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32,997,560
SLAS Technol
Detection Methods of COVID-19.
Since being first detected in China, coronavirus disease 2019 (COVID-19) has spread rapidly across the world, triggering a global pandemic with no viable cure in sight. As a result, national responses have focused on the effective minimization of the spread. Border control measures and travel restrictions have been imp...
cnn;covid-19;convolutional neural network;deep learning;diagnosis
Journal Article
Echtioui, Amira;Zouch, Wassim;Ghorbel, Mohamed;Mhiri, Chokri;Hamam, Habib
10.1177/2472630320962002
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Detection Methods of COVID-19. [Abstract]: Since being first detected in China, coronavirus disease 2019 (COVID-19) has spread rapidly across the world, triggering a global pandemic with no viable cure in sight. As a result, national responses have focused on the effective minimization of the spread. Border co...
32,901,377
World J Pediatr
Acral lesions in a pediatric population during the COVID-19 pandemic: a case series of 36 patients from a single hospital in Spain.
BACKGROUND: To describe the cutaneous acral findings in a pediatric population noticed during this pandemic. METHODS: A retrospective descriptive study was performed collecting data on 36 patients under 14 years old, presenting suspicious acral skin manifestations for coronavirus disease 2019 (COVID-19). RESULTS: Patie...
acral lesions;acute acro-ischemia;covid-19;chilblain-like
Journal Article
Roses-Gibert, Pau;Gimeno Castillo, Javier;Saenz Aguirre, Amaia;De la Torre Gomar, Francisco Javier;Carnero Gonzalez, Lucia;Martinez de Lagran Alvarez de Arcaya, Zurine;Gonzalez-Perez, Ricardo
10.1007/s12519-020-00390-0
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Acral lesions in a pediatric population during the COVID-19 pandemic: a case series of 36 patients from a single hospital in Spain. [Abstract]: BACKGROUND: To describe the cutaneous acral findings in a pediatric population noticed during this pandemic. METHODS: A retrospective descriptive study was performed c...
32,325,742
Molecules
Advances on Antiviral Activity of Morus spp. Plant Extracts: Human Coronavirus and Virus-Related Respiratory Tract Infections in the Spotlight.
(1) Background: Viral respiratory infections cause life-threatening diseases in millions of people worldwide every year. Human coronavirus and several picornaviruses are responsible for worldwide epidemic outbreaks, thus representing a heavy burden to their hosts. In the absence of specific treatments for human viral i...
morus spp.;antiviral activities;crude extract;human coronavirus;picornaviruses;respiratory viruses
Journal Article
Thabti, Ines;Albert, Quentin;Philippot, Stephanie;Dupire, Francois;Westerhuis, Brenda;Fontanay, Stephane;Risler, Arnaud;Kassab, Thomas;Elfalleh, Walid;Aferchichi, Ali;Varbanov, Mihayl
10.3390/molecules25081876
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Advances on Antiviral Activity of Morus spp. Plant Extracts: Human Coronavirus and Virus-Related Respiratory Tract Infections in the Spotlight. [Abstract]: (1) Background: Viral respiratory infections cause life-threatening diseases in millions of people worldwide every year. Human coronavirus and several pico...
32,771,432
Contemp Clin Trials
The effect of preventing subclinical transmission on the containment of COVID-19: Mathematical modeling and experience in Taiwan.
The control strategies preventing subclinical transmission differed among countries. A stochastic transmission model was used to assess the potential effectiveness of control strategies at controlling the COVID-19 outbreak. Three strategies included lack of prevention of subclinical transmission (Strategy A), partial p...
covid-19;outbreak control;quarantine;subclinical infection
Journal Article;Research Support, Non-U.S. Gov't
Tsou, Hsiao-Hui;Cheng, Yu-Chieh;Yuan, Hsiang-Yu;Hsu, Ya-Ting;Wu, Hsiao-Yu;Lee, Fang-Jing;Hsiung, Chao A;Chen, Wei J;Sytwu, Huey-Kang;Wu, Shiow-Ing;Shih, Shu-Man;Wen, Tzai-Hung;Kuo, Shu-Chen
10.1016/j.cct.2020.106101
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: The effect of preventing subclinical transmission on the containment of COVID-19: Mathematical modeling and experience in Taiwan. [Abstract]: The control strategies preventing subclinical transmission differed among countries. A stochastic transmission model was used to assess the potential effectiveness of co...
33,050,053
Vaccines (Basel)
Evolutionary Analysis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Reveals Genomic Divergence with Implications for Universal Vaccine Efficacy.
Coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is one of the pressing contemporary public health challenges. Investigations into the genomic structure of SARS-CoV-2 may inform ongoing vaccine development efforts and/or provide insights into vaccine efficacy to fi...
covid-19;sars-cov-2;genomic divergence;phylogenetic analysis;vaccine development
Journal Article
Yellapu, Nanda Kumar;Patel, Shachi;Zhang, Bo;Meier, Richard;Neums, Lisa;Pei, Dong;Xia, Qing;Rotich, Duncan;Zimmermann, Rosalyn C;Nissen, Emily;Bell-Glenn, Shelby;Shae, Whitney;Hu, Jinxiang;Chalise, Prabhakar;Chollet-Hinton, Lynn;Koestler, Devin C;Thompson, Jeffery A
10.3390/vaccines8040591
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Evolutionary Analysis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Reveals Genomic Divergence with Implications for Universal Vaccine Efficacy. [Abstract]: Coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is one of the pressing contempor...
32,723,623
Enferm Clin
Approaching grief and death in family members of patients with COVID-19: Narrative review.
OBJECTIVE: The objective of this review was to synthesize the possible evidence to establish recommendations on the approach of mourning and death in relatives of COVID-19 patients, as well as offering substitute resources for the necessary rituals and procedures in order to build up functional griefs and prevent compl...
actitudes ante la muerte;aislamiento de pacientes;attitudes death;farewell ritual;funeral rites;patient escort service;patient isolation;ritos funebres;ritual de despedida;servicio de acompanamiento de pacientes
Journal Article;Systematic Review
Araujo Hernandez, Miriam;Garcia Navarro, Sonia;Garcia-Navarro, E Begona
10.1016/j.enfcli.2020.05.011
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Approaching grief and death in family members of patients with COVID-19: Narrative review. [Abstract]: OBJECTIVE: The objective of this review was to synthesize the possible evidence to establish recommendations on the approach of mourning and death in relatives of COVID-19 patients, as well as offering substi...
33,002,560
J Infect
The role of Frailty on Adverse Outcomes Among Older Patients with COVID-19.
BACKGROUND: Diagnosis and screening of frailty, a condition characterized by an increased vulnerability to adverse outcomes of COVID-19, has emerged as an essential clinical tool which is strongly recommended by healthcare providers concerned with hospitalized elderly population. The data showing the role of frailty in...
covid-19;frailty
Journal Article;Research Support, Non-U.S. Gov't
Kundi, Harun;Cetin, Elif Hande Ozcan;Canpolat, Ugur;Aras, Sevgi;Celik, Osman;Ata, Naim;Birinci, Suayip;Cay, Serkan;Ozeke, Ozcan;Tanboga, Ibrahim Halil;Topaloglu, Serkan
10.1016/j.jinf.2020.09.029
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: The role of Frailty on Adverse Outcomes Among Older Patients with COVID-19. [Abstract]: BACKGROUND: Diagnosis and screening of frailty, a condition characterized by an increased vulnerability to adverse outcomes of COVID-19, has emerged as an essential clinical tool which is strongly recommended by healthcare ...
32,980,018
Environ Res
Disparate on-site access to water, sanitation, and food storage heighten the risk of COVID-19 spread in Sub-Saharan Africa.
COVID-19 is an active pandemic that likely poses an existential threat to humanity. Frequent handwashing, social distancing, and partial or total lockdowns are among the suite of measures prescribed by the World Health Organization (WHO) and being implemented across the world to contain the pandemic. However, existing ...
covid-19 response;food access;infectious disease;pandemic;preventive measures;public health;water and sanitation
Journal Article
Ekumah, Bernard;Armah, Frederick Ato;Yawson, David Oscar;Quansah, Reginald;Nyieku, Florence Esi;Owusu, Samuel Asiedu;Odoi, Justice Odoiquaye;Afitiri, Abdul-Rahaman
10.1016/j.envres.2020.109936
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Disparate on-site access to water, sanitation, and food storage heighten the risk of COVID-19 spread in Sub-Saharan Africa. [Abstract]: COVID-19 is an active pandemic that likely poses an existential threat to humanity. Frequent handwashing, social distancing, and partial or total lockdowns are among the suite...
32,577,325
Cureus
Coronavirus Disease 2019 (COVID-19) in Children: Vulnerable or Spared? A Systematic Review.
The ongoing pandemic of coronavirus disease 2019 (COVID-19) has affected people from all cultures, religions, gender, and age groups around the world. In the last few months, several studies have been conducted on various aspects of COVID-19. Our goal was to see if the pediatric population is vulnerable to this infecti...
corona virus;covid-19;covid-19 in children;covid-19 in neonates;covid-19 outbreak;novel corona virus;sars-cov-2 (severe acute respiratory syndrome coronavirus -2);sars-cov-2 in pediatric patients
Journal Article;Review
Saleem, Hajra;Rahman, Jawaria;Aslam, Nida;Murtazaliev, Salikh;Khan, Safeera
10.7759/cureus.8207
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Coronavirus Disease 2019 (COVID-19) in Children: Vulnerable or Spared? A Systematic Review. [Abstract]: The ongoing pandemic of coronavirus disease 2019 (COVID-19) has affected people from all cultures, religions, gender, and age groups around the world. In the last few months, several studies have been conduc...
32,893,248
Rinsho Shinkeigaku
[MRI and intravenous thrombolysis for unclear-onset stroke during the COVID-19 pandemic: a case report].
During the COVID-19 pandemic in 2020, an 81-year-old afebrile woman was transported to our institute at 44 minutes after she was found to have global aphasia and weakness of the right extremities. The onset time was unclear. CT showed an occlusion of the left middle cerebral artery without early ischemic changes. MRI r...
covid-19;mri;intravenous thrombolysis;stroke;unclear onset
Case Reports;Journal Article
Kamogawa, Naruhiko;Egashira, Shuhei;Tanaka, Kanta;Shiozawa, Masayuki;Inoue, Manabu;Ohta, Yasutoshi;Nishii, Tatsuya;Fukuda, Tetsuya;Koga, Masatoshi
10.5692/clinicalneurol.cn-001481
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: [MRI and intravenous thrombolysis for unclear-onset stroke during the COVID-19 pandemic: a case report]. [Abstract]: During the COVID-19 pandemic in 2020, an 81-year-old afebrile woman was transported to our institute at 44 minutes after she was found to have global aphasia and weakness of the right extremitie...
32,529,575
J Neurol
Clinical manifestations and evidence of neurological involvement in 2019 novel coronavirus SARS-CoV-2: a systematic review and meta-analysis.
BACKGROUND: Coronavirus disease 2019 (COVID-19) has become a global pandemic, affecting millions of people. However, clinical research on its neurological manifestations is thus far limited. In this study, we aimed to systematically collect and investigate the clinical manifestations and evidence of neurological involv...
covid-19;inflammation;neurological manifestations;sars-cov-2;systematic review
Journal Article;Meta-Analysis;Systematic Review
Wang, Lei;Shen, Yin;Li, Man;Chuang, Haoyu;Ye, Youfan;Zhao, Hongyang;Wang, Haijun
10.1007/s00415-020-09974-2
[ 0, 1, 0, 1, 0, 0, 0 ]
[Title]: Clinical manifestations and evidence of neurological involvement in 2019 novel coronavirus SARS-CoV-2: a systematic review and meta-analysis. [Abstract]: BACKGROUND: Coronavirus disease 2019 (COVID-19) has become a global pandemic, affecting millions of people. However, clinical research on its neurological ma...
32,942,792
Pain Physician
Steroid Distancing in Interventional Pain Management During COVID-19 and Beyond: Safe, Effective and Practical Approach.
BACKGROUND: Since the late 1940s, corticosteroids have been a mainstay class of agents in multiple interventional techniques and intra-articular injections. Exogenous glucocorticoids are structurally and pharmacologically similar to the endogenous hormones. As such, multiple actions of corticosteroids are exhibited, in...
steroid distancing;chronic pain;epidural injections;local anesthetic alone;local anesthetic with steroid;physical distancing
Journal Article;Review
Manchikanti, Laxmaiah;Kosanovic, Radomir;Vanaparthy, Rachana;Vangala, Brahma Prasad;Soin, Amol;Sachdeva, Harsh;Shah, Shalini;Knezevic, Nebojsa Nick;Hirsch, Joshua A
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Steroid Distancing in Interventional Pain Management During COVID-19 and Beyond: Safe, Effective and Practical Approach. [Abstract]: BACKGROUND: Since the late 1940s, corticosteroids have been a mainstay class of agents in multiple interventional techniques and intra-articular injections. Exogenous glucocortic...
32,834,620
Chaos Solitons Fractals
Assessment of lockdown effect in some states and overall India: A predictive mathematical study on COVID-19 outbreak.
In the absence of neither an effective treatment or vaccine and with an incomplete understanding of the epidemiological cycle, Govt. has implemented a nationwide lockdown to reduce COVID-19 transmission in India. To study the effect of social distancing measure, we considered a new mathematical model on COVID-19 that i...
covid-19;lockdown effect;mathematical model;outbreak containment policy
Journal Article
Sardar, Tridip;Nadim, Sk Shahid;Rana, Sourav;Chattopadhyay, Joydev
10.1016/j.chaos.2020.110078
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Assessment of lockdown effect in some states and overall India: A predictive mathematical study on COVID-19 outbreak. [Abstract]: In the absence of neither an effective treatment or vaccine and with an incomplete understanding of the epidemiological cycle, Govt. has implemented a nationwide lockdown to reduce ...
32,566,896
Antib Ther
Perspectives on the development of neutralizing antibodies against SARS-CoV-2.
SARS-CoV-2 gains entry to human cells through its spike (S) protein binding to angiotensin-converting enzyme 2 (ACE2). Therefore, the receptor binding domain (RBD) of the S protein is the primary target for neutralizing antibodies. Selection of broad-neutralizing antibodies against SARS-CoV-2 and SARS-CoV is attractive...
covid-19;sars-cov;sars-cov-2;neutralizing antibody;spike (s) protein
Journal Article;Review
Ho, Mitchell
10.1093/abt/tbaa009
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Perspectives on the development of neutralizing antibodies against SARS-CoV-2. [Abstract]: SARS-CoV-2 gains entry to human cells through its spike (S) protein binding to angiotensin-converting enzyme 2 (ACE2). Therefore, the receptor binding domain (RBD) of the S protein is the primary target for neutralizing ...
33,066,701
Viruses
Amplicon-Based Detection and Sequencing of SARS-CoV-2 in Nasopharyngeal Swabs from Patients With COVID-19 and Identification of Deletions in the Viral Genome That Encode Proteins Involved in Interferon Antagonism.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19). Sequencing the viral genome as the outbreak progresses is important, particularly in the identification of emerging isolates with different pathogenic potential and to identify whether nucleotide ...
minion;sars-cov-2;amplicon;next-generation sequencing
Journal Article;Research Support, Non-U.S. Gov't;Research Support, U.S. Gov't, Non-P.H.S.
Moore, Shona C;Penrice-Randal, Rebekah;Alruwaili, Muhannad;Randle, Nadine;Armstrong, Stuart;Hartley, Catherine;Haldenby, Sam;Dong, Xiaofeng;Alrezaihi, Abdulrahman;Almsaud, Mai;Bentley, Eleanor;Clark, Jordan;Garcia-Dorival, Isabel;Gilmore, Paul;Han, Ximeng;Jones, Benjamin;Luu, Lisa;Sharma, Parul;Shawli, Ghada;Sun, Yani;...
10.3390/v12101164
[ 0, 1, 0, 1, 0, 0, 0 ]
[Title]: Amplicon-Based Detection and Sequencing of SARS-CoV-2 in Nasopharyngeal Swabs from Patients With COVID-19 and Identification of Deletions in the Viral Genome That Encode Proteins Involved in Interferon Antagonism. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent o...
32,785,885
Infection
Diagnosis of COVID-19 using multiple antibody assays in two cases with negative PCR results from nasopharyngeal swabs.
We report of two cases of progressed COVID-19 with negative PCR tests from nasopharyngeal swabs, in whom diagnosis was made by different antibody assays, including a lateral flow rapid test and multiple commercial ELISAs, finally confirmed by comprehensive serological assays. These cases highlight that commercial ELISA...
antibodies;coronavirus;immunoassay;pcr negative;rapid test;sars
Case Reports;Journal Article
Traugott, Marianna Theresia;Hoepler, Wolfgang;Seitz, Tamara;Baumgartner, Sebastian;Karolyi, Mario;Pawelka, Erich;Friese, Emanuela;Neuhold, Stephanie;Kelani, Hasan;Thalhammer, Florian;Zoufaly, Alexander;Laferl, Hermann;Aberle, Judith Helene;Wenisch, Christoph;Puchhammer-Stockl, Elisabeth;Stiasny, Karin;Aberle, Stephan W...
10.1007/s15010-020-01497-2
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Diagnosis of COVID-19 using multiple antibody assays in two cases with negative PCR results from nasopharyngeal swabs. [Abstract]: We report of two cases of progressed COVID-19 with negative PCR tests from nasopharyngeal swabs, in whom diagnosis was made by different antibody assays, including a lateral flow r...
32,810,081
Am J Case Rep
Airway Hygiene in COVID-19 Pneumonia: Treatment Responses of 3 Critically Ill Cruise Ship Employees.
BACKGROUND COVID-19, the disease entity caused by the novel severe acute respiratory coronavirus 2 (SARS-CoV-2), continues to pose a major therapeutic challenge for clinicians. At present, an effective treatment regimen and vaccination has not been established. Many patients develop severe symptoms requiring endotrache...
Case Reports;Journal Article
Farooqi, Faryal I;Morgan, Richard C;Dhawan, Naveen;Dinh, John;Yatzkan, George;Michel, George
10.12659/AJCR.926596
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Airway Hygiene in COVID-19 Pneumonia: Treatment Responses of 3 Critically Ill Cruise Ship Employees. [Abstract]: BACKGROUND COVID-19, the disease entity caused by the novel severe acute respiratory coronavirus 2 (SARS-CoV-2), continues to pose a major therapeutic challenge for clinicians. At present, an effect...
32,640,936
Lupus
Severe refractory thrombocytopenia in a woman positive for coronavirus disease 2019 with lupus and antiphospholipid syndrome.
The coronavirus disease 2019 (COVID-19) pandemic has created new challenges that necessitate prompt responses in unexpected clinical situations. Multiple extrapulmonary manifestations and complications of COVID-19 have already been described, but only scattered data are present on immunologic manifestations. We present...
covid-19;antiphospholipid syndrome;immune thrombocytopenia;systemic lupus erythematosus
Case Reports;Journal Article
Hayden, Alina;Vyas-Lahar, Aishwarya;Rella, Vincent;Rudinskaya, Alla
10.1177/0961203320940389
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Severe refractory thrombocytopenia in a woman positive for coronavirus disease 2019 with lupus and antiphospholipid syndrome. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic has created new challenges that necessitate prompt responses in unexpected clinical situations. Multiple extrapulmonary mani...
32,532,029
Int J Environ Res Public Health
The Emergence of Risk Communication Networks and the Development of Citizen Health-Related Behaviors during the COVID-19 Pandemic: Social Selection and Contagion Processes.
Amid the novel coronavirus pandemic, a variety of public health strategies have been implemented by governments worldwide. However, the fact that strict government mandates focus on physical distancing does not mean that social connectedness for voluntary risk communication among citizens should be sacrificed. Furtherm...
covid-19;citizen behaviors;coevolution;health resilience;risk communication networks;stochastic actor-oriented model;voluntary public health measures
Journal Article
Lim, Seunghoo;Nakazato, Hiromi
10.3390/ijerph17114148
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Emergence of Risk Communication Networks and the Development of Citizen Health-Related Behaviors during the COVID-19 Pandemic: Social Selection and Contagion Processes. [Abstract]: Amid the novel coronavirus pandemic, a variety of public health strategies have been implemented by governments worldwide. How...
32,386,942
Dig Liver Dis
Endoscopy during the Covid-19 outbreak: experience and recommendations from a single center in a high-incidence scenario.
A dramatic SARS-Cov-2 outbreak is hitting Italy hard. To face the new scenario all the hospitals have been re-organised in order to reduce all the outpatient services and to devote almost all their personnel and resources to the management of Covid-19 patients. As a matter of fact, all the services have undergone a dee...
coronavirus;covid-19;endoscopy;sars-cov-2
Journal Article
Elli, Luca;Rimondi, Alessandro;Scaramella, Lucia;Topa, Matilde;Vecchi, Maurizio;Mangioni, Davide;Gori, Andrea;Penagini, Roberto
10.1016/j.dld.2020.04.018
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Endoscopy during the Covid-19 outbreak: experience and recommendations from a single center in a high-incidence scenario. [Abstract]: A dramatic SARS-Cov-2 outbreak is hitting Italy hard. To face the new scenario all the hospitals have been re-organised in order to reduce all the outpatient services and to dev...
33,029,193
Comput Math Methods Med
Assessment of the Potential Adverse Events Related to Ribavirin-Interferon Combination for Novel Coronavirus Therapy.
Purpose: We aimed to analyze and evaluate the safety signals of ribavirin-interferon combination through data mining of the US Food and Drug Administration Adverse Event Reporting System (FAERS), so as to provide reference for the rationale use of these agents in the management of relevant toxicities emerging in patien...
Journal Article
Shan, Wenya;Hong, Dongsheng;Zhu, Jieqiang;Zhao, Qingwei
10.1155/2020/1391583
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Assessment of the Potential Adverse Events Related to Ribavirin-Interferon Combination for Novel Coronavirus Therapy. [Abstract]: Purpose: We aimed to analyze and evaluate the safety signals of ribavirin-interferon combination through data mining of the US Food and Drug Administration Adverse Event Reporting S...
33,031,047
J Med Internet Res
Telemedicine Usage Among Urologists During the COVID-19 Pandemic: Cross-Sectional Study.
BACKGROUND: Prior to the COVID-19 pandemic, urology was one of the specialties with the lowest rates of telemedicine and videoconferencing use. Common barriers to the implementation of telemedicine included a lack of technological literacy, concerns with reimbursement, and resistance to changes in the workplace. In res...
covid-19;barrier;coronavirus;cross-sectional;implementation;perception;technology;telehealth;telemedicine;urology;usability
Journal Article
Dubin, Justin M;Wyant, W Austin;Balaji, Navin C;Ong, William Lk;Kettache, Reda H;Haffaf, Malik;Zouari, Skander;Santillan, Diego;Autran Gomez, Ana Maria;Sadeghi-Nejad, Hossein;Loeb, Stacy;Borin, James F;Gomez Rivas, Juan;Grummet, Jeremy;Ramasamy, Ranjith;Teoh, Jeremy Y C
10.2196/21875
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Telemedicine Usage Among Urologists During the COVID-19 Pandemic: Cross-Sectional Study. [Abstract]: BACKGROUND: Prior to the COVID-19 pandemic, urology was one of the specialties with the lowest rates of telemedicine and videoconferencing use. Common barriers to the implementation of telemedicine included a l...
32,944,437
Cureus
Incidental PET/CT Findings of Suspected COVID-19 in a Region of High Prevalence.
We describe a case of suspected COVID-19 pneumonia in a 61-year-old male with known primary central nervous system diffuse large B-cell lymphoma (DLBCL) who underwent restaging PET/CT during the initial peak of infection of COVID-19 pneumonia within the New York region. At the time of his routine PET-CT to assess for d...
covid-19;fdg;pet/ct;sars-cov-2 infection
Case Reports
Franceschi, Ana M;Clifton, Michael;Ahmed, Osama;Matthews, Robert;Franceschi, Dinko
10.7759/cureus.9716
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Incidental PET/CT Findings of Suspected COVID-19 in a Region of High Prevalence. [Abstract]: We describe a case of suspected COVID-19 pneumonia in a 61-year-old male with known primary central nervous system diffuse large B-cell lymphoma (DLBCL) who underwent restaging PET/CT during the initial peak of infecti...
32,862,474
Echocardiography
Critical care ultrasonography during COVID-19 pandemic: The ORACLE protocol.
BACKGROUND: Coronavirus disease 2019 (COVID-19) is characterized by severe lung involvement and hemodynamic alterations. Critical care ultrasonography is vital because it provides real time information for diagnosis and treatment. Suggested protocols for image acquisition and measurements have not yet been evaluated. M...
echocardiography;right ventricular function;ultrasonography
Journal Article;Multicenter Study
Garcia-Cruz, Edgar;Manzur-Sandoval, Daniel;Rascon-Sabido, Rafael;Gopar-Nieto, Rodrigo;Barajas-Campos, Ricardo Leopoldo;Jordan-Rios, Antonio;Sierra-Lara Martinez, Daniel;Jimenez-Rodriguez, Gian Manuel;Murillo-Ochoa, Adriana Lizeth;Diaz-Mendez, Arturo;Lazcano-Diaz, Emmanuel;Araiza-Garaygordobil, Diego;Cabello-Lopez, Alej...
10.1111/echo.14837
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Critical care ultrasonography during COVID-19 pandemic: The ORACLE protocol. [Abstract]: BACKGROUND: Coronavirus disease 2019 (COVID-19) is characterized by severe lung involvement and hemodynamic alterations. Critical care ultrasonography is vital because it provides real time information for diagnosis and tr...
32,541,865
Cell Res
Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease.
A new coronavirus SARS-CoV-2, also called novel coronavirus 2019 (2019-nCoV), started to circulate among humans around December 2019, and it is now widespread as a global pandemic. The disease caused by SARS-CoV-2 virus is called COVID-19, which is highly contagious and has an overall mortality rate of 6.35% as of May ...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Ma, Chunlong;Sacco, Michael Dominic;Hurst, Brett;Townsend, Julia Alma;Hu, Yanmei;Szeto, Tommy;Zhang, Xiujun;Tarbet, Bart;Marty, Michael Thomas;Chen, Yu;Wang, Jun
10.1038/s41422-020-0356-z
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease. [Abstract]: A new coronavirus SARS-CoV-2, also called novel coronavirus 2019 (2019-nCoV), started to circulate among humans around December 2019, and it is now widespread as a global pa...
32,777,008
JAMA Ophthalmol
Practice Patterns and Responsiveness to Simulated Common Ocular Complaints Among US Ophthalmology Centers During the COVID-19 Pandemic.
Importance: The coronavirus disease 2019 (COVID-19) pandemic has drastically changed how comprehensive ophthalmology practices care for patients. Objective: To report practice patterns for common ocular complaints during the initial stage of the COVID-19 pandemic among comprehensive ophthalmology practices in the US. D...
Journal Article
Starr, Matthew R;Israilevich, Rachel;Zhitnitsky, Michael;Cheng, Qianqian E;Soares, Rebecca R;Patel, Luv G;Ammar, Michael J;Khan, M Ali;Yonekawa, Yoshihiro;Ho, Allen C;Cohen, Michael N;Sridhar, Jayanth;Kuriyan, Ajay E
10.1001/jamaophthalmol.2020.3237
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Practice Patterns and Responsiveness to Simulated Common Ocular Complaints Among US Ophthalmology Centers During the COVID-19 Pandemic. [Abstract]: Importance: The coronavirus disease 2019 (COVID-19) pandemic has drastically changed how comprehensive ophthalmology practices care for patients. Objective: To rep...
32,773,986
Bioinformation
Towards Neuro-CoViD-19.
CoViD-19 is the current pandemic caused by the Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2). Infection by SARS-CoV-2 occurs via the binding of its S protein to the angiotensin-converting enzyme-2 receptor (ACE2-R). S binding to ACE2-R leads to a drop in ACE2, a homolog of angiotensin converting enzyme ...
angiotensin-converting enzyme-2 receptor (ace2-r);central nervous system (cns);corona virus disease 2019 (covid-19);severe acute respiratory syndrome corona virus-2 (sars-cov-2);transmembrane protease serine-2 (tmprss2)
Editorial
Chiappelli, Francesco
10.6026/97320630016288
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Towards Neuro-CoViD-19. [Abstract]: CoViD-19 is the current pandemic caused by the Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2). Infection by SARS-CoV-2 occurs via the binding of its S protein to the angiotensin-converting enzyme-2 receptor (ACE2-R). S binding to ACE2-R leads to a drop in ACE2...
32,807,244
Epidemiol Infect
Increasing molecular diagnostic capacity and COVID-19 incidence in Brazil.
Different countries have adopted strategies for the early detection of SARS-CoV-2 since the declaration of community transmission by the World Health Organization (WHO) and timely diagnosis has been considered one of the major obstacles for surveillance and healthcare. Here, we report the increase of the number of labo...
covid-19;diagnosis;epidemiology;infectious disease;laboratory tests
Journal Article
Grotto, Rejane Maria Tommasini;Santos Lima, Rodrigo;de Almeida, Gabriel Berg;Ferreira, Claudia Pio;Guimaraes, Raul Borges;Pronunciate, Micheli;Azevedo, Edmur;Catao, Rafael de Castro;Fortaleza, Carlos Magno Castelo Branco
10.1017/S0950268820001818
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Increasing molecular diagnostic capacity and COVID-19 incidence in Brazil. [Abstract]: Different countries have adopted strategies for the early detection of SARS-CoV-2 since the declaration of community transmission by the World Health Organization (WHO) and timely diagnosis has been considered one of the maj...
32,930,058
J Biomol Struct Dyn
Naltrexone a potential therapeutic candidate for COVID-19.
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the cause of Coronavirus Disease (COVID-19) that has resulted in a global pandemic. At the time of writing, approximately 16.06 million cases have been reported worldwide. Like other coronaviruses, SARS-CoV-2 relies on the surface Spike glycoprotein to acc...
covid-19;sars-cov-2;drug repurposing;molecular docking;naltrexone;structural bioinformatics
Journal Article
Choubey, Abhinav;Dehury, Budheswar;Kumar, Sunil;Medhi, Bikash;Mondal, Prosenjit
10.1080/07391102.2020.1820379
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Naltrexone a potential therapeutic candidate for COVID-19. [Abstract]: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the cause of Coronavirus Disease (COVID-19) that has resulted in a global pandemic. At the time of writing, approximately 16.06 million cases have been reported worldwide. Like...
32,783,787
Infect Control Hosp Epidemiol
Inactivation of Severe Acute Respiratory Coronavirus Virus 2 (SARS-CoV-2) and Diverse RNA and DNA Viruses on Three-Dimensionally Printed Surgical Mask Materials.
BACKGROUND: Personal protective equipment (PPE) is a critical need during the coronavirus disease 2019 (COVID-19) pandemic. Alternative sources of surgical masks, including 3-dimensionally (3D) printed approaches that may be reused, are urgently needed to prevent PPE shortages. Few data exist identifying decontaminatio...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Welch, Jennifer L;Xiang, Jinhua;Mackin, Samantha R;Perlman, Stanley;Thorne, Peter;O'Shaughnessy, Patrick;Strzelecki, Brian;Aubin, Patrick;Ortiz-Hernandez, Monica;Stapleton, Jack T
10.1017/ice.2020.417
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Inactivation of Severe Acute Respiratory Coronavirus Virus 2 (SARS-CoV-2) and Diverse RNA and DNA Viruses on Three-Dimensionally Printed Surgical Mask Materials. [Abstract]: BACKGROUND: Personal protective equipment (PPE) is a critical need during the coronavirus disease 2019 (COVID-19) pandemic. Alternative s...
32,526,068
Arthritis Care Res (Hoboken)
Perspectives of Patients With Rheumatic Diseases in the Early Phase of COVID-19.
OBJECTIVE: To determine health perceptions of patients with rheumatic diseases in the early phase of the coronavirus disease 2019 (COVID-19) pandemic. METHODS: Rheumatology patients at a single center received via text message the Australian Rheumatology Association COVID-19 information sheet and an invitation to parti...
Journal Article
Antony, Anna;Connelly, Kathryn;De Silva, Thilinie;Eades, Laura;Tillett, William;Ayoub, Sally;Morand, Eric
10.1002/acr.24347
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Perspectives of Patients With Rheumatic Diseases in the Early Phase of COVID-19. [Abstract]: OBJECTIVE: To determine health perceptions of patients with rheumatic diseases in the early phase of the coronavirus disease 2019 (COVID-19) pandemic. METHODS: Rheumatology patients at a single center received via text...
32,699,972
Virol Sin
Mild Cytokine Elevation, Moderate CD4(+) T Cell Response and Abundant Antibody Production in Children with COVID-19.
Children with Coronavirus Disease 2019 (COVID-19) were reported to show milder symptoms and better prognosis than their adult counterparts, but the difference of immune response against SARS-CoV-2 between children and adults hasn't been reported. Therefore we initiated this study to figure out the features of immune re...
antibody dynamics;covid-19;cytokine;sars-cov-2;t cell immune response
Journal Article
Jia, Ran;Wang, Xiangshi;Liu, Pengcheng;Liang, Xiaozhen;Ge, Yanling;Tian, He;Chang, Hailing;Zhou, Hao;Zeng, Mei;Xu, Jin
10.1007/s12250-020-00265-8
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Mild Cytokine Elevation, Moderate CD4(+) T Cell Response and Abundant Antibody Production in Children with COVID-19. [Abstract]: Children with Coronavirus Disease 2019 (COVID-19) were reported to show milder symptoms and better prognosis than their adult counterparts, but the difference of immune response agai...
32,842,269
Zhonghua Xin Xue Guan Bing Za Zhi
[Predictive value of neutrophil/lymphocyte ratio on myocardial injury in severe COVID-19 patients].
Objective: To explore the predictive value of neutrophil/lymphocyte ratio (NLR) on myocardial injury in severe COVID-19 patients. Methods: In this single-center retrospective cohort study, we collected and analyzed data form 133 severe COVID-19 patients admitted to Renmin Hospital of Wuhan University (Eastern District)...
covid-19;heart injury;neutrophil/lymphocyte ratio
Journal Article
Chen, Y;Wang, K J;Luo, Y C;Wang, B Z;Zhang, M M;Xu, Y Q;Yang, Y N;Ma, Y T
10.3760/cma.j.cn112148-20200422-00336
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: [Predictive value of neutrophil/lymphocyte ratio on myocardial injury in severe COVID-19 patients]. [Abstract]: Objective: To explore the predictive value of neutrophil/lymphocyte ratio (NLR) on myocardial injury in severe COVID-19 patients. Methods: In this single-center retrospective cohort study, we collect...
32,983,830
Infect Dis Ther
Factors Associated with Good Patient Outcomes Following Convalescent Plasma in COVID-19: A Prospective Phase II Clinical Trial.
Introduction: Coronavirus disease 2019 (COVID-19) is a viral respiratory syndrome caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This novel virus was discovered in Wuhan City, Hubei Province, China, in December 2019. As of September 6, 2020, confirmed cases have risen to more than 27,000,000 wo...
adult respiratory distress syndrome;covid-19;covid-19 serotherapy;hospital mortality;length of stay;phase ii clinical trial;plasma;prospective studies;severe acute respiratory syndrome coronavirus 2;ventilation
Journal Article
Ibrahim, Danyal;Dulipsingh, Latha;Zapatka, Lisa;Eadie, Reginald;Crowell, Rebecca;Williams, Kendra;Wakefield, Dorothy B;Cook, Lisa;Puff, Jennifer;Hussain, Syed A
10.1007/s40121-020-00341-2
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Factors Associated with Good Patient Outcomes Following Convalescent Plasma in COVID-19: A Prospective Phase II Clinical Trial. [Abstract]: Introduction: Coronavirus disease 2019 (COVID-19) is a viral respiratory syndrome caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This novel virus ...
32,469,265
J Biomol Struct Dyn
Docking study of chloroquine and hydroxychloroquine interaction with RNA binding domain of nucleocapsid phospho-protein - an in silico insight into the comparative efficacy of repurposing antiviral drugs.
Recent outbreak of novel Coronavirus disease () pandemic around the world is associated with severe acute respiratory syndrome. The death toll associated with the pandemic is increasing day by day. SARS-CoV-2 is an enveloped virus and its N terminal domain (NTD) of Nucleocapsid protein (N protein) binds to the viral (+...
coronaviruses;rna binding domain of nucleocapsid phosphoprotein;sars-cov-2;chloroquine;docking studies;hydroxychloroquine
Journal Article
Amin, Muhammad;Abbas, Ghazanfar
10.1080/07391102.2020.1775703
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Docking study of chloroquine and hydroxychloroquine interaction with RNA binding domain of nucleocapsid phospho-protein - an in silico insight into the comparative efficacy of repurposing antiviral drugs. [Abstract]: Recent outbreak of novel Coronavirus disease () pandemic around the world is associated with s...
32,669,297
Science
Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications.
Coronavirus disease 2019 (COVID-19) is currently a global pandemic, but human immune responses to the virus remain poorly understood. We used high-dimensional cytometry to analyze 125 COVID-19 patients and compare them with recovered and healthy individuals. Integrated analysis of ~200 immune and ~50 clinical features ...
Journal Article;Observational Study;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Mathew, Divij;Giles, Josephine R;Baxter, Amy E;Oldridge, Derek A;Greenplate, Allison R;Wu, Jennifer E;Alanio, Cecile;Kuri-Cervantes, Leticia;Pampena, M Betina;D'Andrea, Kurt;Manne, Sasikanth;Chen, Zeyu;Huang, Yinghui Jane;Reilly, John P;Weisman, Ariel R;Ittner, Caroline A G;Kuthuru, Oliva;Dougherty, Jeanette;Nzingha, K...
10.1126/science.abc8511
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications. [Abstract]: Coronavirus disease 2019 (COVID-19) is currently a global pandemic, but human immune responses to the virus remain poorly understood. We used high-dimensional cytometry to analyze 125 COVID-19 pat...
32,717,841
Healthcare (Basel)
Quadrupling the N95 Supply during the COVID-19 Crisis with an Innovative 3D-Printed Mask Adaptor.
The need for personal protective equipment during the COVID-19 pandemic is far outstripping our ability to manufacture and distribute these supplies to hospitals. In particular, the medical N95 mask shortage is resulting in healthcare providers reusing masks or utilizing masks with filtration properties that do not mee...
3d printing;covid-19;n95 masks;personal protective equipment
Journal Article
Imbrie-Moore, Annabel M;Park, Matthew H;Zhu, Yuanjia;Paulsen, Michael J;Wang, Hanjay;Woo, Y Joseph
10.3390/healthcare8030225
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Quadrupling the N95 Supply during the COVID-19 Crisis with an Innovative 3D-Printed Mask Adaptor. [Abstract]: The need for personal protective equipment during the COVID-19 pandemic is far outstripping our ability to manufacture and distribute these supplies to hospitals. In particular, the medical N95 mask sh...
32,574,319
Front Med (Lausanne)
Evaluation of the Secondary Transmission Pattern and Epidemic Prediction of COVID-19 in the Four Metropolitan Areas of China.
Understanding the transmission dynamics of COVID-19 is crucial for evaluating its spread pattern, especially in metropolitan areas of China, as its spread could lead to secondary outbreaks. In addition, the experiences gained and lessons learned from China have the potential to provide evidence to support other metropo...
covid-19;seir;basic reproduction number;epidemic prediction;novel coronavirus;secondary transmission
Journal Article
Su, Longxiang;Hong, Na;Zhou, Xiang;He, Jie;Ma, Yingying;Jiang, Huizhen;Han, Lin;Chang, Fengxiang;Shan, Guangliang;Zhu, Weiguo;Long, Yun
10.3389/fmed.2020.00171
[ 0, 0, 1, 0, 1, 1, 0 ]
[Title]: Evaluation of the Secondary Transmission Pattern and Epidemic Prediction of COVID-19 in the Four Metropolitan Areas of China. [Abstract]: Understanding the transmission dynamics of COVID-19 is crucial for evaluating its spread pattern, especially in metropolitan areas of China, as its spread could lead to seco...
32,422,076
Ann Intern Med
Pulmonary Arterial Thrombosis in COVID-19 With Fatal Outcome : Results From a Prospective, Single-Center, Clinicopathologic Case Series.
BACKGROUND: Coronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly become pandemic, with substantial mortality. OBJECTIVE: To evaluate the pathologic changes of organ systems and the clinicopathologic basis for severe and fatal outcomes. DESIGN: ...
Journal Article
Lax, Sigurd F;Skok, Kristijan;Zechner, Peter;Kessler, Harald H;Kaufmann, Norbert;Koelblinger, Camillo;Vander, Klaus;Bargfrieder, Ute;Trauner, Michael
10.7326/M20-2566
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Pulmonary Arterial Thrombosis in COVID-19 With Fatal Outcome : Results From a Prospective, Single-Center, Clinicopathologic Case Series. [Abstract]: BACKGROUND: Coronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly become pandemic, with...
33,022,464
Sci Total Environ
The determinants of COVID-19 case fatality rate (CFR) in the Italian regions and provinces: An analysis of environmental, demographic, and healthcare factors.
The Italian government has been one of the most responsive to COVID-2019 emergency, through the adoption of quick and increasingly stringent measures to contain the outbreak. Despite this, Italy has suffered a huge human and social cost, especially in Lombardy. The aim of this paper is dual: i) first, to investigate th...
covid-19;case fatality rate;environmental pollution;health system saturation;italy;weather
Journal Article
Perone, Gaetano
10.1016/j.scitotenv.2020.142523
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The determinants of COVID-19 case fatality rate (CFR) in the Italian regions and provinces: An analysis of environmental, demographic, and healthcare factors. [Abstract]: The Italian government has been one of the most responsive to COVID-2019 emergency, through the adoption of quick and increasingly stringent...
32,694,043
Transfus Apher Sci
Clinical efficacy of convalescent plasma for treatment of COVID-19 infections: Results of a multicenter clinical study.
Since Dec. 2019 the new coronavirus (SARS-CoV-2) has infected millions and claimed life of several hundred thousand worldwide. However, so far no approved vaccine or drug therapy is available for treatment of virus infection. Convalescent plasma has been considered a potential modality for COVID-19 infection. One hundr...
covid-19;clinical trial;convalescent plasma;hospital stay;mortality rate
Clinical Trial;Journal Article;Multicenter Study
Abolghasemi, Hassan;Eshghi, Peyman;Cheraghali, Abdol Majid;Imani Fooladi, Abbas Ali;Bolouki Moghaddam, Farzaneh;Imanizadeh, Sina;Moeini Maleki, Matin;Ranjkesh, Mohammad;Rezapour, Mohammad;Bahramifar, Ali;Einollahi, Behzad;Hosseini, Mohammad Javad;Jafari, Nematollah Joneidi;Nikpouraghdam, Mohamad;Sadri, Nariman;Tazik, M...
10.1016/j.transci.2020.102875
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Clinical efficacy of convalescent plasma for treatment of COVID-19 infections: Results of a multicenter clinical study. [Abstract]: Since Dec. 2019 the new coronavirus (SARS-CoV-2) has infected millions and claimed life of several hundred thousand worldwide. However, so far no approved vaccine or drug therapy ...
32,692,801
Bioinformatics
COVID-19 Docking Server: a meta server for docking small molecules, peptides and antibodies against potential targets of COVID-19.
MOTIVATION: The coronavirus disease 2019 (COVID-19) caused by a new type of coronavirus has been emerging from China and led to thousands of death globally since December 2019. Despite many groups have engaged in studying the newly emerged virus and searching for the treatment of COVID-19, the understanding of the COVI...
Journal Article;Research Support, Non-U.S. Gov't
Kong, Ren;Yang, Guangbo;Xue, Rui;Liu, Ming;Wang, Feng;Hu, Jianping;Guo, Xiaoqiang;Chang, Shan
10.1093/bioinformatics/btaa645
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: COVID-19 Docking Server: a meta server for docking small molecules, peptides and antibodies against potential targets of COVID-19. [Abstract]: MOTIVATION: The coronavirus disease 2019 (COVID-19) caused by a new type of coronavirus has been emerging from China and led to thousands of death globally since Decemb...
32,745,217
Orthopedics
Outpatient Orthopedic Rehabilitation in New York State During the COVID-19 Pandemic: Therapist Perspectives.
The COVID-19 pandemic has had a strong impact on the care of orthopedic patients. This impact has been particularly difficult in New York State, which experienced the largest number of COVID-19 cases and led to a state- mandated pause on all elective surgeries. As a result, physical and occupational therapists became t...
Journal Article
Parnes, Nata;Tousant, Cheryl;Perrine, Jeff;DeFranco, Michael J
10.3928/01477447-20200721-16
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Outpatient Orthopedic Rehabilitation in New York State During the COVID-19 Pandemic: Therapist Perspectives. [Abstract]: The COVID-19 pandemic has had a strong impact on the care of orthopedic patients. This impact has been particularly difficult in New York State, which experienced the largest number of COVID...
32,622,168
Sci Total Environ
Rethinking and optimising plastic waste management under COVID-19 pandemic: Policy solutions based on redesign and reduction of single-use plastics and personal protective equipment.
Plastics have been on top of the political agenda in Europe and across the world to reduce plastic leakage and pollution. However, the COVID-19 pandemic has severely disrupted plastic reduction policies at the regional and national levels and induced significant changes in plastic waste management with potential for ne...
bioplastics;environmental sustainability;plastic pollution;plastic waste;sars-cov-2
Journal Article
Patricio Silva, Ana L;Prata, Joana C;Walker, Tony R;Campos, Diana;Duarte, Armando C;Soares, Amadeu M V M;Barcelo, Damia;Rocha-Santos, Teresa
10.1016/j.scitotenv.2020.140565
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Rethinking and optimising plastic waste management under COVID-19 pandemic: Policy solutions based on redesign and reduction of single-use plastics and personal protective equipment. [Abstract]: Plastics have been on top of the political agenda in Europe and across the world to reduce plastic leakage and pollu...
32,702,463
J Hosp Infect
Nosocomial COVID-19 infection: examining the risk of mortality. The COPE-Nosocomial Study (COVID in Older PEople).
BACKGROUND: Hospital admissions for non-coronavirus disease 2019 (COVID-19) pathology have decreased significantly. It is believed that this may be due to public anxiety about acquiring COVID-19 infection in hospital and the subsequent risk of mortality. AIM: To identify patients who acquire COVID-19 in hospital (nosoc...
covid-19;community-acquired infection;nosocomial infection
Comparative Study;Journal Article
Carter, B;Collins, J T;Barlow-Pay, F;Rickard, F;Bruce, E;Verduri, A;Quinn, T J;Mitchell, E;Price, A;Vilches-Moraga, A;Stechman, M J;Short, R;Einarsson, A;Braude, P;Moug, S;Myint, P K;Hewitt, J;Pearce, L;McCarthy, K
10.1016/j.jhin.2020.07.013
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Nosocomial COVID-19 infection: examining the risk of mortality. The COPE-Nosocomial Study (COVID in Older PEople). [Abstract]: BACKGROUND: Hospital admissions for non-coronavirus disease 2019 (COVID-19) pathology have decreased significantly. It is believed that this may be due to public anxiety about acquirin...
32,978,207
BMJ Open
Clinical risk score to predict in-hospital mortality in COVID-19 patients: a retrospective cohort study.
OBJECTIVES: Several physiological abnormalities that develop during COVID-19 are associated with increased mortality. In the present study, we aimed to develop a clinical risk score to predict the in-hospital mortality in COVID-19 patients, based on a set of variables available soon after the hospitalisation triage. SE...
covid-19;adult intensive & critical care;infectious diseases;internal medicine;public health
Journal Article
Fumagalli, Carlo;Rozzini, Renzo;Vannini, Matteo;Coccia, Flaminia;Cesaroni, Giulia;Mazzeo, Francesca;Cola, Maria;Bartoloni, Alessandro;Fontanari, Paolo;Lavorini, Federico;Marcucci, Rossella;Morettini, Alessandro;Nozzoli, Carlo;Peris, Adriano;Pieralli, Filippo;Pini, Riccardo;Poggesi, Loredana;Ungar, Andrea;Fumagalli, Ste...
10.1136/bmjopen-2020-040729
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical risk score to predict in-hospital mortality in COVID-19 patients: a retrospective cohort study. [Abstract]: OBJECTIVES: Several physiological abnormalities that develop during COVID-19 are associated with increased mortality. In the present study, we aimed to develop a clinical risk score to predict t...
32,548,750
J Neurovirol
The "Three Italy" of the COVID-19 epidemic and the possible involvement of SARS-CoV-2 in triggering complications other than pneumonia.
Coronavirus disease 2019 (COVID-19), first reported in Wuhan, the capital of Hubei, China, has been associated to a novel coronavirus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In March 2020, the World Health Organization declared the SARS-CoV-2 infection a global pandemic. Soon after, the numbe...
covid-19;cardiovascular manifestations;italy geographical circulation;neurological implications;pathophysiology;sars-cov-2
Journal Article;Research Support, Non-U.S. Gov't;Review
Prezioso, Carla;Marcocci, Maria Elena;Palamara, Anna Teresa;De Chiara, Giovanna;Pietropaolo, Valeria
10.1007/s13365-020-00862-z
[ 0, 1, 0, 1, 1, 0, 0 ]
[Title]: The "Three Italy" of the COVID-19 epidemic and the possible involvement of SARS-CoV-2 in triggering complications other than pneumonia. [Abstract]: Coronavirus disease 2019 (COVID-19), first reported in Wuhan, the capital of Hubei, China, has been associated to a novel coronavirus, the severe acute respiratory...
33,051,632
Aust J Gen Pract
Primary care for India's urban dwellers living in informal settlements during the COVID-19 pandemic: The experience of the Christian Medical College, Vellore, Department of Family Medicine.
COVID-19 disproportionally affects India's 81 million people living in urban informal settlements, where inadequate housing, water and sanitation increase the risk and rate of infection.
Journal Article
Abraham, Sunil;Gupta, Archna;Khare, Manorama
10.31128/AJGP-COVID-34
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Primary care for India's urban dwellers living in informal settlements during the COVID-19 pandemic: The experience of the Christian Medical College, Vellore, Department of Family Medicine. [Abstract]: COVID-19 disproportionally affects India's 81 million people living in urban informal settlements, where inad...
32,668,970
Am J Chin Med
Analysis of Traditional Chinese Medicine Diagnosis and Treatment Strategies for COVID-19 Based on "The Diagnosis and Treatment Program for Coronavirus Disease-2019" from Chinese Authority.
In December 2019, coronavirus disease-2019 (COVID-19) broke out in Wuhan and other places. Seven versions of the Diagnosis and Treatment Program for Coronavirus Disease-2019 successively issued by the Chinese government have designated traditional Chinese medicine (TCM) as a necessary medical strategy. Based on the cha...
covid-19;coronavirus disease-2019;diagnosis and treatment program for coronavirus disease-2019;qing fei pai du tang;review;traditional chinese medicine diagnosis and treatment strategies
Journal Article;Review
Zhao, Zhi-Hui;Zhou, Yi;Li, Wei-Hong;Huang, Qing-Song;Tang, Zhao-Hui;Li, Han
10.1142/S0192415X20500500
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Analysis of Traditional Chinese Medicine Diagnosis and Treatment Strategies for COVID-19 Based on "The Diagnosis and Treatment Program for Coronavirus Disease-2019" from Chinese Authority. [Abstract]: In December 2019, coronavirus disease-2019 (COVID-19) broke out in Wuhan and other places. Seven versions of t...
32,876,012
Am J Trop Med Hyg
Case Report: Adrenal Pathology Findings in Severe COVID-19: An Autopsy Study.
Although high mortality has been reported in many COVID-19 studies, very limited postmortem information from complete autopsies is available. We report the findings in the adrenal glands in 28 autopsies with confirmed SARS-CoV-2 infection. Microscopic lesions were identified in the adrenal glands in 12/28 patients (46%...
Case Reports;Journal Article
Freire Santana, Monique;Borba, Mayla Gabriela Silva;Baia-da-Silva, Djane Clarys;Val, Fernando;Alexandre, Marcia Almeida Araujo;Brito-Sousa, Jose Diego;Melo, Gisely Cardoso;Queiroga, Marcos Vinicius Oliveira;Leao Farias, Maria Eduarda;Camilo, Cecilia Cunha;Naveca, Felipe Gomes;Xavier, Mariana Simao;Monteiro, Wuelton Mar...
10.4269/ajtmh.20-0787
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Case Report: Adrenal Pathology Findings in Severe COVID-19: An Autopsy Study. [Abstract]: Although high mortality has been reported in many COVID-19 studies, very limited postmortem information from complete autopsies is available. We report the findings in the adrenal glands in 28 autopsies with confirmed SAR...
32,624,303
J Thorac Cardiovasc Surg
The rapid transformation of cardiac surgery practice in the coronavirus disease 2019 (COVID-19) pandemic: Insights and clinical strategies from a center at the epicenter.
BACKGROUND: The onset of the coronavirus disease 2019 (COVID-19) pandemic has forced our cardiac surgery program and hospital to enact drastic measures that has forced us to change how we care for cardiac surgery patients, assist with COVID-19 care, and enable support for the hospital in terms of physical resources, pr...
covid-19;new york;cardiac surgery;pandemic;reorganization
Journal Article
George, Isaac;Salna, Michael;Kobsa, Serge;Deroo, Scott;Kriegel, Jacob;Blitzer, David;Shea, Nicholas J;D'Angelo, Alex;Raza, Tasnim;Kurlansky, Paul;Takeda, Koji;Takayama, Hiroo;Bapat, Vinayak;Naka, Yoshifumi;Smith, Craig R;Bacha, Emile;Argenziano, Michael
10.1016/j.jtcvs.2020.04.060
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The rapid transformation of cardiac surgery practice in the coronavirus disease 2019 (COVID-19) pandemic: Insights and clinical strategies from a center at the epicenter. [Abstract]: BACKGROUND: The onset of the coronavirus disease 2019 (COVID-19) pandemic has forced our cardiac surgery program and hospital to...
32,895,747
Clin Rheumatol
Managing rheumatic diseases during COVID-19.
Rheumatology practice, during Coronavirus Disease 2019 (COVID-19) pandemic, has faced multifaceted challenges. Rheumatologists routinely prescribe immunosuppressant medications to their patients with multisystem autoimmune rheumatic diseases who are concerned about the increased risk of acquiring COVID-19 infection and...
autoimmune;covid-19;dmard;immunosuppressive;medications;rheumatic
Journal Article;Review
Ladani, Amit P;Loganathan, Muruga;Danve, Abhijeet
10.1007/s10067-020-05387-8
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Managing rheumatic diseases during COVID-19. [Abstract]: Rheumatology practice, during Coronavirus Disease 2019 (COVID-19) pandemic, has faced multifaceted challenges. Rheumatologists routinely prescribe immunosuppressant medications to their patients with multisystem autoimmune rheumatic diseases who are conc...
32,360,608
Prog Biophys Mol Biol
Forecasting the timeframe of 2019-nCoV and human cells interaction with reverse engineering.
In December 2019, an atypical pneumonia invaded the city of Wuhan, China, and the causative agent of this disease turned out to be a new coronavirus. In January 2020, the World Health Organization named the new coronavirus 2019-nCoV and subsequently it is referred to as SARS-CoV2 and the related disease as CoViD-19 (La...
dynamical analysis;kinetic modelling;mcmc analysis;monoclonal antibody;numerical simulations;sars-cov2
Journal Article;Research Support, Non-U.S. Gov't;Review
Sohail, Ayesha;Nutini, Alessandro
10.1016/j.pbiomolbio.2020.04.002
[ 1, 0, 1, 1, 0, 0, 0 ]
[Title]: Forecasting the timeframe of 2019-nCoV and human cells interaction with reverse engineering. [Abstract]: In December 2019, an atypical pneumonia invaded the city of Wuhan, China, and the causative agent of this disease turned out to be a new coronavirus. In January 2020, the World Health Organization named the...
32,259,313
Pharmacotherapy
Review of Emerging Pharmacotherapy for the Treatment of Coronavirus Disease 2019.
The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved into an emergent global pandemic. Coronavirus disease 2019 (COVID-19) can manifest on a spectrum of illness from mild disease to severe respiratory failure requiring intensive care unit admission. As the incidence continues to rise...
antivirals;cytochrome p450;dialysis;infectious disease;liver;renal
Journal Article;Review
Barlow, Ashley;Landolf, Kaitlin M;Barlow, Brooke;Yeung, Siu Yan Amy;Heavner, Jason J;Claassen, Cassidy W;Heavner, Mojdeh S
10.1002/phar.2398
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Review of Emerging Pharmacotherapy for the Treatment of Coronavirus Disease 2019. [Abstract]: The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved into an emergent global pandemic. Coronavirus disease 2019 (COVID-19) can manifest on a spectrum of illness from mild disease to...
32,680,896
Cleve Clin J Med
Evaluation and management of shock in patients with COVID-19.
Shock is common in critically ill patients with COVID-19, developing in up to 67% of patients in intensive care (5% to 10% overall) and is associated with high mortality. Optimal management requires prompt recognition with precise evaluation and differentiation. Correcting hypoperfusion and treating the underlying proc...
Journal Article
Fox, Steven;Vashisht, Rishik;Siuba, Matthew;Dugar, Siddharth
10.3949/ccjm.87a.ccc052
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Evaluation and management of shock in patients with COVID-19. [Abstract]: Shock is common in critically ill patients with COVID-19, developing in up to 67% of patients in intensive care (5% to 10% overall) and is associated with high mortality. Optimal management requires prompt recognition with precise evalua...
32,923,679
Transl Med Commun
C-C chemokine receptor type 5 links COVID-19, rheumatoid arthritis, and Hydroxychloroquine: in silico analysis.
Patients with rheumatoid arthritis (RA) represent one of the fragile patient groups that might be susceptible to the critical form of the coronavirus disease - 19 (COVID-19). On the other side, RA patients have been found not to have an increased risk of COVID-19 infection. Moreover, some of the Disease-Modifying Anti-...
Journal Article
Hachim, Mahmood Y;Hachim, Ibrahim Y;Naeem, Kashif Bin;Hannawi, Haifa;Al Salmi, Issa;Hannawi, Suad
10.1186/s41231-020-00066-x
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: C-C chemokine receptor type 5 links COVID-19, rheumatoid arthritis, and Hydroxychloroquine: in silico analysis. [Abstract]: Patients with rheumatoid arthritis (RA) represent one of the fragile patient groups that might be susceptible to the critical form of the coronavirus disease - 19 (COVID-19). On the other...
32,475,088
Intest Res
Patterns of endoscopy during COVID-19 pandemic: a global survey of interventional inflammatory bowel disease practice.
Background/Aims: Performance of diagnostic or therapeutic endoscopic procedures in inflammatory bowel disease (IBD) patients can be challenging during a viral pandemic; the main concerns being the safety and protection of patients and health care providers (HCP). The aim of this study is to identify endoscopic practice...
covid-19;crohn disease;endoscopy;inflammatory bowel disease;ulcerative colitis
Journal Article
Chen, Yan;Yu, Qiao;Farraye, Francis A;Kochhar, Gursimran S;Bernstein, Charles N;Navaneethan, Udayakumar;Wu, Kaicun;Zhong, Jie;Schwartz, David A;Wu, Hao;Zheng, Jing-Jing;Iacucci, Marietta;Kiran, Ravi P;Shen, Bo
10.5217/ir.2020.00037
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Patterns of endoscopy during COVID-19 pandemic: a global survey of interventional inflammatory bowel disease practice. [Abstract]: Background/Aims: Performance of diagnostic or therapeutic endoscopic procedures in inflammatory bowel disease (IBD) patients can be challenging during a viral pandemic; the main co...
32,567,057
Int Nurs Rev
COVID-19 pandemic in France: health emergency experiences from the field.
AIM: This paper describes the situation regarding COVID-19 emergency in France as of early May 2020, the main policies to fight this virus, and the roles and responsibilities of nurses regarding their work at this time, as well as the challenges facing the profession. BACKGROUND: Europe continues to be affected by the ...
covid-19;france;health emergency;health policy;nursing nursing policy;pandemics primary care nursing;public health;roles and responsibilities
Journal Article
Chamboredon, P;Roman, C;Colson, S
10.1111/inr.12604
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 pandemic in France: health emergency experiences from the field. [Abstract]: AIM: This paper describes the situation regarding COVID-19 emergency in France as of early May 2020, the main policies to fight this virus, and the roles and responsibilities of nurses regarding their work at this time, as we...
32,220,655
Lancet Public Health
The effect of control strategies to reduce social mixing on outcomes of the COVID-19 epidemic in Wuhan, China: a modelling study.
BACKGROUND: In December, 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus, emerged in Wuhan, China. Since then, the city of Wuhan has taken unprecedented measures in response to the outbreak, including extended school and workplace closures. We aimed to estimate the effects of phy...
Journal Article;Research Support, Non-U.S. Gov't
Prem, Kiesha;Liu, Yang;Russell, Timothy W;Kucharski, Adam J;Eggo, Rosalind M;Davies, Nicholas;Jit, Mark;Klepac, Petra
10.1016/S2468-2667(20)30073-6
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The effect of control strategies to reduce social mixing on outcomes of the COVID-19 epidemic in Wuhan, China: a modelling study. [Abstract]: BACKGROUND: In December, 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus, emerged in Wuhan, China. Since then, the city of Wuhan ...
33,060,700
Sci Rep
Retinal involvement and ocular findings in COVID-19 pneumonia patients.
Changes in immune and coagulation systems and possible viral spread through the blood-brain barrier have been described in SARS-CoV-2 infection. In this study, we evaluated the possible retinal involvement and ocular findings in severe COVID-19 pneumonia patients. A cross-sectional study was conducted on 46 patients af...
Journal Article
Pirraglia, Maria Pia;Ceccarelli, Giancarlo;Cerini, Alberto;Visioli, Giacomo;d'Ettorre, Gabriella;Mastroianni, Claudio M;Pugliese, Francesco;Lambiase, Alessandro;Gharbiya, Magda
10.1038/s41598-020-74446-6
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Retinal involvement and ocular findings in COVID-19 pneumonia patients. [Abstract]: Changes in immune and coagulation systems and possible viral spread through the blood-brain barrier have been described in SARS-CoV-2 infection. In this study, we evaluated the possible retinal involvement and ocular findings i...
32,520,743
Ann Surg
Outcomes of Elective Major Cancer Surgery During COVID 19 at Tata Memorial Centre: Implications for Cancer Care Policy.
BACKGROUND: Overburdened systems and concerns of adverse outcomes have resulted in deferred cancer surgeries with devastating consequences. In this COVID pandemic, the decision to continue elective cancer surgeries, and their subsequent outcomes, are sparsely reported from hotspots. METHODS: A prospective database of t...
Journal Article
Shrikhande, Shailesh V;Pai, Prathmesh S;Bhandare, Manish S;Bakshi, Ganesh;Chaukar, Devendra A;Chaturvedi, Pankaj;Goel, Mahesh;Gulia, Ashish;Qureshi, Sajid S;Maheshwari, Amita;Moiyadi, Aliasgar;Nair, Sudhir;Nair, Nita S;Karimundackal, George;Saklani, Avanish P;Shankhadhar, Vinay K;Parmar, Vani;Divatia, Jigeeshu V;Prames...
10.1097/SLA.0000000000004116
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Outcomes of Elective Major Cancer Surgery During COVID 19 at Tata Memorial Centre: Implications for Cancer Care Policy. [Abstract]: BACKGROUND: Overburdened systems and concerns of adverse outcomes have resulted in deferred cancer surgeries with devastating consequences. In this COVID pandemic, the decision to...
33,025,310
Egypt Heart J
Clinical and angiographic characteristics of patients with STEMI and confirmed diagnosis of COVID-19: an experience of Tanta University Hospital.
BACKGROUND: Patients with established cardiovascular diseases have a poor prognosis when affected by the coronavirus disease 2019 (COVID-19). Also, the cardiovascular system, especially the heart, is affected by COVID-19. So we aimed to evaluate the angiographic and clinical characteristics of COVID-19 patients present...
covid-19;high thrombus burden;primary pci;stemi;timi flow
Journal Article
Alaarag, Ahmed;Hassan, Timoor;Samir, Sameh;Naseem, Mohamed
10.1186/s43044-020-00103-y
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical and angiographic characteristics of patients with STEMI and confirmed diagnosis of COVID-19: an experience of Tanta University Hospital. [Abstract]: BACKGROUND: Patients with established cardiovascular diseases have a poor prognosis when affected by the coronavirus disease 2019 (COVID-19). Also, the c...
32,344,809
Int J Environ Res Public Health
Psychological and Behavioral Responses in South Korea During the Early Stages of Coronavirus Disease 2019 (COVID-19).
Background: The psychological and behavioral responses during the early stage of Coronavirus disease 2019 (COVID-19) in South Korea were investigated to guide the public as full and active participants of public health emergency preparedness (PHEP), which is essential to improving resilience and reducing the population...
coronavirus;efficacy belief;pandemics;perceived risk;precautionary behaviors;public health emergency preparedness
Journal Article;Research Support, Non-U.S. Gov't
Lee, Minjung;You, Myoungsoon
10.3390/ijerph17092977
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Psychological and Behavioral Responses in South Korea During the Early Stages of Coronavirus Disease 2019 (COVID-19). [Abstract]: Background: The psychological and behavioral responses during the early stage of Coronavirus disease 2019 (COVID-19) in South Korea were investigated to guide the public as full and...
32,524,537
Acta Neurol Belg
A complication of coronavirus disease 2019: delirium.
COVID-19 is predominantly a respiratory disease. However, some cases exhibit other features including Central Nervous System symptoms. In the older adult, COVID-19 may present with atypical symptoms, including delirium and its complications. The objective of this study is to describe the relationship between the new ty...
covid-19;delirium;dementia;intensive-care unit
Journal Article;Systematic Review
Cipriani, Gabriele;Danti, Sabrina;Nuti, Angelo;Carlesi, Cecilia;Lucetti, Claudio;Di Fiorino, Mario
10.1007/s13760-020-01401-7
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A complication of coronavirus disease 2019: delirium. [Abstract]: COVID-19 is predominantly a respiratory disease. However, some cases exhibit other features including Central Nervous System symptoms. In the older adult, COVID-19 may present with atypical symptoms, including delirium and its complications. The...
32,314,483
Dermatol Ther
COVID-19 and psoriasis: Should we fear for patients treated with biologics?
The new coronavirus pandemic poses question and challenges for dermatologists. One of question is if psoriasis patients treated with immunomodulating and immunosuppressive drugs have to discontinue their treatment in the midst of fears for the infection and its consequences. One of the challenges is how can we support ...
covid-19;sars;biologics;psoriasis;therapy
Journal Article;Review
Amerio, Paolo;Prignano, Francesca;Giuliani, Federica;Gualdi, Giulio
10.1111/dth.13434
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 and psoriasis: Should we fear for patients treated with biologics? [Abstract]: The new coronavirus pandemic poses question and challenges for dermatologists. One of question is if psoriasis patients treated with immunomodulating and immunosuppressive drugs have to discontinue their treatment in the mi...
32,466,862
Acta Otorrinolaringol Esp
[Olfactory dysfunction in COVID-19, a review of the evidence and implications for pandemic management].
There is debate as to whether olfactory dysfunction should be considered a symptom of COVID-19 infection. We undertook a systematic literature review of the articles indexed in PubMed on olfactory disorders in viral respiratory tract conditions, with special emphasis on COVID-19. The main objective was to find evidence...
anosmia;covid 19;post-viral olfactory dysfunction
Journal Article;Systematic Review
Lop Gros, Joan;Iglesias Coma, Mar;Gonzalez Farre, Monica;Serra Pujadas, Consol
10.1016/j.otorri.2020.04.003
[ 1, 1, 1, 0, 0, 0, 0 ]
[Title]: [Olfactory dysfunction in COVID-19, a review of the evidence and implications for pandemic management]. [Abstract]: There is debate as to whether olfactory dysfunction should be considered a symptom of COVID-19 infection. We undertook a systematic literature review of the articles indexed in PubMed on olfactor...
32,546,029
Immunotherapy
Case report: use of lenzilumab and tocilizumab for the treatment of coronavirus disease 2019.
Background: Coronavirus disease 2019 (COVID-19) is a novel disease associated with a cytokine-mediated, severe, acute respiratory syndrome. Tocilizumab and lenzilumab are recombinant monoclonal antibodies against IL-6 and granulocyte macrophage colony-stimulating factor, respectively, and have been proposed as a potent...
covid-19;gm-csf;il-6;cytokine-release syndrome;inflammatory markers;lenzilumab;monoclonal antibody;pneumonia;severe acute respiratory distress syndrome;tocilizumab
Case Reports;Journal Article
Melody, Megan;Nelson, Jared;Hastings, Jacquelyn;Propst, Joshua;Smerina, Michael;Mendez, Julio;Guru, Pramod
10.2217/imt-2020-0136
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Case report: use of lenzilumab and tocilizumab for the treatment of coronavirus disease 2019. [Abstract]: Background: Coronavirus disease 2019 (COVID-19) is a novel disease associated with a cytokine-mediated, severe, acute respiratory syndrome. Tocilizumab and lenzilumab are recombinant monoclonal antibodies ...
32,823,775
Int J Environ Res Public Health
Key Guidelines in Developing a Pre-Emptive COVID-19 Vaccination Uptake Promotion Strategy.
This paper makes the case for immediate planning for a COVID-19 vaccination uptake strategy in advance of vaccine availability for two reasons: first, the need to build a consensus about the order in which groups of the population will get access to the vaccine; second, to reduce any fear and concerns that exist in rel...
covid-19;behaviour change;communication;social marketing;vaccine hesitancy;vaccine uptake
Journal Article;Review
French, Jeff;Deshpande, Sameer;Evans, William;Obregon, Rafael
10.3390/ijerph17165893
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Key Guidelines in Developing a Pre-Emptive COVID-19 Vaccination Uptake Promotion Strategy. [Abstract]: This paper makes the case for immediate planning for a COVID-19 vaccination uptake strategy in advance of vaccine availability for two reasons: first, the need to build a consensus about the order in which gr...
32,568,618
J Biomol Struct Dyn
Chemical-informatics approach to COVID-19 drug discovery: Monte Carlo based QSAR, virtual screening and molecular docking study of some in-house molecules as papain-like protease (PLpro) inhibitors.
World Health Organization characterized novel coronavirus disease (COVID-19), caused by severe acute respiratory syndrome (SARS) coronavirus-2 (SARS-CoV-2) as world pandemic. This infection has been spreading alarmingly by causing huge social and economic disruption. In order to response quickly, the inhibitors already...
adme;covid-19;monte carlo based optimization;qsar based virtual screening;sars-cov plpro;sars-cov-2;molecular docking
Journal Article
Amin, Sk Abdul;Ghosh, Kalyan;Gayen, Shovanlal;Jha, Tarun
10.1080/07391102.2020.1780946
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Chemical-informatics approach to COVID-19 drug discovery: Monte Carlo based QSAR, virtual screening and molecular docking study of some in-house molecules as papain-like protease (PLpro) inhibitors. [Abstract]: World Health Organization characterized novel coronavirus disease (COVID-19), caused by severe acute...
32,921,934
Chaos Solitons Fractals
CVDNet: A novel deep learning architecture for detection of coronavirus (Covid-19) from chest x-ray images.
The COVID-19 pandemic is an emerging respiratory infectious disease, also known as coronavirus 2019. It appears in November 2019 in Hubei province (in China), and more specifically in the city of Wuhan, then spreads in the whole world. As the number of cases increases with unprecedented speed, many parts of the world a...
covid-19;chest x-ray images;classification;convolutional neural network;coronavirus;deep learning
Journal Article
Ouchicha, Chaimae;Ammor, Ouafae;Meknassi, Mohammed
10.1016/j.chaos.2020.110245
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: CVDNet: A novel deep learning architecture for detection of coronavirus (Covid-19) from chest x-ray images. [Abstract]: The COVID-19 pandemic is an emerging respiratory infectious disease, also known as coronavirus 2019. It appears in November 2019 in Hubei province (in China), and more specifically in the cit...
32,533,263
AAPS J
Intracellular ABCB1 as a Possible Mechanism to Explain the Synergistic Effect of Hydroxychloroquine-Azithromycin Combination in COVID-19 Therapy.
The co-administration of hydroxychloroquine with azithromycin is proposed in COVID-19 therapy. We hypothesize a new mechanism supporting the synergistic interaction between these drugs. Azithromycin is a substrate of ABCB1 (P-glycoprotein) which is localized in endosomes and lysosomes with a polarized substrate transpo...
abcb1;covid-19;azithromycin;hydroxychloroquine;lysosomes
Journal Article
Scherrmann, J M
10.1208/s12248-020-00465-w
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Intracellular ABCB1 as a Possible Mechanism to Explain the Synergistic Effect of Hydroxychloroquine-Azithromycin Combination in COVID-19 Therapy. [Abstract]: The co-administration of hydroxychloroquine with azithromycin is proposed in COVID-19 therapy. We hypothesize a new mechanism supporting the synergistic ...
32,728,654
J Endocr Soc
The Impact of SARS-Cov-2 Virus Infection on the Endocrine System.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus has spread across the globe rapidly causing an unprecedented pandemic. Because of the novelty of the disease, the possible impact on the endocrine system is not clear. To compile a mini-review describing possible endocrine consequences of SARS-CoV-2 inf...
covid-19;endocrine;sars-cov2
Journal Article;Review
Somasundaram, Noel Pratheepan;Ranathunga, Ishara;Ratnasamy, Vithiya;Wijewickrama, Piyumi Sachindra Alwis;Dissanayake, Harsha Anuruddhika;Yogendranathan, Nilukshana;Gamage, Kavinga Kalhari Kobawaka;de Silva, Nipun Lakshitha;Sumanatilleke, Manilka;Katulanda, Prasad;Grossman, Ashley Barry
10.1210/jendso/bvaa082
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: The Impact of SARS-Cov-2 Virus Infection on the Endocrine System. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus has spread across the globe rapidly causing an unprecedented pandemic. Because of the novelty of the disease, the possible impact on the endocrine system is not clear...
32,540,844
J Med Internet Res
Mapping of Health Literacy and Social Panic Via Web Search Data During the COVID-19 Public Health Emergency: Infodemiological Study.
BACKGROUND: Coronavirus disease (COVID-19) is a type of pneumonia caused by a novel coronavirus that was discovered in 2019. As of May 6, 2020, 84,407 cases and 4643 deaths have been confirmed in China. The Chinese population has expressed great concern since the COVID-19 outbreak. Meanwhile, an average of 1 billion pe...
baidu;covid-19;china;emergency;health literacy;infectious disease;infodemiology;internet;outbreak;pandemic;public health;web search
Journal Article
Xu, Chenjie;Zhang, Xinyu;Wang, Yaogang
10.2196/18831
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Mapping of Health Literacy and Social Panic Via Web Search Data During the COVID-19 Public Health Emergency: Infodemiological Study. [Abstract]: BACKGROUND: Coronavirus disease (COVID-19) is a type of pneumonia caused by a novel coronavirus that was discovered in 2019. As of May 6, 2020, 84,407 cases and 4643 ...
32,922,853
BJR Case Rep
Unusual lesion in the splenium of the corpus callosum and coronavirus infectious disease-19.
Coronavirus infectious diseases (COVID-19) is an emerging infectious disease that has taken a strong grip on the entire global community. The diagnosis per se is straightforward; however, the disease seems to affect multiple organs. Cytokine-storm, increased thromboembolic state, deranged overall homeostasis and aggres...
Case Reports
Agarwal, Nivedita;Martini, Rosella;Pedrotti, Giovanni;Della Sala, Sabino Walter
10.1259/bjrcr.20200068
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Unusual lesion in the splenium of the corpus callosum and coronavirus infectious disease-19. [Abstract]: Coronavirus infectious diseases (COVID-19) is an emerging infectious disease that has taken a strong grip on the entire global community. The diagnosis per se is straightforward; however, the disease seems ...
32,436,481
CJEM
Hazard control for communicable disease transport at Ornge.
Transporting patients with communicable diseases is common in critical care transport operations. At Ornge, Ontario's critical care transport provider, 13.7% of patients required contact, droplet, or airborne precautions during transport in 2019-2020. Ensuring that staff are protected while transporting patients with c...
aeromedical transport;covid-19;communicable disease;hazard control;personal protective equipment
Journal Article
Peddle, Michael B;Smith, Justin A
10.1017/cem.2020.399
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Hazard control for communicable disease transport at Ornge. [Abstract]: Transporting patients with communicable diseases is common in critical care transport operations. At Ornge, Ontario's critical care transport provider, 13.7% of patients required contact, droplet, or airborne precautions during transport i...
32,314,249
Obes Surg
Bariatric Surgical Practice During the Initial Phase of COVID-19 Outbreak.
There is no data on patients with severe obesity who developed coronavirus disease 2019 (COVID-19) after bariatric surgery. Four gastric bypass operations, performed in a 2-week period between Feb 24 and March 4, 2020, in Tehran, Iran, were complicated with COVID-19. The mean age and body mass index were 46 +/- 12 year...
bariatric surgery;covid-19;complications;coronavirus;gastric bypass;pneumonia
Journal Article
Aminian, Ali;Kermansaravi, Mohammad;Azizi, Shahriar;Alibeigi, Peyman;Safamanesh, Sina;Mousavimaleki, Ali;Rezaei, Mohammad Taghi;Faridi, Maziar;Mokhber, Somayeh;Pazouki, Abdolreza;Safari, Saeed
10.1007/s11695-020-04617-x
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Bariatric Surgical Practice During the Initial Phase of COVID-19 Outbreak. [Abstract]: There is no data on patients with severe obesity who developed coronavirus disease 2019 (COVID-19) after bariatric surgery. Four gastric bypass operations, performed in a 2-week period between Feb 24 and March 4, 2020, in Te...
32,566,261
NPJ Vaccines
Applying lessons from the Ebola vaccine experience for SARS-CoV-2 and other epidemic pathogens.
The world is experiencing an unprecedented global pandemic of coronavirus disease 2019 (COVID-19) caused by a novel coronavirus, Severe Acute Respiratory Syndrome-coronavirus-2 (SARS-CoV-2). Development of new vaccines and therapeutics are important to achieve long-term prevention and control of the virus. Experience g...
drug development;drug regulation
Journal Article;Review
Wolf, Jayanthi;Bruno, Samantha;Eichberg, Michael;Jannat, Risat;Rudo, Sharon;VanRheenen, Susan;Coller, Beth-Ann
10.1038/s41541-020-0204-7
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Applying lessons from the Ebola vaccine experience for SARS-CoV-2 and other epidemic pathogens. [Abstract]: The world is experiencing an unprecedented global pandemic of coronavirus disease 2019 (COVID-19) caused by a novel coronavirus, Severe Acute Respiratory Syndrome-coronavirus-2 (SARS-CoV-2). Development ...
33,011,993
Fundam Clin Pharmacol
Antiviral therapies: advances and perspectives.
Viral infections cause high morbidity and mortality, threaten public health, and impose a socioeconomic burden. We have seen the recent emergence of SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), the causative agent of COVID-19 that has already infected more than 29 million people, with more than 900 000...
crispr-cas;antivirals;monoclonal antibodies;nanoparticles
Journal Article;Review
Goncalves, Bruna Carolina;Lopes Barbosa, Mario Gabriel;Silva Olak, Anna Paula;Belebecha Terezo, Natalia;Nishi, Leticia;Watanabe, Maria Angelica;Marinello, Poliana;Zendrini Rechenchoski, Daniele;Dejato Rocha, Sergio Paulo;Faccin-Galhardi, Ligia Carla
10.1111/fcp.12609
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Antiviral therapies: advances and perspectives. [Abstract]: Viral infections cause high morbidity and mortality, threaten public health, and impose a socioeconomic burden. We have seen the recent emergence of SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), the causative agent of COVID-19 that has...
32,376,901
Nat Rev Immunol
Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages.
The COVID-19 pandemic caused by infection with SARS-CoV-2 has led to more than 200,000 deaths worldwide. Several studies have now established that the hyperinflammatory response induced by SARS-CoV-2 is a major cause of disease severity and death in infected patients. Macrophages are a population of innate immune cells...
Journal Article;Review
Merad, Miriam;Martin, Jerome C
10.1038/s41577-020-0331-4
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages. [Abstract]: The COVID-19 pandemic caused by infection with SARS-CoV-2 has led to more than 200,000 deaths worldwide. Several studies have now established that the hyperinflammatory response induced by SARS-CoV-2 is a...
32,426,062
Diabetes Metab Syndr
Impact of complete lockdown on total infection and death rates: A hierarchical cluster analysis.
INTRODUCTION AND AIMS: Retarding the spread of SARS-CoV-2 infection by preventive strategies is the first line of management. Several countries have declared a stringent lockdown in order to enforce social distancing and prevent the spread of infection. This analysis was conducted in an attempt to understand the impact...
cluster analysis;death;infection;lockdown;sars-cov-2
Journal Article
Ghosal, Samit;Bhattacharyya, Rahul;Majumder, Milan
10.1016/j.dsx.2020.05.026
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of complete lockdown on total infection and death rates: A hierarchical cluster analysis. [Abstract]: INTRODUCTION AND AIMS: Retarding the spread of SARS-CoV-2 infection by preventive strategies is the first line of management. Several countries have declared a stringent lockdown in order to enforce soc...
32,461,502
Tohoku J Exp Med
COVID-19 Waves: Importance of Accumulative Mortality per Million Inhabitants.
The reported number of new cases underestimates the real spread of COVID-19 pandemic because of non-tested asymptomatic people and limited global access to reliable diagnostic tests. In this context, COVID-19 mortality with confirmed diagnosis becomes an attractive source of information to be included in the analysis o...
covid-19;mortality;pandemics;public health;registries
Journal Article
Delgado, Carlos A;Shimabuku, Roberto L;Chiroque-Solano, Pamela M
10.1620/tjem.251.47
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: COVID-19 Waves: Importance of Accumulative Mortality per Million Inhabitants. [Abstract]: The reported number of new cases underestimates the real spread of COVID-19 pandemic because of non-tested asymptomatic people and limited global access to reliable diagnostic tests. In this context, COVID-19 mortality wi...
32,179,908
J Infect Dis
A 55-Day-Old Female Infant Infected With 2019 Novel Coronavirus Disease: Presenting With Pneumonia, Liver Injury, and Heart Damage.
BACKGROUND: Previous studies on the pneumonia outbreak caused by the 2019 novel coronavirus disease (COVID-19) were mainly based on information from adult populations. Limited data are available for children with COVID-19, especially for infected infants. METHODS: We report a 55-day-old case with COVID-19 confirmed in ...
covid-19 pneumonia;heart damage;liver injury
Case Reports;Journal Article;Research Support, Non-U.S. Gov't
Cui, Yuxia;Tian, Maolu;Huang, Dong;Wang, Xike;Huang, Yuying;Fan, Li;Wang, Liang;Chen, Yun;Liu, Wenpu;Zhang, Kai;Wu, Yue;Yang, Zhenzhong;Tao, Jing;Feng, Jie;Liu, Kaiyu;Ye, Xianwei;Wang, Rongpin;Zhang, Xiangyan;Zha, Yan
10.1093/infdis/jiaa113
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: A 55-Day-Old Female Infant Infected With 2019 Novel Coronavirus Disease: Presenting With Pneumonia, Liver Injury, and Heart Damage. [Abstract]: BACKGROUND: Previous studies on the pneumonia outbreak caused by the 2019 novel coronavirus disease (COVID-19) were mainly based on information from adult populations....
32,883,925
Indian J Med Microbiol
Healthcare facilities in low- and middle-income countries affected by COVID-19: Time to upgrade basic infection control and prevention practices.
COVID-19 as a pandemic has spanned across all continents. With the increasing numbers in cases worldwide, even the countries with the best of healthcare facilities are reeling under the burden of the disease. Therefore, in countries with limited access to resources and poor healthcare infrastructure, the low and middle...
covid-19;hand hygiene;low and middle income;personal protective equipment
Journal Article;Review
Angrup, Archana;Kanaujia, Rimjhim;Ray, Pallab;Biswal, Manisha
10.4103/ijmm.IJMM_20_125
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Healthcare facilities in low- and middle-income countries affected by COVID-19: Time to upgrade basic infection control and prevention practices. [Abstract]: COVID-19 as a pandemic has spanned across all continents. With the increasing numbers in cases worldwide, even the countries with the best of healthcare ...
32,983,936
Bioimpacts
Effect of bromhexine on clinical outcomes and mortality in COVID-19 patients: A randomized clinical trial.
Introduction: Bromhexine is a potential therapeutic option in COVID-19, but no data from a randomized clinical trial has been available. The present study aimed to evaluate the efficacy of bromhexine in intensive care unit (ICU) admission, mechanical ventilation, and mortality in patients with COVID-19. Methods: An ope...
bromhexine hydrochloride;covid-19 disease;covid-19 pneumonia;covid-19 treatment;sars-cov2;tmprss2
Journal Article
Ansarin, Khalil;Tolouian, Ramin;Ardalan, Mohammadreza;Taghizadieh, Ali;Varshochi, Mojtaba;Teimouri, Soheil;Vaezi, Tahere;Valizadeh, Hamed;Saleh, Parviz;Safiri, Saeid;Chapman, Kenneth R
10.34172/bi.2020.27
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Effect of bromhexine on clinical outcomes and mortality in COVID-19 patients: A randomized clinical trial. [Abstract]: Introduction: Bromhexine is a potential therapeutic option in COVID-19, but no data from a randomized clinical trial has been available. The present study aimed to evaluate the efficacy of bro...
33,034,824
Protein J
Perspective on the Role of Antibodies and Potential Therapeutic Drugs to Combat COVID-19.
The sudden emergence of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing the coronavirus disease of 2019 (COVID-19) has brought the world to a standstill. Thousands of people across the globe are biting the dust with every passing day and yet more are being tested positive for the SARS-CoV...
antibody;covid-19;convalescent plasma;cytokine;sars-cov-2;therapeutic drug
Journal Article;Review
Tandon, Siddhi;Aggarwal, Anchal;Jain, Shubhra;Shukla, Sanjay;Chaudhary, Sarika
10.1007/s10930-020-09921-0
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Perspective on the Role of Antibodies and Potential Therapeutic Drugs to Combat COVID-19. [Abstract]: The sudden emergence of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing the coronavirus disease of 2019 (COVID-19) has brought the world to a standstill. Thousands of people acro...
32,834,655
Chaos Solitons Fractals
Mathematical model of Ebola and Covid-19 with fractional differential operators: Non-Markovian process and class for virus pathogen in the environment.
Differential operators based on convolution definitions have been recognized as powerful mathematics tools to help model real world problems due to the properties associated to their different kernels. In particular the power law kernel helps include into mathematical formulation the effect of long range, while the exp...
covid-19 and ebola model;fractional calculus;new fractional kernels;new numerical scheme based on lagrange interpolation
Journal Article
Zhang, Zizhen;Jain, Sonal
10.1016/j.chaos.2020.110175
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Mathematical model of Ebola and Covid-19 with fractional differential operators: Non-Markovian process and class for virus pathogen in the environment. [Abstract]: Differential operators based on convolution definitions have been recognized as powerful mathematics tools to help model real world problems due to...
33,015,712
Am J Clin Pathol
A Comparison of Five SARS-CoV-2 Molecular Assays With Clinical Correlations.
OBJECTIVES: Comparative assessments of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) molecular assays that have been operationalized through the US Food and Drug Administration's Emergency Use Authorization process are warranted to assess real-world performance. Characteristics such as sensitivity, speci...
covid-19;coronavirus;nucleic acid amplification tests;sars-cov-2
Comparative Study;Journal Article
Procop, Gary W;Brock, Jay E;Reineks, Edmunds Z;Shrestha, Nabin K;Demkowicz, Ryan;Cook, Eleanor;Ababneh, Emad;Harrington, Susan M
10.1093/ajcp/aqaa181
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: A Comparison of Five SARS-CoV-2 Molecular Assays With Clinical Correlations. [Abstract]: OBJECTIVES: Comparative assessments of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) molecular assays that have been operationalized through the US Food and Drug Administration's Emergency Use Authorization ...
32,903,640
Front Physiol
Comorbidity Assessment Is Essential During COVID-19 Treatment.
Coronavirus disease 2019 (COVID-19) caused by SARS-CoV2 is associated with various comorbidities; cardiovascular diseases, hypertension, diabetes, liver, lung diseases, and neurological ailments. The majority of the dysfunctions mentioned above are often associated with endothelial deterioration, indicating that endoth...
covid-19;sars-cov2;comorbidities;diabetes;heart disease;hypertension;medications;mortality
Journal Article
Jakhmola, Shweta;Indari, Omkar;Baral, Budhadev;Kashyap, Dharmendra;Varshney, Nidhi;Das, Ayan;Chatterjee, Sayantani;Jha, Hem Chandra
10.3389/fphys.2020.00984
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Comorbidity Assessment Is Essential During COVID-19 Treatment. [Abstract]: Coronavirus disease 2019 (COVID-19) caused by SARS-CoV2 is associated with various comorbidities; cardiovascular diseases, hypertension, diabetes, liver, lung diseases, and neurological ailments. The majority of the dysfunctions mention...
32,989,416
Clin Transl Imaging
Surveys on COVID-19 in nuclear medicine: what happened and what we learned.
Introduction: To summarize and comment the available surveys on the impact of COVID-19 on Nuclear Medicine (NM) departments. Methods: Recent surveys about the impact of COVID-19 on Nuclear Medicine (NM) departments have been searched on available scientific database. Results: Three surveys have been found and commented...
covid;nuclear medicine;survey
Journal Article;Review
Annunziata, Salvatore;Albano, Domenico;Laudicella, Riccardo;Bauckneht, Matteo
10.1007/s40336-020-00391-z
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Surveys on COVID-19 in nuclear medicine: what happened and what we learned. [Abstract]: Introduction: To summarize and comment the available surveys on the impact of COVID-19 on Nuclear Medicine (NM) departments. Methods: Recent surveys about the impact of COVID-19 on Nuclear Medicine (NM) departments have bee...
32,905,189
Chin Med
Reflections on treatment of COVID-19 with traditional Chinese medicine.
Coronavirus disease 2019 (COVID-19) pandemic is spreading rapidly around the globe. By the establishment of an integrative system combining both traditional Chinese medicine (TCM) and western medicine, China has achieved good clinical efficacy in the prevention and control of the pandemic. The advantages of TCM in the ...
covid-19;coronavirus;prescriptions;traditional chinese medicine
Journal Article;Review
Luo, Hua;Gao, Yan;Zou, Jian;Zhang, Siyuan;Chen, Hanbin;Liu, Qiao;Tan, Dechao;Han, Yan;Zhao, Yonghua;Wang, Shengpeng
10.1186/s13020-020-00375-1
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Reflections on treatment of COVID-19 with traditional Chinese medicine. [Abstract]: Coronavirus disease 2019 (COVID-19) pandemic is spreading rapidly around the globe. By the establishment of an integrative system combining both traditional Chinese medicine (TCM) and western medicine, China has achieved good c...
32,621,492
East Mediterr Health J
Leveraging the COVID-19 response to improve emergency care systems in the Eastern Mediterranean Region.
The COVID-19 pandemic began as a cluster of reported cases of acute respiratory illness in China on 31 December 2019 and went on to spread with exponential growth across the globe. By the time it was characterized as a global pandemic on 11 March 2020, 17 of 22 countries in the Eastern Mediterranean Region (EMR) had re...
Editorial
Mowafi, Hani;Sakr, Hala;Ravaghi, Hamid;Elmahal, Osman;Slama, Slim;Samhouri, Dalia;Relan, Pryanka
10.26719/2020.26.6.626
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Leveraging the COVID-19 response to improve emergency care systems in the Eastern Mediterranean Region. [Abstract]: The COVID-19 pandemic began as a cluster of reported cases of acute respiratory illness in China on 31 December 2019 and went on to spread with exponential growth across the globe. By the time it...
32,528,732
NPJ Vaccines
Universal coronavirus vaccines: the time to start is now.
The continued explosive spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) despite aggressive public health measures has triggered an unprecedented international vaccine effort. However, correlates of protection, which can help guide intelligent vaccine design, are not known for SARS-CoV-2. Research...
influenza virus;sars-cov-2;vaccines;viral infection
Journal Article
Giurgea, Luca T;Han, Alison;Memoli, Matthew J
10.1038/s41541-020-0198-1
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Universal coronavirus vaccines: the time to start is now. [Abstract]: The continued explosive spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) despite aggressive public health measures has triggered an unprecedented international vaccine effort. However, correlates of protection, which ca...
32,350,543
Anaesthesist
[COVID-19 pandemic: structured expansion of ventilation capacities using home respirators].
Due to the current COVID-19 pandemic there is a need for a rapid increase in intensive care and ventilation capacities. Delivery times for additional intensive care respirators are currently not foreseeable. An option to increase ventilation capacities not only for COVID-19, but for all patients requiring mechanical ve...
emergency management;home respiration;intensive care unit;respiratory therapists;ressource management
Journal Article;Review
Summ, O;Schute, J;Byhahn, C;Kahle, T;Herrmann, M;Schulte, C;Bergold, M N;Gross, M
10.1007/s00101-020-00780-z
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [COVID-19 pandemic: structured expansion of ventilation capacities using home respirators]. [Abstract]: Due to the current COVID-19 pandemic there is a need for a rapid increase in intensive care and ventilation capacities. Delivery times for additional intensive care respirators are currently not foreseeable....
32,902,372
J Gen Virol
Predicting the recombination potential of severe acute respiratory syndrome coronavirus 2 and Middle East respiratory syndrome coronavirus.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) recently emerged to cause widespread infections in humans. SARS-CoV-2 infections have been reported in the Kingdom of Saudi Arabia, where Middle East respiratory syndrome coronavirus (MERS-CoV) causes seasonal outbreaks with a case fatality rate of ~37 %. Her...
mers-cov;sars-cov-2;coronavirus;emergence;predictions;recombination
Journal Article;Research Support, Non-U.S. Gov't
Banerjee, Arinjay;Doxey, Andrew C;Tremblay, Benjamin J-M;Mansfield, Michael J;Subudhi, Sonu;Hirota, Jeremy A;Miller, Matthew S;McArthur, Andrew G;Mubareka, Samira;Mossman, Karen
10.1099/jgv.0.001491
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Predicting the recombination potential of severe acute respiratory syndrome coronavirus 2 and Middle East respiratory syndrome coronavirus. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) recently emerged to cause widespread infections in humans. SARS-CoV-2 infections have been reporte...
32,810,370
Transbound Emerg Dis
Detection of SARS-CoV-2 in pets living with COVID-19 owners diagnosed during the COVID-19 lockdown in Spain: A case of an asymptomatic cat with SARS-CoV-2 in Europe.
Pets from COVID-19 owners were screened for SARS-CoV-2 (April-May 2020). From 23 pets, an asymptomatic cat showed positive RT-qPCRs results from oropharyngeal swab (negative rectal swab). Remaining pets were negative. This suggests that cats can contract the virus from their infected owners and may act as potential hos...
covid-19;sars-cov-2;spain;animals;cat;pets
Journal Article
Ruiz-Arrondo, Ignacio;Portillo, Aranzazu;Palomar, Ana M;Santibanez, Sonia;Santibanez, Paula;Cervera, Cristina;Oteo, Jose A
10.1111/tbed.13803
[ 0, 0, 0, 0, 1, 0, 0 ]
[Title]: Detection of SARS-CoV-2 in pets living with COVID-19 owners diagnosed during the COVID-19 lockdown in Spain: A case of an asymptomatic cat with SARS-CoV-2 in Europe. [Abstract]: Pets from COVID-19 owners were screened for SARS-CoV-2 (April-May 2020). From 23 pets, an asymptomatic cat showed positive RT-qPCRs r...
33,024,534
J Surg Case Rep
Case reports: mild COVID-19 infection and acute arterial thrombosis.
We present two cases of acute arterial thrombosis in patients who were confirmed to be SARS-CoV-2 positive. Neither of the patients had a background of underlying vascular morbidity. At the time of presentation, both patients exhibited only mild respiratory symptoms of COVID-19. After initial assessment and work-up, bo...
acute thrombosis;covid-19;acute ischemia;bowel ischemia;coronavirus
Case Reports
Osilli, Dixon;Pavlovica, Jelena;Mane, Rashi;Ibrahim, Mohammed;Bouhelal, Amina;Jacob, Sabu
10.1093/jscr/rjaa343
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Case reports: mild COVID-19 infection and acute arterial thrombosis. [Abstract]: We present two cases of acute arterial thrombosis in patients who were confirmed to be SARS-CoV-2 positive. Neither of the patients had a background of underlying vascular morbidity. At the time of presentation, both patients exhi...
32,824,985
Int J Mol Sci
4,4'-Diaminodiphenyl Sulfone (DDS) as an Inflammasome Competitor.
The aim of this study is to examine the use of an inflammasome competitor as a preventative agent. Coronaviruses have zoonotic potential due to the adaptability of their S protein to bind receptors of other species, most notably demonstrated by SARS-CoV. The binding of SARS-CoV-2 to TLR (Toll-like receptor) causes the ...
4,4'-diaminodiphenyl sulfone (dapsone);ad;alzheimer's disease;dds;ll;madds;mpo;nacht, lrr and pyd domains-containing protein 3;nlrp3;tlr;lepromatous leprosy (also known as hansen's disease);monoacetyldapsone;myeloperoxidase;toll-like receptor
Journal Article
Lee, Jong-Hoon;An, Ha Kyeu;Sohn, Mun-Gi;Kivela, Paul;Oh, Sangsuk
10.3390/ijms21175953
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: 4,4'-Diaminodiphenyl Sulfone (DDS) as an Inflammasome Competitor. [Abstract]: The aim of this study is to examine the use of an inflammasome competitor as a preventative agent. Coronaviruses have zoonotic potential due to the adaptability of their S protein to bind receptors of other species, most notably demo...
33,051,297
Proc Natl Acad Sci U S A
Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs.
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global crisis. There is no therapeutic treatment specific for COVID-19. It is highly desirable to identify potential antiviral agents against SARS-CoV-2 from existing drugs available for other diseases and thus rep...
sars-cov-2;drug repurposing;free energy perturbation;main protease;virtual screening
Journal Article;Research Support, Non-U.S. Gov't;Research Support, U.S. Gov't, Non-P.H.S.
Li, Zhe;Li, Xin;Huang, Yi-You;Wu, Yaoxing;Liu, Runduo;Zhou, Lingli;Lin, Yuxi;Wu, Deyan;Zhang, Lei;Liu, Hao;Xu, Ximing;Yu, Kunqian;Zhang, Yuxia;Cui, Jun;Zhan, Chang-Guo;Wang, Xin;Luo, Hai-Bin
10.1073/pnas.2010470117
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs. [Abstract]: The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global crisis. There is no therapeutic treatment specific...
32,575,958
Geospat Health
Spatiotemporal distribution and trend of COVID-19 in the Yangtze River Delta region of the People's Republic of China.
An outbreak of atypical pneumonia, now called COVID-19 and known to be caused by the novel coronavirus SARS-CoV-2, first detected in Wuhan, Hubei Province of the People's Republic of China in December 2019 and afterwards rapidly spread worldwide. Wuhan and the Yangtze River Delta (YRD) region implemented first-level pu...
Journal Article
Ye, Lei;Hu, Lingqian
10.4081/gh.2020.889
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Spatiotemporal distribution and trend of COVID-19 in the Yangtze River Delta region of the People's Republic of China. [Abstract]: An outbreak of atypical pneumonia, now called COVID-19 and known to be caused by the novel coronavirus SARS-CoV-2, first detected in Wuhan, Hubei Province of the People's Republic ...
32,546,188
Crit Care
The vascular endothelium: the cornerstone of organ dysfunction in severe SARS-CoV-2 infection.
In severe SARS-CoV-2 infections, emerging data including recent histopathological studies have emphasized the crucial role of endothelial cells (ECs) in vascular dysfunction, immunothrombosis, and inflammation.Histopathological studies have evidenced direct viral infection of ECs, endotheliitis with diffuse endothelial...
covid-19;cytokines;endothelial cells;endothelial dysfunction;sars-cov-2;thrombosis
Journal Article;Review
Pons, Stephanie;Fodil, Sofiane;Azoulay, Elie;Zafrani, Lara
10.1186/s13054-020-03062-7
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The vascular endothelium: the cornerstone of organ dysfunction in severe SARS-CoV-2 infection. [Abstract]: In severe SARS-CoV-2 infections, emerging data including recent histopathological studies have emphasized the crucial role of endothelial cells (ECs) in vascular dysfunction, immunothrombosis, and inflamm...