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32,713,410
Disaster Med Public Health Prep
Maximizing Health-Care Capacity in Response to COVID-19 Outbreak: Rapid Expansion Through Education by Health Emergency and Disaster Experts.
Delivering adequate health care in the setting of the ongoing pandemic is challenging. Due to coronavirus disease 2019 (COVID-19), the Tokyo Metropolitan government has been forced to expand their acute health-care capacity corresponding to infectious diseases within a short period. Responding to this situation, health...
disaster medicine;disaster planning;emergency medical services;emergency medicine;emergency preparedness
Journal Article
Kato, Soichiro;Miyakuni, Yasuhiko;Inoue, Yoshitaka;Yamaguchi, Yoshihiro
10.1017/dmp.2020.264
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Maximizing Health-Care Capacity in Response to COVID-19 Outbreak: Rapid Expansion Through Education by Health Emergency and Disaster Experts. [Abstract]: Delivering adequate health care in the setting of the ongoing pandemic is challenging. Due to coronavirus disease 2019 (COVID-19), the Tokyo Metropolitan gov...
32,227,493
J Med Virol
Novel coronavirus treatment with ribavirin: Groundwork for an evaluation concerning COVID-19.
Confronting the challenge of the outbreak of COVID-19 should sharpen our focus on global drug access as a key issue in antiviral therapy testing. The testing and adoption of effective therapies for novel coronaviruses are hampered by the challenge of conducting controlled studies during a state of emergency. The access...
covid-19;novel coronavirus;ribavirin
Journal Article;Review
Khalili, Jahan S;Zhu, Hai;Mak, Nga Sze Amanda;Yan, Yongqi;Zhu, Yi
10.1002/jmv.25798
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Novel coronavirus treatment with ribavirin: Groundwork for an evaluation concerning COVID-19. [Abstract]: Confronting the challenge of the outbreak of COVID-19 should sharpen our focus on global drug access as a key issue in antiviral therapy testing. The testing and adoption of effective therapies for novel c...
32,361,455
Sci Total Environ
Modelling spatial variations of coronavirus disease (COVID-19) in Africa.
Clinical and epidemiological evidence has been advanced for human-to-human transmission of the novel coronavirus rampaging the world since late 2019. Outliers in the human-to-human transmission are yet to be explored. In this study, we examined the spatial density and leaned statistical credence to the global debate. W...
africa;covid-19 attributable deaths;covid-19 confirmed cases;spatial variation;system gmm
Journal Article
Adekunle, Ibrahim Ayoade;Onanuga, Abayomi Toyin;Akinola, Olanrewaju Olugbenga;Ogunbanjo, Olakitan Wahab
10.1016/j.scitotenv.2020.138998
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Modelling spatial variations of coronavirus disease (COVID-19) in Africa. [Abstract]: Clinical and epidemiological evidence has been advanced for human-to-human transmission of the novel coronavirus rampaging the world since late 2019. Outliers in the human-to-human transmission are yet to be explored. In this...
32,533,768
Rhinology
Time scale for resolution of olfactory dysfunction in COVID-19.
By now, the 2019 novel coronavirus disease (COVID-19), caused by the SARS-CoV-2 virus, is widely recognized around the world as a pandemic that has infected millions and claimed the lives of hundreds of thousands (1). Despite months of mitigation strategies, COVID-19 continues to spread and ascertainment of new knowled...
Journal Article
Speth, M M;Singer-Cornelius, T;Oberle, M;Gengler, I;Brockmeier, S J;Sedaghat, A R
10.4193/Rhin20.227
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Time scale for resolution of olfactory dysfunction in COVID-19. [Abstract]: By now, the 2019 novel coronavirus disease (COVID-19), caused by the SARS-CoV-2 virus, is widely recognized around the world as a pandemic that has infected millions and claimed the lives of hundreds of thousands (1). Despite months of...
32,790,942
Int J Clin Pract
Stay at Home, Protect the National Health Service, Save Lives: A cost benefit analysis of the lockdown in the United Kingdom.
INTRODUCTION: The COVID-19 pandemic has transformed lives across the world. In the UK, a public health driven policy of population "lockdown" has had enormous personal and economic impact. METHODS: We compare UK response and outcomes with European countries of similar income and healthcare resources. We calibrate estim...
covid-19;economics;strategy;unlock
Journal Article
Miles, David K;Stedman, Michael;Heald, Adrian H
10.1111/ijcp.13674
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Stay at Home, Protect the National Health Service, Save Lives: A cost benefit analysis of the lockdown in the United Kingdom. [Abstract]: INTRODUCTION: The COVID-19 pandemic has transformed lives across the world. In the UK, a public health driven policy of population "lockdown" has had enormous personal and e...
32,896,226
J Biomol Struct Dyn
In-silico screening of plant-derived antivirals against main protease, 3CL(pro) and endoribonuclease, NSP15 proteins of SARS-CoV-2.
Novel Coronavirus or SARS-CoV-2 outbreak has developed a pandemic condition all over the world. The virus is highly infectious and spreads by human to human local transmission mode. Till date, there is no vaccination or drugs been approved for the treatment by the World Health Organisation. Henceforth, the discovery of...
3clpro;covid-19;sars-cov-2;docking;endoribonuclease;plant-derived compounds
Journal Article
Sharma, Aniket;Goyal, Shubham;Yadav, Arvind Kumar;Kumar, Pawan;Gupta, Lovely
10.1080/07391102.2020.1808077
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: In-silico screening of plant-derived antivirals against main protease, 3CL(pro) and endoribonuclease, NSP15 proteins of SARS-CoV-2. [Abstract]: Novel Coronavirus or SARS-CoV-2 outbreak has developed a pandemic condition all over the world. The virus is highly infectious and spreads by human to human local tran...
32,285,930
Clin Pharmacol Ther
Optimizing Hydroxychloroquine Dosing for Patients With COVID-19: An Integrative Modeling Approach for Effective Drug Repurposing.
Hydroxychloroquine (HCQ) is a promising candidate for Coronavirus disease of 2019 (COVID-19) treatment. The optimal dosing of HCQ is unknown. Our goal was to integrate historic and emerging pharmacological and toxicity data to understand safe and efficacious HCQ dosing strategies for COVID-19 treatment. The data source...
Journal Article
Garcia-Cremades, Maria;Solans, Belen P;Hughes, Emma;Ernest, Jacqueline P;Wallender, Erika;Aweeka, Francesca;Luetkemeyer, Anne F;Savic, Radojka M
10.1002/cpt.1856
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Optimizing Hydroxychloroquine Dosing for Patients With COVID-19: An Integrative Modeling Approach for Effective Drug Repurposing. [Abstract]: Hydroxychloroquine (HCQ) is a promising candidate for Coronavirus disease of 2019 (COVID-19) treatment. The optimal dosing of HCQ is unknown. Our goal was to integrate h...
32,752,270
Biomolecules
Viral Ubiquitin and Ubiquitin-Like Deconjugases-Swiss Army Knives for Infection.
Posttranslational modifications of cellular proteins by covalent conjugation of ubiquitin and ubiquitin-like polypeptides regulate numerous cellular processes that are captured by viruses to promote infection, replication, and spreading. The importance of these protein modifications for the viral life cycle is undersco...
coronavirus;herpesvirus;innate immunity;type i ifn;ubiquitin-like deconjugase;virus cycle
Journal Article;Research Support, Non-U.S. Gov't;Review
Masucci, Maria Grazia
10.3390/biom10081137
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Viral Ubiquitin and Ubiquitin-Like Deconjugases-Swiss Army Knives for Infection. [Abstract]: Posttranslational modifications of cellular proteins by covalent conjugation of ubiquitin and ubiquitin-like polypeptides regulate numerous cellular processes that are captured by viruses to promote infection, replicat...
32,255,437
Indian Pediatr
Radiographic and Clinical Features of Children With Coronavirus Disease (COVID-19) Pneumonia.
OBJECTIVE: The purpose of this study was to investigate chest computed tomography (CT) findings in children with coronavirus disease-19 (COVID-19) pneumonia in our hospital. METHODS: This study included 22 pediatric patients with confirmed COVID-19 from January to March, 2020. The chest CT images and clinical data were...
Journal Article
Li, Bo;Shen, Jie;Li, Liang;Yu, Chengxin
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Radiographic and Clinical Features of Children With Coronavirus Disease (COVID-19) Pneumonia. [Abstract]: OBJECTIVE: The purpose of this study was to investigate chest computed tomography (CT) findings in children with coronavirus disease-19 (COVID-19) pneumonia in our hospital. METHODS: This study included 22...
32,744,714
Eur Rev Med Pharmacol Sci
Clinical features, laboratory findings and predictors of death in hospitalized patients with COVID-19 in Sardinia, Italy.
OBJECTIVE: Since December 2019, when the first SARS-CoV2 infections have been reported, the number of cases has increased exponentially. In our University Hospital Unit, the first patient with COVID-19 was admitted on the 8th of March 2020. We aimed to investigate the predictors of death among inpatients with COVID-19....
Journal Article
De Vito, A;Geremia, N;Fiore, V;Princic, E;Babudieri, S;Madeddu, G
10.26355/eurrev_202007_22291
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical features, laboratory findings and predictors of death in hospitalized patients with COVID-19 in Sardinia, Italy. [Abstract]: OBJECTIVE: Since December 2019, when the first SARS-CoV2 infections have been reported, the number of cases has increased exponentially. In our University Hospital Unit, the fir...
32,568,027
J Gen Virol
SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology.
The sudden emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the end of 2019 from the Chinese province of Hubei and its subsequent pandemic spread highlight the importance of understanding the full molecular details of coronavirus infection and pathogenesis. Here, we compared a variety of rep...
rna synthesis;antisera;antiviral drugs;evolution;furin-like cleavage site;plaque phenotype
Comparative Study;Journal Article
Ogando, Natacha S;Dalebout, Tim J;Zevenhoven-Dobbe, Jessika C;Limpens, Ronald W A L;van der Meer, Yvonne;Caly, Leon;Druce, Julian;de Vries, Jutte J C;Kikkert, Marjolein;Barcena, Montserrat;Sidorov, Igor;Snijder, Eric J
10.1099/jgv.0.001453
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology. [Abstract]: The sudden emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the end of 2019 from the Chinese province of Hubei and its subsequent pandemic spread highlight the impo...
32,523,929
Eur J Case Rep Intern Med
Respiratory Distress in SARS-CoV-2 without Lung Damage: Phrenic Paralysis Should Be Considered in COVID-19 Infection.
We describe an overweight COVID-19 patient with respiratory distress preceded by anosmia/dysgeusia with no lung injury shown on CT, angio-CT or ventilation/perfusion scans. Orthopnoea and paradoxical abdominal respiration were identified. Phrenic paralysis, demonstrated by examination of patient breathing, and on x-ray...
covid-19;neurotropism;phrenic paralysis;respiratory distress
Journal Article
Maurier, Francois;Godbert, Benoit;Perrin, Julie
10.12890/2020_001728
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Respiratory Distress in SARS-CoV-2 without Lung Damage: Phrenic Paralysis Should Be Considered in COVID-19 Infection. [Abstract]: We describe an overweight COVID-19 patient with respiratory distress preceded by anosmia/dysgeusia with no lung injury shown on CT, angio-CT or ventilation/perfusion scans. Orthopno...
32,924,650
Expert Rev Anti Infect Ther
The effect of antivirals on COVID-19: a systematic review.
INTRODUCTION: Coronavirus Disease 2019 is a contagious infection that has infected millions worldwide. The objective of this systematic review is to identify studies pertaining to antivirals, both as sole and combined therapies, in COVID-19 patients and review the clinical outcomes of these treatment methods. AREAS COV...
covid-19;antiviral;coronavirus;treatment
Journal Article
Hussain, Nafisa;Yoganathan, Anusha;Hewage, Savini;Alom, Samiha;Harky, Amer
10.1080/14787210.2021.1823832
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: The effect of antivirals on COVID-19: a systematic review. [Abstract]: INTRODUCTION: Coronavirus Disease 2019 is a contagious infection that has infected millions worldwide. The objective of this systematic review is to identify studies pertaining to antivirals, both as sole and combined therapies, in COVID-19...
32,682,004
Thromb Res
Pulmonary embolism in hospitalised patients with COVID-19.
BACKGROUND: Coronavirus disease 2019 (COVID-19) is characterised by dyspnoea and abnormal coagulation parameters, including raised D-dimer. Data suggests a high incidence of pulmonary embolism (PE) in ventilated patients with COVID-19. OBJECTIVES: To determine the incidence of PE in hospitalised patients with COVID-19 ...
covid-19;coronavirus;d-dimer;pulmonary embolism
Journal Article
Whyte, Martin B;Kelly, Philip A;Gonzalez, Elisa;Arya, Roopen;Roberts, Lara N
10.1016/j.thromres.2020.07.025
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Pulmonary embolism in hospitalised patients with COVID-19. [Abstract]: BACKGROUND: Coronavirus disease 2019 (COVID-19) is characterised by dyspnoea and abnormal coagulation parameters, including raised D-dimer. Data suggests a high incidence of pulmonary embolism (PE) in ventilated patients with COVID-19. OBJE...
32,967,312
J Clin Med
Retrospective Analysis of a Modified Organizational Model to Guarantee CT Workflow during the COVID-19 Outbreak in the Tertiary Hospital of Padova, Italy.
At the beginning of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) outbreak in Italy, the cluster of Vo Euganeo was managed by the University Hospital of Padova. The Department of Diagnostic Imaging (DDI) conceived an organizational approach based on three different pathways for low-risk, high-risk, an...
covid-19;computed tomography;organizational model;outbreak;preparedness;radiology
Journal Article
Cester, Giacomo;Giraudo, Chiara;Causin, Francesco;Boemo, Deris Gianni;Anglani, Mariagiulia;Capizzi, Alfio;Carretta, Giovanni;Cattelan, Annamaria;Cecchin, Diego;Cianci, Vito;Crisanti, Andrea;De Conti, Giorgio;Donato, Daniele;Flor, Luciano;Gabrieli, Joseph-Domenico;Munari, Marina;Navalesi, Paolo;Ponzoni, Alberto;Scapella...
10.3390/jcm9093042
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Retrospective Analysis of a Modified Organizational Model to Guarantee CT Workflow during the COVID-19 Outbreak in the Tertiary Hospital of Padova, Italy. [Abstract]: At the beginning of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) outbreak in Italy, the cluster of Vo Euganeo was managed by ...
32,904,353
Mater Today Proc
Predicting the Time Period of Extension of Lockdown due to Increase in Rate of COVID-19 Cases in India using Machine Learning.
The research paper proposes a methodology to predict the extension of lockdown in order to eradicate COVID-19 from India. All the concepts related to Coronavirus, its history, prevention and cure is explained in the research paper. Concept used to predict the number of active cases, deaths and recovery is Linear Regres...
covid-19;covid-19 pandemic;coronavirus india;coronavirus pandemic;coronavirus;lockdown prediction
Journal Article
Wadhwa, Parth;Aishwarya;Tripathi, Amrendra;Singh, Prabhishek;Diwakar, Manoj;Kumar, Neeraj
10.1016/j.matpr.2020.08.509
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Predicting the Time Period of Extension of Lockdown due to Increase in Rate of COVID-19 Cases in India using Machine Learning. [Abstract]: The research paper proposes a methodology to predict the extension of lockdown in order to eradicate COVID-19 from India. All the concepts related to Coronavirus, its histo...
32,306,492
J Thromb Haemost
D-dimer levels on admission to predict in-hospital mortality in patients with Covid-19.
BACKGROUND: The outbreak of the coronavirus disease 2019 (Covid-19) has shown a global spreading trend. Early and effective predictors of clinical outcomes are urgently needed to improve management of Covid-19 patients. OBJECTIVE: The aim of the present study was to evaluate whether elevated D-dimer levels could predic...
d-dimer;sars-cov-2;coronavirus disease;mortality;prognosis
Journal Article;Research Support, Non-U.S. Gov't
Zhang, Litao;Yan, Xinsheng;Fan, Qingkun;Liu, Haiyan;Liu, Xintian;Liu, Zejin;Zhang, Zhenlu
10.1111/jth.14859
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: D-dimer levels on admission to predict in-hospital mortality in patients with Covid-19. [Abstract]: BACKGROUND: The outbreak of the coronavirus disease 2019 (Covid-19) has shown a global spreading trend. Early and effective predictors of clinical outcomes are urgently needed to improve management of Covid-19 p...
32,614,889
PLoS One
Elderly people and responses to COVID-19 in 27 Countries.
Amongst the most robust consensus related to the COVID-19 disease is that the elderly are by far the most vulnerable population group. Hence, public authorities target older people in order to convince them to comply with preventive measures. However, we still know little about older people's attitudes and compliance t...
Journal Article
Daoust, J-F
10.1371/journal.pone.0235590
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Elderly people and responses to COVID-19 in 27 Countries. [Abstract]: Amongst the most robust consensus related to the COVID-19 disease is that the elderly are by far the most vulnerable population group. Hence, public authorities target older people in order to convince them to comply with preventive measures...
32,634,589
Int J Infect Dis
A potentially effective treatment for COVID-19: A systematic review and meta-analysis of convalescent plasma therapy in treating severe infectious disease.
BACKGROUND: Convalescent plasma (CP) has been used successfully to treat many types of infectious disease, and has shown initial effects in the treatment of the emerging 2019 coronavirus disease (COVID-19). However, its curative effects and feasibility have yet to be confirmed by formal evaluation and well-designed cli...
convalescent plasma (cp);coronavirus disease 2019 (covid-19);infectious disease;meta-analysis
Journal Article;Meta-Analysis;Systematic Review
Sun, Mengyao;Xu, Yinghui;He, Hua;Zhang, Li;Wang, Xu;Qiu, Qing;Sun, Chao;Guo, Ye;Qiu, Shi;Ma, Kewei
10.1016/j.ijid.2020.06.107
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: A potentially effective treatment for COVID-19: A systematic review and meta-analysis of convalescent plasma therapy in treating severe infectious disease. [Abstract]: BACKGROUND: Convalescent plasma (CP) has been used successfully to treat many types of infectious disease, and has shown initial effects in the...
33,031,477
PLoS One
Increased microbial loading in aerosols produced by non-contact air-puff tonometer and relative suggestions for the prevention of coronavirus disease 2019 (COVID-19).
OBJECTIVE: To evaluate the microbial loading in aerosols produced after air-puff by non-contact tonometer (NCT) as well as the effect of alcohol disinfection on the inhibition of microbes and thus to provide suggestions for the prevention and control of COVID-19 in ophthalmic departments of hospitals or clinics during ...
Journal Article;Research Support, Non-U.S. Gov't
Guo, Hui;Li, Wei;Huang, Yingying;Li, Xiaoyan;Li, Zhi;Zhou, Hongxia;Sun, Enhua;Li, Li;Li, Jisheng
10.1371/journal.pone.0240421
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Increased microbial loading in aerosols produced by non-contact air-puff tonometer and relative suggestions for the prevention of coronavirus disease 2019 (COVID-19). [Abstract]: OBJECTIVE: To evaluate the microbial loading in aerosols produced after air-puff by non-contact tonometer (NCT) as well as the effec...
32,367,431
Front Med
Neurological manifestations of patients with COVID-19: potential routes of SARS-CoV-2 neuroinvasion from the periphery to the brain.
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2), has caused a global pandemic in only 3 months. In addition to major respiratory distress, characteristic neurological manifestations are also described, indicating that SARS-CoV-2 may be an underestimated opport...
sars-cov-2;brain;coronavirus disease 2019 (covid-19);neuroinvasion;neurological manifestations
Journal Article;Review
Li, Zhengqian;Liu, Taotao;Yang, Ning;Han, Dengyang;Mi, Xinning;Li, Yue;Liu, Kaixi;Vuylsteke, Alain;Xiang, Hongbing;Guo, Xiangyang
10.1007/s11684-020-0786-5
[ 0, 0, 1, 1, 0, 0, 0 ]
[Title]: Neurological manifestations of patients with COVID-19: potential routes of SARS-CoV-2 neuroinvasion from the periphery to the brain. [Abstract]: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2), has caused a global pandemic in only 3 months. In additio...
32,701,430
Prev Chronic Dis
The Role of Public Health in COVID-19 Emergency Response Efforts From a Rural Health Perspective.
As the country responds to coronavirus disease 2019 (COVID-19), the role of public health in ensuring the delivery of equitable health care in rural communities has not been fully appreciated. The impact of such crises is exacerbated in rural racial/ethnic minority communities. Various elements contribute to the proble...
Journal Article
Melvin, Sandra C;Wiggins, Corey;Burse, Nakeitra;Thompson, Erica;Monger, Mauda
10.5888/pcd17.200256
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Role of Public Health in COVID-19 Emergency Response Efforts From a Rural Health Perspective. [Abstract]: As the country responds to coronavirus disease 2019 (COVID-19), the role of public health in ensuring the delivery of equitable health care in rural communities has not been fully appreciated. The impa...
32,379,016
Disaster Med Public Health Prep
Incorporating Issues of Elderly Loneliness into the Coronavirus Disease-2019 Public Health Response.
As the systems that people depend on are increasingly strained by the coronavirus disease-2019 (COVID-19) outbreak, public health impacts are manifesting in different ways beyond morbidity and mortality for elderly populations. Loneliness is already a chief public health concern that is being made worse by COVID-19. Ag...
covid-19;decision-making;elderly;loneliness;public health emergency response;resilience;vulnerable populations
Letter;Research Support, N.I.H., Extramural
Patel, Sonny S;Clark-Ginsberg, Aaron
10.1017/dmp.2020.145
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Incorporating Issues of Elderly Loneliness into the Coronavirus Disease-2019 Public Health Response. [Abstract]: As the systems that people depend on are increasingly strained by the coronavirus disease-2019 (COVID-19) outbreak, public health impacts are manifesting in different ways beyond morbidity and morta...
32,986,528
J Clin Oncol
COVID-19 Severity and Outcomes in Patients With Cancer: A Matched Cohort Study.
PURPOSE: SARS-CoV-2 (COVID-19) is a systemic infection. Patients with cancer are immunocompromised and may be vulnerable to COVID-related morbidity and mortality. The objectives of this study were to determine if patients with cancer have worse outcomes compared with patients without cancer and to identify demographic ...
Journal Article;Research Support, N.I.H., Extramural
Brar, Gagandeep;Pinheiro, Laura C;Shusterman, Michael;Swed, Brandon;Reshetnyak, Evgeniya;Soroka, Orysya;Chen, Frank;Yamshon, Samuel;Vaughn, John;Martin, Peter;Paul, Doru;Hidalgo, Manuel;Shah, Manish A
10.1200/JCO.20.01580
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 Severity and Outcomes in Patients With Cancer: A Matched Cohort Study. [Abstract]: PURPOSE: SARS-CoV-2 (COVID-19) is a systemic infection. Patients with cancer are immunocompromised and may be vulnerable to COVID-related morbidity and mortality. The objectives of this study were to determine if patien...
32,753,137
Mayo Clin Proc
Smell and Taste Dysfunction in Patients With COVID-19: A Systematic Review and Meta-analysis.
OBJECTIVE: To estimate the prevalence of olfactory and gustatory dysfunctions (OGDs) among patients infected with novel coronavirus disease 2019 (COVID-19). METHODS: A systematic review was conducted by searching MEDLINE, EMBASE, and the preprint server MedRxiv from their inception until May 11, 2020, using the terms a...
Journal Article;Meta-Analysis;Systematic Review
Agyeman, Akosua Adom;Chin, Ken L;Landersdorfer, Cornelia B;Liew, Danny;Ofori-Asenso, Richard
10.1016/j.mayocp.2020.05.030
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Smell and Taste Dysfunction in Patients With COVID-19: A Systematic Review and Meta-analysis. [Abstract]: OBJECTIVE: To estimate the prevalence of olfactory and gustatory dysfunctions (OGDs) among patients infected with novel coronavirus disease 2019 (COVID-19). METHODS: A systematic review was conducted by se...
32,747,875
Am J Med Case Rep
A Systematic Review of COVID-19 and Myocarditis.
Background: The COVID-19 infection which emerged in December 2019, is caused by the virus SARS-CoV-2. Infection with this virus can lead to severe respiratory illness, however, myocarditis has also been reported. The purpose of this study is to identify the clinical features of myocarditis in COVID-19 patients. Methods...
covid-19;myocarditis;sars-cov-2;cardiac mri;echocardiogram;electrocardiography
Journal Article
Kariyanna, Pramod Theetha;Sutarjono, Bayu;Grewal, Ekjot;Singh, Kamal Preet;Aurora, Lyudmila;Smith, Leanna;Chandrakumar, Harshith Priyan;Jayarangaiah, Apoorva;Goldman, Sarah A;Salifu, Moro O;McFarlane, Isabel M
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: A Systematic Review of COVID-19 and Myocarditis. [Abstract]: Background: The COVID-19 infection which emerged in December 2019, is caused by the virus SARS-CoV-2. Infection with this virus can lead to severe respiratory illness, however, myocarditis has also been reported. The purpose of this study is to ident...
32,596,894
Hastings Cent Rep
A Strategy to Prevent and Control Zoonoses?
The authors argue that in preventing and controlling the pandemic of Covid-19, we should have taken an offensive or proactive strategy rather than a defensive or reactionary one because the former type of approach can bring about more health benefits and fewer harms than can the latter. The offensive or proactive appro...
covid-19;sars-cov-2;outbreak;spillover;strategy;zoonoses
Journal Article
Lei, Ruipeng;Qiu, Renzong
10.1002/hast.1142
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A Strategy to Prevent and Control Zoonoses? [Abstract]: The authors argue that in preventing and controlling the pandemic of Covid-19, we should have taken an offensive or proactive strategy rather than a defensive or reactionary one because the former type of approach can bring about more health benefits and ...
32,685,080
Radiol Case Rep
Clinical features and chest CT findings of 3 cases of 2019 novel coronavirus (COVID-19) pneumonia.
Since December 2019, a new type of acute respiratory disease caused by the 2019 novel coronavirus (COVID-19) appeared to Wuhan, China. Currently, positive of virus nucleic acid in respiratory or blood samples is the gold standard for the diagnosis of the disease, but the nucleic acid test may be false negative. Chest C...
c-reactive protein;covid-19 pneumonia;fever;ground-glass opacities
Case Reports
Hu, Xiaoyan;Gou, Jie;Guo, Liang
10.1016/j.radcr.2020.06.031
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Clinical features and chest CT findings of 3 cases of 2019 novel coronavirus (COVID-19) pneumonia. [Abstract]: Since December 2019, a new type of acute respiratory disease caused by the 2019 novel coronavirus (COVID-19) appeared to Wuhan, China. Currently, positive of virus nucleic acid in respiratory or blood...
33,014,641
Cureus
A Case Report of Progressive Liver Failure Inappropriate to Decompensated Heart Failure Following Infection With COVID-19.
This article is about a known case of heart failure presented with acute liver failure following a coronavirus disease-2019 (COVID-19) respiratory tract infection. The patient was admitted with encephalopathy and respiratory distress with a positive COVID-19 reverse transcription-polymerase chain reaction (RT-PCR) test...
covid-19;heart failure;liver failure;respiratory failure
Case Reports
Makarem, Jalil;Naghibi, Nikoo;Beigmohammadi, Mohammad Taghi;Foroumandi, Morteza;Mehrpooya, Maryam
10.7759/cureus.10142
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: A Case Report of Progressive Liver Failure Inappropriate to Decompensated Heart Failure Following Infection With COVID-19. [Abstract]: This article is about a known case of heart failure presented with acute liver failure following a coronavirus disease-2019 (COVID-19) respiratory tract infection. The patient ...
32,583,183
Eur Arch Otorhinolaryngol
Ethyl alcohol threshold test: a fast, reliable and affordable olfactory Assessment tool for COVID-19 patients.
OBJECTIVE: COVID-19 patients may present mild symptoms. The identification of paucisymptomatic patients is paramount in order to interrupt the transmission chain of the virus. Olfactory loss could be one of those early symptoms which might help in the diagnosis of COVID-19 patients. In this study, we aim to develop and...
covid-19;olfaction;olfactory impairment;sars-cov-2;sniff test
Journal Article
Calvo-Henriquez, Christian;Maldonado-Alvarado, Byron;Chiesa-Estomba, Carlos;Rivero-Fernandez, Irene;Sanz-Rodriguez, Marta;Villarreal, Ithzel Maria;Rodriguez-Iglesias, Miguel;Marino-Sanchez, Franklin;Rivero-de-Aguilar, Alejandro;Lechien, Jerome R;Martinez-Capoccioni, Gabriel;Saussez, Sven;Capasso, Robson;Karkos, Petros ...
10.1007/s00405-020-06131-3
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Ethyl alcohol threshold test: a fast, reliable and affordable olfactory Assessment tool for COVID-19 patients. [Abstract]: OBJECTIVE: COVID-19 patients may present mild symptoms. The identification of paucisymptomatic patients is paramount in order to interrupt the transmission chain of the virus. Olfactory lo...
32,953,445
Respir Med Case Rep
How the first cases of COVID-19 in 10 countries become infected? a case series.
Recently, a new respiratory infectious disease called COVID-19 has emerged and created a global emergency. It was initially linked to the animal-to-human transmission. However, it is now thought that COVID-19 is spreading through human-to-human transmission mainly via droplets. As there is no definite antiviral therapy...
2019-ncov;covid-19;coronavirus;first cases;infection
Case Reports
Sadeghmoghadam, Leila;Daneshfar, Majid;Sharifi, Farshad;Alizad, Vida
10.1016/j.rmcr.2020.101219
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: How the first cases of COVID-19 in 10 countries become infected? a case series. [Abstract]: Recently, a new respiratory infectious disease called COVID-19 has emerged and created a global emergency. It was initially linked to the animal-to-human transmission. However, it is now thought that COVID-19 is spreadi...
32,741,160
Zhonghua Liu Xing Bing Xue Za Zhi
[Advances on the asymptomatic infection of COVID-19].
The COVID-19 outbreak in China has been gradually controlled. At present, the management and risk assessment of asymptomatic infected cases has become an urgent problem to be addressed. Asymptomatic case is mainly detected by close contact screening, cluster epidemic investigation, infection source tracking investigati...
asymptomatic cases;covid-19;disease management.;mass screening
Journal Article
Gao, W J;Zheng, K;Ke, J;Li, L M
10.3760/cma.j.cn112338-20200404-00514
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: [Advances on the asymptomatic infection of COVID-19]. [Abstract]: The COVID-19 outbreak in China has been gradually controlled. At present, the management and risk assessment of asymptomatic infected cases has become an urgent problem to be addressed. Asymptomatic case is mainly detected by close contact scree...
33,060,199
J Biol Chem
Unusual zwitterionic catalytic site of SARS-CoV-2 main protease revealed by neutron crystallography.
The main protease (3CL M(pro)) from SARS-CoV-2, the etiological agent of COVID-19, is an essential enzyme for viral replication. 3CL M(pro) possesses an unusual catalytic dyad composed of Cys(145) and His(41) residues. A critical question in the field has been what the protonation states of the ionizable residues in th...
3cl mpro;3cl main protease;sars-cov-2;sars-cov-2 3cl main protease;x-ray crystallography;drug design;enzyme mechanism;hydrogen bond;joint neutron;neutron diffraction;protonation state;room temperature;viral protease
Journal Article;Research Support, Non-U.S. Gov't
Kneller, Daniel W;Phillips, Gwyndalyn;Weiss, Kevin L;Pant, Swati;Zhang, Qiu;O'Neill, Hugh M;Coates, Leighton;Kovalevsky, Andrey
10.1074/jbc.AC120.016154
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Unusual zwitterionic catalytic site of SARS-CoV-2 main protease revealed by neutron crystallography. [Abstract]: The main protease (3CL M(pro)) from SARS-CoV-2, the etiological agent of COVID-19, is an essential enzyme for viral replication. 3CL M(pro) possesses an unusual catalytic dyad composed of Cys(145) a...
33,030,513
Br Med Bull
Narrative review of non-pharmaceutical behavioural measures for the prevention of COVID-19 (SARS-CoV-2) based on the Health-EDRM framework.
INTRODUCTION: Non-pharmaceutical measures to facilitate a response to the COVID-19 pandemic, a disease caused by novel coronavirus SARS-CoV-2, are urgently needed. Using the World Health Organization (WHO) health emergency and disaster risk management (health-EDRM) framework, behavioural measures for droplet-borne comm...
covid-19;sars-cov-2;behavioural measures;biological hazards;coronavirus;droplet-borne;health-edrm;non-pharmaceutical;pandemic;primary prevention
Journal Article;Research Support, Non-U.S. Gov't;Review
Yang Chan, Emily Ying;Shahzada, Tayyab Salim;Sham, Tiffany Sze Tung;Dubois, Caroline;Huang, Zhe;Liu, Sida;Ho, Janice Ying-En;Hung, Kevin K C;Kwok, Kin On;Shaw, Rajib
10.1093/bmb/ldaa030
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Narrative review of non-pharmaceutical behavioural measures for the prevention of COVID-19 (SARS-CoV-2) based on the Health-EDRM framework. [Abstract]: INTRODUCTION: Non-pharmaceutical measures to facilitate a response to the COVID-19 pandemic, a disease caused by novel coronavirus SARS-CoV-2, are urgently nee...
32,562,316
FASEB J
A proposed role for the SARS-CoV-2 nucleocapsid protein in the formation and regulation of biomolecular condensates.
To date, the recently discovered SARS-CoV-2 virus has afflicted >6.9 million people worldwide and disrupted the global economy. Development of effective vaccines or treatments for SARS-CoV-2 infection will be aided by a molecular-level understanding of SARS-CoV-2 proteins and their interactions with host cell proteins....
enveloped viruses;liquid-liquid phase separation;low-complexity domain;stress granule;viral capsid
Journal Article
Cascarina, Sean M;Ross, Eric D
10.1096/fj.202001351
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: A proposed role for the SARS-CoV-2 nucleocapsid protein in the formation and regulation of biomolecular condensates. [Abstract]: To date, the recently discovered SARS-CoV-2 virus has afflicted >6.9 million people worldwide and disrupted the global economy. Development of effective vaccines or treatments for SA...
32,319,538
Int J Mol Med
Zinc and respiratory tract infections: Perspectives for COVID19 (Review).
In view of the emerging COVID19 pandemic caused by SARSCoV2 virus, the search for potential protective and therapeutic antiviral strategies is of particular and urgent interest. Zinc is known to modulate antiviral and antibacterial immunity and regulate inflammatory response. Despite the lack of clinical data, certain ...
Journal Article;Review
Skalny, Anatoly V;Rink, Lothar;Ajsuvakova, Olga P;Aschner, Michael;Gritsenko, Viktor A;Alekseenko, Svetlana I;Svistunov, Andrey A;Petrakis, Demetrios;Spandidos, Demetrios A;Aaseth, Jan;Tsatsakis, Aristidis;Tinkov, Alexey A
10.3892/ijmm.2020.4575
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Zinc and respiratory tract infections: Perspectives for COVID19 (Review). [Abstract]: In view of the emerging COVID19 pandemic caused by SARSCoV2 virus, the search for potential protective and therapeutic antiviral strategies is of particular and urgent interest. Zinc is known to modulate antiviral and antibac...
32,871,219
Int J Pharm
An investigation of rhinovirus infection on cellular uptake of poly (glycerol-adipate) nanoparticles.
Viral infections represent 44% of newly emerging infections, and as is shown by the COVID-19 outbreak constitute a major risk to human health and wellbeing. Although there are many efficient antiviral agents, they still have drawbacks such as development of virus resistance and accumulation within off-target organs. En...
hela and beas-2b cells;nanoparticle uptake;poly (glycerol-adipate);polymer nanoparticles;virus infection
Journal Article
Abo-Zeid, Yasmin;Williams, Gareth R;Touabi, Lila;McLean, Gary R
10.1016/j.ijpharm.2020.119826
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: An investigation of rhinovirus infection on cellular uptake of poly (glycerol-adipate) nanoparticles. [Abstract]: Viral infections represent 44% of newly emerging infections, and as is shown by the COVID-19 outbreak constitute a major risk to human health and wellbeing. Although there are many efficient antivi...
32,552,415
Br J Biomed Sci
Atypical and novel presentations of Coronavirus Disease 2019: a case series of three children.
Typical presentations of Coronavirus Disease 2019 (Covid-19) including respiratory symptoms (cough, respiratory distress and hypoxia), fever and dyspnoea are considered main symptoms in adults, but atypical presentation in children could be a diagnostic challenge. We report three children whose initial presentation was...
covid-19;appendicitis;flank tenderness;gastrointestinal symptoms;mesenteric adenitis
Case Reports;Journal Article
Ekbatani, M S;Hassani, S A;Tahernia, L;Yaghmaei, B;Mahmoudi, S;Navaeian, A;Rostamyan, M;Zamani, F;Mamishi, S
10.1080/09674845.2020.1785102
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Atypical and novel presentations of Coronavirus Disease 2019: a case series of three children. [Abstract]: Typical presentations of Coronavirus Disease 2019 (Covid-19) including respiratory symptoms (cough, respiratory distress and hypoxia), fever and dyspnoea are considered main symptoms in adults, but atypic...
33,061,805
Int J Biol Sci
Update of the current knowledge on genetics, evolution, immunopathogenesis, and transmission for coronavirus disease 19 (COVID-19).
In December 2019, an acute respiratory disease caused by novel species of coronavirus (SARS-CoV-2), emerged in China and has spread throughout the world. On 11(th) March 2020, the World Health Organization (WHO) officially declared coronavirus disease 19 (COVID-19) a pandemic, severe coronavirus-mediated human disease....
covid-19;immunity;sars-cov-2;sars-cov-2 genomics;evolution;genetic variation;transmission
Journal Article;Review
Tizaoui, Kalthoum;Zidi, Ines;Lee, Keum Hwa;Ghayda, Ramy Abou;Hong, Sung Hwi;Li, Han;Smith, Lee;Koyanagi, Ai;Jacob, Louis;Kronbichler, Andreas;Shin, Jae Il
10.7150/ijbs.48812
[ 0, 0, 0, 1, 1, 0, 0 ]
[Title]: Update of the current knowledge on genetics, evolution, immunopathogenesis, and transmission for coronavirus disease 19 (COVID-19). [Abstract]: In December 2019, an acute respiratory disease caused by novel species of coronavirus (SARS-CoV-2), emerged in China and has spread throughout the world. On 11(th) Mar...
32,428,385
Br J Health Psychol
Reducing SARS-CoV-2 transmission in the UK: A behavioural science approach to identifying options for increasing adherence to social distancing and shielding vulnerable people.
PURPOSE: To describe and discuss a systematic method for producing a very rapid response (3 days) to a UK government policy question in the context of reducing SARS-CoV-2 transmission. METHODS: A group of behavioural and social scientists advising the UK government on COVID-19 contributed to the analysis and writing of...
behaviour change wheel;covid-19;sars-cov-2;policy;rapid response
Journal Article
Michie, Susan;West, Robert;Rogers, M Brooke;Bonell, Chris;Rubin, G James;Amlot, Richard
10.1111/bjhp.12428
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Reducing SARS-CoV-2 transmission in the UK: A behavioural science approach to identifying options for increasing adherence to social distancing and shielding vulnerable people. [Abstract]: PURPOSE: To describe and discuss a systematic method for producing a very rapid response (3 days) to a UK government polic...
32,770,243
J Pediatric Infect Dis Soc
Intussusception in 2 Children With Severe Acute Respiratory Syndrome Coronavirus-2 Infection.
We note that intussusception was likely associated with severe acute respiratory syndrome coronavirus-2 infection in 2 infants in Wuhan and London. The intussusception was reduced by enemas in Wuhan; the outcome was fatal. The intussusception was not reduced by enemas in London and required surgery; the outcome was fav...
sars-cov-2;case report;gastrointestinal;gut;intussusception
Case Reports;Journal Article
Makrinioti, Heidi;MacDonald, Alexander;Lu, Xiaoxia;Wallace, Susan;Jobson, Mathew;Zhang, Furong;Shao, Jianbo;Bretherton, Jonathan;Mehmood, Tariq;Eyre, Elizabeth;Wong, Adelene;Pakkiri, Lorna;Saxena, Amulya;Wong, Gary
10.1093/jpids/piaa096
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Intussusception in 2 Children With Severe Acute Respiratory Syndrome Coronavirus-2 Infection. [Abstract]: We note that intussusception was likely associated with severe acute respiratory syndrome coronavirus-2 infection in 2 infants in Wuhan and London. The intussusception was reduced by enemas in Wuhan; the o...
33,052,967
PLoS One
Countering misinformation via WhatsApp: Preliminary evidence from the COVID-19 pandemic in Zimbabwe.
We examine how information from trusted social media sources can shape knowledge and behavior when misinformation and mistrust are widespread. In the context of the COVID-19 pandemic in Zimbabwe, we partnered with a trusted civil society organization to randomize the timing of the dissemination of messages aimed at tar...
Journal Article
Bowles, Jeremy;Larreguy, Horacio;Liu, Shelley
10.1371/journal.pone.0240005
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Countering misinformation via WhatsApp: Preliminary evidence from the COVID-19 pandemic in Zimbabwe. [Abstract]: We examine how information from trusted social media sources can shape knowledge and behavior when misinformation and mistrust are widespread. In the context of the COVID-19 pandemic in Zimbabwe, we...
32,834,815
Adv Differ Equ
A mathematical model of COVID-19 using fractional derivative: outbreak in India with dynamics of transmission and control.
Since the first case of 2019 novel coronavirus disease (COVID-19) detected on 30 January, 2020, in India, the number of cases rapidly increased to 3819 cases including 106 deaths as of 5 April, 2020. Taking this into account, in the present work, we have analysed a Bats-Hosts-Reservoir-People transmission fractional-or...
basic reproduction number;caputo-fabrizio derivative;coronavirus;existence and stability;numerical simulations
Journal Article
Shaikh, Amjad Salim;Shaikh, Iqbal Najiroddin;Nisar, Kottakkaran Sooppy
10.1186/s13662-020-02834-3
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: A mathematical model of COVID-19 using fractional derivative: outbreak in India with dynamics of transmission and control. [Abstract]: Since the first case of 2019 novel coronavirus disease (COVID-19) detected on 30 January, 2020, in India, the number of cases rapidly increased to 3819 cases including 106 deat...
32,163,030
Emerg Infect Dis
Indirect Virus Transmission in Cluster of COVID-19 Cases, Wenzhou, China, 2020.
To determine possible modes of virus transmission, we investigated a cluster of coronavirus disease cases associated with a shopping mall in Wenzhou, China. Data indicated that indirect transmission of the causative virus occurred, perhaps resulting from virus contamination of common objects, virus aerosolization in a ...
2019 novel coronavirus disease;covid-19;china;sars-cov-2;wenzhou;aerosolization;cluster;coronavirus;respiratory infections;severe acute respiratory syndrome coronavirus 2;viruses;zoonoses
Journal Article;Research Support, Non-U.S. Gov't
Cai, Jing;Sun, Wenjie;Huang, Jianping;Gamber, Michelle;Wu, Jing;He, Guiqing
10.3201/eid2606.200412
[ 0, 0, 0, 0, 1, 0, 0 ]
[Title]: Indirect Virus Transmission in Cluster of COVID-19 Cases, Wenzhou, China, 2020. [Abstract]: To determine possible modes of virus transmission, we investigated a cluster of coronavirus disease cases associated with a shopping mall in Wenzhou, China. Data indicated that indirect transmission of the causative vir...
32,365,703
Int J Environ Res Public Health
Estimation of the Excess COVID-19 Cases in Seoul, South Korea by the Students Arriving from China.
Background: In March 2020, overall, 37,000 international students from China, a country at risk of the 2019-novel coronavirus (COVID-19) infection has arrived in Seoul, South Korea. Individuals from the country at risk of COVID-19 infection have been included in the Korean home-quarantine program, but the efficacy of t...
covid-19;korea;compliance;coronavirus;quarantine;simulation
Journal Article;Research Support, Non-U.S. Gov't
Ryu, Sukhyun;Ali, Sheikh Taslim;Lim, Jun-Sik;Chun, Byung Chul
10.3390/ijerph17093113
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Estimation of the Excess COVID-19 Cases in Seoul, South Korea by the Students Arriving from China. [Abstract]: Background: In March 2020, overall, 37,000 international students from China, a country at risk of the 2019-novel coronavirus (COVID-19) infection has arrived in Seoul, South Korea. Individuals from t...
32,864,911
J Korean Med Sci
The Importance of Mandatory COVID-19 Diagnostic Testing Prior to Release from Quarantine.
A 14-day quarantine is implemented in many countries in response to the coronavirus disease pandemic. Korea implemented a mandatory quarantine for those who had close contact with infected patients and those returning from abroad. The present study explored the implications of mandatory coronavirus disease 2019 testing...
contact-tracing;coronavirus;diagnosis;quarantine
Journal Article
Jung, Jaehun;Jang, Hanaram;Kim, Hye Kyung;Kim, Jieun;Kim, Arim;Ko, Kwang Pil
10.3346/jkms.2020.35.e314
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: The Importance of Mandatory COVID-19 Diagnostic Testing Prior to Release from Quarantine. [Abstract]: A 14-day quarantine is implemented in many countries in response to the coronavirus disease pandemic. Korea implemented a mandatory quarantine for those who had close contact with infected patients and those r...
32,518,475
Chaos Solitons Fractals
The resumption of sports competitions after COVID-19 lockdown: The case of the Spanish football league.
In this work, we present a stochastic discrete-time SEIR Susceptible-Exposed-Infectious-Recoveredmodel adapted to describe the propagation of COVID-19 during a football tournament. Specifically, we are concerned about the re-start of the Spanish national football league, La Liga, which is currently -May 2020- stopped w...
covid-19;epidemics;seir;sports
Journal Article
Buldu, Javier M;Antequera, Daniel R;Aguirre, Jacobo
10.1016/j.chaos.2020.109964
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The resumption of sports competitions after COVID-19 lockdown: The case of the Spanish football league. [Abstract]: In this work, we present a stochastic discrete-time SEIR Susceptible-Exposed-Infectious-Recoveredmodel adapted to describe the propagation of COVID-19 during a football tournament. Specifically, ...
32,756,480
Int J Mol Sci
COVID-19: The Immune Responses and Clinical Therapy Candidates.
The pandemic of coronavirus disease 2019 (COVID-19), with rising numbers of patients worldwide, presents an urgent need for effective treatments. To date, there are no therapies or vaccines that are proven to be effective against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Several potential candidates...
covid-19;mers-cov;sars-cov;sars-cov-2;adjunctive therapy;anti-parasite;anti-viral;clinical trial;immunotherapy;molecular immune response
Journal Article;Review
Zhand, Sareh;Saghaeian Jazi, Marie;Mohammadi, Saeed;Tarighati Rasekhi, Roozbeh;Rostamian, Ghassem;Kalani, Mohammad Reza;Rostamian, Aida;George, Jacob;Douglas, Mark W
10.3390/ijms21155559
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: COVID-19: The Immune Responses and Clinical Therapy Candidates. [Abstract]: The pandemic of coronavirus disease 2019 (COVID-19), with rising numbers of patients worldwide, presents an urgent need for effective treatments. To date, there are no therapies or vaccines that are proven to be effective against sever...
32,674,217
Oncology (Williston Park)
Telemedicine Use in Oncology Practices.
The coronavirus disease 2019 (COVID-19) pandemic has rapidly spread all over the world in the past several months. No effective treatment for COVID-19 has been established. High transmissibility and considerable mortality rates have forced many national governments to implement quarantine measures. Many patients with c...
Journal Article
Baum, Neil H
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Telemedicine Use in Oncology Practices. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic has rapidly spread all over the world in the past several months. No effective treatment for COVID-19 has been established. High transmissibility and considerable mortality rates have forced many national gover...
32,721,782
Am J Emerg Med
Vehicle related injury patterns during the COVID-19 pandemic: What has changed?
BACKGROUND: Following the emergence of the COVID-19 pandemic, normal daily life in the United States (US) has changed dramatically. As the US population shifts to practice social distancing, there are undoubtedly changes in the pattern of traumatic injuries presenting to Emergency Departments across the US. This analys...
covid19;social distancing;traffic vehicle collisions;traffic vehicle injuries
Journal Article;Multicenter Study
Sutherland, Mason;McKenney, Mark;Elkbuli, Adel
10.1016/j.ajem.2020.06.006
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Vehicle related injury patterns during the COVID-19 pandemic: What has changed? [Abstract]: BACKGROUND: Following the emergence of the COVID-19 pandemic, normal daily life in the United States (US) has changed dramatically. As the US population shifts to practice social distancing, there are undoubtedly change...
32,734,777
Expert Rev Respir Med
Mortality in COVID-19 patients with acute respiratory distress syndrome and corticosteroids use: a systematic review and meta-analysis.
OBJECTIVES: The acute respiratory distress syndrome (ARDS) secondary to viral pneumonitis is one of the main causes of high mortality in patients with COVID-19 (novel coronavirus disease 2019). We systematically reviewed mortality in COVID-19 patients with ARDS and the potential role of systemic corticosteroids in COVI...
acute respiratory distress syndrome;coronavirus disease 2019;corticosteroids;mortality
Journal Article;Meta-Analysis;Systematic Review
Hasan, Syed Shahzad;Capstick, Toby;Ahmed, Raees;Kow, Chia Siang;Mazhar, Faizan;Merchant, Hamid A;Zaidi, Syed Tabish Razi
10.1080/17476348.2020.1804365
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Mortality in COVID-19 patients with acute respiratory distress syndrome and corticosteroids use: a systematic review and meta-analysis. [Abstract]: OBJECTIVES: The acute respiratory distress syndrome (ARDS) secondary to viral pneumonitis is one of the main causes of high mortality in patients with COVID-19 (no...
32,523,926
Eur J Case Rep Intern Med
Stress Cardiomyopathy in COVID-19 Disease.
Patients affected by COVID-19 pneumonia may develop stress cardiomyopathy, also known as Takotsubo syndrome (TTS), at different stages during the disease and with different degrees of left ventricular dysfunction. We describe three cases of TTS in COVID-19-positive patients with different clinical presentations and out...
covid-19;takotsubo syndrome;cardiomyopathy
Journal Article
Pasqualetto, Maria Cristina;Secco, Eleonora;Nizzetto, Manuele;Scevola, Moreno;Altafini, Lorella;Cester, Alberto;Rigo, Fausto
10.12890/2020_001718
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Stress Cardiomyopathy in COVID-19 Disease. [Abstract]: Patients affected by COVID-19 pneumonia may develop stress cardiomyopathy, also known as Takotsubo syndrome (TTS), at different stages during the disease and with different degrees of left ventricular dysfunction. We describe three cases of TTS in COVID-19...
32,703,737
Disabil Health J
Telemedicine barriers and challenges for persons with disabilities: COVID-19 and beyond.
The COVID-19 pandemic has forced a rapid adoption of telemedicine over traditional in-person visits due to social restrictions. While telemedicine improves access and reduces barriers to healthcare access for many, several barriers and challenges remain for persons with disabilities, and novel challenges have been expo...
disability studies;health legislation;health services accessibility;telemedicine;telerehabilitation
Journal Article
Annaswamy, Thiru M;Verduzco-Gutierrez, Monica;Frieden, Lex
10.1016/j.dhjo.2020.100973
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Telemedicine barriers and challenges for persons with disabilities: COVID-19 and beyond. [Abstract]: The COVID-19 pandemic has forced a rapid adoption of telemedicine over traditional in-person visits due to social restrictions. While telemedicine improves access and reduces barriers to healthcare access for m...
32,969,089
Public Health Nurs
Development of a COVID-19 alternate care site from ground zero: A nursing perspective.
The novel coronavirus disease SARS-CoV-2 (COVID-19) outbreak rapidly generated an unprecedented global, national, and state public health crisis with the need to rapidly develop alternate care sites (ACS) to care for COVID-19 patients within an overburdened health care system. A hospital care model ACS to increase the ...
covid-19;alternate care site;leadership;nursing;pandemic;public health
Journal Article
Stewart, Terri;Day, Sara W;Russell, Jennifer;Wilbanks, Cory;Likes, Wendy;Webb, Sherry;Haushalter, Alisa;Cashion, Ann K
10.1111/phn.12812
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Development of a COVID-19 alternate care site from ground zero: A nursing perspective. [Abstract]: The novel coronavirus disease SARS-CoV-2 (COVID-19) outbreak rapidly generated an unprecedented global, national, and state public health crisis with the need to rapidly develop alternate care sites (ACS) to care...
32,379,077
Am J Forensic Med Pathol
COVID-19: Postmortem Diagnostic and Biosafety Considerations.
As a result of the 2019 novel human coronavirus (COVID-19) global spread, medical examiner/coroner offices will inevitably encounter increased numbers of COVID-19-infected decedents at autopsy. While in some cases a history of fever and/or respiratory distress (eg, cough or shortness of breath) may suggest the diagnosi...
Case Reports;Journal Article
Lacy, J Matthew;Brooks, Erin G;Akers, Joshua;Armstrong, Danielle;Decker, Lauren;Gonzalez, Adam;Humphrey, William;Mayer, Romana;Miller, Matthew;Perez, Catherine;Arango, Jose Antonio Ruiz;Sathyavagiswaran, Lakshmanan;Stroh, Wendy;Utley, Suzanne
10.1097/PAF.0000000000000567
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19: Postmortem Diagnostic and Biosafety Considerations. [Abstract]: As a result of the 2019 novel human coronavirus (COVID-19) global spread, medical examiner/coroner offices will inevitably encounter increased numbers of COVID-19-infected decedents at autopsy. While in some cases a history of fever and/...
32,694,244
Nephron
The Combined Use of Tocilizumab and Hemoadsorption in a Patient with SARS-COV-2-19-Associated Pneumonia: A Case Report.
The SARS-COV-2-19-associated respiratory involvement is caused by the massive release of inflammatory cytokines ultimately leading to interstitial pneumonia and acute respiratory distress syndrome (ARDS). In the absence of an effective antiviral treatment, a reasonable causal approach could be constituted by the neutra...
c-reactive protein.;cytosorb;interleukin 6;sars-cov-2-19;tocilizumab
Case Reports
Berlot, Giorgio;Tomasini, Ariella;Roman Pognuz, Erik;Randino, Anna;Chiella, Fabrizio;La Fata, Cristina;Piva, Marco;Amato, Paola;di Maso, Vittorio;Bianco, Francesco;Gerini, Ugo;Tomietto, Paola;Trenti, Tommaso
10.1159/000509738
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: The Combined Use of Tocilizumab and Hemoadsorption in a Patient with SARS-COV-2-19-Associated Pneumonia: A Case Report. [Abstract]: The SARS-COV-2-19-associated respiratory involvement is caused by the massive release of inflammatory cytokines ultimately leading to interstitial pneumonia and acute respiratory ...
32,698,192
Nature
Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike.
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic continues, with devasting consequences for human lives and the global economy(1,2). The discovery and development of virus-neutralizing monoclonal antibodies could be one approach to treat or prevent infection by this coronavirus. Here we report ...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Liu, Lihong;Wang, Pengfei;Nair, Manoj S;Yu, Jian;Rapp, Micah;Wang, Qian;Luo, Yang;Chan, Jasper F-W;Sahi, Vincent;Figueroa, Amir;Guo, Xinzheng V;Cerutti, Gabriele;Bimela, Jude;Gorman, Jason;Zhou, Tongqing;Chen, Zhiwei;Yuen, Kwok-Yung;Kwong, Peter D;Sodroski, Joseph G;Yin, Michael T;Sheng, Zizhang;Huang, Yaoxing;Shapiro,...
10.1038/s41586-020-2571-7
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike. [Abstract]: The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic continues, with devasting consequences for human lives and the global economy(1,2). The discovery and development of virus-neutralizing monoclonal ...
32,518,105
Clin Med (Lond)
Rehabilitation after COVID-19: an evidence-based approach.
After severe COVID-19 disease, many patients will experience a variety of problems with normal functioning and will require rehabilitation services to overcome these problems. The principles of and evidence on rehabilitation will allow an effective response. These include a simple screening process; use of a multidisci...
covid-19;evidence;rehabilitation;service reconfiguration
Journal Article
Wade, Derick T
10.7861/clinmed.2020-0353
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Rehabilitation after COVID-19: an evidence-based approach. [Abstract]: After severe COVID-19 disease, many patients will experience a variety of problems with normal functioning and will require rehabilitation services to overcome these problems. The principles of and evidence on rehabilitation will allow an e...
32,414,594
J Thorac Cardiovasc Surg
Clinical course of coronavirus disease 2019 in 11 patients after thoracic surgery and challenges in diagnosis.
OBJECTIVES: To illustrate the clinical course and difficulties in early diagnosis of coronavirus disease 2019 (COVID-19) in patients after thoracic surgery. METHODS: We retrospectively analyzed the clinical course of the first 11 patients diagnosed with COVID-19 after thoracic surgery in early January 2020. Postoperati...
covid-19;sars-cov-2;esophageal cancer;lung cancer;postoperative;surgery
Journal Article
Peng, Shu;Huang, Liu;Zhao, Bo;Zhou, Shuchang;Braithwaite, Irene;Zhang, Ni;Fu, Xiangning
10.1016/j.jtcvs.2020.04.005
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical course of coronavirus disease 2019 in 11 patients after thoracic surgery and challenges in diagnosis. [Abstract]: OBJECTIVES: To illustrate the clinical course and difficulties in early diagnosis of coronavirus disease 2019 (COVID-19) in patients after thoracic surgery. METHODS: We retrospectively ana...
32,396,143
Rom J Intern Med
Clinical and laboratory findings from patients with COVID-19 pneumonia in Babol North of Iran: a retrospective cohort study.
BACKGROUND: In December 2019, China has experienced an outbreak of novel coronavirus disease 2019 (COVID-19). Coronavirus has now spread to all of the continents. We aimed to consider clinical characteristics, laboratory data of COVID-19 that provided more information for the research of this novel virus. METHODS: We p...
c-reactive protein;covid-19;elderly;leukocyte count;lymphopenia;mortality;pneumonia
Journal Article
Javanian, Mostafa;Bayani, Masomeh;Shokri, Mehran;Sadeghi-Haddad-Zavareh, Mahmoud;Babazadeh, Arefeh;Yeganeh, Babak;Mohseni, Sima;Mehraeen, Rahele;Sepidarkish, Mahdi;Bijani, Ali;Rostami, Ali;Shahbazi, Mehdi;Tabari, Afrooz Monadi;Shabani, Asieh;Masrour-Roudsari, Jila;Hasanpour, Amir Hossein;Gholinejad, Hossein Emam;Ghorba...
10.2478/rjim-2020-0013
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical and laboratory findings from patients with COVID-19 pneumonia in Babol North of Iran: a retrospective cohort study. [Abstract]: BACKGROUND: In December 2019, China has experienced an outbreak of novel coronavirus disease 2019 (COVID-19). Coronavirus has now spread to all of the continents. We aimed to...
32,761,993
Hepatol Res
Longitudinal changes of liver function and hepatitis B reactivation in COVID-19 patients with pre-existing chronic hepatitis B virus infection.
AIM: With the current coronavirus disease (COVID-19) pandemic and high endemic levels of chronic hepatitis B virus (HBV) infection worldwide, it is urgent to investigate liver function changes of COVID-19 patients with chronic HBV infection, and how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection...
covid-19;hbv;hepatitis b reactivation;liver function
Journal Article
Liu, Jiaye;Wang, Tingyan;Cai, Qingxian;Sun, Liqin;Huang, Deliang;Zhou, Guangde;He, Qing;Wang, Fu-Sheng;Liu, Lei;Chen, Jun
10.1111/hepr.13553
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Longitudinal changes of liver function and hepatitis B reactivation in COVID-19 patients with pre-existing chronic hepatitis B virus infection. [Abstract]: AIM: With the current coronavirus disease (COVID-19) pandemic and high endemic levels of chronic hepatitis B virus (HBV) infection worldwide, it is urgent ...
32,539,259
Zhonghua Liu Xing Bing Xue Za Zhi
[Practice and thinking of acute respiratory infection surveillance for the response of emerging respiratory diseases in Shanghai].
Shanghai Municipal Center for Disease Control and Prevention has implemented an active comprehensive surveillance project of acute respiratory infections in adults in Shanghai, including influenza like illness (ILI) and severe acute respiratory infection (SARI). By testing and identifying a variety of respiratory patho...
covid-19;comprehensive surveillance;emerging infectious diseases;influenza-like illness;severe acute respiratory infection
Journal Article
Chen, J;Zheng, Y X;Kong, D C;Wu, H Y;Yuan, Z A;Wu, F
10.3760/cma.j.cn112338-20200421-00616
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Practice and thinking of acute respiratory infection surveillance for the response of emerging respiratory diseases in Shanghai]. [Abstract]: Shanghai Municipal Center for Disease Control and Prevention has implemented an active comprehensive surveillance project of acute respiratory infections in adults in S...
33,007,742
Bioorg Chem
Role of heterocyclic compounds in SARS and SARS CoV-2 pandemic.
Coronaviruses have led to severe emergencies in the world since the outbreak of SARS CoV in 2002, followed by MERS CoV in 2012. SARS CoV-2, the novel pandemic caused by coronaviruses that began in December 2019 in China has led to a total of 24,066,076 confirmed cases and a death toll of 823,572 as reported by World He...
coronaviruses;heterocyclic scaffolds;mers;pandemic;sars cov;sars cov-2
Journal Article;Review
Negi, Meenakshi;Chawla, Pooja A;Faruk, Abdul;Chawla, Viney
10.1016/j.bioorg.2020.104315
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Role of heterocyclic compounds in SARS and SARS CoV-2 pandemic. [Abstract]: Coronaviruses have led to severe emergencies in the world since the outbreak of SARS CoV in 2002, followed by MERS CoV in 2012. SARS CoV-2, the novel pandemic caused by coronaviruses that began in December 2019 in China has led to a to...
32,653,470
Clin Colorectal Cancer
COVID-19 and the Global Impact on Colorectal Practice and Surgery.
BACKGROUND: The novel severe acute respiratory syndrome coronavirus 2 virus that emerged in December 2019 causing coronavirus disease 2019 (COVID-19) has led to the sudden national reorganization of health care systems and changes in the delivery of health care globally. The purpose of our study was to use a survey to ...
colorectal disease;colorectal surgery;guidance;sars-cov-2;survey
Journal Article
Nunoo-Mensah, Joseph W;Rizk, Mariam;Caushaj, Philip F;Giordano, Pasquale;Fortunato, Richard;Dulskas, Audrius;Bugra, Dursun;da Costa Pereira, Joaquim M;Escalante, Ricardo;Koda, Keiji;Samalavicius, Narimantas E;Maeda, Kotaro;Chun, Ho-Kyung
10.1016/j.clcc.2020.05.011
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 and the Global Impact on Colorectal Practice and Surgery. [Abstract]: BACKGROUND: The novel severe acute respiratory syndrome coronavirus 2 virus that emerged in December 2019 causing coronavirus disease 2019 (COVID-19) has led to the sudden national reorganization of health care systems and changes i...
32,300,823
HNO
[Telemedicine in the fight against SARS-COV-2-opportunities and possible applications in otorhinolaryngology : Narrative review].
INTRODUCTION: The COVID-19 pandemic is bringing healthcare systems worldwide to the brink of collapse. One reason for this is the rapidly increasing number of new infections. On the other hand, the high sickness rates of doctors and nurses, particularly in ENT medicine, are aggravating the situation. Telemedicine can b...
covid-19;corona;infection prevention;pandemic;ehealth
Journal Article;Review
Hagge, Daniel;Knopf, Andreas;Hofauer, Benedikt
10.1007/s00106-020-00864-7
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Telemedicine in the fight against SARS-COV-2-opportunities and possible applications in otorhinolaryngology : Narrative review]. [Abstract]: INTRODUCTION: The COVID-19 pandemic is bringing healthcare systems worldwide to the brink of collapse. One reason for this is the rapidly increasing number of new infect...
32,489,711
Aging Dis
Comorbid Chronic Diseases are Strongly Correlated with Disease Severity among COVID-19 Patients: A Systematic Review and Meta-Analysis.
Coronavirus disease 2019 (COVID-19) has resulted in considerable morbidity and mortality worldwide since December 2019. In order to explore the effects of comorbid chronic diseases on clinical outcomes of COVID-19, a search was conducted in PubMed, Ovid MEDLINE, EMBASE, CDC, and NIH databases to April 25, 2020. A total...
cardiovascular diseases;chronic pulmonary disease;coronavirus disease 2019 (covid-19);diabetes;hypertension;meta-analysis
Journal Article;Review
Liu, Hong;Chen, Shiyan;Liu, Min;Nie, Hao;Lu, Hongyun
10.14336/AD.2020.0502
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Comorbid Chronic Diseases are Strongly Correlated with Disease Severity among COVID-19 Patients: A Systematic Review and Meta-Analysis. [Abstract]: Coronavirus disease 2019 (COVID-19) has resulted in considerable morbidity and mortality worldwide since December 2019. In order to explore the effects of comorbid...
32,259,129
Arch Acad Emerg Med
Metronidazole; a Potential Novel Addition to the COVID-19 Treatment Regimen.
Coronavirus disease 2019 or COVID-19 has rapidly emerged as a global pandemic. This viral infection involves the upper respiratory tract and could lead to severe pneumonia with respiratory distress or even death. Certain studies have found higher initial plasma levels of most pro-inflammatory cytokines during the cours...
covid-19;coronavirus disease;cytokines;interleukins;metronidazole
Journal Article
Gharebaghi, Reza;Heidary, Fatemeh;Moradi, Mohammad;Parvizi, Maryam
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Metronidazole; a Potential Novel Addition to the COVID-19 Treatment Regimen. [Abstract]: Coronavirus disease 2019 or COVID-19 has rapidly emerged as a global pandemic. This viral infection involves the upper respiratory tract and could lead to severe pneumonia with respiratory distress or even death. Certain s...
32,769,091
mBio
Rethinking Gain-of-Function Experiments in the Context of the COVID-19 Pandemic.
Proponents of the use of gain-of-function (GOF) experiments with pathogens with pandemic potential (PPP) have argued that such experiments are necessary because they reveal important facets of pathogenesis and can be performed safely. Opponents of GOF experiments with PPP have argued that the risks outweigh the knowled...
biosafety;bioterrorism;policy
Editorial
Imperiale, Michael J;Casadevall, Arturo
10.1128/mBio.01868-20
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Rethinking Gain-of-Function Experiments in the Context of the COVID-19 Pandemic. [Abstract]: Proponents of the use of gain-of-function (GOF) experiments with pathogens with pandemic potential (PPP) have argued that such experiments are necessary because they reveal important facets of pathogenesis and can be p...
32,549,073
Int Braz J Urol
Clinical and Surgical Assistance in Prostate Cancer during the COVID-19 Pandemic: Implementation of assistance protocols.
PURPOSE: Propose an approach of prostate cancer (PCa) patients during COVID-19 pandemic. MATERIAL AND METHODS: We conducted a review of current literature related to surgical and clinical management of patients during COVID-19 crisis paying special attention to oncological ones and especially those suffering from PCa. ...
covid-19 [supplementary concept];pandemics;prostate cancer, familial [supplementary concept]
Journal Article;Review
Sanchez, Lara Rodriguez;Cathelineau, Xavier;Pinto, Alexis M Alva;Borque-Fernando, Angel;Gil, Maria Jesus;Yee, Chi-Hang;Sanchez-Salas, Rafael
10.1590/S1677-5538.IBJU.2020.S106
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Clinical and Surgical Assistance in Prostate Cancer during the COVID-19 Pandemic: Implementation of assistance protocols. [Abstract]: PURPOSE: Propose an approach of prostate cancer (PCa) patients during COVID-19 pandemic. MATERIAL AND METHODS: We conducted a review of current literature related to surgical an...
32,534,210
J Shoulder Elbow Surg
Patient outcomes after humeral fracture surgery during the COVID-19 outbreak in Spain.
BACKGROUND: The global spread of the 2019 novel coronavirus (COVID-19) has profoundly affected the way we conduct our health care practices. The goal of this paper is to report the outcomes of 11 patients who underwent humeral fracture surgery in the first few weeks of the COVID-19 outbreak in Spain. METHODS: This was ...
shoulder;coronavirus;fracture;humerus;pandemic
Journal Article
Garcia-Portabella, Montserrat;Nunez, Jorge H;Batalla, Lledo;Plomer, Martin;Lakhani, Kushal;Massons, Josep
10.1016/j.jse.2020.06.001
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Patient outcomes after humeral fracture surgery during the COVID-19 outbreak in Spain. [Abstract]: BACKGROUND: The global spread of the 2019 novel coronavirus (COVID-19) has profoundly affected the way we conduct our health care practices. The goal of this paper is to report the outcomes of 11 patients who und...
32,860,073
Med Microbiol Immunol
Assessing SARS-CoV-2 RNA levels and lymphocyte/T cell counts in COVID-19 patients revealed initial immune status as a major determinant of disease severity.
The magnitude of SARS-CoV-2 infection, the dynamic changes of immune parameters in patients with the novel coronavirus disease (COVID-19) and their correlation with the disease severity remain unclear. The clinical and laboratory results from 154 confirmed COVID-19 patients were collected. The SARS-CoV-2 RNA levels in ...
covid-19;immune status;sars-cov-2;severity;viral load
Journal Article
Han, Mingfeng;Xu, Mengyuan;Zhang, Yafei;Liu, Zhongping;Li, Shasha;He, Tengfei;Li, Jinsong;Gao, Yong;Liu, Wanjun;Li, Tuantuan;Chen, Zixiang;Huang, Xin;Cheng, Guoling;Wang, Jun;Dittmer, Ulf;Witzke, Oliver;Zou, Guizhou;Li, Xiuyong;Lu, Mengji;Zhang, Zhenhua
10.1007/s00430-020-00693-z
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Assessing SARS-CoV-2 RNA levels and lymphocyte/T cell counts in COVID-19 patients revealed initial immune status as a major determinant of disease severity. [Abstract]: The magnitude of SARS-CoV-2 infection, the dynamic changes of immune parameters in patients with the novel coronavirus disease (COVID-19) and ...
32,835,165
Neurol Res Pract
Guillain-Barre syndrome and SARS-CoV-2.
Since January 2020, after Chinese health authorities identified a new type of coronavirus (SARS-CoV-2), the virus has spread throughout China and consecutively throughout the whole world. The most common symptoms include fever and respiratory tract symptoms. Nevertheless, some patients show less common symptoms such as...
covid-19;guillain-barre syndrome;sars-cov-2
Journal Article
Lampe, Anne;Winschel, Alexander;Lang, Cornelie;Steiner, Thorsten
10.1186/s42466-020-00066-0
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Guillain-Barre syndrome and SARS-CoV-2. [Abstract]: Since January 2020, after Chinese health authorities identified a new type of coronavirus (SARS-CoV-2), the virus has spread throughout China and consecutively throughout the whole world. The most common symptoms include fever and respiratory tract symptoms. ...
32,769,321
Indian J Pathol Microbiol
Guidelines for various laboratory sections in view of COVID-19: Recommendations from the Indian Association of Pathologists and Microbiologists.
Declared as a pandemic by WHO on March 11, 2020, COVID-19 has brought about a dramatic change in the working of different laboratories across the country. Diagnostic laboratories testing different types of samples play a vital role in the treatment management. Irrespective of their size, each laboratory has to follow s...
biosafety;covid-19;iapm;sars-co-v-2;guidelines;laboratories;mortality
Journal Article;Review
Misra, Vatsala;Agrawal, Ranjan;Kumar, Harendra;Kar, Asaranti;Kini, Usha;Poojary, Aruna;Chakrabarti, Indranil;Rai, Sharada;Singhal, Anika;Shankar, S Vijay;Iyengar, Jayaram N
10.4103/IJPM.IJPM_857_20
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Guidelines for various laboratory sections in view of COVID-19: Recommendations from the Indian Association of Pathologists and Microbiologists. [Abstract]: Declared as a pandemic by WHO on March 11, 2020, COVID-19 has brought about a dramatic change in the working of different laboratories across the country....
33,024,341
Rev Clin Esp
[Performance of the case definition of suspected influenza before and during the COVID-19 pandemic].
OBJECTIVE: This study aimed to evaluate the performance, before and during the COVID-19 pandemic, of the case definition of suspected influenza used in community surveillance in Mexico. METHODS: A cross-sectional analysis of a cohort study took place and cases fulfilling the suspected case criteria (n = 20,511), and wi...
covid-19;influenza;mexico;pandemics;roc curve
Case Reports;English Abstract
Murillo-Zamora, E;Hernandez-Suarez, C
10.1016/j.rce.2020.09.001
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: [Performance of the case definition of suspected influenza before and during the COVID-19 pandemic]. [Abstract]: OBJECTIVE: This study aimed to evaluate the performance, before and during the COVID-19 pandemic, of the case definition of suspected influenza used in community surveillance in Mexico. METHODS: A c...
32,956,925
Diabetes Metab Syndr
Effects of COVID-19 in South African health system and society: An explanatory study.
BACKGROUND AND AIMS: The underestimation of the severity of COVID-19 by the South African government resulted in delayed action against the pandemic. Ever since WHO declared COVID-19 a pandemic preventive action was comprehensively upgraded worldwide. This prompted South African authorities to implement physical distan...
covid-19;case management;effects;health systems;sars-cov-2
Journal Article;Review
Mbunge, Elliot
10.1016/j.dsx.2020.09.016
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Effects of COVID-19 in South African health system and society: An explanatory study. [Abstract]: BACKGROUND AND AIMS: The underestimation of the severity of COVID-19 by the South African government resulted in delayed action against the pandemic. Ever since WHO declared COVID-19 a pandemic preventive action w...
33,024,937
Mayo Clin Proc Innov Qual Outcomes
More Severe Hypercoagulable State in Acute COVID-19 Pneumonia as Compared With Other Pneumonia.
Objective: To conduct a comprehensive evaluation of coagulation profiles-via traditional and whole blood thromboelastometry tests-in coronavirus disease 2019 (COVID-19)-positive vs COVID-19-negative patients admitted to medical wards for acute pneumonia. Patients and Methods: We enrolled all consecutive patients admitt...
cft, clot formation time;covid-19, coronavirus disease 2019;ct, clotting time;mcf, maximum clot firmness;sars-cov-2, severe acute respiratory syndrome coronavirus 2
Journal Article
Spiezia, Luca;Campello, Elena;Cola, Marco;Poletto, Francesco;Cerruti, Lorenzo;Poretto, Anna;Simion, Chiara;Cattelan, Annamaria;Vettor, Roberto;Simioni, Paolo
10.1016/j.mayocpiqo.2020.09.002
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: More Severe Hypercoagulable State in Acute COVID-19 Pneumonia as Compared With Other Pneumonia. [Abstract]: Objective: To conduct a comprehensive evaluation of coagulation profiles-via traditional and whole blood thromboelastometry tests-in coronavirus disease 2019 (COVID-19)-positive vs COVID-19-negative pati...
33,001,431
Int Marit Health
Coronavirus variant COVID-19 pandemic: a report to seafarers.
We report the current situation regarding the COVID-19 pandemic with particular regard to seafarers and with the indications drawn up by the Centro Internazionale Radio Medico (C.I.R.M.) in this regard.
covid-19;acute distress respiratory syndrome;coronavirus;maritime medicine;occupational health
Journal Article;Research Support, Non-U.S. Gov't
Sossai, Paolo;Uguccioni, Silvia;Mela, Giuseppe Sandro;DiCanio, Marzio;Amenta, Francesco
10.5603/IMH.2020.0034
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Coronavirus variant COVID-19 pandemic: a report to seafarers. [Abstract]: We report the current situation regarding the COVID-19 pandemic with particular regard to seafarers and with the indications drawn up by the Centro Internazionale Radio Medico (C.I.R.M.) in this regard. [Keywords]: covid-19;acute distres...
32,301,600
JBRA Assist Reprod
A review of initial data on pregnancy during the COVID-19 outbreak: implications for assisted reproductive treatments.
The current outbreak of the novel 2019 coronavirus disease (COVID-19) started in China in December 2019 and has since spread to several other countries. On March 25, 2020, a total of 375,498 cases had been confirmed globally with 2,201 cases in Brazil, showing the urgency of reacting to this international public health...
covid-19;sars-cov-2;assisted reproduction;pregnancy
Journal Article;Review
Monteleone, Pedro Aa;Nakano, Mayra;Lazar, Victor;Gomes, Alecsandra P;de, Hamilton Martin;Bonetti, Tatiana Cs
10.5935/1518-0557.20200030
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: A review of initial data on pregnancy during the COVID-19 outbreak: implications for assisted reproductive treatments. [Abstract]: The current outbreak of the novel 2019 coronavirus disease (COVID-19) started in China in December 2019 and has since spread to several other countries. On March 25, 2020, a total ...
32,850,560
Front Pediatr
Quantitative Assessment of Parenchymal Involvement Using 3D Lung Model in Adolescent With Covid-19 Interstitial Pneumonia.
Background: Amount of parenchymal involvement in patients with interstitial pneumonia Covid-19 related, seems to be associated with a worse prognosis. Nowadays 3D reconstruction imaging is expanding its role in clinical medical practice. We aimed to use 3D lung reconstruction of a young lady affected by Sars-CoV2 infec...
3d in covid19;3d lung reconstructions;3d modeling in pneumonia;3d parenchima reconstruction;3d quantify in pneumonia;3d rendering in pneumonia
Journal Article
Borro, Luca;Ciliberti, Paolo;Santangelo, Teresa Pia;Magistrelli, Andrea;Campana, Andrea;Carducci, Francesca Calo;Caterina, Marabotto;Toma, Paolo;Secinaro, Aurelio
10.3389/fped.2020.00453
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Quantitative Assessment of Parenchymal Involvement Using 3D Lung Model in Adolescent With Covid-19 Interstitial Pneumonia. [Abstract]: Background: Amount of parenchymal involvement in patients with interstitial pneumonia Covid-19 related, seems to be associated with a worse prognosis. Nowadays 3D reconstructio...
32,538,813
Arch Esp Urol
[Functional urology during COVID-19: Recommendations during de-escalation.]
OBJECTIVES: Due to the COVID-19 Pandemic, all surgical activity that was not life threatening was cancelled , as well as most face-to-face consultations. Currently the beginning of the de-escalation phases that will led us to a new normal, forces us to establish some degree of priority in the interventions as well as i...
covid-19;cirugia;consultas;consultations;functional urology;surgery;urologia funcional
Journal Article
Martinez-Cuenca, Esther;Lopez-Fando, Luis;Adot, Jose Maria;Errando, Carlos;Gomez, Jose Miguel;Gonzalez, Raquel;Madurga, Blanca;MartInez-GarcIa, Roberto;Peri, Lluis;Arlandis, Salvador
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Functional urology during COVID-19: Recommendations during de-escalation.] [Abstract]: OBJECTIVES: Due to the COVID-19 Pandemic, all surgical activity that was not life threatening was cancelled , as well as most face-to-face consultations. Currently the beginning of the de-escalation phases that will led us ...
32,964,930
Eur J Cardiothorac Surg
Regional extracorporeal membrane oxygenation retrieval service during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic: an interdisciplinary team approach to maintain service provision despite increased demand.
OBJECTIVES: Coronavirus disease 2019 is a new contagious disease that has spread rapidly across the world. It is associated with high mortality in those who develop respiratory complications and require admission to intensive care. Extracorporeal membrane oxygenation (ECMO) is a supportive therapy option for selected s...
coronavirus disease 2019;extracorporeal membrane oxygenation;pandemic;retrieval;severe acute respiratory syndrome coronavirus 2;veno-venous-extracorporeal membrane oxygenation
Journal Article
Rafiq, Muhammad U;Valchanov, Kamen;Vuylsteke, Alain;Taghavi, Fouad J;Iyer, Swetha B;Sudarshan, Catherine D;Fowles, Jo-Anne;Anderson, Simon;Govender, Pooveshni;Holmes, Miranda;White, Alexander;Mishra, Abhi;Mwaura, Lucy;Jenkins, David P
10.1093/ejcts/ezaa327
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Regional extracorporeal membrane oxygenation retrieval service during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic: an interdisciplinary team approach to maintain service provision despite increased demand. [Abstract]: OBJECTIVES: Coronavirus disease 2019 is a new contagious diseas...
32,454,103
Exp Mol Pathol
Type I astrocytes and microglia induce a cytokine response in an encephalitic murine coronavirus infection.
The pathogenesis of viral infections involves an immune response by cytokines, causing a deleterious effect on organ function, in addition to tissue destruction due to viral replication. Clinical symptoms and laboratory findings of the human coronavirus disease COVID-19, caused by the novel coronavirus SARS CoV-2, indi...
astrocytes;covid-19;coronavirus;cytokines;microglia;mouse hepatitis virus
Journal Article
Lavi, Ehud;Cong, Lin
10.1016/j.yexmp.2020.104474
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Type I astrocytes and microglia induce a cytokine response in an encephalitic murine coronavirus infection. [Abstract]: The pathogenesis of viral infections involves an immune response by cytokines, causing a deleterious effect on organ function, in addition to tissue destruction due to viral replication. Clin...
32,879,111
Zhong Nan Da Xue Xue Bao Yi Xue Ban
Epidemic features of coronavirus disease 2019 in Henan Province.
OBJECTIVES: To analyze the regional epidemic features of coronavirus disease 2019 (COVID-19) in Henan Province, China. METHODS: According to the data of COVID-19 patients and the resident population at the end of 2018 in Henan Province, statistical description and analysis of epidemiological characteristics of COVID-19...
coronavirus disease 2019;epidemiologic characteristics;incidence rate;population distribution;regional distribution;time distribution
Journal Article
Ma, Qianqian;Li, Chenchen;Zhai, Yunkai;Gao, Jinghong;Zhao, Jie
10.11817/j.issn.1672-7347.2020.200213
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Epidemic features of coronavirus disease 2019 in Henan Province. [Abstract]: OBJECTIVES: To analyze the regional epidemic features of coronavirus disease 2019 (COVID-19) in Henan Province, China. METHODS: According to the data of COVID-19 patients and the resident population at the end of 2018 in Henan Provinc...
32,926,172
Health Lit Res Pract
African American Adherence to COVID-19 Public Health Recommendations.
By mid-May 2020, most of the United States had been under shelter-in-place orders for several weeks to decrease the spread of coronavirus 2019 (COVID-19). As states begin to lift these orders to reopen the economy, the risk of a resurgence of COVID-19 may be related to the public's voluntary adherence to public health ...
Journal Article
Block, Ray Jr;Berg, Arthur;Lennon, Robert P;Miller, Erin L;Nunez-Smith, Marcella
10.3928/24748307-20200707-01
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: African American Adherence to COVID-19 Public Health Recommendations. [Abstract]: By mid-May 2020, most of the United States had been under shelter-in-place orders for several weeks to decrease the spread of coronavirus 2019 (COVID-19). As states begin to lift these orders to reopen the economy, the risk of a ...
32,781,247
Pract Radiat Oncol
Low-Dose Hypofractionated Total Skin Electron Beam Therapy for Adult Cutaneous T-Cell Lymphoma.
PURPOSE: Historically, the standard of care for total skin electron beam therapy (TSEBT) delivered 30 to 36 Gy over 5 to 10 weeks. Given the high risk of relapse, a majority of patients require additional treatments. Therefore, attempts to use a shortened course of TSEBT have been investigated. METHODS AND MATERIALS: W...
Journal Article
Jeans, Elizabeth B;Hu, Yue-Houng;Stish, Bradley J;King, Brian;Davis, Mark;Harmsen, William S;Fruth, Kristin M;Locher, Sarah E;Deufel, Christopher L;Evans, Jaden D;Martenson, James A;Lester, Scott C
10.1016/j.prro.2020.08.001
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Low-Dose Hypofractionated Total Skin Electron Beam Therapy for Adult Cutaneous T-Cell Lymphoma. [Abstract]: PURPOSE: Historically, the standard of care for total skin electron beam therapy (TSEBT) delivered 30 to 36 Gy over 5 to 10 weeks. Given the high risk of relapse, a majority of patients require additiona...
33,022,727
Dtsch Med Wochenschr
[Vaccines for adults: an update].
Vaccination practices in Germany are driven by scientific developments and a complex regulatory environment. Some important developments in 2019/20 are described here: Work-related vaccination recommendations for measles, rubella, and chickenpox have been streamlined and expanded. In addition, measles vaccination or do...
Journal Article
Seybold, Ulrich
10.1055/a-0982-8894
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: [Vaccines for adults: an update]. [Abstract]: Vaccination practices in Germany are driven by scientific developments and a complex regulatory environment. Some important developments in 2019/20 are described here: Work-related vaccination recommendations for measles, rubella, and chickenpox have been streamlin...
32,454,003
Aust J Prim Health
What should primary care look like after the COVID-19 pandemic?
The response to COVID-19 transformed primary care: new telehealth items were added to the Medicare Benefits Schedule, and their use quickly escalated, general practices and community health centres developed new ways of working and patients embraced the changes. As new coronavirus infections plummet and governments con...
Journal Article
Duckett, Stephen
10.1071/PY20095
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: What should primary care look like after the COVID-19 pandemic? [Abstract]: The response to COVID-19 transformed primary care: new telehealth items were added to the Medicare Benefits Schedule, and their use quickly escalated, general practices and community health centres developed new ways of working and pat...
32,840,663
Radiologe
[Emergency and intensive care medicine aspects of COVID-19 infections].
CLINICAL ISSUE: The COVID 19 pandemic led to a profound adaptation of the German healthcare system in preparation of a massive increase of SARS-CoV-2-associated diseases. While general practitioners care for COVID patients who are less severely ill, hospitals are focused on the care of severely ill COVID-19 patients. S...
covid-19 pneumonia;organ failure;pandemic;respiration, artificial;sars-cov2
Journal Article;Review
Dodt, C;Schneider, N
10.1007/s00117-020-00742-x
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: [Emergency and intensive care medicine aspects of COVID-19 infections]. [Abstract]: CLINICAL ISSUE: The COVID 19 pandemic led to a profound adaptation of the German healthcare system in preparation of a massive increase of SARS-CoV-2-associated diseases. While general practitioners care for COVID patients who ...
32,858,727
J Ambul Care Manage
Pandemic Notes From a Maine Direct Primary Care Practice.
The effects of coronavirus disease-2019 (COVID-19) pandemic fear and its economic impact in rural primary care are still being felt, as they have affected demand for office visits and how we deliver care. Our finances and our ability to sustainably deliver this care, however, have not yet changed significantly due to t...
Journal Article
Pierce, Brian R;Pierce, Claire
10.1097/JAC.0000000000000347
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Pandemic Notes From a Maine Direct Primary Care Practice. [Abstract]: The effects of coronavirus disease-2019 (COVID-19) pandemic fear and its economic impact in rural primary care are still being felt, as they have affected demand for office visits and how we deliver care. Our finances and our ability to sust...
32,363,226
Radiol Infect Dis
A mild type of childhood Covid-19 - A case report.
This case is about a 9-year-old child diagnosed with COVID-19, with a history of epidemiology; SARS-CoV-2 nucleic acids testing was positive, while chest CT examination was negative. The clinical classification was light. Nonetheless, isolation measures should still be taken to avoid infecting others.
covid-19;ct;child;mild;sars-cov-2
Case Reports
Yin, Xiaoping;Dong, Li;Zhang, Yu;Bian, Weilin;Li, Hongjun
10.1016/j.jrid.2020.03.004
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: A mild type of childhood Covid-19 - A case report. [Abstract]: This case is about a 9-year-old child diagnosed with COVID-19, with a history of epidemiology; SARS-CoV-2 nucleic acids testing was positive, while chest CT examination was negative. The clinical classification was light. Nonetheless, isolation mea...
32,771,032
Trials
Pakistan Randomized and Observational Trial to Evaluate Coronavirus Treatment (PROTECT) of Hydroxychloroquine, Oseltamivir and Azithromycin to treat newly diagnosed patients with COVID-19 infection who have no comorbidities like diabetes mellitus: A structured summary of a study protocol for a randomized controlled tri...
OBJECTIVES: To evaluate the effectiveness of Hydroxychloroquine Phosphate/Sulfate (200 mg orally 8 hourly thrice a day for 5 days), versus oseltamivir (75 mg orally twice a day for 5 days), and versus Azithromycin (500 mg orally daily on day 1, followed by 250 mg orally twice a day on days 2-5) alone and in combination...
azithromycin;covid-19;hydroxychloroquine;oseltamivir;randomised controlled trial;sars-cov-2;adaptive;multi-center;protocol;randomization
Clinical Trial Protocol;Letter;Multicenter Study;Observational Study;Randomized Controlled Trial
Akram, Javed;Azhar, Shehnoor;Shahzad, Muhammad;Latif, Waqas;Khan, Khalid Saeed
10.1186/s13063-020-04616-4
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Pakistan Randomized and Observational Trial to Evaluate Coronavirus Treatment (PROTECT) of Hydroxychloroquine, Oseltamivir and Azithromycin to treat newly diagnosed patients with COVID-19 infection who have no comorbidities like diabetes mellitus: A structured summary of a study protocol for a randomized contr...
32,639,216
J Perioper Pract
COVID-19 preparedness and response at a large UK major trauma operating theatres department.
This article aims to describe the early experience of a large major trauma operating theatres department in the East of England during the outbreak of the coronavirus disease 2019 (COVID-19) pandemic. To date and to our knowledge, a small amount of reports describing a surgical department's response to this unprecedent...
theatre utilisation and staffing / teamwork and communication / service improvement / risk management / leadership / infection control / operating theatre
Journal Article;Review
Britton, Carolina R;Hayman, Gareth;Macfarlane, Claudia;Alawattegama, Hemantha;Ballecer, Jasper;Stroud, Nicola;Wallace, Alexander
10.1177/1750458920934406
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 preparedness and response at a large UK major trauma operating theatres department. [Abstract]: This article aims to describe the early experience of a large major trauma operating theatres department in the East of England during the outbreak of the coronavirus disease 2019 (COVID-19) pandemic. To da...
32,711,848
Transplant Proc
Identifying a Kidney Transplant Recipient COVID Phenotype to Aid Test Utilization in the Setting of Limited Testing Availability-Does One Exist?
The high morbidity and mortality of COVID-19 in immunocompetent patients raises significant concern for immunosuppressed kidney transplant recipients (KTRs). This level of concern, both on the part of the KTRs and transplant professionals, is heightened by a lack of prior knowledge on how Severe Acute Respiratory Syndr...
Journal Article
Virmani, Sarthak;Gleeson, Shana E;Girone, Gianna F;Malhotra, Divyanshu;Cohen, Elizabeth A;Klarman, Sharon E;Asch, William S
10.1016/j.transproceed.2020.05.033
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Identifying a Kidney Transplant Recipient COVID Phenotype to Aid Test Utilization in the Setting of Limited Testing Availability-Does One Exist? [Abstract]: The high morbidity and mortality of COVID-19 in immunocompetent patients raises significant concern for immunosuppressed kidney transplant recipients (KTR...
32,998,156
Nature
The major genetic risk factor for severe COVID-19 is inherited from Neanderthals.
A recent genetic association study(1) identified a gene cluster on chromosome 3 as a risk locus for respiratory failure after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A separate study (COVID-19 Host Genetics Initiative)(2) comprising 3,199 hospitalized patients with coronavirus disea...
Journal Article;Research Support, Non-U.S. Gov't
Zeberg, Hugo;Paabo, Svante
10.1038/s41586-020-2818-3
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: The major genetic risk factor for severe COVID-19 is inherited from Neanderthals. [Abstract]: A recent genetic association study(1) identified a gene cluster on chromosome 3 as a risk locus for respiratory failure after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A separate stu...
33,072,869
Med Clin (Engl Ed)
Therapeutic agents tested in 238 COVID-19 hospitalized patients and their relationship with mortality.
Background and objectives: In the last months great efforts have been developed to evaluate the more efficient therapeutic agents in the management of patients with COVID-19. Currently, no specific drug combination has consistently demonstrated an association with mortality. The aim of this study was to assess the patt...
covid;hospitalized;mortality;sars-cov-2;treatments
Journal Article
Rivera-Izquierdo, Mario;Valero-Ubierna, Maria Del Carmen;R-delAmo, Juan Luis;Fernandez-Garcia, Miguel Angel;Martinez-Diz, Silvia;Tahery-Mahmoud, Arezu;Rodriguez-Camacho, Marta;Gamiz-Molina, Ana Belen;Barba-Gyengo, Nicolas;Gamez-Baeza, Pablo;Cabrero-Rodriguez, Celia;Guirado-Ruiz, Pedro Antonio;Martin-Romero, Divina Tati...
10.1016/j.medcle.2020.06.024
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Therapeutic agents tested in 238 COVID-19 hospitalized patients and their relationship with mortality. [Abstract]: Background and objectives: In the last months great efforts have been developed to evaluate the more efficient therapeutic agents in the management of patients with COVID-19. Currently, no specifi...
32,589,931
Ann Vasc Surg
A Case of Covid-19 Patient with Acute Limb Ischemia and Heparin Resistance.
Heparin resistance is an uncommon phenomenon defined as the need for high-dose unfractionated heparin (UFH) of more than 35,000 IU/day to achieve the target activated partial-thromboplastin time ratio or the failure to achieve the desired activated clotting time after a full UFH dose. This rare phenomenon is being more...
Case Reports
Baccellieri, Domenico;Bilman, Victor;Apruzzi, Luca;Monaco, Fabrizio;D'Angelo, Armando;Loschi, Diletta;Melissano, Germano;Chiesa, Roberto
10.1016/j.avsg.2020.06.046
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: A Case of Covid-19 Patient with Acute Limb Ischemia and Heparin Resistance. [Abstract]: Heparin resistance is an uncommon phenomenon defined as the need for high-dose unfractionated heparin (UFH) of more than 35,000 IU/day to achieve the target activated partial-thromboplastin time ratio or the failure to achi...
32,833,687
J Clin Invest
SARS-CoV-2-specific T cell responses and correlations with COVID-19 patient predisposition.
Coronavirus disease 2019 (COVID-19) has emerged as a global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). So far, viral targets of cellular immunity and factors determining successful mounting of T cell responses are poorly defined. We therefore analyzed cellular responses to membrane...
antigen;covid-19;t cells
Clinical Trial;Journal Article
Sattler, Arne;Angermair, Stefan;Stockmann, Helena;Heim, Katrin Moira;Khadzhynov, Dmytro;Treskatsch, Sascha;Halleck, Fabian;Kreis, Martin E;Kotsch, Katja
10.1172/JCI140965
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: SARS-CoV-2-specific T cell responses and correlations with COVID-19 patient predisposition. [Abstract]: Coronavirus disease 2019 (COVID-19) has emerged as a global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). So far, viral targets of cellular immunity and factors determining...
32,130,047
AJR Am J Roentgenol
Deja Vu or Jamais Vu? How the Severe Acute Respiratory Syndrome Experience Influenced a Singapore Radiology Department's Response to the Coronavirus Disease (COVID-19) Epidemic.
OBJECTIVE. This article shares the ground operational perspective of how a tertiary hospital radiology department in Singapore is responding to the coronavirus disease (COVID-19) epidemic. This same department was also deeply impacted by the severe acute respiratory syndrome (SARS) outbreak in 2003. CONCLUSION. Though ...
covid-19;sars;infection control;novel coronavirus;outbreak;radiology operations
Journal Article
Cheng, Lionel Tim-Ee;Chan, Lai Peng;Tan, Ban Hock;Chen, Robert Chun;Tay, Kiang Hiong;Ling, Moi Lin;Tan, Bien Soo
10.2214/AJR.20.22927
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Deja Vu or Jamais Vu? How the Severe Acute Respiratory Syndrome Experience Influenced a Singapore Radiology Department's Response to the Coronavirus Disease (COVID-19) Epidemic. [Abstract]: OBJECTIVE. This article shares the ground operational perspective of how a tertiary hospital radiology department in Sing...
33,023,853
Transfus Apher Sci
Maintaining plasma quality and safety in the state of ongoing epidemic - The role of pathogen reduction.
In the field of transfusion medicine, many pathogen reduction techniques (PRTs) are currently available, including those based on photochemical (PI) and photodynamic inactivation (PDI). This is particularly important in the face of emerging viral pathogens that may pose a threat to blood recipients, as in the case of t...
covid-19;pathogen reduction;plasma for transfusion;sars-cov-2
Journal Article;Review
Wasiluk, Tomasz;Rogowska, Anna;Boczkowska-Radziwon, Barbara;Zebrowska, Agnieszka;Bolkun, Lukasz;Piszcz, Jaroslaw;Radziwon, Piotr
10.1016/j.transci.2020.102953
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Maintaining plasma quality and safety in the state of ongoing epidemic - The role of pathogen reduction. [Abstract]: In the field of transfusion medicine, many pathogen reduction techniques (PRTs) are currently available, including those based on photochemical (PI) and photodynamic inactivation (PDI). This is ...
32,975,066
Yonsei Med J
A Case of COVID-19 in a 45-Day-Old Infant with Persistent Fecal Virus Shedding for More Than 12 Weeks.
In this report, we describe the case of a SARS-CoV-2 infection (COVID-19) in an infant with mild fever and diarrhea in the absence of respiratory distress. A 45-day-old male infant with COVID-19 was transferred to our pediatric department. He had mild fever and diarrhea at admission. Positive-to-negative nasal swab con...
covid-19;diarrhea;infant;stool
Case Reports
Cho, Seung Man;Ha, Gyoung Yim
10.3349/ymj.2020.61.10.901
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: A Case of COVID-19 in a 45-Day-Old Infant with Persistent Fecal Virus Shedding for More Than 12 Weeks. [Abstract]: In this report, we describe the case of a SARS-CoV-2 infection (COVID-19) in an infant with mild fever and diarrhea in the absence of respiratory distress. A 45-day-old male infant with COVID-19 w...