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32,943,416 | AJNR Am J Neuroradiol | COVID-19 Stroke Apical Lung Examination Study: A Diagnostic and Prognostic Imaging Biomarker in Suspected Acute Stroke. | BACKGROUND AND PURPOSE: Diagnosis of coronavirus disease 2019 (COVID-19) relies on clinical features and reverse-transcriptase polymerase chain reaction testing, but the sensitivity is limited. Carotid CTA is a routine acute stroke investigation and includes the lung apices. We evaluated CTA as a potential COVID-19 dia... | Journal Article;Multicenter Study | Siddiqui, J;Bala, F;Sciacca, S;Falzon, A M;Benger, M;Matloob, S A;Miller, F N A C;Simister, R J;Chatterjee, I;Sztriha, L K;Davagnanam, I;Booth, T C | 10.3174/ajnr.A6832 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: COVID-19 Stroke Apical Lung Examination Study: A Diagnostic and Prognostic Imaging Biomarker in Suspected Acute Stroke. [Abstract]: BACKGROUND AND PURPOSE: Diagnosis of coronavirus disease 2019 (COVID-19) relies on clinical features and reverse-transcriptase polymerase chain reaction testing, but the sensitivi... | |
32,267,963 | Anaesthesia | Battling COVID-19: critical care and peri-operative healthcare resource management strategies in a tertiary academic medical centre in Singapore. | In December 2019, a cluster of atypical pneumonia cases were reported in Wuhan, China, and a novel coronavirus elucidated as the aetiologic agent. Although most initial cases occurred in China, the disease, termed coronavirus disease 2019, has become a pandemic and continues to spread rapidly with human-to-human transm... | covid-19;critical care;healthcare;peri-operative;resource management | Journal Article;Review | Lee, C C M;Thampi, S;Lewin, B;Lim, T J D;Rippin, B;Wong, W H;Agrawal, R V | 10.1111/anae.15074 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Battling COVID-19: critical care and peri-operative healthcare resource management strategies in a tertiary academic medical centre in Singapore. [Abstract]: In December 2019, a cluster of atypical pneumonia cases were reported in Wuhan, China, and a novel coronavirus elucidated as the aetiologic agent. Althou... |
32,850,016 | World J Radiol | Convalescent plasma therapy in a pregnant COVID-19 patient with a dramatic clinical and imaging response: A case report. | BACKGROUND: Coronavirus disease 2019 (COVID-19) is a novel very contagious infection which was designated a pandemic in all countries of the world in April 2020. Its presentation varies from mild to severe infection, but the majority of infected patients have mild manifestations. Many therapeutic choices have been sugg... | covid-19;case report;convalescent plasma therapy;favipiravir;pregnancy;radiologic findings | Case Reports | Jafari, Ramezan;Jonaidi-Jafari, Nematollah;Dehghanpoor, Fatemeh;Saburi, Amin | 10.4329/wjr.v12.i7.137 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Convalescent plasma therapy in a pregnant COVID-19 patient with a dramatic clinical and imaging response: A case report. [Abstract]: BACKGROUND: Coronavirus disease 2019 (COVID-19) is a novel very contagious infection which was designated a pandemic in all countries of the world in April 2020. Its presentation... |
32,991,873 | Chest | How We Do It: Operational Recommendations for Scarce Resource Allocation in a Public Health Crisis. | The coronavirus disease 2019 pandemic may require rationing of various medical resources if demand exceeds supply. Theoretical frameworks for resource allocation have provided much needed ethical guidance, but hospitals still need to address objective practicalities and legal vetting to operationalize scarce resource a... | disaster;triage;ventilator | Journal Article | Ehmann, Michael R;Zink, Elizabeth K;Levin, Amanda B;Suarez, Jose I;Belcher, Harolyn M E;Daugherty Biddison, Elizabeth L;Doberman, Danielle J;D'Souza, Karen;Fine, Derek M;Garibaldi, Brian T;Gehrie, Eric A;Golden, Sherita H;Gurses, Ayse P;Hill, Peter M;Hughes, Mark T;Kahn, Jeffrey;Koch, Colleen G;Marx, Jason J;Meisenberg... | 10.1016/j.chest.2020.09.246 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: How We Do It: Operational Recommendations for Scarce Resource Allocation in a Public Health Crisis. [Abstract]: The coronavirus disease 2019 pandemic may require rationing of various medical resources if demand exceeds supply. Theoretical frameworks for resource allocation have provided much needed ethical gui... |
32,800,063 | Dan Med J | Acute loss of smell and taste among patients with symptoms compatible with COVID-19. | INTRODUCTION: The aim of this study was to describe the clinical symptoms, including affection of sense of smell and taste, among participants in a party held in Copenhagen after which many participants reported symptoms compatible with coronavirus disease 2019 (COVID-19). METHODS: A 37-item questionnaire was sent elec... | Journal Article | Bodnia, Nadia Calvo;Katzenstein, Terese L | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Acute loss of smell and taste among patients with symptoms compatible with COVID-19. [Abstract]: INTRODUCTION: The aim of this study was to describe the clinical symptoms, including affection of sense of smell and taste, among participants in a party held in Copenhagen after which many participants reported sy... | ||
32,686,555 | J Telemed Telecare | Scaling virtual health at the epicentre of coronavirus disease 2019: A case study from NYU Langone Health. | The coronavirus disease 2019 (COVID-19) pandemic has accelerated the drive of health-care delivery towards virtual-care platforms. While the potential of virtual care is significant, there are challenges to the implementation and scalability of virtual care as a platform, and health-care organisations are at risk of bu... | covid-19;virtual health;coronavirus;digital health;health services administration;health-care innovations;telemedicine;video visits | Journal Article | Sherwin, Jason;Lawrence, Katharine;Gragnano, Veronica;Testa, Paul A | 10.1177/1357633X20941395 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Scaling virtual health at the epicentre of coronavirus disease 2019: A case study from NYU Langone Health. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic has accelerated the drive of health-care delivery towards virtual-care platforms. While the potential of virtual care is significant, there are... |
32,747,962 | South Med J | Responding to COVID-19: Perspectives on Curricular Changes in a Rural Medical School. | Coronavirus disease 2019 (COVID-19) rapidly led to global human devastation, including multiple deaths, sicknesses, and financial reverberations across many individuals and communities. As COVID-19 gained its foothold in the United States, medical school administrators, faculty, and students had to undergo rapid change... | Journal Article | Crumb, Loni;Campbell, Kendall M;Crowe, Allison;Harris, Janee Avent;Acheampong, Cassandra;Little, Janae | 10.14423/SMJ.0000000000001124 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Responding to COVID-19: Perspectives on Curricular Changes in a Rural Medical School. [Abstract]: Coronavirus disease 2019 (COVID-19) rapidly led to global human devastation, including multiple deaths, sicknesses, and financial reverberations across many individuals and communities. As COVID-19 gained its foot... | |
32,568,009 | J Dermatolog Treat | Clinical management of psoriasis patients during the COVID-19 pandemic. | Psoriasis is a systemic immune-mediated inflammatory disease that requires consistent treatment and follow-up. Given that COVID-19 will persist in the coming years, dermatologists need to adjust their practices accordingly to care for their patients, particularly psoriasis patients managed with systemic therapies. We p... | covid-19;psoriasis;biological products/therapeutic use;biologics;coronavirus;dermatologic agents/therapeutic use;management;pandemic;telemedicine | Letter | Chat, Vipawee S;Uppal, Shelley K;Kearns, Donovan G;Wu, Jashin J | 10.1080/09546634.2020.1781045 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Clinical management of psoriasis patients during the COVID-19 pandemic. [Abstract]: Psoriasis is a systemic immune-mediated inflammatory disease that requires consistent treatment and follow-up. Given that COVID-19 will persist in the coming years, dermatologists need to adjust their practices accordingly to c... |
32,615,326 | Int J Infect Dis | Neurosensory dysfunction: A diagnostic marker of early COVID-19. | OBJECTIVE: To describe neurosensory dysfunctions, including hyposmia, hypogeusia, and tinnitus, in patients with COVID-19. METHODS: Clinical characteristics and oropharyngeal swabs were obtained from 86 patients with COVID-19 hospitalized in Guangzhou Eighth People's Hospital. The chronological analysis method was used... | covid-19;diagnosis;hypogeusia;hyposmia;neurosensory dysfunction | Journal Article | Liang, Yujie;Xu, Jiabin;Chu, Mei;Mai, Jianbo;Lai, Niangmei;Tang, Wen;Yang, Tuanjie;Zhang, Sien;Guan, Chenyu;Zhong, Fan;Yang, Liuping;Liao, Guiqing | 10.1016/j.ijid.2020.06.086 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Neurosensory dysfunction: A diagnostic marker of early COVID-19. [Abstract]: OBJECTIVE: To describe neurosensory dysfunctions, including hyposmia, hypogeusia, and tinnitus, in patients with COVID-19. METHODS: Clinical characteristics and oropharyngeal swabs were obtained from 86 patients with COVID-19 hospital... |
32,658,876 | Recenti Prog Med | [Information technology and digital health to support health in the time of CoViD-19.] | The CoViD-19 pandemic has provided the opportunity for the health care's digital revolution with the unprecedented accelerated expansion of telehealth, telemedicine and other digital health tools. Several tools have been developed and launched at national and international level to face the emergency, including tools t... | Journal Article;Review | Santoro, Eugenio | 10.1701/3407.33919 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: [Information technology and digital health to support health in the time of CoViD-19.] [Abstract]: The CoViD-19 pandemic has provided the opportunity for the health care's digital revolution with the unprecedented accelerated expansion of telehealth, telemedicine and other digital health tools. Several tools h... | |
32,521,619 | Int J Mol Sci | Redox-Modulating Agents in the Treatment of Viral Infections. | Viruses use cell machinery to replicate their genome and produce viral proteins. For this reason, several intracellular factors, including the redox state, might directly or indirectly affect the progression and outcome of viral infection. In physiological conditions, the redox balance between oxidant and antioxidant s... | covid-19;nrf2;antioxidants;influenza;redox state;reduced glutathione (gsh);viral infections | Journal Article;Review | Checconi, Paola;De Angelis, Marta;Marcocci, Maria Elena;Fraternale, Alessandra;Magnani, Mauro;Palamara, Anna Teresa;Nencioni, Lucia | 10.3390/ijms21114084 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Redox-Modulating Agents in the Treatment of Viral Infections. [Abstract]: Viruses use cell machinery to replicate their genome and produce viral proteins. For this reason, several intracellular factors, including the redox state, might directly or indirectly affect the progression and outcome of viral infectio... |
32,838,020 | Inform Med Unlocked | SARS-CoV-2-human protein-protein interaction network. | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the novel coronavirus which caused the coronavirus disease 2019 pandemic and infected more than 12 million victims and resulted in over 560,000 deaths in 213 countries around the world. Having no symptoms in the first week of infection increases the rate o... | covid-19;coronavirus;host-pathogen protein interaction;protein interaction prediction;protein-protein interaction;sars-cov-2 | Journal Article | Khorsand, Babak;Savadi, Abdorreza;Naghibzadeh, Mahmoud | 10.1016/j.imu.2020.100413 | [
0,
0,
0,
1,
0,
0,
0
] | [Title]: SARS-CoV-2-human protein-protein interaction network. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the novel coronavirus which caused the coronavirus disease 2019 pandemic and infected more than 12 million victims and resulted in over 560,000 deaths in 213 countries around the wo... |
32,574,109 | Annu Rev Pharmacol Toxicol | Structural Basis of SARS-CoV-2- and SARS-CoV-Receptor Binding and Small-Molecule Blockers as Potential Therapeutics. | Over the past two decades, deadly coronaviruses, with the most recent being the severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) 2019 pandemic, have majorly challenged public health. The path for virus invasion into humans and other hosts is mediated by host-pathogen interactions, specifically virus... | covid-19;s-glycoprotein;coronavirus;host-pathogen interaction;inhibitors;receptor | Journal Article;Research Support, Non-U.S. Gov't;Review | Sivaraman, Hariharan;Er, Shi Yin;Choong, Yeu Khai;Gavor, Edem;Sivaraman, J | 10.1146/annurev-pharmtox-061220-093932 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Structural Basis of SARS-CoV-2- and SARS-CoV-Receptor Binding and Small-Molecule Blockers as Potential Therapeutics. [Abstract]: Over the past two decades, deadly coronaviruses, with the most recent being the severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) 2019 pandemic, have majorly chall... |
32,379,727 | MMWR Morb Mortal Wkly Rep | Improving Detection and Response to Respiratory Events - Kenya, April 2016-April 2020. | Respiratory pathogens, such as novel influenza A viruses, Middle East respiratory syndrome coronavirus (MERS-CoV), and now, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are of particular concern because of their high transmissibility and history of global spread (1). Clusters of severe respiratory dise... | Journal Article | Idubor, Osatohamwen I;Kobayashi, Miwako;Ndegwa, Linus;Okeyo, Mary;Galgalo, Tura;Kalani, Rosalia;Githii, Susan;Hunsperger, Elizabeth;Balajee, Arunmozhi;Verani, Jennifer R;da Gloria Carvalho, Maria;Winchell, Jonas;Van Beneden, Chris A;Widdowson, Marc-Alain;Makayotto, Lyndah;Chaves, Sandra S | 10.15585/mmwr.mm6918a2 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Improving Detection and Response to Respiratory Events - Kenya, April 2016-April 2020. [Abstract]: Respiratory pathogens, such as novel influenza A viruses, Middle East respiratory syndrome coronavirus (MERS-CoV), and now, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are of particular concern ... | |
32,783,099 | Clin Res Cardiol | COVID-19 among heart transplant recipients in Germany: a multicenter survey. | AIMS: Heart transplantation may represent a particular risk factor for severe coronavirus infectious disease 2019 (COVID-19) due to chronic immunosuppression and frequent comorbidities. We conducted a nation-wide survey of all heart transplant centers in Germany presenting the clinical characteristics of heart transpla... | covid-19;heart transplantation;immunosuppression;mortality | Journal Article;Multicenter Study | Rivinius, Rasmus;Kaya, Ziya;Schramm, Rene;Boeken, Udo;Provaznik, Zdenek;Heim, Christian;Knosalla, Christoph;Schoenrath, Felix;Rieth, Andreas;Berchtold-Herz, Michael;Barten, Markus J;Rauschning, Dominic;Mucke, Victoria T;Heyl, Stephan;Pistulli, Rudin;Grinninger, Carola;Hagl, Christian;Gummert, Jan F;Warnecke, Gregor;Sch... | 10.1007/s00392-020-01722-w | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: COVID-19 among heart transplant recipients in Germany: a multicenter survey. [Abstract]: AIMS: Heart transplantation may represent a particular risk factor for severe coronavirus infectious disease 2019 (COVID-19) due to chronic immunosuppression and frequent comorbidities. We conducted a nation-wide survey of... |
33,075,484 | Indian Pacing Electrophysiol J | Hydroxychloroquine and QTc prolongation in patients with COVID-19: A systematic review and meta-analysis. | BACKGROUND: Among many drugs that hold potential in COVID-19 pandemic, chloroquine (CQ), and its derivative hydroxychloroquine (HCQ) have generated unusual interest. With increasing usage, there has been growing concern about the prolongation of QTc interval and Torsades de Pointes (TdP) with HCQ, especially in combina... | aminoquinoline;covid-19;chloroquine;coronavirus;hydroxychloroquine;qtc prolongation;sars-cov-2;torsades de pointes | Journal Article;Review | Agstam, Sourabh;Yadav, Ashutosh;Kumar-M, Praveen;Gupta, Ankur | 10.1016/j.ipej.2020.10.002 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Hydroxychloroquine and QTc prolongation in patients with COVID-19: A systematic review and meta-analysis. [Abstract]: BACKGROUND: Among many drugs that hold potential in COVID-19 pandemic, chloroquine (CQ), and its derivative hydroxychloroquine (HCQ) have generated unusual interest. With increasing usage, ther... |
32,243,288 | Anesth Analg | COVID-19: Role of Ambulatory Surgery Facilities in This Global Pandemic. | Coronavirus disease 2019 (COVID-19) has now become a global pandemic. This has led the United States to declare a national emergency and resulted in a ban on all elective diagnostic and therapeutic procedures as well as elective surgery in inpatient and outpatient settings. Ambulatory surgery facilities (ASF) that perf... | Journal Article | Rajan, Niraja;Joshi, Girish P | 10.1213/ANE.0000000000004847 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: COVID-19: Role of Ambulatory Surgery Facilities in This Global Pandemic. [Abstract]: Coronavirus disease 2019 (COVID-19) has now become a global pandemic. This has led the United States to declare a national emergency and resulted in a ban on all elective diagnostic and therapeutic procedures as well as electi... | |
32,808,462 | Stem Cells Transl Med | Mesenchymal stromal cells for sepsis and septic shock: Lessons for treatment of COVID-19. | Sepsis is defined as life-threatening organ dysfunction caused by a deregulated immune host response to infection. The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has highlighted this multifactorial and complex syndrome. The absence of specific treatment neither against SARS-CoV-2 nor ... | covid-19;wharton's jelly;acute respiratory distress syndrome;mesenchymal stromal/stem cells;sepsis | Journal Article | Laroye, Caroline;Gibot, Sebastien;Huselstein, Celine;Bensoussan, Daniele | 10.1002/sctm.20-0239 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Mesenchymal stromal cells for sepsis and septic shock: Lessons for treatment of COVID-19. [Abstract]: Sepsis is defined as life-threatening organ dysfunction caused by a deregulated immune host response to infection. The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has highligh... |
32,474,479 | J Xray Sci Technol | Analysis of thin-section CT in patients with coronavirus disease (COVID-19) after hospital discharge. | PURPOSE: To analyze clinical and thin-section computed tomographic (CT) data from the patients with coronavirus disease (COVID-19) to predict the development of pulmonary fibrosis after hospital discharge. MATERIALS AND METHODS: Fifty-nine patients (31 males and 28 females ranging from 25 to 70 years old) with confirme... | covid-19;x-ray computed;coronavirus;severe acute respiratory syndrome;tomography | Journal Article | Wei, Jiangping;Yang, Hong;Lei, Pinggui;Fan, Bing;Qiu, Yingying;Zeng, Bingliang;Yu, Peng;Lv, Jian;Jian, Yinchao;Wan, Chengfeng | 10.3233/XST-200685 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Analysis of thin-section CT in patients with coronavirus disease (COVID-19) after hospital discharge. [Abstract]: PURPOSE: To analyze clinical and thin-section computed tomographic (CT) data from the patients with coronavirus disease (COVID-19) to predict the development of pulmonary fibrosis after hospital di... |
32,619,034 | Cancer Sci | Clinical characteristics of hematological patients concomitant with COVID-19. | The rapid spread of coronavirus disease 2019 (COVID-19) represented the most serious issue to public health globally. Hematological patients as immunocompromised hosts are vulnerable to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. There is little information available regarding the clinical f... | covid-19;sars-cov-2;hematological patient;immunocompromised state | Journal Article | Zhou, Xiaoxi;Wang, Gaoxiang;Chen, Liting;Meng, Fankai;Huang, Liang;Huang, Lifang;Wang, Na;Li, Tongjuan;Cao, Yang;Zhou, Jianfeng | 10.1111/cas.14544 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Clinical characteristics of hematological patients concomitant with COVID-19. [Abstract]: The rapid spread of coronavirus disease 2019 (COVID-19) represented the most serious issue to public health globally. Hematological patients as immunocompromised hosts are vulnerable to severe acute respiratory syndrome c... |
32,837,213 | Prat Anesth Reanim | [Neurological complications of COVID-19]. | Neurological manifestations are likely to be more frequent and complex during COVID-19 than originally anticipated. | covid-19;sars-cov-2 | English Abstract;Journal Article;Review | Flis-Richard, Hugo;Verdonk, Franck | 10.1016/j.pratan.2020.07.008 | [
0,
1,
0,
1,
0,
0,
0
] | [Title]: [Neurological complications of COVID-19]. [Abstract]: Neurological manifestations are likely to be more frequent and complex during COVID-19 than originally anticipated. [Keywords]: covid-19;sars-cov-2 |
32,546,588 | BMJ Glob Health | Rapid urban health security assessment tool: a new resource for evaluating local-level public health preparedness. | Urbanisation will be one of the defining demographic trends of the 21st century-creating unique opportunities for sustainable capacity development, as well as substantial risks and challenges for managing public health and health emergencies. Plans and policies for responding to public health emergencies are generally ... | health policy;health systems;public health | Journal Article;Research Support, Non-U.S. Gov't;Review | Boyce, Matthew R;Katz, Rebecca | 10.1136/bmjgh-2020-002606 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Rapid urban health security assessment tool: a new resource for evaluating local-level public health preparedness. [Abstract]: Urbanisation will be one of the defining demographic trends of the 21st century-creating unique opportunities for sustainable capacity development, as well as substantial risks and cha... |
32,746,750 | Telemed J E Health | Applications of e-Health to Support Person-Centered Health Care at the Time of COVID-19 Pandemic. | Background: Many e-health services were launched after countries relaxed their telehealth regulations to combat the coronavirus disease 2019 (COVID-19) pandemic. e-Health technologies that support person-centered health care are crucial for the patient's needs. In this systematic review, we examined how e-health applic... | coronavirus disease 2019;e-health;medical records;pandemic;person-centered health care;telehealth | Journal Article;Systematic Review | Tebeje, Tsion H;Klein, Jorn | 10.1089/tmj.2020.0201 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Applications of e-Health to Support Person-Centered Health Care at the Time of COVID-19 Pandemic. [Abstract]: Background: Many e-health services were launched after countries relaxed their telehealth regulations to combat the coronavirus disease 2019 (COVID-19) pandemic. e-Health technologies that support pers... |
33,062,530 | Cureus | Pediatric Patients with SARS-CoV-2 Infection: Clinical Characteristics in the United States from a Large Global Health Research Network. | Background Few reports have been published on the clinical presentation of pediatric patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We aim to shed more light on the clinical presentation of pediatric patients infected with coronavirus disease 2019 (COVID-19), and also potential ris... | covid-19;pediatric;sars-cov-2 | Journal Article | Desai, Ankita;Mills, Alexandra;Delozier, Sarah;Cabrera Aviles, Claudia;Edwards, Amy;Dirajlal-Fargo, Sahera;McComsey, Grace | 10.7759/cureus.10413 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Pediatric Patients with SARS-CoV-2 Infection: Clinical Characteristics in the United States from a Large Global Health Research Network. [Abstract]: Background Few reports have been published on the clinical presentation of pediatric patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-... |
32,895,676 | Nat Prod Rep | Challenges and potential for improving the druggability of podophyllotoxin-derived drugs in cancer chemotherapy. | Covering: up to 2020As a main bioactive component of the Chinese, Indian, and American Podophyllum species, the herbal medicine, podophyllotoxin (PTOX) exhibits broad spectrum pharmacological activity, such as superior antitumor activity and against multiple viruses. PTOX derivatives (PTOXs) could arrest the cell cycle... | Journal Article;Research Support, Non-U.S. Gov't | Zhao, Wei;Cong, Ying;Li, Hong-Mei;Li, Shengying;Shen, Yuemao;Qi, Qingsheng;Zhang, Youming;Li, Yue-Zhong;Tang, Ya-Jie | 10.1039/d0np00041h | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Challenges and potential for improving the druggability of podophyllotoxin-derived drugs in cancer chemotherapy. [Abstract]: Covering: up to 2020As a main bioactive component of the Chinese, Indian, and American Podophyllum species, the herbal medicine, podophyllotoxin (PTOX) exhibits broad spectrum pharmacolo... | |
32,444,466 | Cancer Discov | The Landscape of Human Cancer Proteins Targeted by SARS-CoV-2. | The mapping of SARS-CoV-2 human protein-protein interactions by Gordon and colleagues revealed druggable targets that are hijacked by the virus. Here, we highlight several oncogenic pathways identified at the host-virus interface of SARS-CoV-2 to enable cancer biologists to apply their knowledge for rapid drug repurpos... | Journal Article;Review | Tutuncuoglu, Beril;Cakir, Merve;Batra, Jyoti;Bouhaddou, Mehdi;Eckhardt, Manon;Gordon, David E;Krogan, Nevan J | 10.1158/2159-8290.CD-20-0559 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: The Landscape of Human Cancer Proteins Targeted by SARS-CoV-2. [Abstract]: The mapping of SARS-CoV-2 human protein-protein interactions by Gordon and colleagues revealed druggable targets that are hijacked by the virus. Here, we highlight several oncogenic pathways identified at the host-virus interface of SAR... | |
32,400,084 | Am J Transplant | SARS-CoV-2 infection in two patients following recent lung transplantation. | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19) has become a global health problem with pandemic character. Lung transplant recipients may be particularly at risk due to the high degree of immunosuppression and the lung being the organ primarily affected by C... | clinical research/practice;infection and infectious agents - viral;infectious disease;lung disease: infectious;lung transplantation/pulmonology | Case Reports | Koczulla, Rembert A;Sczepanski, Bernd;Koteczki, Adam;Kuhnert, Stefan;Hecker, Matthias;Askevold, Ingolf;Schneider, Christian;Michel, Sebastian;Kneidinger, Nikolaus | 10.1111/ajt.15998 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: SARS-CoV-2 infection in two patients following recent lung transplantation. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19) has become a global health problem with pandemic character. Lung transplant recipients may be particularly at risk... |
32,374,474 | J Cell Mol Med | Natural antiviral compound silvestrol modulates human monocyte-derived macrophages and dendritic cells. | Outbreaks of infections with viruses like Sars-CoV-2, Ebola virus and Zika virus lead to major global health and economic problems because of limited treatment options. Therefore, new antiviral drug candidates are urgently needed. The promising new antiviral drug candidate silvestrol effectively inhibited replication o... | rna viruses;antiviral;cytokines;eif4a;energy metabolism;immune modulation;rocaglate | Journal Article;Research Support, Non-U.S. Gov't | Blum, Leonard;Geisslinger, Gerd;Parnham, Michael J;Grunweller, Arnold;Schiffmann, Susanne | 10.1111/jcmm.15360 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Natural antiviral compound silvestrol modulates human monocyte-derived macrophages and dendritic cells. [Abstract]: Outbreaks of infections with viruses like Sars-CoV-2, Ebola virus and Zika virus lead to major global health and economic problems because of limited treatment options. Therefore, new antiviral d... |
32,654,555 | Hypertension | Clinical Features of COVID-19 in Patients With Essential Hypertension and the Impacts of Renin-angiotensin-aldosterone System Inhibitors on the Prognosis of COVID-19 Patients. | Hypertension is one of the most common comorbidities in patients with coronavirus disease 2019 (COVID-19). This study aimed to clarify the impact of hypertension on COVID-19 and investigate whether the prior use of renin-angiotensin-aldosterone system (RAAS) inhibitors affects the prognosis of COVID-19. A total of 996 ... | comorbidity;coronavirus;mortality;prognosis;risk factor | Journal Article | Pan, Wei;Zhang, Jishou;Wang, Menglong;Ye, Jing;Xu, Yao;Shen, Bo;He, Hua;Wang, Zhen;Ye, Di;Zhao, Mengmeng;Luo, Zhen;Liu, Mingxiao;Zhang, Pingan;Gu, Jian;Liu, Menglin;Li, Dan;Liu, Jianfang;Wan, Jun | 10.1161/HYPERTENSIONAHA.120.15289 | [
1,
1,
0,
1,
0,
0,
0
] | [Title]: Clinical Features of COVID-19 in Patients With Essential Hypertension and the Impacts of Renin-angiotensin-aldosterone System Inhibitors on the Prognosis of COVID-19 Patients. [Abstract]: Hypertension is one of the most common comorbidities in patients with coronavirus disease 2019 (COVID-19). This study aimed... |
32,691,680 | J Biomol Struct Dyn | Cyanobacterial metabolites as promising drug leads against the M(pro) and PL(pro) of SARS-CoV-2: an in silico analysis. | A novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) has emerged as the causative agent behind the coronavirus disease 2019 (COVID-19) pandemic. Treatment efforts have been severely impeded due to the lack of specific effective antiviral drugs for the treatment of COVID-associated pathologies. In the pres... | mm-pbsa;sars-cov-2;cyanobacterial metabolites;deoxycylindrospermopsin;drug-likeness;molecular docking;molecular dynamics simulations | Journal Article | Naidoo, Devashan;Roy, Ayan;Kar, Pallab;Mutanda, Taurai;Anandraj, Akash | 10.1080/07391102.2020.1794972 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Cyanobacterial metabolites as promising drug leads against the M(pro) and PL(pro) of SARS-CoV-2: an in silico analysis. [Abstract]: A novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) has emerged as the causative agent behind the coronavirus disease 2019 (COVID-19) pandemic. Treatment efforts ha... |
33,774,983 | Adv Gerontol | [Older people during the COVID-19 pandemic in the big city: the example of Saint-Petersburg.] | One of the most vulnerable groups during the COVID-19 pandemic was the older people. This is due not only to the danger of the disease itself and its consequences, but also to the conditions of quarantine restrictions. Based on the materials of 26 interviews with representatives of the older people (from 63 to 87 years... | isolation;older people;pandemic;quarantine | Journal Article | Parfenova, O A | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: [Older people during the COVID-19 pandemic in the big city: the example of Saint-Petersburg.] [Abstract]: One of the most vulnerable groups during the COVID-19 pandemic was the older people. This is due not only to the danger of the disease itself and its consequences, but also to the conditions of quarantine ... | |
32,380,368 | Sci Total Environ | Risk of the Brazilian health care system over 5572 municipalities to exceed health care capacity due to the 2019 novel coronavirus (COVID-19). | The spread of the 2019 novel coronavirus (COVID-19) has challenged governments to develop public policies to reduce the load of the COVID-19 on health care systems, which is commonly referred to as "flattening the curve". This study aims to address this issue by proposing a spatial multicriteria approach to estimate th... | covid-19;coronavirus;health care system | Journal Article | Requia, Weeberb J;Kondo, Edson Kenji;Adams, Matthew D;Gold, Diane R;Struchiner, Claudio Jose | 10.1016/j.scitotenv.2020.139144 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Risk of the Brazilian health care system over 5572 municipalities to exceed health care capacity due to the 2019 novel coronavirus (COVID-19). [Abstract]: The spread of the 2019 novel coronavirus (COVID-19) has challenged governments to develop public policies to reduce the load of the COVID-19 on health care ... |
32,281,334 | Zhongguo Zhong Yao Za Zhi | [Strategy of pharmaceutical care services for clinical Chinese pharmacists in coronavirus disease 2019 (COVID-19)]. | The outbreak of coronavirus disease 2019(COVID-19) seriously endangers people's health. Traditional Chinese medicine(TCM) has been recommended for the treatment of COVID-19 in Novel Coronavirus Pneumonia Prevention and Control Strategy, which have made outstanding contributions to the prevention and control of the epid... | 2019-ncov;clinical chinese pharmacist;coronavirus disease 2019(covid-19);pharmaceutical care;phasmaceutical mornitoring;traditional chinese medicine | Journal Article | Lin, Zhi-Jian;Zhang, Bing | 10.19540/j.cnki.cjcmm.20200211.501 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: [Strategy of pharmaceutical care services for clinical Chinese pharmacists in coronavirus disease 2019 (COVID-19)]. [Abstract]: The outbreak of coronavirus disease 2019(COVID-19) seriously endangers people's health. Traditional Chinese medicine(TCM) has been recommended for the treatment of COVID-19 in Novel C... |
32,864,573 | SN Compr Clin Med | Clinical Features of COVID-19 Patients in Xiaogan City. | On February 6, 2020, Xiaogan City became the second most seriously affected city with coronavirus disease 2019 (COVID-19), outside Wuhan district, Hubei Province, China. The objectives are to study the clinical features of COVID-19 patients and assess the relationship between the severity of COVID-19, age, and C-reacti... | c-reactive protein;case series;coronavirus disease 2019 | Journal Article | Feng, Gong;Huang, Wan-Qiang;Liu, Man-Ling;Lin, Si-Ceng;Zhang, Xiao-Zhou;Zhang, Yan;He, Xiao-Qing;Liu, Jun-Lin;Chen, Zi-Jun;Guo, Zi-Kai;Gao, Jie;Yao, Cheng-Zi;He, Na;Yan, Qin-Qin;Mi, Man | 10.1007/s42399-020-00465-z | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: Clinical Features of COVID-19 Patients in Xiaogan City. [Abstract]: On February 6, 2020, Xiaogan City became the second most seriously affected city with coronavirus disease 2019 (COVID-19), outside Wuhan district, Hubei Province, China. The objectives are to study the clinical features of COVID-19 patients an... |
32,686,131 | J Appl Behav Anal | Reducing risky behavior with habit reversal: A review of behavioral strategies to reduce habitual hand-to-head behavior. | Habit reversal training (HRT) has been a mainstay of behavior analysts' repertoire for nearly the last 50 years. HRT has been effective in treating a host of repetitive behavior problems. In the face of the current coronavirus pandemic, HRT has practical public health importance as a possible intervention for reducing ... | covid-19;coronavirus;face-touching;habit reversal | Journal Article;Review | Heinicke, Megan R;Stiede, Jordan T;Miltenberger, Raymond G;Woods, Douglas W | 10.1002/jaba.745 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Reducing risky behavior with habit reversal: A review of behavioral strategies to reduce habitual hand-to-head behavior. [Abstract]: Habit reversal training (HRT) has been a mainstay of behavior analysts' repertoire for nearly the last 50 years. HRT has been effective in treating a host of repetitive behavior ... |
32,390,279 | Dermatol Ther | Cutaneous signs in COVID-19 patients: A review. | Coronavirus disease (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily affects the epithelium of the airways. With the increasing involvement of dermatologist in management of this crisis, cutaneous symptoms gained more and more attention. In this review, we will descri... | covid-19;sars-cov-2;acro-ischemia;androgenetic alopecia;chilblain-like eruptions;maculopapular rash;purpuric rash;urticaria | Journal Article;Review | Wollina, Uwe;Karadag, Ayse Serap;Rowland-Payne, Christopher;Chiriac, Anca;Lotti, Torello | 10.1111/dth.13549 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Cutaneous signs in COVID-19 patients: A review. [Abstract]: Coronavirus disease (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily affects the epithelium of the airways. With the increasing involvement of dermatologist in management of this crisis, cutaneous sy... |
32,961,040 | Stem Cells Transl Med | Viral pandemic preparedness: A pluripotent stem cell-based machine-learning platform for simulating SARS-CoV-2 infection to enable drug discovery and repurposing. | Infection with the SARS-CoV-2 virus has rapidly become a global pandemic for which we were not prepared. Several clinical trials using previously approved drugs and drug combinations are urgently underway to improve our current situation. Unfortunately, a vaccine option is optimistically at least a year away. It is imp... | deepneu;sars-cov-2;antiviral;drug discovery and repurposing;pandemic preparedness;unsupervised learning | Journal Article | Esmail, Sally;Danter, Wayne R | 10.1002/sctm.20-0181 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Viral pandemic preparedness: A pluripotent stem cell-based machine-learning platform for simulating SARS-CoV-2 infection to enable drug discovery and repurposing. [Abstract]: Infection with the SARS-CoV-2 virus has rapidly become a global pandemic for which we were not prepared. Several clinical trials using p... |
32,987,182 | Int J Infect Dis | SARS-COV2 infection in 30 HIV-infected patients followed-up in a French University Hospital. | INTRODUCTION: An acute respiratory disease caused by a novel coronavirus (SARSCOV2) is spreading from China since January 2020. Surprisingly, few cases of Covid-19 have been reported in people living with HIV (PLWHIV). METHODS: Here we present a series of 30 PLWHIV diagnosed for SARS-COV2 infection. The principal outco... | Journal Article | Isernia, Valentina;Julia, Zelie;Le Gac, Sylvie;Bachelard, Antoine;Landman, Roland;Lariven, Sylvie;Joly, Veronique;Deconinck, Laurene;Rioux, Christophe;Lescure, Xavier;Yazdanpanah, Yazdan;Ghosn, Jade | 10.1016/j.ijid.2020.09.1436 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: SARS-COV2 infection in 30 HIV-infected patients followed-up in a French University Hospital. [Abstract]: INTRODUCTION: An acute respiratory disease caused by a novel coronavirus (SARSCOV2) is spreading from China since January 2020. Surprisingly, few cases of Covid-19 have been reported in people living with H... | |
32,680,435 | Ann Otol Rhinol Laryngol | Multidisciplinary Tracheostomy Quality Improvement in the COVID-19 Pandemic: Building a Global Learning Community. | OBJECTIVES: To report experience with a global multidisciplinary tracheostomy e-learning initiative. METHODS: An international multidisciplinary panel of experts convened to build a virtual learning community for tracheostomy care, comprising a web-based platform, five distance learning (interactive webinar) sessions, ... | distance learning;e-learning;medical education;patient safety/quality improvement;tracheostomy;webinar | Journal Article | Swords, Chloe;Bergman, Lina;Wilson-Jeffers, Rachel;Randall, Diane;Morris, Linda L;Brenner, Michael J;Arora, Asit | 10.1177/0003489420941542 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Multidisciplinary Tracheostomy Quality Improvement in the COVID-19 Pandemic: Building a Global Learning Community. [Abstract]: OBJECTIVES: To report experience with a global multidisciplinary tracheostomy e-learning initiative. METHODS: An international multidisciplinary panel of experts convened to build a vi... |
32,586,678 | Radiography (Lond) | Organization of a radiotherapy service during the COVID-19 epidemic: Experience of Regional Center of Oncology of Agadir, Morocco. | This study proposes organization of the activity of a radiotherapy service during the pandemic COVID-19 period. Reliable circuits for staff as well as for patients are installed and treatment protocols are adapted to the current COVID-19 situation. Several scenarios are proposed to deal with any subsequent pandemic sit... | covid-19;management of service;radiotherapy | Journal Article | Amaoui, B;Semghouli, S;Benjaafar, N | 10.1016/j.radi.2020.06.008 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Organization of a radiotherapy service during the COVID-19 epidemic: Experience of Regional Center of Oncology of Agadir, Morocco. [Abstract]: This study proposes organization of the activity of a radiotherapy service during the pandemic COVID-19 period. Reliable circuits for staff as well as for patients are ... |
32,769,322 | Indian J Pathol Microbiol | COVID-19: An up-to-date review - from morphology to pathogenesis. | The entire world is under a devastating pandemic caused by COVID-19 with a high mortality rate. Knowledge of the viral structure, factors that help in its progression and spread, pathological findings, diagnostic methods and, treatment modalities helps in understanding the viral disease and also in treating the patient... | covid-19;rna virus;pandemic;pathology | Journal Article;Review | Bal, Amanjit;Agrawal, Ranjan;Vaideeswar, Pradeep;Arava, Sudheer;Jain, Amita | 10.4103/IJPM.IJPM_779_20 | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: COVID-19: An up-to-date review - from morphology to pathogenesis. [Abstract]: The entire world is under a devastating pandemic caused by COVID-19 with a high mortality rate. Knowledge of the viral structure, factors that help in its progression and spread, pathological findings, diagnostic methods and, treatme... |
32,864,340 | IDCases | Fatal Coronavirus Disease 2019-associated Pulmonary Aspergillosis; A Report of Two Cases and Review of the Literature. | Coronavirus Disease 2019 (COVID-19)-associated pulmonary aspergillosis is an emerging entity. We report two fatal cases of putative COVID-19-associated pulmonary aspergillosis. Both cases were diagnosed on the basis of respiratory tract cultures yielding Aspergillus species and otherwise unexplained clinical and radiol... | covid-19;icu;aspergillosis;viral pneumonia | Case Reports | Abdalla, Shiema;Almaslamani, Muna A;Hashim, Samar M;Ibrahim, Abdulsalam S;Omrani, Ali S | 10.1016/j.idcr.2020.e00935 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Fatal Coronavirus Disease 2019-associated Pulmonary Aspergillosis; A Report of Two Cases and Review of the Literature. [Abstract]: Coronavirus Disease 2019 (COVID-19)-associated pulmonary aspergillosis is an emerging entity. We report two fatal cases of putative COVID-19-associated pulmonary aspergillosis. Bot... |
32,298,748 | J Pain Symptom Manage | Grief During the COVID-19 Pandemic: Considerations for Palliative Care Providers. | The COVID-19 pandemic is anticipated to continue spreading widely across the globe throughout 2020. To mitigate the devastating impact of COVID-19, social distancing and visitor restrictions in health care facilities have been widely implemented. Such policies and practices, along with the direct impact of the spread o... | covid-19;grief;advance care planning;communication;end of life;loss;self-care | Journal Article | Wallace, Cara L;Wladkowski, Stephanie P;Gibson, Allison;White, Patrick | 10.1016/j.jpainsymman.2020.04.012 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Grief During the COVID-19 Pandemic: Considerations for Palliative Care Providers. [Abstract]: The COVID-19 pandemic is anticipated to continue spreading widely across the globe throughout 2020. To mitigate the devastating impact of COVID-19, social distancing and visitor restrictions in health care facilities ... |
32,834,115 | J Mol Struct | Chemical-informatics approach to COVID-19 drug discovery: Exploration of important fragments and data mining based prediction of some hits from natural origins as main protease (Mpro) inhibitors. | As the world struggles against current global pandemic of novel coronavirus disease (COVID-19), it is challenging to trigger drug discovery efforts to search broad-spectrum antiviral agents. Thus, there is a need of strong and sustainable global collaborative works especially in terms of new and existing data analysis ... | covid-19;monte carlo based optimization;natural product;sars-cov mpro;sars-cov-2;spci analysis | Journal Article | Ghosh, Kalyan;Amin, Sk Abdul;Gayen, Shovanlal;Jha, Tarun | 10.1016/j.molstruc.2020.129026 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Chemical-informatics approach to COVID-19 drug discovery: Exploration of important fragments and data mining based prediction of some hits from natural origins as main protease (Mpro) inhibitors. [Abstract]: As the world struggles against current global pandemic of novel coronavirus disease (COVID-19), it is c... |
32,678,049 | Antimicrob Resist Infect Control | Healthcare workers' perspectives on healthcare-associated infections and infection control practices: a video-reflexive ethnography study in the Asir region of Saudi Arabia. | BACKGROUND: Healthcare-associated infections (HAIs) are a global public health problem. For the fulfillment of Saudi Arabia's Vision 2030, the promotion of preventive care medicine through HAI management is a crucial issue. This study explores the perspectives of Saudi tertiary healthcare workers (HCWs) on HAIs and inf... | healthcare worker;healthcare-associated infection;infection control;saudi arabia | Journal Article | Paul, Esther;Alzaydani Asiri, Ibrahim A;Al-Hakami, Ahmed;Chandramoorthy, Harish C;Alshehri, Sarah;Beynon, C M;Alkahtani, Abdullah M;Asiri, Ali H | 10.1186/s13756-020-00756-z | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Healthcare workers' perspectives on healthcare-associated infections and infection control practices: a video-reflexive ethnography study in the Asir region of Saudi Arabia. [Abstract]: BACKGROUND: Healthcare-associated infections (HAIs) are a global public health problem. For the fulfillment of Saudi Arabia's... |
32,892,687 | Platelets | Platelets and renal failure in the SARS-CoV-2 syndrome. | The coronavirus disease 19 (COVID-19) is a highly transmittable viral infection caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 utilizes metallocarboxyl peptidase angiotensin receptor (ACE) 2 to gain entry into human cells. Activation of several proteases facilitates the interacti... | aki;covid-19;d-dimer;sars-cov-2;hypercoagulable;mean platelet volume;renal failure | Journal Article | Taha, Muhanad;Sano, Dahlia;Hanoudi, Samer;Esber, Zahia;Elahi, Morvarid;Gabali, Ali;Chopra, Teena;Draghici, Sorin;Samavati, Lobelia | 10.1080/09537104.2020.1817361 | [
1,
1,
0,
1,
0,
0,
0
] | [Title]: Platelets and renal failure in the SARS-CoV-2 syndrome. [Abstract]: The coronavirus disease 19 (COVID-19) is a highly transmittable viral infection caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 utilizes metallocarboxyl peptidase angiotensin receptor (ACE) 2 to gain entr... |
33,027,870 | Sci Total Environ | The role of computational fluid dynamics tools on investigation of pathogen transmission: Prevention and control. | Transmission mechanics of infectious pathogen in various environments are of great complexity and has always been attracting many researchers' attention. As a cost-effective and powerful method, Computational Fluid Dynamics (CFD) plays an important role in numerically solving environmental fluid mechanics. Besides, wit... | airflow;cfd algorithms;covid-19;epidemic model;pathogen transmission | Journal Article;Review | Peng, Shanbi;Chen, Qikun;Liu, Enbin | 10.1016/j.scitotenv.2020.142090 | [
0,
0,
1,
0,
1,
0,
0
] | [Title]: The role of computational fluid dynamics tools on investigation of pathogen transmission: Prevention and control. [Abstract]: Transmission mechanics of infectious pathogen in various environments are of great complexity and has always been attracting many researchers' attention. As a cost-effective and powerfu... |
32,764,454 | Cancers (Basel) | SARS-CoV-2 Infection and Lung Cancer: Potential Therapeutic Modalities. | Human coronaviruses, especially SARS-CoV-2, are emerging pandemic infectious diseases with high morbidity and mortality in certain group of patients. In general, SARS-CoV-2 causes symptoms ranging from the common cold to severe conditions accompanied by lung injury, acute respiratory distress syndrome in addition to ot... | ace-2;covid-19;coronavirus;sars-cov-2;tmprss2;inhibitors;lung cancer | Journal Article;Review | Gupta, Ishita;Rizeq, Balsam;Elkord, Eyad;Vranic, Semir;Al Moustafa, Ala-Eddin | 10.3390/cancers12082186 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: SARS-CoV-2 Infection and Lung Cancer: Potential Therapeutic Modalities. [Abstract]: Human coronaviruses, especially SARS-CoV-2, are emerging pandemic infectious diseases with high morbidity and mortality in certain group of patients. In general, SARS-CoV-2 causes symptoms ranging from the common cold to severe... |
33,032,616 | Global Health | Lessons learned from COVID-19 for the post-antibiotic future. | INTRODUCTION: COVID-19 has rapidly and radically changed the face of human health and social interaction. As was the case with COVID-19, the world is similarly unprepared to respond to antimicrobial resistance (AMR) and the challenges it will produce. COVID-19 presents an opportunity to examine how the international co... | antimicrobial resistance;covid-19;emergency preparedness;international cooperation | Journal Article | Wilson, Lindsay A;Rogers Van Katwyk, Susan;Fafard, Patrick;Viens, A M;Hoffman, Steven J | 10.1186/s12992-020-00623-x | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Lessons learned from COVID-19 for the post-antibiotic future. [Abstract]: INTRODUCTION: COVID-19 has rapidly and radically changed the face of human health and social interaction. As was the case with COVID-19, the world is similarly unprepared to respond to antimicrobial resistance (AMR) and the challenges it... |
32,971,326 | Eur J Radiol | Chest x-ray in the COVID-19 pandemic: Radiologists' real-world reader performance. | PURPOSE: To report real-world diagnostic performance of chest x-ray (CXR) readings during the COVID-19 pandemic. METHODS: In this retrospective observational study we enrolled all patients presenting to the emergency department of a Milan-based university hospital from February 24th to April 8th 2020 who underwent naso... | covid-19;pneumonia, viral;radiography, thoracic;severe acute respiratory syndrome coronavirus 2 | Journal Article;Observational Study | Cozzi, Andrea;Schiaffino, Simone;Arpaia, Francesco;Della Pepa, Gianmarco;Tritella, Stefania;Bertolotti, Pietro;Menicagli, Laura;Monaco, Cristian Giuseppe;Carbonaro, Luca Alessandro;Spairani, Riccardo;Babaei Paskeh, Bijan;Sardanelli, Francesco | 10.1016/j.ejrad.2020.109272 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Chest x-ray in the COVID-19 pandemic: Radiologists' real-world reader performance. [Abstract]: PURPOSE: To report real-world diagnostic performance of chest x-ray (CXR) readings during the COVID-19 pandemic. METHODS: In this retrospective observational study we enrolled all patients presenting to the emergency... |
32,357,257 | Int Endod J | Role of respirators in controlling the spread of novel coronavirus (COVID-19) amongst dental healthcare providers: a review. | During the ongoing COVID-19 pandemic, healthcare professionals are at the forefront of managing the highly infectious coronavirus. As the most common route of transmission is via aerosols and droplet inhalation, it is critical for healthcare workers to have the correct personal protective equipment (PPE) including gown... | covid-19;masks;pandemic;respirators | Journal Article;Review | Umer, F;Haji, Z;Zafar, K | 10.1111/iej.13313 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Role of respirators in controlling the spread of novel coronavirus (COVID-19) amongst dental healthcare providers: a review. [Abstract]: During the ongoing COVID-19 pandemic, healthcare professionals are at the forefront of managing the highly infectious coronavirus. As the most common route of transmission is... |
32,565,914 | Ther Adv Neurol Disord | Neurological manifestations and implications of COVID-19 pandemic. | The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China and rapidly spread worldwide, with a vast majority of confirmed cases presenting with respiratory symptoms. Potential neurological manifestations and their pathophysiological mechanisms have not been thoroughly established. I... | covid-19;sars-cov-2;cerebrovascular diseases;healthcare impact;neurological manifestations | Journal Article;Review | Tsivgoulis, Georgios;Palaiodimou, Lina;Katsanos, Aristeidis H;Caso, Valeria;Kohrmann, Martin;Molina, Carlos;Cordonnier, Charlotte;Fischer, Urs;Kelly, Peter;Sharma, Vijay K;Chan, Amanda C;Zand, Ramin;Sarraj, Amrou;Schellinger, Peter D;Voumvourakis, Konstantinos I;Grigoriadis, Nikolaos;Alexandrov, Andrei V;Tsiodras, Soti... | 10.1177/1756286420932036 | [
0,
1,
1,
0,
0,
0,
0
] | [Title]: Neurological manifestations and implications of COVID-19 pandemic. [Abstract]: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China and rapidly spread worldwide, with a vast majority of confirmed cases presenting with respiratory symptoms. Potential neurological manife... |
32,032,682 | Microbes Infect | Pathogenicity and transmissibility of 2019-nCoV-A quick overview and comparison with other emerging viruses. | A zoonotic coronavirus, tentatively labeled as 2019-nCoV by the World Health Organization (WHO), has been identified as the causative agent of the viral pneumonia outbreak in Wuhan, China, at the end of 2019. Although 2019-nCoV can cause a severe respiratory illness like SARS and MERS, evidence from clinics suggested t... | ace2;basic reproduction number (r(0));case fatality rate;novel coronavirus infection;sars | Journal Article | Chen, Jieliang | 10.1016/j.micinf.2020.01.004 | [
0,
0,
1,
0,
1,
0,
0
] | [Title]: Pathogenicity and transmissibility of 2019-nCoV-A quick overview and comparison with other emerging viruses. [Abstract]: A zoonotic coronavirus, tentatively labeled as 2019-nCoV by the World Health Organization (WHO), has been identified as the causative agent of the viral pneumonia outbreak in Wuhan, China, a... |
32,340,538 | Otolaryngol Head Neck Surg | Tracheostomy Management during the COVID-19 Pandemic. | The ongoing coronavirus disease 2019 pandemic has led to unprecedented demands on the modern health care system, and the highly contagious nature of the virus has led to particular concerns of infection among health care workers and transmission within health care facilities. While strong data regarding the transmissib... | covid;airway;coronavirus;laryngectomy;safety;tracheostomy | Journal Article;Review | Goldman, Richard A;Swendseid, Brian;Chan, Jason Y K;Lewandowski, Michelle;Adams, Jacqueline;Purcell, Monica;Cognetti, David M | 10.1177/0194599820923632 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Tracheostomy Management during the COVID-19 Pandemic. [Abstract]: The ongoing coronavirus disease 2019 pandemic has led to unprecedented demands on the modern health care system, and the highly contagious nature of the virus has led to particular concerns of infection among health care workers and transmission... |
32,592,975 | Sci Total Environ | Effects of meteorological conditions and air pollution on COVID-19 transmission: Evidence from 219 Chinese cities. | The spatial distribution of the COVID-19 infection in China cannot be explained solely by geographical distance and regulatory stringency. In this research we investigate how meteorological conditions and air pollution, as concurring factors, impact COVID-19 transmission, using data on new confirmed cases from 219 pref... | air pollution;ambient temperature;covid-19;china;relative humidity;wind speed | Journal Article | Zhang, Zhenbo;Xue, Ting;Jin, Xiaoyu | 10.1016/j.scitotenv.2020.140244 | [
0,
0,
1,
0,
1,
0,
0
] | [Title]: Effects of meteorological conditions and air pollution on COVID-19 transmission: Evidence from 219 Chinese cities. [Abstract]: The spatial distribution of the COVID-19 infection in China cannot be explained solely by geographical distance and regulatory stringency. In this research we investigate how meteorolo... |
33,024,280 | Nat Hum Behav | State-level needs for social distancing and contact tracing to contain COVID-19 in the United States. | Starting in mid-May 2020, many US states began relaxing social-distancing measures that were put in place to mitigate the spread of COVID-19. To evaluate the impact of relaxation of restrictions on COVID-19 dynamics and control, we developed a transmission dynamic model and calibrated it to US state-level COVID-19 case... | Journal Article;Research Support, N.I.H., Extramural;Research Support, U.S. Gov't, Non-P.H.S. | Chiu, Weihsueh A;Fischer, Rebecca;Ndeffo-Mbah, Martial L | 10.1038/s41562-020-00969-7 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: State-level needs for social distancing and contact tracing to contain COVID-19 in the United States. [Abstract]: Starting in mid-May 2020, many US states began relaxing social-distancing measures that were put in place to mitigate the spread of COVID-19. To evaluate the impact of relaxation of restrictions on... | |
32,289,260 | J Obstet Gynecol Neonatal Nurs | Using the Coronavirus Pandemic as an Opportunity to Address the Use of Human Milk and Breastfeeding as Lifesaving Medical Interventions. | Health care providers should use this current pandemic as an opportunity educate the public about the importance of human milk and breastfeeding as lifesaving medical interventions. | Editorial | Spatz, Diane L | 10.1016/j.jogn.2020.03.002 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Using the Coronavirus Pandemic as an Opportunity to Address the Use of Human Milk and Breastfeeding as Lifesaving Medical Interventions. [Abstract]: Health care providers should use this current pandemic as an opportunity educate the public about the importance of human milk and breastfeeding as lifesaving med... | |
32,802,896 | J Immunol Res | The Application of Single-Cell RNA Sequencing in Vaccinology. | Single-cell RNA sequencing allows highly detailed profiling of cellular immune responses from limited-volume samples, advancing prospects of a new era of systems immunology. The power of single-cell RNA sequencing offers various opportunities to decipher the immune response to infectious diseases and vaccines. Here, we... | Journal Article;Review | Noe, Andres;Cargill, Tamsin N;Nielsen, Carolyn M;Russell, Andrew J C;Barnes, Eleanor | 10.1155/2020/8624963 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: The Application of Single-Cell RNA Sequencing in Vaccinology. [Abstract]: Single-cell RNA sequencing allows highly detailed profiling of cellular immune responses from limited-volume samples, advancing prospects of a new era of systems immunology. The power of single-cell RNA sequencing offers various opportun... | |
32,779,446 | Cell J | IBD Patients Could Be Silent Carriers for Novel Coronavirus and Less Prone to its Severe Adverse Events: True or False? | Inflammatory bowel diseases (IBDs) are chronic disorders of the gastrointestinal tract. The goal of IBD treatment is to reduce the inflammation period and induce long-term remission. Use of anti-inflammatory drugs including corticosteroids, immunosuppressants and biologicals, is often the first step in the treatment of... | anti-tnf-alpha;covid-19;crohn's disease;ibd;ulcerative colitis | Journal Article | Baradaran Ghavami, S Haghayegh;Shahrokh, S Habnam;Hossein-Khannazer, Nikoo;Shpichka, Anastasia;Asadzadeh Aghdaei, Hamid;Timashev, Peter;Vosough, Massoud | 10.22074/cellj.2020.7603 | [
1,
0,
1,
0,
0,
0,
0
] | [Title]: IBD Patients Could Be Silent Carriers for Novel Coronavirus and Less Prone to its Severe Adverse Events: True or False? [Abstract]: Inflammatory bowel diseases (IBDs) are chronic disorders of the gastrointestinal tract. The goal of IBD treatment is to reduce the inflammation period and induce long-term remissi... |
32,666,088 | Am J Crit Care | Rapid Critical Care Training of Nurses in the Surge Response to the Coronavirus Pandemic. | BACKGROUND: In response to the coronavirus pandemic, New York State mandated that all hospitals double the capacity of their adult intensive care units In this facility, resources were mobilized to increase from 104 to 283 beds. OBJECTIVE: To create and implement a 3-hour curriculum to prepare several hundred non-criti... | Journal Article | Brickman, Diana;Greenway, Andrew;Sobocinski, Kathryn;Thai, Hanh;Turick, Ashley;Xuereb, Kevin;Zambardino, Danielle;Barie, Philip S;Liu, Susan I | 10.4037/ajcc2020142 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Rapid Critical Care Training of Nurses in the Surge Response to the Coronavirus Pandemic. [Abstract]: BACKGROUND: In response to the coronavirus pandemic, New York State mandated that all hospitals double the capacity of their adult intensive care units In this facility, resources were mobilized to increase fr... | |
32,492,212 | J Med Virol | Retest positive for SARS-CoV-2 RNA of "recovered" patients with COVID-19: Persistence, sampling issues, or re-infection? | Retest Positive for severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) from "recovered" coronavirus disease-19 (COVID-19) has been reported and raised several important questions for this novel coronavirus and COVID-19 disease. In this commentary, we discussed several questions: (a) Can SARS-CoV-2 re-... | sars coronavirus < virus classification;coronavirus < virus classification;disease control;immunity/immunization < epidemiology;persistent infection < infection | Journal Article | Kang, Hanyujie;Wang, Yishan;Tong, Zhaohui;Liu, Xuefeng | 10.1002/jmv.26114 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Retest positive for SARS-CoV-2 RNA of "recovered" patients with COVID-19: Persistence, sampling issues, or re-infection? [Abstract]: Retest Positive for severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) from "recovered" coronavirus disease-19 (COVID-19) has been reported and raised several i... |
33,041,119 | Am J Emerg Med | Guillain-Barre syndrome in a patient previously diagnosed with COVID-19. | As the COVID-19 pandemic continues to progress, the medical community is rapidly trying to identify complications and patterns of disease to improve patient outcomes. In a recent systematic review, it has been reported that isolated cases of Guillain-Barre Syndrome (GBS) have occurred secondary to COVID-19 infection. G... | Journal Article | Defabio, Alexandria C;Scott, Thomas R;Stenberg, Robert T;Simon, Erin L | 10.1016/j.ajem.2020.07.074 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Guillain-Barre syndrome in a patient previously diagnosed with COVID-19. [Abstract]: As the COVID-19 pandemic continues to progress, the medical community is rapidly trying to identify complications and patterns of disease to improve patient outcomes. In a recent systematic review, it has been reported that is... | |
32,474,557 | Indian J Med Res | An overview of mobile applications (apps) to support the coronavirus disease 2019 response in India. | Background & objectives: The potential benefits of mobile health (mHealth) initiatives to manage the coronavirus disease 2019 (COVID-19) pandemic have been explored. The Government of India, State governments, and healthcare organizations have developed various mobile apps for the containment of COVID-19. This study wa... | contact tracing - covid-19 - india - mobile apps - mobile health - privacy - telemedicine | Journal Article;Systematic Review | Bassi, Abhinav;Arfin, Sumaiya;John, Oommen;Jha, Vivekanand | 10.4103/ijmr.IJMR_1200_20 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: An overview of mobile applications (apps) to support the coronavirus disease 2019 response in India. [Abstract]: Background & objectives: The potential benefits of mobile health (mHealth) initiatives to manage the coronavirus disease 2019 (COVID-19) pandemic have been explored. The Government of India, State g... |
32,838,022 | Model Earth Syst Environ | Spatial prediction of COVID-19 epidemic using ARIMA techniques in India. | The latest Coronavirus (COVID-19) has become an infectious disease that causes millions of people to infect. Effective short-term prediction models are designed to estimate the number of possible events. The data obtained from 30th January to 26 April, 2020 and from 27th April 2020 to 11th May 2020 as modelling and for... | arima;covid-19;disease forecasting;spatio-temporal analysis;weighted overlay | Journal Article | Roy, Santanu;Bhunia, Gouri Sankar;Shit, Pravat Kumar | 10.1007/s40808-020-00890-y | [
0,
0,
1,
0,
0,
1,
0
] | [Title]: Spatial prediction of COVID-19 epidemic using ARIMA techniques in India. [Abstract]: The latest Coronavirus (COVID-19) has become an infectious disease that causes millions of people to infect. Effective short-term prediction models are designed to estimate the number of possible events. The data obtained from... |
32,346,676 | Nat Cancer | Crowdsourcing a crisis response for COVID-19 in oncology. | Crowdsourcing efforts are currently underway to collect and analyze data from patients with cancer who are affected by the COVID-19 pandemic. These community-led initiatives will fill key knowledge gaps to tackle crucial clinical questions on the complexities of infection with the causative coronavirus SARS-Cov-2 in th... | cancer;sars-cov-2;scientific community | Journal Article | Desai, Aakash;Warner, Jeremy;Kuderer, Nicole;Thompson, Mike;Painter, Corrie;Lyman, Gary;Lopes, Gilberto | 10.1038/s43018-020-0065-z | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Crowdsourcing a crisis response for COVID-19 in oncology. [Abstract]: Crowdsourcing efforts are currently underway to collect and analyze data from patients with cancer who are affected by the COVID-19 pandemic. These community-led initiatives will fill key knowledge gaps to tackle crucial clinical questions o... |
32,989,999 | Bratisl Lek Listy | Analysis of general surgery outpatient clinic admissions and operations during COVID-19 pandemic in Turkey: Reactions of 12728 patients. | Covid-19 pandemic is spreading rapidly in Turkey. We aimed to examine the numbers and demographic data of patients who applied to the general surgery outpatient clinics and operated in this process. Our primary outcome is to reveal the response of general surgery patients to the Covid-19 pandemic.The first Covid-19 cas... | Journal Article | Ferahman, S;Dural, A C;Aydin, H;Sahbaz, N A;Akarsu, C;Peker, K D;Donmez, T;Karabulut, M | 10.4149/BLL_2020_086 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Analysis of general surgery outpatient clinic admissions and operations during COVID-19 pandemic in Turkey: Reactions of 12728 patients. [Abstract]: Covid-19 pandemic is spreading rapidly in Turkey. We aimed to examine the numbers and demographic data of patients who applied to the general surgery outpatient c... | |
32,910,979 | Clin Chim Acta | Performance of an automated chemiluminescence SARS-CoV-2 IG-G assay. | INTRODUCTION: We describe our evaluation of the Abbott SARS-CoV-2 IgG assay on the Architect immunoassay analyser. METHODS: We assessed assay precision, sensitivity, specificity, positive/negative predictive values (PPV/NPV), cross-reactivity (influenza/dengue/hepatitis B and C/rheumatoid factor/anti-nuclear/double-str... | antibodies;assay evaluation;reactivity index;sars-cov-2 | Journal Article | Lau, C S;Oh, H M L;Hoo, S P;Liang, Y L;Phua, S K;Aw, T C | 10.1016/j.cca.2020.09.005 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Performance of an automated chemiluminescence SARS-CoV-2 IG-G assay. [Abstract]: INTRODUCTION: We describe our evaluation of the Abbott SARS-CoV-2 IgG assay on the Architect immunoassay analyser. METHODS: We assessed assay precision, sensitivity, specificity, positive/negative predictive values (PPV/NPV), cros... |
32,961,074 | Open Biol | Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines. | Coronavirus disease 2019 (COVID-19) has swept the world, unlike any other pandemic in the last 50 years. Our understanding of the disease has evolved rapidly since the outbreak; disease prognosis is influenced mainly by multi-organ involvement. Acute respiratory distress syndrome, heart failure, renal failure, liver da... | covid-19;ifn-gamma;il-6;sars;tnf-alpha;coronavirus | Journal Article;Review | Fara, Antonella;Mitrev, Zan;Rosalia, Rodney Alexander;Assas, Bakri M | 10.1098/rsob.200160 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines. [Abstract]: Coronavirus disease 2019 (COVID-19) has swept the world, unlike any other pandemic in the last 50 years. Our understanding of the disease has evolved rapidly since the outbreak; disease prognosis is influenced mainly by multi-o... |
32,673,759 | J Am Coll Surg | The American College of Surgeons Responds to COVID-19. | The COVID-19 pandemic abruptly, and perhaps irrevocably, changed the way we live, conduct our business affairs, and practice medicine and surgery. In mid-March 2020, as COVID-19 infections escalated exponentially across many areas of the US, the Centers for Disease Control (CDC), the Surgeon General, and the American C... | Journal Article;Research Support, N.I.H., Extramural;Review | Rusch, Valerie W;Wexner, Steven D | 10.1016/j.jamcollsurg.2020.06.020 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: The American College of Surgeons Responds to COVID-19. [Abstract]: The COVID-19 pandemic abruptly, and perhaps irrevocably, changed the way we live, conduct our business affairs, and practice medicine and surgery. In mid-March 2020, as COVID-19 infections escalated exponentially across many areas of the US, th... | |
32,311,034 | J Am Med Inform Assoc | Telehealth transformation: COVID-19 and the rise of virtual care. | The novel coronavirus disease-19 (COVID-19) pandemic has altered our economy, society, and healthcare system. While this crisis has presented the U.S. healthcare delivery system with unprecedented challenges, the pandemic has catalyzed rapid adoption of telehealth, or the entire spectrum of activities used to deliver c... | covid;pandemic;telehealth;telemedicine | Journal Article | Wosik, Jedrek;Fudim, Marat;Cameron, Blake;Gellad, Ziad F;Cho, Alex;Phinney, Donna;Curtis, Simon;Roman, Matthew;Poon, Eric G;Ferranti, Jeffrey;Katz, Jason N;Tcheng, James | 10.1093/jamia/ocaa067 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Telehealth transformation: COVID-19 and the rise of virtual care. [Abstract]: The novel coronavirus disease-19 (COVID-19) pandemic has altered our economy, society, and healthcare system. While this crisis has presented the U.S. healthcare delivery system with unprecedented challenges, the pandemic has catalyz... |
32,087,334 | Microbes Infect | The epidemic of 2019-novel-coronavirus (2019-nCoV) pneumonia and insights for emerging infectious diseases in the future. | At the end of December 2019, a novel coronavirus, 2019-nCoV, caused an outbreak of pneumonia spreading from Wuhan, Hubei province, to the whole country of China, which has posed great threats to public health and attracted enormous attention around the world. To date, there are no clinically approved vaccines or antivi... | 2019-ncov;ace2;bat;pneumonia;sars-cov;spike | Journal Article;Research Support, Non-U.S. Gov't;Review | Li, Jin-Yan;You, Zhi;Wang, Qiong;Zhou, Zhi-Jian;Qiu, Ye;Luo, Rui;Ge, Xing-Yi | 10.1016/j.micinf.2020.02.002 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: The epidemic of 2019-novel-coronavirus (2019-nCoV) pneumonia and insights for emerging infectious diseases in the future. [Abstract]: At the end of December 2019, a novel coronavirus, 2019-nCoV, caused an outbreak of pneumonia spreading from Wuhan, Hubei province, to the whole country of China, which has posed... |
32,685,437 | ERJ Open Res | Proning reduces ventilation heterogeneity in patients with elevated BMI: implications for COVID-19 pneumonia management? | Simulations of patient-based lungs suggest that proning reduces ventilation heterogeneity in overweight and obese subjects but increases heterogeneity in non-overweight subjects. This suggests proning may be beneficial for overweight #COVID19 patients. https://bit.ly/2MfCiyk. | Journal Article | Foy, Brody H;Brightling, Christopher E;Siddiqui, Salman | 10.1183/23120541.00292-2020 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Proning reduces ventilation heterogeneity in patients with elevated BMI: implications for COVID-19 pneumonia management? [Abstract]: Simulations of patient-based lungs suggest that proning reduces ventilation heterogeneity in overweight and obese subjects but increases heterogeneity in non-overweight subjects.... | |
32,369,611 | Anaesthesia | Management of the airway and lung isolation for thoracic surgery during the COVID-19 pandemic: Recommendations for clinical practice endorsed by the Association for Cardiothoracic Anaesthesia and Critical Care and the Society for Cardiothoracic Surgery in Great Britain and Ireland. | Intra-operative aerosol-generating procedures are arguably unavoidable in the routine provision of thoracic anaesthesia. Airway management for such patients during the COVID-19 pandemic including tracheal intubation, lung isolation, one-lung ventilation and flexible bronchoscopy may pose a significant risk to healthcar... | covid-19;airway;anaesthesia;coronavirus;double-lumen tube placement;lung isolation;thoracic surgery | Journal Article;Review | Thornton, M;Reid, D;Shelley, B;Steven, M | 10.1111/anae.15112 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Management of the airway and lung isolation for thoracic surgery during the COVID-19 pandemic: Recommendations for clinical practice endorsed by the Association for Cardiothoracic Anaesthesia and Critical Care and the Society for Cardiothoracic Surgery in Great Britain and Ireland. [Abstract]: Intra-operative ... |
32,662,949 | ESC Heart Fail | Modulation of the acute defence reaction by eplerenone prevents cardiac disease progression in viral myocarditis. | AIMS: Left ventricular (LV) dysfunction in viral myocarditis is attributed to myocardial inflammation and fibrosis, inducing acute and long-time cardiac damage. Interventions are not established. On the basis of the link between inflammation, fibrosis, aldosterone, and extracellular matrix regulation, we aimed to inves... | covid-19;coxsackievirus b3;fibrosis;inflammation;mineralocorticoid receptor inhibition;myocarditis | Journal Article;Research Support, Non-U.S. Gov't | Tschope, Carsten;Van Linthout, Sophie;Jager, Sebastian;Arndt, Robert;Trippel, Tobias;Muller, Irene;Elsanhoury, Ahmed;Rutschow, Susanne;Anker, Stefan D;Schultheiss, Heinz-Peter;Pauschinger, Matthias;Spillmann, Frank;Pappritz, Kathleen | 10.1002/ehf2.12887 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Modulation of the acute defence reaction by eplerenone prevents cardiac disease progression in viral myocarditis. [Abstract]: AIMS: Left ventricular (LV) dysfunction in viral myocarditis is attributed to myocardial inflammation and fibrosis, inducing acute and long-time cardiac damage. Interventions are not es... |
32,342,138 | Knee Surg Sports Traumatol Arthrosc | COVID-19 coronavirus: recommended personal protective equipment for the orthopaedic and trauma surgeon. | PURPOSE: With the COVID-19 crisis, recommendations for personal protective equipment (PPE) are necessary for protection in orthopaedics and traumatology. The primary purpose of this study is to review and present current evidence and recommendations for personal protective equipment and safety recommendations for ortho... | aerosols;covid-19;corona;helmet;masks;personal protective equipment;protection;respirator masks;suits;surgeon | Journal Article;Review | Hirschmann, Michael T;Hart, Alister;Henckel, Johann;Sadoghi, Patrick;Seil, Romain;Mouton, Caroline | 10.1007/s00167-020-06022-4 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: COVID-19 coronavirus: recommended personal protective equipment for the orthopaedic and trauma surgeon. [Abstract]: PURPOSE: With the COVID-19 crisis, recommendations for personal protective equipment (PPE) are necessary for protection in orthopaedics and traumatology. The primary purpose of this study is to r... |
33,069,564 | Arch Pediatr | Fulminant hepatic failure: A rare and devastating manifestation of Coronavirus disease 2019 in an 11-year-old boy. | Although several typical manifestation of novel coronavirus disease 2019 (COVID-19) including respiratory symptoms, weakness, fever, and fatigue have been reported, some rare and novel manifestations have also been observed, particularly in children. We report a pediatric case of fulminant hepatic failure associated wi... | fulminant hepatic failure;novel coronavirus disease 2019;sars-cov-2;transplant | Case Reports;Journal Article | Haji Esmaeil Memar, E;Mamishi, S;Sharifzadeh Ekbatani, M;Alimadadi, H;Yaghmaei, B;Chegini, V;Janani, S;Mahmoudi, S | 10.1016/j.arcped.2020.09.009 | [
0,
0,
0,
0,
0,
0,
1
] | [Title]: Fulminant hepatic failure: A rare and devastating manifestation of Coronavirus disease 2019 in an 11-year-old boy. [Abstract]: Although several typical manifestation of novel coronavirus disease 2019 (COVID-19) including respiratory symptoms, weakness, fever, and fatigue have been reported, some rare and novel... |
32,576,310 | Disaster Med Public Health Prep | Face Masks for All and All for Face Masks in the COVID-19 Pandemic: Community Level Production to Face the Global Shortage and Shorten the Epidemic. | The current coronavirus disease 2019 (COVID-19) pandemic caused a global shortage of medical masks, leaving most exposed health personnel without appropriate protection.Since the beginning of the outbreak, the World Health Organization WHO) has revised several times the recommendations on general use of facemasks. Unti... | covid-19;homemade masks;medical masks;pandemic prevention;personal protection equipment | Journal Article | Missoni, Eduardo;Armocida, Benedetta;Formenti, Beatrice | 10.1017/dmp.2020.207 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Face Masks for All and All for Face Masks in the COVID-19 Pandemic: Community Level Production to Face the Global Shortage and Shorten the Epidemic. [Abstract]: The current coronavirus disease 2019 (COVID-19) pandemic caused a global shortage of medical masks, leaving most exposed health personnel without appr... |
32,391,997 | Ned Tijdschr Geneeskd | [The first 100 COVID-19 patients admitted to the Elisabeth-Tweesteden Hospital, Tilburg, The Netherlands]. | Here we describe the characteristics of the first 100 laboratory confirmed COVID-19 patients admitted to the Elisabeth-Tweesteden Hospital (Tilburg, The Netherlands). The median age was 72 years, 67% was male, approximately 80% had co-morbidity, approximately 50% of which consisted of hypertension, cardiac and or pulmo... | Journal Article | Murk, Jean-Luc;van de Biggelaar, Rik;Stohr, Joep;Verweij, Jaco;Buiting, Anton;Wittens, Sabine;van Hooft, Martijn;Diederen, Bram;Kluiters-de Hingh, Yvette;Ranschaer, Erik;Brouwer, Annemarie;Retera, Jeroen;Verheijen, Margot;Ramnarain, Dharmanand;van Ek, Ivo;van Oers, Jos | [
1,
1,
0,
0,
0,
0,
0
] | [Title]: [The first 100 COVID-19 patients admitted to the Elisabeth-Tweesteden Hospital, Tilburg, The Netherlands]. [Abstract]: Here we describe the characteristics of the first 100 laboratory confirmed COVID-19 patients admitted to the Elisabeth-Tweesteden Hospital (Tilburg, The Netherlands). The median age was 72 yea... | ||
32,423,250 | Eur J Prev Cardiol | Effect of coronavirus infection on the human heart: A scoping review. | BACKGROUND: The global coronavirus disease 2019 pandemic has highlighted the importance of understanding the cardiovascular implications of coronavirus infections, with more severe disease in those with cardiovascular co-morbidities, and resulting cardiac manifestations such as myocardial injury, arrhythmias, and heart... | coronavirus;middle east respiratory syndrome;cardiovascular system;common cold;coronavirus disease 2019;heart;severe acute respiratory syndrome | Journal Article;Systematic Review | Ho, Jamie Sy;Tambyah, Paul A;Ho, Andrew Fw;Chan, Mark Yy;Sia, Ching-Hui | 10.1177/2047487320925965 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Effect of coronavirus infection on the human heart: A scoping review. [Abstract]: BACKGROUND: The global coronavirus disease 2019 pandemic has highlighted the importance of understanding the cardiovascular implications of coronavirus infections, with more severe disease in those with cardiovascular co-morbidit... |
32,788,834 | Saudi Pharm J | The renin angiotensin aldosterone system and COVID-19. | The ongoing pandemic has stimulated study of the Renin Angiotensin Aldosterone System (RAAS), and how it can be manipulated to treat COVID-19. Studies are examining whether drugs that act on the RAAS system might be useful to treat COVID-19. COVID-19 and the RAAS are closely linked both in infection and in possible pos... | angiotensin;covid-19;raas | Journal Article;Review | Alsufyani, Hadeel A;Docherty, James R | 10.1016/j.jsps.2020.06.019 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: The renin angiotensin aldosterone system and COVID-19. [Abstract]: The ongoing pandemic has stimulated study of the Renin Angiotensin Aldosterone System (RAAS), and how it can be manipulated to treat COVID-19. Studies are examining whether drugs that act on the RAAS system might be useful to treat COVID-19. CO... |
32,603,679 | Braz J Infect Dis | Calcineurin inhibitors revisited: A new paradigm for COVID-19? | The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) can cause mild, moderate or severe disease (COVID-19). In severe disease, there is hyperinflammation causing severe symptoms. Severe COVID-19 is an immunological phenomenon, rather than a direct viral damage disease. Therapies for COVID-19 are all investi... | ards;cytokine storm;hyperinflammation;transplantation | Journal Article | Hage, Rene;Steinack, Carolin;Schuurmans, Mace M | 10.1016/j.bjid.2020.06.005 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Calcineurin inhibitors revisited: A new paradigm for COVID-19? [Abstract]: The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) can cause mild, moderate or severe disease (COVID-19). In severe disease, there is hyperinflammation causing severe symptoms. Severe COVID-19 is an immunological phenomeno... |
32,569,013 | J Cardiovasc Pharmacol | Current Perspectives of Anticoagulation in Patients With COVID-19. | Thromboembolism and myocardial injury is common in patients with COVID-19. Low-molecular-weight heparin appears to be associated with a good prognosis in patients with COVID-19 and has the ability to reduce coagulation and inflammation markers. Hospitalized patients with COVID-19 should be placed on thromboprophylaxis ... | Journal Article;Review | Gavioli, Elizabeth M;Sikorska, Gabriela;Man, Ammy;Rana, Jay;Vider, Etty | 10.1097/FJC.0000000000000861 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Current Perspectives of Anticoagulation in Patients With COVID-19. [Abstract]: Thromboembolism and myocardial injury is common in patients with COVID-19. Low-molecular-weight heparin appears to be associated with a good prognosis in patients with COVID-19 and has the ability to reduce coagulation and inflammat... | |
32,434,108 | Eur J Cancer | Cancer treatment during the coronavirus disease 2019 pandemic: Do not postpone, do it! | At the end of January 2020, a novel betacoronavirus, known as severe acute respiratory syndrome coronavirus 2, progressively spread in Italy. Patients with cancer are considered more prone to infections because of the immunosuppressive status due to both malignancy and anticancer treatments. From the first Italian gove... | covid-19;cancer care;pandemic;practical health vigilance recommendations;sars-cov-2 | Journal Article | Omarini, Claudia;Maur, Michela;Luppi, Gabriele;Narni, Franco;Luppi, Mario;Dominici, Massimo;Longo, Giuseppe;Piacentini, Federico | 10.1016/j.ejca.2020.04.034 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Cancer treatment during the coronavirus disease 2019 pandemic: Do not postpone, do it! [Abstract]: At the end of January 2020, a novel betacoronavirus, known as severe acute respiratory syndrome coronavirus 2, progressively spread in Italy. Patients with cancer are considered more prone to infections because o... |
32,888,767 | Hum Immunol | Conserved HLA binding peptides from five non-structural proteins of SARS-CoV-2-An in silico glance. | Coronavirus Disease 2019 (COVID-19) is a dangerous global threat that has no clinically approved treatment yet. Bioinformatics represent an outstanding approach to reveal key immunogenic regions in viral proteins. Here, five severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural proteins (NSPs) (NS... | covid-19;epitopes;in silico;mers;non-structural proteins;sars | Journal Article | Marchan, Jose | 10.1016/j.humimm.2020.08.001 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Conserved HLA binding peptides from five non-structural proteins of SARS-CoV-2-An in silico glance. [Abstract]: Coronavirus Disease 2019 (COVID-19) is a dangerous global threat that has no clinically approved treatment yet. Bioinformatics represent an outstanding approach to reveal key immunogenic regions in v... |
32,834,835 | J Funct Foods | Phytochemicals containing biologically active polyphenols as an effective agent against Covid-19-inducing coronavirus. | The outbreak of Covid-19 disease caused by SARS-CoV-19, along with the lack of targeted medicaments and vaccines, forced the scientific world to search for new antiviral formulations. In this review, we describe the current knowledge about plant extracts containing polyphenols that inhibit Covid-19. Many plant-derived ... | 3clpro, 3c-like protease;ace2, angiotensin-converting enzyme 2;antiviral;bioactivity;cbe, cbm, herbal extracts from rhizoma cibotii;cc50, 50% cytotoxicity concentration;cdc, cholesterol-dependent cytolysin;cpe, cytopathogenic effect;cth, herbal extract from cassiae semen;coronavirus;covid-19, coronavirus disease 2019;d... | Journal Article;Review | Chojnacka, K;Witek-Krowiak, A;Skrzypczak, D;Mikula, K;Mlynarz, P | 10.1016/j.jff.2020.104146 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Phytochemicals containing biologically active polyphenols as an effective agent against Covid-19-inducing coronavirus. [Abstract]: The outbreak of Covid-19 disease caused by SARS-CoV-19, along with the lack of targeted medicaments and vaccines, forced the scientific world to search for new antiviral formulatio... |
33,063,823 | Clin Sci (Lond) | Twenty years of progress in angiotensin converting enzyme 2 and its link to SARS-CoV-2 disease. | The virulence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the aggressive nature of the disease has transformed the universal pace of research in the desperate attempt to seek effective therapies to halt the morbidity and mortality of this pandemic. The rapid sequencing of the SARS-... | angiotensin ii;angiotensin-(1-7);cardiovascular disease;chymase;coronavirus;innate immunity | Journal Article;Research Support, N.I.H., Extramural;Review | Ferrario, Carlos M;Ahmad, Sarfaraz;Groban, Leanne | 10.1042/CS20200901 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Twenty years of progress in angiotensin converting enzyme 2 and its link to SARS-CoV-2 disease. [Abstract]: The virulence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the aggressive nature of the disease has transformed the universal pace of research in the desperate attemp... |
32,534,109 | Hellenic J Cardiol | Involvement of cardiovascular system as the critical point in coronavirus disease 2019 (COVID-19) prognosis and recovery. | The novel coronavirus disease 2019 (COVID-19) pandemic has already caused more than 300,000 deaths worldwide. Several studies have elucidated the central role of cardiovascular complications in the disease course. Herein, we provide a concise review of current knowledge regarding the involvement of cardiovascular syste... | covid-19;cardiovascular comorbidities;cardiovascular complications;pandemic;sars-cov-2 | Journal Article;Review | Lazaridis, Charalampos;Vlachogiannis, Nikolaos I;Bakogiannis, Constantinos;Spyridopoulos, Ioakim;Stamatelopoulos, Kimon;Kanakakis, Ioannis;Vassilikos, Vassilios;Stellos, Konstantinos | 10.1016/j.hjc.2020.05.004 | [
1,
1,
0,
1,
0,
0,
0
] | [Title]: Involvement of cardiovascular system as the critical point in coronavirus disease 2019 (COVID-19) prognosis and recovery. [Abstract]: The novel coronavirus disease 2019 (COVID-19) pandemic has already caused more than 300,000 deaths worldwide. Several studies have elucidated the central role of cardiovascular ... |
32,443,202 | Environ Pollut | Disinfection technology of hospital wastes and wastewater: Suggestions for disinfection strategy during coronavirus Disease 2019 (COVID-19) pandemic in China. | Hospitals are important sources of pollutants resulted from diagnostic, laboratory and research activities as well as medicine excretion by patients, which include active component of drugs and metabolite, chemicals, residues of pharmaceuticals, radioactive markers, iodinated contrast media, etc. The discharge of hospi... | coronavirus disease 2019 (covid-19);disinfection;hospital;wastes;wastewater | Journal Article;Review | Wang, Jiao;Shen, Jin;Ye, Dan;Yan, Xu;Zhang, Yujing;Yang, Wenjing;Li, Xinwu;Wang, Junqi;Zhang, Liubo;Pan, Lijun | 10.1016/j.envpol.2020.114665 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Disinfection technology of hospital wastes and wastewater: Suggestions for disinfection strategy during coronavirus Disease 2019 (COVID-19) pandemic in China. [Abstract]: Hospitals are important sources of pollutants resulted from diagnostic, laboratory and research activities as well as medicine excretion by ... |
32,329,102 | Immunol Rev | Application of a portable instrument for rapid and reliable detection of SARS-CoV-2 infection in any environment. | The ongoing outbreak of the novel coronavirus (SARS-CoV-2) infection is creating serious challenges for health laboratories that seek to identify viral infections as early as possible, optimally at the earliest appearance of symptom. Indeed, there is urgent need to develop and deploy robust diagnostic methodologies not... | sars-cov-2 detection;coronavirus;device;instrument;portable | Journal Article | Martinelli, Federico;Perrone, Anna;Della Noce, Isabella;Colombo, Lorenzo;Lo Priore, Stefano;Romano, Simone | 10.1111/imr.12857 | [
0,
1,
0,
0,
0,
0,
0
] | [Title]: Application of a portable instrument for rapid and reliable detection of SARS-CoV-2 infection in any environment. [Abstract]: The ongoing outbreak of the novel coronavirus (SARS-CoV-2) infection is creating serious challenges for health laboratories that seek to identify viral infections as early as possible, ... |
32,633,929 | A A Pract | Aerosol Box 2.0: Adjustments and Improvements Made in Mexico for Intubating Patients During the Coronavirus Disease 2019 Pandemic. | In January 2020, a global pandemic was declared by the World Health Organization authorities for coronavirus disease 2019 (COVID-19). Since then, we have looked for ways to avoid transmission with mitigation measures and social distancing. However, areas with a high incidence of COVID-19 have struggled to maintain adeq... | Journal Article | Lopez Hernandez, Mercedes Nicte;Alvarez Resendiz, Gerardo Esteban;Galvan Talamantes, Yazmin;Lagarda Cuevas, Juan;Wilson-Manriquez, Eduardo A;Calva Ruiz, Diana Stephanie;Ham Armenta, Cristian Irvin | 10.1213/XAA.0000000000001273 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Aerosol Box 2.0: Adjustments and Improvements Made in Mexico for Intubating Patients During the Coronavirus Disease 2019 Pandemic. [Abstract]: In January 2020, a global pandemic was declared by the World Health Organization authorities for coronavirus disease 2019 (COVID-19). Since then, we have looked for way... | |
33,074,996 | Curr Opin Gastroenterol | Tracking COVID-19 via sewage. | PURPOSE OF REVIEW: We discuss the potential role of the faecal chain in COVID-19 and highlight recent studies using waste water-based epidemiology (WBE) to track severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). RECENT FINDINGS: WBE has been suggested as an adjunct to improve disease surveillance and aid ea... | Journal Article;Review | Rooney, Christopher M;Moura, Ines B;Wilcox, Mark H | 10.1097/MOG.0000000000000692 | [
0,
1,
1,
0,
0,
0,
0
] | [Title]: Tracking COVID-19 via sewage. [Abstract]: PURPOSE OF REVIEW: We discuss the potential role of the faecal chain in COVID-19 and highlight recent studies using waste water-based epidemiology (WBE) to track severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). RECENT FINDINGS: WBE has been suggested as an... | |
32,513,292 | Implement Sci | Implementation science in times of Covid-19. | The emergence of SARS-CoV-2/Covid-19 affects all of us and is associated with rapid and massive changes in healthcare and societies. As a response, a range of interventions for patients and populations have been implemented in health and preventive settings, or need to be implemented in the short and long term. Impleme... | Editorial;Research Support, Non-U.S. Gov't | Wensing, Michel;Sales, Anne;Armstrong, Rebecca;Wilson, Paul | 10.1186/s13012-020-01006-x | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Implementation science in times of Covid-19. [Abstract]: The emergence of SARS-CoV-2/Covid-19 affects all of us and is associated with rapid and massive changes in healthcare and societies. As a response, a range of interventions for patients and populations have been implemented in health and preventive setti... | |
32,934,372 | Nat Med | Convalescent plasma treatment of severe COVID-19: a propensity score-matched control study. | Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a new human disease with few effective treatments(1). Convalescent plasma, donated by persons who have recovered from COVID-19, is the acellular component of blood that contains antibodies, including those th... | Journal Article;Research Support, Non-U.S. Gov't | Liu, Sean T H;Lin, Hung-Mo;Baine, Ian;Wajnberg, Ania;Gumprecht, Jeffrey P;Rahman, Farah;Rodriguez, Denise;Tandon, Pranai;Bassily-Marcus, Adel;Bander, Jeffrey;Sanky, Charles;Dupper, Amy;Zheng, Allen;Nguyen, Freddy T;Amanat, Fatima;Stadlbauer, Daniel;Altman, Deena R;Chen, Benjamin K;Krammer, Florian;Mendu, Damodara Rao;F... | 10.1038/s41591-020-1088-9 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Convalescent plasma treatment of severe COVID-19: a propensity score-matched control study. [Abstract]: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a new human disease with few effective treatments(1). Convalescent plasma, donated by persons w... | |
32,471,930 | Reg Anesth Pain Med | Reconfiguring the scope and practice of regional anesthesia in a pandemic: the COVID-19 perspective. | The COVID-19 outbreak is on the world. While many countries have imposed general lockdown, emergency services are continuing. Healthcare professionals have been infected with the virulent severe acute respiratory syndrome coronavirus-2 (SARS), which spreads by close contact and aerosols. The anesthesiologist is particu... | education;epidemiology;obstetrics;postoperative complications;regional anesthesia | Journal Article;Review | Ashokka, Balakrishnan;Chakraborty, Arunangshu;Subramanian, Balavenkat J;Karmakar, Manoj Kumar;Chan, Vincent | 10.1136/rapm-2020-101541 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: Reconfiguring the scope and practice of regional anesthesia in a pandemic: the COVID-19 perspective. [Abstract]: The COVID-19 outbreak is on the world. While many countries have imposed general lockdown, emergency services are continuing. Healthcare professionals have been infected with the virulent severe acu... |
32,804,048 | Telemed J E Health | COVID-19 Brings About Rapid Changes in the Telehealth Landscape. | Telehealth is still an evolving tool with many practitioners noting that barriers such as reimbursement and liability issues exist, preventing its regular use. This commentary addresses the many legislative changes that have taken place during the coronavirus (COVID-19) pandemic. First, we provide a brief overview of c... | e-health;telehealth;telemedicine;telenursing | Journal Article | Moore, Miranda A;Munroe, Dominique D | 10.1089/tmj.2020.0228 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: COVID-19 Brings About Rapid Changes in the Telehealth Landscape. [Abstract]: Telehealth is still an evolving tool with many practitioners noting that barriers such as reimbursement and liability issues exist, preventing its regular use. This commentary addresses the many legislative changes that have taken pla... |
32,572,532 | Intensive Care Med | Review of influenza-associated pulmonary aspergillosis in ICU patients and proposal for a case definition: an expert opinion. | PURPOSE: Invasive pulmonary aspergillosis is increasingly reported in patients with influenza admitted to the intensive care unit (ICU). Classification of patients with influenza-associated pulmonary aspergillosis (IAPA) using the current definitions for invasive fungal diseases has proven difficult, and our aim was to... | covid-19;icu;influenza;invasive aspergillosis;viral pneumonia | Consensus Development Conference;Journal Article | Verweij, Paul E;Rijnders, Bart J A;Bruggemann, Roger J M;Azoulay, Elie;Bassetti, Matteo;Blot, Stijn;Calandra, Thierry;Clancy, Cornelius J;Cornely, Oliver A;Chiller, Tom;Depuydt, Pieter;Giacobbe, Daniele Roberto;Janssen, Nico A F;Kullberg, Bart-Jan;Lagrou, Katrien;Lass-Florl, Cornelia;Lewis, Russell E;Liu, Peter Wei-Lun... | 10.1007/s00134-020-06091-6 | [
1,
1,
0,
1,
0,
0,
0
] | [Title]: Review of influenza-associated pulmonary aspergillosis in ICU patients and proposal for a case definition: an expert opinion. [Abstract]: PURPOSE: Invasive pulmonary aspergillosis is increasingly reported in patients with influenza admitted to the intensive care unit (ICU). Classification of patients with infl... |
32,873,147 | Scott Med J | Angiotensin converting enzyme inhibitors do not increase the risk of poor outcomes in COVID-19 disease. A multi-centre observational study. | BACKGROUND AND AIMS: Hypertension is associated with an increased risk of severe outcomes with COVID-19 disease. Angiotensin Converting Enzyme (ACE) inhibitors are widely used as a first line medication for the treatment of hypertension in the UK, although their use was suggested in early reports to increase the risk a... | hypertension;sars-cov-2;scotland;angiotensin converting enzyme (ace) inhibitor;mortality | Journal Article;Multicenter Study;Observational Study | Khan, Khurram Shahzad;Reed-Embleton, Hamish;Lewis, Jen;Bain, Pamela;Mahmud, Sajid | 10.1177/0036933020951926 | [
1,
0,
0,
1,
0,
0,
0
] | [Title]: Angiotensin converting enzyme inhibitors do not increase the risk of poor outcomes in COVID-19 disease. A multi-centre observational study. [Abstract]: BACKGROUND AND AIMS: Hypertension is associated with an increased risk of severe outcomes with COVID-19 disease. Angiotensin Converting Enzyme (ACE) inhibitors... |
32,245,264 | Pharmaceuticals (Basel) | Emetine, Ipecac, Ipecac Alkaloids and Analogues as Potential Antiviral Agents for Coronaviruses. | The COVID-19 coronavirus is currently spreading around the globe with limited treatment options available. This article presents the rationale for potentially using old drugs (emetine, other ipecac alkaloids or analogues) that have been used to treat amoebiasis in the treatment of COVID-19. Emetine had amongst the lowe... | covid-19;mers;sars;coronavirus;dehydroemetine;emetine;ipecac;repurposing: antiviral;treatment | Journal Article | Bleasel, Martin D;Peterson, Gregory M | 10.3390/ph13030051 | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: Emetine, Ipecac, Ipecac Alkaloids and Analogues as Potential Antiviral Agents for Coronaviruses. [Abstract]: The COVID-19 coronavirus is currently spreading around the globe with limited treatment options available. This article presents the rationale for potentially using old drugs (emetine, other ipecac alka... |
32,434,611 | Ir J Psychol Med | The need for early intervention for psychosis to persist throughout the COVID-19 pandemic and beyond. | In the last three decades, early intervention for psychosis (EIP) services have been established worldwide and have resulted in superior symptomatic and functional outcomes for people affected by psychotic disorders. These improved outcomes are a result of reducing delays to treatment and the provision of specialised, ... | Journal Article | O'Donoghue, B;O'Connor, K;Thompson, A;McGorry, P | 10.1017/ipm.2020.56 | [
0,
0,
1,
0,
0,
0,
0
] | [Title]: The need for early intervention for psychosis to persist throughout the COVID-19 pandemic and beyond. [Abstract]: In the last three decades, early intervention for psychosis (EIP) services have been established worldwide and have resulted in superior symptomatic and functional outcomes for people affected by p... | |
32,400,380 | Ugeskr Laeger | [Lack of clinical evidence for the use of hydroxychloroquine to treat SARS-CoV-2 infection]. | The severity of COVID-19 disease has led to an urgent need for the discovery of new treatments. Thus, global stocks of hydroxychloroquine (HCQ) have been put under pressure with a study of 26 patients treated with HCQ during their infection with SARS-CoV-2. Despite the study's lack of quality, several countries' medici... | Journal Article;Review | Troldborg, Anne;Bartels, Lars Erik;Deleuran, Bent | [
1,
0,
0,
0,
0,
0,
0
] | [Title]: [Lack of clinical evidence for the use of hydroxychloroquine to treat SARS-CoV-2 infection]. [Abstract]: The severity of COVID-19 disease has led to an urgent need for the discovery of new treatments. Thus, global stocks of hydroxychloroquine (HCQ) have been put under pressure with a study of 26 patients treat... |
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