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32,255,491
Clin Sci (Lond)
ACE2 the Janus-faced protein - from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19.
Angiotensin converting enzyme 2 (ACE2) is the major enzyme responsible for conversion of Ang II into Ang-(1-7). It also acts as the receptor for severe acute respiratory syndrome (SARS)-coronavirus (CoV)-2, which causes Coronavirus Disease (COVID)-19. In recognition of the importance of ACE2 and to celebrate 20 years s...
ace2 receptor;angiotensin;covid-19;cardiovascular;coronavirus;hypertension
Editorial;Research Support, Non-U.S. Gov't
Touyz, Rhian M;Li, Hongliang;Delles, Christian
10.1042/CS20200363
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: ACE2 the Janus-faced protein - from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19. [Abstract]: Angiotensin converting enzyme 2 (ACE2) is the major enzyme responsible for conversion of Ang II into Ang-(1-7). It also acts as the receptor for severe acute respiratory synd...
32,474,966
Br J Soc Psychol
A social identity perspective on COVID-19: Health risk is affected by shared group membership.
In the face of a novel infectious disease, changing our collective behaviour is critical to saving lives. One determinant of risk perception and risk behaviour that is often overlooked is the degree to which we share psychological group membership with others. We outline, and summarize supporting evidence for, a theore...
behaviour change;group processes;health risk perception;risk taking;trust
Journal Article
Cruwys, Tegan;Stevens, Mark;Greenaway, Katharine H
10.1111/bjso.12391
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A social identity perspective on COVID-19: Health risk is affected by shared group membership. [Abstract]: In the face of a novel infectious disease, changing our collective behaviour is critical to saving lives. One determinant of risk perception and risk behaviour that is often overlooked is the degree to wh...
32,275,805
Emerg Med Australas
Clinical and ethical challenges for emergency departments during communicable disease outbreaks: Can lessons from Ebola Virus Disease be applied to the COVID-19 pandemic?
EDs fulfil a frontline function during public health emergencies (PHEs) and will play a pivotal role during the COVID-19 pandemic. This perspective article draws on qualitative data from a longitudinal, ethnographic study of an Australian tertiary ED to illustrate the clinical and ethical challenges faced by EDs during...
covid-19;ebola;public health
Journal Article
Markwell, Alexandra;Mitchell, Rob;Wright, April L;Brown, Anthony Ft
10.1111/1742-6723.13514
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Clinical and ethical challenges for emergency departments during communicable disease outbreaks: Can lessons from Ebola Virus Disease be applied to the COVID-19 pandemic? [Abstract]: EDs fulfil a frontline function during public health emergencies (PHEs) and will play a pivotal role during the COVID-19 pandemi...
32,911,141
Sci Total Environ
Quantitative microbial risk assessment of SARS-CoV-2 for workers in wastewater treatment plants.
Faecal-oral transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is yet to be validated, but it is a critical issue and additional research is needed to elucidate the risks of the novel coronavirus in sanitation systems. This is the first study that investigates the potential health risks of SAR...
emergency response plans;novel coronavirus;quantitative microbial risk assessment;sanitation;sewage;wastewater treatment plants
Journal Article
Zaneti, Rafael Newton;Girardi, Viviane;Spilki, Fernando Rosado;Mena, Kristina;Westphalen, Ana Paula Campos;da Costa Colares, Evandro Ricardo;Pozzebon, Allan Guedes;Etchepare, Ramiro Goncalves
10.1016/j.scitotenv.2020.142163
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Quantitative microbial risk assessment of SARS-CoV-2 for workers in wastewater treatment plants. [Abstract]: Faecal-oral transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is yet to be validated, but it is a critical issue and additional research is needed to elucidate the risks of th...
32,628,416
Curr Opin Otolaryngol Head Neck Surg
Considerations for the otolaryngologist in the era of COVID-19: a review of the literature.
PURPOSE OF REVIEW: The SARS-CoV-2 coronavirus pandemic, referred to as COVID-19, has spread throughout the globe since its first case in China in December 2019, leaving a significant number of people infected and clinically ill. The purpose of this review is to provide the current known clinical characteristics of and ...
Journal Article;Review
Miller, Lauren E;Shaye, David A;Lee, Linda N
10.1097/MOO.0000000000000632
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Considerations for the otolaryngologist in the era of COVID-19: a review of the literature. [Abstract]: PURPOSE OF REVIEW: The SARS-CoV-2 coronavirus pandemic, referred to as COVID-19, has spread throughout the globe since its first case in China in December 2019, leaving a significant number of people infecte...
32,591,663
Evid Based Dent
Provision of dental hospital services during the COVID-19 epidemic.
DATA SOURCES: Information about health services provision of public tertiary dental hospitals in China mainland was retrieved through a web search engine. DATA ANALYSIS: The status of non-emergency dental services, emergency dental services and online professional consultation was recorded and analysed. If telehealth w...
Journal Article;Comment
Yeung, C Albert
10.1038/s41432-020-0096-4
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Provision of dental hospital services during the COVID-19 epidemic. [Abstract]: DATA SOURCES: Information about health services provision of public tertiary dental hospitals in China mainland was retrieved through a web search engine. DATA ANALYSIS: The status of non-emergency dental services, emergency dental...
33,063,366
J Clin Lab Anal
Fecal occult blood and urinary cytology tests for rapid screening of inflammatory infection in the gastrointestinal and urological systems in patients with Coronavirus disease 2019.
BACKGROUND: Gastrointestinal infections (GI) and urological infections (UI) have not been fully addressed in COVID-19 patients. We aimed to evaluate the values of routine fecal occult blood (FOB) test and urinary cytology test (UCT) for screening of GI and UI in COVID-19 patients. METHODS: In this retrospective study, ...
covid-19;fecal occult blood test;gastrointestinal infection;urinary cytology test;urological infection
Journal Article
Du, Li;Cao, Xiaoling;Chen, Jing;Wei, Xiuqi;Zeng, Yi;Cheng, Chen;Lin, Yuqi;Tan, Wenbin;Wang, Hui
10.1002/jcla.23626
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Fecal occult blood and urinary cytology tests for rapid screening of inflammatory infection in the gastrointestinal and urological systems in patients with Coronavirus disease 2019. [Abstract]: BACKGROUND: Gastrointestinal infections (GI) and urological infections (UI) have not been fully addressed in COVID-19...
32,369,678
Andrology
SARS-CoV-2, testosterone and frailty in males (PROTEGGIMI): A multidimensional research project.
Preliminary published data depict a much greater prevalence of males with laboratory-confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) referred for intensive care unit admission and severe sequelae in several countries. In this context, males seem to not only be more susceptible to the infection co...
ace2;covid-19;sars-cov-2;andrology;endocrinology;male infertility;testosterone;urology
Journal Article
Salonia, Andrea;Corona, Giovanni;Giwercman, Aleksander;Maggi, Mario;Minhas, Suks;Nappi, Rossella E;Sofikitis, Nikolaos;Vignozzi, Linda
10.1111/andr.12811
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: SARS-CoV-2, testosterone and frailty in males (PROTEGGIMI): A multidimensional research project. [Abstract]: Preliminary published data depict a much greater prevalence of males with laboratory-confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) referred for intensive care unit admission and...
32,940,134
J Biomol Struct Dyn
A dynamic simulation study of FDA drug from zinc database against COVID-19 main protease receptor.
The sudden outbreak of COVID-19 has been responsible for several deaths across the globe. Due to its high contagious nature, it spreads from one human to another very quickly. Now it becomes a global public health threat with no approved treatments. In silico techniques can accelerate the drug development process. Our ...
fda drugs;sars-cov-2;main protease;molecular docking;molecular dynamic simulation;zinc database
Journal Article
Mathpal, Shalini;Joshi, Tushar;Sharma, Priyanka;Joshi, Tanuja;Pundir, Hemlata;Pande, Veena;Chandra, Subhash
10.1080/07391102.2020.1821785
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: A dynamic simulation study of FDA drug from zinc database against COVID-19 main protease receptor. [Abstract]: The sudden outbreak of COVID-19 has been responsible for several deaths across the globe. Due to its high contagious nature, it spreads from one human to another very quickly. Now it becomes a global ...
32,668,969
Am J Chin Med
Potential Targets for Treatment of Coronavirus Disease 2019 (COVID-19): A Review of Qing-Fei-Pai-Du-Tang and Its Major Herbs.
COVID-19 has been declared a pandemic by WHO on March 11, 2020. No specific treatment and vaccine with documented safety and efficacy for the disease have been established. Hence it is of utmost importance to identify more therapeutics such as Chinese medicine formulae to meet the urgent need. Qing Fei Pai Du Tang (QFP...
bupleurum chinense;cinnamomum cassia;coronavirus;ephedra sinica;glycyrrhiza uralensis;pogostemon cablin;qfpdt;scutellaria baicalensis;therapeutic targets
Historical Article;Journal Article;Review
Zhong, Linda Li Dan;Lam, Wai Ching;Yang, Wei;Chan, Kam Wa;Sze, Stephen Cho Wing;Miao, Jiangxia;Yung, Ken Kin Lam;Bian, Zhaoxiang;Wong, Vivian Taam
10.1142/S0192415X20500512
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Potential Targets for Treatment of Coronavirus Disease 2019 (COVID-19): A Review of Qing-Fei-Pai-Du-Tang and Its Major Herbs. [Abstract]: COVID-19 has been declared a pandemic by WHO on March 11, 2020. No specific treatment and vaccine with documented safety and efficacy for the disease have been established. ...
32,107,577
Eur J Nucl Med Mol Imaging
Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2.
BACKGROUND: The pneumonia caused by the 2019 novel coronavirus (SARS-CoV-2, also called 2019-nCoV) recently break out in Wuhan, China, and was named as COVID-19. With the spread of the disease, similar cases have also been confirmed in other regions of China. We aimed to report the imaging and clinical characteristics ...
2019 novel coronavirus pneumonia;covid-19;computed tomography;ground glass opacification;imaging features;infection;sars-cov-2
Journal Article
Xu, Xi;Yu, Chengcheng;Qu, Jing;Zhang, Lieguang;Jiang, Songfeng;Huang, Deyang;Chen, Bihua;Zhang, Zhiping;Guan, Wanhua;Ling, Zhoukun;Jiang, Rui;Hu, Tianli;Ding, Yan;Lin, Lin;Gan, Qingxin;Luo, Liangping;Tang, Xiaoping;Liu, Jinxin
10.1007/s00259-020-04735-9
[ 0, 1, 0, 1, 0, 0, 0 ]
[Title]: Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2. [Abstract]: BACKGROUND: The pneumonia caused by the 2019 novel coronavirus (SARS-CoV-2, also called 2019-nCoV) recently break out in Wuhan, China, and was named as COVID-19. With the spread of the disease, similar cases have also...
32,945,157
Rev Esp Quimioter
SARS-CoV-2 screening of asymptomatic women admitted for delivery must be performed with a combination of microbiological techniques: an observational study.
OBJECTIVE: The aim of this study is to assess the value of systematic screening in asymptomatic women admitted for spontaneous delivery with a combination of reverse transcription polymerase chain reaction (RT-PCR) and cycle threshold (Ct) and serum antibodies. METHODS: Since May 6 all women admitted for spontaneous de...
rt-pcr;sars-cov2;cycle threshold;delivery;screening;specific antibodies
Journal Article;Observational Study
Vinuela, M C;De Leon-Luis, J A;Alonso, R;Catalan, P;Lizarraga, S;Munoz, P;Bouza, E
10.37201/req/088.2020
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: SARS-CoV-2 screening of asymptomatic women admitted for delivery must be performed with a combination of microbiological techniques: an observational study. [Abstract]: OBJECTIVE: The aim of this study is to assess the value of systematic screening in asymptomatic women admitted for spontaneous delivery with a...
32,650,970
Rev Esp Patol
Autopsy findings from the first known death from Severe Acute Respiratory Syndrome SARS-CoV-2 in Spain.
The new coronavirus SARS-CoV-2, first identified in Wuhan, China in December, 2019, can cause Severe Acute Respiratory Syndrome (SARS) with massive alveolar damage and progressive respiratory failure. We present the relevant autopsy findings of the first patient known to have died from COVID19 pneumonia in Spain, carri...
autopsia;autopsy;covid-19;dano alveolar difuso;diffuse alveolar damage;sars-cov-2
Case Reports;Journal Article
Navarro Conde, Pedro;Alemany Monraval, Pilar;Medina Medina, Carmen;Jimenez Sanchez, Ana;Andres Teruel, Juan Carlos;Ferrando Marco, Jose;Puglia Santos, Victor;Mayordomo Aranda, Empar
10.1016/j.patol.2020.04.002
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Autopsy findings from the first known death from Severe Acute Respiratory Syndrome SARS-CoV-2 in Spain. [Abstract]: The new coronavirus SARS-CoV-2, first identified in Wuhan, China in December, 2019, can cause Severe Acute Respiratory Syndrome (SARS) with massive alveolar damage and progressive respiratory fai...
32,656,939
Rev Med Virol
Lessons from dermatology about inflammatory responses in Covid-19.
The SARS-Cov-2 is a single-stranded RNA virus composed of 16 non-structural proteins (NSP 1-16) with specific roles in the replication of coronaviruses. NSP3 has the property to block host innate immune response and to promote cytokine expression. NSP5 can inhibit interferon (IFN) signalling and NSP16 prevents MAD5 rec...
covid-19;sars-cov-2;innate immunity;lipoprotein a;livedoid vasculitis;skin
Journal Article;Review
Criado, Paulo Ricardo;Pagliari, Carla;Carneiro, Francisca Regina Oliveira;Quaresma, Juarez Antonio Simoes
10.1002/rmv.2130
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Lessons from dermatology about inflammatory responses in Covid-19. [Abstract]: The SARS-Cov-2 is a single-stranded RNA virus composed of 16 non-structural proteins (NSP 1-16) with specific roles in the replication of coronaviruses. NSP3 has the property to block host innate immune response and to promote cytok...
32,443,020
J Pediatr Gastroenterol Nutr
Corona Virus Disease 2019 and Paediatric Inflammatory Bowel Diseases: Global Experience and Provisional Guidance (March 2020) from the Paediatric IBD Porto Group of European Society of Paediatric Gastroenterology, Hepatology, and Nutrition.
INTRODUCTION: With the current coronavirus disease 2019 (COVID-19) pandemic, concerns have been raised about the risk to children with inflammatory bowel diseases (IBD). We aimed to collate global experience and provide provisional guidance for managing paediatric IBD (PIBD) in the era of COVID-19. METHODS: An electron...
Journal Article
Turner, Dan;Huang, Ying;Martin-de-Carpi, Javier;Aloi, Marina;Focht, Gili;Kang, Ben;Zhou, Ying;Sanchez, Cesar;Kappelman, Michael D;Uhlig, Holm H;Pujol-Muncunill, Gemma;Ledder, Oren;Lionetti, Paolo;Dias, Jorge Amil;Ruemmele, Frank M;Russell, Richard K
10.1097/MPG.0000000000002729
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Corona Virus Disease 2019 and Paediatric Inflammatory Bowel Diseases: Global Experience and Provisional Guidance (March 2020) from the Paediatric IBD Porto Group of European Society of Paediatric Gastroenterology, Hepatology, and Nutrition. [Abstract]: INTRODUCTION: With the current coronavirus disease 2019 (C...
32,343,013
Head Neck
Respiratory and pulmonary complications in head and neck cancer patients: Evidence-based review for the COVID-19 era.
BACKGROUND: Pulmonary complications and infections frequently affect patients with head and neck squamous cell carcinoma (HNSCC). Common characteristics can predispose these patients to the development of severe respiratory illness, which may be particularly relevant during the 2019 coronavirus disease (COVID-19) pande...
covid-19;adverse respiratory outcomes;head and neck squamous cell carcinoma (hnscc);pulmonary comorbidities;respiratory infections and complications
Journal Article;Review
Silverman, Dustin A;Lin, Chen;Tamaki, Akina;Puram, Sidharth V;Carrau, Ricardo L;Seim, Nolan B;Eskander, Antoine;Rocco, James W;Old, Matthew O;Kang, Stephen Y
10.1002/hed.26217
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Respiratory and pulmonary complications in head and neck cancer patients: Evidence-based review for the COVID-19 era. [Abstract]: BACKGROUND: Pulmonary complications and infections frequently affect patients with head and neck squamous cell carcinoma (HNSCC). Common characteristics can predispose these patient...
32,821,027
Telemed J E Health
Utilizing Telemedicine in a Novel Approach to COVID-19 Management and Patient Experience in the Emergency Department.
Background: The COVID-19 crisis has highlighted telemedicine as a care delivery tool uniquely suited for a disaster pandemic. Introduction: With support from emergency department (ED) leadership, our institution rapidly deployed telemedicine in a novel approach to large-scale ED infectious disease management at NewYork...
emergency medicine/teletrauma;pandemic;technology;telemedicine
Journal Article;Research Support, Non-U.S. Gov't
Bains, Jaskaran;Greenwald, Peter W;Mulcare, Mary R;Leyden, David;Kim, Joshua;Shemesh, Amos J;Bodnar, David;Farmer, Brenna;Steel, Peter;Tanouye, Robert;Kim, Ji Won;Lame, Maria;Sharma, Rahul
10.1089/tmj.2020.0162
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Utilizing Telemedicine in a Novel Approach to COVID-19 Management and Patient Experience in the Emergency Department. [Abstract]: Background: The COVID-19 crisis has highlighted telemedicine as a care delivery tool uniquely suited for a disaster pandemic. Introduction: With support from emergency department (E...
32,365,287
Emerg Med Pract
Emergency department COVID management policies: one institution's experience and lessons learned.
Coronavirus disease (COVID-19), caused by the SARS-CoV-2 virus, originated in Wuhan, Hubei Province, China in late 2019 and grew rapidly into a pandemic. As of the writing of this monograph, there are over 2 million confirmed cases worldwide and 147,000 deaths. New York City, with over 120,000 COVID-19-positive patient...
Journal Article
Leibner, Evan S;Stokes, Sonya;Ahmad, Danish;Legome, Eric
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Emergency department COVID management policies: one institution's experience and lessons learned. [Abstract]: Coronavirus disease (COVID-19), caused by the SARS-CoV-2 virus, originated in Wuhan, Hubei Province, China in late 2019 and grew rapidly into a pandemic. As of the writing of this monograph, there are ...
32,387,968
J Clin Virol
Clinical evaluation of an immunochromatographic IgM/IgG antibody assay and chest computed tomography for the diagnosis of COVID-19.
BACKGROUND: We evaluated the clinical performance of an immunochromatographic (IC) IgM/IgG antibody assay for severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) and chest computed tomography (CT) for the diagnosis of Coronavirus disease 2019 (COVID-19). METHODS: We examined 139 serum specimens collected from 1...
covid-19;chest ct scan;immunochromatographic assay;sars-cov-2
Comparative Study;Evaluation Study;Journal Article
Imai, Kazuo;Tabata, Sakiko;Ikeda, Mayu;Noguchi, Sakiko;Kitagawa, Yutaro;Matuoka, Masaru;Miyoshi, Kazuyasu;Tarumoto, Norihito;Sakai, Jun;Ito, Toshimitsu;Maesaki, Shigefumi;Tamura, Kaku;Maeda, Takuya
10.1016/j.jcv.2020.104393
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical evaluation of an immunochromatographic IgM/IgG antibody assay and chest computed tomography for the diagnosis of COVID-19. [Abstract]: BACKGROUND: We evaluated the clinical performance of an immunochromatographic (IC) IgM/IgG antibody assay for severe acute respiratory syndrome coronavirus 2 (SARS-CoV...
32,334,392
Diabetes Metab Syndr
Enhancing immunity in viral infections, with special emphasis on COVID-19: A review.
BACKGROUND AND AIMS: Balanced nutrition which can help in maintaining immunity is essential for prevention and management of viral infections. While data regarding nutrition in coronavirus infection (COVID-19) are not available, in this review, we aimed to evaluate evidence from previous clinical trials that studied nu...
Journal Article;Systematic Review
Jayawardena, Ranil;Sooriyaarachchi, Piumika;Chourdakis, Michail;Jeewandara, Chandima;Ranasinghe, Priyanga
10.1016/j.dsx.2020.04.015
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Enhancing immunity in viral infections, with special emphasis on COVID-19: A review. [Abstract]: BACKGROUND AND AIMS: Balanced nutrition which can help in maintaining immunity is essential for prevention and management of viral infections. While data regarding nutrition in coronavirus infection (COVID-19) are ...
32,903,453
Front Med (Lausanne)
A Dental Response to the COVID-19 Pandemic-Safer Aerosol-Free Emergent (SAFER) Dentistry.
Dental services are significantly impacted by the COVID-19 pandemic. Almost all dental procedures carry a high infection risk for providers and patients due to the spread of aerosols. As a consequence, public health agencies and professional associations have issued guidelines for enhanced infection control and persona...
covid-19;airborne transmission of diseases;dental care;emergency dental service;infection control;infectious dental aerosols;pandemic preparedness and response
Journal Article
Benzian, Habib;Niederman, Richard
10.3389/fmed.2020.00520
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A Dental Response to the COVID-19 Pandemic-Safer Aerosol-Free Emergent (SAFER) Dentistry. [Abstract]: Dental services are significantly impacted by the COVID-19 pandemic. Almost all dental procedures carry a high infection risk for providers and patients due to the spread of aerosols. As a consequence, public ...
32,902,338
Hum Factors
Interpersonal Distance in the SARS-CoV-2 Crisis.
BACKGROUND: Mandatory rules for social distancing to curb the SARS-CoV-2 pandemic require individuals to maintain a critical interpersonal distance above 1.5 m. However, this contradicts our natural preference, which is closer to 1 m for non-intimate encounters, for example, when asking a stranger for directions. OBJEC...
sars-cov-2;discomfort;interpersonal distance;proxemics
Journal Article;Research Support, Non-U.S. Gov't
Welsch, Robin;Hecht, Heiko;Chuang, Lewis;von Castell, Christoph
10.1177/0018720820956858
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Interpersonal Distance in the SARS-CoV-2 Crisis. [Abstract]: BACKGROUND: Mandatory rules for social distancing to curb the SARS-CoV-2 pandemic require individuals to maintain a critical interpersonal distance above 1.5 m. However, this contradicts our natural preference, which is closer to 1 m for non-intimate...
32,558,193
Dermatol Ther
Patients with specific skin disorders who are affected by COVID-19: What do experiences say about management strategies? A systematic review.
In patients with specific dermatologic disorders who are affected by new corona virus, we know little about disease course (underlying disease and new onset infection), and the most proper management strategies include both issues that are what this systematic review targets. Databases of PubMed, Scopus, Google Scholar...
covid-19;biologic;concomitant;concurrent;corona virus;cutaneous;immunobullous;immunomodulator;immunosuppressive;manifestation;novel human coronavirus (sars-cov-2);pemphigoid;pemphigus;psoriasis;psoriatic arthritis;simultaneous;skin;specific skin disease;systematic review;systemic drug
Journal Article;Review
Nobari, Niloufar Najar;Goodarzi, Azadeh
10.1111/dth.13867
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Patients with specific skin disorders who are affected by COVID-19: What do experiences say about management strategies? A systematic review. [Abstract]: In patients with specific dermatologic disorders who are affected by new corona virus, we know little about disease course (underlying disease and new onset ...
32,371,472
mSystems
SARS-CoV-2 and ORF3a: Nonsynonymous Mutations, Functional Domains, and Viral Pathogenesis.
The effect of the rapid accumulation of nonsynonymous mutations on the pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is not yet known. The 3a protein is unique to SARS-CoV and is essential for disease pathogenesis. Our study aimed at determining the nonsynonymous mutations in the 3a prote...
3a protein;covid-19;orf3a;sars-cov-2;nonsynonymous mutations
Journal Article
Issa, Elio;Merhi, Georgi;Panossian, Balig;Salloum, Tamara;Tokajian, Sima
10.1128/mSystems.00266-20
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: SARS-CoV-2 and ORF3a: Nonsynonymous Mutations, Functional Domains, and Viral Pathogenesis. [Abstract]: The effect of the rapid accumulation of nonsynonymous mutations on the pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is not yet known. The 3a protein is unique to SARS-CoV and i...
32,519,760
J Med Virol
Diagnosis of COVID-19 pneumonia despite missing detection of viral nucleic acid and initially inconspicuous radiologic findings.
The diagnosis of coronavirus disease 2019 (COVID-19) is mainly based on a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR) result. PCR samples are obtained from upper or lower respiratory tract specimens. However, the sensitivity of PCR is known to have some limitati...
covid-19;sars-cov-2;pneumonia
Case Reports;Journal Article
Schiller, Martin;Wydra, Stephan;Kerl, Hans Ulrich;Kick, Wolfgang
10.1002/jmv.26153
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Diagnosis of COVID-19 pneumonia despite missing detection of viral nucleic acid and initially inconspicuous radiologic findings. [Abstract]: The diagnosis of coronavirus disease 2019 (COVID-19) is mainly based on a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction ...
32,677,778
Can J Surg
Surgical training in the midst of a pandemic: a distributed general surgery residency program's response to COVID-19.
Summary: The coronavirus disease 2019 (COVID-19) pandemic has had a substantial impact on surgical training. We describe some of the challenges brought on by the pandemic and our program's province-wide response to them. We focus specifically on residents' provision of service, education and wellness.
Journal Article
Hintz, Graeme C;Duncan, Katrina C;Mackay, Emily M;Scott, Tracy M;Karimuddin, Ahmer A
10.1503/cjs.008420
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Surgical training in the midst of a pandemic: a distributed general surgery residency program's response to COVID-19. [Abstract]: Summary: The coronavirus disease 2019 (COVID-19) pandemic has had a substantial impact on surgical training. We describe some of the challenges brought on by the pandemic and our pr...
32,834,583
Chaos Solitons Fractals
Association between weather data and COVID-19 pandemic predicting mortality rate: Machine learning approaches.
Nowadays, a significant number of infectious diseases such as human coronavirus disease (COVID-19) are threatening the world by spreading at an alarming rate. Some of the literatures pointed out that the pandemic is exhibiting seasonal patterns in its spread, incidence and nature of the distribution. In connection to t...
covid-19;humidity;machine learning;ols;prediction;temperature
Journal Article
Malki, Zohair;Atlam, El-Sayed;Hassanien, Aboul Ella;Dagnew, Guesh;Elhosseini, Mostafa A;Gad, Ibrahim
10.1016/j.chaos.2020.110137
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Association between weather data and COVID-19 pandemic predicting mortality rate: Machine learning approaches. [Abstract]: Nowadays, a significant number of infectious diseases such as human coronavirus disease (COVID-19) are threatening the world by spreading at an alarming rate. Some of the literatures point...
32,983,174
Front Immunol
Re-analysis of Single Cell Transcriptome Reveals That the NR3C1-CXCL8-Neutrophil Axis Determines the Severity of COVID-19.
SARS-CoV-2 infection has recently been declared a pandemic. Some patients showing severe symptoms exhibit drastic inflammation and airway damage. In this study, we re-analyzed published scRNA-seq data of COVID-19 patient bronchoalveolar lavage fluid to further classify and compare immunological features according to th...
bal;covid-19;cxcl8;sars-cov-2;glucocorticoid;neutrophil;scrna-seq
Journal Article;Research Support, Non-U.S. Gov't
Park, Jang Hyun;Lee, Heung Kyu
10.3389/fimmu.2020.02145
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Re-analysis of Single Cell Transcriptome Reveals That the NR3C1-CXCL8-Neutrophil Axis Determines the Severity of COVID-19. [Abstract]: SARS-CoV-2 infection has recently been declared a pandemic. Some patients showing severe symptoms exhibit drastic inflammation and airway damage. In this study, we re-analyzed ...
32,770,169
Nat Med
Using a real-world network to model localized COVID-19 control strategies.
Case isolation and contact tracing can contribute to the control of COVID-19 outbreaks(1,2). However, it remains unclear how real-world social networks could influence the effectiveness and efficiency of such approaches. To address this issue, we simulated control strategies for SARS-CoV-2 transmission in a real-world ...
Journal Article;Research Support, Non-U.S. Gov't
Firth, Josh A;Hellewell, Joel;Klepac, Petra;Kissler, Stephen;Kucharski, Adam J;Spurgin, Lewis G
10.1038/s41591-020-1036-8
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Using a real-world network to model localized COVID-19 control strategies. [Abstract]: Case isolation and contact tracing can contribute to the control of COVID-19 outbreaks(1,2). However, it remains unclear how real-world social networks could influence the effectiveness and efficiency of such approaches. To ...
32,404,050
BMC Med Res Methodol
Social media as a recruitment platform for a nationwide online survey of COVID-19 knowledge, beliefs, and practices in the United States: methodology and feasibility analysis.
BACKGROUND: The COVID-19 pandemic has evolved into one of the most impactful health crises in modern history, compelling researchers to explore innovative ways to efficiently collect public health data in a timely manner. Social media platforms have been explored as a research recruitment tool in other settings; howeve...
beliefs;covid-19;coronavirus;facebook;infectious disease;knowledge;methodology;practices;social media;surveillance
Journal Article
Ali, Shahmir H;Foreman, Joshua;Capasso, Ariadna;Jones, Abbey M;Tozan, Yesim;DiClemente, Ralph J
10.1186/s12874-020-01011-0
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Social media as a recruitment platform for a nationwide online survey of COVID-19 knowledge, beliefs, and practices in the United States: methodology and feasibility analysis. [Abstract]: BACKGROUND: The COVID-19 pandemic has evolved into one of the most impactful health crises in modern history, compelling re...
32,529,545
Nat Prod Bioprospect
Natural Products as Potential Leads Against Coronaviruses: Could They be Encouraging Structural Models Against SARS-CoV-2?
New coronavirus referred to SARS-CoV-2 has caused a worldwide pandemic (COVID-19) declared by WHO. Coronavirus disease 2019 (COVID-19) is an infectious disease with severe acute respiratory syndrome caused by coronavirus-2 (SARS-CoV-2). SARS-CoV-2 is akin to SARS-CoV, which was the causative agent of severe acute respi...
antiviral;coronavirus;medicinal plants;natural products;sars-cov
Journal Article;Review
Orhan, Ilkay Erdogan;Senol Deniz, F Sezer
10.1007/s13659-020-00250-4
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Natural Products as Potential Leads Against Coronaviruses: Could They be Encouraging Structural Models Against SARS-CoV-2? [Abstract]: New coronavirus referred to SARS-CoV-2 has caused a worldwide pandemic (COVID-19) declared by WHO. Coronavirus disease 2019 (COVID-19) is an infectious disease with severe acut...
32,830,564
Health Promot Pract
Mobilizing a Community-Academic Partnership to Provide DIY Handwashing Stations to Skid Row Residents During COVID-19.
The coronavirus (COVID-19) pandemic is having a devastating impact on global health. In the United States and abroad, there is concern for how the novel coronavirus will affect vulnerable populations, including people experiencing homelessness. Individuals who lack stable housing are more likely to have preexisting hea...
academic-community partnerships;handwashing;hygiene;participatory action research;prevention
Journal Article
DiGuiseppi, Graham;Corcoran, Callahan;Cunningham, Todd;Nguyen, Hoan;Noel, Monique;White, Pete;Bar, Francois
10.1177/1524839920953092
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Mobilizing a Community-Academic Partnership to Provide DIY Handwashing Stations to Skid Row Residents During COVID-19. [Abstract]: The coronavirus (COVID-19) pandemic is having a devastating impact on global health. In the United States and abroad, there is concern for how the novel coronavirus will affect vul...
32,993,736
Crit Care
COVID-19: instruments for the allocation of mechanical ventilators-a narrative review.
After the World Health Organization declared COVID-19 to be a pandemic, the elaboration of comprehensive and preventive public policies became important in order to stop the spread of the disease. However, insufficient or ineffective measures may have placed health professionals and services in the position of having t...
decision making;ethics;health care rationing;pandemics
Journal Article;Review
Dos Santos, Marcelo Jose;Martins, Maristela Santini;Santana, Fabiana Lopes Pereira;Furtado, Maria Carolina Silvano Pacheco Correa;Miname, Fabiana Cristina Bazana Remedio;Pimentel, Rafael Rodrigo da Silva;Brito, Agata Nunes;Schneider, Patrick;Dos Santos, Edson Silva;da Silva, Luciane Hupalo
10.1186/s13054-020-03298-3
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19: instruments for the allocation of mechanical ventilators-a narrative review. [Abstract]: After the World Health Organization declared COVID-19 to be a pandemic, the elaboration of comprehensive and preventive public policies became important in order to stop the spread of the disease. However, insuff...
33,045,016
PLoS One
Spatial association patterns between post-acute care services and acute care facilities in the United States.
BACKGROUND: There is increasing demand for post-acute care services, which is amplified by the COVID-19 pandemic. AIMS: We studied the pattern of spatial association between post-acute care services and acute care facilities and evaluated how geographic variability could influence their use. METHODS: We compiled data o...
Journal Article
Ziakas, Panayiotis D;Mylonakis, Eleftherios
10.1371/journal.pone.0240624
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Spatial association patterns between post-acute care services and acute care facilities in the United States. [Abstract]: BACKGROUND: There is increasing demand for post-acute care services, which is amplified by the COVID-19 pandemic. AIMS: We studied the pattern of spatial association between post-acute care...
32,448,757
Curr Probl Cardiol
The Iranian Society of Echocardiography (ISE) Statement on Performing Echocardiography During the COVID-19 Pandemic.
Corona virus disease 2019(COVID-19) pandemic has caused a significant burden on the global health system. Considerable cardiovascular involvement has been reported among COVID-19 patients with higher ICU admission and mortality rates among patients with cardiovascular comorbidities. Consequently, diagnostic cardiovascu...
Journal Article;Practice Guideline;Review
Sattarzadeh Badkoubeh, Roya;Almassi, Nooshin;Moshkani Farahani, Maryam;Movassaghi, Naser;Khosravi, Arezoo;Mirdamadi, Ahmad;Kamali, Monireh;Manshouri, Shirin;Toufan Tabrizi, Mehrnoush;Farrashi, Melody;Samiei, Niloufar
10.1016/j.cpcardiol.2020.100620
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Iranian Society of Echocardiography (ISE) Statement on Performing Echocardiography During the COVID-19 Pandemic. [Abstract]: Corona virus disease 2019(COVID-19) pandemic has caused a significant burden on the global health system. Considerable cardiovascular involvement has been reported among COVID-19 pat...
32,994,364
Science
Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity.
Understanding humoral responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical for improving diagnostics, therapeutics, and vaccines. Deep serological profiling of 232 coronavirus disease 2019 (COVID-19) patients and 190 pre-COVID-19 era controls using VirScan revealed more than 800 epitope...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't;Research Support, U.S. Gov't, Non-P.H.S.
Shrock, Ellen;Fujimura, Eric;Kula, Tomasz;Timms, Richard T;Lee, I-Hsiu;Leng, Yumei;Robinson, Matthew L;Sie, Brandon M;Li, Mamie Z;Chen, Yuezhou;Logue, Jennifer;Zuiani, Adam;McCulloch, Denise;Lelis, Felipe J N;Henson, Stephanie;Monaco, Daniel R;Travers, Meghan;Habibi, Shaghayegh;Clarke, William A;Caturegli, Patrizio;Lae...
10.1126/science.abd4250
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity. [Abstract]: Understanding humoral responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical for improving diagnostics, therapeutics, and vaccines. Deep serological profiling of 232 coro...
32,193,638
Eur Radiol
Chest CT manifestations of new coronavirus disease 2019 (COVID-19): a pictorial review.
Coronavirus disease 2019 (COVID-19) outbreak, first reported in Wuhan, China, has rapidly swept around the world just within a month, causing global public health emergency. In diagnosis, chest computed tomography (CT) manifestations can supplement parts of limitations of real-time reverse transcription polymerase chai...
coronavirus infections;pneumonia;tomography, x-ray computed
Journal Article;Review
Ye, Zheng;Zhang, Yun;Wang, Yi;Huang, Zixiang;Song, Bin
10.1007/s00330-020-06801-0
[ 0, 1, 0, 1, 0, 0, 0 ]
[Title]: Chest CT manifestations of new coronavirus disease 2019 (COVID-19): a pictorial review. [Abstract]: Coronavirus disease 2019 (COVID-19) outbreak, first reported in Wuhan, China, has rapidly swept around the world just within a month, causing global public health emergency. In diagnosis, chest computed tomograp...
32,841,283
PLoS One
Simulating the progression of the COVID-19 disease in Cameroon using SIR models.
This paper analyses the evolution of COVID-19 in Cameroon over the period March 6-April 2020 using SIR models. Specifically, we 1) evaluate the basic reproduction number of the virus, 2) determine the peak of the infection and the spread-out period of the disease, and 3) simulate the interventions of public health auth...
Journal Article
Nguemdjo, Ulrich;Meno, Freeman;Dongfack, Audric;Ventelou, Bruno
10.1371/journal.pone.0237832
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Simulating the progression of the COVID-19 disease in Cameroon using SIR models. [Abstract]: This paper analyses the evolution of COVID-19 in Cameroon over the period March 6-April 2020 using SIR models. Specifically, we 1) evaluate the basic reproduction number of the virus, 2) determine the peak of the infec...
32,853,599
J Infect
COVID-19 patients display distinct SARS-CoV-2 specific T-cell responses according to disease severity.
Adaptive Immune responses generated by SARS-CoV-2 virus in convalescent patients according to disease severity remain poorly characterized. To this end, we designed a prospective study (NCT04365322) that included 60 COVID-19 convalescent patients (1-month post infection) in two cohorts respectively entitled mild illnes...
adaptive immunity;covid-19;coronavirus;interferon;sars-cov-2;t-cells
Letter;Comment
Kroemer, Marie;Spehner, Laurie;Vettoretti, Lucie;Bouard, Adeline;Eberst, Guillaume;Pili Floury, Sebastien;Capellier, Gilles;Lepiller, Quentin;Orillard, Emeline;Mansi, Laura;Clairet, Anne-Laure;Westeel, Virginie;Limat, Samuel;Dubois, Maxime;Malinowski, Lea;Bohard, Louis;Borg, Christophe;Chirouze, Catherine;Bouiller, Kev...
10.1016/j.jinf.2020.08.036
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: COVID-19 patients display distinct SARS-CoV-2 specific T-cell responses according to disease severity. [Abstract]: Adaptive Immune responses generated by SARS-CoV-2 virus in convalescent patients according to disease severity remain poorly characterized. To this end, we designed a prospective study (NCT0436532...
32,523,928
Eur J Case Rep Intern Med
D-dimer and C-reactive Protein Blood Levels Over Time Used to Predict Pulmonary Embolism in Two COVID-19 Patients.
The diagnosis of pulmonary embolism is challenging in symptomatic COVID-19 patients since shortness of breath, chest pain, tachycardia, tachypnoea, fever, oxygen desaturation and high D-dimer blood levels might be features of both diseases. We present two COVID-19 patients in whom pulmonary embolism was suspected (and ...
c-reactive protein;covid-19;d-dimer;pulmonary embolism
Journal Article
Becher, Yael;Goldman, Leonid;Schacham, Nadav;Gringauz, Irina;Justo, Dan
10.12890/2020_001725
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: D-dimer and C-reactive Protein Blood Levels Over Time Used to Predict Pulmonary Embolism in Two COVID-19 Patients. [Abstract]: The diagnosis of pulmonary embolism is challenging in symptomatic COVID-19 patients since shortness of breath, chest pain, tachycardia, tachypnoea, fever, oxygen desaturation and high ...
32,354,022
Viruses
ACE2: The key Molecule for Understanding the Pathophysiology of Severe and Critical Conditions of COVID-19: Demon or Angel?
Recently, the SARS-CoV-2 induced disease COVID-19 has spread all over the world. Nearly 20% of the patients have severe or critical conditions. SARS-CoV-2 exploits ACE2 for host cell entry. ACE2 plays an essential role in the renin-angiotensin-aldosterone system (RAAS), which regulates blood pressure and fluid balance....
ace2;adam17;ang-(1-7);b0at1;covid-19;raas;sars-cov-2;tmprss2
Journal Article
Xiao, Li;Sakagami, Hiroshi;Miwa, Nobuhiko
10.3390/v12050491
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: ACE2: The key Molecule for Understanding the Pathophysiology of Severe and Critical Conditions of COVID-19: Demon or Angel? [Abstract]: Recently, the SARS-CoV-2 induced disease COVID-19 has spread all over the world. Nearly 20% of the patients have severe or critical conditions. SARS-CoV-2 exploits ACE2 for ho...
32,395,965
Ned Tijdschr Geneeskd
[Chest pain and dyspnea during the recovery period of COVID-19 pneumonia].
A 31-year-old non-smoking male patient admitted with and intubated for COVID-19 pneumonia experienced acute chest pain and dyspnea during his recovery period. He was diagnosed with a pneumothorax based on major bullae formation due to COVID-19. The bullae were not visible after extubation and developed rapidly within a...
Case Reports;Journal Article
Bloemen, Hannah;Hagmolen Of Ten Have, Wanda;Clappers-Gielen, Giny A L
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: [Chest pain and dyspnea during the recovery period of COVID-19 pneumonia]. [Abstract]: A 31-year-old non-smoking male patient admitted with and intubated for COVID-19 pneumonia experienced acute chest pain and dyspnea during his recovery period. He was diagnosed with a pneumothorax based on major bullae format...
32,497,459
Hosp Pract (1995)
Acidified sodium chlorite solution: A potential prophylaxis to mitigate impact of multiple exposures to COVID-19 in frontline health-care providers.
Limited availability of personal protective equipment is endangering first-line health-care providers treating patients with presumed or confirmed COVID-19 infections. This editorial has multiple objectives in regard to this reality: First, to raise awareness of the need for safe and effective prophylaxis to protect he...
covid-19 prophylaxis;acidified sodium chlorite solution;chlorine dioxide solution;chlorous acid solution;personal protective equipment (ppe)
Editorial
Karnik-Henry, Meghana S
10.1080/21548331.2020.1778908
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Acidified sodium chlorite solution: A potential prophylaxis to mitigate impact of multiple exposures to COVID-19 in frontline health-care providers. [Abstract]: Limited availability of personal protective equipment is endangering first-line health-care providers treating patients with presumed or confirmed COV...
32,687,345
J Chem Inf Model
Structure-Based Virtual Screening to Discover Potential Lead Molecules for the SARS-CoV-2 Main Protease.
The COVID-19 disease is caused by a new strain of the coronavirus family (SARS-CoV-2), and it has affected at present millions of people all over the world. The indispensable role of the main protease (M(pro)) in viral replication and gene expression makes this enzyme an attractive drug target. Therefore, inhibition of...
Journal Article
Gahlawat, Anuj;Kumar, Navneet;Kumar, Rajender;Sandhu, Hardeep;Singh, Inder Pal;Singh, Saranjit;Sjostedt, Anders;Garg, Prabha
10.1021/acs.jcim.0c00546
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Structure-Based Virtual Screening to Discover Potential Lead Molecules for the SARS-CoV-2 Main Protease. [Abstract]: The COVID-19 disease is caused by a new strain of the coronavirus family (SARS-CoV-2), and it has affected at present millions of people all over the world. The indispensable role of the main pr...
32,304,371
Salud Publica Mex
[Public health literacy in the face of the Covid-19 pandemic emergency].
Health literacy is the process of obtaining knowledge, motivation and individual competencies to understand and access information, express opinions and make decisions with respect to health promotion and maintenance. This applies in different contexts, environments, and throughout life. This conceptual perspective is ...
covid-19;mexico;sars-cov-2;health literacy;surveillance
Journal Article
Lazcano-Ponce, Eduardo;Alpuche-Aranda, Celia
10.21149/11408
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Public health literacy in the face of the Covid-19 pandemic emergency]. [Abstract]: Health literacy is the process of obtaining knowledge, motivation and individual competencies to understand and access information, express opinions and make decisions with respect to health promotion and maintenance. This app...
32,738,193
Cell Host Microbe
A Replication-Competent Vesicular Stomatitis Virus for Studies of SARS-CoV-2 Spike-Mediated Cell Entry and Its Inhibition.
There is an urgent need for vaccines and therapeutics to prevent and treat COVID-19. Rapid SARS-CoV-2 countermeasure development is contingent on the availability of robust, scalable, and readily deployable surrogate viral assays to screen antiviral humoral responses, define correlates of immune protection, and down-se...
ace2;covid-19;sars-cov-2;vsv;antiviral drugs;convalescent plasma;neutralization assay;neutralizing antibody;serology;surrogate
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Dieterle, M Eugenia;Haslwanter, Denise;Bortz, Robert H 3rd;Wirchnianski, Ariel S;Lasso, Gorka;Vergnolle, Olivia;Abbasi, Shawn A;Fels, J Maximilian;Laudermilch, Ethan;Florez, Catalina;Mengotto, Amanda;Kimmel, Duncan;Malonis, Ryan J;Georgiev, George;Quiroz, Jose;Barnhill, Jason;Pirofski, Liise-Anne;Daily, Johanna P;Dye, ...
10.1016/j.chom.2020.06.020
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: A Replication-Competent Vesicular Stomatitis Virus for Studies of SARS-CoV-2 Spike-Mediated Cell Entry and Its Inhibition. [Abstract]: There is an urgent need for vaccines and therapeutics to prevent and treat COVID-19. Rapid SARS-CoV-2 countermeasure development is contingent on the availability of robust, sc...
32,678,695
Hum Vaccin Immunother
Neutralizing and cross-reacting antibodies: implications for immunotherapy and SARS-CoV-2 vaccine development.
The novel coronavirus SARS-CoV-2 emerged in China in 2019 and quickly spread globally, causing a pandemic. There is an urgent need to develop vaccines against the virus, and both convalescent plasma and immune globulin are currently in clinical trials for treatment of patients with COVID-19. It is unclear whether antib...
covid-19;immunotherapy;pregnancy;vaccine
Journal Article;Research Support, Non-U.S. Gov't;Review
Cohen, Samuel A;Kellogg, Caitlyn;Equils, Ozlem
10.1080/21645515.2020.1787074
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Neutralizing and cross-reacting antibodies: implications for immunotherapy and SARS-CoV-2 vaccine development. [Abstract]: The novel coronavirus SARS-CoV-2 emerged in China in 2019 and quickly spread globally, causing a pandemic. There is an urgent need to develop vaccines against the virus, and both convalesc...
32,934,084
mBio
A Potent Postentry Restriction to Primate Lentiviruses in a Yinpterochiropteran Bat.
Bats are primary reservoirs for multiple lethal human viruses, such as Ebola, Nipah, Hendra, rabies, severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome-related coronavirus (MERS-CoV), and, most recently, SARS-CoV-2. The innate immune systems of these immensely abundant, anciently...
hiv-1;mx2;megachiroptera;pteropus alecto;yinpterchiroptera;bats;cyclophilin a;lentivirus;restriction factor;restriction factors;retrovirus
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Morrison, James H;Miller, Caitlin;Bankers, Laura;Crameri, Gary;Wang, Lin-Fa;Poeschla, Eric M
10.1128/mBio.01854-20
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: A Potent Postentry Restriction to Primate Lentiviruses in a Yinpterochiropteran Bat. [Abstract]: Bats are primary reservoirs for multiple lethal human viruses, such as Ebola, Nipah, Hendra, rabies, severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome-related coronavirus (M...
32,278,758
Travel Med Infect Dis
A cross-sectional comparison of epidemiological and clinical features of patients with coronavirus disease (COVID-19) in Wuhan and outside Wuhan, China.
BACKGROUND: Coronavirus disease 2019 (COVID-19) has spread outside the initial epicenter of Wuhan. We compared cases in Guangzhou and Wuhan to illustrate potential changes in pathogenicity and epidemiological characteristics as the epidemic has progressed. METHODS: We studied 20 patients admitted to the Third Affiliate...
clinical features;coronavirus disease 2019;epidemiology;severe acute respiratory syndrome-related coronavirus 2;transmission;virulence
Journal Article
Lei, Ziying;Cao, Huijuan;Jie, Yusheng;Huang, Zhanlian;Guo, Xiaoyan;Chen, Junfeng;Peng, Liang;Cao, Hong;Dai, Xiaoling;Liu, Jing;Li, Xuejun;Zhu, Jianyun;Xu, Wenxiong;Chen, Dabiao;Gao, Zhiliang;He, Jian-Rong;Lin, Bing-Liang
10.1016/j.tmaid.2020.101664
[ 0, 1, 0, 0, 1, 0, 0 ]
[Title]: A cross-sectional comparison of epidemiological and clinical features of patients with coronavirus disease (COVID-19) in Wuhan and outside Wuhan, China. [Abstract]: BACKGROUND: Coronavirus disease 2019 (COVID-19) has spread outside the initial epicenter of Wuhan. We compared cases in Guangzhou and Wuhan to ill...
32,773,471
AIDS
Clinical characteristics, risk factors, and incidence of symptomatic coronavirus disease 2019 in a large cohort of adults living with HIV: a single-center, prospective observational study.
BACKGROUND: It is unclear how characteristics, risk factors, and incidence of coronavirus disease 2019 (COVID-19) in people living with HIV (PLWH) differ from the general population. METHODS: Prospective observational single-center cohort study of adult PLWH reporting symptoms of COVID-19. We assessed clinical characte...
Journal Article;Observational Study
Inciarte, Alexy;Gonzalez-Cordon, Ana;Rojas, Jhon;Torres, Berta;de Lazzari, Elisa;de la Mora, Lorena;Martinez-Rebollar, Maria;Laguno, Montserrat;Callau, Pilar;Gonzalez-Navarro, Azucena;Leal, Lorna;Garcia, Felipe;Mallolas, Josep;Mosquera, Mar;Marcos, Maria A;Ambrosioni, Juan;Miro, Josep M;Martinez, Esteban;Blanco, Jose L
10.1097/QAD.0000000000002643
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical characteristics, risk factors, and incidence of symptomatic coronavirus disease 2019 in a large cohort of adults living with HIV: a single-center, prospective observational study. [Abstract]: BACKGROUND: It is unclear how characteristics, risk factors, and incidence of coronavirus disease 2019 (COVID-...
33,012,988
Trends Food Sci Technol
Understanding the role of milk in regulating human homeostasis in the context of the COVID-19 global pandemic.
Although data from clinical observation have directly shown that children aged 0-14 years are less susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection than those who are between 15 and 64 years old, due to a lack of biological evidence of differences in cell entry receptors between age...
Journal Article
Ren, Guangxu;Cheng, Guangyan;Wang, Jiaqi
10.1016/j.tifs.2020.09.027
[ 0, 0, 1, 1, 0, 0, 0 ]
[Title]: Understanding the role of milk in regulating human homeostasis in the context of the COVID-19 global pandemic. [Abstract]: Although data from clinical observation have directly shown that children aged 0-14 years are less susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection tha...
32,952,269
Appl Math Model
Migration rate estimation in an epidemic network.
Most of the recent epidemic outbreaks in the world have as a trigger, a strong migratory component as has been evident in the recent Covid-19 pandemic. In this work we address the problem of migration of human populations and its effect on pathogen reinfections in the case of Dengue, using a Markov-chain susceptible-in...
dengue dynamics;human mobility;metapopulation model;migration;reinfection
Journal Article
Nunez-Lopez, M;Alarcon Ramos, L;Velasco-Hernandez, J X
10.1016/j.apm.2020.08.025
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Migration rate estimation in an epidemic network. [Abstract]: Most of the recent epidemic outbreaks in the world have as a trigger, a strong migratory component as has been evident in the recent Covid-19 pandemic. In this work we address the problem of migration of human populations and its effect on pathogen ...
32,916,258
Genomics
Identification of angiotensin-converting enzyme 2 (ACE2) protein as the potential biomarker in SARS-CoV-2 infection-related lung cancer using computational analyses.
COVID-19 is a pandemic that began to spread worldwide caused by SARS-CoV-2. Lung cancer patients are more susceptible to SARS-CoV-2 infection. The SARS-CoV-2 enters into the host by the ACE2 receptor. Thus, ACE2 is the key to understand the mechanism of SARS-CoV-2 infection. However, the lack of knowledge about the bio...
ace2;covid-19;lung cancer;potential biomarker;relationship of lung cancer and covid-19;mrna expression analysis
Journal Article
Samad, Abdus;Jafar, Tamanna;Rafi, Jahirul Hasnat
10.1016/j.ygeno.2020.09.002
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Identification of angiotensin-converting enzyme 2 (ACE2) protein as the potential biomarker in SARS-CoV-2 infection-related lung cancer using computational analyses. [Abstract]: COVID-19 is a pandemic that began to spread worldwide caused by SARS-CoV-2. Lung cancer patients are more susceptible to SARS-CoV-2 i...
32,427,219
Asian Bioeth Rev
'What is Inconvenient for You is Life-saving for Me': How Health Inequities are playing out during the COVID-19 Pandemic.
The COVID-19 pandemic has had a significant impact globally. Most affected, however, are those individuals and groups routinely disadvantaged by the social injustice created by the misdistribution of power, money, and resources. Simple measures that prevent the spread of COVID-19, such as frequent hand washing and soci...
covid-19;coronavirus pandemic;health inequity;social determinants of health;social disparities;social justice;structural injustice
Journal Article
Xafis, Vicki
10.1007/s41649-020-00119-1
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: 'What is Inconvenient for You is Life-saving for Me': How Health Inequities are playing out during the COVID-19 Pandemic. [Abstract]: The COVID-19 pandemic has had a significant impact globally. Most affected, however, are those individuals and groups routinely disadvantaged by the social injustice created by ...
32,824,787
Sensors (Basel)
DNA/RNA Electrochemical Biosensing Devices a Future Replacement of PCR Methods for a Fast Epidemic Containment.
Pandemics require a fast and immediate response to contain potential infectious carriers. In the recent 2020 Covid-19 worldwide pandemic, authorities all around the world have failed to identify potential carriers and contain it on time. Hence, a rapid and very sensitive testing method is required. Current diagnostic t...
dna;rna;electrochemical dna sensor;nucleic acid sensor;pathogen sensing;signal amplification
Journal Article;Review
Santhanam, Manikandan;Algov, Itay;Alfonta, Lital
10.3390/s20164648
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: DNA/RNA Electrochemical Biosensing Devices a Future Replacement of PCR Methods for a Fast Epidemic Containment. [Abstract]: Pandemics require a fast and immediate response to contain potential infectious carriers. In the recent 2020 Covid-19 worldwide pandemic, authorities all around the world have failed to i...
32,474,676
Int J Cardiovasc Imaging
Statement from the North American Society for Cardiovascular Imaging on imaging strategies to reduce the scarcity of healthcare resources during the COVID-19 outbreak.
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an evolving global pandemic that is predicted to strain healthcare resources at multiple locations throughout North America and the World. As of April 6, 2020, the apex of infection rates is predicted to occu...
covid19;cardiac ct;cardiac mri;cardiovascular imaging
Editorial
Kicska, Gregory;Litmanovich, Diana E;Ordovas, Karen G;Young, Phillip M;Dennie, Carole;Truong, Quynh A;Abbara, Suhny;Kirsch, Jacobo
10.1007/s10554-020-01861-1
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Statement from the North American Society for Cardiovascular Imaging on imaging strategies to reduce the scarcity of healthcare resources during the COVID-19 outbreak. [Abstract]: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an evolving global ...
32,815,850
J Orthop Trauma
Upscaling Virtual Fracture Clinic Use Is a Safe, Effective Measure in the Delivery of Trauma Care.
The Virtual Fracture Clinic (VFC) has proved beneficial in reducing footfall within the hospital setting, improving the cost of running a trauma service, while satisfying the majority of referred patients. The mandatory upscaling of telemedicine use, specifically the enhancement of the VFC, amidst the COVID-19 pandemic...
Journal Article
Hughes, Andrew J;Feeley, Iain H;Crowley, Michelle;Conlon, Breda;Merghani, Khalid;Sheehan, Eoin C
10.1097/BOT.0000000000001894
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Upscaling Virtual Fracture Clinic Use Is a Safe, Effective Measure in the Delivery of Trauma Care. [Abstract]: The Virtual Fracture Clinic (VFC) has proved beneficial in reducing footfall within the hospital setting, improving the cost of running a trauma service, while satisfying the majority of referred pati...
32,758,889
Med Hypotheses
Rethinking interleukin-6 blockade for treatment of COVID-19.
Interleukin-6 (IL-6) is a pleiotropic cytokine with effects in immune regulation, inflammation, and infection. The use of drugs that inhibit IL-6 biological activity has been proposed as a treatment for patients with Coronavirus Disease 2019 (COVID-19). The rationale for this approach includes commitment to the concept...
covid-19;il-6;il-6 blockade;il-6 inhibitors;il-6 receptor antagonists;sars-cov-2;tocilizumab
Journal Article
Scherger, S;Henao-Martinez, A;Franco-Paredes, C;Shapiro, L
10.1016/j.mehy.2020.110053
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Rethinking interleukin-6 blockade for treatment of COVID-19. [Abstract]: Interleukin-6 (IL-6) is a pleiotropic cytokine with effects in immune regulation, inflammation, and infection. The use of drugs that inhibit IL-6 biological activity has been proposed as a treatment for patients with Coronavirus Disease 2...
32,585,619
J Clin Virol
Evaluation of rapid antigen test for detection of SARS-CoV-2 virus.
BACKGROUND: The rapid diagnosis of Coronavirus Disease 2019 (COVID-19) patients is essential to reduce the disease spread. Rapid antigen detection (RAD) tests are available, however, there is scanty data on the performance of RAD tests. OBJECTIVE: To evaluate the performance of the commercially available BIOCREDIT COVI...
2019 novel coronavirus;covid-19;rt-pcr;rapid antigen detection;sars-cov-2;viral culture
Evaluation Study;Journal Article
Mak, Gannon Ck;Cheng, Peter Kc;Lau, Stephen Sy;Wong, Kitty Ky;Lau, C S;Lam, Edman Tk;Chan, Rickjason Cw;Tsang, Dominic Nc
10.1016/j.jcv.2020.104500
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Evaluation of rapid antigen test for detection of SARS-CoV-2 virus. [Abstract]: BACKGROUND: The rapid diagnosis of Coronavirus Disease 2019 (COVID-19) patients is essential to reduce the disease spread. Rapid antigen detection (RAD) tests are available, however, there is scanty data on the performance of RAD t...
32,379,887
J Infect Dis
T-Cell Subset Counts in Peripheral Blood Can Be Used as Discriminatory Biomarkers for Diagnosis and Severity Prediction of Coronavirus Disease 2019.
This study evaluated the significance of lymphocyte subset detection in peripheral blood in the diagnosis and prognosis of coronavirus disease 2019 (COVID-19). Our results revealed that CD3+ T cells, CD4+ T cells, CD8+ T cells, and natural killer cells were significantly decreased in patients with COVID-19. These patie...
sars-cov2;diagnosis;lymphocyte subsets;prognosis
Journal Article
Jiang, Mei;Guo, Yang;Luo, Qing;Huang, ZiKun;Zhao, Rui;Liu, ShuYuan;Le, AiPing;Li, JunMing;Wan, LaGen
10.1093/infdis/jiaa252
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: T-Cell Subset Counts in Peripheral Blood Can Be Used as Discriminatory Biomarkers for Diagnosis and Severity Prediction of Coronavirus Disease 2019. [Abstract]: This study evaluated the significance of lymphocyte subset detection in peripheral blood in the diagnosis and prognosis of coronavirus disease 2019 (C...
32,595,359
Turk J Biol
Potentials of plant-based substance to inhabit and probable cure for the COVID-19.
COVID-19 has been the most devastating pandemic in human history. Despite the highest scientific efforts and investments, a reliable and certified medication has yet to be developed regarding to immune or cure this virus. However, while synthetic medications are gaining the focus of attentions, it appears from a signif...
covid 19;hcov-229e;mers-cov;sars-cov;antiviral plants;coronaviruses;emodin;lycorine
Journal Article
Jahan, Israt;Onay, Ahmet
10.3906/biy-2005-114
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Potentials of plant-based substance to inhabit and probable cure for the COVID-19. [Abstract]: COVID-19 has been the most devastating pandemic in human history. Despite the highest scientific efforts and investments, a reliable and certified medication has yet to be developed regarding to immune or cure this v...
32,915,166
MMWR Morb Mortal Wkly Rep
Delay or Avoidance of Medical Care Because of COVID-19-Related Concerns - United States, June 2020.
Temporary disruptions in routine and nonemergency medical care access and delivery have been observed during periods of considerable community transmission of SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19) (1). However, medical care delay or avoidance might increase morbidity and mortality risk a...
Journal Article
Czeisler, Mark E;Marynak, Kristy;Clarke, Kristie E N;Salah, Zainab;Shakya, Iju;Thierry, JoAnn M;Ali, Nida;McMillan, Hannah;Wiley, Joshua F;Weaver, Matthew D;Czeisler, Charles A;Rajaratnam, Shantha M W;Howard, Mark E
10.15585/mmwr.mm6936a4
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Delay or Avoidance of Medical Care Because of COVID-19-Related Concerns - United States, June 2020. [Abstract]: Temporary disruptions in routine and nonemergency medical care access and delivery have been observed during periods of considerable community transmission of SARS-CoV-2, the virus that causes corona...
32,234,709
JMIR Public Health Surveill
Predicting COVID-19 Incidence Through Analysis of Google Trends Data in Iran: Data Mining and Deep Learning Pilot Study.
BACKGROUND: The recent global outbreak of coronavirus disease (COVID-19) is affecting many countries worldwide. Iran is one of the top 10 most affected countries. Search engines provide useful data from populations, and these data might be useful to analyze epidemics. Utilizing data mining methods on electronic resourc...
covid-19;google trends;lstm;coronavirus;incidence;linear regression;outbreak;pandemic;prediction;public health
Journal Article
Ayyoubzadeh, Seyed Mohammad;Ayyoubzadeh, Seyed Mehdi;Zahedi, Hoda;Ahmadi, Mahnaz;R Niakan Kalhori, Sharareh
10.2196/18828
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Predicting COVID-19 Incidence Through Analysis of Google Trends Data in Iran: Data Mining and Deep Learning Pilot Study. [Abstract]: BACKGROUND: The recent global outbreak of coronavirus disease (COVID-19) is affecting many countries worldwide. Iran is one of the top 10 most affected countries. Search engines ...
32,635,290
Healthcare (Basel)
Strategies for the Prevention of the Intra-Hospital Transmission of COVID-19: A Retrospective Cohort Study.
Coronavirus disease (COVID-19) has spread rapidly worldwide. We aimed to review the strategies used by our university hospital in Daegu (South Korea) to prevent the transmission of COVID-19 within our institution. We also investigated the actual situation at our hospital against the recommended guidelines. We conducted...
covid-19;hospital infection;isolation;mask;secondary infection
Journal Article
Chang, Min Cheol;Hur, Jian;Park, Donghwi
10.3390/healthcare8030195
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Strategies for the Prevention of the Intra-Hospital Transmission of COVID-19: A Retrospective Cohort Study. [Abstract]: Coronavirus disease (COVID-19) has spread rapidly worldwide. We aimed to review the strategies used by our university hospital in Daegu (South Korea) to prevent the transmission of COVID-19 w...
32,569,905
J Anxiety Disord
Fear of the coronavirus (COVID-19): Predictors in an online study conducted in March 2020.
Fear is an adaptive response in the presence of danger. However, when threat is uncertain and continuous, as in the current coronavirus disease (COVID-19) pandemic, fear can become chronic and burdensome. To identify predictors of fear of the coronavirus, we conducted an online survey (N = 439) three days after the Wor...
coronavirus;fear;health anxiety;intolerance of uncertainty;media
Journal Article;Research Support, Non-U.S. Gov't
Mertens, Gaetan;Gerritsen, Lotte;Duijndam, Stefanie;Salemink, Elske;Engelhard, Iris M
10.1016/j.janxdis.2020.102258
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Fear of the coronavirus (COVID-19): Predictors in an online study conducted in March 2020. [Abstract]: Fear is an adaptive response in the presence of danger. However, when threat is uncertain and continuous, as in the current coronavirus disease (COVID-19) pandemic, fear can become chronic and burdensome. To ...
32,243,607
J Med Virol
The presence of SARS-CoV-2 RNA in the feces of COVID-19 patients.
In December 2019, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in Wuhan, China, and has spread globally. However, the transmission route of SARS-CoV-2 has not been fully understood. In this study, we aimed to investigate SARS-CoV-2 shedding in the ...
coronavirus disease 2019;fecal-oral transmission;severe acute respiratory syndrome coronavirus 2;viral rna;viral shedding
Journal Article;Research Support, Non-U.S. Gov't
Chen, Yifei;Chen, Liangjun;Deng, Qiaoling;Zhang, Guqin;Wu, Kaisong;Ni, Lan;Yang, Yibin;Liu, Bing;Wang, Wei;Wei, Chaojie;Yang, Jiong;Ye, Guangming;Cheng, Zhenshun
10.1002/jmv.25825
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: The presence of SARS-CoV-2 RNA in the feces of COVID-19 patients. [Abstract]: In December 2019, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in Wuhan, China, and has spread globally. However, the transmission route of SARS-CoV-2 has not be...
32,692,666
Biosens Bioelectron
Multiplex reverse transcription loop-mediated isothermal amplification combined with nanoparticle-based lateral flow biosensor for the diagnosis of COVID-19.
The ongoing global pandemic (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a huge public health issue. Hence, we devised a multiplex reverse transcription loop-mediated isothermal amplification (mRT-LAMP) coupled with a nanoparticle-based lateral flow biosensor (LFB) ...
covid-19;lateral flow biosensor;multiplex reverse transcription loop-mediated isothermal amplification;rapid diagnosis;sars-cov-2
Journal Article;Validation Study
Zhu, Xiong;Wang, Xiaoxia;Han, Limei;Chen, Ting;Wang, Licheng;Li, Huan;Li, Sha;He, Lvfen;Fu, Xiaoying;Chen, Shaojin;Xing, Mei;Chen, Hai;Wang, Yi
10.1016/j.bios.2020.112437
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Multiplex reverse transcription loop-mediated isothermal amplification combined with nanoparticle-based lateral flow biosensor for the diagnosis of COVID-19. [Abstract]: The ongoing global pandemic (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a huge public ...
32,375,488
Eur Heart J Acute Cardiovasc Care
Respiratory management in severe acute respiratory syndrome coronavirus 2 infection.
The severe acute respiratory syndrome coronavirus 2 pandemic is to date affecting more than a million of patients and is challenging healthcare professionals around the world. Coronavirus disease 2019 may present with a wide range of clinical spectrum and severity, including severe interstitial pneumonia with high prev...
severe acute respiratory syndrome coronavirus 2;acute respiratory distress syndrome;coronavirus disease 2019;mechanical ventilation;oxygen therapy;respiratory failure
Journal Article
Price, Susanna;Singh, Suveer;Ledot, Stephane;Bianchi, Paolo;Hind, Matthew;Tavazzi, Guido;Vranckx, Pascal
10.1177/2048872620924613
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Respiratory management in severe acute respiratory syndrome coronavirus 2 infection. [Abstract]: The severe acute respiratory syndrome coronavirus 2 pandemic is to date affecting more than a million of patients and is challenging healthcare professionals around the world. Coronavirus disease 2019 may present w...
32,867,591
Otolaryngol Head Neck Surg
The Sinonasal Outcome Test-22 or European Position Paper: Which Is More Indicative of Imaging Results?
OBJECTIVE: The 22-item Sinonasal Outcome Test (SNOT-22) is a trusted measure of symptom severity in chronic rhinosinusitis. The European Position Paper on Rhinosinusitis (EPOS) provides widely accepted diagnostic criteria, which include sinonasal symptoms, their duration, and imaging results. Our objective was to compa...
covid-19;computed tomography;diagnostic assessment;patient-reported outcome measure;position statement;predictive value;rhinosinusitis;telemedicine
Journal Article;Observational Study
Zhou, Allen S;Prince, Anthony A;Maxfield, Alice Z;Corrales, C Eduardo;Shin, Jennifer J
10.1177/0194599820953834
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: The Sinonasal Outcome Test-22 or European Position Paper: Which Is More Indicative of Imaging Results? [Abstract]: OBJECTIVE: The 22-item Sinonasal Outcome Test (SNOT-22) is a trusted measure of symptom severity in chronic rhinosinusitis. The European Position Paper on Rhinosinusitis (EPOS) provides widely acc...
33,014,751
Indian J Otolaryngol Head Neck Surg
Emergence and Evolution of Olfactory and Gustatory Symptoms in Patients with COVID-19 in the Outpatient Setting.
The present study aimed at evaluating the prevalence of general and sinonasal symptoms in patients with olfactory symptoms and mild coronavirus disease-2019 (COVID-19) and determining the patterns in emergence and resolution of olfactory/gustatory symptoms relative to general and sinonassal symptoms. This was a prospec...
anosmia;covid-19;hypogeusia;hyposmia;sars-cov-2
Journal Article
Karimi-Galougahi, Mahboobeh;Safavi Naini, Ali;Ghorbani, Jahangir;Raad, Nasim;Raygani, Negar
10.1007/s12070-020-02166-4
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Emergence and Evolution of Olfactory and Gustatory Symptoms in Patients with COVID-19 in the Outpatient Setting. [Abstract]: The present study aimed at evaluating the prevalence of general and sinonasal symptoms in patients with olfactory symptoms and mild coronavirus disease-2019 (COVID-19) and determining th...
33,073,202
ACS Pharmacol Transl Sci
Ivermectin, Famotidine, and Doxycycline: A Suggested Combinatorial Therapeutic for the Treatment of COVID-19.
At times, combination therapy has proven to be very effective. While no cure is available to date, herein we put forward with rationale and supporting evidence that if administrated simultaneously, a combination of FDA-approved drugs comprising ivermectin, famotidine, and doxycycline may provide robust chemoprophylaxis...
Journal Article
Sen Gupta, Parth Sarthi;Rana, Malay Kumar
10.1021/acsptsci.0c00140
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Ivermectin, Famotidine, and Doxycycline: A Suggested Combinatorial Therapeutic for the Treatment of COVID-19. [Abstract]: At times, combination therapy has proven to be very effective. While no cure is available to date, herein we put forward with rationale and supporting evidence that if administrated simulta...
32,461,413
Indian J Ophthalmol
The impact of COVID-19 related lockdown on ophthalmology training programs in India - Outcomes of a survey.
Purpose: In 2020, in response to the emergence and global spread of the disease COVID-19, caused by a new variant of coronavirus 2019-nCoV, the government of India ordered a nationwide lockdown for 21 days, which was then extended to a total of over 50 days. The aim of this study is to assess the effect of the lockdown...
cataract training;sars;coronavirus;fellowship;medical education;post-graduation;residency training;resident;simulation;virtual reality
Journal Article
Mishra, Deepak;Nair, Akshay Gopinathan;Gandhi, Rashmin Anilkumar;Gogate, Parikshit J;Mathur, Satanshu;Bhushan, Prashant;Srivastav, Tanmay;Singh, Hemendra;Sinha, Bibhuti P;Singh, Mahendra Kumar
10.4103/ijo.IJO_1067_20
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The impact of COVID-19 related lockdown on ophthalmology training programs in India - Outcomes of a survey. [Abstract]: Purpose: In 2020, in response to the emergence and global spread of the disease COVID-19, caused by a new variant of coronavirus 2019-nCoV, the government of India ordered a nationwide lockdo...
33,017,616
J Hosp Infect
Gravity steam reprocessing in healthcare facilities for the reuse of N95 respirators.
BACKGROUND: Coronavirus disease 2019 (COVID-19) has significantly impacted the health of millions of people around the world. The shortage of personal protective equipment, including N95 respirators, in hospital facilities has put frontline healthcare professionals at high risk for contracting this virus. AIM: To devel...
covid-19;filtration;n95 respirators;reprocessing;reuse;steam
Comparative Study;Journal Article
Aljabo, A;Mueller, E;Abdul-Azeez, D;Hoare, T;Jain, A
10.1016/j.jhin.2020.09.032
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Gravity steam reprocessing in healthcare facilities for the reuse of N95 respirators. [Abstract]: BACKGROUND: Coronavirus disease 2019 (COVID-19) has significantly impacted the health of millions of people around the world. The shortage of personal protective equipment, including N95 respirators, in hospital f...
32,574,237
Front Pharmacol
Reducing the Fatality Rate of COVID-19 by Applying Clinical Insights From Immuno-Oncology and Lung Transplantation.
There is an urgent need to identify effective strategies that can stop or reverse the inflammatory process that causes acute lung injury, ARDS, and multi-organ failure in COVID-19. Adaptive clinical trials with parallel enrollment to different arms each evaluating a rationally designed combination modality could provid...
2019-ncov;covid-19;acute lung injury;acute respiratory distress syndrome;cytokine release syndrome;systemic capillary leak
Journal Article;Review
Uckun, Fatih M
10.3389/fphar.2020.00796
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Reducing the Fatality Rate of COVID-19 by Applying Clinical Insights From Immuno-Oncology and Lung Transplantation. [Abstract]: There is an urgent need to identify effective strategies that can stop or reverse the inflammatory process that causes acute lung injury, ARDS, and multi-organ failure in COVID-19. Ad...
32,990,119
J Med Eng Technol
Return to school in the COVID-19 era: considerations for temperature measurement.
COVID-19 pandemics required a reorganisation of social spaces to prevent the spread of the virus. Due to the common presence of fever in the symptomatic patients, temperature measurement is one of the most common screening protocols. Indeed, regulations in many countries require temperature measurements before entering...
covid-19;fever;infra-red thermal camera;non-contact thermometry;temperature
Journal Article
Buoite Stella, Alex;Manganotti, Paolo;Furlanis, Giovanni;Accardo, Agostino;Ajcevic, Milos
10.1080/03091902.2020.1822941
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Return to school in the COVID-19 era: considerations for temperature measurement. [Abstract]: COVID-19 pandemics required a reorganisation of social spaces to prevent the spread of the virus. Due to the common presence of fever in the symptomatic patients, temperature measurement is one of the most common scre...
32,338,298
Eur Arch Otorhinolaryngol
The After Diagnosis Head and Neck cancer-specific Patient Concerns Inventory (HaNC-AD) as a pre-treatment preparation aid during the COVID-19 pandemic.
The coronavirus disease 2019 pandemic has resulted in new challenges for clinicians, head and neck cancer (HNC) patients and carers. There is evidence that the current crisis is affecting the management of HNC patients. Most healthcare systems have introduced remote consultations to decrease the risk of coronavirus inf...
coronavirus;head and neck cancer;patient concerns inventory;sars-cov-2
Journal Article
Kanatas, Anastasios;Rogers, S N
10.1007/s00405-020-05995-9
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The After Diagnosis Head and Neck cancer-specific Patient Concerns Inventory (HaNC-AD) as a pre-treatment preparation aid during the COVID-19 pandemic. [Abstract]: The coronavirus disease 2019 pandemic has resulted in new challenges for clinicians, head and neck cancer (HNC) patients and carers. There is evide...
32,417,195
Ann Thorac Surg
Pandemic Recovery Using a COVID-Minimal Cancer Surgery Pathway.
The coronavirus disease 2019 (COVID-19) pandemic has created unprecedented disruption in health care delivery around the world. In an effort to prevent hospital-acquired COVID-19 infections, most hospitals have severely curtailed elective surgery, performing only surgeries if the patient's survival or permanent functio...
Journal Article
Boffa, Daniel J;Judson, Benjamin L;Billingsley, Kevin G;Galetta, Domenico;Fontanez, Paul;Odermatt, Craig;Lindner, Kristy;Mitchell, Marci R;Henderson, Cara M;Carafeno, Tracy;Pinto, Josephine;Wagner, Jane A;Ancuta, Michael M;Beley, Peggy;Turner, Anne L;Banack, Trevor;Laurans, Maxwell S;Johnson, Dirk C;Yoo, Peter S;Morton...
10.1016/j.athoracsur.2020.05.003
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Pandemic Recovery Using a COVID-Minimal Cancer Surgery Pathway. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic has created unprecedented disruption in health care delivery around the world. In an effort to prevent hospital-acquired COVID-19 infections, most hospitals have severely curtailed elect...
32,591,166
Ultrasound Med Biol
A Review of Early Experience in Lung Ultrasound in the Diagnosis and Management of COVID-19.
A novel coronavirus (2019-nCoV) was identified as the cause of a cluster of pneumonia in Wuhan, China, at the end of 2019. Since then more than eight million confirmed cases of coronavirus disease 2019 (COVID-19) have been reported around the globe. The current gold standard for etiologic diagnosis is reverse transcrip...
covid-19;coronavirus;lung imaging;lung ultrasound;pneumonia;point of care ultrasound (pocus)
Journal Article;Review
Sultan, Laith R;Sehgal, Chandra M
10.1016/j.ultrasmedbio.2020.05.012
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: A Review of Early Experience in Lung Ultrasound in the Diagnosis and Management of COVID-19. [Abstract]: A novel coronavirus (2019-nCoV) was identified as the cause of a cluster of pneumonia in Wuhan, China, at the end of 2019. Since then more than eight million confirmed cases of coronavirus disease 2019 (COV...
32,544,492
Chest
Lessons on Outbreak Preparedness From the Cleveland Clinic.
Disasters, including infectious disease outbreaks, are inevitable. Hospitals need to plan in advance to ensure that their systems can adapt to a rapidly changing environment if necessary. This review provides an overview of 10 general principles that hospitals and health-care systems should consider when developing dis...
review;stress;topics in practice management;viral disease
Journal Article;Review
Orsini, Erica;Mireles-Cabodevila, Eduardo;Ashton, Rendell;Khouli, Hassan;Chaisson, Neal
10.1016/j.chest.2020.06.009
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Lessons on Outbreak Preparedness From the Cleveland Clinic. [Abstract]: Disasters, including infectious disease outbreaks, are inevitable. Hospitals need to plan in advance to ensure that their systems can adapt to a rapidly changing environment if necessary. This review provides an overview of 10 general prin...
33,075,298
Lancet Respir Med
Cytokine elevation in severe and critical COVID-19: a rapid systematic review, meta-analysis, and comparison with other inflammatory syndromes.
The description of a so-called cytokine storm in patients with COVID-19 has prompted consideration of anti-cytokine therapies, particularly interleukin-6 antagonists. However, direct systematic comparisons of COVID-19 with other critical illnesses associated with elevated cytokine concentrations have not been reported....
Journal Article;Meta-Analysis;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't;Systematic Review
Leisman, Daniel E;Ronner, Lukas;Pinotti, Rachel;Taylor, Matthew D;Sinha, Pratik;Calfee, Carolyn S;Hirayama, Alexandre V;Mastroiani, Fiore;Turtle, Cameron J;Harhay, Michael O;Legrand, Matthieu;Deutschman, Clifford S
10.1016/S2213-2600(20)30404-5
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Cytokine elevation in severe and critical COVID-19: a rapid systematic review, meta-analysis, and comparison with other inflammatory syndromes. [Abstract]: The description of a so-called cytokine storm in patients with COVID-19 has prompted consideration of anti-cytokine therapies, particularly interleukin-6 a...
32,347,997
Head Neck
Self-removing passive drain to facilitate postoperative care via telehealth during the COVID-19 pandemic.
BACKGROUND: Telehealth postoperative visits are an attractive strategy to minimize exposure, especially during the SARS-CoV-2 (COVID-19) pandemic. The use of a surgical drain often prevents this minimal-exposure approach in that patients return to the outpatient clinic for drain removal. METHODS AND RESULTS: Following ...
covid-19;drainage;head and neck neoplasms;neck dissection;telemedicine
Case Reports;Journal Article
Qualliotine, Jesse R;Orosco, Ryan K
10.1002/hed.26203
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Self-removing passive drain to facilitate postoperative care via telehealth during the COVID-19 pandemic. [Abstract]: BACKGROUND: Telehealth postoperative visits are an attractive strategy to minimize exposure, especially during the SARS-CoV-2 (COVID-19) pandemic. The use of a surgical drain often prevents thi...
32,854,983
J Subst Abuse Treat
Adaptation of contingency management for stimulant use disorder during the COVID-19 pandemic.
The current coronavirus disease (COVID-19) pandemic has rapidly spread across the world. Individuals with stimulant use disorder are a vulnerable population, who are particularly at risk of negative outcomes during this pandemic due to several risk factors, including mental and physical comorbidities, weakened immune r...
amphetamine;covid-19;cocaine;contingency management;stimulant
Journal Article
Zastepa, Evelyn;Sun, Jane C;Clune, Jennifer;Mathew, Nickie
10.1016/j.jsat.2020.108102
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Adaptation of contingency management for stimulant use disorder during the COVID-19 pandemic. [Abstract]: The current coronavirus disease (COVID-19) pandemic has rapidly spread across the world. Individuals with stimulant use disorder are a vulnerable population, who are particularly at risk of negative outcom...
32,633,713
Emerg Infect Dis
Coronavirus Disease Exposure and Spread from Nightclubs, South Korea.
At least 246 cases of coronavirus disease (COVID-19) have been linked to nightclubs in Seoul, South Korea. During the April 30-May 5 holiday, young adults from across the country who visited nightclubs in Seoul contracted COVID-19 and spread it nationally. Nightclubs were temporarily closed to limit COVID-19 spread.
2019 novel coronavirus disease;covid-19;sars;sars-cov-2;seoul;south korea;coronavirus;coronavirus disease;nightclubs;outbreak;respiratory infections;severe acute respiratory syndrome coronavirus 2;viruses;zoonoses
Letter
Kang, Cho Ryok;Lee, Jin Yong;Park, Yoojin;Huh, In Sil;Ham, Hyon Jeen;Han, Jin Kyeong;Kim, Jung Il;Na, Baeg Ju
10.3201/eid2610.202573
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Coronavirus Disease Exposure and Spread from Nightclubs, South Korea. [Abstract]: At least 246 cases of coronavirus disease (COVID-19) have been linked to nightclubs in Seoul, South Korea. During the April 30-May 5 holiday, young adults from across the country who visited nightclubs in Seoul contracted COVID-1...
32,298,686
Urology
Teleurology in the Time of Covid-19 Pandemic: Here to Stay?
OBJECTIVE: To assess the implementation and outcomes of telemedicine in a Department of Urology in Northern Italy during the outbreak of the Covid-19 pandemic. METHODS: All the outpatient clinical activities during the 4 weeks following the national lockdown (March 9-April 3, 2020) in the Department of Urology of the T...
Journal Article
Luciani, Lorenzo Giuseppe;Mattevi, Daniele;Cai, Tommaso;Giusti, Guido;Proietti, Silvia;Malossini, Gianni
10.1016/j.urology.2020.04.004
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Teleurology in the Time of Covid-19 Pandemic: Here to Stay? [Abstract]: OBJECTIVE: To assess the implementation and outcomes of telemedicine in a Department of Urology in Northern Italy during the outbreak of the Covid-19 pandemic. METHODS: All the outpatient clinical activities during the 4 weeks following th...
32,758,298
Trials
A phase II, single-center, double-blind, randomized placebo-controlled trial to explore the efficacy and safety of intravenous melatonin in patients with COVID-19 admitted to the intensive care unit (MelCOVID study): a structured summary of a study protocol for a randomized controlled trial.
OBJECTIVES: * Primary objective: to evaluate the effect of intravenous melatonin (IVM) on mortality in adult patients admitted to the intensive care unit (ICU) with COVID-19. * Secondary objectives: To evaluate the effect of IVM on ICU length of stay. To evaluate the effect of IVM on the length of mechanical ventilatio...
ards;covid-19;randomized controlled trial;inflammation;intensive care;melatonin;protocol;treatment
Clinical Trial Protocol;Clinical Trial, Phase II;Letter
Rodriguez-Rubio, Miguel;Figueira, Juan Carlos;Acuna-Castroviejo, Dario;Borobia, Alberto M;Escames, Germaine;de la Oliva, Pedro
10.1186/s13063-020-04632-4
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: A phase II, single-center, double-blind, randomized placebo-controlled trial to explore the efficacy and safety of intravenous melatonin in patients with COVID-19 admitted to the intensive care unit (MelCOVID study): a structured summary of a study protocol for a randomized controlled trial. [Abstract]: OBJECT...
32,458,400
J Cardiovasc Transl Res
Implications for Neuromodulation Therapy to Control Inflammation and Related Organ Dysfunction in COVID-19.
COVID-19 is a syndrome that includes more than just isolated respiratory disease, as severe acute respiratory syndrome-coronavirus 2 (SARS-CoV2) also interacts with the cardiovascular, nervous, renal, and immune system at multiple levels, increasing morbidity in patients with underlying cardiometabolic conditions and i...
ace2;covid-19;sars-cov2;vagus;vagus nerve stimulation
Journal Article;Research Support, N.I.H., Extramural;Review
Fudim, Marat;Qadri, Yawar J;Ghadimi, Kamrouz;MacLeod, David B;Molinger, Jeroen;Piccini, Jonathan P;Whittle, John;Wischmeyer, Paul E;Patel, Manesh R;Ulloa, Luis
10.1007/s12265-020-10031-6
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Implications for Neuromodulation Therapy to Control Inflammation and Related Organ Dysfunction in COVID-19. [Abstract]: COVID-19 is a syndrome that includes more than just isolated respiratory disease, as severe acute respiratory syndrome-coronavirus 2 (SARS-CoV2) also interacts with the cardiovascular, nervou...
32,733,921
Front Cardiovasc Med
High Inflammatory Burden: A Potential Cause of Myocardial Injury in Critically Ill Patients With COVID-19.
Background: Myocardial injury is a severe complication of novel coronavirus disease (COVID-19), and inflammation has been suggested as a potential cause of myocardial injury. However, the correlation of myocardial injury with inflammation in COVID-19 patients has not been revealed so far. Method: This retrospective sin...
covid-19;in-icu mortality;critical patients;inflammation;myocardial injury
Journal Article
Song, Yanjun;Gao, Peng;Ran, Tian;Qian, Hao;Guo, Fan;Chang, Long;Wu, Wei;Zhang, Shuyang
10.3389/fcvm.2020.00128
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: High Inflammatory Burden: A Potential Cause of Myocardial Injury in Critically Ill Patients With COVID-19. [Abstract]: Background: Myocardial injury is a severe complication of novel coronavirus disease (COVID-19), and inflammation has been suggested as a potential cause of myocardial injury. However, the corr...
32,724,685
Case Rep Infect Dis
Coronavirus Disease 2019 (COVID-19) Manifestation as Acute Myocardial Infarction in a Young, Healthy Male.
Although a large part of the symptomology of coronavirus disease 2019 (COVID-19) has been attributed to its effects in the lungs, the virus has also been shown to cause extensive cardiovascular complications in a small subset of patients. In this case report, we describe a 29-year-old nonobese hospital food service ass...
Case Reports
Juthani, Prerak;Bhojwani, Rohan;Gupta, Neil
10.1155/2020/8864985
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Coronavirus Disease 2019 (COVID-19) Manifestation as Acute Myocardial Infarction in a Young, Healthy Male. [Abstract]: Although a large part of the symptomology of coronavirus disease 2019 (COVID-19) has been attributed to its effects in the lungs, the virus has also been shown to cause extensive cardiovascula...
32,599,281
Int J Infect Dis
Comparing COVID-19 and the 1918-19 influenza pandemics in the United Kingdom.
We compared the COVID-19 and 1918-19 influenza pandemics in the United Kingdom. We found that the ongoing COVID-19 wave of infection matched the major wave of the 1918-19 influenza pandemic surprisingly well, with both reaching similar magnitudes (in terms of estimated weekly new infections) and spending the same durat...
1918-19 influenza;covid-19;multiple waves;united kingdom;years of life lost
Comparative Study;Journal Article
He, Daihai;Zhao, Shi;Li, Yingke;Cao, Peihua;Gao, Daozhou;Lou, Yijun;Yang, Lin
10.1016/j.ijid.2020.06.075
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Comparing COVID-19 and the 1918-19 influenza pandemics in the United Kingdom. [Abstract]: We compared the COVID-19 and 1918-19 influenza pandemics in the United Kingdom. We found that the ongoing COVID-19 wave of infection matched the major wave of the 1918-19 influenza pandemic surprisingly well, with both re...
32,448,770
Eur J Intern Med
Off-label use of tocilizumab for the treatment of SARS-CoV-2 pneumonia in Milan, Italy.
BACKGROUND: Tocilizumab, a humanized monoclonal antibody, targets IL-6 receptors blocking downstream pro-inflammatory effects of IL-6. In preliminary reports it was suggested to be beneficial in patients with severe COVID-19. METHODS: In this open-label prospective study we describe clinical characteristics and outcome...
covid-19;il-6 inhibitors;tocilizumab
Journal Article
Morena, Valentina;Milazzo, Laura;Oreni, Letizia;Bestetti, Giovanna;Fossali, Tommaso;Bassoli, Cinzia;Torre, Alessandro;Cossu, Maria Vittoria;Minari, Caterina;Ballone, Elisabetta;Perotti, Andrea;Mileto, Davide;Niero, Fosca;Merli, Stefania;Foschi, Antonella;Vimercati, Stefania;Rizzardini, Giuliano;Sollima, Salvatore;Brada...
10.1016/j.ejim.2020.05.011
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Off-label use of tocilizumab for the treatment of SARS-CoV-2 pneumonia in Milan, Italy. [Abstract]: BACKGROUND: Tocilizumab, a humanized monoclonal antibody, targets IL-6 receptors blocking downstream pro-inflammatory effects of IL-6. In preliminary reports it was suggested to be beneficial in patients with se...
32,316,857
Trop Doct
COVID-19 and orthopaedic surgeons: the Indian scenario.
The emergence of COVID-19 has impacted orthopaedic surgery worldwide. India, with its large population and limited health resources, will be overwrought over the coming days due to the number of cases of critically ill patients with COVID-19. It is important to understand the challenges for orthopaedic (and other) surg...
covid-19;coronavirus disease;orthopaedics;surgery;trauma
Journal Article
Jain, Vijay K;Vaishya, Raju
10.1177/0049475520921616
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 and orthopaedic surgeons: the Indian scenario. [Abstract]: The emergence of COVID-19 has impacted orthopaedic surgery worldwide. India, with its large population and limited health resources, will be overwrought over the coming days due to the number of cases of critically ill patients with COVID-19. ...
32,837,951
Indian J Otolaryngol Head Neck Surg
Effect of Covid-19 in Otorhinolaryngology Practice: A Review.
Otorhinolaryngological manifestations are common among patients suffering from COVID-19. This study provides a brief and precise review of the current knowledge regarding COVID-19 including disease transmission and clinical characteristics. This article aims to review the otolaryngologist experience treating patients i...
covid-19;ppe;urt
Journal Article
Grag, Kanchan;Kumar Shubhanshu
10.1007/s12070-020-02040-3
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Effect of Covid-19 in Otorhinolaryngology Practice: A Review. [Abstract]: Otorhinolaryngological manifestations are common among patients suffering from COVID-19. This study provides a brief and precise review of the current knowledge regarding COVID-19 including disease transmission and clinical characteristi...
32,963,091
J Am Soc Nephrol
Extracorporeal Treatment for Chloroquine, Hydroxychloroquine, and Quinine Poisoning: Systematic Review and Recommendations from the EXTRIP Workgroup.
BACKGROUND: Although chloroquine, hydroxychloroquine, and quinine are used for a range of medical conditions, recent research suggested a potential role in treating COVID-19. The resultant increase in prescribing was accompanied by an increase in adverse events, including severe toxicity and death. The Extracorporeal T...
covid-19;chloroquine;hydroxychloroquine;quinine;hemodialysis;hemofiltration
Journal Article;Systematic Review
Berling, Ingrid;King, Joshua D;Shepherd, Greene;Hoffman, Robert S;Alhatali, Badria;Lavergne, Valery;Roberts, Darren M;Gosselin, Sophie;Wilson, Gabrielle;Nolin, Thomas D;Ghannoum, Marc
10.1681/ASN.2020050564
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Extracorporeal Treatment for Chloroquine, Hydroxychloroquine, and Quinine Poisoning: Systematic Review and Recommendations from the EXTRIP Workgroup. [Abstract]: BACKGROUND: Although chloroquine, hydroxychloroquine, and quinine are used for a range of medical conditions, recent research suggested a potential r...
32,436,101
J Neurol
Neurological manifestations associated with COVID-19: a review and a call for action.
While the epidemic of Coronavirus disease 2019 (COVID-19) continues to spread globally, more and more evidences are collected about the presence of neurological manifestations and symptoms associated with it. A systematic review has been performed of papers published until 5 April 2020. 29 papers related to neurologica...
covid-19;central nervous system;neurocovid;neurological symptoms;peripheral nervous system;research
Journal Article;Systematic Review
Leonardi, Matilde;Padovani, Alessandro;McArthur, Justin C
10.1007/s00415-020-09896-z
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Neurological manifestations associated with COVID-19: a review and a call for action. [Abstract]: While the epidemic of Coronavirus disease 2019 (COVID-19) continues to spread globally, more and more evidences are collected about the presence of neurological manifestations and symptoms associated with it. A sy...
32,208,917
Emerg Microbes Infect
The different clinical characteristics of corona virus disease cases between children and their families in China - the character of children with COVID-19.
This study aims to analyze the different clinical characteristics between children and their families infected with severe acute respiratory syndrome coronavirus 2. Clinical data from nine children and their 14 families were collected, including general status, clinical, laboratory test, and imaging characteristics. Al...
coronavirus;children;clinical characteristics;corona virus diseases-19 (covid-19);severe acute respiratory syndrome coronavirus 2 (sars-cov-2)
Comparative Study;Journal Article
Su, Liang;Ma, Xiang;Yu, Huafeng;Zhang, Zhaohua;Bian, Pengfei;Han, Yuling;Sun, Jing;Liu, Yanqin;Yang, Chun;Geng, Jin;Zhang, Zhongfa;Gai, Zhongtao
10.1080/22221751.2020.1744483
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: The different clinical characteristics of corona virus disease cases between children and their families in China - the character of children with COVID-19. [Abstract]: This study aims to analyze the different clinical characteristics between children and their families infected with severe acute respiratory s...
32,766,453
Glob Health Res Policy
Digital technology applications for contact tracing: the new promise for COVID-19 and beyond?
Among the most critical strategies in the fight against the Corona Virus Disease (COVID-19) is the rapid tracing and notification of potentially infected persons. Several nations have implemented mobile software applications ("apps") to alert persons exposed to the coronavirus. The expected advantages of this new techn...
covid-19;digital health technology;health policy;population health;program implementation
Journal Article
Owusu, Priscilla N
10.1186/s41256-020-00164-1
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Digital technology applications for contact tracing: the new promise for COVID-19 and beyond? [Abstract]: Among the most critical strategies in the fight against the Corona Virus Disease (COVID-19) is the rapid tracing and notification of potentially infected persons. Several nations have implemented mobile so...
32,634,079
Curr Pharm Des
The Role of Chloroquine and Hydroxychloroquine in Immune Regulation and Diseases.
Chloroquine (CQ) and hydroxychloroquine (HCQ) are derivatives of the heterocyclic aromatic compound quinoline. These economical compounds have been used as antimalarial agents for many years. Currently, they are used as monotherapy or in conjunction with other therapies for the treatment of autoimmune diseases such as ...
covid-19;chloroquine;autoimmune diseases;autophagy;cancer;coronavirus;hydroxychloroquine;inflammation
Journal Article;Research Support, Non-U.S. Gov't;Review
Martinez, Gricelis P;Zabaleta, Mercedes E;Di Giulio, Camilo;Charris, Jaime E;Mijares, Michael R
10.2174/1381612826666200707132920
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The Role of Chloroquine and Hydroxychloroquine in Immune Regulation and Diseases. [Abstract]: Chloroquine (CQ) and hydroxychloroquine (HCQ) are derivatives of the heterocyclic aromatic compound quinoline. These economical compounds have been used as antimalarial agents for many years. Currently, they are used ...
32,931,443
JMIR Med Inform
A Computer-Interpretable Guideline for COVID-19: Rapid Development and Dissemination.
BACKGROUND: COVID-19 is a global pandemic that is affecting more than 200 countries worldwide. Efficient diagnosis and treatment are crucial to combat the disease. Computer-interpretable guidelines (CIGs) can aid the broad global adoption of evidence-based diagnosis and treatment knowledge. However, currently, no inter...
cdss;covid-19;guideline definition language;algorithm;development;dissemination;electronic health record;guideline;openehr
Journal Article
Nan, Shan;Tang, Tianhua;Feng, Hongshuo;Wang, Yijie;Li, Mengyang;Lu, Xudong;Duan, Huilong
10.2196/21628
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: A Computer-Interpretable Guideline for COVID-19: Rapid Development and Dissemination. [Abstract]: BACKGROUND: COVID-19 is a global pandemic that is affecting more than 200 countries worldwide. Efficient diagnosis and treatment are crucial to combat the disease. Computer-interpretable guidelines (CIGs) can aid ...
32,335,406
Sci Total Environ
Factors associated with negative conversion of viral RNA in patients hospitalized with COVID-19.
Factors associated with negative conversion of SARS-CoV-2 RNA in hospitalized patients have not yet been systematically determined. We conducted a retrospective cohort study of COVID-19 patients in Qingdao, China. Both univariate and multivariate analysis were performed to identify independent factors for time to viral...
coronavirus disease 2019 (covid-19);hazard ratio;negative conversion;severe acute respiratory syndrome coronavirus 2 (sars-cov-2)
Journal Article
Hu, Xiaowen;Xing, Yuhan;Jia, Jing;Ni, Wei;Liang, Jiwei;Zhao, Dan;Song, Xin;Gao, Ruqin;Jiang, Fachun
10.1016/j.scitotenv.2020.138812
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Factors associated with negative conversion of viral RNA in patients hospitalized with COVID-19. [Abstract]: Factors associated with negative conversion of SARS-CoV-2 RNA in hospitalized patients have not yet been systematically determined. We conducted a retrospective cohort study of COVID-19 patients in Qing...
32,756,893
J Public Health (Oxf)
Relationship of George Floyd protests to increases in COVID-19 cases using event study methodology.
BACKGROUND: Protests ignited by the George Floyd incident were examined for any significant impact on COVID-19 infection rates in select US cities. METHODS: Eight US cities were studied in which protestors in the tens of thousands were reported. Only cities that reside in states whose stay-at-home orders had been resci...
covid-19;public health;social distancing
Journal Article
Valentine, Randall;Valentine, Dawn;Valentine, Jimmie L
10.1093/pubmed/fdaa127
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Relationship of George Floyd protests to increases in COVID-19 cases using event study methodology. [Abstract]: BACKGROUND: Protests ignited by the George Floyd incident were examined for any significant impact on COVID-19 infection rates in select US cities. METHODS: Eight US cities were studied in which prot...