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33,005,122
Yale J Biol Med
A Case for Girl-child Education to Prevent and Curb the Impact of Emerging Infectious Diseases Epidemics.
Not only do epidemics such as HIV/AIDS, Ebola Virus Disease (EVD), and the current Coronavirus Disease (COVID-19) cause the loss of millions of lives, but they also cost the global economy billions of dollars. Consequently, there is an urgent need to formulate interventions that will help control their spread and impac...
girl-child;education;epidemics;health;pandemics;social determinant
Journal Article;Review
Frimpong, Shadrack;Paintsil, Elijah
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A Case for Girl-child Education to Prevent and Curb the Impact of Emerging Infectious Diseases Epidemics. [Abstract]: Not only do epidemics such as HIV/AIDS, Ebola Virus Disease (EVD), and the current Coronavirus Disease (COVID-19) cause the loss of millions of lives, but they also cost the global economy bill...
32,864,126
Ann Med Surg (Lond)
COVID-19 and paediatric dentistry- traversing the challenges. A narrative review.
The coronavirus disease (COVID-19) pandemic has become a major global public health emergency with a focus on preventing the spread of this virus for controlling this crisis. A dental setting is at a high risk of cross infection amid patients and dental practitioner's owing to the spread of infection via droplets suspe...
covid-19;dental education;dental practice management;infection control;peadiatric dentistry
Journal Article;Review
Shah, Saleha
10.1016/j.amsu.2020.08.007
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 and paediatric dentistry- traversing the challenges. A narrative review. [Abstract]: The coronavirus disease (COVID-19) pandemic has become a major global public health emergency with a focus on preventing the spread of this virus for controlling this crisis. A dental setting is at a high risk of cros...
32,762,368
J Investig Med High Impact Case Rep
Prolonged QT Interval in a Patient With Coronavirus Disease-2019: Beyond Hydroxychloroquine and Azithromycin.
Recent reports have suggested an increased risk of QT prolongation and subsequent life-threatening ventricular arrhythmias, particularly torsade de pointes, in patients with coronavirus disease-2019 (COVID-19) treated with hydroxychloroquine and azithromycin. In this article, we report the case of a 75-year-old female ...
covid-19;cardiac arrhythmia;prolonged qtc;torsade de pointes
Case Reports;Journal Article
Anupama, B K;Adhikari, Soumya;Chaudhuri, Debanik
10.1177/2324709620948407
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Prolonged QT Interval in a Patient With Coronavirus Disease-2019: Beyond Hydroxychloroquine and Azithromycin. [Abstract]: Recent reports have suggested an increased risk of QT prolongation and subsequent life-threatening ventricular arrhythmias, particularly torsade de pointes, in patients with coronavirus dis...
32,848,152
Nat Commun
The geography of COVID-19 spread in Italy and implications for the relaxation of confinement measures.
The pressing need to restart socioeconomic activities locked-down to control the spread of SARS-CoV-2 in Italy must be coupled with effective methodologies to selectively relax containment measures. Here we employ a spatially explicit model, properly attentive to the role of inapparent infections, capable of: estimatin...
Journal Article;Research Support, Non-U.S. Gov't
Bertuzzo, Enrico;Mari, Lorenzo;Pasetto, Damiano;Miccoli, Stefano;Casagrandi, Renato;Gatto, Marino;Rinaldo, Andrea
10.1038/s41467-020-18050-2
[ 0, 0, 1, 0, 1, 1, 0 ]
[Title]: The geography of COVID-19 spread in Italy and implications for the relaxation of confinement measures. [Abstract]: The pressing need to restart socioeconomic activities locked-down to control the spread of SARS-CoV-2 in Italy must be coupled with effective methodologies to selectively relax containment measure...
32,240,095
JMIR Public Health Surveill
Emergence of a Novel Coronavirus (COVID-19): Protocol for Extending Surveillance Used by the Royal College of General Practitioners Research and Surveillance Centre and Public Health England.
BACKGROUND: The Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC) and Public Health England (PHE) have successfully worked together on the surveillance of influenza and other infectious diseases for over 50 years, including three previous pandemics. With the emergence of the internati...
covid-19;sars-cov-2;computerized;coronavirus;general practice;infections;medical record systems;pandemic;records as topic;sentinel surveillance;serology;surveillance
Journal Article
de Lusignan, Simon;Lopez Bernal, Jamie;Zambon, Maria;Akinyemi, Oluwafunmi;Amirthalingam, Gayatri;Andrews, Nick;Borrow, Ray;Byford, Rachel;Charlett, Andre;Dabrera, Gavin;Ellis, Joanna;Elliot, Alex J;Feher, Michael;Ferreira, Filipa;Krajenbrink, Else;Leach, Jonathan;Linley, Ezra;Liyanage, Harshana;Okusi, Cecilia;Ramsay, M...
10.2196/18606
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Emergence of a Novel Coronavirus (COVID-19): Protocol for Extending Surveillance Used by the Royal College of General Practitioners Research and Surveillance Centre and Public Health England. [Abstract]: BACKGROUND: The Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC) and Pu...
32,582,745
Front Med (Lausanne)
Management of Hemoglobin Disorders During the COVID-19 Pandemic.
The coronavirus disease 2019 (COVID-19) is an emerging infectious disease that has become a global public health concern after being first reported in China and has subsequently spread worldwide. It causes mild to severe respiratory illness with some flu-like symptoms. The causal virus behind this disease, SARS-CoV-2 (...
covid-19;sars-cov-2;clinical management;hemoglobin;hemoglobinopathies;iron chelation therapy;sickle cell diseases;thalassemia
Journal Article;Review
Chowdhury, Sanjana Fatema;Anwar, Saeed
10.3389/fmed.2020.00306
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Management of Hemoglobin Disorders During the COVID-19 Pandemic. [Abstract]: The coronavirus disease 2019 (COVID-19) is an emerging infectious disease that has become a global public health concern after being first reported in China and has subsequently spread worldwide. It causes mild to severe respiratory i...
32,946,347
Telemed J E Health
Considerations on the Implementation of the Telemedicine System Encountered with Stakeholders' Resistance in COVID-19 Pandemic.
Background: Non-face-to-face consultation, which ensures physical distance between patients and doctors, is increasing as a substitute mode for dealing with highly infectious diseases. Korea, with its remarkable Information and Communications Technology infrastructure, introduced telemedicine in 1988, yet it has not be...
covid-19;resistance;stakeholder;telemedicine
Journal Article
Kim, Ah Young;Choi, Woo Seok
10.1089/tmj.2020.0293
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Considerations on the Implementation of the Telemedicine System Encountered with Stakeholders' Resistance in COVID-19 Pandemic. [Abstract]: Background: Non-face-to-face consultation, which ensures physical distance between patients and doctors, is increasing as a substitute mode for dealing with highly infecti...
32,409,437
Cleve Clin J Med
Management of patients with COVID-19 in the MICU.
COVID-19 management practices devised for the medical intensive care unit are centered on 2 main goals: ensuring caregiver safety and providing the highest quality patient care through adherence to evidence-based best practices. Rapid, sweeping changes for successful management are based on creating an educational plat...
Journal Article
Wu, Chao Ping;Latifi, Mani;Mireles-Cabodevila, Eduardo
10.3949/ccjm.87a.ccc017
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Management of patients with COVID-19 in the MICU. [Abstract]: COVID-19 management practices devised for the medical intensive care unit are centered on 2 main goals: ensuring caregiver safety and providing the highest quality patient care through adherence to evidence-based best practices. Rapid, sweeping chan...
32,080,994
Zhonghua Kou Qiang Yi Xue Za Zhi
[Emergency management of prevention and control of the novel coronavirus infection in departments of stomatology].
Complying with overall requirements of the government and regulations on public health emergencies, as well as the clinical features of diagnosis and treatment of oral diseases, this article reviews previous guidelines and studies on the infection control in dental practices in China and foreign countries. The emergenc...
covid-19;emergency management;infection control;pneumonia, viral;stomatological practice
Journal Article;Review
Tang, H S;Yao, Z Q;Wang, W M
10.3760/cma.j.cn112144-20200205-00037
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Emergency management of prevention and control of the novel coronavirus infection in departments of stomatology]. [Abstract]: Complying with overall requirements of the government and regulations on public health emergencies, as well as the clinical features of diagnosis and treatment of oral diseases, this a...
32,292,814
One Health
The SARS-CoV-2 outbreak from a one health perspective.
The severe acute respiratory syndrome cornavirus (SARS-CoV-2) is a new human coronavirus candidate recently detected in China that is now reported in people on inhabited continents. The virus shares a high level of identity with some bat coronaviruses and is recognised as a potentially zoonotic virus. We are utilizing ...
animal;bats;covid-19;coronavirus;mers-cov;one health;outbreak;reservoir;sars-cov;sars-cov-2
Journal Article
Hemida, Maged Gomaa;Ba Abduallah, Mohammed M
10.1016/j.onehlt.2020.100127
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The SARS-CoV-2 outbreak from a one health perspective. [Abstract]: The severe acute respiratory syndrome cornavirus (SARS-CoV-2) is a new human coronavirus candidate recently detected in China that is now reported in people on inhabited continents. The virus shares a high level of identity with some bat corona...
32,466,199
Int J Environ Res Public Health
Prioritizing and Analyzing the Role of Climate and Urban Parameters in the Confirmed Cases of COVID-19 Based on Artificial Intelligence Applications.
Nowadays, an infectious disease outbreak is considered one of the most destructive effects in the sustainable development process. The outbreak of new coronavirus (COVID-19) as an infectious disease showed that it has undesirable social, environmental, and economic impacts, and leads to serious challenges and threats. ...
covid-19;de;pso;artificial intelligence;feature selection;sustainable development
Journal Article;Research Support, Non-U.S. Gov't
Shaffiee Haghshenas, Sina;Pirouz, Behrouz;Shaffiee Haghshenas, Sami;Pirouz, Behzad;Piro, Patrizia;Na, Kyoung-Sae;Cho, Seo-Eun;Geem, Zong Woo
10.3390/ijerph17103730
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Prioritizing and Analyzing the Role of Climate and Urban Parameters in the Confirmed Cases of COVID-19 Based on Artificial Intelligence Applications. [Abstract]: Nowadays, an infectious disease outbreak is considered one of the most destructive effects in the sustainable development process. The outbreak of ne...
33,027,775
J Radiol Prot
A comparison of COVID-19 and imaging radiation risk in clinical patient populations.
OBJECTIVE: The outbreak of coronavirus SARS-COV2 affected more than 180 countries necessitating fast and accurate diagnostic tools. Reverse transcriptase polymerase chain reaction (RT-PCR) has been identified as a gold standard test with Chest CT and Chest Radiography showing promising results as well. However, radiolo...
covid-19;x-ray computed tomography;x-ray radiography;mortality;radiation risk
Journal Article
Ria, Francesco;Fu, Wanyi;Chalian, Hamid;Abadi, Ehsan;Segars, Paul W;Fricks, Rafael;Khoshpouri, Pegah;Samei, Ehsan
10.1088/1361-6498/abbf3b
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: A comparison of COVID-19 and imaging radiation risk in clinical patient populations. [Abstract]: OBJECTIVE: The outbreak of coronavirus SARS-COV2 affected more than 180 countries necessitating fast and accurate diagnostic tools. Reverse transcriptase polymerase chain reaction (RT-PCR) has been identified as a ...
32,928,086
Comb Chem High Throughput Screen
In silico modeling of small molecule carboxamides as inhibitors of SARS-CoV 3CL protease: An approach towards combating COVID-19.
BACKGROUND: The quantitative structure-activity relationship (QSAR) approach is most widely used for prediction of biological activity of potential medicinal compounds. A QSAR model is developed by correlating the information obtained from chemical structures (numerical descriptors/independent variables) with the exper...
3clpro enzyme;covid-19;design;qsar;carboxamides
Journal Article
Khan, Pathan Mohsin;Kumar, Vinay;Roy, Kunal
10.2174/1386207323666200914094712
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: In silico modeling of small molecule carboxamides as inhibitors of SARS-CoV 3CL protease: An approach towards combating COVID-19. [Abstract]: BACKGROUND: The quantitative structure-activity relationship (QSAR) approach is most widely used for prediction of biological activity of potential medicinal compounds. ...
32,471,812
Cleve Clin J Med
The role of palliative care in COVID-19.
In light of the COVID-19 pandemic, many healthcare systems are experiencing an increased demand for palliative care (PC). To meet this challenge, the PC team at Cleveland Clinic designed an enterprise-wide response plan organized around 4 domains: staff (educational resources and tools), stuff (medications and supplies...
Journal Article
Sese, Denise;Makhoul, Ahed;Hoeksema, Laura;Shoemaker, Laura
10.3949/ccjm.87a.ccc036
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The role of palliative care in COVID-19. [Abstract]: In light of the COVID-19 pandemic, many healthcare systems are experiencing an increased demand for palliative care (PC). To meet this challenge, the PC team at Cleveland Clinic designed an enterprise-wide response plan organized around 4 domains: staff (edu...
32,267,987
Rev Med Virol
Immune responses and pathogenesis of SARS-CoV-2 during an outbreak in Iran: Comparison with SARS and MERS.
The beginning of 2020 has seen the emergence of COVID-19, an outbreak caused by a novel coronavirus, SARS-CoV-2, an important pathogen for humans. There is an urgent need to better understand this new virus and to develop ways to control its spread. In Iran, the first case of the COVID-19 was reported after spread from...
2019-ncov disease;b cell;covid-19;sars-cov-2;t cell;coronavirus;immunity
Journal Article;Research Support, Non-U.S. Gov't;Review
Rokni, Mohsen;Ghasemi, Vida;Tavakoli, Zahra
10.1002/rmv.2107
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Immune responses and pathogenesis of SARS-CoV-2 during an outbreak in Iran: Comparison with SARS and MERS. [Abstract]: The beginning of 2020 has seen the emergence of COVID-19, an outbreak caused by a novel coronavirus, SARS-CoV-2, an important pathogen for humans. There is an urgent need to better understand ...
32,705,889
Am J Hosp Palliat Care
Palliative Care During COVID-19: Data and Visits From Loved Ones.
OBJECTIVES: A vital component of the coronavirus response is care of the dying COVID-19 patient. We document the demographics, symptoms experienced, medications required, effectiveness observed, and challenges to high-quality holistic palliative care in 31 patients. This will aid colleagues in primary and secondary car...
covid-19;sars-cov-2;bereavement;family management;holistic care;palliative medicine;symptom management
Journal Article
Heath, Laura;Yates, Sharon;Carey, Matthew;Miller, Mary
10.1177/1049909120943577
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Palliative Care During COVID-19: Data and Visits From Loved Ones. [Abstract]: OBJECTIVES: A vital component of the coronavirus response is care of the dying COVID-19 patient. We document the demographics, symptoms experienced, medications required, effectiveness observed, and challenges to high-quality holisti...
32,908,746
Case Rep Obstet Gynecol
COVID-19 Barriers to Care for Pregnant Patients in Prolonged Isolation.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent responsible for coronavirus disease 2019 (COVID-19), continues to have a devastating impact on healthcare systems worldwide, and many questions remain unanswered. The effect of COVID-19 on the pregnant population is widely debated, and the unique r...
Case Reports
Burgoyne, Mary E;Elsamadicy, Emad A;Cojocaru, Liviu;Desai, Andrea
10.1155/2020/8847859
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: COVID-19 Barriers to Care for Pregnant Patients in Prolonged Isolation. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent responsible for coronavirus disease 2019 (COVID-19), continues to have a devastating impact on healthcare systems worldwide, and many questions remain unan...
32,745,502
Genomics
Probing antiviral drugs against SARS-CoV-2 through virus-drug association prediction based on the KATZ method.
It is urgent to find an effective antiviral drug against SARS-CoV-2. In this study, 96 virus-drug associations (VDAs) from 12 viruses including SARS-CoV-2 and similar viruses and 78 small molecules are selected. Complete genomic sequence similarity of viruses and chemical structure similarity of drugs are then computed...
antiviral drug;molecular docking;sars-cov-2;vda;vda-katz
Journal Article;Research Support, Non-U.S. Gov't
Zhou, Liqian;Wang, Juanjuan;Liu, Guangyi;Lu, Qingqing;Dong, Ruyi;Tian, Geng;Yang, Jialiang;Peng, Lihong
10.1016/j.ygeno.2020.07.044
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Probing antiviral drugs against SARS-CoV-2 through virus-drug association prediction based on the KATZ method. [Abstract]: It is urgent to find an effective antiviral drug against SARS-CoV-2. In this study, 96 virus-drug associations (VDAs) from 12 viruses including SARS-CoV-2 and similar viruses and 78 small ...
32,687,645
Br J Clin Pharmacol
Clinical outcomes and adverse events in patients hospitalised with COVID-19, treated with off-label hydroxychloroquine and azithromycin.
AIMS: To assess clinical outcomes and adverse drug events in patients hospitalised with COVID-19 treated with off-label hydroxychloroquine (HCQ) and azithromycin (Az). METHODS: We performed a retrospective analysis of hospitalised patients who had a positive polymerase chain reaction test for SARS-CoV-2 and received HC...
covid-19;adverse drug events;azithromycin;clinical pharmacy;hydroxychloroquine;medication safety
Journal Article
Kelly, Mary;O'Connor, Roisin;Townsend, Liam;Coghlan, Miriam;Relihan, Eileen;Moriarty, Miriam;Carr, Bernard;Melanophy, Gail;Doyle, Caitriona;Bannan, Ciaran;O'Riordan, Ruth;Merry, Concepta;Clarke, Susie;Bergin, Colm
10.1111/bcp.14482
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Clinical outcomes and adverse events in patients hospitalised with COVID-19, treated with off-label hydroxychloroquine and azithromycin. [Abstract]: AIMS: To assess clinical outcomes and adverse drug events in patients hospitalised with COVID-19 treated with off-label hydroxychloroquine (HCQ) and azithromycin ...
32,641,681
Cell Death Dis
Is hydroxychloroquine beneficial for COVID-19 patients?
The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in December 2019. As similar cases rapidly emerged around the world(1-3), the World Health Organization (WHO) declared a public health emergency of international concern on Janua...
Journal Article;Review
Li, Xing;Wang, Ying;Agostinis, Patrizia;Rabson, Arnold;Melino, Gerry;Carafoli, Ernesto;Shi, Yufang;Sun, Erwei
10.1038/s41419-020-2721-8
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Is hydroxychloroquine beneficial for COVID-19 patients? [Abstract]: The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in December 2019. As similar cases rapidly emerged around the world(1-3), the World Health Organizati...
32,780,229
Eur J Clin Pharmacol
Safety of hydroxychloroquine in COVID-19 and other diseases: a systematic review and meta-analysis of 53 randomized trials.
INTRODUCTION: Many concerns still exist regarding the safety of hydroxychloroquine (HCQ) in the treatment of Coronavirus Disease 2019 (COVID-19). OBJECTIVES: The purpose of this study was to evaluate the safety of HCQ in the treatment of COVID-19 and other diseases by performing a systematic review and meta-analysis. M...
covid-19;hydroxychloroquine;randomized controlled trial;safety;systematic review
Journal Article;Meta-Analysis;Systematic Review
Chen, Can;Pan, Kunming;Wu, Bingjie;Li, Xiaoye;Chen, Zhangzhang;Xu, Qing;Li, Xiaoyu;Lv, Qianzhou
10.1007/s00228-020-02962-5
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Safety of hydroxychloroquine in COVID-19 and other diseases: a systematic review and meta-analysis of 53 randomized trials. [Abstract]: INTRODUCTION: Many concerns still exist regarding the safety of hydroxychloroquine (HCQ) in the treatment of Coronavirus Disease 2019 (COVID-19). OBJECTIVES: The purpose of th...
32,839,740
Am J Ophthalmol Case Rep
An adult with COVID-19 kawasaki-like syndrome and ocular manifestations.
Purpose: The severe acute respiratory syndrome coronavirus-2 and its associated infection known as COVID-19 have resulted in a global pandemic. Ocular manifestations of COVID-19 are nonspecific and include hyperemia, chemosis, epiphora, secretions, and eyelid edema. There is a paucity in the literature regarding COVID-...
covid-19;conjunctivitis;kawasaki disease;ocular manifestations of kawasaki disease
Case Reports
Lidder, Alcina K;Pandit, Saagar A;Lazzaro, Douglas R
10.1016/j.ajoc.2020.100875
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: An adult with COVID-19 kawasaki-like syndrome and ocular manifestations. [Abstract]: Purpose: The severe acute respiratory syndrome coronavirus-2 and its associated infection known as COVID-19 have resulted in a global pandemic. Ocular manifestations of COVID-19 are nonspecific and include hyperemia, chemosis,...
32,884,452
Biol Proced Online
Potential Diagnostic Systems for Coronavirus Detection: a Critical Review.
Abstract: Currently there are no effective anti-viral drugs for SARS-CoV-2, so the primary line of defense is to detect infected cases as soon as possible. The high rate of contagion for this virus and the highly nonspecific symptoms of the disease (Coronovirus disease 2019, (Covid-19)) that it causes, such as respirat...
biosensor;detection;immunoassay;nano-materials;rt-pcr;sars-cov-2
Journal Article;Review
Ekrami, Elena;Pouresmaieli, Mahdi;Barati, Fatemeh;Asghari, Sahar;Ziarani, Farzad Ramezani;Shariati, Parvin;Mamoudifard, Matin
10.1186/s12575-020-00134-4
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Potential Diagnostic Systems for Coronavirus Detection: a Critical Review. [Abstract]: Abstract: Currently there are no effective anti-viral drugs for SARS-CoV-2, so the primary line of defense is to detect infected cases as soon as possible. The high rate of contagion for this virus and the highly nonspecific...
33,064,451
Anal Chem
Comprehensive Analysis of the Glycan Complement of SARS-CoV-2 Spike Proteins Using Signature Ions-Triggered Electron-Transfer/Higher-Energy Collisional Dissociation (EThcD) Mass Spectrometry.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to a global pandemic of coronavirus disease 2019 (COVID-19). The spike protein expressed on the surface of this virus is highly glycosylated and plays an essential role during the process of infection. We conducted a comprehensive mass spectrometric a...
Journal Article
Wang, Dongxia;Baudys, Jakub;Bundy, Jonathan L;Solano, Maria;Keppel, Theodore;Barr, John R
10.1021/acs.analchem.0c03301
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Comprehensive Analysis of the Glycan Complement of SARS-CoV-2 Spike Proteins Using Signature Ions-Triggered Electron-Transfer/Higher-Energy Collisional Dissociation (EThcD) Mass Spectrometry. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to a global pandemic of coronavirus di...
32,710,059
Br Dent J
Relevance and paucity of evidence: a dental perspective on personal protective equipment during the COVID-19 pandemic.
The global COVID-19 pandemic, caused by the SARS-CoV-2 virus, has highlighted the importance of personal protective equipment (PPE) for health and social care personnel. This is a really important issue for dentistry, where we place great emphasis on infection control and universal precautions, given the nature of care...
Journal Article
Gallagher, Jennifer E;Johnson, Ilona;Verbeek, Jos H;Clarkson, Janet E;Innes, Nicola
10.1038/s41415-020-1843-9
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Relevance and paucity of evidence: a dental perspective on personal protective equipment during the COVID-19 pandemic. [Abstract]: The global COVID-19 pandemic, caused by the SARS-CoV-2 virus, has highlighted the importance of personal protective equipment (PPE) for health and social care personnel. This is a ...
32,354,651
Rev Neurol (Paris)
Guidance for the care of neuromuscular patients during the COVID-19 pandemic outbreak from the French Rare Health Care for Neuromuscular Diseases Network.
In France, the epidemic phase of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began in February 2020 and resulted in the implementation of emergency measures and a degradation in the organization of neuromuscular reference centers. In this special context, the French Rare Health Care ...
covid-19;guidelines;management;neuromuscular;treatment
Practice Guideline
Sole, G;Salort-Campana, E;Pereon, Y;Stojkovic, T;Wahbi, K;Cintas, P;Adams, D;Laforet, P;Tiffreau, V;Desguerre, I;Pisella, L I;Molon, A;Attarian, S
10.1016/j.neurol.2020.04.004
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Guidance for the care of neuromuscular patients during the COVID-19 pandemic outbreak from the French Rare Health Care for Neuromuscular Diseases Network. [Abstract]: In France, the epidemic phase of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began in February 2020 and resu...
32,586,724
Eur J Cancer
SARS-CoV-2 infection in cancer patients undergoing active treatment: analysis of clinical features and predictive factors for severe respiratory failure and death.
AIM: Previous studies have suggested a more frequent and severe course of novel coronavirus SARS-CoV-2 infection in cancer patients undergoing active oncologic treatment. Our aim was to describe the characteristics of the disease in this population and to determine predictive factors for poor outcome in terms of severe...
2019 novel coronavirus infection;adult;covid-19 virus disease;cancer;mortality;predictive factors;respiratory distress syndrome;treatment
Comparative Study;Journal Article
Yarza, Ramon;Bover, Mateo;Paredes, Diana;Lopez-Lopez, Flora;Jara-Casas, Diego;Castelo-Loureiro, Alicia;Baena, Javier;Mazarico, Jose Maria;Folgueira, Maria Dolores;Melendez-Carmona, Maria Angeles;Reyes, Alhena;Lumbreras, Carlos;Paz-Ares, Luis;Diaz-Pedroche, Carmen;Gomez-Martin, Carlos
10.1016/j.ejca.2020.06.001
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: SARS-CoV-2 infection in cancer patients undergoing active treatment: analysis of clinical features and predictive factors for severe respiratory failure and death. [Abstract]: AIM: Previous studies have suggested a more frequent and severe course of novel coronavirus SARS-CoV-2 infection in cancer patients und...
32,705,718
Clin Exp Dermatol
Irritant contact dermatitis in healthcare workers as a result of the COVID-19 pandemic: a cross-sectional study.
COVID-19 healthcare workers (HCWs) require frequent handwashing and use of personal protective equipment (PPE) to prevent infection. However, evidence is emerging that these practices are causing adverse effects on their skin integrity. A single-centre, cross-sectional study of HCWs from an Irish hospital was undertake...
Journal Article
Kiely, L F;Moloney, E;O'Sullivan, G;Eustace, J A;Gallagher, J;Bourke, J F
10.1111/ced.14397
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Irritant contact dermatitis in healthcare workers as a result of the COVID-19 pandemic: a cross-sectional study. [Abstract]: COVID-19 healthcare workers (HCWs) require frequent handwashing and use of personal protective equipment (PPE) to prevent infection. However, evidence is emerging that these practices ar...
32,544,242
Clin Infect Dis
Crisis Communication and Public Perception of COVID-19 Risk in the Era of Social Media.
A number of important principles in effective risk communication established in the late 20th century can provide important scientific insight into patient response to the risks posed by COVID-19 [1-3]. Early risk communication scholars studied public perceptions of risk in response to environmental disasters, or infec...
covid-19;risk communication;social media
Journal Article
Malecki, Kristen;Keating, Julie A;Safdar, Nasia
10.1093/cid/ciaa758
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Crisis Communication and Public Perception of COVID-19 Risk in the Era of Social Media. [Abstract]: A number of important principles in effective risk communication established in the late 20th century can provide important scientific insight into patient response to the risks posed by COVID-19 [1-3]. Early ri...
32,319,792
AJR Am J Roentgenol
Unexpected Findings of Coronavirus Disease (COVID-19) at the Lung Bases on Abdominopelvic CT.
OBJECTIVE. The purpose of this study is to report unanticipated lung base findings on abdominal CT in 23 patients concerning for coronavirus disease (COVID-19). In these patients, who were not previously suspected of having COVID-19, abdominal pain was the most common indication for CT (n = 19), and 11 patients had no ...
covid-19;sars-cov-2;abdominal ct;coronavirus;severe acute respiratory syndrome coronavirus 2
Journal Article
Dane, Bari;Brusca-Augello, Geraldine;Kim, Danny;Katz, Douglas S
10.2214/AJR.20.23240
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Unexpected Findings of Coronavirus Disease (COVID-19) at the Lung Bases on Abdominopelvic CT. [Abstract]: OBJECTIVE. The purpose of this study is to report unanticipated lung base findings on abdominal CT in 23 patients concerning for coronavirus disease (COVID-19). In these patients, who were not previously s...
32,348,405
Epidemiol Serv Saude
How Brazil can hold back COVID-19.
This article presents the strategies and actions adopted by the Brazilian Ministry of Health to hold back COVID-19. The response to the disease was immediate and occurred prior to the first case being detected in Brazil. Provision of information and communication to the population and the press was adopted as a fundame...
Journal Article
Oliveira, Wanderson Kleber de;Duarte, Elisete;Franca, Giovanny Vinicius Araujo de;Garcia, Leila Posenato
10.5123/s1679-49742020000200023
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: How Brazil can hold back COVID-19. [Abstract]: This article presents the strategies and actions adopted by the Brazilian Ministry of Health to hold back COVID-19. The response to the disease was immediate and occurred prior to the first case being detected in Brazil. Provision of information and communication ...
32,938,769
J Virol
The Enzymatic Activity of the nsp14 Exoribonuclease Is Critical for Replication of MERS-CoV and SARS-CoV-2.
Coronaviruses (CoVs) stand out for their large RNA genome and complex RNA-synthesizing machinery comprising 16 nonstructural proteins (nsps). The bifunctional nsp14 contains 3'-to-5' exoribonuclease (ExoN) and guanine-N7-methyltransferase (N7-MTase) domains. While the latter presumably supports mRNA capping, ExoN is th...
rna synthesis;guanine-n7-methyltransferase;nidovirus;nonstructural protein;proofreading;replicase;reverse genetics
Journal Article;Research Support, Non-U.S. Gov't
Ogando, Natacha S;Zevenhoven-Dobbe, Jessika C;van der Meer, Yvonne;Bredenbeek, Peter J;Posthuma, Clara C;Snijder, Eric J
10.1128/JVI.01246-20
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: The Enzymatic Activity of the nsp14 Exoribonuclease Is Critical for Replication of MERS-CoV and SARS-CoV-2. [Abstract]: Coronaviruses (CoVs) stand out for their large RNA genome and complex RNA-synthesizing machinery comprising 16 nonstructural proteins (nsps). The bifunctional nsp14 contains 3'-to-5' exoribon...
32,753,985
Risk Manag Healthc Policy
Administrative Mechanism of Joint Participation and Cooperation in the Early Stages of the COVID-19 Outbreak in Wuhan.
Introduction: From December 2019 to January 2020, a novel coronavirus disease (officially COVID-19) was reported in Wuhan and continued to spread all China. This study describes the administrative mechanism of joint participation and cooperation during the early stages of the COVID-19 outbreak in Wuhan and the rest of ...
coronavirus disease 2019;joint administration;policy participation;public health emergency
Journal Article
Yan, Jingjing;Zhao, Dahai
10.2147/RMHP.S251389
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Administrative Mechanism of Joint Participation and Cooperation in the Early Stages of the COVID-19 Outbreak in Wuhan. [Abstract]: Introduction: From December 2019 to January 2020, a novel coronavirus disease (officially COVID-19) was reported in Wuhan and continued to spread all China. This study describes th...
32,801,132
J Cell Sci
Science during lockdown - from virtual seminars to sustainable online communities.
The COVID-19 pandemic has disrupted traditional modes of scientific communication. In-person conferences and seminars have been cancelled and most scientists around the world have been confined to their homes. Although challenging, this situation has presented an opportunity to adopt new ways to communicate science and...
Journal Article;Research Support, Non-U.S. Gov't;Review
Bottanelli, Francesca;Cadot, Bruno;Campelo, Felix;Curran, Scott;Davidson, Patricia M;Dey, Gautam;Raote, Ishier;Straube, Anne;Swaffer, Matthew P
10.1242/jcs.249607
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Science during lockdown - from virtual seminars to sustainable online communities. [Abstract]: The COVID-19 pandemic has disrupted traditional modes of scientific communication. In-person conferences and seminars have been cancelled and most scientists around the world have been confined to their homes. Althou...
32,695,804
Stem Cell Investig
Cellular Therapy: Shafts of Light Emerging for COVID-19.
The COVID-19 pandemic has presented with debilitating respiratory consequences especially more pronounced in high risk individuals. Individuals with underlying systemic diseases are more prone and vulnerable to suffer severe consequences of SARS-CoV-2 infectivity. The pathophysiological changes identified cytokine stor...
covid-19;sars-cov-2;cellular therapy;mesenchymal stem cells (mscs);natural killer (nk) cells;platelet lysate
Journal Article;Review
Jeyaraman, Madhan;Ranjan, Rajni;Kumar, Rakesh;Arora, Arunabh;Chaudhary, Dushyant;Ajay, Satish Shringeri;Jain, Rashmi
10.21037/sci-2020-022
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Cellular Therapy: Shafts of Light Emerging for COVID-19. [Abstract]: The COVID-19 pandemic has presented with debilitating respiratory consequences especially more pronounced in high risk individuals. Individuals with underlying systemic diseases are more prone and vulnerable to suffer severe consequences of S...
32,732,016
Enferm Clin
Recommendations for the management of the patient with chronic renal disease with SARS-CoV-2.
The SARS-CoV-2 pandemic, which affects the entire population in general, poses a special risk for patients with chronic kidney disease because of their immunosuppression status, advanced age and the coexistence of significant comorbidity. Renal patients undergoing hemodialysis run the risk not only of suffering but als...
covid-19;clinical protocols;enfermedad renal;hemodialysis, kidney transplantation;hemodialisis;kidney diseases;protocolos clinicos;sars-cov-2;trasplante renal
Journal Article
Gomez-Beltran, Piedras Albas;Dominguez Carranza, Estela;Medero Rubio, Francisca;Perez Marquez, Manuela
10.1016/j.enfcli.2020.05.017
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Recommendations for the management of the patient with chronic renal disease with SARS-CoV-2. [Abstract]: The SARS-CoV-2 pandemic, which affects the entire population in general, poses a special risk for patients with chronic kidney disease because of their immunosuppression status, advanced age and the coexis...
32,552,412
Telemed J E Health
Cardiac Rehabilitation During COVID-19 Pandemic: Highlighting the Value of Home-Based Programs.
Cardiac rehabilitation (CR) is a class I treatment for cardiovascular disease, however, underutilization of these services remains. Home-based CR (HBCR) models have been implemented as a potential solution to addressing access barriers to CR services. Home-based models have been shown to be effective, however, there co...
home-based cardiac rehabilitation;prevention;telehealth
Journal Article;Research Support, U.S. Gov't, Non-P.H.S.
Drwal, Kariann R;Forman, Daniel E;Wakefield, Bonnie J;El Accaoui, Ramzi N
10.1089/tmj.2020.0213
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Cardiac Rehabilitation During COVID-19 Pandemic: Highlighting the Value of Home-Based Programs. [Abstract]: Cardiac rehabilitation (CR) is a class I treatment for cardiovascular disease, however, underutilization of these services remains. Home-based CR (HBCR) models have been implemented as a potential soluti...
33,067,472
Nat Commun
Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19.
SARS-CoV-2 is the novel coronavirus responsible for the current COVID-19 pandemic. Severe complications are observed only in a small proportion of infected patients but the cellular mechanisms underlying this progression are still unknown. Comprehensive flow cytometry of whole blood samples from 54 COVID-19 patients re...
Journal Article;Research Support, Non-U.S. Gov't
Carissimo, Guillaume;Xu, Weili;Kwok, Immanuel;Abdad, Mohammad Yazid;Chan, Yi-Hao;Fong, Siew-Wai;Puan, Kia Joo;Lee, Cheryl Yi-Pin;Yeo, Nicholas Kim-Wah;Amrun, Siti Naqiah;Chee, Rhonda Sin-Ling;How, Wilson;Chan, Stephrene;Fan, Bingwen Eugene;Andiappan, Anand Kumar;Lee, Bernett;Rotzschke, Olaf;Young, Barnaby Edward;Leo, Y...
10.1038/s41467-020-19080-6
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19. [Abstract]: SARS-CoV-2 is the novel coronavirus responsible for the current COVID-19 pandemic. Severe complications are observed only in a small proportion of infected patients but the cellula...
32,670,066
Front Pharmacol
Pharmacotherapics Advice in Guidelines for COVID-19.
Since December 2019 to May 2020, coronavirus disease 2019 (COVID-19) has infected over 6 million people worldwide. Due to its sudden and rapid outbreak, effective treatment for COVID-19 is scarce. Based on national clinical trials of novel treatments, China, Italy, Germany, and other countries and organizations have pu...
covid-19;sars-cov-2;guideline;pharmacotherapy;pneumonia
Journal Article;Review
Chen, Zhang-Ren;Zhou, Ying;Liu, Jin;Peng, Hong-Wei;Zhou, Jian;Zhong, Hai-Li;Liu, Li-Li;Lai, Ming-Fang;Wei, Xiao-Hua;Wen, Jin-Hua
10.3389/fphar.2020.00950
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Pharmacotherapics Advice in Guidelines for COVID-19. [Abstract]: Since December 2019 to May 2020, coronavirus disease 2019 (COVID-19) has infected over 6 million people worldwide. Due to its sudden and rapid outbreak, effective treatment for COVID-19 is scarce. Based on national clinical trials of novel treatm...
32,980,805
Biosens Bioelectron
Metal-organic frameworks for virus detection.
Virus severely endangers human life and health, and the detection of viruses is essential for the prevention and treatment of associated diseases. Metal-organic framework (MOF), a novel hybrid porous material which is bridged by the metal clusters and organic linkers, has become a promising biosensor platform for virus...
immunological detection;metal-organic framework;nucleic acid;virus detection
Journal Article;Review
Wang, Ying;Hu, Yaqin;He, Qunye;Yan, Jianhua;Xiong, Hongjie;Wen, Nachuan;Cai, Shundong;Peng, Dongming;Liu, Yanfei;Liu, Zhenbao
10.1016/j.bios.2020.112604
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Metal-organic frameworks for virus detection. [Abstract]: Virus severely endangers human life and health, and the detection of viruses is essential for the prevention and treatment of associated diseases. Metal-organic framework (MOF), a novel hybrid porous material which is bridged by the metal clusters and o...
32,860,259
Ann N Y Acad Sci
Transmission of SARS-CoV-2 through breast milk and breastfeeding: a living systematic review.
The pandemic of coronavirus disease 2019 (COVID-19) is caused by infection with a novel coronavirus strain, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). At present, there is limited information on potential transmission of the infection from mother to child, particularly through breast milk and bre...
2019 ncov;covid-19;sars-cov-2;breast milk;breastfeeding;mother-to-child transmission;novel coronavirus;perinatal transmission;severe acute respiratory syndrome;vertical transmission
Journal Article;Research Support, Non-U.S. Gov't;Systematic Review
Centeno-Tablante, Elizabeth;Medina-Rivera, Melisa;Finkelstein, Julia L;Rayco-Solon, Pura;Garcia-Casal, Maria Nieves;Rogers, Lisa;Ghezzi-Kopel, Kate;Ridwan, Pratiwi;Pena-Rosas, Juan Pablo;Mehta, Saurabh
10.1111/nyas.14477
[ 0, 0, 0, 0, 1, 0, 0 ]
[Title]: Transmission of SARS-CoV-2 through breast milk and breastfeeding: a living systematic review. [Abstract]: The pandemic of coronavirus disease 2019 (COVID-19) is caused by infection with a novel coronavirus strain, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). At present, there is limited in...
32,673,122
Expert Rev Anti Infect Ther
Loss of smell and taste: a new marker of COVID-19? Tracking reduced sense of smell during the coronavirus pandemic using search trends.
OBJECTIVES: It has been demonstrated that reduction in smell and/or taste is the most predictive symptom in SARS-CoV-2/Covid-19 infection. We used Google Trends to analyze regional searches relating to loss of smell and taste across Italy, Spain, France, Brazil, and the United States of America and determined the assoc...
covid-19;smell;aguesia;anosmia;olfaction disorders;search engine;taste
Journal Article
Cherry, George;Rocke, John;Chu, Michael;Liu, Jacklyn;Lechner, Matt;Lund, Valerie J;Kumar, B Nirmal
10.1080/14787210.2020.1792289
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Loss of smell and taste: a new marker of COVID-19? Tracking reduced sense of smell during the coronavirus pandemic using search trends. [Abstract]: OBJECTIVES: It has been demonstrated that reduction in smell and/or taste is the most predictive symptom in SARS-CoV-2/Covid-19 infection. We used Google Trends to...
32,651,936
Front Med
The role played by traditional Chinese medicine in preventing and treating COVID-19 in China.
Traditional Chinese medicine (TCM), an ancient system of alternative medicine, played an active role in the prevention and control of COVID-19 in China. It improved the clinical symptoms of patients, reduced the mortality rate, improved the recovery rate, and effectively relieved the operating pressure on the national ...
covid-19;wuchang pattern;convalescent patients;mobile cabin hospital;three formulae and three medicines;traditional chinese medicine
Journal Article
Li, Qingwei;Wang, Han;Li, Xiuyang;Zheng, Yujiao;Wei, Yu;Zhang, Pei;Ding, Qiyou;Lin, Jiaran;Tang, Shuang;Zhao, Yikun;Zhao, Linhua;Tong, Xiaolin
10.1007/s11684-020-0801-x
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: The role played by traditional Chinese medicine in preventing and treating COVID-19 in China. [Abstract]: Traditional Chinese medicine (TCM), an ancient system of alternative medicine, played an active role in the prevention and control of COVID-19 in China. It improved the clinical symptoms of patients, reduc...
32,836,597
Comput Mech
The reproduction number of COVID-19 and its correlation with public health interventions.
Throughout the past six months, no number has dominated the public media more persistently than the reproduction number of COVID-19. This powerful but simple concept is widely used by the public media, scientists, and political decision makers to explain and justify political strategies to control the COVID-19 pandemic...
covid-19;epidemiology;machine learning;reproduction number;seir model
Journal Article
Linka, Kevin;Peirlinck, Mathias;Kuhl, Ellen
10.1007/s00466-020-01880-8
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: The reproduction number of COVID-19 and its correlation with public health interventions. [Abstract]: Throughout the past six months, no number has dominated the public media more persistently than the reproduction number of COVID-19. This powerful but simple concept is widely used by the public media, scienti...
33,076,238
Int J Environ Res Public Health
Assessing the Distribution of Elderly Requiring Care: A Case Study on the Residents in Barcelona and the Impact of COVID-19.
In this work, we establish a methodological framework to analyze the care demand for elderly citizens in any area with a large proportion of elderly population, and to find connections to the cumulative incidence of COVID-19. Thanks to this analysis, it is possible to detect deficiencies in the public elderly care syst...
covid-19;care system;data analytics;elderly population
Journal Article;Research Support, Non-U.S. Gov't
Arvelo, Enrique;de Armas, Jesica;Guillen, Monserrat
10.3390/ijerph17207486
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Assessing the Distribution of Elderly Requiring Care: A Case Study on the Residents in Barcelona and the Impact of COVID-19. [Abstract]: In this work, we establish a methodological framework to analyze the care demand for elderly citizens in any area with a large proportion of elderly population, and to find c...
32,560,382
J Funct Biomater
Monoclonal-Type Plastic Antibodies for COVID-19 Treatment: What Is the Idea?
In late December 2019, an outbreak due to a novel coronavirus, initially called 2019-nCoV, was reported in Wuhan, China [...].
Editorial
Puoci, Francesco
10.3390/jfb11020043
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Monoclonal-Type Plastic Antibodies for COVID-19 Treatment: What Is the Idea? [Abstract]: In late December 2019, an outbreak due to a novel coronavirus, initially called 2019-nCoV, was reported in Wuhan, China [...]. [Keywords]:
32,535,228
J Struct Biol
Structural analysis of the putative SARS-CoV-2 primase complex.
We report the crystal structure of the SARS-CoV-2 putative primase composed of the nsp7 and nsp8 proteins. We observed a dimer of dimers (2:2 nsp7-nsp8) in the crystallographic asymmetric unit. The structure revealed a fold with a helical core of the heterotetramer formed by both nsp7 and nsp8 that is flanked with two ...
crystal structure;primase;rna;sars-cov-2
Journal Article;Research Support, Non-U.S. Gov't
Konkolova, Eva;Klima, Martin;Nencka, Radim;Boura, Evzen
10.1016/j.jsb.2020.107548
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Structural analysis of the putative SARS-CoV-2 primase complex. [Abstract]: We report the crystal structure of the SARS-CoV-2 putative primase composed of the nsp7 and nsp8 proteins. We observed a dimer of dimers (2:2 nsp7-nsp8) in the crystallographic asymmetric unit. The structure revealed a fold with a heli...
32,568,730
J Med Internet Res
COVID-19 Pneumonia Diagnosis Using a Simple 2D Deep Learning Framework With a Single Chest CT Image: Model Development and Validation.
BACKGROUND: Coronavirus disease (COVID-19) has spread explosively worldwide since the beginning of 2020. According to a multinational consensus statement from the Fleischner Society, computed tomography (CT) is a relevant screening tool due to its higher sensitivity for detecting early pneumonic changes. However, physi...
covid-19;ct;artificial intelligence;chest ct;convolutional neural networks, transfer learning;deep learning;diagnosis;neural network;pneumonia;scan
Journal Article;Validation Study
Ko, Hoon;Chung, Heewon;Kang, Wu Seong;Kim, Kyung Won;Shin, Youngbin;Kang, Seung Ji;Lee, Jae Hoon;Kim, Young Jun;Kim, Nan Yeol;Jung, Hyunseok;Lee, Jinseok
10.2196/19569
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 Pneumonia Diagnosis Using a Simple 2D Deep Learning Framework With a Single Chest CT Image: Model Development and Validation. [Abstract]: BACKGROUND: Coronavirus disease (COVID-19) has spread explosively worldwide since the beginning of 2020. According to a multinational consensus statement from the F...
32,731,721
Wiad Lek
[Statutory obligations of a doctor in the field of prevention and control of infectious diseases].
The spread of infectious diseases has been and poses a serious threat to the health of the entire population. The world is currently struggling with a SARS-CoV-2 coronavirus infection pandemic. The problem also concerns Poland and results in new legal regulations being issued. The law defines instruments for preventing...
doctor;statute;epidemic;infectious disease;information;coercion;hospitalization
Journal Article
Paszkowska, Malgorzata
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Statutory obligations of a doctor in the field of prevention and control of infectious diseases]. [Abstract]: The spread of infectious diseases has been and poses a serious threat to the health of the entire population. The world is currently struggling with a SARS-CoV-2 coronavirus infection pandemic. The pr...
32,725,595
Infection
Cardiac manifestations of COVID-19 in Shenzhen, China.
PURPOSE: The coronavirus disease 2019 (COVID-19) outbreak has become a global public health concern; however, relatively few detailed reports of related cardiac injury are available. The aims of this study were to compare the clinical and echocardiographic characteristics of inpatients in the intensive-care unit (ICU) ...
covid-19;coronavirus;echocardiography;intensive-care unit;myocarditis
Journal Article
Zeng, Jia-Hui;Wu, Wei-Bo;Qu, Jiu-Xin;Wang, Yao;Dong, Chang-Feng;Luo, Yong-Fang;Zhou, Dan;Feng, Wen-Xia;Feng, Cheng
10.1007/s15010-020-01473-w
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Cardiac manifestations of COVID-19 in Shenzhen, China. [Abstract]: PURPOSE: The coronavirus disease 2019 (COVID-19) outbreak has become a global public health concern; however, relatively few detailed reports of related cardiac injury are available. The aims of this study were to compare the clinical and echoc...
32,824,573
Genes (Basel)
Whole Genome Sequencing of SARS-CoV-2: Adapting Illumina Protocols for Quick and Accurate Outbreak Investigation during a Pandemic.
The COVID-19 pandemic has spread very fast around the world. A few days after the first detected case in South Africa, an infection started in a large hospital outbreak in Durban, KwaZulu-Natal (KZN). Phylogenetic analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomes can be used to trace the ...
covid-19;illumina;sars-cov2;bioinformatics;protocols;sequencing
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Pillay, Sureshnee;Giandhari, Jennifer;Tegally, Houriiyah;Wilkinson, Eduan;Chimukangara, Benjamin;Lessells, Richard;Moosa, Yunus;Mattison, Stacey;Gazy, Inbal;Fish, Maryam;Singh, Lavanya;Khanyile, Khulekani Sedwell;San, James Emmanuel;Fonseca, Vagner;Giovanetti, Marta;Alcantara, Luiz Carlos Jr;de Oliveira, Tulio
10.3390/genes11080949
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Whole Genome Sequencing of SARS-CoV-2: Adapting Illumina Protocols for Quick and Accurate Outbreak Investigation during a Pandemic. [Abstract]: The COVID-19 pandemic has spread very fast around the world. A few days after the first detected case in South Africa, an infection started in a large hospital outbrea...
32,837,516
Eur Surg
General surgeons' attitudes towards COVID-19: A national survey during the SARS-CoV-2 virus outbreak.
Background: The COVID-19 global pandemic left the unprepared health care systems struggling to mount a measured response. This gave rise to important questions about surgeons' attitude towards surgical practice and the level of preparation at work. Methods: Cross-sectional web-based national survey distributed to gener...
healthcare workers anxiety;healthcare workers safety;personal protective equipment;sars-cov-2 virus;surgical practice
Journal Article
Rymarowicz, Justyna;Stefura, Tomasz;Major, Piotr;Szeliga, Jacek;Wallner, Grzegorz;Nowakowski, Michal;Pedziwiatr, Michal
10.1007/s10353-020-00649-w
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: General surgeons' attitudes towards COVID-19: A national survey during the SARS-CoV-2 virus outbreak. [Abstract]: Background: The COVID-19 global pandemic left the unprepared health care systems struggling to mount a measured response. This gave rise to important questions about surgeons' attitude towards surg...
32,441,332
Acta Obstet Gynecol Scand
Clinical course of coronavirus disease-2019 in pregnancy.
INTRODUCTION: The aim of this study is to report our clinical experience in the management of pregnant women infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the first 30 days of the coronavirus disease (COVID-19) pandemic. MATERIAL AND METHODS: We reviewed clinical data from the first ...
breastfeeding;coronavirus 2;coronavirus disease-2019;labor;newborn;pregnancy;severe acute respiratory syndrome;severe acute respiratory syndrome coronavirus 2;vertical transmission
Journal Article
Pereira, Augusto;Cruz-Melguizo, Sara;Adrien, Maria;Fuentes, Lucia;Marin, Eugenia;Perez-Medina, Tirso
10.1111/aogs.13921
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical course of coronavirus disease-2019 in pregnancy. [Abstract]: INTRODUCTION: The aim of this study is to report our clinical experience in the management of pregnant women infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the first 30 days of the coronavirus disease (COVI...
32,984,929
Intern Emerg Med
Cardiac injury and mortality in patients with Coronavirus disease 2019 (COVID-19): insights from a mediation analysis.
BACKGROUNDS: Patients at greatest risk of severe clinical conditions from coronavirus disease 2019 (COVID-19) and death are elderly and comorbid patients. Increased levels of cardiac troponins identify patients with poor outcome. The present study aimed to describe the clinical characteristics and outcomes of a cohort ...
covid-19;cardiac injury;cardiac troponin;coronavirus 2019
Journal Article
Cipriani, Alberto;Capone, Federico;Donato, Filippo;Molinari, Leonardo;Ceccato, Davide;Saller, Alois;Previato, Lorenzo;Pesavento, Raffaele;Sarais, Cristiano;Fioretto, Paola;Iliceto, Sabino;Gregori, Dario;Avogaro, Angelo;Vettor, Roberto
10.1007/s11739-020-02495-w
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Cardiac injury and mortality in patients with Coronavirus disease 2019 (COVID-19): insights from a mediation analysis. [Abstract]: BACKGROUNDS: Patients at greatest risk of severe clinical conditions from coronavirus disease 2019 (COVID-19) and death are elderly and comorbid patients. Increased levels of cardi...
32,905,156
Chaos Solitons Fractals
Fractional order mathematical modeling of COVID-19 transmission.
In this article, the mathematical model with different compartments for the transmission dynamics of coronavirus-19 disease (COVID-19) is presented under the fractional-order derivative. Some results regarding the existence of at least one solution through fixed point results are derived. Then for the concerned approxi...
approximate solutions;caputo's fractional derivative;corona virus covid-19;fractional euler's method
Journal Article
Ahmad, Shabir;Ullah, Aman;Al-Mdallal, Qasem M;Khan, Hasib;Shah, Kamal;Khan, Aziz
10.1016/j.chaos.2020.110256
[ 0, 0, 0, 0, 1, 0, 0 ]
[Title]: Fractional order mathematical modeling of COVID-19 transmission. [Abstract]: In this article, the mathematical model with different compartments for the transmission dynamics of coronavirus-19 disease (COVID-19) is presented under the fractional-order derivative. Some results regarding the existence of at leas...
32,229,705
Aging (Albany NY)
Geroprotective and senoremediative strategies to reduce the comorbidity, infection rates, severity, and lethality in gerophilic and gerolavic infections.
The recently identified SARS-CoV-2 betacoronavirus responsible for the COVID-19 pandemic has uncovered the age-associated vulnerability in the burden of disease and put aging research in the spotlight. The limited data available indicates that COVID-19 should be referred to as a gerolavic (from Greek, geros "old man" a...
covid-19;sars-cov-2;coronavirus;rapalog;sirolimus
Journal Article;Review
Zhavoronkov, Alex
10.18632/aging.102988
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Geroprotective and senoremediative strategies to reduce the comorbidity, infection rates, severity, and lethality in gerophilic and gerolavic infections. [Abstract]: The recently identified SARS-CoV-2 betacoronavirus responsible for the COVID-19 pandemic has uncovered the age-associated vulnerability in the bu...
32,836,914
J Clean Prod
Spatial-temporal potential exposure risk analytics and urban sustainability impacts related to COVID-19 mitigation: A perspective from car mobility behaviour.
Coronavirus disease-2019 (COVID-19) poses a significant threat to the population and urban sustainability worldwide. The surge mitigation is complicated and associates many factors, including the pandemic status, policy, socioeconomics and resident behaviours. Modelling and analytics with spatial-temporal big urban dat...
air-emission reduction;covid-19;car mobility behaviour;flexible lockdown strategy;risk mitigation;spatial-temporal analysis
Journal Article
Jiang, Peng;Fu, Xiuju;Fan, Yee Van;Klemes, Jiri Jaromir;Chen, Piao;Ma, Stefan;Zhang, Wanbing
10.1016/j.jclepro.2020.123673
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Spatial-temporal potential exposure risk analytics and urban sustainability impacts related to COVID-19 mitigation: A perspective from car mobility behaviour. [Abstract]: Coronavirus disease-2019 (COVID-19) poses a significant threat to the population and urban sustainability worldwide. The surge mitigation is...
32,631,626
Clin Radiol
Validation of the British Society of Thoracic Imaging guidelines for COVID-19 chest radiograph reporting.
AIM: To validate the British Society of Thoracic Imaging issued guidelines for the categorisation of chest radiographs for coronavirus disease 2019 (COVID-19) reporting regarding reproducibility amongst radiologists and diagnostic performance. MATERIALS AND METHODS: Chest radiographs from 50 patients with COVID-19, and...
Journal Article;Validation Study
Hare, S S;Tavare, A N;Dattani, V;Musaddaq, B;Beal, I;Cleverley, J;Cash, C;Lemoniati, E;Barnett, J
10.1016/j.crad.2020.06.005
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Validation of the British Society of Thoracic Imaging guidelines for COVID-19 chest radiograph reporting. [Abstract]: AIM: To validate the British Society of Thoracic Imaging issued guidelines for the categorisation of chest radiographs for coronavirus disease 2019 (COVID-19) reporting regarding reproducibilit...
32,712,607
Kidney Blood Press Res
Acute Kidney Injury in Patients with the Coronavirus Disease 2019: A Multicenter Study.
INTRODUCTION: Severe acute respiratory viral infections are frequency accompanied by multiple organ dysfunction, including acute kidney injury (AKI). In December 2019, the coronavirus disease 2019 (COVID-19) outbreak began in Wuhan, Hubei Province, China, and rapidly spread worldwide. While diffuse alveolar damage and ...
acute kidney injury;coronavirus disease 2019;extrapulmonary complications
Journal Article;Multicenter Study;Observational Study
Cui, Xiaoyang;Yu, Xin;Wu, Xiaojing;Huang, Linna;Tian, Ye;Huang, Xu;Zhang, Zeyu;Cheng, Zhenshun;Guo, Qiang;Zhang, Yi;Cai, Ying;Zhan, Qingyuan
10.1159/000509517
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Acute Kidney Injury in Patients with the Coronavirus Disease 2019: A Multicenter Study. [Abstract]: INTRODUCTION: Severe acute respiratory viral infections are frequency accompanied by multiple organ dysfunction, including acute kidney injury (AKI). In December 2019, the coronavirus disease 2019 (COVID-19) out...
32,467,244
J Neurointerv Surg
Delayed presentation of acute ischemic strokes during the COVID-19 crisis.
BACKGROUND: The COVID-19 pandemic has disrupted established care paths worldwide. Patient awareness of the pandemic and executive limitations imposed on public life have changed the perception of when to seek care for acute conditions in some cases. We sought to study whether there is a delay in presentation for acute ...
statistics;stroke
Journal Article;Multicenter Study
Schirmer, Clemens M;Ringer, Andrew J;Arthur, Adam S;Binning, Mandy J;Fox, W Christopher;James, Robert F;Levitt, Michael R;Tawk, Rabih G;Veznedaroglu, Erol;Walker, Melanie;Spiotta, Alejandro M
10.1136/neurintsurg-2020-016299
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Delayed presentation of acute ischemic strokes during the COVID-19 crisis. [Abstract]: BACKGROUND: The COVID-19 pandemic has disrupted established care paths worldwide. Patient awareness of the pandemic and executive limitations imposed on public life have changed the perception of when to seek care for acute ...
32,715,050
Data Brief
Data and debriefing observations on healthcare simulation to prepare for the COVID-19 pandemic.
We report on data and debriefing observations in the context of an immersive simulation conducted to (a) train clinicians and (b) test new protocols and kits, developed in table-top exercises without prior clinical experience to fit anticipated clinical encounters in the setting of the rapidly expanding COVID-19 pandem...
acute respiratory syndrome coronavirus;adult critical care;anesthesiology;crisis resource management;perioperative care;personal protective equipment;simulation;system integration
Journal Article
Andreae, M H;Dudak, A;Cherian, V;Dhar, P;Dalal, P G;Po, W;Pilipovic, M;Shah, B;Hazard, W;Rodgers, D L;Sinz, E H
10.1016/j.dib.2020.106028
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Data and debriefing observations on healthcare simulation to prepare for the COVID-19 pandemic. [Abstract]: We report on data and debriefing observations in the context of an immersive simulation conducted to (a) train clinicians and (b) test new protocols and kits, developed in table-top exercises without pri...
32,110,742
Infect Dis Model
Real-time forecasts of the COVID-19 epidemic in China from February 5th to February 24th, 2020.
The initial cluster of severe pneumonia cases that triggered the COVID-19 epidemic was identified in Wuhan, China in December 2019. While early cases of the disease were linked to a wet market, human-to-human transmission has driven the rapid spread of the virus throughout China. The Chinese government has implemented ...
covid-19;china;coronavirus;phenomenological models;real-time forecasts
Journal Article
Roosa, K;Lee, Y;Luo, R;Kirpich, A;Rothenberg, R;Hyman, J M;Yan, P;Chowell, G
10.1016/j.idm.2020.02.002
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Real-time forecasts of the COVID-19 epidemic in China from February 5th to February 24th, 2020. [Abstract]: The initial cluster of severe pneumonia cases that triggered the COVID-19 epidemic was identified in Wuhan, China in December 2019. While early cases of the disease were linked to a wet market, human-to-...
32,399,806
Stem Cell Rev Rep
Is COVID-19 a New Hematologic Disease?
SARS-CoV-2 viruses are positive single-stranded RNA viruses, whose infection can be asymptomatic or lead to the coronavirus disease 2019 (Covid-19). Covid-19 is a respiratory infection with a significant impact on the hematopoietic system and hemostasis leading to several cardiovascular complications. Hematologic conse...
coagulopathy;covid-19;cytokine;d-dimers;inflammation;lymphopenia;mesenchymal stem cells;sars-cov-2;stem cells;thrombosis
Journal Article;Research Support, Non-U.S. Gov't
Debuc, Benjamin;Smadja, David M
10.1007/s12015-020-09987-4
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Is COVID-19 a New Hematologic Disease? [Abstract]: SARS-CoV-2 viruses are positive single-stranded RNA viruses, whose infection can be asymptomatic or lead to the coronavirus disease 2019 (Covid-19). Covid-19 is a respiratory infection with a significant impact on the hematopoietic system and hemostasis leadin...
32,909,843
Expert Rev Clin Pharmacol
Remdesivir emergency approvals: a comparison of the U.S., Japanese, and EU systems.
INTRODUCTION: There were no formal regulatory approvals for antivirals for the COVID-19 pandemic as of June 2020. AREAS COVERED: We compare the first regulatory approvals for remdesivir, through emergency pathways available to three of the main regulators in the world, the U.S., Japan, and the EU. We look at the data s...
covid-19;regulatory;anti-viral;compassionate use;conditional marketing authorization;emergency use;marketing authorization
Comparative Study;Journal Article;Review
Saint-Raymond, A;Sato, J;Kishioka, Y;Teixeira, T;Hasslboeck, C;Kweder, S L
10.1080/17512433.2020.1821650
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Remdesivir emergency approvals: a comparison of the U.S., Japanese, and EU systems. [Abstract]: INTRODUCTION: There were no formal regulatory approvals for antivirals for the COVID-19 pandemic as of June 2020. AREAS COVERED: We compare the first regulatory approvals for remdesivir, through emergency pathways a...
32,584,326
Rev Invest Clin
CLINICAL AND EPIDEMIOLOGICAL CHARACTERISTICS OF PATIENTS DIAGNOSED WITH COVID-19 IN A TERTIARY CARE CENTER IN MEXICO CITY: A PROSPECTIVE COHORT STUDY.
Background: Regional information regarding the characteristics of patients with coronavirus disease (COVID)-19 is needed for a better understanding of the pandemic. Objective: The objective of the study to describe the clinical features of COVID-19 patients diagnosed in a tertiary-care center in Mexico City and to asse...
2019-novel coronavirus;cohort;coronavirus;coronavirus disease-2019;mexico;severe acute respiratory syndrome coronavirus 2
Journal Article
Ortiz-Brizuela, Edgar;Villanueva-Reza, Marco;Gonzalez-Lara, Maria F;Tamez-Torres, Karla M;Roman-Montes, Carla M;Diaz-Mejia, Bruno A;Perez-Garcia, Esteban;Olivas-Martinez, Antonio;Rajme-Lopez, Sandra;Martinez-Guerra, Bernardo A;de-Leon-Cividanes, Nereyda A;Fernandez-Garcia, Oscar A;Guerrero-Torres, Lorena;Torres-Gonzale...
10.24875/RIC.20000211
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: CLINICAL AND EPIDEMIOLOGICAL CHARACTERISTICS OF PATIENTS DIAGNOSED WITH COVID-19 IN A TERTIARY CARE CENTER IN MEXICO CITY: A PROSPECTIVE COHORT STUDY. [Abstract]: Background: Regional information regarding the characteristics of patients with coronavirus disease (COVID)-19 is needed for a better understanding ...
32,518,555
Chin Herb Med
Pay attention to situation of SARS-CoV-2 and TCM advantages in treatment of novel coronavirus infection.
Since the outbreak of the new coronavirus epidemic, novel coronavirus has infected nearly 100,000 people in more than 110 countries. How to face this new coronavirus epidemic outbreak is an important issue. Basic reproduction number (R0) is an important parameter in epidemiology; The basic reproduction number of an inf...
covid-19;sars-cov-2;tcm advantages;basic reproduction number;epidemiology dynamics;national healthcare system capacity;novel coronavirus infection
Journal Article;Review
Liu, Chang-Xiao
10.1016/j.chmed.2020.03.004
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Pay attention to situation of SARS-CoV-2 and TCM advantages in treatment of novel coronavirus infection. [Abstract]: Since the outbreak of the new coronavirus epidemic, novel coronavirus has infected nearly 100,000 people in more than 110 countries. How to face this new coronavirus epidemic outbreak is an impo...
33,028,491
Surgeon
Are there benefits to maintaining Covid-19 pandemic pathways for the long-term? A surgical assessment unit based study.
BACKGROUND: The Covid-19 pandemic has led to the introduction of conservative non-operative approaches to surgical management favouring community driven care. The aim of this study was to determine the effect of these pathways on patients attending a surgical assessment unit (SAU). METHOD: This was a retrospective obse...
covid-19;general surgery;pandemic;surgical assessment unit
Journal Article
Laskar, Naomi Simone;Hunt, Alexander;Karunaratne, Dilhara;Brooke-Ball, Hannah;Miller, Matthew T V
10.1016/j.surge.2020.08.015
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Are there benefits to maintaining Covid-19 pandemic pathways for the long-term? A surgical assessment unit based study. [Abstract]: BACKGROUND: The Covid-19 pandemic has led to the introduction of conservative non-operative approaches to surgical management favouring community driven care. The aim of this stud...
32,534,226
Biomed Pharmacother
Monoclonal antibody as a potential anti-COVID-19.
Coronavirus disease 2019 (COVID-19) is expanding rapidly, which made it as one of top priorities for scientists to develop novel treatment strategies. Researchers are racing to develop treatments based on antibodies to block and/or neutralize the coronavirus in affected patients. Initially, the genetic and structural s...
covid-19;monoclonal antibodies;sars-cov;treatment
Journal Article;Review
Jahanshahlu, Leila;Rezaei, Nima
10.1016/j.biopha.2020.110337
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Monoclonal antibody as a potential anti-COVID-19. [Abstract]: Coronavirus disease 2019 (COVID-19) is expanding rapidly, which made it as one of top priorities for scientists to develop novel treatment strategies. Researchers are racing to develop treatments based on antibodies to block and/or neutralize the co...
32,871,342
Eur J Med Chem
Azithromycin: The First Broad-spectrum Therapeutic.
The Strategic Plan for Biodefense Research by the U.S. Department of Health and Human Services demarcates the need for drugs which target multiple types of pathogens to prepare for infectious threats. Azithromycin is one such broad-spectrum therapeutic that is both included in the University of Oxford's RECOVERY and ex...
azithromycin;broad-spectrum therapeutic;covid-19
Journal Article;Review
Firth, Anton;Prathapan, Praveen
10.1016/j.ejmech.2020.112739
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Azithromycin: The First Broad-spectrum Therapeutic. [Abstract]: The Strategic Plan for Biodefense Research by the U.S. Department of Health and Human Services demarcates the need for drugs which target multiple types of pathogens to prepare for infectious threats. Azithromycin is one such broad-spectrum therap...
32,470,046
PLoS One
Pathogen reduction of SARS-CoV-2 virus in plasma and whole blood using riboflavin and UV light.
BACKGROUND: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has recently been identified as the causative agent for Coronavirus Disease 2019 (COVID-19). The ability of this agent to be transmitted by blood transfusion has not been documented, although viral RNA has been detected in serum. Exposure to treat...
Journal Article;Research Support, Non-U.S. Gov't
Ragan, Izabela;Hartson, Lindsay;Pidcoke, Heather;Bowen, Richard;Goodrich, Raymond
10.1371/journal.pone.0233947
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Pathogen reduction of SARS-CoV-2 virus in plasma and whole blood using riboflavin and UV light. [Abstract]: BACKGROUND: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has recently been identified as the causative agent for Coronavirus Disease 2019 (COVID-19). The ability of this agent to be trans...
33,034,353
Chem Senses
Surveying Chemosensory Dysfunction in COVID-19.
Soon after the outbreak of COVID-19, reports that smell and taste are disrupted by the illness drew the attention of chemosensory scientists and clinicians throughout the world. While other upper respiratory viruses are known to produce such disruptions, their occurrence with the deadly and highly infectious SARS-CoV-2...
covid-19;chemesthesis;human;olfaction;taste
Journal Article
Green, Barry G
10.1093/chemse/bjaa048
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Surveying Chemosensory Dysfunction in COVID-19. [Abstract]: Soon after the outbreak of COVID-19, reports that smell and taste are disrupted by the illness drew the attention of chemosensory scientists and clinicians throughout the world. While other upper respiratory viruses are known to produce such disruptio...
32,810,841
J Med Internet Res
Patient Satisfaction With Telemedicine During the COVID-19 Pandemic: Retrospective Cohort Study.
BACKGROUND: New York City was the international epicenter of the COVID-19 pandemic. Health care providers responded by rapidly transitioning from in-person to video consultations. Telemedicine (ie, video visits) is a potentially disruptive innovation; however, little is known about patient satisfaction with this emergi...
covid-19;disruptive technology;health care delivery;health care reform;health policy;health services research;medical informatics;medicine;pandemics;patient satisfaction;physicians;practice patterns;remote consultation;telemedicine
Journal Article;Observational Study
Ramaswamy, Ashwin;Yu, Miko;Drangsholt, Siri;Ng, Eric;Culligan, Patrick J;Schlegel, Peter N;Hu, Jim C
10.2196/20786
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Patient Satisfaction With Telemedicine During the COVID-19 Pandemic: Retrospective Cohort Study. [Abstract]: BACKGROUND: New York City was the international epicenter of the COVID-19 pandemic. Health care providers responded by rapidly transitioning from in-person to video consultations. Telemedicine (ie, vide...
32,829,044
Int J Infect Dis
Case studies of SARS-CoV-2 treated with favipiravir among patients in critical or severe condition.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak is rising globally. However, clinically effective antiviral treatments are not established. Favipiravir may prevent pneumonia and acute respiratory distress syndrome aggravation. We describe SARS-CoV-2-positive patients, two of whom were in a cri...
covid-19;sars-cov-2;acute respiratory distress syndrome;favipiravir;viral pneumonia
Case Reports
Takahashi, Hidenori;Iwasaki, Yoshinobu;Watanabe, Takayasu;Ichinose, Naoki;Okada, Yasusei;Oiwa, Akito;Kobayashi, Takehiro;Moriya, Mariko;Oda, Toshimi
10.1016/j.ijid.2020.08.047
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Case studies of SARS-CoV-2 treated with favipiravir among patients in critical or severe condition. [Abstract]: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak is rising globally. However, clinically effective antiviral treatments are not established. Favipiravir may prevent pneumonia...
32,841,167
Rom J Intern Med
Anticoagulant protein S in COVID-19: low activity, and associated with outcome.
INTRODUCTION: COVID-19 disease was associated with both thrombo-embolic events and in-situ thrombi formation in small vessels. Antiphospholipidic antibodies were found in some studies. AIM: Assessment of protein S activity in patients with COVID-19 as a cause this prothrombotic state, and of the association of protein ...
covid-19;neutrophilia;protein s;thrombophilia;thrombosis
Journal Article
Stoichitoiu, Laura Elena;Pinte, Larisa;Balea, Marius Ioan;Nedelcu, Valentin;Badea, Camelia;Baicus, Cristian
10.2478/rjim-2020-0024
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Anticoagulant protein S in COVID-19: low activity, and associated with outcome. [Abstract]: INTRODUCTION: COVID-19 disease was associated with both thrombo-embolic events and in-situ thrombi formation in small vessels. Antiphospholipidic antibodies were found in some studies. AIM: Assessment of protein S activ...
32,621,109
J Nephrol
Exposure to novel coronavirus in patients on renal replacement therapy during the exponential phase of COVID-19 pandemic: survey of the Italian Society of Nephrology.
BACKGROUND: Between February and April 2020, Italy experienced an overwhelming growth of the COVID-19 pandemic. Little is known, at the country level, where and how patients on renal replacement therapy (RRT) have been mostly affected. METHODS: Survey of the network of Nephrology centers using a simplified 17 items ele...
covid-19;hemodialysis;peritoneal dialysis;renal transplant;survey
Journal Article
Quintaliani, Giuseppe;Reboldi, Gianpaolo;Di Napoli, Anteo;Nordio, Maurizio;Limido, Aurelio;Aucella, Filippo;Messa, Piergiorgio;Brunori, Giuliano
10.1007/s40620-020-00794-1
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Exposure to novel coronavirus in patients on renal replacement therapy during the exponential phase of COVID-19 pandemic: survey of the Italian Society of Nephrology. [Abstract]: BACKGROUND: Between February and April 2020, Italy experienced an overwhelming growth of the COVID-19 pandemic. Little is known, at ...
32,683,439
Bioinformatics
Protein-sol pKa: prediction of electrostatic frustration, with application to coronaviruses.
MOTIVATION: Evolution couples differences in ambient pH to biological function through protonatable groups, in particular, those that switch from buried to exposed and alter protonation state in doing so. We present a tool focusing on structure-based discovery and display of these groups. RESULTS: Since prediction of b...
Journal Article;Research Support, Non-U.S. Gov't
Hebditch, Max;Warwicker, Jim
10.1093/bioinformatics/btaa646
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Protein-sol pKa: prediction of electrostatic frustration, with application to coronaviruses. [Abstract]: MOTIVATION: Evolution couples differences in ambient pH to biological function through protonatable groups, in particular, those that switch from buried to exposed and alter protonation state in doing so. W...
32,652,499
Int Immunopharmacol
Use of Machine Learning and Artificial Intelligence to predict SARS-CoV-2 infection from Full Blood Counts in a population.
Since December 2019 the novel coronavirus SARS-CoV-2 has been identified as the cause of the pandemic COVID-19. Early symptoms overlap with other common conditions such as common cold and Influenza, making early screening and diagnosis are crucial goals for health practitioners. The aim of the study was to use machine ...
artificial neural network (ann);full blood count;leukocytes;machine learning;monocytes;sars-cov-2;screening
Journal Article
Banerjee, Abhirup;Ray, Surajit;Vorselaars, Bart;Kitson, Joanne;Mamalakis, Michail;Weeks, Simonne;Baker, Mark;Mackenzie, Louise S
10.1016/j.intimp.2020.106705
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Use of Machine Learning and Artificial Intelligence to predict SARS-CoV-2 infection from Full Blood Counts in a population. [Abstract]: Since December 2019 the novel coronavirus SARS-CoV-2 has been identified as the cause of the pandemic COVID-19. Early symptoms overlap with other common conditions such as com...
32,599,867
Biology (Basel)
On a Coupled Time-Dependent SIR Models Fitting with New York and New-Jersey States COVID-19 Data.
This article describes a simple Susceptible Infected Recovered (SIR) model fitting with COVID-19 data for the month of March 2020 in New York (NY) state. The model is a classical SIR, but is non-autonomous; the rate of susceptible people becoming infected is adjusted over time in order to fit the available data. The de...
covid-19;network;new jersey;new york;sir models
Journal Article
Ambrosio, Benjamin;Aziz-Alaoui, M A
10.3390/biology9060135
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: On a Coupled Time-Dependent SIR Models Fitting with New York and New-Jersey States COVID-19 Data. [Abstract]: This article describes a simple Susceptible Infected Recovered (SIR) model fitting with COVID-19 data for the month of March 2020 in New York (NY) state. The model is a classical SIR, but is non-autono...
32,907,623
J Med Case Rep
Pericardial effusion and cardiac tamponade requiring pericardial window in an otherwise healthy 30-year-old patient with COVID-19: a case report.
BACKGROUND: This case report demonstrates pericardial effusion, acute pericarditis, and cardiac tamponade in an otherwise healthy woman who had a positive test result for coronavirus disease 2019. Few case reports have been documented on patients with this presentation, and it is important to share novel presentations ...
acute pericarditis;covid-19;cardiac tamponade;case report;pericardial effusion
Case Reports;Journal Article
Walker, Christina;Peyko, Vincent;Farrell, Charles;Awad-Spirtos, Jeanine;Adamo, Matthew;Scrocco, John
10.1186/s13256-020-02467-w
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Pericardial effusion and cardiac tamponade requiring pericardial window in an otherwise healthy 30-year-old patient with COVID-19: a case report. [Abstract]: BACKGROUND: This case report demonstrates pericardial effusion, acute pericarditis, and cardiac tamponade in an otherwise healthy woman who had a positiv...
32,550,953
Can Geriatr J
Age Alone is not Adequate to Determine Health-care Resource Allocation During the COVID-19 Pandemic.
Background: The Canadian Geriatrics Society (CGS) fosters the health and well-being of older Canadians and older adults worldwide. Although severe COVID-19 illness and significant mortality occur across the lifespan, the fatality rate increases with age, especially for people over 65 years of age. The dichotomization o...
covid-19;aged;frailty;health-care resources;mechanical ventilation
Journal Article
Montero-Odasso, Manuel;Hogan, David B;Lam, Robert;Madden, Kenneth;MacKnight, Christopher;Molnar, Frank;Rockwood, Kenneth
10.5770/cgj.23.452
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Age Alone is not Adequate to Determine Health-care Resource Allocation During the COVID-19 Pandemic. [Abstract]: Background: The Canadian Geriatrics Society (CGS) fosters the health and well-being of older Canadians and older adults worldwide. Although severe COVID-19 illness and significant mortality occur ac...
32,362,244
Int J Stroke
Management of acute ischemic stroke in patients with COVID-19 infection: Report of an international panel.
BACKGROUND AND PURPOSE: On 11 March 2020, World Health Organization (WHO) declared the COVID-19 infection a pandemic. The risk of ischemic stroke may be higher in patients with COVID-19 infection similar to those with other respiratory tract infections. We present a comprehensive set of practice implications in a singl...
covid-19;coronavirus;acute stroke;ischemic stroke;mechanical thrombectomy;thrombolysis
Consensus Development Conference;Journal Article
Qureshi, Adnan I;Abd-Allah, Foad;Al-Senani, Fahmi;Aytac, Emrah;Borhani-Haghighi, Afshin;Ciccone, Alfonso;Gomez, Camilo R;Gurkas, Erdem;Hsu, Chung Y;Jani, Vishal;Jiao, Liqun;Kobayashi, Adam;Lee, Jun;Liaqat, Jahanzeb;Mazighi, Mikael;Parthasarathy, Rajsrinivas;Steiner, Thorsten;Suri, M Fareed K;Toyoda, Kazunori;Ribo, Marc...
10.1177/1747493020923234
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Management of acute ischemic stroke in patients with COVID-19 infection: Report of an international panel. [Abstract]: BACKGROUND AND PURPOSE: On 11 March 2020, World Health Organization (WHO) declared the COVID-19 infection a pandemic. The risk of ischemic stroke may be higher in patients with COVID-19 infect...
32,357,575
Geriatrics (Basel)
COVID-19: A Geriatric Emergency.
The older Italian population is posing a challenge in the number of deaths for coronavirus disease 2019 (COVID-19). According to previous data from China, pre-existing health conditions dramatically increase the risk of dying from COVID-19. The presence of multiple diseases in older patients may be considered as a mark...
covid-19;aging;frailty;geriatrics;older
Editorial
Boccardi, Virginia;Ruggiero, Carmelinda;Mecocci, Patrizia
10.3390/geriatrics5020024
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19: A Geriatric Emergency. [Abstract]: The older Italian population is posing a challenge in the number of deaths for coronavirus disease 2019 (COVID-19). According to previous data from China, pre-existing health conditions dramatically increase the risk of dying from COVID-19. The presence of multiple ...
32,773,845
Indian J Anaesth
Indian Resuscitation Council (IRC) suggested guidelines for Comprehensive Cardiopulmonary Life Support (CCLS) for suspected or confirmed coronavirus disease (COVID-19) patient.
Management of the recent outbreak of the novel coronavirus disease (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) remains challenging. The challenges are not only limited to its preventive strategies, but also extend to curative treatment, and are amplified during the management of...
airway management;covid-19;sars-cov-2;breathing;cardiopulmonary resuscitation;chest compression
Journal Article
Singh, Baljit;Garg, Rakesh;Chakra Rao, S S C;Ahmed, Syed M;Divatia, J V;Ramakrishnan, T V;Mehdiratta, Lalit;Joshi, Muralidhar;Malhotra, Naveen;Bajwa, Sukhminder Jit Singh
10.4103/ija.IJA_481_20
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Indian Resuscitation Council (IRC) suggested guidelines for Comprehensive Cardiopulmonary Life Support (CCLS) for suspected or confirmed coronavirus disease (COVID-19) patient. [Abstract]: Management of the recent outbreak of the novel coronavirus disease (COVID-19) caused by the severe acute respiratory syndr...
32,416,785
Lancet
Use of renin-angiotensin-aldosterone system inhibitors and risk of COVID-19 requiring admission to hospital: a case-population study.
BACKGROUND: Concerns have been raised about the possibility that inhibitors of the renin-angiotensin-aldosterone system (RAAS) could predispose individuals to severe COVID-19; however, epidemiological evidence is lacking. We report the results of a case-population study done in Madrid, Spain, since the outbreak of COVI...
Journal Article;Research Support, Non-U.S. Gov't
de Abajo, Francisco J;Rodriguez-Martin, Sara;Lerma, Victoria;Mejia-Abril, Gina;Aguilar, Monica;Garcia-Luque, Amelia;Laredo, Leonor;Laosa, Olga;Centeno-Soto, Gustavo A;Angeles Galvez, Maria;Puerro, Miguel;Gonzalez-Rojano, Esperanza;Pedraza, Laura;de Pablo, Itziar;Abad-Santos, Francisco;Rodriguez-Manas, Leocadio;Gil, Mig...
10.1016/S0140-6736(20)31030-8
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Use of renin-angiotensin-aldosterone system inhibitors and risk of COVID-19 requiring admission to hospital: a case-population study. [Abstract]: BACKGROUND: Concerns have been raised about the possibility that inhibitors of the renin-angiotensin-aldosterone system (RAAS) could predispose individuals to severe...
32,512,362
Sci Total Environ
Assessing the relationship between surface levels of PM2.5 and PM10 particulate matter impact on COVID-19 in Milan, Italy.
The novel coronavirus disease (COVID-19) is a highly pathogenic, transmittable and invasive pneumococcal disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which emerged in December 2019 and January 2020 in Wuhan city, Hubei province, China and fast spread later on the middle of February 20...
air quality;coronavirus covid-19;meteorological parameters;noaa satellite data;particulate matter (pm2.5 and pm10)
Journal Article
Zoran, Maria A;Savastru, Roxana S;Savastru, Dan M;Tautan, Marina N
10.1016/j.scitotenv.2020.139825
[ 0, 0, 1, 1, 1, 0, 0 ]
[Title]: Assessing the relationship between surface levels of PM2.5 and PM10 particulate matter impact on COVID-19 in Milan, Italy. [Abstract]: The novel coronavirus disease (COVID-19) is a highly pathogenic, transmittable and invasive pneumococcal disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS...
32,707,573
Nature
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing.
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019 has triggered an ongoing global pandemic of the severe pneumonia-like disease coronavirus disease 2019 (COVID-19)(1). The development of a vaccine is likely to take at least 12-18 months, and the typical timeline for approval of a new...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Riva, Laura;Yuan, Shuofeng;Yin, Xin;Martin-Sancho, Laura;Matsunaga, Naoko;Pache, Lars;Burgstaller-Muehlbacher, Sebastian;De Jesus, Paul D;Teriete, Peter;Hull, Mitchell V;Chang, Max W;Chan, Jasper Fuk-Woo;Cao, Jianli;Poon, Vincent Kwok-Man;Herbert, Kristina M;Cheng, Kuoyuan;Nguyen, Tu-Trinh H;Rubanov, Andrey;Pu, Yuan;Ng...
10.1038/s41586-020-2577-1
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing. [Abstract]: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019 has triggered an ongoing global pandemic of the severe pneumonia-like disease coronavirus disease 2019 (COVID-19)(1). The developme...
32,534,687
Indian Heart J
Managing ACS during COVID-19 infection: Do not follow the traditional route.
COVID-19 pandemic is creating havoc in the world. It is also spreading in India creating a massive healthcare problem. Few major hospitals were closed down because of the spread among healthcare personnel. Management of several commonly occurring diseases needed modifications to a lesser or greater extent because of th...
acute coronary syndrome;covid-19
Journal Article;Review
Guha, Santanu;Mukhopadhay, Somnath;Karak, Avik;Choudhury, Basabendra;Kapoor, Aditya;Yadav, Rakesh
10.1016/j.ihj.2020.04.003
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Managing ACS during COVID-19 infection: Do not follow the traditional route. [Abstract]: COVID-19 pandemic is creating havoc in the world. It is also spreading in India creating a massive healthcare problem. Few major hospitals were closed down because of the spread among healthcare personnel. Management of se...
33,077,916
Nat Genet
Interferons and viruses induce a novel truncated ACE2 isoform and not the full-length SARS-CoV-2 receptor.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes COVID-19, utilizes angiotensin-converting enzyme 2 (ACE2) for entry into target cells. ACE2 has been proposed as an interferon-stimulated gene (ISG). Thus, interferon-induced variability in ACE2 expression levels could be important for susceptib...
Journal Article;Research Support, N.I.H., Extramural;Research Support, N.I.H., Intramural;Research Support, Non-U.S. Gov't
Onabajo, Olusegun O;Banday, A Rouf;Stanifer, Megan L;Yan, Wusheng;Obajemu, Adeola;Santer, Deanna M;Florez-Vargas, Oscar;Piontkivska, Helen;Vargas, Joselin M;Ring, Timothy J;Kee, Carmon;Doldan, Patricio;Tyrrell, D Lorne;Mendoza, Juan L;Boulant, Steeve;Prokunina-Olsson, Ludmila
10.1038/s41588-020-00731-9
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Interferons and viruses induce a novel truncated ACE2 isoform and not the full-length SARS-CoV-2 receptor. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes COVID-19, utilizes angiotensin-converting enzyme 2 (ACE2) for entry into target cells. ACE2 has been proposed as an i...
32,931,985
Semin Arthritis Rheum
Acute respiratory viral adverse events during use of antirheumatic disease therapies: A scoping review.
INTRODUCTION: COVID-19 is an acute respiratory viral infection that threatens people worldwide, including people with rheumatic disease, although it remains unclear to what extent various antirheumatic disease therapies increase susceptibility to complications of viral respiratory infections. OBJECTIVE: The present stu...
adverse event;antirheumatic medications;covid-19;immunosuppressive treatment;rheumatic disease;sars-cov-2
Journal Article;Research Support, Non-U.S. Gov't;Review
Kilian, Adam;Chock, Yu Pei;Huang, Irvin J;Graef, Elizabeth R;Upton, Laura A;Khilnani, Aneka;Krupnikova, Sonia D Silinsky;Almaghlouth, Ibrahim;Cappelli, Laura C;Fernandez-Ruiz, Ruth;Frankel, Brittany A;Frankovich, Jourdan;Harrison, Carly;Kumar, Bharat;Monga, Kanika;Vega, Jorge A Rosario;Singh, Namrata;Sparks, Jeffrey A;...
10.1016/j.semarthrit.2020.07.007
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Acute respiratory viral adverse events during use of antirheumatic disease therapies: A scoping review. [Abstract]: INTRODUCTION: COVID-19 is an acute respiratory viral infection that threatens people worldwide, including people with rheumatic disease, although it remains unclear to what extent various antirhe...
33,072,310
Ann Med Surg (Lond)
Public health prevention and emergency preparedness funding in the United States: Are we ready for the next pandemic?
*The CDC's cumulative funding for Public Health, Prevention, and Emergency Preparedness decreased over the course of 2011-2020, however, NIH funding dedicated to Prevention displayed an overall increase from 2008 to 2019.*The Hospital Preparedness Program (HPP) is the only source of federal funding for healthcare syste...
center for disease;control and prevention;emergency preparedness;pandemics;public health funding;public health policy
Editorial
Sen-Crowe, Brendon;McKenney, Mark;Elkbuli, Adel
10.1016/j.amsu.2020.10.007
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Public health prevention and emergency preparedness funding in the United States: Are we ready for the next pandemic? [Abstract]: *The CDC's cumulative funding for Public Health, Prevention, and Emergency Preparedness decreased over the course of 2011-2020, however, NIH funding dedicated to Prevention displaye...
32,510,105
J Nutr Health Aging
COVID-19: A Personalized Cardiometabolic Approach for Reducing Complications and Costs. The Role of Aging beyond Topics.
COVID 19 is much more than an infectious disease by SARS-CoV-2 followed by a disproportionate immune response. An older age, diabetes and history of cardiovascular disease, especially hypertension, but also chronic heart failure and coronary artery disease among others, are between the most important risk factors. In a...
metabolic syndrome;atherothrombotic disease;cardiometabolic health;cardiometabolic risk;cardiometabolic syndrome;endothelial dysfunction
Journal Article
Saban-Ruiz, J;Ly-Pen, D
10.1007/s12603-020-1385-5
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19: A Personalized Cardiometabolic Approach for Reducing Complications and Costs. The Role of Aging beyond Topics. [Abstract]: COVID 19 is much more than an infectious disease by SARS-CoV-2 followed by a disproportionate immune response. An older age, diabetes and history of cardiovascular disease, espec...
32,362,005
Biotechnol Appl Biochem
Correspondence: Importance of the validated serum biochemistry and hemogram parameters for rapid diagnosis and to prevent false negative results during COVID-19 pandemic.
COVID-19 threatens millions of lives, especially elderly population and people with chronic diseases including diabetes, hypertension, cancer, and cardiovascular diseases. Rapid and effective diagnoses are vital for the isolation of infected people and starting treatment immediately to stop the spread of COVID-19 virus...
covid-19;artificial intelligence;bioinformatics;hemogram;pandemic;serum biochemical parameters
Editorial
Aydemir, Duygu;Ulusu, Nuriye Nuray
10.1002/bab.1936
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Correspondence: Importance of the validated serum biochemistry and hemogram parameters for rapid diagnosis and to prevent false negative results during COVID-19 pandemic. [Abstract]: COVID-19 threatens millions of lives, especially elderly population and people with chronic diseases including diabetes, hyperte...
32,591,701
Br Dent J
Could we have prevented all this? A comparison of the British and South Korean primary dental care response to COVID-19.
To limit the spread of the novel coronavirus (COVID-19), Britain enforced a strict national lockdown, which is affecting the lives of millions, including dental professionals. As a result, all routine dental work has been suspended and general dental practitioners (GDPs) are inevitably faced with financial difficulties...
Journal Article
Noh, Kowoon;Loke, Jasmine;Kim, Kyungmin
10.1038/s41415-020-1705-5
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Could we have prevented all this? A comparison of the British and South Korean primary dental care response to COVID-19. [Abstract]: To limit the spread of the novel coronavirus (COVID-19), Britain enforced a strict national lockdown, which is affecting the lives of millions, including dental professionals. As...
32,365,233
Diabet Med
Guidelines for the management of diabetes services and patients during the COVID-19 pandemic.
The UK National Diabetes Inpatient COVID Response Group was formed at the end of March 2020 to support the provision of diabetes inpatient care during the COVID pandemic. It was formed in response to two emerging needs. First to ensure that basic diabetes services are secured and maintained at a time when there was a c...
Journal Article;Practice Guideline
Rayman, G;Lumb, A;Kennon, B;Cottrell, C;Nagi, D;Page, E;Voigt, D;Courtney, H;Atkins, H;Platts, J;Higgins, K;Dhatariya, K;Patel, M;Narendran, P;Kar, P;Newland-Jones, P;Stewart, R;Burr, O;Thomas, S
10.1111/dme.14316
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Guidelines for the management of diabetes services and patients during the COVID-19 pandemic. [Abstract]: The UK National Diabetes Inpatient COVID Response Group was formed at the end of March 2020 to support the provision of diabetes inpatient care during the COVID pandemic. It was formed in response to two e...
33,021,761
Turk J Med Sci
Cerebral hemodynamic alterations in patients with Covid-19.
BACKGROUND/AIM: Coronavirus 2019 disease (Covid-19) was first seen in December 2019 and afterwards it became a pandemic. Several systemic involvements have been reported in Covid-19 patients. In this study, it was aimed to investigate the cerebrovascular hemodynamics in patients with Covid-19. MATERIALS AND METHODS: Th...
blood flow velocity;covid-19;sars-cov-2;vasomotor reactivity
Journal Article
Sonkaya, AlI Riza;OztUrk, BIlgIn;KaradaS, Omer
10.3906/sag-2006-203
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Cerebral hemodynamic alterations in patients with Covid-19. [Abstract]: BACKGROUND/AIM: Coronavirus 2019 disease (Covid-19) was first seen in December 2019 and afterwards it became a pandemic. Several systemic involvements have been reported in Covid-19 patients. In this study, it was aimed to investigate the ...
32,991,573
Am J Case Rep
A 63-Year-Old Woman with SARS-CoV-2 Infection, Who Developed Severe COVID-19 Pneumonia and Was Supported with Convalescent Plasma Therapy.
BACKGROUND There is no evidence-based treatment for coronavirus disease 2019 (COVID-19). We report the case of a 63-year-old woman with SARS-CoV-2 infection who developed severe COVID-19 pneumonia and was treated with convalescent plasma. CASE REPORT A 63-year-old woman who presented with severe and prolonged course of...
Case Reports;Journal Article
Moniuszko-Malinowska, Anna;Czupryna, Piotr;Boczkowska-Radziwon, Barbara;Wasiluk, Tomasz;Borawski, Karol;Dunaj, Justyna;Bujno, Magdalena;Radziwon, Piotr;Rutkowski, Krzysztof;Pancewicz, Slawomir
10.12659/AJCR.927662
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: A 63-Year-Old Woman with SARS-CoV-2 Infection, Who Developed Severe COVID-19 Pneumonia and Was Supported with Convalescent Plasma Therapy. [Abstract]: BACKGROUND There is no evidence-based treatment for coronavirus disease 2019 (COVID-19). We report the case of a 63-year-old woman with SARS-CoV-2 infection who...
33,027,349
Cien Saude Colet
Risk factors associated with delay in diagnosis and mortality in patients with COVID-19 in the city of Rio de Janeiro, Brazil.
We investigated the predictors of delay in the diagnosis and mortality of patients with COVID-19 in Rio de Janeiro, Brazil. A cohort of 3,656 patients were evaluated (Feb-Apr 2020) and patients' sociodemographic characteristics, and social development index (SDI) were used as determinant factors of diagnosis delays and...
Journal Article
Cobre, Alexandre de Fatima;Boger, Beatriz;Fachi, Mariana Millan;Vilhena, Raquel de Oliveira;Domingos, Eric Luiz;Tonin, Fernanda Stumpf;Pontarolo, Roberto
10.1590/1413-812320202510.2.26882020
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Risk factors associated with delay in diagnosis and mortality in patients with COVID-19 in the city of Rio de Janeiro, Brazil. [Abstract]: We investigated the predictors of delay in the diagnosis and mortality of patients with COVID-19 in Rio de Janeiro, Brazil. A cohort of 3,656 patients were evaluated (Feb-A...
33,079,180
Clin Infect Dis
Clinical Characteristics and Outcomes of COVID-19 Patients Receiving Compassionate Use Leronlimab.
BACKGROUND: Leronlimab, a monoclonal antibody blocker of CCR5 originally developed to treat HIV-1 infection, was administered as an open label compassionate use therapeutic for COVID-19. METHODS: 23 hospitalized severe/critical COVID-19 patients received 700mg leronlimab subcutaneously, repeated after seven days in 17/...
covid-19;sars-cov-2;immunomodulatory therapy;leronlimab
Journal Article
Yang, Bryant;Fulcher, Jennifer A;Ahn, Jenny;Berro, Marlene;Goodman-Meza, David;Dhody, Kush;Sacha, Jonah B;Naeim, Arash;Yang, Otto O
10.1093/cid/ciaa1583
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical Characteristics and Outcomes of COVID-19 Patients Receiving Compassionate Use Leronlimab. [Abstract]: BACKGROUND: Leronlimab, a monoclonal antibody blocker of CCR5 originally developed to treat HIV-1 infection, was administered as an open label compassionate use therapeutic for COVID-19. METHODS: 23 h...
33,045,402
Contemp Clin Trials
The vitamin D for COVID-19 (VIVID) trial: A pragmatic cluster-randomized design.
OBJECTIVES: To determine the effect of vitamin D supplementation on disease progression and post-exposure prophylaxis for COVID-19 infection. We hypothesize that high-dose vitamin D3 supplementation will reduce risk of hospitalization/death among those with recently diagnosed COVID-19 infection and will reduce risk of ...
covid-19;cluster randomization;early treatment;prophylaxis;sars-cov-2;vitamin d
Clinical Trial Protocol;Journal Article;Randomized Controlled Trial;Research Support, Non-U.S. Gov't
Wang, Rui;DeGruttola, Victor;Lei, Quanhong;Mayer, Kenneth H;Redline, Susan;Hazra, Aditi;Mora, Samia;Willett, Walter C;Ganmaa, Davaasambuu;Manson, JoAnn E
10.1016/j.cct.2020.106176
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: The vitamin D for COVID-19 (VIVID) trial: A pragmatic cluster-randomized design. [Abstract]: OBJECTIVES: To determine the effect of vitamin D supplementation on disease progression and post-exposure prophylaxis for COVID-19 infection. We hypothesize that high-dose vitamin D3 supplementation will reduce risk of...
32,845,739
Hum Vaccin Immunother
Vaccines and routine immunization strategies during the COVID-19 pandemic.
Severe acute respiratory syndrome coronavirus 2 related disease (COVID-19) is now responsible for one of the most challenging and concerning pandemics. By August 2020, there were almost 20 million confirmed cases worldwide and well over half-million deaths. Since there is still no effective treatment or vaccine, non-ph...
covid-19;coronavirus;immunization;pandemic;vaccine
Journal Article;Review
Dinleyici, Ener Cagri;Borrow, Ray;Safadi, Marco Aurelio Palazzi;van Damme, Pierre;Munoz, Flor M
10.1080/21645515.2020.1804776
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Vaccines and routine immunization strategies during the COVID-19 pandemic. [Abstract]: Severe acute respiratory syndrome coronavirus 2 related disease (COVID-19) is now responsible for one of the most challenging and concerning pandemics. By August 2020, there were almost 20 million confirmed cases worldwide a...