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32,242,347
J Korean Med Sci
Out-of-Hospital Cohort Treatment of Coronavirus Disease 2019 Patients with Mild Symptoms in Korea: an Experience from a Single Community Treatment Center.
The outbreak of Coronavirus Disease 2019 (COVID-19) caused a worldwide pandemic. Less than 6 weeks after the first confirmed cases in Korea, the patient number exceeded 5,000, which overcrowded limited hospital resources and forced confirmed patients to stay at home. To allocate medical resources efficiently, Korea imp...
covid-19;community treatment center;medical resources;sars-cov-2
Journal Article
Park, Peong Gang;Kim, Chang Hyup;Heo, Yoon;Kim, Tae Suk;Park, Chan Woo;Kim, Choong Hyo
10.3346/jkms.2020.35.e140
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Out-of-Hospital Cohort Treatment of Coronavirus Disease 2019 Patients with Mild Symptoms in Korea: an Experience from a Single Community Treatment Center. [Abstract]: The outbreak of Coronavirus Disease 2019 (COVID-19) caused a worldwide pandemic. Less than 6 weeks after the first confirmed cases in Korea, the...
32,661,509
Aging Med (Milton)
Longer incubation period of coronavirus disease 2019 (COVID-19) in older adults.
Objective: The aim of this study was to explore any age-related change in the incubation period of COVID-19, specifically any difference between older (aged >/=65 years) and younger adults. Methods: Based on online data released officially by 21 Chinese cities from January 22 to February 15, 2020, the incubation period...
covid-19;incubation period;older adults
Journal Article
Kong, Tak-Kwan
10.1002/agm2.12114
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Longer incubation period of coronavirus disease 2019 (COVID-19) in older adults. [Abstract]: Objective: The aim of this study was to explore any age-related change in the incubation period of COVID-19, specifically any difference between older (aged >/=65 years) and younger adults. Methods: Based on online dat...
32,244,852
J Clin Med
Smoking Upregulates Angiotensin-Converting Enzyme-2 Receptor: A Potential Adhesion Site for Novel Coronavirus SARS-CoV-2 (Covid-19).
The epicenter of the original outbreak in China has high male smoking rates of around 50%, and early reported death rates have an emphasis on older males, therefore the likelihood of smokers being overrepresented in fatalities is high. In Iran, China, Italy, and South Korea, female smoking rates are much lower than mal...
ace2 receptor;copd;covid-19;electronic cigarettes;heat-not-burn;iqos;sars-cov-2;smoking;vaping
Editorial
Brake, Samuel James;Barnsley, Kathryn;Lu, Wenying;McAlinden, Kielan Darcy;Eapen, Mathew Suji;Sohal, Sukhwinder Singh
10.3390/jcm9030841
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Smoking Upregulates Angiotensin-Converting Enzyme-2 Receptor: A Potential Adhesion Site for Novel Coronavirus SARS-CoV-2 (Covid-19). [Abstract]: The epicenter of the original outbreak in China has high male smoking rates of around 50%, and early reported death rates have an emphasis on older males, therefore t...
32,772,892
J Biomol Struct Dyn
In silico designing of multi-epitope vaccine construct against human coronavirus infections.
Single stranded RNA viruses were known to cause variety of diseases since many years and are gaining much importance due to pandemic after the identification of a novel corona virus (severe acute respiratory syndrome-coronavirus (SARS-CoV-2)). Seven coronaviruses (CoVs) are known to infect humans and they are OC43 CoV,...
coronavirus;epitope;spike protein;toll-like receptor;vaccine
Journal Article
Devi, Arpita;Chaitanya, Nyshadham S N
10.1080/07391102.2020.1804460
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: In silico designing of multi-epitope vaccine construct against human coronavirus infections. [Abstract]: Single stranded RNA viruses were known to cause variety of diseases since many years and are gaining much importance due to pandemic after the identification of a novel corona virus (severe acute respirator...
32,560,746
Trials
Efficacy and safety of aerosolized intra-tracheal dornase alfa administration in patients with SARS-CoV-2-induced acute respiratory distress syndrome (ARDS): a structured summary of a study protocol for a randomised controlled trial.
OBJECTIVES: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) may trigger severe pneumonia in coronavirus disease of 2019 (COVID-19) patients through release of damage-associated molecular patterns (DAMPs) and recruitment of neutrophils in the lungs. Activated neutrophils induce inflammation and severe alveo...
ards;covid-19;dornase alfa;lung damage;neutrophil extracellular traps;randomised controlled trial
Clinical Trial Protocol;Letter;Multicenter Study
Desilles, J P;Gregoire, C;Le Cossec, C;Lambert, J;Mophawe, O;Losser, M R;Lambiotte, F;Le Tacon, S;Cantier, M;Engrand, N;Trouiller, P;Pottecher, J
10.1186/s13063-020-04488-8
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Efficacy and safety of aerosolized intra-tracheal dornase alfa administration in patients with SARS-CoV-2-induced acute respiratory distress syndrome (ARDS): a structured summary of a study protocol for a randomised controlled trial. [Abstract]: OBJECTIVES: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS...
32,977,485
Diseases
Serological Tests for SARS-CoV-2 Coronavirus by Commercially Available Point-of-Care and Laboratory Diagnostics in Pre-COVID-19 Samples in Japan.
The number of COVID-19 patients in Japan is considered low, compared with U.S. and European countries. However, recent serological survey reported that several percent of population showed IgG positive to SARS-CoV-2. Specificity in the assays might influence the estimate, and possibility of overdiagnosis should be inve...
elisa;japan;lfa;sars-cov-2;false positive rate;serological test;specificity
Journal Article
Lyu, Zhaoqing;Harada Sassa, Mariko;Fujitani, Tomoko;Harada, Kouji H
10.3390/diseases8040036
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Serological Tests for SARS-CoV-2 Coronavirus by Commercially Available Point-of-Care and Laboratory Diagnostics in Pre-COVID-19 Samples in Japan. [Abstract]: The number of COVID-19 patients in Japan is considered low, compared with U.S. and European countries. However, recent serological survey reported that s...
33,063,649
Toxicol Ind Health
Return to normal operations: COVID-19 mitigation strategies for workplaces.
As spikes and resurgences of COVID-19 cases continue to increase in different geographical regions across the United States, more and more companies are left with numerous questions about reopening or restarting their operations. The current pandemic in the United States poses unique challenges unlike any other for bus...
covid-19;sars-cov-2;occupational health;pandemic;planning
Journal Article
Parker, Justine;Boles, Corey;Egnot, Natalie;Sundermann, Alexander;Fleeger, Alan
10.1177/0748233720967525
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Return to normal operations: COVID-19 mitigation strategies for workplaces. [Abstract]: As spikes and resurgences of COVID-19 cases continue to increase in different geographical regions across the United States, more and more companies are left with numerous questions about reopening or restarting their opera...
32,808,970
JAMA Intern Med
Evaluating the Association of Clinical Characteristics With Neutralizing Antibody Levels in Patients Who Have Recovered From Mild COVID-19 in Shanghai, China.
Importance: The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) threatens global public health. The association between clinical characteristics of the virus and neutralizing antibodies (NAbs) against this virus have not been well studied. Objective: T...
Journal Article;Research Support, Non-U.S. Gov't
Wu, Fan;Liu, Mei;Wang, Aojie;Lu, Lu;Wang, Qimin;Gu, Chenjian;Chen, Jun;Wu, Yang;Xia, Shuai;Ling, Yun;Zhang, Yuling;Xun, Jingna;Zhang, Rong;Xie, Youhua;Jiang, Shibo;Zhu, Tongyu;Lu, Hongzhou;Wen, Yumei;Huang, Jinghe
10.1001/jamainternmed.2020.4616
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Evaluating the Association of Clinical Characteristics With Neutralizing Antibody Levels in Patients Who Have Recovered From Mild COVID-19 in Shanghai, China. [Abstract]: Importance: The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) threaten...
32,564,140
World J Surg
Impact of Personal Protective Equipment on Surgical Performance During the COVID-19 Pandemic.
BACKGROUND: The Severe Acute Respiratory Syndrome Coronavirus 2 pandemic has exposed surgeons to hazardous working conditions, imposing the need for personal protective equipment (PPE) use during surgery. The use of such equipment may affect their non-technical skills, augment fatigue, and affect performance. This stud...
Journal Article
Yanez Benitez, Carlos;Guemes, Antonio;Aranda, Jose;Ribeiro, Marcelo;Ottolino, Pablo;Di Saverio, Salomone;Alexandrino, Henrique;Ponchietti, Luca;Blas, Juan L;Ramos, Juan Pablo;Rangelova, Elena;Munoz, Mercedes;Yanez, Carlos Sr
10.1007/s00268-020-05648-2
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of Personal Protective Equipment on Surgical Performance During the COVID-19 Pandemic. [Abstract]: BACKGROUND: The Severe Acute Respiratory Syndrome Coronavirus 2 pandemic has exposed surgeons to hazardous working conditions, imposing the need for personal protective equipment (PPE) use during surgery. ...
32,993,405
Immunol Invest
The Mechanical Autophagy as a Part of Cellular Immunity; Facts and Features in Treating the Medical Disorders.
Autophagy is a cellular housekeeping process that incorporates lysosomal-degradation to maintain cell survival and energy sources. In recent decades, the role of autophagy has implicated in the initiation and development of many diseases that affect humanity. Among these diseases are autoimmune diseases and neurodegene...
autophagy;apoptosis;cancer therapy;cellular immune disorder;infectious diseases
Journal Article
Khalil, Hany;Abd ElHady, Amira;Elawdan, Khaled A;Mohamed, Dalia;Mohamed, Doaa D;Abd El Maksoud, Ahmed I;El-Chennawi, Farha A;El-Fikiy, Bhgat;El-Sayed, Ibrahim H
10.1080/08820139.2020.1828453
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The Mechanical Autophagy as a Part of Cellular Immunity; Facts and Features in Treating the Medical Disorders. [Abstract]: Autophagy is a cellular housekeeping process that incorporates lysosomal-degradation to maintain cell survival and energy sources. In recent decades, the role of autophagy has implicated i...
32,478,706
MEDICC Rev
Severe COVID-19 Cases: Is Respiratory Distress Partially Explained by Central Nervous System Involvement?
The main characteristics and challenging symptoms of COVID-19, caused by the novel coronavirus SARS-CoV-2, are related to re-spiratory distress. Although most patients have mild symptoms such as fever, headache, cough, myalgia and anosmia, some develop acute respiratory distress syndrome, leading to death in many cases...
Journal Article
Machado-Curbelo, Calixto
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Severe COVID-19 Cases: Is Respiratory Distress Partially Explained by Central Nervous System Involvement? [Abstract]: The main characteristics and challenging symptoms of COVID-19, caused by the novel coronavirus SARS-CoV-2, are related to re-spiratory distress. Although most patients have mild symptoms such a...
32,787,397
Afr J Prim Health Care Fam Med
Ventilators are not the answer in Africa.
The treatment of severely ill coronavirus disease 2019 (COVID-19) patients has brought the worldwide shortage of oxygen and ventilator-related resources to public attention. Ventilators are considered as the vital equipment needed to manage these patients, who account for 3% - 5% of patients with Covid-19. Most patient...
covid-19;oxygen infrastructure;critical care;district hospital;oxygen concentrator;prone patient;ventilators
Journal Article
Madzimbamuto, Farai D
10.4102/phcfm.v12i1.2517
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Ventilators are not the answer in Africa. [Abstract]: The treatment of severely ill coronavirus disease 2019 (COVID-19) patients has brought the worldwide shortage of oxygen and ventilator-related resources to public attention. Ventilators are considered as the vital equipment needed to manage these patients, ...
32,962,759
Antimicrob Resist Infect Control
A nosocomial cluster of vancomycin resistant enterococci among COVID-19 patients in an intensive care unit.
BACKGROUND: Currently, hospitals have been forced to divert substantial resources to cope with the ongoing coronavirus disease 2019 (COVID-19) pandemic. It is unclear if this situation will affect long-standing infection prevention practices and impact on healthcare associated infections. Here, we report a nosocomial c...
covid-19;healthcare-associated infection;intensive care unit;nosocomial vre cluster;surface contamination;vanb
Journal Article
Kampmeier, Stefanie;Tonnies, Hauke;Correa-Martinez, Carlos L;Mellmann, Alexander;Schwierzeck, Vera
10.1186/s13756-020-00820-8
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A nosocomial cluster of vancomycin resistant enterococci among COVID-19 patients in an intensive care unit. [Abstract]: BACKGROUND: Currently, hospitals have been forced to divert substantial resources to cope with the ongoing coronavirus disease 2019 (COVID-19) pandemic. It is unclear if this situation will a...
33,010,731
Respir Med
Association of sex with clinical outcomes in COVID-19 patients: A retrospective analysis of 1190 cases.
BACKGROUND: The outbreak of COVID-19 caused by SARS-CoV-2 has been a pandemic. The objective of our study was to explore the association between sex and clinical outcomes in patients with COVID-19. METHODS: Detailed clinical data including clinical characteristics, laboratory tests, imaging features and treatments of 1...
covid-19;mortality;organ failure;sex
Journal Article
Liu, Jiao;Zhang, Lidi;Chen, Yizhu;Wu, Zhixiong;Dong, Xuan;Teboul, Jean-Louis;Zhang, Sheng;Ye, Xiaofei;Liu, Yongan;Wang, Tao;Du, Hangxiang;Li, Wenzhe;Chen, Dechang
10.1016/j.rmed.2020.106159
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Association of sex with clinical outcomes in COVID-19 patients: A retrospective analysis of 1190 cases. [Abstract]: BACKGROUND: The outbreak of COVID-19 caused by SARS-CoV-2 has been a pandemic. The objective of our study was to explore the association between sex and clinical outcomes in patients with COVID-1...
32,495,582
Zhongguo Zhong Yao Za Zhi
[Suggestions on design of evidence-based traditional Chinese medicine clinical study for new public health emergencies].
2019 novel coronavirus(2019-nCoV) has occurred for 2 months, and seriously affected the people's health in the world. Therefore, scientific prevention and control strategies and effective intervention measures are the only ways to solve the world problem. In the determination of intervention measures, not only the effe...
2019-ncov;covid-19;clinical trials;evidence-based chinese medicine;methodology;new public health emergencies
Journal Article
Wang, Lian-Xin;Xie, Yan-Ming
10.19540/j.cnki.cjcmm.20200318.501
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: [Suggestions on design of evidence-based traditional Chinese medicine clinical study for new public health emergencies]. [Abstract]: 2019 novel coronavirus(2019-nCoV) has occurred for 2 months, and seriously affected the people's health in the world. Therefore, scientific prevention and control strategies and ...
32,677,081
Int Nurs Rev
The lady with the lamp: Amid the COVID-19 haze.
The COVID-19 pandemic is currently the dominant public health topic across every nation. The world of health care is shrouded in the haze of the COVID-19 pandemic and is experiencing unprecedented patient loads arising from this complicated and unfamiliar viral disease. No one was prepared for this. Unsurprisingly, the...
covid-19;global health;international year of the nurse and midwife;nurses;nursing;pandemics;who
Journal Article
Xiao, Yingqi;Jiang, Xiaolian
10.1111/inr.12599
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The lady with the lamp: Amid the COVID-19 haze. [Abstract]: The COVID-19 pandemic is currently the dominant public health topic across every nation. The world of health care is shrouded in the haze of the COVID-19 pandemic and is experiencing unprecedented patient loads arising from this complicated and unfami...
32,556,553
Ophthalmologe
[First results of investigations of SARS-CoV2 RNA in human corneal tissue].
Preliminary investigations of human corneal tissues from coronavirus disease 2019 (COVID-19) cadaveric donors indicated that no severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA is present. Current eye banking guidelines do not recommend any type of routine testing for SARS-CoV2 RNA in post-mortem donor ...
covid-19;cornea;rt-pcr;tissue donor;tissue procurement and processing
Journal Article;Review
Bayyoud, Tarek;Iftner, Thomas;Bartz-Schmidt, Karl Ulrich;Rohrbach, Jens Martin;Ueffing, Marius;Schindler, Michael;Thaler, Sebastian
10.1007/s00347-020-01151-0
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: [First results of investigations of SARS-CoV2 RNA in human corneal tissue]. [Abstract]: Preliminary investigations of human corneal tissues from coronavirus disease 2019 (COVID-19) cadaveric donors indicated that no severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA is present. Current eye bankin...
32,248,675
Crit Care Resusc
Critically ill patients with COVID-19 in Hong Kong: a multicentre retrospective observational cohort study
Objective: To report the first eight cases of critically ill patients with coronavirus disease 2019 (COVID-19) in Hong Kong, describing the treatments and supportive care they received and their 28-day outcomes. Design: Multicentre retrospective observational cohort study. Setting: Three multidisciplinary intensive car...
Journal Article
Ling, Lowell;So, Christina;Shum, Hoi Ping;Chan, Paul K S;Lai, Christopher K C;Kandamby, Darshana H;Ho, Eunise;So, Dominic;Yan, Wing Wa;Lui, Grace;Leung, Wai Shing;Chan, Man Chun;Gomersall, Charles D
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Critically ill patients with COVID-19 in Hong Kong: a multicentre retrospective observational cohort study [Abstract]: Objective: To report the first eight cases of critically ill patients with coronavirus disease 2019 (COVID-19) in Hong Kong, describing the treatments and supportive care they received and the...
32,633,712
Emerg Infect Dis
Retrospective Description of Pregnant Women Infected with Severe Acute Respiratory Syndrome Coronavirus 2, France.
Fix data are available on the management of pregnant women infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We conducted a retrospective study of 100 pregnant women with SARS-CoV-2 infection in 4 obstetric units in the Paris metropolitan area of France during March 12-April 13, 2020. Among pa...
covid-19;france;mers;sars;sars-cov-2;coronavirus;coronavirus disease;pregnancy;respiratory infections;severe acute respiratory syndrome coronavirus 2;viruses;zoonoses
Journal Article;Multicenter Study
Vivanti, Alexandre J;Mattern, Jeremie;Vauloup-Fellous, Christelle;Jani, Jacques;Rigonnot, Luc;El Hachem, Larissa;Le Gouez, Agnes;Desconclois, Celine;Ben M'Barek, Imane;Sibiude, Jeanne;Benachi, Alexandra;Picone, Olivier;Cordier, Anne-Gael
10.3201/eid2609.202144
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Retrospective Description of Pregnant Women Infected with Severe Acute Respiratory Syndrome Coronavirus 2, France. [Abstract]: Fix data are available on the management of pregnant women infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We conducted a retrospective study of 100 pregnan...
32,881,851
MMWR Morb Mortal Wkly Rep
Timing of State and Territorial COVID-19 Stay-at-Home Orders and Changes in Population Movement - United States, March 1-May 31, 2020.
SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), is thought to spread from person to person primarily by the respiratory route and mainly through close contact (1). Community mitigation strategies can lower the risk for disease transmission by limiting or preventing person-to-person interactions (...
Journal Article
Moreland, Amanda;Herlihy, Christine;Tynan, Michael A;Sunshine, Gregory;McCord, Russell F;Hilton, Charity;Poovey, Jason;Werner, Angela K;Jones, Christopher D;Fulmer, Erika B;Gundlapalli, Adi V;Strosnider, Heather;Potvien, Aaron;Garcia, Macarena C;Honeycutt, Sally;Baldwin, Grant
10.15585/mmwr.mm6935a2
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Timing of State and Territorial COVID-19 Stay-at-Home Orders and Changes in Population Movement - United States, March 1-May 31, 2020. [Abstract]: SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), is thought to spread from person to person primarily by the respiratory route and mainly thro...
32,570,240
Oncology
Clinical Characteristics of Metastatic Prostate Cancer Patients Infected with COVID-19 in South Italy.
BACKGROUND: To date, the clinical characteristics of coronavirus disease 19 (COVID-19)-infected urologic cancer patients are unknown. METHODS: We have analyzed all patients with prostate cancer undergoing hormonal or chemotherapy treatment and receiving telephone and in person pre-triage between March 1 and 27, 2020, a...
comorbidities;coronavirus disease sars-cov-2;drug interaction;hormonal therapy;prostate cancer
News
Di Lorenzo, Giuseppe;Buonerba, Luciana;Ingenito, Concetta;Crocetto, Felice;Buonerba, Carlo;Libroia, Annamaria;Sciarra, Antonella;Ragone, Gianluca;Sanseverino, Roberto;Iaccarino, Simona;Napodano, Giorgio;Imbimbo, Ciro;Leo, Emilio;Kozlakidis, Zisis;De Placido, Sabino
10.1159/000509434
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Clinical Characteristics of Metastatic Prostate Cancer Patients Infected with COVID-19 in South Italy. [Abstract]: BACKGROUND: To date, the clinical characteristics of coronavirus disease 19 (COVID-19)-infected urologic cancer patients are unknown. METHODS: We have analyzed all patients with prostate cancer un...
32,155,105
Radiology
Performance of Radiologists in Differentiating COVID-19 from Non-COVID-19 Viral Pneumonia at Chest CT.
Background Despite its high sensitivity in diagnosing coronavirus disease 2019 (COVID-19) in a screening population, the chest CT appearance of COVID-19 pneumonia is thought to be nonspecific. Purpose To assess the performance of radiologists in the United States and China in differentiating COVID-19 from viral pneumon...
Journal Article;Multicenter Study;Research Support, Non-U.S. Gov't
Bai, Harrison X;Hsieh, Ben;Xiong, Zeng;Halsey, Kasey;Choi, Ji Whae;Tran, Thi My Linh;Pan, Ian;Shi, Lin-Bo;Wang, Dong-Cui;Mei, Ji;Jiang, Xiao-Long;Zeng, Qiu-Hua;Egglin, Thomas K;Hu, Ping-Feng;Agarwal, Saurabh;Xie, Fang-Fang;Li, Sha;Healey, Terrance;Atalay, Michael K;Liao, Wei-Hua
10.1148/radiol.2020200823
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Performance of Radiologists in Differentiating COVID-19 from Non-COVID-19 Viral Pneumonia at Chest CT. [Abstract]: Background Despite its high sensitivity in diagnosing coronavirus disease 2019 (COVID-19) in a screening population, the chest CT appearance of COVID-19 pneumonia is thought to be nonspecific. Pur...
33,037,070
CMAJ Open
Heterogeneity in testing, diagnosis and outcome in SARS-CoV-2 infection across outbreak settings in the Greater Toronto Area, Canada: an observational study.
BACKGROUND: Congregate settings have been disproportionately affected by coronavirus disease 2019 (COVID-19). Our objective was to compare testing for, diagnosis of and death after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection across 3 settings (residents of long-term care homes, people living ...
Comparative Study;Journal Article;Observational Study;Research Support, Non-U.S. Gov't
Wang, Linwei;Ma, Huiting;Yiu, Kristy C Y;Calzavara, Andrew;Landsman, David;Luong, Linh;Chan, Adrienne K;Kustra, Rafal;Kwong, Jeffrey C;Boily, Marie-Claude;Hwang, Stephen;Straus, Sharon;Baral, Stefan D;Mishra, Sharmistha
10.9778/cmajo.20200213
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Heterogeneity in testing, diagnosis and outcome in SARS-CoV-2 infection across outbreak settings in the Greater Toronto Area, Canada: an observational study. [Abstract]: BACKGROUND: Congregate settings have been disproportionately affected by coronavirus disease 2019 (COVID-19). Our objective was to compare te...
33,033,172
Sci Immunol
Persistence and decay of human antibody responses to the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 patients.
We measured plasma and/or serum antibody responses to the receptor-binding domain (RBD) of the spike (S) protein of SARS-CoV-2 in 343 North American patients infected with SARS-CoV-2 (of which 93% required hospitalization) up to 122 days after symptom onset and compared them to responses in 1548 individuals whose blood...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Iyer, Anita S;Jones, Forrest K;Nodoushani, Ariana;Kelly, Meagan;Becker, Margaret;Slater, Damien;Mills, Rachel;Teng, Erica;Kamruzzaman, Mohammad;Garcia-Beltran, Wilfredo F;Astudillo, Michael;Yang, Diane;Miller, Tyler E;Oliver, Elizabeth;Fischinger, Stephanie;Atyeo, Caroline;Iafrate, A John;Calderwood, Stephen B;Lauer, S...
10.1126/sciimmunol.abe0367
[ 0, 1, 0, 1, 0, 0, 0 ]
[Title]: Persistence and decay of human antibody responses to the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 patients. [Abstract]: We measured plasma and/or serum antibody responses to the receptor-binding domain (RBD) of the spike (S) protein of SARS-CoV-2 in 343 North American patients infected w...
32,638,938
Sao Paulo Med J
Evaluation of knowledge and attitudes among intensive care physicians during the COVID-19 pandemic: a cross-sectional survey.
BACKGROUND: The novel coronavirus (COVID-19) emerged in Wuhan, China, in December 2019. OBJECTIVES: To evaluate the knowledge of intensive care physicians in Turkey about COVID-19 and their attitudes towards the strategies and application methods to be used for COVID-19 cases that need to be followed up in an intensive...
Journal Article
Erbas, Mesut;Dost, Burhan
10.1590/1516-3180.2020.02545062020
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Evaluation of knowledge and attitudes among intensive care physicians during the COVID-19 pandemic: a cross-sectional survey. [Abstract]: BACKGROUND: The novel coronavirus (COVID-19) emerged in Wuhan, China, in December 2019. OBJECTIVES: To evaluate the knowledge of intensive care physicians in Turkey about CO...
32,406,536
J Bone Miner Res
Osteoporosis Management in the Era of COVID-19.
Osteoporosis is a chronic condition that reflects reduced bone strength and an associated increased risk for fracture. As a chronic condition, osteoporosis generally requires sustained medical intervention(s) to limit the risks for additional bone loss, compromise of skeletal integrity, and fracture occurrence. Further...
abaloparatide;bisphosphonat;covid-19;denosumab;fractures;osteoporosis;romosozumab;teriparatide
Congress;Practice Guideline
Yu, Elaine W;Tsourdi, Elena;Clarke, Bart L;Bauer, Douglas C;Drake, Matthew T
10.1002/jbmr.4049
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Osteoporosis Management in the Era of COVID-19. [Abstract]: Osteoporosis is a chronic condition that reflects reduced bone strength and an associated increased risk for fracture. As a chronic condition, osteoporosis generally requires sustained medical intervention(s) to limit the risks for additional bone los...
32,813,760
Einstein (Sao Paulo)
Epidemiologic and clinical features of patients with COVID-19 in Brazil.
Objective This study describes epidemiological and clinical features of patients with confirmed infection by SARS-CoV-2 diagnosed and treated at Hospital Israelita Albert Einstein , which admitted the first patients with this condition in Brazil. Methods In this retrospective, single-center study, we included all labor...
Journal Article
Teich, Vanessa Damazio;Klajner, Sidney;Almeida, Felipe Augusto Santiago de;Dantas, Anna Carolina Batista;Laselva, Claudia Regina;Torritesi, Mariana Galvani;Canero, Tatiane Ramos;Berwanger, Otavio;Rizzo, Luiz Vicente;Reis, Eduardo Pontes;Cendoroglo Neto, Miguel
10.31744/einstein_journal/2020ao6022
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Epidemiologic and clinical features of patients with COVID-19 in Brazil. [Abstract]: Objective This study describes epidemiological and clinical features of patients with confirmed infection by SARS-CoV-2 diagnosed and treated at Hospital Israelita Albert Einstein , which admitted the first patients with this ...
32,519,842
ACS Nano
Toward Nanotechnology-Enabled Approaches against the COVID-19 Pandemic.
The COVID-19 outbreak has fueled a global demand for effective diagnosis and treatment as well as mitigation of the spread of infection, all through large-scale approaches such as specific alternative antiviral methods and classical disinfection protocols. Based on an abundance of engineered materials identifiable by t...
Journal Article;Research Support, Non-U.S. Gov't;Review
Weiss, Carsten;Carriere, Marie;Fusco, Laura;Capua, Ilaria;Regla-Nava, Jose Angel;Pasquali, Matteo;Scott, James A;Vitale, Flavia;Unal, Mehmet Altay;Mattevi, Cecilia;Bedognetti, Davide;Merkoci, Arben;Tasciotti, Ennio;Yilmazer, Acelya;Gogotsi, Yury;Stellacci, Francesco;Delogu, Lucia Gemma
10.1021/acsnano.0c03697
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Toward Nanotechnology-Enabled Approaches against the COVID-19 Pandemic. [Abstract]: The COVID-19 outbreak has fueled a global demand for effective diagnosis and treatment as well as mitigation of the spread of infection, all through large-scale approaches such as specific alternative antiviral methods and clas...
32,936,947
Cochrane Database Syst Rev
Antimicrobial mouthwashes (gargling) and nasal sprays to protect healthcare workers when undertaking aerosol-generating procedures (AGPs) on patients without suspected or confirmed COVID-19 infection.
BACKGROUND: COVID-19 infection poses a serious risk to patients and - due to its contagious nature - to those healthcare workers (HCWs) treating them. The risks of transmission of infection are greater when a patient is undergoing an aerosol-generating procedure (AGP). Not all those with COVID-19 infection are symptoma...
Journal Article;Research Support, Non-U.S. Gov't;Systematic Review
Burton, Martin J;Clarkson, Janet E;Goulao, Beatriz;Glenny, Anne-Marie;McBain, Andrew J;Schilder, Anne Gm;Webster, Katie E;Worthington, Helen V
10.1002/14651858.CD013628.pub2
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Antimicrobial mouthwashes (gargling) and nasal sprays to protect healthcare workers when undertaking aerosol-generating procedures (AGPs) on patients without suspected or confirmed COVID-19 infection. [Abstract]: BACKGROUND: COVID-19 infection poses a serious risk to patients and - due to its contagious nature...
33,062,736
J Educ Health Promot
Coronavirus disease 2019 (COVID-19) surveillance system: Development of COVID-19 minimum data set and interoperable reporting framework.
INTRODUCTION: The 2019 coronavirus disease (COVID-19) is a major global health concern. Joint efforts for effective surveillance of COVID-19 require immediate transmission of reliable data. In this regard, a standardized and interoperable reporting framework is essential in a consistent and timely manner. Thus, this re...
covid-19;coronavirus disease 2019;minimum data set;semantic interoperability;surveillance system
Journal Article
Shanbehzadeh, Mostafa;Kazemi-Arpanahi, Hadi;Mazhab-Jafari, Komeil;Haghiri, Hamideh
10.4103/jehp.jehp_456_20
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Coronavirus disease 2019 (COVID-19) surveillance system: Development of COVID-19 minimum data set and interoperable reporting framework. [Abstract]: INTRODUCTION: The 2019 coronavirus disease (COVID-19) is a major global health concern. Joint efforts for effective surveillance of COVID-19 require immediate tra...
33,075,138
Clin Infect Dis
Self-Collected Oral Fluid and Nasal Swab Specimens Demonstrate Comparable Sensitivity to Clinician-Collected Nasopharyngeal Swab Specimens for the Detection of SARS-CoV-2.
We compared self-collected oral fluid swab specimens with and without clinician supervision, clinician-supervised self-collected mid-turbinate (nasal) swab specimens, and clinician-collected nasopharyngeal swab specimens for the detection of SARS-CoV-2. Supervised oral fluid and nasal swab specimens performed similarly...
Journal Article
Kojima, N;Turner, F;Slepnev, V;Bacelar, A;Deming, L;Kodeboyina, S;Klausner, J D
10.1093/cid/ciaa1589
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Self-Collected Oral Fluid and Nasal Swab Specimens Demonstrate Comparable Sensitivity to Clinician-Collected Nasopharyngeal Swab Specimens for the Detection of SARS-CoV-2. [Abstract]: We compared self-collected oral fluid swab specimens with and without clinician supervision, clinician-supervised self-collecte...
32,621,294
Br J Soc Psychol
Mapping public health responses with attitude networks: the emergence of opinion-based groups in the UK's early COVID-19 response phase.
Partisan patterns of compliance with public health measures are a feature of early COVID-19 responses. In many cases, these differences in behaviour relate to pre-existing group identities. However, in times of rapid societal change, novel opinion-based groups can emerge and provide a new basis for partisan identificat...
covid-19;attitude networks;identity;opinion-based groups;political polarization
Journal Article
Maher, Paul J;MacCarron, Padraig;Quayle, Michael
10.1111/bjso.12396
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Mapping public health responses with attitude networks: the emergence of opinion-based groups in the UK's early COVID-19 response phase. [Abstract]: Partisan patterns of compliance with public health measures are a feature of early COVID-19 responses. In many cases, these differences in behaviour relate to pre...
32,730,733
Emerg Infect Dis
Differential Tropism of SARS-CoV and SARS-CoV-2 in Bat Cells.
Severe acute respiratory syndrome coronavirus 2 did not replicate efficiently in 13 bat cell lines, whereas severe acute respiratory syndrome coronavirus replicated efficiently in kidney cells of its ancestral host, the Rhinolophus sinicus bat, suggesting different evolutionary origins. Structural modeling showed that ...
covid-19;sars;sars-cov-2;sars-related coronavirus;bat;coronavirus disease;origin;respiratory infections;severe acute respiratory syndrome;severe acute respiratory syndrome coronavirus 2;tropism;viruses;zoonoses
Journal Article;Research Support, Non-U.S. Gov't
Lau, Susanna K P;Wong, Antonio C P;Luk, Hayes K H;Li, Kenneth S M;Fung, Joshua;He, Zirong;Cheng, Flora K K;Chan, Tony T Y;Chu, Stella;Aw-Yong, Kam Leng;Lau, Terrence C K;Fung, Kitty S C;Woo, Patrick C Y
10.3201/eid2612.202308
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Differential Tropism of SARS-CoV and SARS-CoV-2 in Bat Cells. [Abstract]: Severe acute respiratory syndrome coronavirus 2 did not replicate efficiently in 13 bat cell lines, whereas severe acute respiratory syndrome coronavirus replicated efficiently in kidney cells of its ancestral host, the Rhinolophus sinic...
33,042,287
Optim Lett
Personnel scheduling during Covid-19 pandemic.
This paper addresses a real-life personnel scheduling problem in the context of Covid-19 pandemic, arising in a large Italian pharmaceutical distribution warehouse. In this case study, the challenge is to determine a schedule that attempts to meet the contractual working time of the employees, considering the fact that...
covid-19;integer programming;personnel scheduling;risk
Journal Article
Zucchi, Giorgio;Iori, Manuel;Subramanian, Anand
10.1007/s11590-020-01648-2
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Personnel scheduling during Covid-19 pandemic. [Abstract]: This paper addresses a real-life personnel scheduling problem in the context of Covid-19 pandemic, arising in a large Italian pharmaceutical distribution warehouse. In this case study, the challenge is to determine a schedule that attempts to meet the ...
33,054,297
Rev Esp Enferm Dig
SARS-CoV-2 and acute pancreatitis: a new etiological agent?
We hereby report a case of COVID-19 who presented acute pancreatitis (AP) without any other risk factors, which emphasizes the possibility of considering SARS-CoV-2 as a new etiological agent for AP. We suggest the study of pancreatic enzymes in COVID-19 patients with gastrointestinal symptoms, which may reveal pancrea...
Case Reports;Letter
Fernandes, Daniel Alvarenga;Yumioka, Aline Satomi;Filho, Helio Ranes de Menezes
10.17235/reed.2020.7481/2020
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: SARS-CoV-2 and acute pancreatitis: a new etiological agent? [Abstract]: We hereby report a case of COVID-19 who presented acute pancreatitis (AP) without any other risk factors, which emphasizes the possibility of considering SARS-CoV-2 as a new etiological agent for AP. We suggest the study of pancreatic enzy...
32,841,429
J Med Virol
Saliva sample pooling for the detection of SARS-CoV-2.
As the battle against coronavirus disease 2019 pandemic continues, an increase in workload and medical expenses have been a concern to the health care system worldwide. Developing a measure that helps to conserve the health care resource is, therefore, highly desirable, and the pooling of the specimens for testing is o...
covid-19;rt-pcr;sars-cov-2;pooling;saliva
Journal Article;Research Support, Non-U.S. Gov't
Pasomsub, Ekawat;Watcharananan, Siriorn P;Watthanachockchai, Treewat;Rakmanee, Kingkan;Tassaneetrithep, Boonrat;Kiertiburanakul, Sasisopin;Phuphuakrat, Angsana
10.1002/jmv.26460
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Saliva sample pooling for the detection of SARS-CoV-2. [Abstract]: As the battle against coronavirus disease 2019 pandemic continues, an increase in workload and medical expenses have been a concern to the health care system worldwide. Developing a measure that helps to conserve the health care resource is, th...
32,679,775
Biomolecules
Deamidated Human Triosephosphate Isomerase is a Promising Druggable Target.
Therapeutic strategies for the treatment of any severe disease are based on the discovery and validation of druggable targets. The human genome encodes only 600-1500 targets for small-molecule drugs, but posttranslational modifications lead to a considerably larger druggable proteome. The spontaneous conversion of aspa...
ages;glycolysis;sars-cov-2;docking;omeprazole;protein structure;triosephosphate isomerase
Journal Article;Research Support, Non-U.S. Gov't
Enriquez-Flores, Sergio;Flores-Lopez, Luis Antonio;Garcia-Torres, Itzhel;de la Mora-de la Mora, Ignacio;Cabrera, Nallely;Gutierrez-Castrellon, Pedro;Martinez-Perez, Yoalli;Lopez-Velazquez, Gabriel
10.3390/biom10071050
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Deamidated Human Triosephosphate Isomerase is a Promising Druggable Target. [Abstract]: Therapeutic strategies for the treatment of any severe disease are based on the discovery and validation of druggable targets. The human genome encodes only 600-1500 targets for small-molecule drugs, but posttranslational m...
32,571,224
BMC Infect Dis
COVID-19 with acute cholecystitis: a case report.
BACKGROUND: The 2019 novel coronavirus (COVID-19) presents a major threat to public health and has rapidly spread worldwide since the outbreak in Wuhan, Hubei Province, China in 2019. To date, there have been few reports of the varying degrees of illness caused by the COVID-19. CASE PRESENTATION: A case of 68-year-old ...
2019-ncov;acute cholecystitis;covid-19;computed tomography;pneumonia
Case Reports;Journal Article
Ying, Mingliang;Lu, Bin;Pan, Jiangfeng;Lu, Guanghong;Zhou, Shaobin;Wang, Dingjun;Li, Lu;Shen, Junkang;Shu, Jiner
10.1186/s12879-020-05164-7
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: COVID-19 with acute cholecystitis: a case report. [Abstract]: BACKGROUND: The 2019 novel coronavirus (COVID-19) presents a major threat to public health and has rapidly spread worldwide since the outbreak in Wuhan, Hubei Province, China in 2019. To date, there have been few reports of the varying degrees of il...
32,582,323
Pak J Med Sci
Risk Assessment of Healthcare Workers at the Frontline against COVID-19.
The novel coronavirus disease 2019 (COVID-19) is a global pandemic. Healthcare workers (HCWs) are on the frontline of treating patients infected with COVID-19. However, data related to its infection rate among HCWs are limited. The aim was to present evidence associated with the number of HCWs being infected with COVID...
covid-19;healthcare;mortality rate;personal protective equipment;risk
Journal Article
Ali, Saqib;Noreen, Sara;Farooq, Imran;Bugshan, Amr;Vohra, Fahim
10.12669/pjms.36.COVID19-S4.2790
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Risk Assessment of Healthcare Workers at the Frontline against COVID-19. [Abstract]: The novel coronavirus disease 2019 (COVID-19) is a global pandemic. Healthcare workers (HCWs) are on the frontline of treating patients infected with COVID-19. However, data related to its infection rate among HCWs are limited...
32,815,354
Tidsskr Nor Laegeforen
Komplikasjoner og dodelighet blant pasienter innlagt med covid-19.
BACKGROUND: The course of disease, complications and hospital mortality among patients with COVID-19 admitted to Norwegian hospitals has not been widely described. The purpose of this study was to survey patients with COVID-19 admitted to a local hospital. MATERIAL AND METHOD: The data were retrieved from a prospective...
Journal Article;Observational Study
Ihle-Hansen, Hakon;Berge, Trygve;Erno, Per Erik;Ronning, Else Johanne;Svendsen, Jan;Wien, Tale Norbye;Tveita, Anders;Andersen, Elizabeth Lyster;Thallinger, Monica;Tveit, Arnljot;Myrstad, Marius
10.4045/tidsskr.20.0432
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Komplikasjoner og dodelighet blant pasienter innlagt med covid-19. [Abstract]: BACKGROUND: The course of disease, complications and hospital mortality among patients with COVID-19 admitted to Norwegian hospitals has not been widely described. The purpose of this study was to survey patients with COVID-19 admit...
33,062,954
ACS Pharmacol Transl Sci
Can Papain-like Protease Inhibitors Halt SARS-CoV-2 Replication?
SARS-CoV-2 encoded papain-like protease (PLpro) harbors a labile Zn site (Cys189-X-X-Cys192-X n -Cys224-X-Cys226) and a classic catalytic site (Cys111-His272-Asp286), which play key roles for viral replication and hence represent promising drug targets. In this Viewpoint, both sulfur-based drugs and peptides-based inhi...
Journal Article
Maiti, Biplab K
10.1021/acsptsci.0c00093
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Can Papain-like Protease Inhibitors Halt SARS-CoV-2 Replication? [Abstract]: SARS-CoV-2 encoded papain-like protease (PLpro) harbors a labile Zn site (Cys189-X-X-Cys192-X n -Cys224-X-Cys226) and a classic catalytic site (Cys111-His272-Asp286), which play key roles for viral replication and hence represent prom...
32,871,848
In Vivo
Clinical Study of Hyperglycemia and SARS-CoV-2 Infection in Intensive Care Unit Patients.
BACKGROUND/AIM: Reports indicate that coronaviridae may inhibit insulin secretion. In this report we aimed to describe the course of glycemia in critically ill patients with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. PATIENTS AND METHODS: We studied 36 SARS-CoV-2 patients (with no history o...
coronaviridae;human;hyperglycemia;intensive care units;severe acute respiratory syndrome
Journal Article
Ilias, Ioannis;Jahaj, Edison;Kokkoris, Stylianos;Zervakis, Dimitrios;Temperikidis, Prodromos;Magira, Eleni;Pratikaki, Maria;Vassiliou, Alice G;Routsi, Christina;Kotanidou, Anastasia;Dimopoulou, Ioanna
10.21873/invivo.12136
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical Study of Hyperglycemia and SARS-CoV-2 Infection in Intensive Care Unit Patients. [Abstract]: BACKGROUND/AIM: Reports indicate that coronaviridae may inhibit insulin secretion. In this report we aimed to describe the course of glycemia in critically ill patients with severe acute respiratory syndrome c...
32,928,816
BMJ Case Rep
Child with tuberculous meningitis and COVID-19 coinfection complicated by extensive cerebral sinus venous thrombosis.
We herein report a case of a child with tuberculous meningitis and COVID-19 coinfection complicated by hydrocephalus, arterial ischaemic stroke and extensive cerebral sinus venous thrombosis. Both conditions induce a proinflammatory cytokine drive resulting, among others, in a prothrombotic state. The disruption of the...
global health;infections;neurology (drugs and medicines);paediatrics (drugs and medicines);radiology (diagnostics)
Case Reports;Journal Article
Essajee, Farida;Solomons, Regan;Goussard, Pierre;Van Toorn, Ronald
10.1136/bcr-2020-238597
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Child with tuberculous meningitis and COVID-19 coinfection complicated by extensive cerebral sinus venous thrombosis. [Abstract]: We herein report a case of a child with tuberculous meningitis and COVID-19 coinfection complicated by hydrocephalus, arterial ischaemic stroke and extensive cerebral sinus venous t...
32,485,418
Thromb Res
Thrombosis risk associated with COVID-19 infection. A scoping review.
BACKGROUND: Infection by the 2019 novel coronavirus (COVID-19) has been reportedly associated with a high risk of thrombotic complications. So far information is scarce and rapidly emerging. METHODS: We conducted a scoping review using a single engine search for studies assessing thrombosis and coagulopathy in COVID-19...
anticoagulation;covid-19;venous thromboembolism
Journal Article;Meta-Analysis;Review
Al-Ani, Fatimah;Chehade, Samer;Lazo-Langner, Alejandro
10.1016/j.thromres.2020.05.039
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Thrombosis risk associated with COVID-19 infection. A scoping review. [Abstract]: BACKGROUND: Infection by the 2019 novel coronavirus (COVID-19) has been reportedly associated with a high risk of thrombotic complications. So far information is scarce and rapidly emerging. METHODS: We conducted a scoping review...
33,059,040
Clin Gastroenterol Hepatol
Benign Evolution of SARS-Cov2 Infections in Children With Inflammatory Bowel Disease: Results From Two International Databases.
The coronavirus disease 2019 (COVID-19) pandemic caused by the highly infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents most often with mild clinical symptoms, but the severe forms are of major concern.(1) SARS-CoV-2 enters human cells via the angiotensin-converting enzyme 2 receptor, exp...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Brenner, Erica J;Pigneur, Benedicte;Focht, Gili;Zhang, Xian;Ungaro, Ryan C;Colombel, Jean-Frederic;Turner, Dan;Kappelman, Michael D;Ruemmele, Frank M
10.1016/j.cgh.2020.10.010
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Benign Evolution of SARS-Cov2 Infections in Children With Inflammatory Bowel Disease: Results From Two International Databases. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic caused by the highly infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents most often with mild...
32,747,165
J Am Pharm Assoc (2003)
The concern about ACE/ARB and COVID-19: Time to hold your horses!
Concern about coronavirus 2019 (COVID-19) morbidity and mortality has drawn attention to the potential role of angiotensin-converting enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) because the SARS-CoV-2 uses the ACE2 receptor as its point of entry into the body. It is not clear if and to what degree ...
Journal Article
Pergolizzi, Joseph V Jr;Varrassi, Giustino;Magnusson, Peter;LeQuang, Jo Ann;Leopoulou, Marianna;Paladini, Antonella;Taylor, Robert;Wollmuth, Charles;Breve, Frank
10.1016/j.japh.2020.06.026
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The concern about ACE/ARB and COVID-19: Time to hold your horses! [Abstract]: Concern about coronavirus 2019 (COVID-19) morbidity and mortality has drawn attention to the potential role of angiotensin-converting enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) because the SARS-CoV-2 uses the AC...
32,662,742
Mult Scler
COVID-19 in multiple sclerosis: The Dutch experience.
Here, we provide an extensive overview of all reported COVID-19 cases in multiple sclerosis (MS) patients in the Netherlands between 27 February and 9 June 2020, gathered by the Dutch MS Taskforce of the Netherlands Society of Neurology. A total of 86 MS patients were reported, 43 of whom tested positive for COVID-19. ...
covid-19;multiple sclerosis;disease-modifying treatment;lymphocytes
Journal Article
Loonstra, Floor C;Hoitsma, Elske;van Kempen, Zoe LE;Killestein, Joep;Mostert, Jop P
10.1177/1352458520942198
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 in multiple sclerosis: The Dutch experience. [Abstract]: Here, we provide an extensive overview of all reported COVID-19 cases in multiple sclerosis (MS) patients in the Netherlands between 27 February and 9 June 2020, gathered by the Dutch MS Taskforce of the Netherlands Society of Neurology. A total...
32,503,662
Trials
Norwegian Coronavirus Disease 2019 (NO COVID-19) Pragmatic Open label Study to assess early use of hydroxychloroquine sulphate in moderately severe hospitalised patients with coronavirus disease 2019: A structured summary of a study protocol for a randomised controlled trial.
OBJECTIVES: The hypothesis of the study is that treatment with hydroxychloroquine sulphate in hospitalised patients with coronavirus disease 2019 (Covid-19) is safe and will accelerate the virological clearance rate for patients with moderately severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) when compared ...
covid-19;chloroquine;oropharyngeal sampling;polymerase chain reaction;pragmatic trial;protocol;randomized controlled trial;viral load
Clinical Trial Protocol;Letter
Lyngbakken, Magnus Nakrem;Berdal, Jan-Erik;Eskesen, Arne;Kvale, Dag;Olsen, Inge Christoffer;Rangberg, Anbjorg;Jonassen, Christine Monceyron;Omland, Torbjorn;Rosjo, Helge;Dalgard, Olav
10.1186/s13063-020-04420-0
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Norwegian Coronavirus Disease 2019 (NO COVID-19) Pragmatic Open label Study to assess early use of hydroxychloroquine sulphate in moderately severe hospitalised patients with coronavirus disease 2019: A structured summary of a study protocol for a randomised controlled trial. [Abstract]: OBJECTIVES: The hypoth...
32,558,961
J Med Virol
The impact of the SARS-CoV-2 infection, with special reference to the hematological setting.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a disease known from a few months, caused by a recently arisen virus and, consequently, it is little known. The disease has a benign course in most infected subjects (children and young adults), is often symptomatic in adults over the age of 50 and often s...
covid-19;sars-cov-2;hematological diseases
Journal Article;Review
Sica, Antonello;Casale, Danilo;Rossi, Giovanni;Casale, Beniamino;Ciccozzi, Massimo;Fasano, Morena;Ciotti, Marco;Sagnelli, Evangelista;Papa, Alfonso;Sagnelli, Caterina
10.1002/jmv.26197
[ 1, 1, 1, 0, 0, 0, 0 ]
[Title]: The impact of the SARS-CoV-2 infection, with special reference to the hematological setting. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a disease known from a few months, caused by a recently arisen virus and, consequently, it is little known. The disease has a benign course in...
32,990,108
J Interprof Care
Bolstering clinician resilience through an interprofessional, web-based nightly debriefing program for emergency departments during the COVID-19 pandemic.
The COVID-19 pandemic has instigated significant changes for health care systems. With clinician burnout rising, efforts to promote clinician resilience are essential. Within this quality improvement project, an interprofessional debriefing program (Brigham Resilience in COVID-19-pandemic Emergency Forum-BRIEF) was dev...
debriefing;clinician burnout;process improvement;resilience
Journal Article
Azizoddin, Desiree R;Vella Gray, Kristen;Dundin, Andrew;Szyld, Demian
10.1080/13561820.2020.1813697
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Bolstering clinician resilience through an interprofessional, web-based nightly debriefing program for emergency departments during the COVID-19 pandemic. [Abstract]: The COVID-19 pandemic has instigated significant changes for health care systems. With clinician burnout rising, efforts to promote clinician re...
32,837,587
Cell Mol Bioeng
Scalable COVID-19 Detection Enabled by Lab-on-Chip Biosensors.
Introduction: The emergence of a novel coronavirus, SARS-CoV-2, has highlighted the need for rapid, accurate, and point-of-care diagnostic testing. As of now, there is not enough testing capacity in the world to meet the stated testing targets, which are expected to skyrocket globally for broader testing during reopeni...
biosensor;covid-19;coronavirus;diagnostic;lab-on-chip
Journal Article
Tymm, Carly;Zhou, Junhu;Tadimety, Amogha;Burklund, Alison;Zhang, John X J
10.1007/s12195-020-00642-z
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Scalable COVID-19 Detection Enabled by Lab-on-Chip Biosensors. [Abstract]: Introduction: The emergence of a novel coronavirus, SARS-CoV-2, has highlighted the need for rapid, accurate, and point-of-care diagnostic testing. As of now, there is not enough testing capacity in the world to meet the stated testing ...
32,422,288
Ann Vasc Surg
Endovascular Treatment of a Ruptured Pararenal Abdominal Aortic Aneurysm in a Patient With Coronavirus Disease-2019: Suggestions and Case Report.
The aim of this report is to discuss emergent repair for complex aortic diseases in patients affected by novel coronavirus pneumonia (coronavirus disease-2019 [COVID-19]), describing a case of ruptured pararenal aortic aneurysm. An eighty-year-old man with COVID-19 was admitted for ruptured aneurysm of the pararenal ao...
Case Reports;Journal Article
Rinaldi, Luigi Federico;Marazzi, Giulia;Marone, Enrico Maria
10.1016/j.avsg.2020.05.011
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Endovascular Treatment of a Ruptured Pararenal Abdominal Aortic Aneurysm in a Patient With Coronavirus Disease-2019: Suggestions and Case Report. [Abstract]: The aim of this report is to discuss emergent repair for complex aortic diseases in patients affected by novel coronavirus pneumonia (coronavirus disease...
32,705,906
Expert Rev Gastroenterol Hepatol
MAFLD in COVID-19 patients: an insidious enemy.
The pandemic Sars-CoV-2 infection represents a dramatic health challenge worldwide. Pneumonia is considered the major damage caused by the virus. However, recent data have highlighted the impact of the Sars-CoV-2 related disease namely COVID-19 on the liver. Hepatic abnormalities significantly increase during COVID-19 ...
covid-19;mafld;sars-cov-2;infection;progressive liver disease
Editorial
Dongiovanni, Paola;Meroni, Marica;Longo, Miriam;Fracanzani, Anna Ludovica
10.1080/17474124.2020.1801417
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: MAFLD in COVID-19 patients: an insidious enemy. [Abstract]: The pandemic Sars-CoV-2 infection represents a dramatic health challenge worldwide. Pneumonia is considered the major damage caused by the virus. However, recent data have highlighted the impact of the Sars-CoV-2 related disease namely COVID-19 on the...
32,834,997
J Pediatr Surg Case Rep
Intussusception in an infant as a manifestation of COVID-19.
Gastrointestinal manifestations of COVID-19 are rare and have primarily been limited to diarrhea or vomiting. Intussusception is the most common cause of bowel obstruction in infants, with up to 30% of pediatric intussusception cases having a preceding viral illness. We present the rare case of intussusception in a SAR...
covid-19;intussusception;pediatric
Case Reports
Moazzam, Zorays;Salim, Areej;Ashraf, Alina;Jehan, Fyezah;Arshad, Muhammad
10.1016/j.epsc.2020.101533
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Intussusception in an infant as a manifestation of COVID-19. [Abstract]: Gastrointestinal manifestations of COVID-19 are rare and have primarily been limited to diarrhea or vomiting. Intussusception is the most common cause of bowel obstruction in infants, with up to 30% of pediatric intussusception cases havi...
32,844,707
J Int Med Res
Easy-to-use electrocautery smoke evacuation device for open surgery under the risk of the COVID-19 pandemic.
OBJECTIVE: This study was performed to introduce an easy method of surgical smoke evacuation for patients with confirmed or suspected COVID-19 undergoing emergency surgery. METHODS: An easy, inexpensive, protective, and practical surgical smoke evacuation device/system was developed and is herein described. RESULTS: Th...
covid-19;open surgery;electrocautery;smoke evacuation;transmission;virus
Journal Article
Ekci, Baki
10.1177/0300060520949772
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Easy-to-use electrocautery smoke evacuation device for open surgery under the risk of the COVID-19 pandemic. [Abstract]: OBJECTIVE: This study was performed to introduce an easy method of surgical smoke evacuation for patients with confirmed or suspected COVID-19 undergoing emergency surgery. METHODS: An easy,...
32,922,366
Front Endocrinol (Lausanne)
Body Mass Index and Prognosis of COVID-19 Infection. A Systematic Review.
A better understanding of the SARS-CoV-2 virus behavior and possible risk factors implicated in poor outcome has become an urgent need. We performed a systematic review in order to investigate a possible association between body weight and prognosis among patients diagnosed with COVID-19. We searched in Cochrane Librar...
covid-19;sars-cov-2;body mass index;obesity;risk factor
Systematic Review
Peres, Karina Colombera;Riera, Rachel;Martimbianco, Ana Luiza Cabrera;Ward, Laura Sterian;Cunha, Lucas Leite
10.3389/fendo.2020.00562
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Body Mass Index and Prognosis of COVID-19 Infection. A Systematic Review. [Abstract]: A better understanding of the SARS-CoV-2 virus behavior and possible risk factors implicated in poor outcome has become an urgent need. We performed a systematic review in order to investigate a possible association between b...
32,783,802
J Med Microbiol
Epidemiological and clinical characteristics of coronavirus disease (COVID-19) cases at a screening clinic during the early outbreak period: a single-centre study.
Introduction. Coronavirus disease 2019 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Corona Virus-2 (SARS-CoV-2). The disease was first identified in December 2019 in Wuhan, the capital of China's Hubei province, and has since spread globally, resulting in the ongoing 2019-2020 corona virus pan...
covid-19;rt-pcr;severe acute respiratory syndrome-related coronavirus 2
Journal Article
Khan, Maria;Khan, Haris;Khan, Shehriyar;Nawaz, Maimoona
10.1099/jmm.0.001231
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Epidemiological and clinical characteristics of coronavirus disease (COVID-19) cases at a screening clinic during the early outbreak period: a single-centre study. [Abstract]: Introduction. Coronavirus disease 2019 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Corona Virus-2 (SARS-CoV-...
32,738,691
Sci Total Environ
Influence of Chinese New Year overlapping COVID-19 lockdown on HONO sources in Shijiazhuang.
Nitrous acid (HONO) is an important precursor of hydroxyl radical (OH) in the atmosphere. It is also toxic to human health. In this work, HONO concentrations were measured in Shijiazhuang using a Monitor for AeRosols and Gases in ambient Air (MARGA) from December 15, 2019 to March 15, 2020, which covered the heavy air ...
anthropogenic activities;covid-19;concentrations and sources;heterogeneous conversion;nitrous acid
Journal Article
Liu, Yongchun;Ni, Shuangying;Jiang, Tao;Xing, Shubin;Zhang, Yusheng;Bao, Xiaolei;Feng, Zeming;Fan, Xiaolong;Zhang, Liang;Feng, Haibo
10.1016/j.scitotenv.2020.141025
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Influence of Chinese New Year overlapping COVID-19 lockdown on HONO sources in Shijiazhuang. [Abstract]: Nitrous acid (HONO) is an important precursor of hydroxyl radical (OH) in the atmosphere. It is also toxic to human health. In this work, HONO concentrations were measured in Shijiazhuang using a Monitor fo...
33,033,851
Cancer Immunol Immunother
Immune reconstitution and clinical recovery following anti-CD28 antibody (TGN1412)-induced cytokine storm.
Cytokine storm can result from cancer immunotherapy or certain infections, including COVID-19. Though short-term immune-related adverse events are routinely described, longer-term immune consequences and sequential immune monitoring are not as well defined. In 2006, six healthy volunteers received TGN1412, a CD28 super...
cytokine release syndrome;cytokine storm;immune monitoring;immune-related adverse events (iraes);immunotherapy;tgn1412
Clinical Trial;Journal Article
Panoskaltsis, Nicki;McCarthy, Neil E;Stagg, Andrew J;Mummery, Catherine J;Husni, Mariwan;Arebi, Naila;Greenstein, David;Price, Claire L;Al-Hassi, Hafid O;Koutinas, Michalis;Mantalaris, Athanasios;Knight, Stella C
10.1007/s00262-020-02725-2
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Immune reconstitution and clinical recovery following anti-CD28 antibody (TGN1412)-induced cytokine storm. [Abstract]: Cytokine storm can result from cancer immunotherapy or certain infections, including COVID-19. Though short-term immune-related adverse events are routinely described, longer-term immune conse...
32,647,884
J Neuropathol Exp Neurol
Emergent Viral Infections of the CNS.
Biological evolution of the microbiome continually drives the emergence of human viral pathogens, a subset of which attack the nervous system. The sheer number of pathogens that have appeared, along with their abundance in the environment, demand our attention. For the most part, our innate and adaptive immune systems ...
emergent viral infection;evolution;microbiome;viral encephalitis
Journal Article;Review
Wiley, Clayton A
10.1093/jnen/nlaa054
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Emergent Viral Infections of the CNS. [Abstract]: Biological evolution of the microbiome continually drives the emergence of human viral pathogens, a subset of which attack the nervous system. The sheer number of pathogens that have appeared, along with their abundance in the environment, demand our attention....
33,069,469
Sci Total Environ
Detection of SARS-CoV-2 RNA on public surfaces in a densely populated urban area of Brazil: A potential tool for monitoring the circulation of infected patients.
The world is experiencing the worst global health crisis in recent decades since December/2019 due to a new pandemic coronavirus. The COVID-19 disease, caused by SARS-CoV-2, has resulted in more than 30 million cases and 950 thousand deaths worldwide as of September 21, 2020. Determining the extent of the virus on publ...
covid-19;coronavirus;environment surveillance;genome detection
Journal Article
Abrahao, Jonatas Santos;Sacchetto, Livia;Rezende, Izabela Mauricio;Rodrigues, Rodrigo Araujo Lima;Crispim, Ana Paula Correia;Moura, Cesar;Mendonca, Diogo Correa;Reis, Erik;Souza, Fernanda;Oliveira, Gabriela Fernanda Garcia;Domingos, Iago;de Miranda Boratto, Paulo Victor;Silva, Pedro Henrique Bastos;Queiroz, Victoria Fu...
10.1016/j.scitotenv.2020.142645
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Detection of SARS-CoV-2 RNA on public surfaces in a densely populated urban area of Brazil: A potential tool for monitoring the circulation of infected patients. [Abstract]: The world is experiencing the worst global health crisis in recent decades since December/2019 due to a new pandemic coronavirus. The COV...
32,949,663
J Virol Methods
Value of swab types and collection time on SARS-COV-2 detection using RT-PCR assay.
OBJECTIVE: Low viral load from patients infected with SARS-CoV-2 during infection late stage easily lead to false negative nucleic acid testing results, thus having great challenges to the prevention and control of the current pandemic. In present study, we mainly aimed to evaluate specimen types and specimen collectio...
collection timepoint;positive detection rate;rt-pcr;sars-cov-2;specimen types
Journal Article;Research Support, Non-U.S. Gov't
Liu, Min;Li, Qianyuan;Zhou, Jun;Ai, Wen;Zheng, Xiaoling;Zeng, Jingjing;Liu, Yuwen;Xiang, Xiying;Guo, Rong;Li, Xiaoyin;Wu, Xiandi;Xu, Haiying;Jiang, Ling;Zhang, Huaqin;Chen, Jing;Tian, Lili;Luo, Jun;Luo, Chunhua
10.1016/j.jviromet.2020.113974
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Value of swab types and collection time on SARS-COV-2 detection using RT-PCR assay. [Abstract]: OBJECTIVE: Low viral load from patients infected with SARS-CoV-2 during infection late stage easily lead to false negative nucleic acid testing results, thus having great challenges to the prevention and control of ...
32,462,719
JPEN J Parenter Enteral Nutr
Nutrition Therapy in Critically Ill Patients With Coronavirus Disease 2019.
In the midst of a coronavirus disease 2019 (COVID-19) pandemic, a paucity of data precludes derivation of COVID-19-specific recommendations for nutrition therapy. Until more data are available, focus must be centered on principles of critical care nutrition modified for the constraints of this disease process, ie, COVI...
ards;covid-19;enteral nutrition;nutrition ecmo;nutrition support teams;parenteral nutrition;sepsis
Journal Article;Review
Martindale, Robert;Patel, Jayshil J;Taylor, Beth;Arabi, Yaseen M;Warren, Malissa;McClave, Stephen A
10.1002/jpen.1930
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Nutrition Therapy in Critically Ill Patients With Coronavirus Disease 2019. [Abstract]: In the midst of a coronavirus disease 2019 (COVID-19) pandemic, a paucity of data precludes derivation of COVID-19-specific recommendations for nutrition therapy. Until more data are available, focus must be centered on pri...
32,230,995
Int J Environ Res Public Health
Quarantine Vehicle Scheduling for Transferring High-Risk Individuals in Epidemic Areas.
In a large-scale epidemic outbreak, there can be many high-risk individuals to be transferred for medical isolation in epidemic areas. Typically, the individuals are scattered across different locations, and available quarantine vehicles are limited. Therefore, it is challenging to efficiently schedule the vehicles to ...
epidemics;medical isolation;optimization;public health emergencies;vehicle scheduling;water wave optimization (wwo)
Journal Article;Research Support, Non-U.S. Gov't
Zhang, Min-Xia;Yan, Hong-Fan;Wu, Jia-Yu;Zheng, Yu-Jun
10.3390/ijerph17072275
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Quarantine Vehicle Scheduling for Transferring High-Risk Individuals in Epidemic Areas. [Abstract]: In a large-scale epidemic outbreak, there can be many high-risk individuals to be transferred for medical isolation in epidemic areas. Typically, the individuals are scattered across different locations, and ava...
32,807,565
J Arthroplasty
Public Perceptions of Resuming Elective Surgery During the COVID-19 Pandemic.
BACKGROUND: Many U.S. health systems are grappling with how to safely resume elective surgery amid the COVID-19 pandemic. We used online crowdsourcing to explore public perceptions and concerns toward resuming elective surgery during the pandemic, and to determine factors associated with the preferred timing of surgery...
covid-19;elective care;elective surgery;patient concerns;public perceptions
Journal Article
Moverman, Michael A;Puzzitiello, Richard N;Pagani, Nicholas R;Barnes, C Lowry;Jawa, Andrew;Menendez, Mariano E
10.1016/j.arth.2020.07.037
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Public Perceptions of Resuming Elective Surgery During the COVID-19 Pandemic. [Abstract]: BACKGROUND: Many U.S. health systems are grappling with how to safely resume elective surgery amid the COVID-19 pandemic. We used online crowdsourcing to explore public perceptions and concerns toward resuming elective su...
32,649,272
J Am Coll Nutr
Combating COVID-19 and Building Immune Resilience: A Potential Role for Magnesium Nutrition?
Background: In December 2019, the viral pandemic of respiratory illness caused by COVID-19 began sweeping its way across the globe. Several aspects of this infectious disease mimic metabolic events shown to occur during latent subclinical magnesium deficiency. Hypomagnesemia is a relatively common clinical occurrence t...
covid-19;magnesium;coronavirus;cytokine;hypokalemia;hypomagnesemia;inflammation;nutrition;potassium;vitamin d
Journal Article;Review
Wallace, Taylor C
10.1080/07315724.2020.1785971
[ 1, 0, 1, 1, 0, 0, 0 ]
[Title]: Combating COVID-19 and Building Immune Resilience: A Potential Role for Magnesium Nutrition? [Abstract]: Background: In December 2019, the viral pandemic of respiratory illness caused by COVID-19 began sweeping its way across the globe. Several aspects of this infectious disease mimic metabolic events shown to...
32,828,137
Am J Trop Med Hyg
Accelerating Clinical Evaluation of Repurposed Combination Therapies for COVID-19.
As the global COVID-19 pandemic continues, unabated and clinical trials demonstrate limited effective pharmaceutical interventions, there is a pressing need to accelerate treatment evaluations. Among options for accelerated development is the evaluation of drug combinations in the absence of prior monotherapy data. Thi...
Journal Article
Rayner, Craig R;Dron, Louis;Park, Jay J H;Decloedt, Eric H;Cotton, Mark F;Niranjan, Vis;Smith, Patrick F;Dodds, Michael G;Brown, Fran;Reis, Gilmar;Wesche, David;Mills, Edward J
10.4269/ajtmh.20-0995
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Accelerating Clinical Evaluation of Repurposed Combination Therapies for COVID-19. [Abstract]: As the global COVID-19 pandemic continues, unabated and clinical trials demonstrate limited effective pharmaceutical interventions, there is a pressing need to accelerate treatment evaluations. Among options for acce...
32,711,946
Br J Oral Maxillofac Surg
Evaluation of remote OMFS assessments in the era of pandemic COVID-19 control measures.
Pandemic COVID-19 has put unprecedented pressure on NHS providers to offer non face-to-face consultation. This study aims to assess acceptability of patients and clinicians towards teleconsultation in oral and maxillofacial surgery compared with an expected face-to-face assessment. 340 telephone clinic patient episodes...
innovation;risk management;satisfaction;telecommunication
Journal Article
Cronin, A J;Lopez, J T J;Pabla, R
10.1016/j.bjoms.2020.07.010
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Evaluation of remote OMFS assessments in the era of pandemic COVID-19 control measures. [Abstract]: Pandemic COVID-19 has put unprecedented pressure on NHS providers to offer non face-to-face consultation. This study aims to assess acceptability of patients and clinicians towards teleconsultation in oral and m...
32,681,933
Clin Chim Acta
The diagnostic and prognostic role of myocardial injury biomarkers in hospitalized patients with COVID-19.
OBJECTIVE: The aim of this study was to systematically and comprehensively evaluate the diagnostic and prognostic value of myocardial injury biomarkers in COVID-19 patients. METHODS: This is a retrospective cohort study of confirmed COVID-19 patients that were admitted to the Renmin Hospital of Wuhan University from Ja...
covid-19;in-hospital mortality;myocardial injury biomarkers
Journal Article
Deng, Pingji;Ke, Zunqiong;Ying, Binwu;Qiao, Bin;Yuan, Leyong
10.1016/j.cca.2020.07.018
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: The diagnostic and prognostic role of myocardial injury biomarkers in hospitalized patients with COVID-19. [Abstract]: OBJECTIVE: The aim of this study was to systematically and comprehensively evaluate the diagnostic and prognostic value of myocardial injury biomarkers in COVID-19 patients. METHODS: This is a...
32,491,116
Rev Saude Publica
A brief-review of the risk factors for covid-19 severity.
The World Health Organization has emphasized that one of the most important questions to address regarding the covid-19 pandemic is to understand risk factors for disease severity. We conducted a brief review that synthesizes the available evidence and provides a judgment on the consistency of the association between r...
Journal Article;Review
Rod, J E;Oviedo-Trespalacios, Oscar;Cortes-Ramirez, Javier
10.11606/s1518-8787.2020054002481
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: A brief-review of the risk factors for covid-19 severity. [Abstract]: The World Health Organization has emphasized that one of the most important questions to address regarding the covid-19 pandemic is to understand risk factors for disease severity. We conducted a brief review that synthesizes the available e...
32,355,435
Commun Nonlinear Sci Numer Simul
Mathematical modeling of the spread of the coronavirus disease 2019 (COVID-19) taking into account the undetected infections. The case of China.
In this paper we develop a mathematical model for the spread of the coronavirus disease 2019 (COVID-19). It is a new theta-SEIHRD model (not a SIR, SEIR or other general purpose model), which takes into account the known special characteristics of this disease, as the existence of infectious undetected cases and the di...
covid-19;coronavirus;mathematical model;numerical simulation;pandemic;parameter estimation;sars-cov-2;theta-seihrd model
Journal Article
Ivorra, B;Ferrandez, M R;Vela-Perez, M;Ramos, A M
10.1016/j.cnsns.2020.105303
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Mathematical modeling of the spread of the coronavirus disease 2019 (COVID-19) taking into account the undetected infections. The case of China. [Abstract]: In this paper we develop a mathematical model for the spread of the coronavirus disease 2019 (COVID-19). It is a new theta-SEIHRD model (not a SIR, SEIR o...
32,818,515
Math Biosci
Could masks curtail the post-lockdown resurgence of COVID-19 in the US?
The community lockdown measures implemented in the United States from late March to late May of 2020 resulted in a significant reduction in the community transmission of the COVID-19 pandemic throughout the country. However, a number of US states are currently experiencing an alarming post-lockdown resurgence of the pa...
community lockdown lifting;diagnostic testing and detection contact tracing;face mask compliance;mathematical model for covid-19;self-isolation
Journal Article;Research Support, Non-U.S. Gov't;Research Support, U.S. Gov't, Non-P.H.S.
Ngonghala, Calistus N;Iboi, Enahoro A;Gumel, Abba B
10.1016/j.mbs.2020.108452
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Could masks curtail the post-lockdown resurgence of COVID-19 in the US? [Abstract]: The community lockdown measures implemented in the United States from late March to late May of 2020 resulted in a significant reduction in the community transmission of the COVID-19 pandemic throughout the country. However, a ...
32,525,973
J Clin Endocrinol Metab
Approach to the Patient With Thyrotoxicosis Using Telemedicine.
CONTEXT: The potential for endocrine care via telemedicine has been recognized since the early 2000s when clinical outcome data demonstrated improvements in glycemic control with telemedicine. The widespread use of telemedicine during the COVID-19 pandemic has pushed telemedicine beyond diabetes care and into clinical ...
hyperthyroidism;telehealth;telemedicine;thyrotoxicosis
Case Reports;Journal Article
Griffith, Michelle L;Bischoff, Lindsay A;Baum, Howard B A
10.1210/clinem/dgaa373
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Approach to the Patient With Thyrotoxicosis Using Telemedicine. [Abstract]: CONTEXT: The potential for endocrine care via telemedicine has been recognized since the early 2000s when clinical outcome data demonstrated improvements in glycemic control with telemedicine. The widespread use of telemedicine during ...
32,531,181
Acta Clin Belg
Immersion in an emergency department triage center during the Covid-19 outbreak: first report of the Liege University hospital experience.
OBJECTIVES: Since the beginning of the novel coronavirus outbreak, different strategies have been explored to stem the spread of the disease and appropriately manage patient flow. Triage, an effective solution proposed in disaster medicine, also works well to manage Emergency Department (ED) flow. The aim of this study...
emergency department;novel coronavirus;pandemic;triage
Journal Article
Gilbert, Allison;Brasseur, Edmond;Petit, Meredith;Donneau, Anne Francoise;Diep, AnhNguyet;Hetzel Campbell, Suzanne;Servotte, Jean-Christophe;Piazza, Justine;Ancion, Aurore;Gensburger, Mathieu;D'Orio, Vincent;Ghuysen, Alexandre
10.1080/17843286.2020.1778348
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Immersion in an emergency department triage center during the Covid-19 outbreak: first report of the Liege University hospital experience. [Abstract]: OBJECTIVES: Since the beginning of the novel coronavirus outbreak, different strategies have been explored to stem the spread of the disease and appropriately m...
32,525,368
Psychol Trauma
Dying in the face of the COVID-19 pandemic: Contextual considerations and clinical recommendations.
Dying is a natural part of life; however, death is often a fearful, frightening event. Dying in the midst of the COVID-19 pandemic presents challenges that magnify normative fears and may interfere with a healthy grieving process. To maintain a resilient spirit among those who are at risk of losing a loved one or who h...
Journal Article
LeRoy, Angie S;Robles, Barbara;Kilpela, Lisa S;Garcini, Luz M
10.1037/tra0000818
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Dying in the face of the COVID-19 pandemic: Contextual considerations and clinical recommendations. [Abstract]: Dying is a natural part of life; however, death is often a fearful, frightening event. Dying in the midst of the COVID-19 pandemic presents challenges that magnify normative fears and may interfere w...
32,903,303
Kidney Dis (Basel)
Aggressive Quarantine Measures Reduce the High Morbidity of COVID-19 in Patients on Maintenance Hemodialysis and Medical Staff of Hemodialysis Facilities in Wuhan, China.
Introduction: Maintenance hemodialysis (MHD) patients are highly vulnerable to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Medical staff of dialysis facilities without sufficient biosecurity protection are susceptible once exposed to asymptomatic coronavirus disease 2019 (COVID-19) patients....
covid-19;infection;maintenance hemodialysis;quarantine;sars-cov-2
Journal Article
Li, Junhua;Yang, Yi;Gong, Meiling;Shi, Jia;Zhou, Xi;Xing, Xue;Pan, Hao;Guo, Shuiming;Chang, Xiaoyan;Cheng, Anying;Wang, Yanan;Ge, Shuwang;Xiao, Fang;Yao, Ying;Ning, Yong;He, Fan;Xu, Gang
10.1159/000508579
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Aggressive Quarantine Measures Reduce the High Morbidity of COVID-19 in Patients on Maintenance Hemodialysis and Medical Staff of Hemodialysis Facilities in Wuhan, China. [Abstract]: Introduction: Maintenance hemodialysis (MHD) patients are highly vulnerable to severe acute respiratory syndrome coronavirus 2 (...
33,011,966
Int J Gynaecol Obstet
Risk factors for adverse outcomes among pregnant and postpartum women with acute respiratory distress syndrome due to COVID-19 in Brazil.
OBJECTIVE: To evaluate whether clinical and social risk factors are associated with negative outcomes for COVID-19 disease among Brazilian pregnant and postpartum women. METHODS: A secondary analysis was conducted of the official Acute Respiratory Syndrome Surveillance System database. Pregnant and postpartum women dia...
covid-19;health services accessibility;health status indicators;maternal death
Journal Article
Menezes, Mariane O;Takemoto, Maira L S;Nakamura-Pereira, Marcos;Katz, Leila;Amorim, Melania M R;Salgado, Heloisa O;Melo, Adriana;Diniz, Carmen S G;de Sousa, Liduina A R;Magalhaes, Claudia G;Knobel, Roxana;Andreucci, Carla B
10.1002/ijgo.13407
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Risk factors for adverse outcomes among pregnant and postpartum women with acute respiratory distress syndrome due to COVID-19 in Brazil. [Abstract]: OBJECTIVE: To evaluate whether clinical and social risk factors are associated with negative outcomes for COVID-19 disease among Brazilian pregnant and postpartu...
32,660,339
Otolaryngol Head Neck Surg
Intranasal Antiviral Drug Delivery and Coronavirus Disease 2019 (COVID-19): A State of the Art Review.
OBJECTIVE: To provide a state of the art review of intranasal antiviral drug delivery and to discuss current applications, adverse reactions, and future considerations in the management of coronavirus disease 2019 (COVID-19). DATA SOURCES: PubMed, Embase, and Clinicaltrials.gov search engines. REVIEW METHODS: A structu...
covid-19;antiviral agents;coronavirus;nasal;nasopharynx;otolaryngology;public health;severe acute respiratory syndrome coronavirus 2
Journal Article;Review
Higgins, Thomas S;Wu, Arthur W;Illing, Elisa A;Sokoloski, Kevin J;Weaver, Bree A;Anthony, Benjamin P;Hughes, Nathan;Ting, Jonathan Y
10.1177/0194599820933170
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Intranasal Antiviral Drug Delivery and Coronavirus Disease 2019 (COVID-19): A State of the Art Review. [Abstract]: OBJECTIVE: To provide a state of the art review of intranasal antiviral drug delivery and to discuss current applications, adverse reactions, and future considerations in the management of coronav...
33,027,455
Rev Assoc Med Bras (1992)
Is the COVID-19 disease associated with de novo nephritic syndrome?
INTRODUCTION: This study aims to determine the incidence of de novo nephritic syndrome (NS) in COVID-19 patients and identify its associated factors. METHODS: All ward patients with COVID-19 pneumonia were investigated. After determining the inclusion and exclusion criteria, the study population was identified. The uri...
Journal Article
Dheir, Hamad;Sipahi, Savas;Yaylaci, Selcuk;Genc, Ahmed Cihad;Genc, Fevziye Turkoglu;Genc, Ahmed Bilal;Guclu, Ertugrul;Muratdagi, Gurkan;Toptan, Hande;Karabay, Oguz
10.1590/1806-9282.66.9.1258
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Is the COVID-19 disease associated with de novo nephritic syndrome? [Abstract]: INTRODUCTION: This study aims to determine the incidence of de novo nephritic syndrome (NS) in COVID-19 patients and identify its associated factors. METHODS: All ward patients with COVID-19 pneumonia were investigated. After deter...
32,836,625
Appl Organomet Chem
Quantum dots as a promising agent to combat COVID-19.
Approximately every 100 years, as witnessed in the last two centuries, we are facing an influenza pandemic, necessitating the need to combat a novel virus strain. As a result of the new coronavirus (severe acute respiratory syndrome coronavirus type 2 [SARS-CoV-2] outbreak in January 2020, many clinical studies are bei...
sars-cov-2;antivirals;influenza pandemic;nanomaterials;quantum dots
Journal Article;Review
Manivannan, Selvambigai;Ponnuchamy, Kumar
10.1002/aoc.5887
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Quantum dots as a promising agent to combat COVID-19. [Abstract]: Approximately every 100 years, as witnessed in the last two centuries, we are facing an influenza pandemic, necessitating the need to combat a novel virus strain. As a result of the new coronavirus (severe acute respiratory syndrome coronavirus ...
32,736,959
Int J Drug Policy
The impact of COVID-19 restrictions on needle and syringe programme provision and coverage in England.
BACKGROUND: The restrictions introduced in response to COVID-19 present many challenges, particularly for vulnerable and marginalised populations. These include maintaining access to Needle and Syringe Programmes (NSPs) to reduce the harms associated with injecting drugs. NSPs effectiveness is coverage dependent, but l...
Journal Article;Research Support, Non-U.S. Gov't
Whitfield, Mark;Reed, Howard;Webster, Jane;Hope, Vivian
10.1016/j.drugpo.2020.102851
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The impact of COVID-19 restrictions on needle and syringe programme provision and coverage in England. [Abstract]: BACKGROUND: The restrictions introduced in response to COVID-19 present many challenges, particularly for vulnerable and marginalised populations. These include maintaining access to Needle and Sy...
32,804,760
Clin Nucl Med
Images of COVID-19 Infection Cases in Asymptomatic or Paucisymptomatic Patients With Neoplastic Diseases on 18F-FDG PET/CT.
We describe the results of F-FDG PET/CT of 3 patients referred to our institution during the single day of Monday, March 23, 2020, for an initial assessment of cancer extension or for the therapeutic evaluation of chemotherapy of neoplastic pathology, with no obvious infectious or respiratory symptoms at the time of ex...
Journal Article
Grellier, Jean-Francois;Lussato, David;Guernou, Mohamed;Queneau, Mathieu;Bonardel, Gerald
10.1097/RLU.0000000000003255
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Images of COVID-19 Infection Cases in Asymptomatic or Paucisymptomatic Patients With Neoplastic Diseases on 18F-FDG PET/CT. [Abstract]: We describe the results of F-FDG PET/CT of 3 patients referred to our institution during the single day of Monday, March 23, 2020, for an initial assessment of cancer extensio...
32,662,686
Compr Child Adolesc Nurs
Protecting Children with Long-Term Conditions during the COVID-19 Pandemic.
Emeritus Professor Alan Glasper, from the University of Southampton, discusses what can be done to protect certain groups of children with long-term health conditions from catching SARS-Cov-2 disease caused by the novel coronavirus COVID-19. Furthermore, it is now being reported that a number of children appear to be r...
Editorial
Glasper, Edward Alan
10.1080/24694193.2020.1787772
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Protecting Children with Long-Term Conditions during the COVID-19 Pandemic. [Abstract]: Emeritus Professor Alan Glasper, from the University of Southampton, discusses what can be done to protect certain groups of children with long-term health conditions from catching SARS-Cov-2 disease caused by the novel cor...
32,275,498
Emerg Infect Dis
Severe Acute Respiratory Syndrome Coronavirus 2 Infection among Returnees to Japan from Wuhan, China, 2020.
In early 2020, Japan repatriated 566 nationals from China. Universal laboratory testing and 14-day monitoring of returnees detected 12 cases of severe acute respiratory syndrome coronavirus 2 infection; initial screening results were negative for 5. Common outcomes were remaining asymptomatic (n = 4) and pneumonia (n =...
2019 novel coronavirus disease;asymptomatic infections;covid-19;sars-cov-2;bias;coronavirus disease;pneumonia;prevalence;quarantine;respiratory infections;severe acute respiratory syndrome coronavirus 2;viruses;zoonoses
Journal Article;Research Support, Non-U.S. Gov't
Arima, Yuzo;Shimada, Tomoe;Suzuki, Motoi;Suzuki, Tadaki;Kobayashi, Yusuke;Tsuchihashi, Yuuki;Nakamura, Haruna;Matsumoto, Kaoru;Takeda, Asuka;Kadokura, Keisuke;Sato, Tetsuro;Yahata, Yuichiro;Nakajima, Noriko;Tobiume, Minoru;Takayama, Ikuyo;Kageyama, Tsutomu;Saito, Shinji;Nao, Naganori;Matsui, Tamano;Sunagawa, Tomimasa;H...
10.3201/eid2607.200994
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Severe Acute Respiratory Syndrome Coronavirus 2 Infection among Returnees to Japan from Wuhan, China, 2020. [Abstract]: In early 2020, Japan repatriated 566 nationals from China. Universal laboratory testing and 14-day monitoring of returnees detected 12 cases of severe acute respiratory syndrome coronavirus 2...
32,624,054
Cardiol Young
A teenager with CHD and coronavirus disease 2019.
A 16-year-old girl with history of treated congenital mitral valve disease and signs of respiratory infection was admitted to our paediatric cardiology department. She was tested positive for severe acute respiratory syndrome coronavirus 2. Despite her severe pre-existing cardiac conditions with pulmonary hypertension,...
chd;coronavirus disease 2019;mitral valve stenosis;severe acute respiratory syndrome coronavirus 2
Case Reports;Journal Article
Olfe, Jakob;Grafmann, Maria;Kozlik-Feldmann, Rainer
10.1017/S1047951120002127
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: A teenager with CHD and coronavirus disease 2019. [Abstract]: A 16-year-old girl with history of treated congenital mitral valve disease and signs of respiratory infection was admitted to our paediatric cardiology department. She was tested positive for severe acute respiratory syndrome coronavirus 2. Despite ...
32,707,426
Am J Otolaryngol
Improving protection from bioaerosol exposure during postoperative patient interaction in the COVID-19 era, a quality improvement study.
PURPOSE: During patient transport from operating room to post-operative recovery area, anesthesia staff are at increased risk of particle aerosolization from patients despite wearing face shields. Current single-use face shields do not provide anesthesia staff from adequate protection from bioaerosolized particles expi...
bioaerosolization;covid-19;cough;face shield;patient transport;personal protection equipment;post-operative;sars-cov-2
Journal Article
Ko-Keeney, Ellen H;Saran, Manick S;McLaughlin, Kelly;Lipman, Sidney
10.1016/j.amjoto.2020.102634
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Improving protection from bioaerosol exposure during postoperative patient interaction in the COVID-19 era, a quality improvement study. [Abstract]: PURPOSE: During patient transport from operating room to post-operative recovery area, anesthesia staff are at increased risk of particle aerosolization from pati...
32,431,756
Patient Saf Surg
Introducing the "Corona Curtain": an innovative technique to prevent airborne COVID-19 exposure during emergent intubations.
Background: The coronavirus disease 2019 (COVID-19) pandemic places healthcare workers at risk of exposure to the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Emergency department (ED) staff are particularly vulnerable when managing patients with acute respiratory distress due to the aerosolization of ...
covid-19;coronavirus;intubation;sars-cov-2;viral exposure
Journal Article
Hill, Eric;Crockett, Christopher;Circh, Ryan W;Lansville, Frank;Stahel, Philip F
10.1186/s13037-020-00247-5
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Introducing the "Corona Curtain": an innovative technique to prevent airborne COVID-19 exposure during emergent intubations. [Abstract]: Background: The coronavirus disease 2019 (COVID-19) pandemic places healthcare workers at risk of exposure to the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)...
32,779,813
Phytother Res
Rugosic acid A, derived from Rosa rugosa Thunb., is novel inhibitory agent for NF-kappaB and IL-6/STAT3 axis in acute lung injury model.
Rosa rugosa Thunb., is as a medicinal plant known for anti-diabetic, and anti-inflammatory activities. However, the specific active compounds responsible for the individual pharmacological effects of in R. rugosa extract (95% EtOH) remain unknown. Here, we hypothesized that terpenoid structure, the most abundant consti...
acute pneumonia;il-6;nf-kappab;rosa rugose thunb;rugosic acid a;stat3
Journal Article
Kim, Kang-Hoon;Park, Ye-Ji;Jang, Hyun-Jae;Lee, Seung-Jae;Lee, Soyoung;Yun, Bong-Sik;Lee, Seung Woong;Rho, Mun-Chual
10.1002/ptr.6767
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Rugosic acid A, derived from Rosa rugosa Thunb., is novel inhibitory agent for NF-kappaB and IL-6/STAT3 axis in acute lung injury model. [Abstract]: Rosa rugosa Thunb., is as a medicinal plant known for anti-diabetic, and anti-inflammatory activities. However, the specific active compounds responsible for the ...
33,027,038
J Med Internet Res
How Data Analytics and Big Data Can Help Scientists in Managing COVID-19 Diffusion: Modeling Study to Predict the COVID-19 Diffusion in Italy and the Lombardy Region.
BACKGROUND: COVID-19 is the most widely discussed topic worldwide in 2020, and at the beginning of the Italian epidemic, scientists tried to understand the virus diffusion and the epidemic curve of positive cases with controversial findings and numbers. OBJECTIVE: In this paper, a data analytics study on the diffusion ...
covid-19;italy;sars-cov-2;big data;data analytics;diffusion;modeling;prediction;predictive models
Journal Article;Research Support, Non-U.S. Gov't
Tosi, Davide;Campi, Alessandro
10.2196/21081
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: How Data Analytics and Big Data Can Help Scientists in Managing COVID-19 Diffusion: Modeling Study to Predict the COVID-19 Diffusion in Italy and the Lombardy Region. [Abstract]: BACKGROUND: COVID-19 is the most widely discussed topic worldwide in 2020, and at the beginning of the Italian epidemic, scientists ...
32,589,537
Br J Hosp Med (Lond)
COVID-19 and rheumatology: is shielding really necessary?
Rheumatology patients who are taking immunosuppressants are considered to be at 'high risk' from COVID-19, hence have been self-isolating or shielding. However, they may be protected from the features of hyperinflammation driven by a 'cytokine storm', so may have better clinical outcomes if infected. This editorial dis...
Editorial
Amani, Lisa;Warraich, Rabia;Patel, Nishil;Tahir, Hasan
10.12968/hmed.2020.0284
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 and rheumatology: is shielding really necessary? [Abstract]: Rheumatology patients who are taking immunosuppressants are considered to be at 'high risk' from COVID-19, hence have been self-isolating or shielding. However, they may be protected from the features of hyperinflammation driven by a 'cytoki...
32,701,252
Adv Skin Wound Care
Telemedicine and the COVID-19 Pandemic: Are We Ready to Go Live?
Telemedicine use in the field of wound care had been increasing in popularity when the novel coronavirus 2019 paralyzed the globe in early 2020. To combat the constraints of healthcare delivery during this time, the use of telemedicine has been further expanded. Although many limitations of telemedicine are still being...
Case Reports;Journal Article;Review
Mills, Emily C;Savage, Elizabeth;Lieder, Jessica;Chiu, Ernest S
10.1097/01.ASW.0000669916.01793.93
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Telemedicine and the COVID-19 Pandemic: Are We Ready to Go Live? [Abstract]: Telemedicine use in the field of wound care had been increasing in popularity when the novel coronavirus 2019 paralyzed the globe in early 2020. To combat the constraints of healthcare delivery during this time, the use of telemedicin...
32,755,835
Diabetes Metab Syndr
SARS-CoV-2-host dynamics: Increased risk of adverse outcomes of COVID-19 in obesity.
BACKGROUND AND AIM: The pandemic of COVID-19 has put forward the public health system across countries to prepare themselves for the unprecedented outbreak of the present time. Recognition of the associated risks of morbidity and mortality becomes not only imperative but also fundamental to determine the prevention str...
covid-19;obesity;sars-cov-2
Journal Article;Review
Yadav, Rakhee;Aggarwal, Sandeep;Singh, Archna
10.1016/j.dsx.2020.07.030
[ 1, 1, 1, 0, 0, 0, 0 ]
[Title]: SARS-CoV-2-host dynamics: Increased risk of adverse outcomes of COVID-19 in obesity. [Abstract]: BACKGROUND AND AIM: The pandemic of COVID-19 has put forward the public health system across countries to prepare themselves for the unprecedented outbreak of the present time. Recognition of the associated risks o...
32,759,504
J Clin Invest
Complement and tissue factor-enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis.
Emerging data indicate that complement and neutrophils contribute to the maladaptive immune response that fuels hyperinflammation and thrombotic microangiopathy, thereby increasing coronavirus 2019 (COVID-19) mortality. Here, we investigated how complement interacts with the platelet/neutrophil extracellular traps (NET...
covid-19;complement;immunology;neutrophils;thrombosis
Clinical Trial;Journal Article;Research Support, Non-U.S. Gov't
Skendros, Panagiotis;Mitsios, Alexandros;Chrysanthopoulou, Akrivi;Mastellos, Dimitrios C;Metallidis, Simeon;Rafailidis, Petros;Ntinopoulou, Maria;Sertaridou, Eleni;Tsironidou, Victoria;Tsigalou, Christina;Tektonidou, Maria;Konstantinidis, Theocharis;Papagoras, Charalampos;Mitroulis, Ioannis;Germanidis, Georgios;Lambris...
10.1172/JCI141374
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Complement and tissue factor-enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis. [Abstract]: Emerging data indicate that complement and neutrophils contribute to the maladaptive immune response that fuels hyperinflammation and thrombotic microangiopathy, thereby increasing cor...
32,960,639
Nutr Hosp
[Comparison of expert recommendations on clinical nutrition for hospitalized patients with COVID-19].
Introduction: Introduction: in SARS-CoV-2-infected patients nutritional requirements are increased. These patients present symptoms that make food intake and nutrient absorption difficult, therefore involving nutritional risk. On the other hand, acute respiratory complications require prolonged ICU stays, and this pred...
covid-19. terapia nutricional. pandemias. soporte nutricional. requerimientos nutricionales. malnutricion.
Comparative Study;Journal Article
Martinez Rodriguez, Jessica;Roca Fontbona, Maria
10.20960/nh.03194
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: [Comparison of expert recommendations on clinical nutrition for hospitalized patients with COVID-19]. [Abstract]: Introduction: Introduction: in SARS-CoV-2-infected patients nutritional requirements are increased. These patients present symptoms that make food intake and nutrient absorption difficult, therefor...
32,877,961
Semin Thromb Hemost
Hematology Laboratory Abnormalities in Patients with Coronavirus Disease 2019 (COVID-19).
Over the past few months, Coronavirus Disease 2019 (COVID-19) has spread across much of the world leading to a pandemic. Many infected individuals do not experience signs or symptoms, or experience only mild symptoms, whilst a subset experience severe disease, which is often fatal. A number of laboratory tests have bee...
Journal Article;Review
Christensen, Bianca;Favaloro, Emmanuel J;Lippi, Giuseppe;Van Cott, Elizabeth M
10.1055/s-0040-1715458
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Hematology Laboratory Abnormalities in Patients with Coronavirus Disease 2019 (COVID-19). [Abstract]: Over the past few months, Coronavirus Disease 2019 (COVID-19) has spread across much of the world leading to a pandemic. Many infected individuals do not experience signs or symptoms, or experience only mild s...
32,850,610
Front Public Health
Factors Associated With Job Satisfaction of Frontline Medical Staff Fighting Against COVID-19: A Cross-Sectional Study in China.
Purpose: The current research on frontline medical staff in China fighting against COVID-19 has not yet addressed job satisfaction. The purpose of this study is to investigate the job satisfaction of those who were sent to support Hubei province, China, or worked in local designated hospitals, and then analyze the asso...
covid-19;frontline medical staff;influencing factors;job satisfaction;workload
Journal Article
Yu, Xiaoyan;Zhao, Yuxin;Li, Yuxi;Hu, Chao;Xu, Huilan;Zhao, Xianmei;Huang, Jin
10.3389/fpubh.2020.00426
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Factors Associated With Job Satisfaction of Frontline Medical Staff Fighting Against COVID-19: A Cross-Sectional Study in China. [Abstract]: Purpose: The current research on frontline medical staff in China fighting against COVID-19 has not yet addressed job satisfaction. The purpose of this study is to invest...
32,931,734
Cell
A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2.
The coronavirus disease 2019 pandemic has made deployment of an effective vaccine a global health priority. We evaluated the protective activity of a chimpanzee adenovirus-vectored vaccine encoding a prefusion stabilized spike protein (ChAd-SARS-CoV-2-S) in challenge studies with severe acute respiratory syndrome coron...
covid-19;iga;sars-cov-2;t cells;antibody;intranasal;mucosal immunity;pathogenesis;protection;vaccine
Journal Article;Research Support, N.I.H., Extramural
Hassan, Ahmed O;Kafai, Natasha M;Dmitriev, Igor P;Fox, Julie M;Smith, Brittany K;Harvey, Ian B;Chen, Rita E;Winkler, Emma S;Wessel, Alex W;Case, James Brett;Kashentseva, Elena;McCune, Broc T;Bailey, Adam L;Zhao, Haiyan;VanBlargan, Laura A;Dai, Ya-Nan;Ma, Meisheng;Adams, Lucas J;Shrihari, Swathi;Danis, Jonathan E;Gralin...
10.1016/j.cell.2020.08.026
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2. [Abstract]: The coronavirus disease 2019 pandemic has made deployment of an effective vaccine a global health priority. We evaluated the protective activity of a chimpanzee adenovirus-vectored vaccine encoding...
32,812,025
J Antimicrob Chemother
Evaluation of the efficacy of sofosbuvir plus daclatasvir in combination with ribavirin for hospitalized COVID-19 patients with moderate disease compared with standard care: a single-centre, randomized controlled trial.
BACKGROUND: New therapeutic options are urgently needed to tackle the novel coronavirus disease 2019 (COVID-19). Repurposing existing pharmaceuticals provides an immediate treatment opportunity. We assessed the efficacy of sofosbuvir and daclatasvir with ribavirin for treating patients with COVID-19. METHODS: This was ...
Comparative Study;Journal Article;Randomized Controlled Trial;Research Support, Non-U.S. Gov't
Abbaspour Kasgari, Hamideh;Moradi, Siavash;Shabani, Amir Mohammad;Babamahmoodi, Farhang;Davoudi Badabi, Ali Reza;Davoudi, Lotfollah;Alikhani, Ahmad;Hedayatizadeh Omran, Akbar;Saeedi, Majid;Merat, Shahin;Wentzel, Hannah;Garratt, Anna;Levi, Jacob;Simmons, Bryony;Hill, Andrew;Tirgar Fakheri, Hafez
10.1093/jac/dkaa332
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Evaluation of the efficacy of sofosbuvir plus daclatasvir in combination with ribavirin for hospitalized COVID-19 patients with moderate disease compared with standard care: a single-centre, randomized controlled trial. [Abstract]: BACKGROUND: New therapeutic options are urgently needed to tackle the novel cor...
32,853,320
Rev Chilena Infectol
Optimizing RT-PCR detection of SARS-CoV-2 for developing countries using pool testing.
The global shortage of reagents and kits for nucleic acid extraction and molecular detection of SARS-CoV-2 requires new cost-effective strategies for the diagnosis of suspected COVID-19 cases, especially in countries that need to increase detection capacity. Pooled nucleic acid testing has been extensively used as a co...
Journal Article
Farfan, Mauricio J;Torres, Juan P;O'Ryan, Miguel;Olivares, Mauricio;Gallardo, Pablo;Lastra, Jorge;Salas, Carolina
10.4067/s0716-10182020000300276
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Optimizing RT-PCR detection of SARS-CoV-2 for developing countries using pool testing. [Abstract]: The global shortage of reagents and kits for nucleic acid extraction and molecular detection of SARS-CoV-2 requires new cost-effective strategies for the diagnosis of suspected COVID-19 cases, especially in count...
32,667,669
JAMA Intern Med
Risk Factors Associated With Mortality Among Patients With COVID-19 in Intensive Care Units in Lombardy, Italy.
Importance: Many patients with coronavirus disease 2019 (COVID-19) are critically ill and require care in the intensive care unit (ICU). Objective: To evaluate the independent risk factors associated with mortality of patients with COVID-19 requiring treatment in ICUs in the Lombardy region of Italy. Design, Setting, a...
Journal Article;Observational Study;Research Support, Non-U.S. Gov't
Grasselli, Giacomo;Greco, Massimiliano;Zanella, Alberto;Albano, Giovanni;Antonelli, Massimo;Bellani, Giacomo;Bonanomi, Ezio;Cabrini, Luca;Carlesso, Eleonora;Castelli, Gianpaolo;Cattaneo, Sergio;Cereda, Danilo;Colombo, Sergio;Coluccello, Antonio;Crescini, Giuseppe;Forastieri Molinari, Andrea;Foti, Giuseppe;Fumagalli, Ro...
10.1001/jamainternmed.2020.3539
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Risk Factors Associated With Mortality Among Patients With COVID-19 in Intensive Care Units in Lombardy, Italy. [Abstract]: Importance: Many patients with coronavirus disease 2019 (COVID-19) are critically ill and require care in the intensive care unit (ICU). Objective: To evaluate the independent risk factor...