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32,375,922
Disaster Med Public Health Prep
Initial Coronavirus Disease-2019 Closure Strategies Adopted by a Convenience Sample of US School Districts: Directions for Future Research.
School closures are an important strategy to mitigate the impacts of a pandemic. But an optimal approach to transitioning from in-person to distance learning approaches is lacking. We analyzed a convenience sample of public K-12 schools in the early weeks of the COVID-19 pandemic in the United States. This initial snap...
covid-19;infectious disease transmission;mitigation;pandemics;school closure
Letter
Schlegelmilch, Jeff;Douglas, Claire
10.1017/dmp.2020.147
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Initial Coronavirus Disease-2019 Closure Strategies Adopted by a Convenience Sample of US School Districts: Directions for Future Research. [Abstract]: School closures are an important strategy to mitigate the impacts of a pandemic. But an optimal approach to transitioning from in-person to distance learning a...
32,449,187
J Adv Nurs
Willingness of Chinese nurses to practice in Hubei combating the coronavirus disease 2019 epidemic: A cross-sectional study.
AIMS: To investigate the willingness of Chinese nurses to practice in Hubei combating the coronavirus disease 2019 and to explore the associated factors. DESIGN: A cross-sectional survey. METHODS: Clinical nurses were conveniently recruited by an online link in three provinces out of Hubei, including Hunan (Central sou...
covid-19;epidemic;infectious disease;nurses;staffing;willingness
Journal Article
Gan, Xiaoqing;Shi, Zeya;Chair, Sek Ying;Cao, Xi;Wang, Qun
10.1111/jan.14434
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Willingness of Chinese nurses to practice in Hubei combating the coronavirus disease 2019 epidemic: A cross-sectional study. [Abstract]: AIMS: To investigate the willingness of Chinese nurses to practice in Hubei combating the coronavirus disease 2019 and to explore the associated factors. DESIGN: A cross-sect...
32,486,477
Sensors (Basel)
Development of a Portable, Ultra-Rapid and Ultra-Sensitive Cell-Based Biosensor for the Direct Detection of the SARS-CoV-2 S1 Spike Protein Antigen.
One of the key challenges of the recent COVID-19 pandemic is the ability to accurately estimate the number of infected individuals, particularly asymptomatic and/or early-stage patients. We herewith report the proof-of-concept development of a biosensor able to detect the SARS-CoV-2 S1 spike protein expressed on the su...
bioelectric recognition assay (bera);point-of-care (poc);s1 spike protein;membrane engineering;serological assay;severe acute respiratory syndrome-coronavirus 2 (sars-cov-2)
Letter
Mavrikou, Sophie;Moschopoulou, Georgia;Tsekouras, Vasileios;Kintzios, Spyridon
10.3390/s20113121
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Development of a Portable, Ultra-Rapid and Ultra-Sensitive Cell-Based Biosensor for the Direct Detection of the SARS-CoV-2 S1 Spike Protein Antigen. [Abstract]: One of the key challenges of the recent COVID-19 pandemic is the ability to accurately estimate the number of infected individuals, particularly asymp...
32,670,718
Cureus
Coronavirus Disease 2019 (COVID-19)-Associated Thromboembolic Disease: A Report of Three Patients With Pulmonary Embolism.
Coagulopathy and thromboembolic disease, including pulmonary embolism (PE), are reported complications of coronavirus disease 2019 (COVID-19). The mechanism is not fully understood. We present three patients with COVID-19 and concurrent PE.
acute pulmonary embolism;coagulopathy;covid coagulopathy;covid-19;pulmonary embolism (pe);sars-cov-2
Case Reports
Guccione, Jeffrey;Ocazionez, Daniel;Aisenberg, Gabriel;Odisio, Erika
10.7759/cureus.8583
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Coronavirus Disease 2019 (COVID-19)-Associated Thromboembolic Disease: A Report of Three Patients With Pulmonary Embolism. [Abstract]: Coagulopathy and thromboembolic disease, including pulmonary embolism (PE), are reported complications of coronavirus disease 2019 (COVID-19). The mechanism is not fully unders...
32,964,896
J Cardiovasc Surg (Torino)
Effects of COVID-19 pandemic on cardiac surgery practice in 61 Hospitals worldwide: results of a survey.
BACKGROUND: The aim of this study was to investigate the impact of COVID-19 infection on cardiac surgery community and practice. METHODS: A 43-question survey was sent to cardiac surgery centers worldwide. The survey analyzed the prepandemic organization of the center, the center's response to Covid-19 in terms of re-o...
Journal Article
Onorati, Francesco;Myers, Patrick;Bajona, Pietro;Perrotti, Andrea;Mestres, Carlos A;Quintana, Eduard
10.23736/S0021-9509.20.11556-8
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Effects of COVID-19 pandemic on cardiac surgery practice in 61 Hospitals worldwide: results of a survey. [Abstract]: BACKGROUND: The aim of this study was to investigate the impact of COVID-19 infection on cardiac surgery community and practice. METHODS: A 43-question survey was sent to cardiac surgery centers...
32,849,147
Front Psychol
2019 Novel Coronavirus Disease, Crisis, and Isolation.
The highly contagious 2019 novel coronavirus disease (COVID-19) outbreak has not only impacted health systems, economies, and governments, it has also rapidly grown into a global health crisis, which is now threatening the lives of millions of people globally. While, on one hand, medical institutions are critically att...
2019 novel coronavirus disease;coronavirus;crisis;health;isolation;psychology;recommendations;wellbeing
Journal Article
Roychowdhury, Dev
10.3389/fpsyg.2020.01958
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: 2019 Novel Coronavirus Disease, Crisis, and Isolation. [Abstract]: The highly contagious 2019 novel coronavirus disease (COVID-19) outbreak has not only impacted health systems, economies, and governments, it has also rapidly grown into a global health crisis, which is now threatening the lives of millions of ...
32,424,977
PM R
Telemedicine During COVID-19 for Outpatient Sports and Musculoskeletal Medicine Physicians.
INTRODUCTION: The global pandemic due to SARS-CoV-2 has resulted in an expansion of telemedicine. Measures of quality and barriers for rapid use by patients and physicians are not well described. OBJECTIVE: To describe results from a quality improvement initiative during a rapid adoptive phase of telemedicine during th...
Journal Article;Multicenter Study
Tenforde, Adam S;Iaccarino, Mary A;Borgstrom, Haylee;Hefner, Jaye E;Silver, Julie;Ahmed, Marwa;Babu, Ashwin N;Blauwet, Cheri A;Elson, Lauren;Eng, Christine;Kotler, Dana;Homer, Scott;Makovitch, Steven;McInnis, Kelly C;Vora, Ariana;Borg-Stein, Joanne
10.1002/pmrj.12422
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Telemedicine During COVID-19 for Outpatient Sports and Musculoskeletal Medicine Physicians. [Abstract]: INTRODUCTION: The global pandemic due to SARS-CoV-2 has resulted in an expansion of telemedicine. Measures of quality and barriers for rapid use by patients and physicians are not well described. OBJECTIVE: ...
32,574,408
Transpl Infect Dis
Effect of COVID-19 on liver transplantation in Korea.
COVID-19 is now a pandemic with increasing numbers of cases and deaths. In addition to the economic and social damage caused by COVID-19 outbreak prolongation, damage caused by delayed treatment of other diseases such as severe cirrhosis is also serious. We aimed to describe the effect of COVID-19 on the number of live...
Comparative Study;Journal Article
Lee, Jeong-Moo
10.1111/tid.13384
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Effect of COVID-19 on liver transplantation in Korea. [Abstract]: COVID-19 is now a pandemic with increasing numbers of cases and deaths. In addition to the economic and social damage caused by COVID-19 outbreak prolongation, damage caused by delayed treatment of other diseases such as severe cirrhosis is also...
32,878,840
BMJ Case Rep
COVID-19 complicated by hepatic dysfunction in a 28-week pregnant woman.
The COVID-19 outbreak has spread across the globe at an alarming rate. As the pandemic escalates, experience of COVID-19 in pregnant women is accumulating. We present a case of COVID-19 pneumonia in a 28-week pregnant woman with a known low lying placenta. The patient had deranged liver function tests at presentation, ...
infectious diseases;liver disease;obstetrics and gynaecology;pregnancy
Case Reports;Journal Article
Anness, Abigail;Siddiqui, Farah
10.1136/bcr-2020-237007
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: COVID-19 complicated by hepatic dysfunction in a 28-week pregnant woman. [Abstract]: The COVID-19 outbreak has spread across the globe at an alarming rate. As the pandemic escalates, experience of COVID-19 in pregnant women is accumulating. We present a case of COVID-19 pneumonia in a 28-week pregnant woman wi...
32,770,567
Drug Dev Res
Epigallocatechin gallate and theaflavin gallate interaction in SARS-CoV-2 spike-protein central channel with reference to the hydroxychloroquine interaction: Bioinformatics and molecular docking study.
SARS-CoV-2 or COVID-19 pandemic global outbreak created the most unstable situation of human health-economy. In the past two decades different parts of the word experienced smaller or bigger outbreak related to human coronaviruses. The spike glycoproteins of the COVID-19 (similar to SARS-CoV) attach to the angiotensin-...
ace2;patchdock;sars-cov-2 or covid-19;hydroxychloroquine;pandemic global outbreak;spike glycoprotein;tea flavonoids
Journal Article;Research Support, Non-U.S. Gov't
Maiti, Smarajit;Banerjee, Amrita
10.1002/ddr.21730
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Epigallocatechin gallate and theaflavin gallate interaction in SARS-CoV-2 spike-protein central channel with reference to the hydroxychloroquine interaction: Bioinformatics and molecular docking study. [Abstract]: SARS-CoV-2 or COVID-19 pandemic global outbreak created the most unstable situation of human heal...
32,469,258
Ocul Immunol Inflamm
Detection of SARS-CoV-2 in Human Retinal Biopsies of Deceased COVID-19 Patients.
PURPOSE: To report the presence of viral ribonucleic acid (RNA) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human retina in deceased patients with confirmed novel coronavirus disease 2019 (COVID-19). PATIENTS AND METHODS: Fourteen eyes of 14 deceased patients with confirmed COVID-19 disease were ...
ace-2;covid-19;rt-pcr;sars-cov-2;autopsy;retina
Journal Article
Casagrande, Maria;Fitzek, Antonia;Puschel, Klaus;Aleshcheva, Ganna;Schultheiss, Heinz-Peter;Berneking, Laura;Spitzer, Martin S;Schultheiss, Maximilian
10.1080/09273948.2020.1770301
[ 0, 1, 0, 1, 0, 0, 0 ]
[Title]: Detection of SARS-CoV-2 in Human Retinal Biopsies of Deceased COVID-19 Patients. [Abstract]: PURPOSE: To report the presence of viral ribonucleic acid (RNA) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human retina in deceased patients with confirmed novel coronavirus disease 2019 (COVID-...
32,303,480
J Microbiol Immunol Infect
Recommendations for protecting against and mitigating the COVID-19 pandemic in long-term care facilities.
The COVID-19 outbreak has drawn heightened attention from public health scholars researching ways to limit its spread. Much of the research has been focused on minimizing transmission in hospitals and in the general community. However, a particularly vulnerable community that has received relatively little attention is...
covid-19;compartmentalization;enhanced traffic control bundling;long-term care facility;mitigation;pandemic
Journal Article;Review
Yen, Muh-Yong;Schwartz, Jonathan;King, Chwan-Chuen;Lee, Chung-Ming;Hsueh, Po-Ren
10.1016/j.jmii.2020.04.003
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Recommendations for protecting against and mitigating the COVID-19 pandemic in long-term care facilities. [Abstract]: The COVID-19 outbreak has drawn heightened attention from public health scholars researching ways to limit its spread. Much of the research has been focused on minimizing transmission in hospit...
32,778,870
Age Ageing
Association of frailty with mortality in older inpatients with Covid-19: a cohort study.
BACKGROUND: COVID-19 has disproportionately affected older people. OBJECTIVE: The objective of this paper to investigate whether frailty is associated with all-cause mortality in older hospital inpatients, with COVID-19. DESIGN: Cohort study. SETTING: Secondary care acute hospital. PARTICIPANTS: Participants included a...
covid-19;frailty;longitudinal study;mortality;older adults
Journal Article
Aw, Darren;Woodrow, Lauren;Ogliari, Giulia;Harwood, Rowan
10.1093/ageing/afaa184
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Association of frailty with mortality in older inpatients with Covid-19: a cohort study. [Abstract]: BACKGROUND: COVID-19 has disproportionately affected older people. OBJECTIVE: The objective of this paper to investigate whether frailty is associated with all-cause mortality in older hospital inpatients, with...
32,346,790
Eur Radiol
Coronavirus disease 2019 (COVID-19) imaging reporting and data system (COVID-RADS) and common lexicon: a proposal based on the imaging data of 37 studies.
BACKGROUND: In the vast majority of the laboratory-confirmed coronavirus disease 2019 (COVID-19) patients, computed tomography (CT) examinations yield a typical pattern and the sensitivity of this modality has been reported to be 97% in a large-scale study. Structured reporting systems simplify the interpretation and r...
covid-19;coronavirus;diagnosis;pandemics;pneumonia, viral;tomography, x-ray computed
Journal Article;Systematic Review
Salehi, Sana;Abedi, Aidin;Balakrishnan, Sudheer;Gholamrezanezhad, Ali
10.1007/s00330-020-06863-0
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Coronavirus disease 2019 (COVID-19) imaging reporting and data system (COVID-RADS) and common lexicon: a proposal based on the imaging data of 37 studies. [Abstract]: BACKGROUND: In the vast majority of the laboratory-confirmed coronavirus disease 2019 (COVID-19) patients, computed tomography (CT) examinations...
32,918,985
Resuscitation
Predicting intensive care unit admission and death for COVID-19 patients in the emergency department using early warning scores.
AIMS: To identify the most accurate early warning score (EWS) for predicting an adverse outcome in COVID-19 patients admitted to the emergency department (ED). METHODS: In adult consecutive patients admitted (March 1-April 15, 2020) to the ED of a major referral centre for COVID-19, we retrospectively calculated NEWS, ...
covid-19;early warning scores;mews;news;news2;rems;qsofa
Journal Article;Multicenter Study;Observational Study
Covino, Marcello;Sandroni, Claudio;Santoro, Michele;Sabia, Luca;Simeoni, Benedetta;Bocci, Maria Grazia;Ojetti, Veronica;Candelli, Marcello;Antonelli, Massimo;Gasbarrini, Antonio;Franceschi, Francesco
10.1016/j.resuscitation.2020.08.124
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Predicting intensive care unit admission and death for COVID-19 patients in the emergency department using early warning scores. [Abstract]: AIMS: To identify the most accurate early warning score (EWS) for predicting an adverse outcome in COVID-19 patients admitted to the emergency department (ED). METHODS: I...
32,969,012
J Spec Oper Med
Operational K9s in the COVID-19 World.
Severe acute respiratory syndrome coronavirus 2 (SARSCov- 2) is hypothesized to have originated from a spillover event from an animal reservoir. This has raised many questions, with an important one being whether the widely disseminated coronavirus disease 2019 (COVID-19) is transmissible to other animal species. SARS-...
Journal Article
Gray, Bryant O;St George, Dustin;Cativo, Monica;Tagore, Amundeep;Ariyaprakai, Navin;Palmer, Lee E
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Operational K9s in the COVID-19 World. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARSCov- 2) is hypothesized to have originated from a spillover event from an animal reservoir. This has raised many questions, with an important one being whether the widely disseminated coronavirus disease 201...
32,838,106
Hepatol Commun
gamma-Glutamyltransferase Elevations Are Frequent in Patients With COVID-19: A Clinical Epidemiologic Study.
A newly identified coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes the infectious coronavirus disease 2019 (COVID-19), emerged in December 2019 in Wuhan, Hubei Province, China, and now poses a major threat to global public health. Previous studies have observed highly variable al...
ace2;sars-cov-2;cholangiocyte injury;gamma-glutamyltransferase;liver disease
Journal Article
Shao, Tuo;Tong, Yu;Lu, Shushu;Jeyarajan, Andre J;Su, Feifei;Dai, Jianyi;Shi, Jichan;Huang, Jianping;Hu, Chenchan;Wu, Lianpeng;Dai, Xianning;Cheng, Zhimeng;Yan, Jiuliang;Huang, Peng;Tian, Yanzhang;Li, Shasha;Chung, Raymond T;Chen, Dong
10.1002/hep4.1576
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: gamma-Glutamyltransferase Elevations Are Frequent in Patients With COVID-19: A Clinical Epidemiologic Study. [Abstract]: A newly identified coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes the infectious coronavirus disease 2019 (COVID-19), emerged in December 2019 in Wuh...
32,434,339
Cas Lek Cesk
Testing for COVID-19: a few points to remember.
Diagnostic approaches to COVID-19 include clinical history, PCR tests for the presence of SARS-CoV-2 virus and detection of antibodies. By combining these three approaches, the seroprevalence of anti-SARS-CoV-2 antibodies can be examined in healthcare teams. The aim of the study was to examine the seroprevalence of ant...
covid-19;elisa;iga;igg;sars-cov-2;antibody;positive predictive value;rapid test;sensitivity;specificity
Journal Article
Kratka, Zuzana;Luxova, Stepanka;Malickova, Karin;Furst, Tomas;Simkova, Halina
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Testing for COVID-19: a few points to remember. [Abstract]: Diagnostic approaches to COVID-19 include clinical history, PCR tests for the presence of SARS-CoV-2 virus and detection of antibodies. By combining these three approaches, the seroprevalence of anti-SARS-CoV-2 antibodies can be examined in healthcare...
32,519,809
Pediatr Pulmonol
What we know so far about Coronavirus Disease 2019 in children: A meta-analysis of 551 laboratory-confirmed cases.
AIM: To summarize what we know so far about coronavirus disease (COVID-19) in children. METHOD: We searched PubMed, Scientific Electronic Library Online, and Latin American and Caribbean Center on Health Sciences Information from 1 January 2020 to 4 May 2020. We selected randomized trials, observational studies, case s...
covid-19;ct;meta-analysis;severe acute respiratory syndrome coronavirus 2;signs;symptoms
Journal Article;Meta-Analysis;Systematic Review
Zhang, Linjie;Peres, Tyele G;Silva, Marcus V F;Camargos, Paulo
10.1002/ppul.24869
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: What we know so far about Coronavirus Disease 2019 in children: A meta-analysis of 551 laboratory-confirmed cases. [Abstract]: AIM: To summarize what we know so far about coronavirus disease (COVID-19) in children. METHOD: We searched PubMed, Scientific Electronic Library Online, and Latin American and Caribbe...
32,914,973
J Chem Inf Model
What Are the Odds of Finding a COVID-19 Drug from a Lab Repurposing Screen?
Massive drug repurposing (or repositioning) campaigns are trying to find potential antiviral treatments for COVID-19. Many involve experimental or virtual screening of libraries of compounds previously proven safe in humans-"old drugs". In 20 years of these efforts in many other diseases, never has a new therapeutic hy...
Journal Article;Review
Edwards, Aled
10.1021/acs.jcim.0c00861
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: What Are the Odds of Finding a COVID-19 Drug from a Lab Repurposing Screen? [Abstract]: Massive drug repurposing (or repositioning) campaigns are trying to find potential antiviral treatments for COVID-19. Many involve experimental or virtual screening of libraries of compounds previously proven safe in humans...
32,298,473
Hepatology
Clinical Best Practice Advice for Hepatology and Liver Transplant Providers During the COVID-19 Pandemic: AASLD Expert Panel Consensus Statement.
BACKGROUND AND AIMS: Coronavirus disease 2019 (COVID-19), the illness caused by the SARS-CoV-2 virus, is rapidly spreading throughout the world. Hospitals and healthcare providers are preparing for the anticipated surge in critically ill patients, but few are wholly equipped to manage this new disease. The goals of thi...
Journal Article
Fix, Oren K;Hameed, Bilal;Fontana, Robert J;Kwok, Ryan M;McGuire, Brendan M;Mulligan, David C;Pratt, Daniel S;Russo, Mark W;Schilsky, Michael L;Verna, Elizabeth C;Loomba, Rohit;Cohen, David E;Bezerra, Jorge A;Reddy, K Rajender;Chung, Raymond T
10.1002/hep.31281
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Clinical Best Practice Advice for Hepatology and Liver Transplant Providers During the COVID-19 Pandemic: AASLD Expert Panel Consensus Statement. [Abstract]: BACKGROUND AND AIMS: Coronavirus disease 2019 (COVID-19), the illness caused by the SARS-CoV-2 virus, is rapidly spreading throughout the world. Hospital...
33,045,044
Clin Chem
Cardiac Troponin Testing in Patients with COVID-19: A Strategy for Testing and Reporting Results.
BACKGROUND: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that emerged late in 2019 causing COVID-19 (coronavirus disease-2019) may adversely affect the cardiovascular system. Publications from Asia, Europe, and North America have identified cardiac troponin as an important prognostic indicator for p...
covid-19;acute care;cardiac troponin;risk stratification
Journal Article;Research Support, Non-U.S. Gov't;Review
Kavsak, Peter A;Hammarsten, Ola;Worster, Andrew;Smith, Stephen W;Apple, Fred S
10.1093/clinchem/hvaa225
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Cardiac Troponin Testing in Patients with COVID-19: A Strategy for Testing and Reporting Results. [Abstract]: BACKGROUND: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that emerged late in 2019 causing COVID-19 (coronavirus disease-2019) may adversely affect the cardiovascular system. Public...
32,834,587
Chaos Solitons Fractals
Evaluation and prediction of COVID-19 in India: A case study of worst hit states.
In this manuscript, system modeling and identification techniques are applied in developing a prognostic yet deterministic model to forecast the spread of COVID-19 in India. The model is verified with the historical data and a forecast of the spread for 30-days is presented in the 10 most affected states of India. The ...
pandemic;sars-cov-2;system identification
Journal Article
Rafiq, Danish;Suhail, Suhail Ahmad;Bazaz, Mohammad Abid
10.1016/j.chaos.2020.110014
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Evaluation and prediction of COVID-19 in India: A case study of worst hit states. [Abstract]: In this manuscript, system modeling and identification techniques are applied in developing a prognostic yet deterministic model to forecast the spread of COVID-19 in India. The model is verified with the historical d...
33,051,534
Sci Rep
Lack of tocilizumab effect on mortality in COVID19 patients.
Off-label tocilizumab use in COVID-19 patients reflects concern for cytokine release syndrome. Comparison of matched COVID-19 pneumonia patients found elevated IL-6 levels correlated with mortality that did not change with tocilizumab administration. Correlating mortality with increased IL-6 doesn't imply causality how...
Journal Article
Holt, Gregory E;Batra, Mayank;Murthi, Mukunthan;Kambali, Shweta;Santos, Kayo;Bastidas, Maria Virginia Perez;Asif, Huda;Haddadi, Sara;Arias, Sixto;Mirsaeidi, Mehdi
10.1038/s41598-020-74328-x
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Lack of tocilizumab effect on mortality in COVID19 patients. [Abstract]: Off-label tocilizumab use in COVID-19 patients reflects concern for cytokine release syndrome. Comparison of matched COVID-19 pneumonia patients found elevated IL-6 levels correlated with mortality that did not change with tocilizumab adm...
33,015,715
Clin Infect Dis
Temporal, Spatial, and Epidemiologic Relationships of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Gene Cycle Thresholds: A Pragmatic Ambi-directional Observation.
Prospective serial sampling of 70 patients revealed clinically relevant cycle thresholds (Ct) occurring 9, 26, and 36 days after symptom onset. Race, gender, and corticosteroids apparently did not influence RNA positivity. In a retrospective analysis of 180 patients, initial Ct did not correlate with requirements for a...
rna positivity;sars-cov-2;corticosteroids;cycle threshold
Journal Article
Lesho, Emil;Reno, Lisa;Newhart, Donna;Clifford, Robert;Vasylyeva, Olga;Hanna, John;Yu, Stephanie;Bress, Jonathan;Walsh, Edward
10.1093/cid/ciaa1248
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Temporal, Spatial, and Epidemiologic Relationships of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Gene Cycle Thresholds: A Pragmatic Ambi-directional Observation. [Abstract]: Prospective serial sampling of 70 patients revealed clinically relevant cycle thresholds (Ct) occurring 9, 26, and 36 d...
32,905,015
Saudi Pharm J
Current approaches used in treating COVID-19 from a molecular mechanisms and immune response perspective.
Coronavirus disease 2019 (COVID-19), which is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was declared by the World Health Organization (WHO) as a global pandemic on March 11, 2020. SARS-CoV-2 targets the respiratory system, resulting in symptoms such as fever, headache, dry cough,...
ace2, angiotensin-converting enzyme 2;ahfs, american hospital formula service;angii, angiotensin ii;apcs, antigen presenting cells;ards, acute respiratory distress syndrome;covid-19, coronavirus disease;covs, coronaviruses;coronavirus;gvhd, graft versus host disease;hcovs, human coronoaviruses;ibv, infectious bronchiti...
Journal Article;Review
Alnefaie, Alaa;Albogami, Sarah
10.1016/j.jsps.2020.08.024
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Current approaches used in treating COVID-19 from a molecular mechanisms and immune response perspective. [Abstract]: Coronavirus disease 2019 (COVID-19), which is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was declared by the World Health Organization (WHO) as a global p...
32,438,948
CJEM
Just the facts: What drugs are safe and effective for COVID-19?
A 53-year-old male presents with cough, fever, and myalgias for 7 days. Vitals include temperature, 38.0 degrees C; heart rate, 110; blood pressure, 118/70 mm Hg; respiration rate, 28; and oxygen saturation 83% on room air. His only past medical history is hypertension. Your community is in the midst of the coronavirus...
covid-19;medications;therapeutics
Case Reports;Journal Article;Review
Long, Brit;Liang, Stephen Y;Rosenberg, Hans;Hicks, Christopher;Gottlieb, Michael
10.1017/cem.2020.403
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Just the facts: What drugs are safe and effective for COVID-19? [Abstract]: A 53-year-old male presents with cough, fever, and myalgias for 7 days. Vitals include temperature, 38.0 degrees C; heart rate, 110; blood pressure, 118/70 mm Hg; respiration rate, 28; and oxygen saturation 83% on room air. His only pa...
32,395,572
Data Brief
Dataset of Vietnamese student's learning habits during COVID-19.
A dataset was constructed to examine Vietnamese student's learning habits during the time schools were suspended due to the novel coronavirus - SARS-CoV-2 (COVID-19), in response to a call for interdisciplinary research on the potential effects of the coronavirus pandemic (Elsevier, 2020). The questionnaires were sprea...
covid-19;learning habits;occupational aspiration;school closure;secondary school;socioeconomic;vietnam
Journal Article
Trung, Tran;Hoang, Anh-Duc;Nguyen, Trung Tien;Dinh, Viet-Hung;Nguyen, Yen-Chi;Pham, Hiep-Hung
10.1016/j.dib.2020.105682
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Dataset of Vietnamese student's learning habits during COVID-19. [Abstract]: A dataset was constructed to examine Vietnamese student's learning habits during the time schools were suspended due to the novel coronavirus - SARS-CoV-2 (COVID-19), in response to a call for interdisciplinary research on the potenti...
32,799,392
Acta Paediatr
Kawasaki disease or Kawasaki-like disease: influence of SARS-CoV-2 infections in Japan.
The coronavirus disease 2019 (COVID-19) pandemic witnessed several clusters of children with fever and multisystem inflammation resembling Kawasaki disease (KD). Due to the evidence of a preceding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in most of these patients, post-viral immunological ...
japan;kawasaki disease;sars-cov-2
Letter;Observational Study
Iio, Kazuki;Uda, Kazuhiro;Hataya, Hiroshi;Yasui, Fumihiko;Honda, Tomoko;Sanada, Takahiro;Yamaji, Kenzaburo;Kohara, Michinori;Itokawa, Masanari;Miura, Masaru
10.1111/apa.15535
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Kawasaki disease or Kawasaki-like disease: influence of SARS-CoV-2 infections in Japan. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic witnessed several clusters of children with fever and multisystem inflammation resembling Kawasaki disease (KD). Due to the evidence of a preceding severe acute r...
32,347,747
Int Rev Immunol
Can melatonin reduce the severity of COVID-19 pandemic?
The current COVID-19 pandemic is one of the most devastating events in recent history. The virus causes relatively minor damage to young, healthy populations, imposing life-threatening danger to the elderly and people with diseases of chronic inflammation. Therefore, if we could reduce the risk for vulnerable populatio...
apoptosis;bat;covid-19;coronavirus;melatonin;sars-cov-2
Journal Article
Shneider, Alex;Kudriavtsev, Aleksandr;Vakhrusheva, Anna
10.1080/08830185.2020.1756284
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Can melatonin reduce the severity of COVID-19 pandemic? [Abstract]: The current COVID-19 pandemic is one of the most devastating events in recent history. The virus causes relatively minor damage to young, healthy populations, imposing life-threatening danger to the elderly and people with diseases of chronic ...
33,058,321
Eur J Neurol
EAN consensus statement for management of patients with neurological diseases during the COVID-19 pandemic.
BACKGROUND AND PURPOSE: The recent SARS-CoV-2 pandemic has posed multiple challenges to the practice of clinical neurology including recognition of emerging neurological complications and management of coexistent neurological diseases. In a fast-evolving pandemic, evidence-based studies are lacking in many areas. This ...
covid-19;chronic disease;human;neurology;practice guideline
Guideline;Journal Article;Review
von Oertzen, T J;Macerollo, A;Leone, M A;Beghi, E;Crean, M;Oztuk, S;Bassetti, C;Twardzik, A;Bereczki, D;Di Liberto, G;Helbok, R;Oreja-Guevara, C;Pisani, A;Sauerbier, A;Sellner, J;Soffietti, R;Zedde, M;Bianchi, E;Bodini, B;Cavallieri, F;Campiglio, L;Maia, L F;Priori, A;Rakusa, M;Taba, P;Moro, E;Jenkins, T M
10.1111/ene.14521
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: EAN consensus statement for management of patients with neurological diseases during the COVID-19 pandemic. [Abstract]: BACKGROUND AND PURPOSE: The recent SARS-CoV-2 pandemic has posed multiple challenges to the practice of clinical neurology including recognition of emerging neurological complications and man...
32,496,205
J Med Internet Res
Why African Americans Are a Potential Target for COVID-19 Infection in the United States.
Since the World Health Organization declared the coronavirus disease (COVID-19) outbreak a pandemic, significant changes have occurred in the United States as the infection spread reached and passed its exponential phase. A stringent analysis of COVID-19 epidemiologic data requires time and would generally be expected ...
african american;covid-19;coronavirus;infectious disease;minority;mortality;race;virus
Journal Article
Hamidian Jahromi, Alireza;Hamidianjahromi, Anahid
10.2196/19934
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Why African Americans Are a Potential Target for COVID-19 Infection in the United States. [Abstract]: Since the World Health Organization declared the coronavirus disease (COVID-19) outbreak a pandemic, significant changes have occurred in the United States as the infection spread reached and passed its expone...
33,075,636
Mol Immunol
High serum IL-6 values increase the risk of mortality and the severity of pneumonia in patients diagnosed with COVID-19.
The clinical presentation of COVID-19 is very heterogeneous, ranging from asymptomatic to severe, which could lead to the need for mechanical ventilation or even death.We analyzed the serum levels of IL-6 in patients with COVID-19 diagnosis and its relationship with the severity of the disease, the need for mechanical ...
covid-19 pneumonia;curb-65 score;icu admission;il-6 serum levels;mortality;prognostic biomarkers
Journal Article;Research Support, Non-U.S. Gov't
Guirao, Jose J;Cabrera, Carmen M;Jimenez, Natalia;Rincon, Laura;Urra, Jose M
10.1016/j.molimm.2020.10.006
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: High serum IL-6 values increase the risk of mortality and the severity of pneumonia in patients diagnosed with COVID-19. [Abstract]: The clinical presentation of COVID-19 is very heterogeneous, ranging from asymptomatic to severe, which could lead to the need for mechanical ventilation or even death.We analyze...
32,292,839
Adv Radiat Oncol
Prostate Cancer Radiation Therapy Recommendations in Response to COVID-19.
Purpose: During a global pandemic, the benefit of routine visits and treatment of patients with cancer must be weighed against the risks to patients, staff, and society. Prostate cancer is one of the most common cancers radiation oncology departments treat, and efficient resource utilization is essential in the setting...
Journal Article
Zaorsky, Nicholas G;Yu, James B;McBride, Sean M;Dess, Robert T;Jackson, William C;Mahal, Brandon A;Chen, Ronald;Choudhury, Ananya;Henry, Ann;Syndikus, Isabel;Mitin, Timur;Tree, Alison;Kishan, Amar U;Spratt, Daniel E
10.1016/j.adro.2020.03.010
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Prostate Cancer Radiation Therapy Recommendations in Response to COVID-19. [Abstract]: Purpose: During a global pandemic, the benefit of routine visits and treatment of patients with cancer must be weighed against the risks to patients, staff, and society. Prostate cancer is one of the most common cancers radi...
32,938,783
Neurology
Education Research: Effect of the COVID-19 pandemic on neurology trainees in Italy: A resident-driven survey.
OBJECTIVE: To assess the effect of the coronavirus disease 2019 (COVID-19) outbreak on neurology resident training in Italy. METHOD: We created a web-based survey regarding changes in clinical, research, and educational activity of neurology trainees in Italy during the COVID-19 pandemic and the preventive measures und...
Journal Article
Abati, Elena;Costamagna, Gianluca
10.1212/WNL.0000000000010878
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Education Research: Effect of the COVID-19 pandemic on neurology trainees in Italy: A resident-driven survey. [Abstract]: OBJECTIVE: To assess the effect of the coronavirus disease 2019 (COVID-19) outbreak on neurology resident training in Italy. METHOD: We created a web-based survey regarding changes in clini...
32,558,945
J Med Virol
A case series of COVID-19 patients with chronic hepatitis B virus infection.
Previous studies reported that coronavirus disease 2019 (COVID-19) was likely to result in liver injury. However, few studies reported the impacts of COVID-19 on liver function in patients with chronic liver diseases. We aimed to describe a case series of COVID-19 patients with chronic hepatitis B virus (HBV) infection...
chronic hepatitis b;clinical features;coronavirus disease 2019
Journal Article;Research Support, Non-U.S. Gov't
Li, Yang;Li, Chunyang;Wang, Jian;Zhu, Chuanwu;Zhu, Li;Ji, Fang;Liu, Longgen;Xu, Tianmin;Zhang, Biao;Xue, Leyang;Yan, Xiaomin;Huang, Rui;Wu, Chao;Yan, Xuebing
10.1002/jmv.26201
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: A case series of COVID-19 patients with chronic hepatitis B virus infection. [Abstract]: Previous studies reported that coronavirus disease 2019 (COVID-19) was likely to result in liver injury. However, few studies reported the impacts of COVID-19 on liver function in patients with chronic liver diseases. We a...
32,940,922
Laryngoscope
Expression of ACE2 and TMPRSS2 Proteins in the Upper and Lower Aerodigestive Tracts of Rats: Implications on COVID 19 Infections.
OBJECTIVE: Patients with coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), exhibit not only respiratory symptoms but also symptoms of chemo-sensitive disorders. Cellular entry of SARS-CoV-2 depends on the binding of its spike protein to a cellular receptor name...
ace2;covid-19;tmprss2;aerodigestive tract;dysgeusia
Journal Article;Research Support, Non-U.S. Gov't
Sato, Taku;Ueha, Rumi;Goto, Takao;Yamauchi, Akihito;Kondo, Kenji;Yamasoba, Tatsuya
10.1002/lary.29132
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Expression of ACE2 and TMPRSS2 Proteins in the Upper and Lower Aerodigestive Tracts of Rats: Implications on COVID 19 Infections. [Abstract]: OBJECTIVE: Patients with coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), exhibit not only respiratory sympto...
32,362,345
Clin Ther
COVID-19 and Depression.
The COVID-19 pandemic embodies overwhelming stresses-unemployment, death, and isolation, among others. When called upon, clinicians must try to sort out demoralization from depression. This commentary discerns the characteristics of demoralization versus depression, and suggests solutions for both, together with a caut...
covid-19;chloroquine;demoralization;depression;hydroxychloroquine
Journal Article
Shader, Richard I
10.1016/j.clinthera.2020.04.010
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 and Depression. [Abstract]: The COVID-19 pandemic embodies overwhelming stresses-unemployment, death, and isolation, among others. When called upon, clinicians must try to sort out demoralization from depression. This commentary discerns the characteristics of demoralization versus depression, and sug...
32,677,038
Int J Gynaecol Obstet
The impact of COVID-19 on services for people affected by sexual and gender-based violence.
Sexual and gender-based violence (SGBV), and particularly intimate partner violence (IPV), has spiked dramatically during the COVID-19 pandemic. At the same time, the pandemic is impacting and interrupting SGBV and IPV services of all kinds. This paper focuses on the impact of the COVID-19 pandemic on clinical care and...
covid-19;clinical care;domestic violence;forensic examination;intimate partner violence (ipv);sexual and gender-based violence;sexual violence
Journal Article
Johnson, Katy;Green, Lindsey;Volpellier, Muriel;Kidenda, Suzanne;McHale, Thomas;Naimer, Karen;Mishori, Ranit
10.1002/ijgo.13285
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The impact of COVID-19 on services for people affected by sexual and gender-based violence. [Abstract]: Sexual and gender-based violence (SGBV), and particularly intimate partner violence (IPV), has spiked dramatically during the COVID-19 pandemic. At the same time, the pandemic is impacting and interrupting S...
32,275,784
Hepatology
Telemedicine in Liver Disease and Beyond: Can the COVID-19 Crisis Lead to Action?
Evidence strongly supports that access to specialty gastroenterology or hepatology care in cirrhosis is associated with higher adherence to guideline-recommended care and improves clinical outcomes. Presently, only about one half of acute care hospitalizations for cirrhosis-related complications result in inpatient spe...
Journal Article
Serper, Marina;Cubell, Allen W;Deleener, Mary Elisabeth;Casher, Tara K;Rosenberg, Dale J;Whitebloom, Dale;Rosin, Roy M
10.1002/hep.31276
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Telemedicine in Liver Disease and Beyond: Can the COVID-19 Crisis Lead to Action? [Abstract]: Evidence strongly supports that access to specialty gastroenterology or hepatology care in cirrhosis is associated with higher adherence to guideline-recommended care and improves clinical outcomes. Presently, only ab...
32,369,435
Vet Pathol
Canine Respiratory Coronavirus: A Naturally Occurring Model of COVID-19?
Discovered in 2003 at the Royal Veterinary College, London, canine respiratory coronavirus (CRCoV) is a betacoronavirus of dogs and major cause of canine infectious respiratory disease complex. Generally causing mild clinical signs of persistent cough and nasal discharge, the virus is highly infectious and is most prev...
covid-19;sars-cov-2;animal models of human disease;betacoronavirus;canine respiratory coronavirus;dogs;emerging infectious diseases;lung;one health;pathogenesis;tracheal cultures;transmission
Journal Article
Priestnall, Simon L
10.1177/0300985820926485
[ 0, 0, 0, 1, 1, 0, 0 ]
[Title]: Canine Respiratory Coronavirus: A Naturally Occurring Model of COVID-19? [Abstract]: Discovered in 2003 at the Royal Veterinary College, London, canine respiratory coronavirus (CRCoV) is a betacoronavirus of dogs and major cause of canine infectious respiratory disease complex. Generally causing mild clinical ...
32,362,368
J Visc Surg
Antibiotics alone as an alternative to appendectomy for uncomplicated acute appendicitis in adults: Changes in treatment modalities related to the COVID-19 health crisis.
The massive inflow of patients with COVID-19 requiring urgent care has overloaded hospitals in France and impacts the management of other patients. Deferring hospitalization and non-urgent surgeries has become a priority for surgeons today in order to relieve the health care system. It is obviously not simple to reduce...
acute appendicitis;antibiotic therapy;appendectomy;covid-19;coronavirus
Journal Article;Review
Collard, M;Lakkis, Z;Loriau, J;Mege, D;Sabbagh, C;Lefevre, J H;Maggiori, L
10.1016/j.jviscsurg.2020.04.014
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Antibiotics alone as an alternative to appendectomy for uncomplicated acute appendicitis in adults: Changes in treatment modalities related to the COVID-19 health crisis. [Abstract]: The massive inflow of patients with COVID-19 requiring urgent care has overloaded hospitals in France and impacts the management...
32,839,702
Energy Res Soc Sci
The impact of different COVID-19 containment measures on electricity consumption in Europe.
As of March 13, 2020, the director general of the World Health Organization (WHO) considered Europe as the centre of the global COVID-19 outbreak. All countries within Europe had a confirmed case of COVID-19 by March 17. In response to the pandemic, different European countries took different approaches. This paper com...
covid_19;consumer behaviour;coronavirus;european power systems
Journal Article
Bahmanyar, Alireza;Estebsari, Abouzar;Ernst, Damien
10.1016/j.erss.2020.101683
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The impact of different COVID-19 containment measures on electricity consumption in Europe. [Abstract]: As of March 13, 2020, the director general of the World Health Organization (WHO) considered Europe as the centre of the global COVID-19 outbreak. All countries within Europe had a confirmed case of COVID-19...
32,837,723
Clin Case Rep
Occurrence of acute coronary syndrome, pulmonary thromboembolism, and cerebrovascular event in COVID-19.
COVID-19 causes significant hypoxia along with an exacerbated inflammatory milieu, which may be a trigger for atherosclerotic plaque rupture and/or thromboembolic events. Herein, we presented a case of COVID-19 presented with acute coronary syndrome followed by pulmonary thromboembolism and cerebrovascular accident.
covid-19;acute coronary syndrome;acute pulmonary thromboembolism
Case Reports
Jenab, Yaser;Rezaei, Nima;Hedayat, Behnam;Naderian, Mohammadreza;Shirani, Shapour;Hosseini, Kaveh
10.1002/ccr3.3112
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Occurrence of acute coronary syndrome, pulmonary thromboembolism, and cerebrovascular event in COVID-19. [Abstract]: COVID-19 causes significant hypoxia along with an exacerbated inflammatory milieu, which may be a trigger for atherosclerotic plaque rupture and/or thromboembolic events. Herein, we presented a ...
32,665,725
Am J Pharm Educ
Facilitating Wellbeing in a Turbulent Time.
The novel coronavirus 2019 (COVID-19) pandemic has changed the way we live, work, and study. As faculty members, staff members, and students attempt to create and maintain a new normal because of this pandemic, the preservation of wellbeing becomes the responsibility of each and every one of us. The pandemic has taught...
covid-19;faculty;leadership;staff;students;wellbeing
Journal Article
Brazeau, Gayle A;Frenzel, Jeanne E;Prescott, William A Jr
10.5688/ajpe8154
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Facilitating Wellbeing in a Turbulent Time. [Abstract]: The novel coronavirus 2019 (COVID-19) pandemic has changed the way we live, work, and study. As faculty members, staff members, and students attempt to create and maintain a new normal because of this pandemic, the preservation of wellbeing becomes the re...
32,763,356
Toxicol Appl Pharmacol
Formation of lamellar body-like structure may be an initiator of didecyldimethylammonium chloride-induced toxic response.
Due to the pandemic of coronavirus disease 2019, the use of disinfectants is rapidly increasing worldwide. Didecyldimethylammonium chloride (DDAC) is an EPA-registered disinfectant, it was also a component in humidifier disinfectants that had caused idiopathic pulmonary diseases in Korea. In this study, we identified t...
didecyldimethylammonium chloride;disinfectants;idiopathic pulmonary fibrosis;lamella body;matrix metalloproteinase-1;quaternary ammonium compounds
Journal Article;Research Support, Non-U.S. Gov't
Park, Eun-Jung;Seong, Eunsol;Kang, Min-Sung;Lee, Gwang-Hee;Kim, Dong-Wan;Han, Ji-Seok;Lim, Hyun-Ji;Lee, Seung Hyeun;Han, Hyoung-Yun
10.1016/j.taap.2020.115182
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Formation of lamellar body-like structure may be an initiator of didecyldimethylammonium chloride-induced toxic response. [Abstract]: Due to the pandemic of coronavirus disease 2019, the use of disinfectants is rapidly increasing worldwide. Didecyldimethylammonium chloride (DDAC) is an EPA-registered disinfect...
32,336,398
Br J Oral Maxillofac Surg
Precaution of 2019 novel coronavirus infection in department of oral and maxillofacial surgery.
The epidemic of the 2019 novel coronavirus (2019-nCoV) infection has presented as a critical period. Until February 23th 2020, more than 77 000 cases of 2019-nCoV infection have been confirmed in China, which has a great impact on economy and society. It has also interferred with ordinary medical practice of oral and m...
2019 novel coronavirus infection;medical protection;oral and maxillofacial;surgery
Journal Article
Zhao, Zhiguo;Gao, Dan
10.1016/j.bjoms.2020.03.001
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Precaution of 2019 novel coronavirus infection in department of oral and maxillofacial surgery. [Abstract]: The epidemic of the 2019 novel coronavirus (2019-nCoV) infection has presented as a critical period. Until February 23th 2020, more than 77 000 cases of 2019-nCoV infection have been confirmed in China, ...
33,050,590
Int J Environ Res Public Health
The Use of UVC Irradiation to Sterilize Filtering Facepiece Masks Limiting Airborne Cross-Infection.
In addition to looking for effective drugs and a vaccine, which are necessary to save and protect human health, it is also important to limit, or at least to slow, the spread of coronavirus. One important element in this action is the use of individual protective devices such as filtering facepiece masks. Currently, ma...
hepa filter sterilization;sars-cov-2;uvgi;ultraviolet germicidal irradiation
Journal Article;Research Support, Non-U.S. Gov't
Kierat, Wojciech;Augustyn, Weronika;Koper, Piotr;Pawlyta, Miroslawa;Chrusciel, Arkadiusz;Wyrwol, Bernard
10.3390/ijerph17207396
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Use of UVC Irradiation to Sterilize Filtering Facepiece Masks Limiting Airborne Cross-Infection. [Abstract]: In addition to looking for effective drugs and a vaccine, which are necessary to save and protect human health, it is also important to limit, or at least to slow, the spread of coronavirus. One imp...
32,861,856
J Allergy Clin Immunol Pract
Age-Related Differences in Immunological Responses to SARS-CoV-2.
There is a striking age-related disparity in the prevalence and severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced coronavirus disease 2019 infections, which might be explained by age-dependent immunological mechanisms. These include age-related physiological differences in immunological r...
covid-19;pediatric multi-system inflammatory disorder;sars-cov-2
Journal Article;Review
Wong, Lydia Su Yin;Loo, Evelyn Xiu Ling;Kang, Alicia Yi Hui;Lau, Hui Xing;Tambyah, Paul Anantharajah;Tham, Elizabeth Huiwen
10.1016/j.jaip.2020.08.026
[ 1, 0, 1, 1, 0, 0, 0 ]
[Title]: Age-Related Differences in Immunological Responses to SARS-CoV-2. [Abstract]: There is a striking age-related disparity in the prevalence and severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced coronavirus disease 2019 infections, which might be explained by age-dependent immunolog...
32,518,469
Build Environ
Can indoor sports centers be allowed to re-open during the COVID-19 pandemic based on a certificate of equivalence?
Within a time span of only a few months, the SARS-CoV-2 virus has managed to spread across the world. This virus can spread by close contact, which includes large droplet spray and inhalation of microscopic droplets, and by indirect contact via contaminated objects. While in most countries, supermarkets have remained o...
aerodynamics;building ventilation;corona virus;face masks;filters;fitness;gym;sports club
Journal Article
Blocken, B;van Druenen, T;van Hooff, T;Verstappen, P A;Marchal, T;Marr, L C
10.1016/j.buildenv.2020.107022
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Can indoor sports centers be allowed to re-open during the COVID-19 pandemic based on a certificate of equivalence? [Abstract]: Within a time span of only a few months, the SARS-CoV-2 virus has managed to spread across the world. This virus can spread by close contact, which includes large droplet spray and in...
32,645,951
Int J Mol Sci
Implications of SARS-CoV-2 Mutations for Genomic RNA Structure and Host microRNA Targeting.
The SARS-CoV-2 virus is a recently-emerged zoonotic pathogen already well adapted to transmission and replication in humans. Although the mutation rate is limited, recently introduced mutations in SARS-CoV-2 have the potential to alter viral fitness. In addition to amino acid changes, mutations could affect RNA seconda...
rna secondary structure;sars-cov-2;conserved mutation;mirna
Journal Article
Hosseini Rad Sm, Ali;McLellan, Alexander D
10.3390/ijms21134807
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Implications of SARS-CoV-2 Mutations for Genomic RNA Structure and Host microRNA Targeting. [Abstract]: The SARS-CoV-2 virus is a recently-emerged zoonotic pathogen already well adapted to transmission and replication in humans. Although the mutation rate is limited, recently introduced mutations in SARS-CoV-2...
32,846,088
J Chem Inf Model
Protein Surface Printer for Exploring Protein Domains.
The surface of proteins is vital in determining protein functions. Herein, a program, Protein Surface Printer (PSP), is built that performs multiple functions in quantifying protein surface domains. Two proteins, PETase and cytochrome P450, are used to validate that the program supports atomistic simulations with diffe...
Journal Article;Research Support, U.S. Gov't, Non-P.H.S.
Li, Yang;Qiao, Baofu;Olvera de la Cruz, Monica
10.1021/acs.jcim.0c00582
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Protein Surface Printer for Exploring Protein Domains. [Abstract]: The surface of proteins is vital in determining protein functions. Herein, a program, Protein Surface Printer (PSP), is built that performs multiple functions in quantifying protein surface domains. Two proteins, PETase and cytochrome P450, are...
32,835,080
Inform Med Unlocked
A case-based reasoning framework for early detection and diagnosis of novel coronavirus.
Coronavirus, also known as COVID-19, has been declared a pandemic by the World Health Organization (WHO). At the time of conducting this study, it had recorded over 11,301,850 confirmed cases while more than 531,806 have died due to it, with these figures rising daily across the globe. The burden of this highly contagi...
covid-19;case-based reasoning;coronavirus;natural language processing;ontology
Journal Article
Oyelade, Olaide N;Ezugwu, Absalom E
10.1016/j.imu.2020.100395
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: A case-based reasoning framework for early detection and diagnosis of novel coronavirus. [Abstract]: Coronavirus, also known as COVID-19, has been declared a pandemic by the World Health Organization (WHO). At the time of conducting this study, it had recorded over 11,301,850 confirmed cases while more than 53...
32,501,174
J Gerontol Soc Work
COVID-19 Pandemic: Workforce Implications for Gerontological Social Work.
The COVID-19 pandemic has been challenging for people of all ages but particularly devastating to adults 65 and older, which has highlighted the critical need for ensuring that all social workers gain the knowledge and skills necessary to work with this population. While there is a critical shortage of gerontological s...
covid-19;gerontological social work;pandemic;workforce
Journal Article
Berg-Weger, Marla;Schroepfer, Tracy
10.1080/01634372.2020.1772934
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 Pandemic: Workforce Implications for Gerontological Social Work. [Abstract]: The COVID-19 pandemic has been challenging for people of all ages but particularly devastating to adults 65 and older, which has highlighted the critical need for ensuring that all social workers gain the knowledge and skills...
32,378,464
Br J Community Nurs
Long-term conditions and severe acute respiratory syndrome SARS-CoV-2 (COVID-19).
Observation of infection trends through the course of the ongoing COVID-19 pandemic has indicated that those with certain pre-existing chronic conditions, such as hypertension, chronic obstructive pulmonary disease and obesity, are particularly likely to develop severe infection and experience disastrous sequelae, incl...
covid-19;chronic obstructive pulmonary disease;diabetes;hypertension;long-term conditions
Journal Article
Robinson, Patricia
10.12968/bjcn.2020.25.5.247
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Long-term conditions and severe acute respiratory syndrome SARS-CoV-2 (COVID-19). [Abstract]: Observation of infection trends through the course of the ongoing COVID-19 pandemic has indicated that those with certain pre-existing chronic conditions, such as hypertension, chronic obstructive pulmonary disease an...
32,759,645
J Clin Med
COVID-19 and the Kidney: From Epidemiology to Clinical Practice.
The new respiratory infectious disease coronavirus disease 2019 (COVID-19) that originated in Wuhan, China, in December 2019 and caused by a new strain of zoonotic coronavirus, named severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), to date has killed over 630,000 people and infected over 15,000,000 worldwi...
sars-cov-2;acute kidney injury;dialysis;pandemic;renal transplantation
Journal Article;Review
Gagliardi, Ida;Patella, Gemma;Michael, Ashour;Serra, Raffaele;Provenzano, Michele;Andreucci, Michele
10.3390/jcm9082506
[ 1, 1, 1, 1, 0, 0, 0 ]
[Title]: COVID-19 and the Kidney: From Epidemiology to Clinical Practice. [Abstract]: The new respiratory infectious disease coronavirus disease 2019 (COVID-19) that originated in Wuhan, China, in December 2019 and caused by a new strain of zoonotic coronavirus, named severe acute respiratory syndrome-coronavirus-2 (SA...
32,580,895
Trends Pharmacol Sci
Targeting JAK-STAT Signaling to Control Cytokine Release Syndrome in COVID-19.
Recent advances in the pathophysiologic understanding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has indicated that patients with severe coronavirus disease 2019 (COVID-19) might experience cytokine release syndrome (CRS), characterized by increased interleukin (IL)-6, IL-2, IL-7, IL-...
covid-19;jak inhibitors;cytokine release syndrome
Journal Article;Research Support, Non-U.S. Gov't;Review
Luo, Wei;Li, Yi-Xin;Jiang, Li-Jun;Chen, Qian;Wang, Tao;Ye, Da-Wei
10.1016/j.tips.2020.06.007
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Targeting JAK-STAT Signaling to Control Cytokine Release Syndrome in COVID-19. [Abstract]: Recent advances in the pathophysiologic understanding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has indicated that patients with severe coronavirus disease 2019 (COVID-19) might experi...
32,884,938
Biomed Res Int
Characteristics and Unexpected COVID-19 Diagnoses in Resuscitation Room Patients during the COVID-19 Outbreak-A Retrospective Case Series.
Introduction: Emergency department (ED) triage regarding infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is challenging. During the coronavirus disease 2019 (COVID-19) outbreak in Germany, the diagnostic outcomes of critically ill patients admitted to the resuscitation room in the ED of our ...
Case Reports;Journal Article
Bergrath, Sebastian;Aretz, Olaf;Haake, Hendrik;Ringelstein, Adrian;Greiffendorf, Ingo;Graeven, Ullrich;Windfuhr, Jochen
10.1155/2020/2721381
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Characteristics and Unexpected COVID-19 Diagnoses in Resuscitation Room Patients during the COVID-19 Outbreak-A Retrospective Case Series. [Abstract]: Introduction: Emergency department (ED) triage regarding infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is challenging. During the ...
32,738,137
J Infect Dis
Prospective Study Comparing Deep Throat Saliva With Other Respiratory Tract Specimens in the Diagnosis of Novel Coronavirus Disease 2019.
BACKGROUND: Self-collected specimens have been advocated to avoid infectious exposure to healthcare workers. Self-induced sputum in those with a productive cough and saliva in those without a productive cough have been proposed, but sensitivity remains uncertain. METHODS: We performed a prospective study in 2 regional ...
covid-19;sars-cov-2;coronavirus;diagnosis;saliva
Journal Article;Research Support, Non-U.S. Gov't
Lai, Christopher K C;Chen, Zigui;Lui, Grace;Ling, Lowell;Li, Timothy;Wong, Martin C S;Ng, Rita W Y;Tso, Eugene Y K;Ho, Tracy;Fung, Kitty S C;Ng, Siu T;Wong, Barry K C;Boon, Siaw S;Hui, David S C;Chan, Paul K S
10.1093/infdis/jiaa487
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Prospective Study Comparing Deep Throat Saliva With Other Respiratory Tract Specimens in the Diagnosis of Novel Coronavirus Disease 2019. [Abstract]: BACKGROUND: Self-collected specimens have been advocated to avoid infectious exposure to healthcare workers. Self-induced sputum in those with a productive cough...
33,075,527
Int J Infect Dis
Characteristics of COVID-19 epidemic and control measures to curb transmission in Malaysia.
The first wave of COVID-19 epidemic began in late January in Malaysia and ended with a very small final size. The second wave of infections broke out in late February and grew rapidly in the first 3 weeks. Authorities in the country responded quickly with a series of control strategies collectively known as the Movemen...
covid-19;coronavirus;prevention and control;reproduction number;transmission
Journal Article
Ng, Chris Fook Sheng;Seposo, Xerxes T;Moi, Meng Ling;Tajudin, Muhammad Abdul Basit Ahmad;Madaniyazi, Lina;Sahani, Mazrura
10.1016/j.ijid.2020.10.027
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Characteristics of COVID-19 epidemic and control measures to curb transmission in Malaysia. [Abstract]: The first wave of COVID-19 epidemic began in late January in Malaysia and ended with a very small final size. The second wave of infections broke out in late February and grew rapidly in the first 3 weeks. A...
33,041,110
Am J Emerg Med
Cancer is associated with coronavirus disease (COVID-19) severity and mortality: A pooled analysis.
BACKGROUND: Coronavirus disease 2019 (COVID-19) is a rapidly escalating pandemic that has spread to many parts of the world. As such, there is urgent need to identify predictors of clinical severity in COVID-19 patients. This may be useful for early identification of patients who may require life-saving interventions. ...
covid-19;cancer;mortality;severity
Journal Article
Cheruiyot, Isaac;Kipkorir, Vincent;Ngure, Brian;Misiani, Musa;Munguti, Jeremiah
10.1016/j.ajem.2020.08.025
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Cancer is associated with coronavirus disease (COVID-19) severity and mortality: A pooled analysis. [Abstract]: BACKGROUND: Coronavirus disease 2019 (COVID-19) is a rapidly escalating pandemic that has spread to many parts of the world. As such, there is urgent need to identify predictors of clinical severity ...
32,288,417
J Shanghai Jiaotong Univ Sci
Preliminary Assessment of the COVID-19 Outbreak Using 3-Staged Model e-ISHR.
The outbreak of coronavirus disease 2019 (COVID-19) in Wuhan has aroused widespread concern and attention from all over the world. Many articles have predicted the development of the epidemic. Most of them only use very basic SEIR model without considering the real situation. In this paper, we build a model called e-IS...
coronavirus disease 2019 (covid-19);epidemic prediction, 3-staged model;government's control;hospital system
Journal Article
Li, Sijia;Song, Kun;Yang, Boran;Gao, Yucen;Gao, Xiaofeng
10.1007/s12204-020-2169-0
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Preliminary Assessment of the COVID-19 Outbreak Using 3-Staged Model e-ISHR. [Abstract]: The outbreak of coronavirus disease 2019 (COVID-19) in Wuhan has aroused widespread concern and attention from all over the world. Many articles have predicted the development of the epidemic. Most of them only use very ba...
32,638,344
Aging Clin Exp Res
Comparison of clinical and microbiological diagnoses for older adults with COVID-19 in Wuhan: a retrospective study.
BACKGROUND: The potential differences between a clinical diagnosis of coronavirus disease 2019 (COVID-19) (i.e., symptoms without positive virus test) and a microbiological diagnosis (i.e., positive virus test results) of COVID-19 are not known. AIMS: This study explored the differences between the two types of COVID-1...
covid-19;clinical diagnosis;microbiological diagnosis;older patients;sars-cov-2
Journal Article
Sun, Haiying;Ning, Ruoqi;Tao, Yu;Yu, Chong;Deng, Xiaoyan;Zhao, Caili;Meng, Silu;Xu, Dong;Tang, Fangxu
10.1007/s40520-020-01647-4
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Comparison of clinical and microbiological diagnoses for older adults with COVID-19 in Wuhan: a retrospective study. [Abstract]: BACKGROUND: The potential differences between a clinical diagnosis of coronavirus disease 2019 (COVID-19) (i.e., symptoms without positive virus test) and a microbiological diagnosis...
32,619,549
Cell Syst
Ultra-High-Throughput Clinical Proteomics Reveals Classifiers of COVID-19 Infection.
The COVID-19 pandemic is an unprecedented global challenge, and point-of-care diagnostic classifiers are urgently required. Here, we present a platform for ultra-high-throughput serum and plasma proteomics that builds on ISO13485 standardization to facilitate simple implementation in regulated clinical laboratories. Ou...
covid-19 infection;swath-ms;antiviral immune response;clinical classifiers;high-throughput proteomics;mass spectrometry
Journal Article;Research Support, Non-U.S. Gov't
Messner, Christoph B;Demichev, Vadim;Wendisch, Daniel;Michalick, Laura;White, Matthew;Freiwald, Anja;Textoris-Taube, Kathrin;Vernardis, Spyros I;Egger, Anna-Sophia;Kreidl, Marco;Ludwig, Daniela;Kilian, Christiane;Agostini, Federica;Zelezniak, Aleksej;Thibeault, Charlotte;Pfeiffer, Moritz;Hippenstiel, Stefan;Hocke, Andr...
10.1016/j.cels.2020.05.012
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Ultra-High-Throughput Clinical Proteomics Reveals Classifiers of COVID-19 Infection. [Abstract]: The COVID-19 pandemic is an unprecedented global challenge, and point-of-care diagnostic classifiers are urgently required. Here, we present a platform for ultra-high-throughput serum and plasma proteomics that bui...
32,692,365
JAMA Intern Med
Seroprevalence of Antibodies to SARS-CoV-2 in 10 Sites in the United States, March 23-May 12, 2020.
Importance: Reported cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection likely underestimate the prevalence of infection in affected communities. Large-scale seroprevalence studies provide better estimates of the proportion of the population previously infected. Objective: To estimate preva...
Journal Article
Havers, Fiona P;Reed, Carrie;Lim, Travis;Montgomery, Joel M;Klena, John D;Hall, Aron J;Fry, Alicia M;Cannon, Deborah L;Chiang, Cheng-Feng;Gibbons, Aridth;Krapiunaya, Inna;Morales-Betoulle, Maria;Roguski, Katherine;Rasheed, Mohammad Ata Ur;Freeman, Brandi;Lester, Sandra;Mills, Lisa;Carroll, Darin S;Owen, S Michele;Johns...
10.1001/jamainternmed.2020.4130
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Seroprevalence of Antibodies to SARS-CoV-2 in 10 Sites in the United States, March 23-May 12, 2020. [Abstract]: Importance: Reported cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection likely underestimate the prevalence of infection in affected communities. Large-scale seroprevalen...
32,466,735
Stroke
Clinical Characteristics and Outcomes of COVID-19 Patients With a History of Stroke in Wuhan, China.
BACKGROUND AND PURPOSE: Information on stroke survivors infected with coronavirus disease 2019 (COVID-19) is limited. The aim of this study was to describe specific clinical characteristics and outcomes of patients with COVID-19 with a history of stroke. METHODS: All the confirmed cases of COVID-19 at Tongji Hospital f...
covid-19;cardiovascular disease;comorbidity;platelet count;troponin i
Journal Article;Research Support, Non-U.S. Gov't
Qin, Chuan;Zhou, Luoqi;Hu, Ziwei;Yang, Sheng;Zhang, Shuoqi;Chen, Man;Yu, Haihan;Tian, Dai-Shi;Wang, Wei
10.1161/STROKEAHA.120.030365
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical Characteristics and Outcomes of COVID-19 Patients With a History of Stroke in Wuhan, China. [Abstract]: BACKGROUND AND PURPOSE: Information on stroke survivors infected with coronavirus disease 2019 (COVID-19) is limited. The aim of this study was to describe specific clinical characteristics and outc...
32,851,919
J Biomol Struct Dyn
Targeting COVID-19 (SARS-CoV-2) main protease through active phytochemicals of ayurvedic medicinal plants - Withania somnifera (Ashwagandha), Tinospora cordifolia (Giloy) and Ocimum sanctum (Tulsi) - a molecular docking study.
COVID-19 (Coronavirus disease 2019) is a transmissible disease initiated and propagated through a new virus strain SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) since 31(st) December 2019 in Wuhan city of China and the infection has outspread globally influencing millions of people. Here, an attempt was ...
admet;covid-19 (sars-cov-2) mpro;md simulation;ayurveda;drug-likeness;medicinal plants;molecular docking
Journal Article
Shree, Priya;Mishra, Priyanka;Selvaraj, Chandrabose;Singh, Sanjeev Kumar;Chaube, Radha;Garg, Neha;Tripathi, Yamini Bhusan
10.1080/07391102.2020.1810778
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Targeting COVID-19 (SARS-CoV-2) main protease through active phytochemicals of ayurvedic medicinal plants - Withania somnifera (Ashwagandha), Tinospora cordifolia (Giloy) and Ocimum sanctum (Tulsi) - a molecular docking study. [Abstract]: COVID-19 (Coronavirus disease 2019) is a transmissible disease initiated...
32,879,731
Biomark Res
A meta-analysis of potential biomarkers associated with severity of coronavirus disease 2019 (COVID-19).
Background: Prognostic factors for the Coronavirus disease 2019 (COVID1-9) are not well established. This study aimed to summarize the available data on the association between the severity of COVID-19 and common hematological, inflammatory and biochemical parameters. Methods: EMBASE, MEDLINE, Web of sciences were sear...
covid-19;meta-analysis;prognostic biomarkers
Journal Article;Review
Danwang, Celestin;Endomba, Francky Teddy;Nkeck, Jan Rene;Wouna, Dominic Leandry Angong;Robert, Annie;Noubiap, Jean Jacques
10.1186/s40364-020-00217-0
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: A meta-analysis of potential biomarkers associated with severity of coronavirus disease 2019 (COVID-19). [Abstract]: Background: Prognostic factors for the Coronavirus disease 2019 (COVID1-9) are not well established. This study aimed to summarize the available data on the association between the severity of C...
32,835,285
JACC Case Rep
4 Cases of Aortic Thrombosis in Patients With COVID-19.
Since the outbreak of the COVID-19 pandemic, increasing evidence suggests that infected patients present a high incidence of thrombotic complications. This report describes 4 cases of aortic thrombosis in patients admitted for COVID-19 infection between March 26 and April 12, 2020, in Mulhouse, France. (Level of Diffic...
covid-19;covid-19, coronavirus-2019;ct, computed tomography;rt-pcr, reverse-transcriptase polymerase chain reaction;sars-cov-2;sars-cov-2, severe acute respiratory syndrome-coronavirus-2;aorta;aortic thrombosis
Case Reports
Woehl, Bastien;Lawson, Bree;Jambert, Lucas;Tousch, Jonathan;Ghassani, Afif;Hamade, Amer
10.1016/j.jaccas.2020.06.003
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: 4 Cases of Aortic Thrombosis in Patients With COVID-19. [Abstract]: Since the outbreak of the COVID-19 pandemic, increasing evidence suggests that infected patients present a high incidence of thrombotic complications. This report describes 4 cases of aortic thrombosis in patients admitted for COVID-19 infecti...
32,860,069
Intensive Care Med
Lung ultrasound predicts clinical course and outcomes in COVID-19 patients.
PURPOSE: Information regarding the use of lung ultrasound (LUS) in patients with Coronavirus disease 2019 (COVID-19) is quickly accumulating, but its use for risk stratification and outcome prediction has yet to be described. We performed the first systematic and comprehensive LUS evaluation of consecutive patients hos...
acute respiratory distress syndrome;covid-19;clinical outcomes;lung ultrasound;risk stratification
Journal Article
Lichter, Yael;Topilsky, Yan;Taieb, Philippe;Banai, Ariel;Hochstadt, Aviram;Merdler, Ilan;Gal Oz, Amir;Vine, Jacob;Goren, Or;Cohen, Barak;Sapir, Orly;Granot, Yoav;Mann, Tomer;Friedman, Shirley;Angel, Yoel;Adi, Nimrod;Laufer-Perl, Michal;Ingbir, Merav;Arbel, Yaron;Matot, Idit;Szekely, Yishay
10.1007/s00134-020-06212-1
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Lung ultrasound predicts clinical course and outcomes in COVID-19 patients. [Abstract]: PURPOSE: Information regarding the use of lung ultrasound (LUS) in patients with Coronavirus disease 2019 (COVID-19) is quickly accumulating, but its use for risk stratification and outcome prediction has yet to be describe...
32,871,931
Medicine (Baltimore)
Efficacy and safety of traditional Chinese medicine combined with routine western medicine for the asymptomatic novel coronavirus disease (COVID-19): A Bayesian network meta-analysis protocol.
BACKGROUND: The number of patients infected with novel coronavirus disease (COVID-19) has exceeded 10 million in 2020, and a large proportion of them are asymptomatic. At present, there is still no effective treatment for this disease. Traditional Chinese medicine (TCM) shows a good therapeutic effect on COVID-19, espe...
Journal Article
Wang, Jiahao;Zhu, Xue;Sun, Yuying;Zhang, Xingcai;Zhang, Wei
10.1097/MD.0000000000021927
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Efficacy and safety of traditional Chinese medicine combined with routine western medicine for the asymptomatic novel coronavirus disease (COVID-19): A Bayesian network meta-analysis protocol. [Abstract]: BACKGROUND: The number of patients infected with novel coronavirus disease (COVID-19) has exceeded 10 mill...
33,050,947
Trials
An adaptive randomised placebo controlled phase II trial of antivirals for COVID-19 infection (VIRCO): A structured summary of a study protocol for a randomised controlled trial.
OBJECTIVES: Primary objective: To determine the efficacy of a candidate antiviral on time to virological cure compared to standard of care within 14 days of randomisation Secondary objectives: * To determine the safety of the antiviral * To determine the clinical benefit of the antiviral over placebo according to the W...
covid-19;randomised controlled trial;adaptive;community;favipiravir;protocol;treatment
Clinical Trial, Phase II;Letter;Multicenter Study;Randomized Controlled Trial
McMahon, James H;Lau, Jillian S Y;Roney, Janine;Rogers, Benjamin A;Trubiano, Jason;Sasadeusz, Joseph;Molton, James S;Gardiner, Bradley;Lee, Sue J;Hoy, Jennifer F;Cheng, Allen;Peleg, Anton Y
10.1186/s13063-020-04766-5
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: An adaptive randomised placebo controlled phase II trial of antivirals for COVID-19 infection (VIRCO): A structured summary of a study protocol for a randomised controlled trial. [Abstract]: OBJECTIVES: Primary objective: To determine the efficacy of a candidate antiviral on time to virological cure compared t...
32,704,513
Open Forum Infect Dis
The Clinical and Radiological Manifestations in Coronavirus Disease 2019 With Negative Nucleic Acid Results.
Background: Coronavirus disease 2019 (COVID-19) was a new emerging disease with high infectiousness. Its diagnosis primarily depended on real-time polymerase chain reaction (RT-PCR) results. This study investigated epidemiological, clinical, and radiological characteristics of COVID-19 with negative RT-PCR results befo...
covid-19;rt-pcr;sars-cov-2;chest ct;early diagnosis
Journal Article
Lang, Guanjing;Su, Junwei;Wu, Wenrui;Zhao, Hong;Ying, Shihong;Lou, Haiyan;Shen, Xiaomin;Yin, Michael T;Xu, Kaijin;Liu, Jun;Ren, Cheng;Sheng, Jifang
10.1093/ofid/ofaa252
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: The Clinical and Radiological Manifestations in Coronavirus Disease 2019 With Negative Nucleic Acid Results. [Abstract]: Background: Coronavirus disease 2019 (COVID-19) was a new emerging disease with high infectiousness. Its diagnosis primarily depended on real-time polymerase chain reaction (RT-PCR) results....
32,848,231
Nat Hum Behav
Population-scale longitudinal mapping of COVID-19 symptoms, behaviour and testing.
Despite the widespread implementation of public health measures, coronavirus disease 2019 (COVID-19) continues to spread in the United States. To facilitate an agile response to the pandemic, we developed How We Feel, a web and mobile application that collects longitudinal self-reported survey responses on health, beha...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Allen, William E;Altae-Tran, Han;Briggs, James;Jin, Xin;McGee, Glen;Shi, Andy;Raghavan, Rumya;Kamariza, Mireille;Nova, Nicole;Pereta, Albert;Danford, Chris;Kamel, Amine;Gothe, Patrik;Milam, Evrhet;Aurambault, Jean;Primke, Thorben;Li, Weijie;Inkenbrandt, Josh;Huynh, Tuan;Chen, Evan;Lee, Christina;Croatto, Michael;Bentle...
10.1038/s41562-020-00944-2
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Population-scale longitudinal mapping of COVID-19 symptoms, behaviour and testing. [Abstract]: Despite the widespread implementation of public health measures, coronavirus disease 2019 (COVID-19) continues to spread in the United States. To facilitate an agile response to the pandemic, we developed How We Feel...
33,004,064
Int J Equity Health
Using implementation science to mitigate worsening health inequities in the United States during the COVID-19 pandemic.
With the threat of coronavirus disease 2019 (Covid-19) enduring in the United States, effectively and equitably implementing testing, tracing, and self-isolation as key prevention and detection strategies remain critical to safely re-opening communities. As testing and tracing capacities increase, frameworks are needed...
contact tracing;covid-19;health inequities;implementation outcomes;implementation science;social distancing policies;testing
Letter
Jacobson, Tyler A;Smith, Lauren E;Hirschhorn, Lisa R;Huffman, Mark D
10.1186/s12939-020-01293-2
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Using implementation science to mitigate worsening health inequities in the United States during the COVID-19 pandemic. [Abstract]: With the threat of coronavirus disease 2019 (Covid-19) enduring in the United States, effectively and equitably implementing testing, tracing, and self-isolation as key prevention...
32,551,464
J Biol Regul Homeost Agents
Dexamethasone for COVID-19? Not so fast.
Recent announcements indicated, without sharing any distinct published set of results, that the corticosteroid dexamethasone may reduce mortality of severe COVID-19 patients only. The recent Coronavirus [severe acute respiratory syndrome (SARS)-CoV-2]-associated multiorgan disease, called COVID-19, has high morbidity a...
covid-19;dexamethasone;sars-cov-2;nebulized triamcinolone;pro-inflammatory cytokines
Editorial
Theoharides, T C;Conti, P
10.23812/20-EDITORIAL_1-5
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Dexamethasone for COVID-19? Not so fast. [Abstract]: Recent announcements indicated, without sharing any distinct published set of results, that the corticosteroid dexamethasone may reduce mortality of severe COVID-19 patients only. The recent Coronavirus [severe acute respiratory syndrome (SARS)-CoV-2]-associ...
32,450,346
Pharmacol Res
Biochemical indicators of coronavirus disease 2019 exacerbation and the clinical implications.
Coronavirus Disease 2019 (COVID-19) has sparked a global pandemic, affecting more than 4 million people worldwide. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause acute lung injury (ALI) and even acute respiratory distress syndrome (ARDS); with a fatality of 7.0 %. Accumulating evidence sugge...
coronavirus;cytokine storm;immune escape;inflammation;sars-cov-2
Journal Article;Review
An, Peng-Jiao;Zhu, Yi Zhun;Yang, Li-Ping
10.1016/j.phrs.2020.104946
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Biochemical indicators of coronavirus disease 2019 exacerbation and the clinical implications. [Abstract]: Coronavirus Disease 2019 (COVID-19) has sparked a global pandemic, affecting more than 4 million people worldwide. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause acute lung inj...
33,034,039
J Am Geriatr Soc
Partnering with Local Hospitals and Public Health to Manage COVID-19 Outbreaks in Nursing Homes.
BACKGROUND/OBJECTIVES: Almost half of deaths related to COVID-19 in the United States are linked to nursing homes (NHs). We describe among short-term and long-term residents at three NHs in Michigan the outbreak identification process, universal testing, point prevalence of COVID-19, and subsequent containment efforts,...
covid-19;sars-cov-2;nursing home;outbreak;pandemic
Journal Article;Research Support, N.I.H., Extramural
Montoya, Ana;Jenq, Grace;Mills, John P;Beal, Jennifer;Diviney Chun, Erin;Newton, Duane;Gibson, Kristen;Mantey, Julia;Hurst, Kristen;Jones, Karen;Mody, Lona
10.1111/jgs.16869
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Partnering with Local Hospitals and Public Health to Manage COVID-19 Outbreaks in Nursing Homes. [Abstract]: BACKGROUND/OBJECTIVES: Almost half of deaths related to COVID-19 in the United States are linked to nursing homes (NHs). We describe among short-term and long-term residents at three NHs in Michigan the...
32,792,249
J Infect Chemother
Serial serum SARS-CoV-2 RNA results in two COVID-19 cases with severe respiratory failure.
Coronavirus disease 2019 (COVID-19) is spreading worldwide and poses an imminent threat to public health. We encountered 2 cases of COVID-19 with progression resulting in severe respiratory failure and improvement without any specific treatment. To examine the course of infection, we performed reverse-transcription (RT...
covid-19;serum sars-cov-2 rna;severe respiratory failure
Case Reports
Kodama, Tatsuya;Kouzaki, Yuji;Kawano, Shuichi;Obinata, Hirofumi;Taniguchi, Hiroaki;Sasaki, Hisashi;Ota, Shinichiro;Kawana, Akihiko;Tamura, Kaku
10.1016/j.jiac.2020.07.003
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Serial serum SARS-CoV-2 RNA results in two COVID-19 cases with severe respiratory failure. [Abstract]: Coronavirus disease 2019 (COVID-19) is spreading worldwide and poses an imminent threat to public health. We encountered 2 cases of COVID-19 with progression resulting in severe respiratory failure and improv...
32,738,497
J AAPOS
Review of maternal COVID-19 infection: considerations for the pediatric ophthalmologist.
With the increasing number of COVID-19 cases in the United States, more data is being reported on transmission, symptomatology, clinical course, and treatment of the virus. Research has focused on the trends and unique characteristics in at-risk populations, including pregnant women. This report summarizes the current ...
Journal Article;Review
DiSciullo, Alison;Mokhtari, Neggin;Fries, Melissa
10.1016/j.jaapos.2020.07.003
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Review of maternal COVID-19 infection: considerations for the pediatric ophthalmologist. [Abstract]: With the increasing number of COVID-19 cases in the United States, more data is being reported on transmission, symptomatology, clinical course, and treatment of the virus. Research has focused on the trends an...
32,842,505
Vaccines (Basel)
The Association between Influenza and Pneumococcal Vaccinations and SARS-Cov-2 Infection: Data from the EPICOVID19 Web-Based Survey.
The present study aims to evaluate whether influenza and pneumococcal vaccinations are associated with positive nasopharyngeal swab (NPS) testing to detect SARS-CoV-2. Data from the Italian cross-sectional web-based survey (EPICOVID19), based on a self-selection sample of individuals aged >/=18, were considered. The pr...
covid-19;sars-cov-2;influenza vaccination;nasopharyngeal swab testing;pneumococcal vaccination;web-based survey
Journal Article
Noale, Marianna;Trevisan, Caterina;Maggi, Stefania;Antonelli Incalzi, Raffaele;Pedone, Claudio;Di Bari, Mauro;Adorni, Fulvio;Jesuthasan, Nithiya;Sojic, Aleksandra;Galli, Massimo;Giacomelli, Andrea;Molinaro, Sabrina;Bianchi, Fabrizio;Mastroianni, Claudio;Prinelli, Federica;Group, On Behalf Of The Epicovid Working
10.3390/vaccines8030471
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: The Association between Influenza and Pneumococcal Vaccinations and SARS-Cov-2 Infection: Data from the EPICOVID19 Web-Based Survey. [Abstract]: The present study aims to evaluate whether influenza and pneumococcal vaccinations are associated with positive nasopharyngeal swab (NPS) testing to detect SARS-CoV-2...
32,839,745
Noncoding RNA Res
miRNA target prediction might explain the reduced transmission of SARS-CoV-2 in Jordan, Middle East.
MicroRNAs (miRNAs) are non-coding RNAs that control many functions within the human cells by controlling protein levels through binding to messenger RNA (mRNA) translation process or mRNA abundance. Many pieces of evidence show that miRNAs affect the viral RNA replication and pathogenesis through direct binding to the ...
jordan;sars-cov-2;transmission;mirna
Journal Article
Haddad, Hazem;Walid Al-Zyoud
10.1016/j.ncrna.2020.08.002
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: miRNA target prediction might explain the reduced transmission of SARS-CoV-2 in Jordan, Middle East. [Abstract]: MicroRNAs (miRNAs) are non-coding RNAs that control many functions within the human cells by controlling protein levels through binding to messenger RNA (mRNA) translation process or mRNA abundance....
32,660,204
Ultrasonography
Lung ultrasonography in pregnant women during the COVID-19 pandemic: an interobserver agreement study among obstetricians.
PURPOSE: This study investigated interobserver agreement in lung ultrasonography (LUS) in pregnant women performed by obstetricians with different levels of expertise, with confirmation by an expert radiologist. METHODS: This prospective study was conducted at a tertiary "Coronavirus Pandemic Hospital" in April 2020. P...
covid-19;interobserver variability;lung ultrasound;pregnancy;sars-cov-2
Journal Article
Yassa, Murat;Mutlu, Memis Ali;Birol, Pinar;Kuzan, Taha Yusuf;Kalafat, Erkan;Usta, Canberk;Yavuz, Emre;Keskin, Ilkhan;Tug, Niyazi
10.14366/usg.20084
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Lung ultrasonography in pregnant women during the COVID-19 pandemic: an interobserver agreement study among obstetricians. [Abstract]: PURPOSE: This study investigated interobserver agreement in lung ultrasonography (LUS) in pregnant women performed by obstetricians with different levels of expertise, with con...
32,391,308
Front Public Health
COVID-19 Trend Estimation in the Elderly Italian Region of Sardinia.
December 2019 saw a novel coronavirus (COVID-19) from China quickly spread globally. Currently, COVID-19, defined as the new pandemic by the World Health Organization (WHO), has reached over 750,000 confirmed cases worldwide. The virus began to spread in Italy from the 22nd February, and the number of related cases is ...
covid-19;sird-model;coronavirus;pandemic;public health emergency
Journal Article
Puci, Mariangela Valentina;Loi, Federica;Ferraro, Ottavia Eleonora;Cappai, Stefano;Rolesu, Sandro;Montomoli, Cristina
10.3389/fpubh.2020.00153
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: COVID-19 Trend Estimation in the Elderly Italian Region of Sardinia. [Abstract]: December 2019 saw a novel coronavirus (COVID-19) from China quickly spread globally. Currently, COVID-19, defined as the new pandemic by the World Health Organization (WHO), has reached over 750,000 confirmed cases worldwide. The ...
32,580,396
Int J Environ Res Public Health
Using Mind-Body Modalities via Telemedicine during the COVID-19 Crisis: Cases in the Republic of Korea.
The coronavirus disease 2019 (COVID-19) pandemic affected the world, and its deleterious effects on human domestic life, society, economics, and especially on human mental health are expected to continue. Mental health experts highlighted health issues this pandemic may cause, such as depression, anxiety, obsessive com...
covid-19;mind-body intervention;new-normal;telemedicine
Journal Article
Kwon, Chan-Young;Kwak, Hui-Yong;Kim, Jong Woo
10.3390/ijerph17124477
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Using Mind-Body Modalities via Telemedicine during the COVID-19 Crisis: Cases in the Republic of Korea. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic affected the world, and its deleterious effects on human domestic life, society, economics, and especially on human mental health are expected to ...
32,735,448
Br J Radiol
Pulmonary thromboembolism in hospitalised COVID-19 patients at moderate to high risk by Wells score: a report from Lombardy, Italy.
OBJECTIVES: To present a single-centre experience on CT pulmonary angiography (CTPA) for the assessment of hospitalised COVID-19 patients with moderate-to-high risk of pulmonary thromboembolism (PTE). METHODS: We analysed consecutive COVID-19 patients (RT-PCR confirmed) undergoing CTPA in March 2020 for PTE clinical su...
Journal Article;Observational Study
Monfardini, Lorenzo;Morassi, Mauro;Botti, Paolo;Stellini, Roberto;Bettari, Luca;Pezzotti, Stefania;Ali, Marco;Monaco, Cristian Giuseppe;Magni, Veronica;Cozzi, Andrea;Schiaffino, Simone;Bna, Claudio
10.1259/bjr.20200407
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Pulmonary thromboembolism in hospitalised COVID-19 patients at moderate to high risk by Wells score: a report from Lombardy, Italy. [Abstract]: OBJECTIVES: To present a single-centre experience on CT pulmonary angiography (CTPA) for the assessment of hospitalised COVID-19 patients with moderate-to-high risk of...
32,692,228
Ann Palliat Med
Clinical outcome of standardized oxygen therapy nursing strategy in COVID-19.
BACKGROUND: Novel coronavirus pneumonia (COVID-19) has become a global pandemic. However, a technical standard for oxygen therapy nursing, as well as how this would improve clinical outcomes and symptoms, is yet to be explored. METHODS: From February 9, 2020, to March 31, 2020, 58 patients of confirmed COVID-19 were ad...
oxygen therapy;novel coronavirus pneumonia (covid-19);nursing
Journal Article
Pan, Wenyan;Li, Jingjing;Ou, Yufeng;Wu, Yitao;Cai, Shining;Zhang, Yuxia;Wang, Chunling
10.21037/apm-20-1272
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Clinical outcome of standardized oxygen therapy nursing strategy in COVID-19. [Abstract]: BACKGROUND: Novel coronavirus pneumonia (COVID-19) has become a global pandemic. However, a technical standard for oxygen therapy nursing, as well as how this would improve clinical outcomes and symptoms, is yet to be exp...
32,351,873
Z Gesundh Wiss
Will the antimalarial drug take over to combat COVID-19?
Background: China has been fighting the epidemic of pneumonia-like diseases first detected for over a month in the city of Wuhan in December 2019. The disease epidemic is caused by a novel coronavirus, called COVID-19, which has now infected more than 700,000 people worldwide. With a death toll approaching that of Chin...
covid-19;china;chloroquine;hydroxychloroquine;outbreak;wuhan
Journal Article;Review
T K, Sivabakya;G, Srinivas
10.1007/s10389-020-01293-0
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Will the antimalarial drug take over to combat COVID-19? [Abstract]: Background: China has been fighting the epidemic of pneumonia-like diseases first detected for over a month in the city of Wuhan in December 2019. The disease epidemic is caused by a novel coronavirus, called COVID-19, which has now infected ...
33,013,423
Front Pharmacol
Age-Dependent Assessment of Genes Involved in Cellular Senescence, Telomere, and Mitochondrial Pathways in Human Lung Tissue of Smokers, COPD, and IPF: Associations With SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 Axis.
Background: Aging is one of the key contributing factors for chronic obstructive pulmonary diseases (COPD) and other chronic inflammatory lung diseases. Here, we determined how aging contributes to the altered gene expression related to mitochondrial function, cellular senescence, and telomeric length processes that pl...
dna damage;aging;cellular senescence;chronic obstructive pulmonary diseases;idiopathic pulmonary fibrosis;mitochondria;smokers;telomere
Journal Article
Maremanda, Krishna P;Sundar, Isaac K;Li, Dongmei;Rahman, Irfan
10.3389/fphar.2020.584637
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Age-Dependent Assessment of Genes Involved in Cellular Senescence, Telomere, and Mitochondrial Pathways in Human Lung Tissue of Smokers, COPD, and IPF: Associations With SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 Axis. [Abstract]: Background: Aging is one of the key contributing factors for chronic obstructiv...
32,768,702
Int J Infect Dis
Cluster infections play important roles in the rapid evolution of COVID-19 transmission: A systematic review.
OBJECTIVES: To summarise the major types of SARS-CoV-2 cluster infections worldwide through a comprehensive systematic review. METHODS: All studies published between 01 January-15 June 2020 on COVID-19 cluster infections in English electronic databases were searched, including PubMed, Embase, Web of Knowledge, and Scop...
covid-19;cluster infection;novel coronavirus;sars-cov-2;systematic review
Journal Article;Systematic Review
Liu, Tao;Gong, Dexin;Xiao, Jianpeng;Hu, Jianxiong;He, Guanhao;Rong, Zuhua;Ma, Wenjun
10.1016/j.ijid.2020.07.073
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Cluster infections play important roles in the rapid evolution of COVID-19 transmission: A systematic review. [Abstract]: OBJECTIVES: To summarise the major types of SARS-CoV-2 cluster infections worldwide through a comprehensive systematic review. METHODS: All studies published between 01 January-15 June 2020...
32,592,550
Cent Eur J Public Health
Can wearing face masks in public affect transmission route and viral load in COVID-19?
The mandatory face mask wearing was implemented in the Czech Republic and Slovakia shortly after the COVID-19 outbreak in Central Europe. So far, the number of COVID-19-associated deaths per 100,000 individuals is far lower in these countries as compared with other neighbouring or close countries. The use of face masks...
covid-19;covid-19 face masks;immunity;transmission route;viral load
Journal Article
Strizova, Zuzana;Bartunkova, Jirina;Smrz, Daniel
10.21101/cejph.a6290
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Can wearing face masks in public affect transmission route and viral load in COVID-19? [Abstract]: The mandatory face mask wearing was implemented in the Czech Republic and Slovakia shortly after the COVID-19 outbreak in Central Europe. So far, the number of COVID-19-associated deaths per 100,000 individuals i...
32,596,244
Front Cell Dev Biol
The Inhibitory Effect of Curcumin on Virus-Induced Cytokine Storm and Its Potential Use in the Associated Severe Pneumonia.
Coronavirus infection, including SARS-CoV, MERS-CoV, and SARS-CoV2, causes daunting diseases that can be fatal because of lung failure and systemic cytokine storm. The development of coronavirus-evoked pneumonia is associated with excessive inflammatory responses in the lung, known as "cytokine storms," which results i...
coronavirus;curcumin;cytokine storm;lung injury;pneumonia
Journal Article;Review
Liu, Ziteng;Ying, Ying
10.3389/fcell.2020.00479
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The Inhibitory Effect of Curcumin on Virus-Induced Cytokine Storm and Its Potential Use in the Associated Severe Pneumonia. [Abstract]: Coronavirus infection, including SARS-CoV, MERS-CoV, and SARS-CoV2, causes daunting diseases that can be fatal because of lung failure and systemic cytokine storm. The develop...
32,855,798
J Surg Case Rep
SARS-CoV-2 isolation from an appendix.
Efforts to recognize SARS-CoV-2 infection have focused on respiratory symptoms such as cough and shortness of breath. Although it is also well known that SARS-CoV-2 infection can cause gastrointestinal symptoms such as abdominal pain, nausea, vomiting and diarrhoea, there are emerging reports of SARS-CoV-2 infection ca...
Case Reports
Ahmad, Shahzaib;Ahmed, Rahim Nadeem;Jani, Poonam;Ullah, Mattee;Aboulgheit, Hossam
10.1093/jscr/rjaa245
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: SARS-CoV-2 isolation from an appendix. [Abstract]: Efforts to recognize SARS-CoV-2 infection have focused on respiratory symptoms such as cough and shortness of breath. Although it is also well known that SARS-CoV-2 infection can cause gastrointestinal symptoms such as abdominal pain, nausea, vomiting and diar...
32,582,617
Front Public Health
Identification of RT-PCR-Negative Asymptomatic COVID-19 Patients via Serological Testing.
Asymptomatic individuals with coronavirus disease (COVID-19) have been identified via nucleic acid testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); however, the epidemiologic characteristics and viral shedding pattern of asymptomatic patients remain largely unknown. In this study, serological t...
covid-19;sars-cov-2;asymptomatic;reverse transcription polymerase chain reaction;serological test
Journal Article;Research Support, Non-U.S. Gov't
Wu, Jinru;Liu, Xinyi;Zhou, Dan;Qiu, Guangqian;Dai, Miao;Yang, Qingting;Pan, Zhonghui;Zhou, Ning;Wu, Pa
10.3389/fpubh.2020.00267
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Identification of RT-PCR-Negative Asymptomatic COVID-19 Patients via Serological Testing. [Abstract]: Asymptomatic individuals with coronavirus disease (COVID-19) have been identified via nucleic acid testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); however, the epidemiologic character...
32,330,313
J Med Virol
Asymptomatic COVID-19 infection in late pregnancy indicated no vertical transmission.
This study is to investigate the clinical characteristics of late pregnancy with asymptomatic 2019 novel coronavirus disease (COVID-19) infection, evaluate the outcome of maternal and fetal prognosis, and identify the evidence of intrauterine vertical transmission. A 22-years-old pregnant woman with asymptomatic COVID-...
asymptomatic covid-19 infection;intrauterine infection;late pregnancy;vertical transmission
Case Reports;Journal Article;Research Support, Non-U.S. Gov't
Lu, Dawei;Sang, Lin;Du, Shihua;Li, Tao;Chang, Yange;Yang, Xiu-An
10.1002/jmv.25927
[ 0, 0, 0, 0, 1, 0, 0 ]
[Title]: Asymptomatic COVID-19 infection in late pregnancy indicated no vertical transmission. [Abstract]: This study is to investigate the clinical characteristics of late pregnancy with asymptomatic 2019 novel coronavirus disease (COVID-19) infection, evaluate the outcome of maternal and fetal prognosis, and identify...
32,389,859
Pharmacol Res
Brief recommendations on the management of adult patients with familial hypercholesterolemia during the COVID-19 pandemic.
Individuals with Familial Hypercholesterolaemia (FH) are at very high risk of cardiovascular disease, which is associated with poor outcomes from coronavirus infections. COVID-19 puts strain on healthcare systems and may impair access to routine FH services. On behalf of the International Lipid Expert Panel (ILEP) and ...
cholesterol;coronavirus;covid-19;prevention;risk stratification;statins;therapy
Journal Article
Banach, Maciej;Penson, Peter E;Fras, Zlatko;Vrablik, Michal;Pella, Daniel;Reiner, Zeljko;Nabavi, Seyed Mohammad;Sahebkar, Amirhossein;Kayikcioglu, Meral;Daccord, Magdalena
10.1016/j.phrs.2020.104891
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Brief recommendations on the management of adult patients with familial hypercholesterolemia during the COVID-19 pandemic. [Abstract]: Individuals with Familial Hypercholesterolaemia (FH) are at very high risk of cardiovascular disease, which is associated with poor outcomes from coronavirus infections. COVID-...
32,529,906
Emerg Microbes Infect
Serological differentiation between COVID-19 and SARS infections.
In response to the coronavirus disease 2019 (COVID-19) outbreak, caused by SARS-CoV-2, multiple diagnostic tests are required for acute disease diagnosis, contact tracing, monitoring asymptomatic infection rates and assessing herd immunity. While PCR remains the frontline test of choice in the acute diagnostic setting,...
covid-19;sars;sars-cov-2;antibody;serology
Clinical Trial;Comparative Study;Journal Article
Chia, Wan Ni;Tan, Chee Wah;Foo, Randy;Kang, Adrian Eng Zheng;Peng, Yilong;Sivalingam, Velraj;Tiu, Charles;Ong, Xin Mei;Zhu, Feng;Young, Barnaby E;Chen, Mark I-C;Tan, Yee-Joo;Lye, David C;Anderson, Danielle E;Wang, Lin-Fa
10.1080/22221751.2020.1780951
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Serological differentiation between COVID-19 and SARS infections. [Abstract]: In response to the coronavirus disease 2019 (COVID-19) outbreak, caused by SARS-CoV-2, multiple diagnostic tests are required for acute disease diagnosis, contact tracing, monitoring asymptomatic infection rates and assessing herd im...
32,794,025
Cerebellum
Consensus on Virtual Management of Vestibular Disorders: Urgent Versus Expedited Care.
The virtual practice has made major advances in the way that we care for patients in the modern era. The culture of virtual practice, consulting, and telemedicine, which had started several years ago, took an accelerated leap as humankind was challenged by the novel coronavirus pandemic (COVID19). The social distancing...
brainstem;cerebellum;emergency room;stroke;vestibular neuritis
Journal Article;Practice Guideline;Review
Shaikh, Aasef G;Bronstein, Adolfo;Carmona, Sergio;Cha, Yoon-Hee;Cho, Catherine;Ghasia, Fatema F;Gold, Daniel;Green, Kemar E;Helmchen, Christoph;Ibitoye, Richard T;Kattah, Jorge;Kim, Ji-Soo;Kothari, Sudhir;Manto, Mario;Seemungal, Barry M;Straumann, Dominik;Strupp, Michael;Szmulewicz, David;Tarnutzer, Alexander;Tehrani, ...
10.1007/s12311-020-01178-8
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Consensus on Virtual Management of Vestibular Disorders: Urgent Versus Expedited Care. [Abstract]: The virtual practice has made major advances in the way that we care for patients in the modern era. The culture of virtual practice, consulting, and telemedicine, which had started several years ago, took an acc...
32,574,236
Front Pharmacol
Available Evidence and Ongoing Clinical Trials of Remdesivir: Could It Be a Promising Therapeutic Option for COVID-19?
The novel coronavirus strain, severe acute respiratory syndrome coronavirus-2, the causative agent of COVID-19 emerged in Wuhan, China, in December 2019 and is skyrocketing throughout the globe and become a global public health emergency. Despite promising preventive measures being taken, there is no vaccine or drug th...
covid-19;gs-5734;rdrp;sars-cov-2;remdesivir
Journal Article;Review
Sisay, Mekonnen
10.3389/fphar.2020.00791
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Available Evidence and Ongoing Clinical Trials of Remdesivir: Could It Be a Promising Therapeutic Option for COVID-19? [Abstract]: The novel coronavirus strain, severe acute respiratory syndrome coronavirus-2, the causative agent of COVID-19 emerged in Wuhan, China, in December 2019 and is skyrocketing through...
32,897,296
JAMA Neurol
Assessment of Brain Injury Using Portable, Low-Field Magnetic Resonance Imaging at the Bedside of Critically Ill Patients.
Importance: Neuroimaging is a key step in the clinical evaluation of brain injury. Conventional magnetic resonance imaging (MRI) systems operate at high-strength magnetic fields (1.5-3 T) that require strict, access-controlled environments. Limited access to timely neuroimaging remains a key structural barrier to effec...
Journal Article
Sheth, Kevin N;Mazurek, Mercy H;Yuen, Matthew M;Cahn, Bradley A;Shah, Jill T;Ward, Adrienne;Kim, Jennifer A;Gilmore, Emily J;Falcone, Guido J;Petersen, Nils;Gobeske, Kevin T;Kaddouh, Firas;Hwang, David Y;Schindler, Joseph;Sansing, Lauren;Matouk, Charles;Rothberg, Jonathan;Sze, Gordon;Siner, Jonathan;Rosen, Matthew S;Sp...
10.1001/jamaneurol.2020.3263
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Assessment of Brain Injury Using Portable, Low-Field Magnetic Resonance Imaging at the Bedside of Critically Ill Patients. [Abstract]: Importance: Neuroimaging is a key step in the clinical evaluation of brain injury. Conventional magnetic resonance imaging (MRI) systems operate at high-strength magnetic field...