS-CoV-2) has caused >2,622,571 confirmed cases of coronavirus disease 2019 (COVID-19) in >185 countries, and >182,359 deaths globally. More than 9000 healthcare workers have also been infected by 2019-nCoV. Prior to the present pandemic of COVID-19, there h...
Editorial;Historical Article
Ghai, Suhani
10.1002/jdd.12174
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Are dental schools adequately preparing dental students to face outbreaks of infectious diseases such as COVID-19? [Abstract]: The recent 2019-novel coronavirus (2019-nCoV, also known as SARS-CoV-2) has caused >2,622,571 confirmed cases of coronavirus disease 2019 (COVID-19) in >185 countries, and >182,359 dea...
32,830,167
J Epidemiol
Public Awareness, Individual Prevention Practice, and Psychological Effect at the Beginning of the COVID-19 Outbreak in China.
BACKGROUND: The COVID-19 has spread to more than 200 countries and territories. But less is known about the knowledge, protection behavior and anxiety regarding the outbreak among the general population. METHODS: A cross-sectional, population-based online survey was conducted in China and abroad from January 28 to Febr...
covid-19;awareness;prevention practice;psychology
Journal Article;Research Support, Non-U.S. Gov't
Han, Bingfeng;Zhao, Tianshuo;Liu, Bei;Liu, Hanyu;Zheng, Hui;Wan, Yongmei;Qiu, Jiayi;Zhuang, Hui;Cui, Fuqiang
10.2188/jea.JE20200148
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Public Awareness, Individual Prevention Practice, and Psychological Effect at the Beginning of the COVID-19 Outbreak in China. [Abstract]: BACKGROUND: The COVID-19 has spread to more than 200 countries and territories. But less is known about the knowledge, protection behavior and anxiety regarding the outbrea...
32,450,344
Pharmacol Res
Enhanced platelet inhibition treatment improves hypoxemia in patients with severe Covid-19 and hypercoagulability. A case control, proof of concept study.
Patients affected by severe coronavirus induced disease-2019 (Covid-19) often experience hypoxemia due to alveolar involvement and endothelial dysfunction, which leads to the formation of micro thrombi in the pulmonary capillary vessels. Both hypoxemia and a prothrombotic diathesis have been associated with more severe...
antiplatelet;coagulation;coronavirus;covid-19;d-dimer;respiratory failure
Clinical Trial, Phase II;Controlled Clinical Trial;Journal Article
Viecca, Maurizio;Radovanovic, Dejan;Forleo, Giovanni Battista;Santus, Pierachille
10.1016/j.phrs.2020.104950
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Enhanced platelet inhibition treatment improves hypoxemia in patients with severe Covid-19 and hypercoagulability. A case control, proof of concept study. [Abstract]: Patients affected by severe coronavirus induced disease-2019 (Covid-19) often experience hypoxemia due to alveolar involvement and endothelial d...
32,227,091
Clin Infect Dis
Novel Coronavirus Disease 2019 (COVID-19) Pneumonia Progression Course in 17 Discharged Patients: Comparison of Clinical and Thin-Section Computed Tomography Features During Recovery.
BACKGROUND: Our objective was to retrospectively analyze the evolution of clinical features and thin-section computed tomography (CT) imaging of novel coronavirus disease 2019 (COVID-19) pneumonia in 17 discharged patients. METHODS: Serial thin-section CT scans of 17 discharged patients with COVID-19 were obtained duri...
covid-19;computed tomography;novel coronavirus pneumonia;viral pneumonia
Journal Article
Han, Xiaoyu;Cao, Yukun;Jiang, Nanchuan;Chen, Yan;Alwalid, Osamah;Zhang, Xin;Gu, Jin;Dai, Meng;Liu, Jie;Zhu, Wanyue;Zheng, Chuansheng;Shi, Heshui
10.1093/cid/ciaa271
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Novel Coronavirus Disease 2019 (COVID-19) Pneumonia Progression Course in 17 Discharged Patients: Comparison of Clinical and Thin-Section Computed Tomography Features During Recovery. [Abstract]: BACKGROUND: Our objective was to retrospectively analyze the evolution of clinical features and thin-section comput...
32,541,493
Medicine (Baltimore)
The adverse skin reactions of health care workers using personal protective equipment for COVID-19.
In December 2019, a new coronavirus was found in Wuhan, Hubei Province, China, and spread rapidly throughout the country, attracting global attention. On February 11, the World Health Organization (WHO) officially named the disease caused by 2019-nCoV coronavirus disease 2019 (COVID-19). With the increasing number of c...
Journal Article
Hu, Kaihui;Fan, Jing;Li, Xueqin;Gou, Xin;Li, Xinyuan;Zhou, Xiang
10.1097/MD.0000000000020603
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The adverse skin reactions of health care workers using personal protective equipment for COVID-19. [Abstract]: In December 2019, a new coronavirus was found in Wuhan, Hubei Province, China, and spread rapidly throughout the country, attracting global attention. On February 11, the World Health Organization (W...
32,535,674
Bull Environ Contam Toxicol
The Impact of COVID-19 Partial Lockdown on Primary Pollutant Concentrations in the Atmosphere of Rio de Janeiro and Sao Paulo Megacities (Brazil).
As COVID-19 spread all over the world, most of the countries adopted some kind of restrictions to avoid the collapse of health systems. In Brazil, Sao Paulo and Rio the Janeiro, the two most populated cities in the country, were the first to determine social distancing. In this study, the impact of the social distancin...
atmospheric pollutants;brazil;covid-19;lockdown;social distancing
Journal Article
Siciliano, Bruno;Carvalho, Giovanna;da Silva, Cleyton Martins;Arbilla, Graciela
10.1007/s00128-020-02907-9
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Impact of COVID-19 Partial Lockdown on Primary Pollutant Concentrations in the Atmosphere of Rio de Janeiro and Sao Paulo Megacities (Brazil). [Abstract]: As COVID-19 spread all over the world, most of the countries adopted some kind of restrictions to avoid the collapse of health systems. In Brazil, Sao P...
32,539,586
Otolaryngol Head Neck Surg
Olfactory and Gustatory Dysfunction as an Early Identifier of COVID-19 in Adults and Children: An International Multicenter Study.
OBJECTIVE: To evaluate the prevalence and characteristics of olfactory or gustatory dysfunction in coronavirus disease 2019 (COVID-19) patients. STUDY DESIGN: Multicenter case series. SETTING: Five tertiary care hospitals (3 in China, 1 in France, 1 in Germany). SUBJECTS AND METHODS: In total, 394 polymerase chain reac...
covid-19;covid-19 screening;sars-cov-2;anosmia;dysgeusia;gustatory dysfunction;olfactory dysfunction
Journal Article;Multicenter Study;Research Support, Non-U.S. Gov't
Qiu, Chenghao;Cui, Chong;Hautefort, Charlotte;Haehner, Antje;Zhao, Jun;Yao, Qi;Zeng, Hui;Nisenbaum, Eric J;Liu, Li;Zhao, Yu;Zhang, Di;Levine, Corinna G;Cejas, Ivette;Dai, Qi;Zeng, Mei;Herman, Philippe;Jourdaine, Clement;de With, Katja;Draf, Julia;Chen, Bing;Jayaweera, Dushyantha T;Denneny, James C 3rd;Casiano, Roy;Yu, ...
10.1177/0194599820934376
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Olfactory and Gustatory Dysfunction as an Early Identifier of COVID-19 in Adults and Children: An International Multicenter Study. [Abstract]: OBJECTIVE: To evaluate the prevalence and characteristics of olfactory or gustatory dysfunction in coronavirus disease 2019 (COVID-19) patients. STUDY DESIGN: Multicent...
32,415,305
Jpn J Clin Oncol
When cancer encounters COVID-19 in China: what have we suffered, experienced and learned.
The outbreak of the coronavirus disease (COVID-19) occurred in Wuhan, China, in December 2019. As of 21 March 2020, this epidemic has spread to 179 countries with more than 200 000 confirmed cases and 8578 deaths. The outbreak has put enormous pressure on the medical establishment and even led to exhaustion of medical ...
covid-19;sars-cov-2;cancer;diagnosis;treatment
Journal Article
Chen, Haiyang;Wu, Xuan;Wang, Wei;Wang, Qiming
10.1093/jjco/hyaa077
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: When cancer encounters COVID-19 in China: what have we suffered, experienced and learned. [Abstract]: The outbreak of the coronavirus disease (COVID-19) occurred in Wuhan, China, in December 2019. As of 21 March 2020, this epidemic has spread to 179 countries with more than 200 000 confirmed cases and 8578 dea...
32,501,804
J Med Internet Res
Digital Health Strategies to Fight COVID-19 Worldwide: Challenges, Recommendations, and a Call for Papers.
The coronavirus disease (COVID-19) pandemic has created an urgent need for coordinated mechanisms to respond to the outbreak across health sectors, and digital health solutions have been identified as promising approaches to address this challenge. This editorial discusses the current situation regarding digital health...
covid-19;communication;coronavirus;digital health;digital technology;ehealth;epidemiology;health care;infodemiology;public health;review;surveillance
Editorial
Fagherazzi, Guy;Goetzinger, Catherine;Rashid, Mohammed Ally;Aguayo, Gloria A;Huiart, Laetitia
10.2196/19284
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Digital Health Strategies to Fight COVID-19 Worldwide: Challenges, Recommendations, and a Call for Papers. [Abstract]: The coronavirus disease (COVID-19) pandemic has created an urgent need for coordinated mechanisms to respond to the outbreak across health sectors, and digital health solutions have been ident...
32,513,659
BMJ
Characteristics and outcomes of pregnant women admitted to hospital with confirmed SARS-CoV-2 infection in UK: national population based cohort study.
OBJECTIVES: To describe a national cohort of pregnant women admitted to hospital with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the UK, identify factors associated with infection, and describe outcomes, including transmission of infection, for mothers and infants. DESIGN: Prospective nat...
Journal Article
Knight, Marian;Bunch, Kathryn;Vousden, Nicola;Morris, Edward;Simpson, Nigel;Gale, Chris;O'Brien, Patrick;Quigley, Maria;Brocklehurst, Peter;Kurinczuk, Jennifer J
10.1136/bmj.m2107
[ 0, 1, 0, 0, 1, 0, 0 ]
[Title]: Characteristics and outcomes of pregnant women admitted to hospital with confirmed SARS-CoV-2 infection in UK: national population based cohort study. [Abstract]: OBJECTIVES: To describe a national cohort of pregnant women admitted to hospital with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) i...
32,778,481
Eur J Obstet Gynecol Reprod Biol
Can a health care worker have sex in the time of COVID-19?
Covid-19 is not transmitted by sex but close proximity during the act could aide in spread of the disease. Health care workers by virtue of the nature of their work have higher chances of exposure to the virus and them indulging in sex needs risk reduction strategies.
covid-19;health care workers;sex
Letter
Naik, B Sadananda
10.1016/j.ejogrb.2020.07.059
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Can a health care worker have sex in the time of COVID-19? [Abstract]: Covid-19 is not transmitted by sex but close proximity during the act could aide in spread of the disease. Health care workers by virtue of the nature of their work have higher chances of exposure to the virus and them indulging in sex need...
32,436,460
Ther Adv Respir Dis
TNFalpha inhibitor may be effective for severe COVID-19: learning from toxic epidermal necrolysis.
Increased inflammatory cytokines [such as tumor necrosis factor alpha (TNFalpha) and interleukin-6 (IL-6)] are observed in COVID-19 patients, especially in the severe group. The phenomenon of a cytokine storm may be the central inducer of apoptosis of alveolar epithelial cells, which leads to rapid progression in sever...
covid-19;tnfalpha inhibitor;etanercept;toxic epidermal necrolysis
Journal Article;Review
Chen, Xue-Yan;Yan, Bing-Xi;Man, Xiao-Yong
10.1177/1753466620926800
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: TNFalpha inhibitor may be effective for severe COVID-19: learning from toxic epidermal necrolysis. [Abstract]: Increased inflammatory cytokines [such as tumor necrosis factor alpha (TNFalpha) and interleukin-6 (IL-6)] are observed in COVID-19 patients, especially in the severe group. The phenomenon of a cytoki...
32,864,332
Integr Med Res
Efficacy and safety of herbal medicine (Lianhuaqingwen) for treating COVID-19: A systematic review and meta-analysis.
Background: Lianhuaqingwen (LH) has been proven effective for influenza. However, the promotion of LH for the treatment of patients with COVID-19 remains controversial. Therefore, our study aimed to assess the efficacy and safety of Lianhuaqingwen (LH) in treating patients with COVID-19 by a systematic review and meta-...
covid-19;herbal medicine;lianhuaqingwen;meta-analysis;systematic review
Journal Article;Review
Liu, Ming;Gao, Ya;Yuan, Yuan;Yang, Kelu;Shi, Shuzhen;Tian, Jinhui;Zhang, Junhua
10.1016/j.imr.2020.100644
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Efficacy and safety of herbal medicine (Lianhuaqingwen) for treating COVID-19: A systematic review and meta-analysis. [Abstract]: Background: Lianhuaqingwen (LH) has been proven effective for influenza. However, the promotion of LH for the treatment of patients with COVID-19 remains controversial. Therefore, o...
32,162,995
J Dent Res
Coronavirus Disease 2019 (COVID-19): Emerging and Future Challenges for Dental and Oral Medicine.
The epidemic of coronavirus disease 2019 (COVID-19), originating in Wuhan, China, has become a major public health challenge for not only China but also countries around the world. The World Health Organization announced that the outbreaks of the novel coronavirus have constituted a public health emergency of internati...
dental education;dental practice management;dental public health;infection control;transmission;virology
Journal Article;Research Support, Non-U.S. Gov't
Meng, L;Hua, F;Bian, Z
10.1177/0022034520914246
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Coronavirus Disease 2019 (COVID-19): Emerging and Future Challenges for Dental and Oral Medicine. [Abstract]: The epidemic of coronavirus disease 2019 (COVID-19), originating in Wuhan, China, has become a major public health challenge for not only China but also countries around the world. The World Health Org...
33,034,142
Clin Exp Allergy
UK consensus statement on the diagnosis of inducible laryngeal obstruction in light of the COVID-19 pandemic.
Prior to the COVID-19 pandemic, laryngoscopy was the mandatory gold standard for the accurate assessment and diagnosis of inducible laryngeal obstruction. However, upper airway endoscopy is considered an aerosol-generating procedure in professional guidelines, meaning routine procedures are highly challenging and the a...
covid-19;inducible laryngeal obstruction;laryngoscopy
Journal Article
Haines, Jemma;Esposito, Karen;Slinger, Claire;Pargeter, Nicola;Murphy, Jennifer;Selby, Julia;Prior, Kathryn;Mansur, Adel;Vyas, Aashish;Stanton, Andrew E;Sabroe, Ian;Hull, James H;Fowler, Stephen J
10.1111/cea.13745
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: UK consensus statement on the diagnosis of inducible laryngeal obstruction in light of the COVID-19 pandemic. [Abstract]: Prior to the COVID-19 pandemic, laryngoscopy was the mandatory gold standard for the accurate assessment and diagnosis of inducible laryngeal obstruction. However, upper airway endoscopy is...
32,536,344
BMC Infect Dis
Potential implications of SARS-CoV-2 epidemic in Africa: where are we going from now?
The SARS-CoV-2, which emerged from East Asia in December 2019, has rapidly evolved into a global pandemic infecting close to 7 million people. The current uncertainties regarding its impact on Africa calls for critical monitoring of the evolution of the pandemic and correlation of factors that influence the burden of t...
africa;covid-19;coronavirus;low-income countries;sars-cov-2
Editorial
Torti, Carlo;Mazzitelli, Maria;Trecarichi, Enrico Maria;Darius, Owachi
10.1186/s12879-020-05147-8
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Potential implications of SARS-CoV-2 epidemic in Africa: where are we going from now? [Abstract]: The SARS-CoV-2, which emerged from East Asia in December 2019, has rapidly evolved into a global pandemic infecting close to 7 million people. The current uncertainties regarding its impact on Africa calls for cri...
32,741,657
Acad Radiol
Assessment of Small Pulmonary Blood Vessels in COVID-19 Patients Using HRCT.
RATIONALE AND OBJECTIVES: Mounting evidence supports the role of pulmonary hemodynamic alternations in the pathogenesis of COVID-19. Previous studies have demonstrated that changes in pulmonary blood volumes measured on computed tomography (CT) are associated with histopathological markers of pulmonary vascular pruning...
covid-19;pulmonary vascular disease;quantitative ct metrics
Journal Article;Research Support, Non-U.S. Gov't
Lins, Muriel;Vandevenne, Jan;Thillai, Muhunthan;Lavon, Ben R;Lanclus, Maarten;Bonte, Stijn;Godon, Rik;Kendall, Irvin;De Backer, Jan;De Backer, Wilfried
10.1016/j.acra.2020.07.019
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Assessment of Small Pulmonary Blood Vessels in COVID-19 Patients Using HRCT. [Abstract]: RATIONALE AND OBJECTIVES: Mounting evidence supports the role of pulmonary hemodynamic alternations in the pathogenesis of COVID-19. Previous studies have demonstrated that changes in pulmonary blood volumes measured on co...
32,965,603
Intern Emerg Med
Neither ACEIs nor ARBs are associated with respiratory distress or mortality in COVID-19 results of a prospective study on a hospital-based cohort.
Considerable concern has emerged for the potential harm in the use of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor inhibitors (ARBs) in COVID-19 patients, given that ACEIs and ARBs may increase the expression of ACE2 receptors that represent the way for coronavirus 2 to entry into the cell ...
angiotensin converting enzyme inhibitor;angiotensin receptor blocker;covid-19
Journal Article
Anzola, Gian Paolo;Bartolaminelli, Clara;Gregorini, Gina Alessandra;Coazzoli, Chiara;Gatti, Francesca;Mora, Alessandra;Charalampakis, Dimitrios;Palmigiano, Andrea;De Simone, Michele;Comini, Alice;Dellaglio, Erica;Cassetti, Salvatore;Chiesa, Maurizio;Spedini, Francesca;d'Ottavi, Patrizia;Savio, Maria Cristina
10.1007/s11739-020-02500-2
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Neither ACEIs nor ARBs are associated with respiratory distress or mortality in COVID-19 results of a prospective study on a hospital-based cohort. [Abstract]: Considerable concern has emerged for the potential harm in the use of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor inhibit...
32,589,146
JMIR Public Health Surveill
Statistical Issues and Lessons Learned From COVID-19 Clinical Trials With Lopinavir-Ritonavir and Remdesivir.
BACKGROUND: Recently, three randomized clinical trials on coronavirus disease (COVID-19) treatments were completed: one for lopinavir-ritonavir and two for remdesivir. One trial reported that remdesivir was superior to placebo in shortening the time to recovery, while the other two showed no benefit of the treatment un...
covid-19;coronavirus;cure rate model;restricted mean survival time;sample size adjustment;terminal event;type i error rate
Journal Article;Research Support, Non-U.S. Gov't
Yin, Guosheng;Zhang, Chenyang;Jin, Huaqing
10.2196/19538
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Statistical Issues and Lessons Learned From COVID-19 Clinical Trials With Lopinavir-Ritonavir and Remdesivir. [Abstract]: BACKGROUND: Recently, three randomized clinical trials on coronavirus disease (COVID-19) treatments were completed: one for lopinavir-ritonavir and two for remdesivir. One trial reported th...
32,340,751
Nefrologia
[Management of the SARS-CoV-2 (COVID-19) coronavirus epidemic in hemodialysis units].
The current outbreak of SARS-CoV-2 represents a special risk for renal patients due to their comorbidities and advanced age. The usual performance of hemodialysis treatments in collective rooms increases the risk. The specific information at this time in this regard is very limited. This manuscript includes a proposal ...
covid-19;coronavirus;hemodialysis;hemodialisis;sars-cov-2
Practice Guideline
Arenas, Maria Dolores;Villar, Judit;Gonzalez, Cristina;Cao, Higinio;Collado, Silvia;Crespo, Marta;Horcajada, Juan Pablo;Pascual, Julio
10.1016/j.nefro.2020.04.001
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Management of the SARS-CoV-2 (COVID-19) coronavirus epidemic in hemodialysis units]. [Abstract]: The current outbreak of SARS-CoV-2 represents a special risk for renal patients due to their comorbidities and advanced age. The usual performance of hemodialysis treatments in collective rooms increases the risk....
32,656,223
Front Med (Lausanne)
Re-positive Cases of Nucleic Acid Tests in Discharged Patients With COVID-19: A Follow-Up Study.
Background: The frequent emergence of the re-positive patients with COVID-19 is a potential threat worldwide. This study aimed to describe data from admission to follow-up for patients with COVID-19 and analyze the possible causes for re-positive nucleic acid tests to provide more scientific basis for reducing the numb...
covid-19;sars-cov-2;discharge;follow-up;re-positive
Journal Article
Qiao, Xi-Min;Xu, Xiao-Feng;Zi, Hao;Liu, Guo-Xiong;Li, Bing-Hui;Du, Xiang;Tian, Zhi-Hai;Liu, Xiao-Ying;Luo, Li-Sha;Wang, Xiao
10.3389/fmed.2020.00349
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Re-positive Cases of Nucleic Acid Tests in Discharged Patients With COVID-19: A Follow-Up Study. [Abstract]: Background: The frequent emergence of the re-positive patients with COVID-19 is a potential threat worldwide. This study aimed to describe data from admission to follow-up for patients with COVID-19 and...
32,849,446
Front Microbiol
Food Safety During and After the Era of COVID-19 Pandemic.
The coronavirus disease 2019 (COVID-19) is a clinical syndrome caused by severe acute respiratory syndrome corona virus-2 (SARS-CoV-2). COVID-19 was declared a pandemic by the World Health Organization (WHO) on March 11, 2020 due to its rapid and extensive spread among many countries through its very contagious nature ...
covid-19;sars-cov-2;active packaging;coronavirus;food package;food safety;sanitation;transmission
Journal Article
Olaimat, Amin N;Shahbaz, Hafiz M;Fatima, Nayab;Munir, Sadia;Holley, Richard A
10.3389/fmicb.2020.01854
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[Title]: Food Safety During and After the Era of COVID-19 Pandemic. [Abstract]: The coronavirus disease 2019 (COVID-19) is a clinical syndrome caused by severe acute respiratory syndrome corona virus-2 (SARS-CoV-2). COVID-19 was declared a pandemic by the World Health Organization (WHO) on March 11, 2020 due to its rap...
33,044,691
Adv Ther
Baseline Demographics and Clinical Characteristics Among 3471 US Patients Hospitalized with COVID-19 and Pulmonary Involvement: A Retrospective Study.
INTRODUCTION: Coronavirus disease 2019 (COVID-19) can present as a range of symptoms, from mild to critical; lower pulmonary involvement, including pneumonia, is often associated with severe and critical cases. Understanding the baseline characteristics of patients hospitalized with COVID-19 illness is essential for ef...
baseline characteristics;covid-19;coronavirus;demographics;hospitalized;infectious disease;pulmonary involvement
Journal Article;Research Support, Non-U.S. Gov't
Best, Jennie H;Mohan, Shalini V;Kong, Amanda M;Patel, Krish;Pagel, John M;Ivanov, Boris;Brawley, Otis W;Jariwala-Parikh, Krutika;Zazzali, James L;Pauk, John
10.1007/s12325-020-01510-y
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Baseline Demographics and Clinical Characteristics Among 3471 US Patients Hospitalized with COVID-19 and Pulmonary Involvement: A Retrospective Study. [Abstract]: INTRODUCTION: Coronavirus disease 2019 (COVID-19) can present as a range of symptoms, from mild to critical; lower pulmonary involvement, including ...
32,211,963
Eur Radiol
Coronavirus disease 2019: initial chest CT findings.
OBJECTIVES: To systematically analyze CT findings during the early and progressive stages of natural course of coronavirus disease 2019 and also to explore possible changes in pulmonary parenchymal abnormalities during these two stages. METHODS: We retrospectively reviewed the initial chest CT data of 62 confirmed coro...
covid-19;coronavirus;pneumonia;sars-cov-2;spiral ct scan
Journal Article
Zhou, Zhiming;Guo, Dajing;Li, Chuanming;Fang, Zheng;Chen, Linli;Yang, Ran;Li, Xiang;Zeng, Wenbing
10.1007/s00330-020-06816-7
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Coronavirus disease 2019: initial chest CT findings. [Abstract]: OBJECTIVES: To systematically analyze CT findings during the early and progressive stages of natural course of coronavirus disease 2019 and also to explore possible changes in pulmonary parenchymal abnormalities during these two stages. METHODS: ...
32,667,573
Rev Bras Enferm
Prevention and control measures for neonatal COVID-19 infection: a scoping review.
OBJECTIVE: to identify with the literature the measures to prevent and control neonatal infection by COVID-19. METHODS: a scope review carried out by searching for studies in databases and institutional health websites. The final sample was 25 articles. RESULTS: among the main measures are the use of masks by suspected...
Journal Article;Systematic Review
Freitas, Bruna Hinnah Borges Martins de;Alves, Mayrene Dias de Sousa Moreira;Gaiva, Maria Aparecida Munhoz
10.1590/0034-7167-2020-0467
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[Title]: Prevention and control measures for neonatal COVID-19 infection: a scoping review. [Abstract]: OBJECTIVE: to identify with the literature the measures to prevent and control neonatal infection by COVID-19. METHODS: a scope review carried out by searching for studies in databases and institutional health websit...
32,837,731
New Microbes New Infect
The current situation of COVID-19 in Sudan.
The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global public health concern with rapid growth in the number of patients with significant mortality rates. The first case in Sudan was reported on 13 March 2020, and up to 3 July 2020 there ar...
covid-19;sars-cov-2;sudan;current scenario;testing facilities
Journal Article
Altayb, H N;Altayeb, N M E;Hamadalnil, Y;Elsayid, M;Mahmoud, N E
10.1016/j.nmni.2020.100746
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The current situation of COVID-19 in Sudan. [Abstract]: The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global public health concern with rapid growth in the number of patients with significant mortality rates. The first case in Su...
32,937,615
JCI Insight
High levels of SARS-CoV-2-specific T cells with restricted functionality in severe courses of COVID-19.
BACKGROUNDPatients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) differ in the severity of disease. We hypothesized that characteristics of SARS-CoV-2-specific immunity correlate with disease severity.METHODSIn this study, SARS-CoV-2-specific T cells and antibodies were characterized in uni...
covid-19;cellular immune response;immunoglobulins;t cells
Journal Article;Research Support, Non-U.S. Gov't
Schub, David;Klemis, Verena;Schneitler, Sophie;Mihm, Janine;Lepper, Philipp M;Wilkens, Heinrike;Bals, Robert;Eichler, Hermann;Gartner, Barbara C;Becker, Soren L;Sester, Urban;Sester, Martina;Schmidt, Tina
10.1172/jci.insight.142167
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: High levels of SARS-CoV-2-specific T cells with restricted functionality in severe courses of COVID-19. [Abstract]: BACKGROUNDPatients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) differ in the severity of disease. We hypothesized that characteristics of SARS-CoV-2-specific immuni...
32,334,161
Sci Total Environ
Can we predict the occurrence of COVID-19 cases? Considerations using a simple model of growth.
This study aimed to present a simple model to follow the evolution of the COVID-19 (CV-19) pandemic in different countries. The cumulative distribution function (CDF) and its first derivative were employed for this task. The simulations showed that it is almost impossible to predict based on the initial CV-19 cases (1s...
coronavirus;cumulative distribution function;pandemic;sars-cov-2
Journal Article
Cassaro, Fabio A M;Pires, Luiz F
10.1016/j.scitotenv.2020.138834
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Can we predict the occurrence of COVID-19 cases? Considerations using a simple model of growth. [Abstract]: This study aimed to present a simple model to follow the evolution of the COVID-19 (CV-19) pandemic in different countries. The cumulative distribution function (CDF) and its first derivative were employ...
32,681,308
Eur J Clin Microbiol Infect Dis
Evaluations of the serological test in the diagnosis of 2019 novel coronavirus (SARS-CoV-2) infections during the COVID-19 outbreak.
We developed a chemiluminescence immunoassay method based on the recombinant nucleocapsid antigen and assessed its performance for the clinical diagnosis of severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infections by detecting SARS-CoV-2-specific IgM and IgG antibodies in patients. Full-length recombinant ...
chemiluminescence immunoassay;igm and igg;sars-cov-2;serological testing
Journal Article
Lin, Dachuan;Liu, Lei;Zhang, Mingxia;Hu, Yunlong;Yang, Qianting;Guo, Jiubiao;Dai, Youchao;Xu, Yuzhong;Cai, Yi;Chen, Xinchun;Huang, Kaisong;Zhang, Zheng
10.1007/s10096-020-03978-6
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Evaluations of the serological test in the diagnosis of 2019 novel coronavirus (SARS-CoV-2) infections during the COVID-19 outbreak. [Abstract]: We developed a chemiluminescence immunoassay method based on the recombinant nucleocapsid antigen and assessed its performance for the clinical diagnosis of severe ac...
32,624,495
BMJ Open Respir Res
Is continuous positive airway pressure (CPAP) a new standard of care for type 1 respiratory failure in COVID-19 patients? A retrospective observational study of a dedicated COVID-19 CPAP service.
The aim of this case series is to describe and evaluate our experience of continuous positive airway pressure (CPAP) to treat type 1 respiratory failure in patients with COVID-19. CPAP was delivered in negative pressure rooms in the newly repurposed infectious disease unit. We report a cohort of 24 patients with type 1...
non invasive ventilation;respiratory infection
Journal Article;Observational Study
Nightingale, Rebecca;Nwosu, Nneka;Kutubudin, Farheen;Fletcher, Tom;Lewis, Joe;Frost, Frederick;Haigh, Kathryn;Robinson, Ryan;Kumar, Ayesha;Jones, Gareth;Brown, Deborah;Abouyannis, Michael;Beadsworth, Mike;Hampshire, Peter;Aston, Stephen;Gautam, Manish;Burhan, Hassan
10.1136/bmjresp-2020-000639
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Is continuous positive airway pressure (CPAP) a new standard of care for type 1 respiratory failure in COVID-19 patients? A retrospective observational study of a dedicated COVID-19 CPAP service. [Abstract]: The aim of this case series is to describe and evaluate our experience of continuous positive airway pr...
32,398,876
Nat Med
A serological assay to detect SARS-CoV-2 seroconversion in humans.
Here, we describe a serological enzyme-linked immunosorbent assay for the screening and identification of human SARS-CoV-2 seroconverters. This assay does not require the handling of infectious virus, can be adjusted to detect different antibody types in serum and plasma and is amenable to scaling. Serological assays a...
Journal Article;Observational Study;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Amanat, Fatima;Stadlbauer, Daniel;Strohmeier, Shirin;Nguyen, Thi H O;Chromikova, Veronika;McMahon, Meagan;Jiang, Kaijun;Arunkumar, Guha Asthagiri;Jurczyszak, Denise;Polanco, Jose;Bermudez-Gonzalez, Maria;Kleiner, Giulio;Aydillo, Teresa;Miorin, Lisa;Fierer, Daniel S;Lugo, Luz Amarilis;Kojic, Erna Milunka;Stoever, Jonath...
10.1038/s41591-020-0913-5
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: A serological assay to detect SARS-CoV-2 seroconversion in humans. [Abstract]: Here, we describe a serological enzyme-linked immunosorbent assay for the screening and identification of human SARS-CoV-2 seroconverters. This assay does not require the handling of infectious virus, can be adjusted to detect diffe...
32,436,262
Dermatol Ther
Hidden threat lurking behind the alcohol sanitizers in COVID-19 outbreak.
The ongoing COVID-19 pandemic has made various challenges for communications all over the world. Nowadays hand hygiene practices with alcohol sanitizers are an unavoidable reality for many people, which cause skin dryness and flaking. The current short communication has been explained about monitoring the quality contr...
covid-19;alcohol concentrations;hand dermatitis
Journal Article;Review
Emami, Amir;Javanmardi, Fatemeh;Keshavarzi, Abdolkhalegh;Pirbonyeh, Neda
10.1111/dth.13627
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Hidden threat lurking behind the alcohol sanitizers in COVID-19 outbreak. [Abstract]: The ongoing COVID-19 pandemic has made various challenges for communications all over the world. Nowadays hand hygiene practices with alcohol sanitizers are an unavoidable reality for many people, which cause skin dryness and...
32,524,832
Antioxid Redox Signal
Is Albumin Predictor of Mortality in COVID-19?
Coronavirus 2019 (COVID-19) is a pandemic associated with a high risk of mortality. Human serum albumin (HSA) is an acute phase reactant with antioxidant property; however, its behavior and impact on survival in COVID-19 patients have never been studied so far. Among 319 COVID-19 patients followed up for a median of 19...
covid-19;albumin;mortality
Journal Article
Violi, Francesco;Cangemi, Roberto;Romiti, Giulio Francesco;Ceccarelli, Giancarlo;Oliva, Alessandra;Alessandri, Francesco;Pirro, Matteo;Pignatelli, Pasquale;Lichtner, Miriam;Carraro, Anna;Cipollone, Francesco;D'Ardes, Damiano;Pugliese, Francesco;Mastroianni, Claudio Maria
10.1089/ars.2020.8142
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Is Albumin Predictor of Mortality in COVID-19? [Abstract]: Coronavirus 2019 (COVID-19) is a pandemic associated with a high risk of mortality. Human serum albumin (HSA) is an acute phase reactant with antioxidant property; however, its behavior and impact on survival in COVID-19 patients have never been studie...
33,005,547
Cureus
Regional Anesthesia Practices in Turkey During the COVID-19 Pandemic.
Introduction The aim of the survey was to investigate the changes, methods, and preferences in regional anesthesia (RA) applications during the COVID-19 pandemic in Turkey. Methods The questionnaire prepared on surveymonkey.com was sent to anesthesiology and reanimation specialists by e-mail. Results A total of 126 phy...
covid-19;peripheral nerve blocks;regional anaesthesia;survey research;ultrasound-guided
Journal Article
Cesur, Sevim;Aksu, Can;Kus, Alparslan
10.7759/cureus.10135
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Regional Anesthesia Practices in Turkey During the COVID-19 Pandemic. [Abstract]: Introduction The aim of the survey was to investigate the changes, methods, and preferences in regional anesthesia (RA) applications during the COVID-19 pandemic in Turkey. Methods The questionnaire prepared on surveymonkey.com w...