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33,042,210 | Biomed Signal Process Control | MH-COVIDNet: Diagnosis of COVID-19 using deep neural networks and meta-heuristic-based feature selection on X-ray images. | COVID-19 is a disease that causes symptoms in the lungs and causes deaths around the world. Studies are ongoing for the diagnosis and treatment of this disease, which is defined as a pandemic. Early diagnosis of this disease is important for human life. This process is progressing rapidly with diagnostic studies based ... | bgwo;bpso;covid-19;deep learning models;pneumonia | Journal Article | Canayaz, Murat | 10.1016/j.bspc.2020.102257 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: MH-COVIDNet: Diagnosis of COVID-19 using deep neural networks and meta-heuristic-based feature selection on X-ray images. [Abstract]: COVID-19 is a disease that causes symptoms in the lungs and causes deaths around the world. Studies are ongoing for the diagnosis and treatment of this disease, which is defined... |
33,003,119 | Curr Opin Clin Nutr Metab Care | A brief discussion of the benefit and mechanism of vitamin D supplementation on coronavirus disease 2019. | PURPOSE OF REVIEW: Vitamin D exerts extraskeletal functions, including immunomodulatory activity, protection against respiratory tract infections and pleiotropic effects on the cardiovascular system. Since the outbreak of the coronavirus disease-2019 (COVID-19) pandemic, several articles have suggested the potential in... | Journal Article;Review | Cereda, Emanuele;Bogliolo, Laura;de Stefano, Ludovico;Caccialanza, Riccardo | 10.1097/MCO.0000000000000701 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: A brief discussion of the benefit and mechanism of vitamin D supplementation on coronavirus disease 2019. [Abstract]: PURPOSE OF REVIEW: Vitamin D exerts extraskeletal functions, including immunomodulatory activity, protection against respiratory tract infections and pleiotropic effects on the cardiovascular s... | |
32,404,170 | Reprod Biol Endocrinol | COVID-19 and assisted reproductive technology services: repercussions for patients and proposal for individualized clinical management. | The prolonged lockdown of health services providing high-complexity fertility treatments -as currently recommended by many reproductive medicine entities- is detrimental for society as a whole, and infertility patients in particular. Globally, approximately 0.3% of all infants born every year are conceived using assist... | assisted reproductive technology;covid-19;in vitro fertilization;infertility;intracytoplasmic sperm injection;poseidon criteria;viewpoint | Letter | Alviggi, Carlo;Esteves, Sandro C;Orvieto, Raoul;Conforti, Alessandro;La Marca, Antonio;Fischer, Robert;Andersen, Claus Y;Buhler, Klaus;Sunkara, Sesh K;Polyzos, Nikolaos P;Strina, Ida;Carbone, Luigi;Bento, Fabiola C;Galliano, Daniela;Yarali, Hakan;Vuong, Lan N;Grynberg, Michael;Drakopoulos, Panagiotis;Xavier, Pedro;Llac... | 10.1186/s12958-020-00605-z | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: COVID-19 and assisted reproductive technology services: repercussions for patients and proposal for individualized clinical management. [Abstract]: The prolonged lockdown of health services providing high-complexity fertility treatments -as currently recommended by many reproductive medicine entities- is detri... |
32,920,095 | Math Biosci | Modeling COVID-19 pandemic using Bayesian analysis with application to Slovene data. | In the paper, we propose a semiparametric framework for modeling the COVID-19 pandemic. The stochastic part of the framework is based on Bayesian inference. The model is informed by the actual COVID-19 data and the current epidemiological findings about the disease. The framework combines many available data sources (n... | bayesian inference;discrete renewal process;modeling epidemics;non-pharmaceutical interventions;reproduction number | Journal Article;Research Support, Non-U.S. Gov't;Validation Study | Manevski, Damjan;Ruzic Gorenjec, Nina;Kejzar, Natasa;Blagus, Rok | 10.1016/j.mbs.2020.108466 | [
0,
0,
1,
0,
0,
1,
0
] | [Title]: Modeling COVID-19 pandemic using Bayesian analysis with application to Slovene data. [Abstract]: In the paper, we propose a semiparametric framework for modeling the COVID-19 pandemic. The stochastic part of the framework is based on Bayesian inference. The model is informed by the actual COVID-19 data and the... |
32,555,388 | Nature | Convergent antibody responses to SARS-CoV-2 in convalescent individuals. | During the coronavirus disease-2019 (COVID-19) pandemic, severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) has led to the infection of millions of people and has claimed hundreds of thousands of lives. The entry of the virus into cells depends on the receptor-binding domain (RBD) of the spike (S) pro... | Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't | Robbiani, Davide F;Gaebler, Christian;Muecksch, Frauke;Lorenzi, Julio C C;Wang, Zijun;Cho, Alice;Agudelo, Marianna;Barnes, Christopher O;Gazumyan, Anna;Finkin, Shlomo;Hagglof, Thomas;Oliveira, Thiago Y;Viant, Charlotte;Hurley, Arlene;Hoffmann, Hans-Heinrich;Millard, Katrina G;Kost, Rhonda G;Cipolla, Melissa;Gordon, Kri... | 10.1038/s41586-020-2456-9 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Convergent antibody responses to SARS-CoV-2 in convalescent individuals. [Abstract]: During the coronavirus disease-2019 (COVID-19) pandemic, severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) has led to the infection of millions of people and has claimed hundreds of thousands of lives. The e... | |
32,893,069 | Neurologia | Case fatality of COVID-19 in patients with neurodegenerative dementia. | INTRODUCTION: The elderly population is the group most threatened by COVID-19, with the highest mortality rates. This study aims to analyse the case fatality of COVID-19 in a cohort of patients with degenerative dementia. METHODS: We conducted a descriptive case-control study of a sample of patients diagnosed with prim... | covid-19;case fatality;demencias;dementia;letalidad;sars-cov-2 | Journal Article | Reyes-Bueno, J A;Mena-Vazquez, N;Ojea-Ortega, T;Gonzalez-Sotomayor, M M;Cabezudo-Garcia, P;Ciano-Petersen, N L;Pons-Pons, G;Castro-Sanchez, M V;Serrano-Castro, P J | 10.1016/j.nrl.2020.07.005 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Case fatality of COVID-19 in patients with neurodegenerative dementia. [Abstract]: INTRODUCTION: The elderly population is the group most threatened by COVID-19, with the highest mortality rates. This study aims to analyse the case fatality of COVID-19 in a cohort of patients with degenerative dementia. METHOD... |
33,012,349 | Mayo Clin Proc | COVID-19 and Sex Differences: Mechanisms and Biomarkers. | Men are consistently overrepresented in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and coronavirus disease 2019 (COVID-19) severe outcomes, including higher fatality rates. These differences are likely due to gender-specific behaviors, genetic and hormonal factors, and sex differences in bi... | Journal Article;Research Support, N.I.H., Extramural;Review | Haitao, Tu;Vermunt, Jane V;Abeykoon, Jithma;Ghamrawi, Ranine;Gunaratne, Madugodaralalage;Jayachandran, Muthuvel;Narang, Kavita;Parashuram, Santosh;Suvakov, Sonja;Garovic, Vesna D | 10.1016/j.mayocp.2020.07.024 | [
1,
1,
0,
1,
0,
0,
0
] | [Title]: COVID-19 and Sex Differences: Mechanisms and Biomarkers. [Abstract]: Men are consistently overrepresented in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and coronavirus disease 2019 (COVID-19) severe outcomes, including higher fatality rates. These differences are likely due to gend... | |
32,768,466 | J Pediatr | Multisystem Inflammatory Syndrome in Children Associated with Severe Acute Respiratory Syndrome Coronavirus 2: A Systematic Review. | OBJECTIVE: To develop a more comprehensive description of multisystem inflammatory syndrome in children (MIS-C), a novel syndrome linked to severe acute respiratory syndrome coronavirus 2, by conducting a systematic analysis of studies from different settings that used various inclusion criteria. STUDY DESIGN: MIS-C st... | Journal Article | Abrams, Joseph Y;Godfred-Cato, Shana E;Oster, Matthew E;Chow, Eric J;Koumans, Emilia H;Bryant, Bobbi;Leung, Jessica W;Belay, Ermias D | 10.1016/j.jpeds.2020.08.003 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Multisystem Inflammatory Syndrome in Children Associated with Severe Acute Respiratory Syndrome Coronavirus 2: A Systematic Review. [Abstract]: OBJECTIVE: To develop a more comprehensive description of multisystem inflammatory syndrome in children (MIS-C), a novel syndrome linked to severe acute respiratory sy... | |
32,352,911 | Glob Public Health | COVID-19 reveals weak health systems by design: Why we must re-make global health in this historic moment. | The COVID-19 pandemic demonstrates the critical need to reimagine and repair the broken systems of global health. Specifically, the pandemic demonstrates the hollowness of the global health rhetoric of equity, the weaknesses of a health security-driven global health agenda, and the negative health impacts of power diff... | covid;global health collaboration;global health equity;global health partnership;pandemic | Journal Article;Video-Audio Media | Shamasunder, Sriram;Holmes, Seth M;Goronga, Tinashe;Carrasco, Hector;Katz, Elyse;Frankfurter, Raphael;Keshavjee, Salmaan | 10.1080/17441692.2020.1760915 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: COVID-19 reveals weak health systems by design: Why we must re-make global health in this historic moment. [Abstract]: The COVID-19 pandemic demonstrates the critical need to reimagine and repair the broken systems of global health. Specifically, the pandemic demonstrates the hollowness of the global health rh... |
32,762,609 | Monoclon Antib Immunodiagn Immunother | A Novel Hypothesis for Original Antigenic Sin in the Severe Disease of SARS-CoV-2 Infection. | In this hypothesis, we address the biological/immunological pathway leading to severe disease or death after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The underlying immune response is described with "original antigenic sin" (OAS) whereby previous infections influence the response to ... | sars-cov-2;coronavirus;original antigenic sin | Journal Article | Kohler, Heinz;Nara, Peter | 10.1089/mab.2020.0029 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: A Novel Hypothesis for Original Antigenic Sin in the Severe Disease of SARS-CoV-2 Infection. [Abstract]: In this hypothesis, we address the biological/immunological pathway leading to severe disease or death after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The underlying immun... |
32,403,008 | J Clin Virol | A RT-PCR assay for the detection of coronaviruses from four genera. | BACKGROUND: During the past two decades, three novel coronaviruses (CoVs) have emerged to cause international human epidemics with severe morbidity. CoVs have also emerged to cause severe epidemics in animals. A better understanding of the natural hosts and genetic diversity of CoVs are needed to help mitigate these th... | covid-19;coronavirus;emerging;infectious diseases;sars-cov-2 | Evaluation Study;Journal Article | Xiu, Leshan;Binder, Raquel A;Alarja, Natalie A;Kochek, Kara;Coleman, Kristen K;Than, Son T;Bailey, Emily S;Bui, Vuong N;Toh, Teck-Hock;Erdman, Dean D;Gray, Gregory C | 10.1016/j.jcv.2020.104391 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: A RT-PCR assay for the detection of coronaviruses from four genera. [Abstract]: BACKGROUND: During the past two decades, three novel coronaviruses (CoVs) have emerged to cause international human epidemics with severe morbidity. CoVs have also emerged to cause severe epidemics in animals. A better understandin... |
32,885,293 | Eur J Clin Microbiol Infect Dis | Evaluation of three commercial assays for SARS-CoV-2 molecular detection in upper respiratory tract samples. | The increasing COVID-19 widespread has created the necessity to assess the diagnostic accuracy of newly introduced (RT-PCR based) assays for SARS-CoV-2 RNA detection in respiratory tract samples. We compared the results of the Allplex 2019-nCoV assay with those of the Simplexa COVID-19 Direct assay and the Quanty COVID... | covid-19;molecular assay;respiratory samples;sars-cov-2;viral rna load | Comparative Study;Evaluation Study;Journal Article | Liotti, Flora Marzia;Menchinelli, Giulia;Marchetti, Simona;Morandotti, Grazia Angela;Sanguinetti, Maurizio;Posteraro, Brunella;Cattani, Paola | 10.1007/s10096-020-04025-0 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Evaluation of three commercial assays for SARS-CoV-2 molecular detection in upper respiratory tract samples. [Abstract]: The increasing COVID-19 widespread has created the necessity to assess the diagnostic accuracy of newly introduced (RT-PCR based) assays for SARS-CoV-2 RNA detection in respiratory tract sam... |
32,683,320 | Diabetes Metab Syndr | Pros and cons for use of statins in people with coronavirus disease-19 (COVID-19). | BACKGROUND AND AIMS: Morbidity and mortality from coronavirus disease 2019 (COVID-19) is higher among people with diabetes mellitus (DM), hypertension, and cardiovascular disease (CVD). Statins are used in the majority of people with DM and CVD. This mini-review discusses the current understanding of benefit-risk ratio... | coronavirus disease-19 (covid-19);diabetes mellitus;oxidative stress;severe acute respiratory syndrome-coronavirus2 (sars-cov2);statins | Journal Article;Review | Subir, Ray;Jagat J, Mukherjee;Kalyan K, Gangopadhyay | 10.1016/j.dsx.2020.07.011 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Pros and cons for use of statins in people with coronavirus disease-19 (COVID-19). [Abstract]: BACKGROUND AND AIMS: Morbidity and mortality from coronavirus disease 2019 (COVID-19) is higher among people with diabetes mellitus (DM), hypertension, and cardiovascular disease (CVD). Statins are used in the majori... |
32,836,446 | Public Adm Rev | Fighting Against COVID-19 through Government Initiatives and Collaborative Governance: Taiwan Experience. | Taiwan is situated less than 200 km from the first Covid-19 outbreak state, China, and has millions of international visitors yearly. Taiwan's collective efforts to block and eliminate the invisible enemy (Covid-19) from the island, have resulted in relatively low infection and death numbers, and were hailed as a succe... | covid-19;collaborative governance | Journal Article | Huang, Irving Yi-Feng | 10.1111/puar.13239 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Fighting Against COVID-19 through Government Initiatives and Collaborative Governance: Taiwan Experience. [Abstract]: Taiwan is situated less than 200 km from the first Covid-19 outbreak state, China, and has millions of international visitors yearly. Taiwan's collective efforts to block and eliminate the invi... |
32,443,856 | Diagnostics (Basel) | Electronic Health Information Systems to Improve Disease Diagnosis and Management at Point-of-Care in Low and Middle Income Countries: A Narrative Review. | The purpose of an electronic health information system (EHIS) is to support health care workers in providing health care services to an individual client and to enable data exchange among service providers. The demand to explore the use of EHIS for diagnosis and management of communicable and non-communicable diseases ... | diagnosis;electronic health information system;low and middle income countries;point-of-care;treatment | Journal Article;Review | Khubone, Thokozani;Tlou, Boikhutso;Mashamba-Thompson, Tivani Phosa | 10.3390/diagnostics10050327 | [
0,
1,
1,
0,
0,
0,
0
] | [Title]: Electronic Health Information Systems to Improve Disease Diagnosis and Management at Point-of-Care in Low and Middle Income Countries: A Narrative Review. [Abstract]: The purpose of an electronic health information system (EHIS) is to support health care workers in providing health care services to an individu... |
32,568,471 | Am J Transplant | There are no best practices in a pandemic: Organ donation within the COVID-19 epicenter. | LiveOnNY, the organ procurement organization (OPO) for the greater New York metropolitan area, suspended several best practices to manage the rising referrals of deaths from hospitals during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. On April 2, 2020 hospitals in the donor service area w... | clinical research/ practice;donors and donation: deceased;infection and infectious agents - viral;organ procurement and allocation;organ procurement organization;social sciences | Journal Article | Friedman, Amy L;Delli Carpini, Kristin W;Ezzell, Chad;Irving, Helen | 10.1111/ajt.16157 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: There are no best practices in a pandemic: Organ donation within the COVID-19 epicenter. [Abstract]: LiveOnNY, the organ procurement organization (OPO) for the greater New York metropolitan area, suspended several best practices to manage the rising referrals of deaths from hospitals during the severe acute re... |
32,265,007 | Euro Surveill | Whole genome and phylogenetic analysis of two SARS-CoV-2 strains isolated in Italy in January and February 2020: additional clues on multiple introductions and further circulation in Europe. | Whole genome sequences of SARS-CoV-2 obtained from two patients, a Chinese tourist visiting Rome and an Italian, were compared with sequences from Europe and elsewhere. In a phylogenetic tree, the Italian patient's sequence clustered with sequences from Germany while the tourist's sequence clustered with other European... | europe;sars-cov-2;whole genome sequence;phylogenetic analysis | Journal Article | Stefanelli, Paola;Faggioni, Giovanni;Lo Presti, Alessandra;Fiore, Stefano;Marchi, Antonella;Benedetti, Eleonora;Fabiani, Concetta;Anselmo, Anna;Ciammaruconi, Andrea;Fortunato, Antonella;De Santis, Riccardo;Fillo, Silvia;Capobianchi, Maria Rosaria;Gismondo, Maria Rita;Ciervo, Alessandra;Rezza, Giovanni;Castrucci, Maria ... | 10.2807/1560-7917.ES.2020.25.13.2000305 | [
0,
0,
0,
1,
0,
0,
0
] | [Title]: Whole genome and phylogenetic analysis of two SARS-CoV-2 strains isolated in Italy in January and February 2020: additional clues on multiple introductions and further circulation in Europe. [Abstract]: Whole genome sequences of SARS-CoV-2 obtained from two patients, a Chinese tourist visiting Rome and an Ital... |
32,822,430 | PLoS One | Diagnostic and prognostic value of hematological and immunological markers in COVID-19 infection: A meta-analysis of 6320 patients. | OBJECTIVE: Evidence-based characterization of the diagnostic and prognostic value of the hematological and immunological markers related to the epidemic of Coronavirus Disease 2019 (COVID-19) is critical to understand the clinical course of the infection and to assess in development and validation of biomarkers. METHOD... | Journal Article;Meta-Analysis;Systematic Review | Elshazli, Rami M;Toraih, Eman A;Elgaml, Abdelaziz;El-Mowafy, Mohammed;El-Mesery, Mohamed;Amin, Mohamed N;Hussein, Mohammad H;Killackey, Mary T;Fawzy, Manal S;Kandil, Emad | 10.1371/journal.pone.0238160 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Diagnostic and prognostic value of hematological and immunological markers in COVID-19 infection: A meta-analysis of 6320 patients. [Abstract]: OBJECTIVE: Evidence-based characterization of the diagnostic and prognostic value of the hematological and immunological markers related to the epidemic of Coronavirus... | |
32,764,693 | Nat Commun | Morphogenesis and cytopathic effect of SARS-CoV-2 infection in human airway epithelial cells. | SARS-CoV-2, a beta-coronavirus, has rapidly spread across the world, highlighting its high transmissibility, but the underlying morphogenesis and pathogenesis remain poorly understood. Here, we characterize the replication dynamics, cell tropism and morphogenesis of SARS-CoV-2 in organotypic human airway epithelial (HA... | Journal Article;Research Support, Non-U.S. Gov't | Zhu, Na;Wang, Wenling;Liu, Zhidong;Liang, Chaoyang;Wang, Wen;Ye, Fei;Huang, Baoying;Zhao, Li;Wang, Huijuan;Zhou, Weimin;Deng, Yao;Mao, Longfei;Su, Chongyu;Qiang, Guangliang;Jiang, Taijiao;Zhao, Jincun;Wu, Guizhen;Song, Jingdong;Tan, Wenjie | 10.1038/s41467-020-17796-z | [
0,
0,
0,
1,
0,
0,
0
] | [Title]: Morphogenesis and cytopathic effect of SARS-CoV-2 infection in human airway epithelial cells. [Abstract]: SARS-CoV-2, a beta-coronavirus, has rapidly spread across the world, highlighting its high transmissibility, but the underlying morphogenesis and pathogenesis remain poorly understood. Here, we characteriz... | |
32,725,209 | Age Ageing | COVID-19 outbreak: organisation of a geriatric assessment and coordination unit. A French example. | Older people are particularly affected by the COVID-19 outbreak because of their vulnerability as well as the complexity of health organisations, particularly in the often-compartmentalised interactions between community, hospital and nursing home actors. In this endemic situation, with massive flows of patients requir... | covid-19;decision-making;ethics;geriatrics;healthcare organisation;older people;palliative care | Journal Article | Koeberle, Severine;Tannou, Thomas;Bouiller, Kevin;Becoulet, Nicolas;Outrey, Justin;Chirouze, Catherine;Aubry, Regis | 10.1093/ageing/afaa092 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: COVID-19 outbreak: organisation of a geriatric assessment and coordination unit. A French example. [Abstract]: Older people are particularly affected by the COVID-19 outbreak because of their vulnerability as well as the complexity of health organisations, particularly in the often-compartmentalised interactio... |
32,563,080 | Int J Pediatr Otorhinolaryngol | The otolaryngologist's and anesthesiologist's collaborative role in a pandemic: A large quaternary pediatric center's experience with COVID-19 preparation and simulation. | There has been a rapid global spread of a novel coronavirus, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which originated in Wuhan China in late 2019. A serious threat of nosocomial spread exists and as such, there is a critical necessity for well-planned and rehearsed processes during the care of... | airway;anesthesia;covid-19;coronavirus;otolaryngology;simulation | Journal Article | Willer, Brittany L;Thung, Arlyne K;Corridore, Marco;D'Mello, Ajay J;Schloss, Brian S;Malhotra, Prashant S;Walz, Patrick C;Elmaraghy, Charles A;Tobias, Joseph D;Jatana, Kris R;Raman, Vidya T | 10.1016/j.ijporl.2020.110174 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: The otolaryngologist's and anesthesiologist's collaborative role in a pandemic: A large quaternary pediatric center's experience with COVID-19 preparation and simulation. [Abstract]: There has been a rapid global spread of a novel coronavirus, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), w... |
32,983,456 | Multidiscip Respir Med | High-flow nasal cannula for Acute Respiratory Distress Syndrome (ARDS) due to COVID-19. | Introduction: High-flow nasal cannula oxygen therapy (HFNC) has been shown to be a useful therapy in the treatment of patients with Acute Respiratory Distress Syndrome (ARDS), but its efficacy is still unknown in patients with COVID-19. Our objective is to describe its utility as therapy for the treatment of ARDS cause... | covid-19;acute respiratory distress syndrome;coronavirus;high-flow nasal cannula | Journal Article | Panadero, Carolina;Abad-Fernandez, Araceli;Rio-Ramirez, M feminine Teresa;Acosta Gutierrez, Carmen Maria;Calderon-Alcala, Mariara;Lopez-Riolobos, Cristina;Matesanz-Lopez, Cristina;Garcia-Prieto, Fernando;Diaz-Garcia, Jose Maria;Raboso-Moreno, Beatriz;Vasquez-Gambasica, Zully;Andres-Ruzafa, Pilar;Garcia-Satue, Jose Luis... | 10.4081/mrm.2020.693 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: High-flow nasal cannula for Acute Respiratory Distress Syndrome (ARDS) due to COVID-19. [Abstract]: Introduction: High-flow nasal cannula oxygen therapy (HFNC) has been shown to be a useful therapy in the treatment of patients with Acute Respiratory Distress Syndrome (ARDS), but its efficacy is still unknown i... |
32,736,007 | Biol Blood Marrow Transplant | Guidelines for COVID-19 Management in Hematopoietic Cell Transplantation and Cellular Therapy Recipients. | There are currently limited data on the epidemiology, clinical manifestations, and optimal management of Coronavirus Disease 2019 (COVID-19) in hematopoietic cell transplantation and cellular therapy recipients. Given the experience with other respiratory viruses, we anticipate that patients may develop severe clinical... | covid-19;sars-cov-2;cellular therapy;hematopoietic cell transplan | Practice Guideline;Research Support, Non-U.S. Gov't | Waghmare, Alpana;Abidi, Maheen Z;Boeckh, Michael;Chemaly, Roy F;Dadwal, Sanjeet;El Boghdadly, Zeinab;Kamboj, Mini;Papanicolaou, Genovefa A;Pergam, Steven A;Shahid, Zainab | 10.1016/j.bbmt.2020.07.027 | [
1,
0,
1,
0,
0,
0,
0
] | [Title]: Guidelines for COVID-19 Management in Hematopoietic Cell Transplantation and Cellular Therapy Recipients. [Abstract]: There are currently limited data on the epidemiology, clinical manifestations, and optimal management of Coronavirus Disease 2019 (COVID-19) in hematopoietic cell transplantation and cellular t... |
32,839,751 | SN Compr Clin Med | Labile PT-INR in a Covid-19 Patient Under Long-term Vitamin K Antagonist Therapy: a Case Report. | The COronaVIrus Disease-19 (COVID-19) has been associated with thromboembolic complications, but evidence on its impact on hemorrhagic risk are still scarce. We describe a case of COVID-19 with hemorrhagic complication in the post-acute phase of the disease. The patient was a 93-year-old woman admitted to a post-acute ... | covid-19;case report;hemorrhagic risk;oral anticoagulation | Journal Article | Trevisan, Caterina;Miconi, Lorella;Barbierato, Emanuele;Marinaro, Giuseppe;Targhetta, Stefano;D'agata, Mario;Rinaldi, Daniela | 10.1007/s42399-020-00460-4 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Labile PT-INR in a Covid-19 Patient Under Long-term Vitamin K Antagonist Therapy: a Case Report. [Abstract]: The COronaVIrus Disease-19 (COVID-19) has been associated with thromboembolic complications, but evidence on its impact on hemorrhagic risk are still scarce. We describe a case of COVID-19 with hemorrha... |
32,853,988 | EBioMedicine | Clinical, immunological and virological characterization of COVID-19 patients that test re-positive for SARS-CoV-2 by RT-PCR. | BACKGROUND: Some COVID-19 cases test positive again for SARS-CoV-2 RNA following negative test results and discharge, raising questions about the meaning of virus detection. Better characterization of re-positive cases is urgently needed. METHODS: Clinical data were obtained through Guangdong's COVID-19 surveillance ne... | covid-19;neutralizing antibody;re-positive;sars-cov-2;virology | Journal Article | Lu, Jing;Peng, Jinju;Xiong, Qianling;Liu, Zhe;Lin, Huifang;Tan, Xiaohua;Kang, Min;Yuan, Runyu;Zeng, Lilian;Zhou, Pingping;Liang, Chumin;Yi, Lina;du Plessis, Louis;Song, Tie;Ma, Wenjun;Sun, Jiufeng;Pybus, Oliver G;Ke, Changwen | 10.1016/j.ebiom.2020.102960 | [
0,
1,
0,
0,
1,
0,
0
] | [Title]: Clinical, immunological and virological characterization of COVID-19 patients that test re-positive for SARS-CoV-2 by RT-PCR. [Abstract]: BACKGROUND: Some COVID-19 cases test positive again for SARS-CoV-2 RNA following negative test results and discharge, raising questions about the meaning of virus detection.... |
32,568,064 | Acta Med Port | [Respiratory and Facial Protection: Current Perspectives in the Context of the COVID-19 Pandemic]. | The new SARS-CoV-2 pandemic is an example of an international public health emergency, which is associated with considerable social and economic challenges. At the healthcare level there is the risk that nosocomial outbreaks can be local amplifiers. Adequate infection control practices are of critical importance, which... | covid-19;masks;personal protective equipment;respiratory protective devices;sars-cov-2 | Journal Article;Review | Peres, David;Boleo-Tome, Jose Pedro;Santos, Gilda | 10.20344/amp.14108 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: [Respiratory and Facial Protection: Current Perspectives in the Context of the COVID-19 Pandemic]. [Abstract]: The new SARS-CoV-2 pandemic is an example of an international public health emergency, which is associated with considerable social and economic challenges. At the healthcare level there is the risk t... |
32,582,327 | Pak J Med Sci | COVID-19 Pandemic & Skin Care Guidelines for Health Care Professionals. | The Novel corona virus is bringing multiple challenges for health care professionals. Skin is the biggest organ and the first line of defense against different infections and external factors. Being the front line warriors, health care professionals are susceptible to various skin conditions due to prolonged use of per... | corona;dermatitis;protective equipment;skin care | Journal Article | Masood, Sadia;Tabassum, Saadia;Naveed, Shaheen;Jalil, Palwasha | 10.12669/pjms.36.COVID19-S4.2748 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: COVID-19 Pandemic & Skin Care Guidelines for Health Care Professionals. [Abstract]: The Novel corona virus is bringing multiple challenges for health care professionals. Skin is the biggest organ and the first line of defense against different infections and external factors. Being the front line warriors, hea... |
32,623,040 | Diabetes Res Clin Pract | The impact of COVID-19 on people with diabetes in Brazil. | The present study aims at identifying main barriers faced by people living with diabetes in Brazil during the COVID-19 pandemic. METHODS: In a convenience sampling study, data were collected from 1701 individuals, aged 18 or above; 75.54% female participants; 60.73% T1D and 30.75% T2D, between April 22nd and May 4th, u... | brazil;covid-19;coronavirus;diabetes;pandemic;sars-cov-2 | Journal Article | Barone, Mark Thomaz Ugliara;Harnik, Simone Bega;de Luca, Patricia Vieira;Lima, Bruna Leticia de Souza;Wieselberg, Ronaldo Jose Pineda;Ngongo, Belinda;Pedrosa, Hermelinda Cordeiro;Pimazoni-Netto, Augusto;Franco, Denise Reis;Marinho de Souza, Maria de Fatima;Malta, Deborah Carvalho;Giampaoli, Viviana | 10.1016/j.diabres.2020.108304 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: The impact of COVID-19 on people with diabetes in Brazil. [Abstract]: The present study aims at identifying main barriers faced by people living with diabetes in Brazil during the COVID-19 pandemic. METHODS: In a convenience sampling study, data were collected from 1701 individuals, aged 18 or above; 75.54% fe... |
32,923,230 | Cureus | Concurrent Diagnosis of Acute Myeloid Leukemia and COVID-19: A Management Challenge. | The emergence of coronavirus disease 2019 (COVID-19) has created new challenges in the management of serious diseases. We describe a 41-year-old male who presented with fever, watery diarrhea, and epistaxis. Initial workup revealed pancytopenia with >50% blasts on the peripheral smear raising suspicion of acute myeloid... | acute myeloblastic leukemia;acute myeloid leukemia (aml);convalescent plasma therapy;corona virus disease 2019;covid 19;novel corona virus;remdesivir | Case Reports | Khan, Abdul Moiz;Ajmal, Zainub;Raval, Mihir;Tobin, Ellis | 10.7759/cureus.9629 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Concurrent Diagnosis of Acute Myeloid Leukemia and COVID-19: A Management Challenge. [Abstract]: The emergence of coronavirus disease 2019 (COVID-19) has created new challenges in the management of serious diseases. We describe a 41-year-old male who presented with fever, watery diarrhea, and epistaxis. Initia... |
32,931,509 | PLoS One | Evaluating approaches to designing effective Co-Created hand-hygiene interventions for children in India, Sierra Leone and the UK. | Effective and culturally appropriate hand-hygiene education is essential to promote health-related practices to control and prevent diseases such as Diarrhoea, Ebola and COVID-19. In this paper we outline and evaluate the Co-Creation processes underpinning a handwashing intervention for young children (A Germ's Journey... | Journal Article;Research Support, Non-U.S. Gov't | Crosby, Sapphire;Younie, Sarah;Williamson, Iain;Laird, Katie | 10.1371/journal.pone.0239234 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Evaluating approaches to designing effective Co-Created hand-hygiene interventions for children in India, Sierra Leone and the UK. [Abstract]: Effective and culturally appropriate hand-hygiene education is essential to promote health-related practices to control and prevent diseases such as Diarrhoea, Ebola an... | |
33,013,809 | Front Microbiol | Comprehensive Genome Analysis of 6,000 USA SARS-CoV-2 Isolates Reveals Haplotype Signatures and Localized Transmission Patterns by State and by Country. | Genomic analysis of SARS-CoV-2 sequences is crucial in determining the effectiveness of prudent safer at home measures in the United States (US). By haplotype analysis of 6,356 US isolates, we identified a pattern of strongly localized outbreaks at the city-, state-, and country-levels, and temporal transmissions. This... | covid-19;sars-cov-2;haplotype;localized outbreak;temporal transmission;variant | Journal Article | Shen, Lishuang;Dien Bard, Jennifer;Biegel, Jaclyn A;Judkins, Alexander R;Gai, Xiaowu | 10.3389/fmicb.2020.573430 | [
0,
0,
1,
1,
1,
0,
0
] | [Title]: Comprehensive Genome Analysis of 6,000 USA SARS-CoV-2 Isolates Reveals Haplotype Signatures and Localized Transmission Patterns by State and by Country. [Abstract]: Genomic analysis of SARS-CoV-2 sequences is crucial in determining the effectiveness of prudent safer at home measures in the United States (US). ... |
32,500,339 | Forensic Sci Med Pathol | The craniotomy box: an innovative method of containing hazardous aerosols generated during skull saw use in autopsy on a COVID-19 body. | During a disease pandemic, there is still a requirement to perform postmortem examinations within the context of legal considerations. The management of the dead from COVID-19 should not impede the medicolegal investigation of the death where required by the authorities and legislation but additional health and safety ... | aerosol-generating procedure;autopsy;covid-19;craniotomy box;safe alternative | Journal Article | Hasmi, Ahmad Hafizam;Khoo, Lay See;Koo, Zhao Peng;Suriani, Muhammad Uzair Ahmad;Hamdan, Ain Nurfarahana;Yaro, Siti Wira Md;Arshad, Salmah;Siew, Sheue Feng;Ibrahim, Mohamad Azaini;Mahmood, Mohd Shah | 10.1007/s12024-020-00270-z | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: The craniotomy box: an innovative method of containing hazardous aerosols generated during skull saw use in autopsy on a COVID-19 body. [Abstract]: During a disease pandemic, there is still a requirement to perform postmortem examinations within the context of legal considerations. The management of the dead f... |
32,963,907 | Cureus | Hamman-Rich Syndrome: A Diagnosis of Exclusion in the COVID-19 Pandemic. | Hamman-Rich syndrome is a rapidly progressive interstitial lung disease with acute respiratory distress syndrome physiology. It carries a grave prognosis and a high early mortality rate. It is often distinguished from other similar pulmonary pathologies based on the clinical course, laboratory findings, bronchoalveolar... | acute interstitial pneumonia;acute respiratory distress syndrome [ards];hamman-rich syndrome;idiopathic interstitial pneumonia | Case Reports | Zhang, Qian;Raza, Ahmad;Chan, Vincent;Minalyan, Artem;Madara, John | 10.7759/cureus.9866 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Hamman-Rich Syndrome: A Diagnosis of Exclusion in the COVID-19 Pandemic. [Abstract]: Hamman-Rich syndrome is a rapidly progressive interstitial lung disease with acute respiratory distress syndrome physiology. It carries a grave prognosis and a high early mortality rate. It is often distinguished from other si... |
32,799,197 | Neonatology | Managing Preterm Infants Born to COVID-19 Mothers: Evidence from a Retrospective Cohort Study in Wuhan, China. | BACKGROUND: COVID-19 has spread rapidly over the world. Little is known about the outcomes of infections in pregnant women. The management and characteristics of preterm infants born to COVID-19 mothers need to be clarified. METHODS: In this retrospective, single-center cohort study, we describe the clinical courses of... | covid-19 mothers;clinical outcomes;preterm infants | Case Reports;Journal Article;Research Support, Non-U.S. Gov't | Hu, Xiaolin;Gao, Jinzhi;Wei, Ying;Chen, Hui;Sun, Xuan;Chen, Juan;Luo, Xiaoping;Chen, Ling | 10.1159/000509141 | [
0,
0,
1,
0,
1,
0,
0
] | [Title]: Managing Preterm Infants Born to COVID-19 Mothers: Evidence from a Retrospective Cohort Study in Wuhan, China. [Abstract]: BACKGROUND: COVID-19 has spread rapidly over the world. Little is known about the outcomes of infections in pregnant women. The management and characteristics of preterm infants born to CO... |
32,790,075 | J Med Virol | Late onset infectious complications and safety of tocilizumab in the management of COVID-19. | BACKGROUND: Tocilizumab (TCZ) has been used in the management of COVID-19-related cytokine release syndrome (CRS). Concerns exist regarding the risk of infections and drug-related toxicities. We sought to evaluate the incidence of these TCZ complications among COVID-19 patients. METHODS: All adult inpatients with COVID... | il-6 inhibition;sars coronavirus;coronavirus;cytokine/chemokine;immune responses;tocilizumab | Journal Article | Pettit, Natasha N;Nguyen, Cynthia T;Mutlu, Gokhan M;Wu, David;Kimmig, Lucas;Pitrak, David;Pursell, Kenneth | 10.1002/jmv.26429 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Late onset infectious complications and safety of tocilizumab in the management of COVID-19. [Abstract]: BACKGROUND: Tocilizumab (TCZ) has been used in the management of COVID-19-related cytokine release syndrome (CRS). Concerns exist regarding the risk of infections and drug-related toxicities. We sought to e... |
32,959,015 | Open Forum Infect Dis | Development of a Standardized Data Collection Tool for Evaluation and Management of Coronavirus Disease 2019. | Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 ) is responsible for coronavirus disease 2019 (COVID-19), a disease that had not been previously described and for which clinicians need to rapidly adapt their daily practice. The novelty of SARS-CoV-2 produced significant gaps in harmonization of ... | coronavirus-19;data collection tool;hospitalized | Journal Article | Morris, Stephen R;Natori, Yoichiro;Salguero, Douglas;Mantero, Alejandro;Ma, Ruixuan;de Lima Corvino, Daniela F;Fernandez, Anmary;Lazo, Alex;Vu, Christine A;Bjork, Lauren;Serota, David;Quevedo, Jennifer;Vega, Ana;Maxam, Meshell;DeRonde, Kailynn;Barreiro, Pablo;Raccamarich, Patricia;Alvarez, Maria Romero;Skiada, Dimitra;... | 10.1093/ofid/ofaa320 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Development of a Standardized Data Collection Tool for Evaluation and Management of Coronavirus Disease 2019. [Abstract]: Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 ) is responsible for coronavirus disease 2019 (COVID-19), a disease that had not been previously described and for wh... |
32,489,724 | Cureus | Basal Ganglia Involvement and Altered Mental Status: A Unique Neurological Manifestation of Coronavirus Disease 2019. | Like other respiratory viruses, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may enter the central nervous system (CNS) via the hematogenous or neuronal path. However, neurological complications of coronavirus disease 2019 (COVID-19) have not been reported frequently. Encephalopathy has been described a... | altered mental state;basal ganglia;case report;covid-19 | Case Reports | Haddadi, Kaveh;Ghasemian, Roya;Shafizad, Misagh | 10.7759/cureus.7869 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Basal Ganglia Involvement and Altered Mental Status: A Unique Neurological Manifestation of Coronavirus Disease 2019. [Abstract]: Like other respiratory viruses, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may enter the central nervous system (CNS) via the hematogenous or neuronal path. Howeve... |
32,697,120 | J Atten Disord | ADHD as a Risk Factor for Infection With Covid-19. | Background: ADHD limits the ability to comply with Covid-19 prevention recommendations. We hypothesized that ADHD constitutes a risk factor for Covid-19 infection and that pharmacotherapy may lower that risk. Methods: Study population included all subjects (N = 14,022) registered with Leumit Health Services between Feb... | adhd;covid-19;prevalence;stimulants | Journal Article | Merzon, Eugene;Manor, Iris;Rotem, Ann;Schneider, Tzipporah;Vinker, Shlomo;Golan Cohen, Avivit;Lauden, Ari;Weizman, Abraham;Green, Ilan | 10.1177/1087054720943271 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: ADHD as a Risk Factor for Infection With Covid-19. [Abstract]: Background: ADHD limits the ability to comply with Covid-19 prevention recommendations. We hypothesized that ADHD constitutes a risk factor for Covid-19 infection and that pharmacotherapy may lower that risk. Methods: Study population included all ... |
32,441,573 | J Aging Soc Policy | COVID-19 and the Future of Long-Term Care: The Urgency of Enhanced Federal Financing. | The economic threat posed by responses to COVID 19 endangers financing for long-term care across the states that is already inadequate and inequitable. Increasing the federal share of Medicaid spending as unemployment rises would mitigate fiscal pressure on states and preserve public services. But unlike the demand for... | aging;fmap;medicaid;dual eligibles;home and community-based care;long-term care;long-term services and supports | Journal Article | Feder, Judy | 10.1080/08959420.2020.1771238 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: COVID-19 and the Future of Long-Term Care: The Urgency of Enhanced Federal Financing. [Abstract]: The economic threat posed by responses to COVID 19 endangers financing for long-term care across the states that is already inadequate and inequitable. Increasing the federal share of Medicaid spending as unemploy... |
32,731,151 | Public Health | Diagnostic value of combined nucleic acid and antibody detection in suspected COVID-19 cases. | OBJECTIVES: Nucleic acid testing is the gold standard method for the diagnosis of coronavirus disease 2019 (COVID-19); however, large numbers of false-negative results have been reported. In this study, nucleic acid detection and antibody detection (IgG and IgM) were combined to improve the testing accuracy of patients... | igg and igm antibody detection;novel coronavirus infection;nucleic acid detection;suspected cases | Journal Article | Zeng, H;Deng, S;Zhou, Z;Qiu, X;Jia, X;Li, Z;Wang, J;Duan, H;Tu, L;Wang, J | 10.1016/j.puhe.2020.07.011 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Diagnostic value of combined nucleic acid and antibody detection in suspected COVID-19 cases. [Abstract]: OBJECTIVES: Nucleic acid testing is the gold standard method for the diagnosis of coronavirus disease 2019 (COVID-19); however, large numbers of false-negative results have been reported. In this study, nu... |
32,396,504 | Emerg Infect Dis | Abdominal Visceral Infarction in 3 Patients with COVID-19. | A high incidence of thrombotic events has been reported in patients with coronavirus disease (COVID-19), which is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. We report 3 clinical cases of patients in Italy with COVID-19 who developed abdominal viscera infarction, demonstrated by co... | 2019 novel coronavirus disease;covid-19;sars-cov-2;abdominal viscera;coronavirus;infarction;respiratory infections;severe acute respiratory syndrome coronavirus 2;viruses;zoonoses | Case Reports;Journal Article | Besutti, Giulia;Bonacini, Riccardo;Iotti, Valentina;Marini, Giulia;Riva, Nicoletta;Dolci, Giovanni;Maiorana, Mariarosa;Spaggiari, Lucia;Monelli, Filippo;Ligabue, Guido;Guaraldi, Giovanni;Rossi, Paolo Giorgi;Pattacini, Pierpaolo;Massari, Marco | 10.3201/eid2608.201161 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Abdominal Visceral Infarction in 3 Patients with COVID-19. [Abstract]: A high incidence of thrombotic events has been reported in patients with coronavirus disease (COVID-19), which is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. We report 3 clinical cases of patients in It... |
32,430,456 | Diabetes Care | Outcomes in Patients With Hyperglycemia Affected by COVID-19: Can We Do More on Glycemic Control? | OBJECTIVE: An important prognostic factor in any form of infection seems to be glucose control in patients with type 2 diabetes. There is no information about the effects of tight glycemic control on coronavirus disease 2019 (COVID-19) outcomes in patients with hyperglycemia. Therefore, we examined the effects of optim... | Journal Article;Research Support, Non-U.S. Gov't | Sardu, Celestino;D'Onofrio, Nunzia;Balestrieri, Maria Luisa;Barbieri, Michelangela;Rizzo, Maria Rosaria;Messina, Vincenzo;Maggi, Paolo;Coppola, Nicola;Paolisso, Giuseppe;Marfella, Raffaele | 10.2337/dc20-0723 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Outcomes in Patients With Hyperglycemia Affected by COVID-19: Can We Do More on Glycemic Control? [Abstract]: OBJECTIVE: An important prognostic factor in any form of infection seems to be glucose control in patients with type 2 diabetes. There is no information about the effects of tight glycemic control on c... | |
33,057,039 | Sci Rep | Coronavirus disease 2019 (COVID-19) in Italy: features on chest computed tomography using a structured report system. | To assess the use of a structured report in the Chest Computed Tomography (CT) reporting of patients with suspicious viral pneumonia by COVID-19 and the evaluation of the main CT patterns. This study included 134 patients (43 women and 91 men; 68.8 years of mean age, range 29-93 years) with suspicious COVID-19 viral in... | Journal Article | Roberto, Grassi;Roberta, Fusco;Paola, Belfiore Maria;Alessandro, Montanelli;Gianluigi, Patelli;Fabrizio, Urraro;Antonella, Petrillo;Vincenza, Granata;Palmino, Sacco;Antonietta, Mazzei Maria;Beatrice, Feragalli;Alfonso, Reginelli;Salvatore, Cappabianca | 10.1038/s41598-020-73788-5 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Coronavirus disease 2019 (COVID-19) in Italy: features on chest computed tomography using a structured report system. [Abstract]: To assess the use of a structured report in the Chest Computed Tomography (CT) reporting of patients with suspicious viral pneumonia by COVID-19 and the evaluation of the main CT pa... | |
32,611,676 | Heart | Treatment with ACE inhibitors or ARBs and risk of severe/lethal COVID-19: a meta-analysis. | OBJECTIVE: It has been hypothesised that the use of ACE inhibitors and angiotensin receptor blockers (ARBs) might either increase or reduce the risk of severe or lethal COVID-19. The findings from the available observational studies varied, and summary estimates are urgently needed to elucidate whether these drugs shou... | cardiac risk factors and prevention;hypertension;meta-analysis | Journal Article;Meta-Analysis | Flacco, Maria Elena;Acuti Martellucci, Cecilia;Bravi, Francesca;Parruti, Giustino;Cappadona, Rosaria;Mascitelli, Alfonso;Manfredini, Roberto;Mantovani, Lorenzo G;Manzoli, Lamberto | 10.1136/heartjnl-2020-317336 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Treatment with ACE inhibitors or ARBs and risk of severe/lethal COVID-19: a meta-analysis. [Abstract]: OBJECTIVE: It has been hypothesised that the use of ACE inhibitors and angiotensin receptor blockers (ARBs) might either increase or reduce the risk of severe or lethal COVID-19. The findings from the availab... |
32,348,594 | Head Neck | Procedural precautions and personal protective equipment during head and neck instrumentation in the COVID-19 era. | BACKGROUND: Otolaryngologists represent a subset of health care workers uniquely vulnerable to COVID-19 transmission. Given the segmentation of extant guidelines concerning precautions and protective equipment for SARS-CoV2, we aimed to provide consolidated recommendations regarding appropriate personal protective equi... | covid-19;high-risk procedures;perioperative protocols;personal protective equipment | Journal Article | Panuganti, Bharat A;Pang, John;Califano, Joseph;Chan, Jason Y K | 10.1002/hed.26220 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Procedural precautions and personal protective equipment during head and neck instrumentation in the COVID-19 era. [Abstract]: BACKGROUND: Otolaryngologists represent a subset of health care workers uniquely vulnerable to COVID-19 transmission. Given the segmentation of extant guidelines concerning precautions... |
32,520,235 | Rev Soc Bras Med Trop | Short-term forecasting of daily COVID-19 cases in Brazil by using the Holt's model. | INTRODUCTION: We evaluated the performance of the Holt's model to forecast the daily COVID-19 reported cases in Brazil and three Brazilian states. METHODS: We chose the date of the first COVID-19 case to April 25, 2020, as the training period, and April 26 to May 3, 2020, as the test period. RESULTS: The Holt's model p... | Journal Article | Martinez, Edson Zangiacomi;Aragon, Davi Casale;Nunes, Altacilio Aparecido | 10.1590/0037-8682-0283-2020 | [
0,
0,
0,
0,
0,
1,
0
] | [Title]: Short-term forecasting of daily COVID-19 cases in Brazil by using the Holt's model. [Abstract]: INTRODUCTION: We evaluated the performance of the Holt's model to forecast the daily COVID-19 reported cases in Brazil and three Brazilian states. METHODS: We chose the date of the first COVID-19 case to April 25, 2... | |
32,232,976 | J Med Virol | CD-sACE2 inclusion compounds: An effective treatment for coronavirus disease 2019 (COVID-19). | Coronaviruses are common human viruses and include the severe acute respiratory syndrome coronavirus (SARS-CoV), the middle east respiratory syndrome coronavirus and the SARS-CoV-2. Coronaviruses mainly bind to transmembrane receptor proteins on the human cell membrane through spike proteins (S-proteins), thus releasin... | 2019-ncov;ace2;covid-19;coronavirus;cyclodextrin | Letter | Sun, Pengfei;Lu, Xiaosheng;Xu, Chao;Wang, Yanjin;Sun, Wenjuan;Xi, Jianing | 10.1002/jmv.25804 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: CD-sACE2 inclusion compounds: An effective treatment for coronavirus disease 2019 (COVID-19). [Abstract]: Coronaviruses are common human viruses and include the severe acute respiratory syndrome coronavirus (SARS-CoV), the middle east respiratory syndrome coronavirus and the SARS-CoV-2. Coronaviruses mainly bi... |
32,972,196 | Antivir Chem Chemother | Clinical evidences on the antiviral properties of macrolide antibiotics in the COVID-19 era and beyond. | Macrolides are a large group of antibiotics characterised by the presence of a macro-lactone ring of variable size. The prototype of macrolide antibiotics, erythromycin was first produced by Streptomyces and associated species more than half a century ago; other related drugs were developed. These drugs have been shown... | macrolides;sars-cov-2;azithromycin;clarithromycin;coronavirus;erythromycin;influenza;respiratory syncytial virus | Journal Article | Poddighe, Dimitri;Aljofan, Mohamad | 10.1177/2040206620961712 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Clinical evidences on the antiviral properties of macrolide antibiotics in the COVID-19 era and beyond. [Abstract]: Macrolides are a large group of antibiotics characterised by the presence of a macro-lactone ring of variable size. The prototype of macrolide antibiotics, erythromycin was first produced by Stre... |
33,014,936 | Front Pediatr | How to Early Identify and Prevent the SARS-CoV-2 Infection in Children for Families? | Importance: COVID-19 has become a worldwide pandemic. Many countries have reported cases of infection in children and newborns, and there is a trend of significantly increasing infections among these populations. Therefore, it is important to provide advice and guidance for the prevention and control of COVID-19 in chi... | covid-19;sars-cov-2;identification;novel coronavirus;pediatrics | Journal Article;Review | Qiao, Meng-Yuan;Chen, Na;Zou, Xian;Mao, Dan-Hua;Cui, Hong-Tao;Li, Wei-Bin;Miao, Jing-Kun;Chen, Qi-Xiong | 10.3389/fped.2020.00542 | [
0,
1,
1,
0,
0,
0,
0
] | [Title]: How to Early Identify and Prevent the SARS-CoV-2 Infection in Children for Families? [Abstract]: Importance: COVID-19 has become a worldwide pandemic. Many countries have reported cases of infection in children and newborns, and there is a trend of significantly increasing infections among these populations. T... |
32,530,822 | Adv Skin Wound Care | Preventing Facial Pressure Injury for Health Care Providers Adhering to COVID-19 Personal Protective Equipment Requirements. | OBJECTIVE: To determine if a repurposed silicone-based dressing used underneath an N95 mask is a safe and beneficial option for facial skin injury prevention without compromising the mask's seal. METHODS: Since February 21, 2020, staff in high-risk areas such as the ED and ICU of King Hamad University Hospital have wor... | Journal Article;Observational Study | Smart, Hiske;Opinion, Francis Byron;Darwich, Issam;Elnawasany, Manal Aly;Kodange, Chaitanya | 10.1097/01.ASW.0000669920.94084.c1 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Preventing Facial Pressure Injury for Health Care Providers Adhering to COVID-19 Personal Protective Equipment Requirements. [Abstract]: OBJECTIVE: To determine if a repurposed silicone-based dressing used underneath an N95 mask is a safe and beneficial option for facial skin injury prevention without compromi... | |
32,985,959 | Popul Health Manag | Disparities in SARS-CoV-2 Positivity Rates: Associations with Race and Ethnicity. | Numerous reports indicate that African Americans and Latinos are being affected disproportionately by coronavirus disease 2019 (COVID-19). Positivity rates have not been analyzed on scale because only 4 states report race/ethnicity as part of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing. Previou... | covid-19;sars-cov-2;ethnicity;race | Journal Article;Research Support, Non-U.S. Gov't | Kaufman, Harvey W;Niles, Justin K;Nash, David B | 10.1089/pop.2020.0163 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Disparities in SARS-CoV-2 Positivity Rates: Associations with Race and Ethnicity. [Abstract]: Numerous reports indicate that African Americans and Latinos are being affected disproportionately by coronavirus disease 2019 (COVID-19). Positivity rates have not been analyzed on scale because only 4 states report ... |
32,588,051 | Int J Epidemiol | Epidemiological and clinical characteristics of 671 COVID-19 patients in Henan Province, China. | BACKGROUND: Despite many reports on the characteristics of coronavirus disease 2019 (COVID-19) in Wuhan, China, relatively little is known about the transmission features of COVID-19 outside Wuhan, especially at the provincial level. METHODS: We collected epidemiological, demographic, clinical, laboratory, radiological... | covid-19;henan province;sars-cov-2 | Journal Article;Research Support, Non-U.S. Gov't | Nie, Yifei;Li, Jitian;Huang, Xueyong;Guo, Wanshen;Zhang, Xiaobai;Ma, Yan;Wang, Haifeng;Qi, Muge;Tang, Xiaoyan;Shen, Xiaojing;Dai, Xiaofeng | 10.1093/ije/dyaa081 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Epidemiological and clinical characteristics of 671 COVID-19 patients in Henan Province, China. [Abstract]: BACKGROUND: Despite many reports on the characteristics of coronavirus disease 2019 (COVID-19) in Wuhan, China, relatively little is known about the transmission features of COVID-19 outside Wuhan, espec... |
32,796,237 | Clin Nucl Med | Reorganization of a Nuclear Medicine Department in Northern Italy During a 2-Month Lockdown for COVID-19 Pandemic. | Coronavirus disease (COVID-19) outbreak has profoundly changed the organization of hospital activities. We present our experience of reorganization of a nuclear medicine service settled in Northern Italy during the pandemic period of March and April 2020 characterized a government-mandated lockdown. Our service remaine... | Journal Article | Maffione, Anna Margherita;Chondrogiannis, Sotirios;Rampin, Lucia;Grassetto, Gaia;Marzola, Maria Cristina;Bassan, Alex;Massaro, Arianna;Colletti, Patrick M;Rubello, Domenico | 10.1097/RLU.0000000000003244 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Reorganization of a Nuclear Medicine Department in Northern Italy During a 2-Month Lockdown for COVID-19 Pandemic. [Abstract]: Coronavirus disease (COVID-19) outbreak has profoundly changed the organization of hospital activities. We present our experience of reorganization of a nuclear medicine service settle... | |
33,065,193 | J Hosp Infect | Incidence and outcomes of healthcare-associated COVID-19 infections: significance of delayed diagnosis and correlation with staff absence. | BACKGROUND: The sudden increase in COVID-19 admissions in hospitals during the SARS-CoV-2 pandemic of 2020 led to onward transmissions among vulnerable inpatients. AIMS: This study was performed to evaluate the prevalence and clinical outcomes of healthcare-associated COVID-19 infections (HA-COVID-19) during the 2020 e... | coronavirus;hcw infections;nosocomial infections | Journal Article | Khonyongwa, K;Taori, S K;Soares, A;Desai, N;Sudhanva, M;Bernal, W;Schelenz, S;Curran, L A | 10.1016/j.jhin.2020.10.006 | [
0,
1,
1,
0,
0,
0,
0
] | [Title]: Incidence and outcomes of healthcare-associated COVID-19 infections: significance of delayed diagnosis and correlation with staff absence. [Abstract]: BACKGROUND: The sudden increase in COVID-19 admissions in hospitals during the SARS-CoV-2 pandemic of 2020 led to onward transmissions among vulnerable inpatien... |
32,298,245 | MMWR Morb Mortal Wkly Rep | Timing of Community Mitigation and Changes in Reported COVID-19 and Community Mobility - Four U.S. Metropolitan Areas, February 26-April 1, 2020. | Community mitigation activities (also referred to as nonpharmaceutical interventions) are actions that persons and communities can take to slow the spread of infectious diseases. Mitigation strategies include personal protective measures (e.g., handwashing, cough etiquette, and face coverings) that persons can use at h... | Journal Article | Lasry, Arielle;Kidder, Daniel;Hast, Marisa;Poovey, Jason;Sunshine, Gregory;Winglee, Kathryn;Zviedrite, Nicole;Ahmed, Faruque;Ethier, Kathleen A | 10.15585/mmwr.mm6915e2 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Timing of Community Mitigation and Changes in Reported COVID-19 and Community Mobility - Four U.S. Metropolitan Areas, February 26-April 1, 2020. [Abstract]: Community mitigation activities (also referred to as nonpharmaceutical interventions) are actions that persons and communities can take to slow the sprea... | |
32,456,489 | Hypertens Pregnancy | Complications and outcomes of SARS-CoV-2 in pregnancy: where and what is the evidence? | OBJECTIVES: To add to the growing evidence on SARS-CoV-2 infection during pregnancy, so as to better inform clinical decision making and optimize patient outcomes. METHODS: A systematic search of relevant databases was perfomed on 25 March 2020 and a repeat search, on 10 April 2020. Reports of pregnant patients with SA... | sars-cov-2;perinatal;pregnancy;vertical transmission | Journal Article;Systematic Review | Teles Abrao Trad, Ayssa;Ibirogba, Eniola R;Elrefaei, Amro;Narang, Kavita;Tonni, Gabriele;Picone, Olivier;Suy, Anna;Carreras Moratonas, Elena;Kilby, Mark D;Ruano, Rodrigo | 10.1080/10641955.2020.1769645 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Complications and outcomes of SARS-CoV-2 in pregnancy: where and what is the evidence? [Abstract]: OBJECTIVES: To add to the growing evidence on SARS-CoV-2 infection during pregnancy, so as to better inform clinical decision making and optimize patient outcomes. METHODS: A systematic search of relevant databas... |
32,685,691 | Glob Health Res Policy | China's model to combat the COVID-19 epidemic: a public health emergency governance approach. | The outbreak of Coronavirus Disease 2019 (COVID-19) is of global health concern. It is a serious public health emergency for the entire world, threatening human life and public health security. To address the epidemic, it is necessary not only to take good prevention and treatment measures, but also to have effective a... | covid-19;china;epidemic;governance model;public health emergency governance | Journal Article | Ning, Yan;Ren, Ran;Nkengurutse, Gerard | 10.1186/s41256-020-00161-4 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: China's model to combat the COVID-19 epidemic: a public health emergency governance approach. [Abstract]: The outbreak of Coronavirus Disease 2019 (COVID-19) is of global health concern. It is a serious public health emergency for the entire world, threatening human life and public health security. To address ... |
32,716,900 | J Med Internet Res | Advance Care Planning Among Users of a Patient Portal During the COVID-19 Pandemic: Retrospective Observational Study. | BACKGROUND: Advance care planning is the process of discussing health care treatment preferences based on patients' personal values, and it often involves the completion of advance directives. In the first months of 2020, a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began circulati... | covid-19;advance care planning;advance directives;electronic health records;health system;pandemic;patient portal;planning;web-based tool | Journal Article;Observational Study;Research Support, N.I.H., Extramural | Portz, Jennifer D;Brungardt, Adreanne;Shanbhag, Prajakta;Staton, Elizabeth W;Bose-Brill, Seuli;Lin, Chen-Tan;Kutner, Jean S;Lum, Hillary D | 10.2196/21385 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Advance Care Planning Among Users of a Patient Portal During the COVID-19 Pandemic: Retrospective Observational Study. [Abstract]: BACKGROUND: Advance care planning is the process of discussing health care treatment preferences based on patients' personal values, and it often involves the completion of advance... |
32,577,525 | Sci Adv | A single dose of ChAdOx1 MERS provides protective immunity in rhesus macaques. | Developing a vaccine to protect against the lethal effects of the many strains of coronavirus is critical given the current global pandemic. For Middle East respiratory syndrome coronavirus (MERS-CoV), we show that rhesus macaques seroconverted rapidly after a single intramuscular vaccination with ChAdOx1 MERS. The vac... | Journal Article;Research Support, N.I.H., Intramural;Research Support, Non-U.S. Gov't | van Doremalen, Neeltje;Haddock, Elaine;Feldmann, Friederike;Meade-White, Kimberly;Bushmaker, Trenton;Fischer, Robert J;Okumura, Atsushi;Hanley, Patrick W;Saturday, Greg;Edwards, Nick J;Clark, Madeleine H A;Lambe, Teresa;Gilbert, Sarah C;Munster, Vincent J | 10.1126/sciadv.aba8399 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: A single dose of ChAdOx1 MERS provides protective immunity in rhesus macaques. [Abstract]: Developing a vaccine to protect against the lethal effects of the many strains of coronavirus is critical given the current global pandemic. For Middle East respiratory syndrome coronavirus (MERS-CoV), we show that rhesu... | |
32,347,201 | Euro Surveill | Clinical characteristics of coronavirus disease (COVID-19) early findings from a teaching hospital in Pavia, North Italy, 21 to 28 February 2020. | We describe clinical characteristics, treatments and outcomes of 44 Caucasian patients with coronavirus disease (COVID-19) at a single hospital in Pavia, Italy, from 21-28 February 2020, at the beginning of the outbreak in Europe. Seventeen patients developed severe disease, two died. After a median of 6 days, 14 patie... | covid-19;ldh;sars-cov-2;retrospective study;severe disease | Journal Article;Comment | Colaneri, Marta;Sacchi, Paolo;Zuccaro, Valentina;Biscarini, Simona;Sachs, Michele;Roda, Silvia;Pieri, Teresa Chiara;Valsecchi, Pietro;Piralla, Antonio;Seminari, Elena;Di Matteo, Angela;Novati, Stefano;Maiocchi, Laura;Pagnucco, Layla;Tirani, Marcello;Baldanti, Fausto;Mojoli, Francesco;Perlini, Stefano;Bruno, Raffaele | 10.2807/1560-7917.ES.2020.25.16.2000460 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Clinical characteristics of coronavirus disease (COVID-19) early findings from a teaching hospital in Pavia, North Italy, 21 to 28 February 2020. [Abstract]: We describe clinical characteristics, treatments and outcomes of 44 Caucasian patients with coronavirus disease (COVID-19) at a single hospital in Pavia,... |
32,612,975 | Front Public Health | COVID-19: An Appeal for an Intersectoral Approach to Tackle With the Emergency. | The knowledge of disease determinants is a pre-requisite for disease prevention. Infectious diseases determinants can be classified in three ways, as: primary or secondary; intrinsic or extrinsic; and associated with host, agent, or environment. In the specific case of COVID-19 several of these determinants are current... | covid-19;sars-cov-2;disease determinants;epidemics;one health;public health;vertebrate hosts | Journal Article | Scagliarini, Alessandra;Alberti, Alberto | 10.3389/fpubh.2020.00302 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: COVID-19: An Appeal for an Intersectoral Approach to Tackle With the Emergency. [Abstract]: The knowledge of disease determinants is a pre-requisite for disease prevention. Infectious diseases determinants can be classified in three ways, as: primary or secondary; intrinsic or extrinsic; and associated with ho... |
32,654,303 | Transpl Infect Dis | COVID-19 in solid organ transplant recipients: Dynamics of disease progression and inflammatory markers in ICU and non-ICU admitted patients. | BACKGROUND: COVID-19 infection varies in severity from minimal symptoms to critical illness associated with a hyperinflammatory response. Data on disease progression in immunosuppressed solid organ transplant (SOT) recipients are limited. METHODS: We examined the electronic medical records of all SOT recipients with CO... | covid-19;cytokines;hospitalization;immunosuppression;inflammation;solid organ transplantation | Comparative Study;Journal Article;Multicenter Study | Roberts, Matthew B;Izzy, Saef;Tahir, Zabreen;Al Jarrah, Ali;Fishman, Jay A;El Khoury, Joseph | 10.1111/tid.13407 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: COVID-19 in solid organ transplant recipients: Dynamics of disease progression and inflammatory markers in ICU and non-ICU admitted patients. [Abstract]: BACKGROUND: COVID-19 infection varies in severity from minimal symptoms to critical illness associated with a hyperinflammatory response. Data on disease pro... |
32,725,744 | Immun Inflamm Dis | SARS-CoV-2 infection associated acute kidney injury in patients with pre-existing chronic renal disease: A report of two cases. | BACKGROUND: The 2019 novel coronavirus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) is driving a novel atypical pneumonia (coronavirus disease 2019 [COVID-19]) outbreak in Wuhan, causing huge public health challenges both in China and globally. Limited data are available for information and prognosis ... | covid-19;sars-cov-2;acute kidney injury;chronic renal disease;coronavirus | Case Reports;Journal Article;Research Support, Non-U.S. Gov't | Wang, Yiru;Lv, Yongman;Liu, Qingquan | 10.1002/iid3.333 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: SARS-CoV-2 infection associated acute kidney injury in patients with pre-existing chronic renal disease: A report of two cases. [Abstract]: BACKGROUND: The 2019 novel coronavirus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) is driving a novel atypical pneumonia (coronavirus disease 2019 [COVI... |
32,899,754 | Molecules | The Potential of Algal Biotechnology to Produce Antiviral Compounds and Biopharmaceuticals. | The emergence of the Coronavirus Disease 2019 (COVID-19) caused by the SARS-CoV-2 virus has led to an unprecedented pandemic, which demands urgent development of antiviral drugs and antibodies; as well as prophylactic approaches, namely vaccines. Algae biotechnology has much to offer in this scenario given the diversit... | covid-19;chlamydomonas reinhardtii;mers-cov;sars-cov-2;monoclonal antibody;recombinant antigen;transplastomic | Journal Article;Review | Rosales-Mendoza, Sergio;Garcia-Silva, Ileana;Gonzalez-Ortega, Omar;Sandoval-Vargas, Jose M;Malla, Ashwini;Vimolmangkang, Sornkanok | 10.3390/molecules25184049 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: The Potential of Algal Biotechnology to Produce Antiviral Compounds and Biopharmaceuticals. [Abstract]: The emergence of the Coronavirus Disease 2019 (COVID-19) caused by the SARS-CoV-2 virus has led to an unprecedented pandemic, which demands urgent development of antiviral drugs and antibodies; as well as pr... |
32,693,646 | Expert Opin Drug Saf | A real-world disproportionality analysis of FDA Adverse Event Reporting System (FAERS) events for baricitinib. | BACKGROUND: Baricitinib is approved for the treatment of rheumatoid arthritis (RA). The authors retrospectively investigated adverse events (AEs) by data-mining a self-reporting database to better understand toxicities, especially since it has been used during the coronavirus disease 2019 (COVID-19) pandemic. METHODS: ... | baricitinib;faers;jak inhibitor;adverse event;pharmacovigilance | Journal Article | Peng, Ling;Xiao, Kui;Ottaviani, Silvia;Stebbing, Justin;Wang, Ying-Jie | 10.1080/14740338.2020.1799975 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: A real-world disproportionality analysis of FDA Adverse Event Reporting System (FAERS) events for baricitinib. [Abstract]: BACKGROUND: Baricitinib is approved for the treatment of rheumatoid arthritis (RA). The authors retrospectively investigated adverse events (AEs) by data-mining a self-reporting database t... |
32,579,455 | Br J Nurs | Burnout: a continuing problem. | Sam Foster, Chief Nurse, Oxford University Hospitals, considers how clinical supervision can be used to support staff during the COVID-19 pandemic to help prevent burnout. | Journal Article | Foster, Sam | 10.12968/bjon.2020.29.12.721 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Burnout: a continuing problem. [Abstract]: Sam Foster, Chief Nurse, Oxford University Hospitals, considers how clinical supervision can be used to support staff during the COVID-19 pandemic to help prevent burnout. [Keywords]: | |
32,075,152 | J Clin Med | Real-Time Estimation of the Risk of Death from Novel Coronavirus (COVID-19) Infection: Inference Using Exported Cases. | The exported cases of 2019 novel coronavirus (COVID-19) infection that were confirmed outside China provide an opportunity to estimate the cumulative incidence and confirmed case fatality risk (cCFR) in mainland China. Knowledge of the cCFR is critical to characterize the severity and understand the pandemic potential ... | censoring;emerging infectious diseases;importation;migration;mortality;travel | Journal Article | Jung, Sung-Mok;Akhmetzhanov, Andrei R;Hayashi, Katsuma;Linton, Natalie M;Yang, Yichi;Yuan, Baoyin;Kobayashi, Tetsuro;Kinoshita, Ryo;Nishiura, Hiroshi | 10.3390/jcm9020523 | [
0,
0,
1,
0,
0,
1,
0
] | [Title]: Real-Time Estimation of the Risk of Death from Novel Coronavirus (COVID-19) Infection: Inference Using Exported Cases. [Abstract]: The exported cases of 2019 novel coronavirus (COVID-19) infection that were confirmed outside China provide an opportunity to estimate the cumulative incidence and confirmed case f... |
32,834,629 | Chaos Solitons Fractals | Global stability and cost-effectiveness analysis of COVID-19 considering the impact of the environment: using data from Ghana. | COVID-19 potentially threatens the lives and livelihood of people all over the world. The disease is presently a major health concern in Ghana and the rest of the world. Although, human to human transmission dynamics has been established, not much research is done on the dynamics of the virus in the environment and the... | covid-19;cost-effectiveness analysis;environmental transmission;global stability;optimal control;sensitivity analysis | Journal Article | Asamoah, Joshua Kiddy K;Owusu, Mark A;Jin, Zhen;Oduro, F T;Abidemi, Afeez;Gyasi, Esther Opoku | 10.1016/j.chaos.2020.110103 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Global stability and cost-effectiveness analysis of COVID-19 considering the impact of the environment: using data from Ghana. [Abstract]: COVID-19 potentially threatens the lives and livelihood of people all over the world. The disease is presently a major health concern in Ghana and the rest of the world. Al... |
32,855,190 | AJNR Am J Neuroradiol | Olfactory Bulb Signal Abnormality in Patients with COVID-19 Who Present with Neurologic Symptoms. | BACKGROUND AND PURPOSE: Unique among the acute neurologic manifestations of Severe Acute Respiratory Syndrome coronavirus 2, the virus responsible for the coronavirus disease 2019 (COVID-19) pandemic, is chemosensory dysfunction (anosmia or dysgeusia), which can be seen in patients who are otherwise oligosymptomatic or... | Journal Article | Strauss, S B;Lantos, J E;Heier, L A;Shatzkes, D R;Phillips, C D | 10.3174/ajnr.A6751 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Olfactory Bulb Signal Abnormality in Patients with COVID-19 Who Present with Neurologic Symptoms. [Abstract]: BACKGROUND AND PURPOSE: Unique among the acute neurologic manifestations of Severe Acute Respiratory Syndrome coronavirus 2, the virus responsible for the coronavirus disease 2019 (COVID-19) pandemic, ... | |
32,920,511 | Biomed Pharmacother | Can a metabolism-targeted therapeutic intervention successfully subjugate SARS-COV-2? A scientific rational. | As a process entailing a high turnover of the host cell molecules, viral replication is required for a successful viral infection and requests virus capacity to acquire the macromolecules required for its propagation. To this end, viruses have adopted several strategies to harness cellular metabolism in accordance with... | cellular metabolism;glycolysis;ppp;sars-cov-2;tca cycle | Journal Article;Review | Mansouri, Kamran;Rastegari-Pouyani, Mohsen;Ghanbri-Movahed, Maryam;Safarzadeh, Mehrnoush;Kiani, Sara;Ghanbari-Movahed, Zahra | 10.1016/j.biopha.2020.110694 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Can a metabolism-targeted therapeutic intervention successfully subjugate SARS-COV-2? A scientific rational. [Abstract]: As a process entailing a high turnover of the host cell molecules, viral replication is required for a successful viral infection and requests virus capacity to acquire the macromolecules re... |
32,292,623 | J Pharm Anal | Recent advances and perspectives of nucleic acid detection for coronavirus. | The recent pneumonia outbreak caused by a novel coronavirus (SARS-CoV-2) is posing a great threat to global public health. Therefore, rapid and accurate identification of pathogenic viruses plays a vital role in selecting appropriate treatments, saving people's lives and preventing epidemics. It is important to establi... | coronavirus;isothermal nucleic acid amplification-based methods;microarray-based methods;nucleic acid detection;pcr-based methods | Journal Article;Review | Shen, Minzhe;Zhou, Ying;Ye, Jiawei;Abdullah Al-Maskri, Abdu Ahmed;Kang, Yu;Zeng, Su;Cai, Sheng | 10.1016/j.jpha.2020.02.010 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Recent advances and perspectives of nucleic acid detection for coronavirus. [Abstract]: The recent pneumonia outbreak caused by a novel coronavirus (SARS-CoV-2) is posing a great threat to global public health. Therefore, rapid and accurate identification of pathogenic viruses plays a vital role in selecting a... |
32,438,617 | J Clin Med | A Continuous Renal Replacement Therapy Protocol for Patients with Acute Kidney Injury in Intensive Care Unit with COVID-19. | COVID-19 often leads to acute respiratory distress syndrome complicated by acute kidney injury (AKI). The indications for renal replacement therapy for these patients are those commonly accepted to treat AKI. We describe a continuous veno-venous haemodialysis (CVVHD) protocol for AKI, which aims to provide the best tre... | aki;ards;crrt;cvvhd;covid-19;hco;cytokines;intensive care | Journal Article | Nalesso, Federico;Garzotto, Francesco;Cattarin, Leda;Gobbi, Laura;Qassim, Laila;Sgarabotto, Luca;Tiberio, Ivo;Calo, Lorenzo A | 10.3390/jcm9051529 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: A Continuous Renal Replacement Therapy Protocol for Patients with Acute Kidney Injury in Intensive Care Unit with COVID-19. [Abstract]: COVID-19 often leads to acute respiratory distress syndrome complicated by acute kidney injury (AKI). The indications for renal replacement therapy for these patients are thos... |
32,374,901 | Kaohsiung J Med Sci | Infection control measures of a Taiwanese hospital to confront the COVID-19 pandemic. | The World Health Organization announced the coronavirus disease 2019 (COVID-19) outbreak a pandemic on 12 March 2020. Although being in proximity to China, the original epicenter of the COVID-19 outbreak, Taiwan has maintained a low number of COVID-19 cases despite its close social ties and heavy traffic between Taiwan... | covid-19;sars-cov-2;taiwan;infection control;novel coronavirus | Journal Article | Chang, Ya-Ting;Lin, Chun-Yu;Tsai, Ming-Ju;Hung, Ching-Tzu;Hsu, Chia-Wen;Lu, Po-Liang;Hou, Ming-Feng | 10.1002/kjm2.12228 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Infection control measures of a Taiwanese hospital to confront the COVID-19 pandemic. [Abstract]: The World Health Organization announced the coronavirus disease 2019 (COVID-19) outbreak a pandemic on 12 March 2020. Although being in proximity to China, the original epicenter of the COVID-19 outbreak, Taiwan h... |
32,271,650 | Telemed J E Health | The Distance Teaching Practice of Combined Mode of Massive Open Online Course Micro-Video for Interns in Emergency Department During the COVID-19 Epidemic Period. | Objective: To observe and analyze the application effect of the combined mode of Massive Open Online Course (MOOC) micro-video during the COVID-19 epidemic period in the distance teaching practice of interns in the emergency department. Materials and Methods: The subjects of this study were 60 trainee nurses who conduc... | covid-19;mooc micro-video;distance teaching;intern;telemedicine | Journal Article | Zhou, Ting;Huang, Sufang;Cheng, Jing;Xiao, Yaru | 10.1089/tmj.2020.0079 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: The Distance Teaching Practice of Combined Mode of Massive Open Online Course Micro-Video for Interns in Emergency Department During the COVID-19 Epidemic Period. [Abstract]: Objective: To observe and analyze the application effect of the combined mode of Massive Open Online Course (MOOC) micro-video during th... |
32,592,845 | Infect Genet Evol | Comparative analysis of protein synthesis rate in COVID-19 with other human coronaviruses. | The genetic code contains information that impacts the efficiency and rate of translation. Translation elongation plays a crucial role in determining the composition of the proteome, errors within a protein contributes towards disease processes. It is important to analyze the novel coronavirus (2019-nCoV) at the codon ... | 2019-ncov;amino acid;covid-19;codon bias;coronavirus;enc;rscu;slow codons | Comparative Study;Journal Article | Dasari, Chandra Mohan;Bhukya, Raju | 10.1016/j.meegid.2020.104432 | [
1,
0,
0,
1,
1,
0,
0
] | [Title]: Comparative analysis of protein synthesis rate in COVID-19 with other human coronaviruses. [Abstract]: The genetic code contains information that impacts the efficiency and rate of translation. Translation elongation plays a crucial role in determining the composition of the proteome, errors within a protein c... |
32,601,651 | Public Health Res Pract | How the COVID-19 pandemic is focusing attention on loneliness and social isolation. | The effects of the coronavirus disease 2019 (COVID-19) pandemic upon human health, economic activity and social engagement have been swift and far reaching. Emerging evidence shows that the pandemic has had dramatic mental health impacts, bringing about increased anxiety and greater social isolation due to the physical... | Journal Article;Review | Smith, Ben J;Lim, Michelle H | 10.17061/phrp3022008 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: How the COVID-19 pandemic is focusing attention on loneliness and social isolation. [Abstract]: The effects of the coronavirus disease 2019 (COVID-19) pandemic upon human health, economic activity and social engagement have been swift and far reaching. Emerging evidence shows that the pandemic has had dramatic... | |
32,361,001 | Microbes Infect | Bioinformatic analysis and identification of single-stranded RNA sequences recognized by TLR7/8 in the SARS-CoV-2, SARS-CoV, and MERS-CoV genomes. | During virus infection, host toll-like receptors (TLRs) can recognize different pathogen-associated molecular patterns and trigger the innate immune response. TLR7/8 can identify the single-stranded RNA (ssRNA) of the virus. This study aimed to search ssRNA sequences recognized by TLR7/8 from the SARS-CoV-2, SARS-CoV, ... | mers;sars;sars-cov-2;tlr7;tlr8 | Journal Article | Moreno-Eutimio, Mario Adan;Lopez-Macias, Constantino;Pastelin-Palacios, Rodolfo | 10.1016/j.micinf.2020.04.009 | [
0,
0,
0,
1,
0,
0,
0
] | [Title]: Bioinformatic analysis and identification of single-stranded RNA sequences recognized by TLR7/8 in the SARS-CoV-2, SARS-CoV, and MERS-CoV genomes. [Abstract]: During virus infection, host toll-like receptors (TLRs) can recognize different pathogen-associated molecular patterns and trigger the innate immune res... |
33,044,171 | Diagn Interv Radiol | A new imaging sign in COVID-19 pneumonia: vascular changes and their correlation with clinical severity of the disease. | PURPOSE: It has come to our attention that specific vascular changes (VCs) appear more frequently in chest computed tomography (CT) of patients with coronavirus disease 2019 (COVID-19). In this study, we aimed to investigate if these specific VCs in chest CT correlate with clinical severity of the disease. METHODS: CT ... | Journal Article | Tekcan Sanli, Deniz Esin;Yildirim, Duzgun | 10.5152/dir.2020.20346 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: A new imaging sign in COVID-19 pneumonia: vascular changes and their correlation with clinical severity of the disease. [Abstract]: PURPOSE: It has come to our attention that specific vascular changes (VCs) appear more frequently in chest computed tomography (CT) of patients with coronavirus disease 2019 (COVI... | |
32,978,237 | Ann Rheum Dis | Preliminary predictive criteria for COVID-19 cytokine storm. | OBJECTIVES: To develop predictive criteria for COVID-19-associated cytokine storm (CS), a severe hyperimmune response that results in organ damage in some patients infected with COVID-19. We hypothesised that criteria for inflammation and cell death would predict this type of CS. METHODS: We analysed 513 hospitalised p... | antirheumatic agents;cytokines;immune system diseases;inflammation | Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't;Review | Caricchio, Roberto;Gallucci, Marcello;Dass, Chandra;Zhang, Xinyan;Gallucci, Stefania;Fleece, David;Bromberg, Michael;Criner, Gerard J | 10.1136/annrheumdis-2020-218323 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Preliminary predictive criteria for COVID-19 cytokine storm. [Abstract]: OBJECTIVES: To develop predictive criteria for COVID-19-associated cytokine storm (CS), a severe hyperimmune response that results in organ damage in some patients infected with COVID-19. We hypothesised that criteria for inflammation and... |
32,838,062 | Clin Epidemiol Glob Health | Impact of Coronavirus disease-19 (COVID-19) lockdown on physical activity and energy expenditure among physiotherapy professionals and students using web-based open E-survey sent through WhatsApp, Facebook and Instagram messengers. | Background: Coronavirus disease - 19 (COVID-19) spread throughout the world and become pandemic. To stop and control the rapid infection of COVID-19 lockdown is the best option. Sudden lockdown implies change in entire lifestyle of the population. Social isolation affects individual's lives by greater reduction in thei... | covid-19;coronavirus;exercise;social isolation;surveys and questionnaires;walking | Journal Article | Srivastav, Adarsh Kumar;Sharma, Neha;Samuel, Asir John | 10.1016/j.cegh.2020.07.003 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Impact of Coronavirus disease-19 (COVID-19) lockdown on physical activity and energy expenditure among physiotherapy professionals and students using web-based open E-survey sent through WhatsApp, Facebook and Instagram messengers. [Abstract]: Background: Coronavirus disease - 19 (COVID-19) spread throughout t... |
32,526,093 | Dermatol Ther | Dermatological therapies with relevance to COVID-19. | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel single-stranded RNA virus that has gripped humanity all over. It affects primarily the respiratory system, but is not limited to it, causing widespread involvement of many organ systems. The cases are still rising at an exponential rate and manifol... | covid-19;sars-cov-2;dermatological therapies;hydroxychloroquine | Journal Article | Shishak, Mansak;Sarkar, Rashmi | 10.1111/dth.13813 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Dermatological therapies with relevance to COVID-19. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel single-stranded RNA virus that has gripped humanity all over. It affects primarily the respiratory system, but is not limited to it, causing widespread involvement of many or... |
32,912,930 | Emerg Med J | Crisis clinical pathway for COVID-19. | The pandemic of COVID-19 has been particularly severe in the New York City area, which has had one of the highest concentrations of cases in the USA. In March 2020, the EDs of New York-Presbyterian Hospital, a 10-hospital health system in the region, began to experience a rapid surge in patients with COVID-19 symptoms.... | disaster planning and response;emergency department operations;epidemiology;guidelines;infectious diseases;major incidents | Editorial | Suh, Edward Hyun;Bodnar, David J;Melville, Laura D;Sharma, Manish;Farmer, Brenna M | 10.1136/emermed-2020-209933 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Crisis clinical pathway for COVID-19. [Abstract]: The pandemic of COVID-19 has been particularly severe in the New York City area, which has had one of the highest concentrations of cases in the USA. In March 2020, the EDs of New York-Presbyterian Hospital, a 10-hospital health system in the region, began to e... |
32,594,577 | J Clin Lab Anal | Heat inactivation of serum interferes with the immunoanalysis of antibodies to SARS-CoV-2. | BACKGROUND: The detection of serum antibodies to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is emerging as a new tool for the coronavirus disease 2019 (COVID-19) diagnosis. Since many coronaviruses are sensitive to heat, heating inactivation of samples at 56 degrees C prior to testing is considere... | covid-19;sars-cov-2;antibodies;heat inactivation;immunoanalysis | Journal Article | Hu, Xiumei;An, Taixue;Situ, Bo;Hu, Yuhai;Ou, Zihao;Li, Qiang;He, Xiaojing;Zhang, Ye;Tian, Peifu;Sun, Dehua;Rui, Yongyu;Wang, Qian;Ding, Dan;Zheng, Lei | 10.1002/jcla.23411 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Heat inactivation of serum interferes with the immunoanalysis of antibodies to SARS-CoV-2. [Abstract]: BACKGROUND: The detection of serum antibodies to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is emerging as a new tool for the coronavirus disease 2019 (COVID-19) diagnosis. Since many co... |
32,742,648 | Ann Med Surg (Lond) | COVID-19 outbreak in Jordan: Epidemiological features, clinical characteristics, and laboratory findings. | Background: In March 2020, an outbreak of coronavirus 19 (COVID-19) was detected in the North of Jordan. This retrospective study is the first from Jordan to report the epidemiologic, clinical, laboratory, and radiologic characteristics of COVID-19 infected patients. Methods: All patients with laboratory-confirmed COVI... | bcg;covid-19;coronavirus;d-dimer;erythrocyte sedimentation rate;jordan;outbreak;sars-cov-2;c-reactive protein | Journal Article | Samrah, Shaher M;Al-Mistarehi, Abdel-Hameed W;Ibnian, Ali M;Raffee, Liqaa A;Momany, Suleiman M;Al-Ali, Musa;Hayajneh, Wail A;Yusef, Dawood H;Awad, Samah M;Khassawneh, Basheer Y | 10.1016/j.amsu.2020.07.020 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: COVID-19 outbreak in Jordan: Epidemiological features, clinical characteristics, and laboratory findings. [Abstract]: Background: In March 2020, an outbreak of coronavirus 19 (COVID-19) was detected in the North of Jordan. This retrospective study is the first from Jordan to report the epidemiologic, clinical,... |
32,383,638 | Emerg Infect Dis | Prolonged Persistence of SARS-CoV-2 RNA in Body Fluids. | We prospectively assessed 49 coronavirus disease cases in Guangdong, China, to estimate the frequency and duration of detectable severe acute respiratory syndrome coronavirus 2 RNA in human body fluids. The prolonged persistence of virus RNA in various body fluids may guide the clinical diagnosis and prevention of onwa... | 2019 novel coronavirus disease;covid-19;china;guangdong;rna;sars-cov-2;coronavirus;coronavirus disease;persistence;respiratory infections;severe acute respiratory syndrome coronavirus 2;viruses;zoonoses | Journal Article;Research Support, Non-U.S. Gov't | Sun, Jiufeng;Xiao, Jianpeng;Sun, Ruilin;Tang, Xi;Liang, Chumin;Lin, Huifang;Zeng, Lilian;Hu, Jianxiong;Yuan, Runyu;Zhou, Pingping;Peng, Jinju;Xiong, Qianlin;Cui, Fengfu;Liu, Zhe;Lu, Jing;Tian, Junzhang;Ma, Wenjun;Ke, Changwen | 10.3201/eid2608.201097 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Prolonged Persistence of SARS-CoV-2 RNA in Body Fluids. [Abstract]: We prospectively assessed 49 coronavirus disease cases in Guangdong, China, to estimate the frequency and duration of detectable severe acute respiratory syndrome coronavirus 2 RNA in human body fluids. The prolonged persistence of virus RNA i... |
32,973,666 | Front Neurol | Acute Ischemic Stroke and COVID-19: Experience From a Comprehensive Stroke Center in Midwest US. | Background: COVID-19 has been associated with increased risk of venous and arterial thromboembolism including ischemic stroke. We report on patients with acute ischemic stroke and concomitant COVID-19 in a diverse patient population. Methods: This is a retrospective analysis of patients hospitalized with acute ischemic... | covid-19;acute ischemic stroke;coronavirus;racial disparity;stroke care | Journal Article | Grewal, Parneet;Pinna, Pranusha;Hall, Julianne P;Dafer, Rima M;Tavarez, Tachira;Pellack, Danielle R;Garg, Rajeev;Osteraas, Nicholas D;Vargas, Alejandro;John, Sayona;Da Silva, Ivan;Conners, James J | 10.3389/fneur.2020.00910 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Acute Ischemic Stroke and COVID-19: Experience From a Comprehensive Stroke Center in Midwest US. [Abstract]: Background: COVID-19 has been associated with increased risk of venous and arterial thromboembolism including ischemic stroke. We report on patients with acute ischemic stroke and concomitant COVID-19 i... |
32,434,805 | Cleve Clin J Med | Perioperative anesthesia care for patients with confirmed or suspected COVID-19. | The operating room environment is very dynamic with many unique challenges for anesthesia teams caring for patients with confirmed or suspected COVID-19. Specific recommendations by national organizations and institution specific step-by-step guidelines and education materials are required to maintain safety for both p... | Journal Article | Mathur, Piyush;Cywinski, Jacek B;Khanna, Sandeep;Trombetta, Carlos | 10.3949/ccjm.87a.ccc035 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Perioperative anesthesia care for patients with confirmed or suspected COVID-19. [Abstract]: The operating room environment is very dynamic with many unique challenges for anesthesia teams caring for patients with confirmed or suspected COVID-19. Specific recommendations by national organizations and instituti... | |
32,836,768 | Contemp Fam Ther | Impact of COVID-19 on the Perinatal Period Through a Biopsychosocial Systemic Framework. | The perinatal period involves major developmental transitions which can be conceptualized through a biopsychosocial (BPS; Engel in Science 196:129-136, 1977, 10.1126/science.847460, in The American Journal of Psychiatry 137:535-544, 1980, 10.1176/ajp.137.5.535), systemic (von Bertalanffy, General system theory: Foundat... | biopsychosocial;covid-19;perinatal;pregnancy;systems | Journal Article | Diamond, Rachel M;Brown, Kristina S;Miranda, Jennifer | 10.1007/s10591-020-09544-8 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Impact of COVID-19 on the Perinatal Period Through a Biopsychosocial Systemic Framework. [Abstract]: The perinatal period involves major developmental transitions which can be conceptualized through a biopsychosocial (BPS; Engel in Science 196:129-136, 1977, 10.1126/science.847460, in The American Journal of P... |
32,748,797 | Emerg Med J | Prone positioning in patients treated with non-invasive ventilation for COVID-19 pneumonia in an Italian emergency department. | We report the experience of prone ventilation in selected patients treated with helmet non-invasive ventilation (NIV) continuous positive airway pressure (CPAP) for acute respiratory failure in COVID-19 pneumonia. Preliminary results showed an improvement in the PaO2 value and PaO2/FiO2 ratio after 1 hour of prone vent... | sars;acute care;infectious diseases;non invasive;pneumonia/infections;respiratory;ventilation;viral | Journal Article | Bastoni, Davide;Poggiali, Erika;Vercelli, Andrea;Demichele, Elena;Tinelli, Valentina;Iannicelli, Teresa;Magnacavallo, Andrea | 10.1136/emermed-2020-209744 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Prone positioning in patients treated with non-invasive ventilation for COVID-19 pneumonia in an Italian emergency department. [Abstract]: We report the experience of prone ventilation in selected patients treated with helmet non-invasive ventilation (NIV) continuous positive airway pressure (CPAP) for acute r... |
32,416,567 | Seizure | Seizures associated with coronavirus infections. | Neurotropic and neuroinvasive capabilities of coronaviruses have been described in humans. Neurological problems found in patients with coronavirus infection include: febrile seizures, convulsions, loss of consciousness, encephalomyelitis, and encephalitis. Coronavirus disease (COVID-19) is caused by SARS-CoV2. In seve... | covid-19;coronavirus;epilepsy;seizure | Journal Article;Review | Asadi-Pooya, Ali A | 10.1016/j.seizure.2020.05.005 | [
1,
0,
1,
0,
0,
0,
0
] | [Title]: Seizures associated with coronavirus infections. [Abstract]: Neurotropic and neuroinvasive capabilities of coronaviruses have been described in humans. Neurological problems found in patients with coronavirus infection include: febrile seizures, convulsions, loss of consciousness, encephalomyelitis, and enceph... |
32,762,171 | Zhejiang Da Xue Xue Bao Yi Xue Ban | [Comparative analysis of structural characteristics and epitopes in S proteins between SARS-CoV-2 and SARS-CoV]. | OBJECTIVE: To provide data support for the study of pathogenic mechanism of SARS-CoV-2 at the molecular level, and provide suitable candidate targets for vaccine, antibody and drug research and development through comparative analysis for structural characteristics and epitopes of S protein of SARS-CoV-2 and SARS-CoV. ... | Comparative Study;Journal Article | Lun, Yongzhi;Liu, Ben;Dong, Wen;Sun, Jie;Pan, Linghong | 10.3785/j.issn.1008-9292.2020.06.06 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: [Comparative analysis of structural characteristics and epitopes in S proteins between SARS-CoV-2 and SARS-CoV]. [Abstract]: OBJECTIVE: To provide data support for the study of pathogenic mechanism of SARS-CoV-2 at the molecular level, and provide suitable candidate targets for vaccine, antibody and drug resea... | |
32,740,720 | Eur Arch Otorhinolaryngol | Tracheostomy, ventilatory wean, and decannulation in COVID-19 patients. | PURPOSE: COVID-19 patients requiring mechanical ventilation can overwhelm existing bed capacity. We aimed to better understand the factors that influence the trajectory of tracheostomy care in this population to facilitate capacity planning and improve outcomes. METHODS: We conducted an observational cohort study of pa... | covid-19;decannulation;peak cough flow;sars-cov-2;tracheostomy;tracheotomy | Journal Article | Tornari, Chrysostomos;Surda, Pavol;Takhar, Arunjit;Amin, Nikul;Dinham, Alison;Harding, Rachel;Ranford, David A;Archer, Sally K;Wyncoll, Duncan;Tricklebank, Stephen;Ahmad, Imran;Simo, Ricard;Arora, Asit | 10.1007/s00405-020-06187-1 | [
1,
0,
1,
0,
0,
0,
0
] | [Title]: Tracheostomy, ventilatory wean, and decannulation in COVID-19 patients. [Abstract]: PURPOSE: COVID-19 patients requiring mechanical ventilation can overwhelm existing bed capacity. We aimed to better understand the factors that influence the trajectory of tracheostomy care in this population to facilitate capa... |
32,393,562 | Ann Fam Med | COVID-19: Notes From the Front Line, Singapore's Primary Health Care Perspective. | Coronavirus disease 2019 (COVID-19) is a rapidly progressing global pandemic against which nations are struggling for containment. Singapore is known to have promptly instituted aggressive public health and containment measures. A key pillar sustaining this is the response of its primary health care network. It is impo... | covid-19;sars-cov-2;coronavirus;pandemic;primary health care;virus | Journal Article | Lim, Wei Han;Wong, Wei Mon | 10.1370/afm.2539 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: COVID-19: Notes From the Front Line, Singapore's Primary Health Care Perspective. [Abstract]: Coronavirus disease 2019 (COVID-19) is a rapidly progressing global pandemic against which nations are struggling for containment. Singapore is known to have promptly instituted aggressive public health and containmen... |
32,265,331 | mBio | Single-Dose, Intranasal Immunization with Recombinant Parainfluenza Virus 5 Expressing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike Protein Protects Mice from Fatal MERS-CoV Infection. | Middle East respiratory syndrome coronavirus (MERS-CoV) can cause severe and fatal acute respiratory disease in humans and remains endemic in the Middle East since first being identified in 2012. There are currently no approved vaccines or therapies available for MERS-CoV. In this study, we evaluated parainfluenza viru... | covid-19;mers;coronavirus;vaccine | Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't | Li, Kun;Li, Zhuo;Wohlford-Lenane, Christine;Meyerholz, David K;Channappanavar, Rudragouda;An, Dong;Perlman, Stanley;McCray, Paul B Jr;He, Biao | 10.1128/mBio.00554-20 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Single-Dose, Intranasal Immunization with Recombinant Parainfluenza Virus 5 Expressing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike Protein Protects Mice from Fatal MERS-CoV Infection. [Abstract]: Middle East respiratory syndrome coronavirus (MERS-CoV) can cause severe and fatal acute respirat... |
33,009,240 | J Chin Med Assoc | A review of severe acute respiratory syndrome coronavirus 2 infection in the reproductive system. | An outbreak of pneumonia associated with coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurred in Wuhan, China, in December 2019, and has been spread worldwide rapidly now. Over 5.3-million confirmed cases and 340,000 disease-associated deaths have been foun... | Journal Article;Review | Huang, Hsin-Hui;Wang, Peng-Hui;Yang, Yi-Ping;Chou, Shih-Jie;Chu, Po-Wei;Wu, Gwo-Jang;Chang, Cheng-Chang | 10.1097/JCMA.0000000000000388 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: A review of severe acute respiratory syndrome coronavirus 2 infection in the reproductive system. [Abstract]: An outbreak of pneumonia associated with coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurred in Wuhan, China, in December 2019, and has b... | |
32,545,224 | Diagnostics (Basel) | Group Testing-Based Robust Algorithm for Diagnosis of COVID-19. | At the time of writing, the COVID-19 infection is spreading rapidly. Currently, there is no vaccine or treatment, and researchers around the world are attempting to fight the infection. In this paper, we consider a diagnosis method for COVID-19, which is characterized by a very rapid rate of infection and is widespread... | covid-19;diagnosis;group testing;posterior probability;robust algorithm | Journal Article | Seong, Jin-Taek | 10.3390/diagnostics10060396 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Group Testing-Based Robust Algorithm for Diagnosis of COVID-19. [Abstract]: At the time of writing, the COVID-19 infection is spreading rapidly. Currently, there is no vaccine or treatment, and researchers around the world are attempting to fight the infection. In this paper, we consider a diagnosis method for... |
32,798,244 | Ultrasound Obstet Gynecol | Anatomical and timely assessment of protein expression of angiotensin-converting enzyme 2, SARS-CoV-2 specific receptor, in fetal and placental tissues: new insight for perinatal counseling. | Infection with SARS-CoV2 does not spare pregnant women and the possibility of vertical transmission which might lead to fetal damages is pending. OBJECTIVE: We hypothesized that the observed low incidence of perinatal infection could be related to a low expression of the membrane receptor for SARS-CoV2, ACE2, in the fe... | ace-2;fetal organs;placenta;protein expression;sars-cov-2;vertical transmission | Journal Article | Faure-Bardon, V;Isnard, P;Roux, N;Leruez-Ville, M;Molina, T;Bessieres, B;Ville, Y | 10.1002/uog.22178 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Anatomical and timely assessment of protein expression of angiotensin-converting enzyme 2, SARS-CoV-2 specific receptor, in fetal and placental tissues: new insight for perinatal counseling. [Abstract]: Infection with SARS-CoV2 does not spare pregnant women and the possibility of vertical transmission which mi... |
32,376,714 | J Clin Pathol | Gene of the month: the 2019-nCoV/SARS-CoV-2 novel coronavirus spike protein. | The year 2020 has seen a major and sustained outbreak of a novel betacoronavirus (severe acute respiratory syndrome (SARS)-coronavirus (CoV)-2) infection that causes fever, severe respiratory illness and pneumonia, a disease called COVID-19. At the time of writing, the death toll was greater than 120 000 worldwide with... | antiviral agents;infections;laboratory infection;virology;viruses | Journal Article;Review | Pillay, Tahir S | 10.1136/jclinpath-2020-206658 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Gene of the month: the 2019-nCoV/SARS-CoV-2 novel coronavirus spike protein. [Abstract]: The year 2020 has seen a major and sustained outbreak of a novel betacoronavirus (severe acute respiratory syndrome (SARS)-coronavirus (CoV)-2) infection that causes fever, severe respiratory illness and pneumonia, a disea... |
32,484,156 | Am J Trop Med Hyg | Why is There Low Morbidity and Mortality of COVID-19 in Africa? | Three months since the detection of the first COVID-19 case in Africa, almost all countries of the continent continued to report lower morbidity and mortality than the global trend, including Europe and North America. We reviewed the merits of various hypotheses advanced to explain this phenomenon, including low seedin... | Journal Article | Njenga, M Kariuki;Dawa, Jeanette;Nanyingi, Mark;Gachohi, John;Ngere, Isaac;Letko, Michael;Otieno, C F;Gunn, Bronwyn M;Osoro, Eric | 10.4269/ajtmh.20-0474 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Why is There Low Morbidity and Mortality of COVID-19 in Africa? [Abstract]: Three months since the detection of the first COVID-19 case in Africa, almost all countries of the continent continued to report lower morbidity and mortality than the global trend, including Europe and North America. We reviewed the m... | |
32,729,549 | Biosens Bioelectron | Diagnostics for SARS-CoV-2 detection: A comprehensive review of the FDA-EUA COVID-19 testing landscape. | The rapidly spreading outbreak of COVID-19 disease is caused by the SARS-CoV-2 virus, first reported in December 2019 in Wuhan, China. As of June 17, 2020, this virus has infected over 8.2 million people but ranges in symptom severity, making it difficult to assess its overall infection rate. There is a need for rapid ... | covid-19;diagnostic testing;fda-eua;immunoassay;point-of-care;rt-pcr;sars-cov-2 | Journal Article;Review | Ravi, Neeraja;Cortade, Dana L;Ng, Elaine;Wang, Shan X | 10.1016/j.bios.2020.112454 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Diagnostics for SARS-CoV-2 detection: A comprehensive review of the FDA-EUA COVID-19 testing landscape. [Abstract]: The rapidly spreading outbreak of COVID-19 disease is caused by the SARS-CoV-2 virus, first reported in December 2019 in Wuhan, China. As of June 17, 2020, this virus has infected over 8.2 millio... |
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