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32,634,603
Int J Antimicrob Agents
COVID-19 treatment: close to a cure? A rapid review of pharmacotherapies for the novel coronavirus (SARS-CoV-2).
Currently, there is no approved therapy for coronavirus disease 2019 (COVID-19). The World Health Organization (WHO) therefore endorses supportive care only. However, frontline clinicians and researchers have been experimenting with several virus-based and host-based therapeutics since the outbreak of severe acute resp...
covid-19;china's covid-19 guide;hydroxychloroquine;il-6 inhibitor;remdesivir;xuebijing
Journal Article;Review
Song, Yang;Zhang, Min;Yin, Ling;Wang, Kunkun;Zhou, Yiyi;Zhou, Mi;Lu, Yun
10.1016/j.ijantimicag.2020.106080
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 treatment: close to a cure? A rapid review of pharmacotherapies for the novel coronavirus (SARS-CoV-2). [Abstract]: Currently, there is no approved therapy for coronavirus disease 2019 (COVID-19). The World Health Organization (WHO) therefore endorses supportive care only. However, frontline clinician...
32,339,508
Ann Thorac Surg
Novel Percutaneous Tracheostomy for Critically Ill Patients With COVID-19.
BACKGROUND: Coronavirus 2019 (COVID-19) is a worldwide pandemic, with many patients requiring prolonged mechanical ventilation. Tracheostomy is not recommended by current guidelines as it is considered a superspreading event owing to aerosolization that unduly risks health care workers. METHODS: Patients with severe CO...
Journal Article
Angel, Luis;Kon, Zachary N;Chang, Stephanie H;Rafeq, Samaan;Palasamudram Shekar, Saketh;Mitzman, Brian;Amoroso, Nancy;Goldenberg, Ronald;Sureau, Kimberly;Smith, Deane E;Cerfolio, Robert J
10.1016/j.athoracsur.2020.04.010
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Novel Percutaneous Tracheostomy for Critically Ill Patients With COVID-19. [Abstract]: BACKGROUND: Coronavirus 2019 (COVID-19) is a worldwide pandemic, with many patients requiring prolonged mechanical ventilation. Tracheostomy is not recommended by current guidelines as it is considered a superspreading event...
32,551,814
Arch Pathol Lab Med
Coagulation Dysfunction.
CONTEXT.-: The coronavirus disease 2019 (COVID-19) is a highly contagious respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coagulation dysfunction is a hallmark in patients with COVID-19. Fulminant thrombotic complications emerge as critical issues in patients with severe COVI...
Journal Article;Systematic Review
Fei, Yang;Tang, Ning;Liu, Hefei;Cao, Wenjing
10.5858/arpa.2020-0324-SA
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Coagulation Dysfunction. [Abstract]: CONTEXT.-: The coronavirus disease 2019 (COVID-19) is a highly contagious respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coagulation dysfunction is a hallmark in patients with COVID-19. Fulminant thrombotic complications emerge a...
32,949,985
Clin Neurophysiol
Continuous electroencephalography characteristics and acute symptomatic seizures in COVID-19 patients.
OBJECTIVE: As concerns regarding neurological manifestations in COVID-19 (coronavirus disease 2019) patients increase, limited data exists on continuous electroencephalography (cEEG) findings in these patients. We present a retrospective cohort study of cEEG monitoring in COVID-19 patients to better explore this knowle...
covid-19;critical illness;electroencephalography (eeg);seizures
Journal Article;Research Support, N.I.H., Extramural
Louis, Shreya;Dhawan, Andrew;Newey, Christopher;Nair, Dileep;Jehi, Lara;Hantus, Stephen;Punia, Vineet
10.1016/j.clinph.2020.08.003
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Continuous electroencephalography characteristics and acute symptomatic seizures in COVID-19 patients. [Abstract]: OBJECTIVE: As concerns regarding neurological manifestations in COVID-19 (coronavirus disease 2019) patients increase, limited data exists on continuous electroencephalography (cEEG) findings in t...
32,530,282
J Chem Inf Model
Computational Determination of Potential Inhibitors of SARS-CoV-2 Main Protease.
The novel coronavirus (SARS-CoV-2) has infected several million people and caused thousands of deaths worldwide since December 2019. As the disease is spreading rapidly all over the world, it is urgent to find effective drugs to treat the virus. The main protease (Mpro) of SARS-CoV-2 is one of the potential drug target...
Journal Article
Ngo, Son Tung;Quynh Anh Pham, Ngoc;Thi Le, Ly;Pham, Duc-Hung;Vu, Van V
10.1021/acs.jcim.0c00491
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Computational Determination of Potential Inhibitors of SARS-CoV-2 Main Protease. [Abstract]: The novel coronavirus (SARS-CoV-2) has infected several million people and caused thousands of deaths worldwide since December 2019. As the disease is spreading rapidly all over the world, it is urgent to find effectiv...
32,837,554
Asian Bioeth Rev
Rationing in a Pandemic: Lessons from Italy.
In late February and early March 2020, Italy became the European epicenter of the COVID-19 pandemic. Despite increasingly stringent containment measures enforced by the government, the health system faced an enormous pressure, and extraordinary efforts were made in order to increase overall hospital beds' availability ...
allocation;covid-19;italy;rationing;resources
Journal Article
Craxi, Lucia;Vergano, Marco;Savulescu, Julian;Wilkinson, Dominic
10.1007/s41649-020-00127-1
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Rationing in a Pandemic: Lessons from Italy. [Abstract]: In late February and early March 2020, Italy became the European epicenter of the COVID-19 pandemic. Despite increasingly stringent containment measures enforced by the government, the health system faced an enormous pressure, and extraordinary efforts w...
32,805,684
J Clin Anesth
Caseload is increased by resequencing cases before and on the day of surgery at ambulatory surgery centers where initial patient recovery is in operating rooms and cleanup times are longer than typical.
STUDY OBJECTIVE: The coronavirus disease 2019 (COVID-19) pandemic impacts operating room (OR) management in regions with high prevalence (e.g., >1.0% of asymptomatic patients testing positive). Cases with aerosol producing procedures are isolated to a few ORs, initial phase I recovery of those patients is in the ORs, a...
Journal Article
Wang, Zhengli;Dexter, Franklin;Zenios, Stefanos A
10.1016/j.jclinane.2020.110024
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Caseload is increased by resequencing cases before and on the day of surgery at ambulatory surgery centers where initial patient recovery is in operating rooms and cleanup times are longer than typical. [Abstract]: STUDY OBJECTIVE: The coronavirus disease 2019 (COVID-19) pandemic impacts operating room (OR) ma...
32,755,822
Diabetes Metab Syndr
Applications of industry 4.0 to overcome the COVID-19 operational challenges.
BACKGROUND AND AIMS: An epidemic outbreak of COVID-19 has increased the demand for medical equipment, medical accessories along with daily essentials for the safety of healthcare workers. This study aims to identify the operational challenges faced by retailers in providing efficient services. The study also aimed to p...
covid-19;coronavirus;epidemic outbreak;industry-4.0;retail industry;supply chain
Journal Article
Kumar, Mr Shashank;Raut, Dr Rakesh D;Narwane, Dr Vaibhav S;Narkhede, Dr Balkrishna E
10.1016/j.dsx.2020.07.010
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Applications of industry 4.0 to overcome the COVID-19 operational challenges. [Abstract]: BACKGROUND AND AIMS: An epidemic outbreak of COVID-19 has increased the demand for medical equipment, medical accessories along with daily essentials for the safety of healthcare workers. This study aims to identify the o...
32,347,054
Sheng Wu Gong Cheng Xue Bao
[Strategies for vaccine development of COVID-19].
An epidemic of acute respiratory syndrome in humans, which appeared in Wuhan, China in December 2019, was caused by a novel coronavirus (SARS-CoV-2). This disease was named as "Coronavirus Disease 2019" (COVID-19). SARS-CoV-2 was first identified as an etiological pathogen of COVID-19, belonging to the species of sever...
covid-19;antibody;antibody-dependent enhancement;mucosal immunization;vaccine
Journal Article;Review
Yang, Limin;Tian, Deyu;Liu, Wenjun
10.13345/j.cjb.200094
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: [Strategies for vaccine development of COVID-19]. [Abstract]: An epidemic of acute respiratory syndrome in humans, which appeared in Wuhan, China in December 2019, was caused by a novel coronavirus (SARS-CoV-2). This disease was named as "Coronavirus Disease 2019" (COVID-19). SARS-CoV-2 was first identified as...
32,638,107
J Neurol
Impact of COVID-19 on U.S. and Canadian neurologists' therapeutic approach to multiple sclerosis: a survey of knowledge, attitudes, and practices.
OBJECTIVE: To report the understanding and decision-making of neuroimmunologists and their treatment of patients with multiple sclerosis (MS) during the early stages of the SARS-CoV-2 (COVID-19) outbreak. METHODS: A survey instrument was designed and distributed online to neurologists in April 2020. RESULTS: There were...
covid-19;disease-modifying therapy;health behaviors;immunosuppression;multiple sclerosis;neuroimmunology;neurologist
Journal Article
Mateen, Farrah J;Rezaei, Shawheen;Alakel, Nicholas;Gazdag, Brittany;Kumar, Aditya Ravi;Vogel, Andre
10.1007/s00415-020-10045-9
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of COVID-19 on U.S. and Canadian neurologists' therapeutic approach to multiple sclerosis: a survey of knowledge, attitudes, and practices. [Abstract]: OBJECTIVE: To report the understanding and decision-making of neuroimmunologists and their treatment of patients with multiple sclerosis (MS) during the...
32,403,007
J Clin Virol
Self-collection: An appropriate alternative during the SARS-CoV-2 pandemic.
OBJECTIVES: To evaluate the reliability of self-collection for SARS-CoV-2 and other respiratory viruses because swab collections for SARS-CoV-2 put health workers at risk of infection and require use of personal protective equipment (PPE). METHODS: In a prospective study, patients from two states in Australia attending...
covid-19;diagnosis;pcr;respiratory viruses;sars-cov-2;self-collection
Comparative Study;Evaluation Study;Journal Article
Wehrhahn, Michael C;Robson, Jennifer;Brown, Suzanne;Bursle, Evan;Byrne, Shane;New, David;Chong, Smathi;Newcombe, James P;Siversten, Terri;Hadlow, Narelle
10.1016/j.jcv.2020.104417
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Self-collection: An appropriate alternative during the SARS-CoV-2 pandemic. [Abstract]: OBJECTIVES: To evaluate the reliability of self-collection for SARS-CoV-2 and other respiratory viruses because swab collections for SARS-CoV-2 put health workers at risk of infection and require use of personal protective ...
32,705,977
Am J Trop Med Hyg
A University-Wide Preparedness Effort in the Alert Phase of COVID-19 Incorporating Community Mental Health and Task-Shifting Strategies: Experience from a Bornean Institute of Higher Learning.
The COVID-19 pandemic caught the world by surprise, causing millions of confirmed cases and hundreds of thousands of deaths. Hence, the Malaysian government announced a Movement Control Order at the start of the containment phase to flatten the epidemiological curve. Universiti Malaysia Sabah (UMS), a public university...
Journal Article
Mukhsam, Mohamad Hafiz;Jeffree, Mohammad Saffree;Pang, Nicholas Tze Ping;Syed Abdul Rahim, Syed Sharizman;Omar, Azizan;Abdullah, Muhammad Syafiq;Lukman, Khamisah Awang;Giloi, Nelbon;Salvaraji, Loganathan;Abd Karim, Mohd Rahimie;Saupin, Sahipudin;Boon Tat, Yeap;Mohd Hayati, Mohd Firdaus;Ibrahim, Mohd Yusof;Muhamad, Assi...
10.4269/ajtmh.20-0458
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A University-Wide Preparedness Effort in the Alert Phase of COVID-19 Incorporating Community Mental Health and Task-Shifting Strategies: Experience from a Bornean Institute of Higher Learning. [Abstract]: The COVID-19 pandemic caught the world by surprise, causing millions of confirmed cases and hundreds of th...
32,893,759
Bosn J Basic Med Sci
The value of lymphocyte count in determining the severity of COVID-19 and estimating the time for nucleic acid test results to turn negative.
Peripheral blood lymphocyte count is shown to be decreased in patients with COVID-19 in the early stage of the disease. The degree of lymphocyte count reduction is related to COVID-19 severity and could be used as an indicator to reflect the disease severity. Our aim was to investigate the value of lymphocyte count in ...
Journal Article
Li, Yuanchao;Yang, Tuoyun;Wang, Sicong;Zheng, Junbo;Zhou, Jing;Jiang, Min;Zhou, Tong;Cao, Yang;Wang, Hongliang
10.17305/bjbms.2020.4868
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: The value of lymphocyte count in determining the severity of COVID-19 and estimating the time for nucleic acid test results to turn negative. [Abstract]: Peripheral blood lymphocyte count is shown to be decreased in patients with COVID-19 in the early stage of the disease. The degree of lymphocyte count reduct...
32,659,214
Lancet Haematol
Haematological characteristics and risk factors in the classification and prognosis evaluation of COVID-19: a retrospective cohort study.
BACKGROUND: COVID-19 is an ongoing global pandemic. Changes in haematological characteristics in patients with COVID-19 are emerging as important features of the disease. We aimed to explore the haematological characteristics and related risk factors in patients with COVID-19. METHODS: This retrospective cohort study i...
Journal Article
Liao, Danying;Zhou, Fen;Luo, Lili;Xu, Min;Wang, Hongbo;Xia, Jiahong;Gao, Yong;Cai, Liqiong;Wang, Zhihui;Yin, Ping;Wang, Yadan;Tang, Lu;Deng, Jun;Mei, Heng;Hu, Yu
10.1016/S2352-3026(20)30217-9
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Haematological characteristics and risk factors in the classification and prognosis evaluation of COVID-19: a retrospective cohort study. [Abstract]: BACKGROUND: COVID-19 is an ongoing global pandemic. Changes in haematological characteristics in patients with COVID-19 are emerging as important features of the...
32,374,544
Rev Med Suisse
[Venous thrombotic risk related to SARS-CoV-2 : prevalence, recommendations and perspectives].
Since the SARS-CoV-2 pandemic outbreak, growing evidence suggests that patients suffering from COVID-19 are at increased risk of thrombotic events. The sepsis-related activation of the coagulation combined with a high prevalence of common thrombotic risk factors could contribute to this prothrombotic state. Coagulation...
Journal Article;Review
Casini, Alessandro;Fontana, Pierre;Glauser, Frederic;Robert-Ebadi, Helia;Righini, Marc;Blondon, Marc
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: [Venous thrombotic risk related to SARS-CoV-2 : prevalence, recommendations and perspectives]. [Abstract]: Since the SARS-CoV-2 pandemic outbreak, growing evidence suggests that patients suffering from COVID-19 are at increased risk of thrombotic events. The sepsis-related activation of the coagulation combine...
32,843,531
J Clin Microbiol
Can We Test Our Way Out of the COVID-19 Pandemic?
Frequent, low-cost, universal testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with quarantine of those with a positive result has been suggested as a strategy to address the coronavirus disease 2019 (COVID-19) pandemic in the United States. Specifically, home or community use of tests that use ...
covid-19;sars-cov-2
Editorial
Pettengill, Matthew A;McAdam, Alexander J
10.1128/JCM.02225-20
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Can We Test Our Way Out of the COVID-19 Pandemic? [Abstract]: Frequent, low-cost, universal testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with quarantine of those with a positive result has been suggested as a strategy to address the coronavirus disease 2019 (COVID-19) pandemic in th...
32,764,417
Int J Environ Res Public Health
The Global Emergency of Novel Coronavirus (SARS-CoV-2): An Update of the Current Status and Forecasting.
Over the past two decades, there have been two major outbreaks where the crossover of animal Betacoronaviruses to humans has resulted in severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). In December 2019, a global public health concern started with the...
ace2;covid-19;sars-cov-2;diagnosis;epidemiology;inhibitors;pneumonia;temperature and humidity;therapeutics strategies;transmission
Journal Article;Review
Hozhabri, Hossein;Piceci Sparascio, Francesca;Sohrabi, Hamidreza;Mousavifar, Leila;Roy, Rene;Scribano, Daniela;De Luca, Alessandro;Ambrosi, Cecilia;Sarshar, Meysam
10.3390/ijerph17165648
[ 1, 1, 1, 1, 0, 0, 0 ]
[Title]: The Global Emergency of Novel Coronavirus (SARS-CoV-2): An Update of the Current Status and Forecasting. [Abstract]: Over the past two decades, there have been two major outbreaks where the crossover of animal Betacoronaviruses to humans has resulted in severe acute respiratory syndrome coronavirus (SARS-CoV) ...
33,052,821
West J Emerg Med
Underutilization of the Emergency Department During the COVID-19 Pandemic.
INTRODUCTION: The novel coronavirus 2019 (COVID-19) pandemic in the United States (US) prompted widespread containment measures such as shelter-in-place (SIP) orders. The goal of our study was to determine whether there was a significant change in overall volume and proportion of emergency department (ED) encounters si...
Journal Article;Observational Study
Lucero, Anthony D;Lee, Andre;Hyun, Jenny;Lee, Carol;Kahwaji, Chadi;Miller, Gregg;Neeki, Michael;Tamayo-Sarver, Joshua;Pan, Luhong
10.5811/westjem.2020.8.48632
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Underutilization of the Emergency Department During the COVID-19 Pandemic. [Abstract]: INTRODUCTION: The novel coronavirus 2019 (COVID-19) pandemic in the United States (US) prompted widespread containment measures such as shelter-in-place (SIP) orders. The goal of our study was to determine whether there was ...
32,940,880
CEN Case Rep
Efficacy of favipiravir for an end stage renal disease patient on maintenance hemodialysis infected with novel coronavirus disease 2019.
BACKGROUND: Novel coronavirus disease 2019 (COVID-19) refers to infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen, and has spread to pandemic levels since its inception in December 2019. While several risk factors for severe presentation have been identified, the clinical course f...
covid-19;end-stage renal disease;favipiravir;hemodialysis;sars-cov-2
Case Reports;Journal Article
Koshi, Eri;Saito, Shoji;Okazaki, Masaki;Toyama, Yuki;Ishimoto, Takuji;Kosugi, Tomoki;Hiraiwa, Hiroaki;Jingushi, Naruhiro;Yamamoto, Takanori;Ozaki, Masayuki;Goto, Yukari;Numaguchi, Atsushi;Miyagawa, Yasuhiro;Kato, Io;Tetsuka, Nobuyuki;Yagi, Tetsuya;Maruyama, Shoichi
10.1007/s13730-020-00534-1
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Efficacy of favipiravir for an end stage renal disease patient on maintenance hemodialysis infected with novel coronavirus disease 2019. [Abstract]: BACKGROUND: Novel coronavirus disease 2019 (COVID-19) refers to infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen, and has ...
32,281,785
ACS Nano
Dual-Functional Plasmonic Photothermal Biosensors for Highly Accurate Severe Acute Respiratory Syndrome Coronavirus 2 Detection.
The ongoing outbreak of the novel coronavirus disease (COVID-19) has spread globally and poses a threat to public health in more than 200 countries. Reliable laboratory diagnosis of the disease has been one of the foremost priorities for promoting public health interventions. The routinely used reverse transcription po...
lspr;rna virus;biosensors;coronavirus disease;nuclei acids;plasmonic photothermal effect;severe acute respiratory syndrome coronavirus 2
Journal Article
Qiu, Guangyu;Gai, Zhibo;Tao, Yile;Schmitt, Jean;Kullak-Ublick, Gerd A;Wang, Jing
10.1021/acsnano.0c02439
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Dual-Functional Plasmonic Photothermal Biosensors for Highly Accurate Severe Acute Respiratory Syndrome Coronavirus 2 Detection. [Abstract]: The ongoing outbreak of the novel coronavirus disease (COVID-19) has spread globally and poses a threat to public health in more than 200 countries. Reliable laboratory d...
32,485,959
Int J Environ Res Public Health
COVID-19 Outbreak Perception in Italian Dentists.
The aim of this study is an evaluation of the Italian dentists' knowledge regarding COVID-19 and their perception of the risks associated with COVID-19, their attitude in resuming their activities, and how they judge the institutional intervention on a health and economic basis. METHODS: This research evaluated Italian...
covid-19;sars-cov-2;dentistry;infection control;questionnaire
Journal Article
De Stefani, Alberto;Bruno, Giovanni;Mutinelli, Sabrina;Gracco, Antonio
10.3390/ijerph17113867
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 Outbreak Perception in Italian Dentists. [Abstract]: The aim of this study is an evaluation of the Italian dentists' knowledge regarding COVID-19 and their perception of the risks associated with COVID-19, their attitude in resuming their activities, and how they judge the institutional intervention o...
32,458,536
Dermatol Ther
Considerations for safety in the use of systemic medications for psoriasis and atopic dermatitis during the COVID-19 pandemic.
Coronavirus disease 2019 (COVID-19) is responsible for at least 2 546 527 cases and 175 812 deaths as of April 21, 2020. Psoriasis and atopic dermatitis (AD) are common, chronic, inflammatory skin conditions, with immune dysregulation as a shared mechanism; therefore, mainstays of treatment include systemic immunomodul...
covid-19;atopic dermatitis;biologics;immunosuppression;psoriasis
Journal Article;Review
Ricardo, Jose W;Lipner, Shari R
10.1111/dth.13687
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Considerations for safety in the use of systemic medications for psoriasis and atopic dermatitis during the COVID-19 pandemic. [Abstract]: Coronavirus disease 2019 (COVID-19) is responsible for at least 2 546 527 cases and 175 812 deaths as of April 21, 2020. Psoriasis and atopic dermatitis (AD) are common, ch...
33,055,123
BMJ Open
Public perception of COVID-19 management and response in Nigeria: a cross-sectional survey.
OBJECTIVES: A study designed to assess the public perception of the response of government and its institutions to the COVID-19 pandemic in Nigeria. SETTING: Self-selecting participants throughout Nigeria completed a self-administered questionnaire through an online cross-sectional survey. PARTICIPANTS: 495. RESULTS: T...
epidemiology;infection control;organisational development
Journal Article;Multicenter Study;Research Support, Non-U.S. Gov't
Oleribe, Obinna;Ezechi, Oliver;Osita-Oleribe, Princess;Olawepo, Olatayo;Musa, Adesola Z;Omoluabi, Anddy;Fertleman, Michael;Salako, Babatunde L;Taylor-Robinson, Simon D
10.1136/bmjopen-2020-041936
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Public perception of COVID-19 management and response in Nigeria: a cross-sectional survey. [Abstract]: OBJECTIVES: A study designed to assess the public perception of the response of government and its institutions to the COVID-19 pandemic in Nigeria. SETTING: Self-selecting participants throughout Nigeria co...
32,313,822
Virusdisease
Recent apprise on coronavirus and its terrible insinuations.
Epidemically increased evidence reveals that the link between the 2019-nCoV and other similar strain of coronaviruses circulating in bats and specifically the Rhinopodous bat sub-species. These sub-species are ample and widely present in Southern China, Middle East Africa and Europe. Recent studies show that more than ...
coronavirus;hem agglutinin esterase (he);human coronavirus nl63;middle east respiratory syndrome coronavirus (mers-cov);new coronavirus (2019-ncov);rrt-pcr tests
Journal Article
Bhattacharya, Sankha;Sharma, Priyanka;Mathur, Harshita;Rasheed, Haamid;Singh, Saranjit;Rajput, Geeta;Agnihotri, Suyash;Nirmal, Puneet;Kaur, Sukhbir
10.1007/s13337-020-00582-2
[ 1, 1, 1, 1, 1, 0, 0 ]
[Title]: Recent apprise on coronavirus and its terrible insinuations. [Abstract]: Epidemically increased evidence reveals that the link between the 2019-nCoV and other similar strain of coronaviruses circulating in bats and specifically the Rhinopodous bat sub-species. These sub-species are ample and widely present in ...
32,652,520
J Pediatric Infect Dis Soc
Guillain-Barre Syndrome Associated With Severe Acute Respiratory Syndrome Coronavirus 2 Detection and Coronavirus Disease 2019 in a Child.
Coronavirus disease (COVID-19) is caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Physicians in China reported what is believed to be the first adult case of a SARS-CoV-2 infection associated with acute Guillain-Barre syndrome (GBS), followed by 5 adult Italian patients and anothe...
covid-19;guillain-barre syndrome;sars-cov-2;child
Case Reports;Journal Article
Khalifa, Maher;Zakaria, Fairouz;Ragab, Yasser;Saad, Ahmed;Bamaga, Ahmed;Emad, Yasser;Rasker, Johannes J
10.1093/jpids/piaa086
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Guillain-Barre Syndrome Associated With Severe Acute Respiratory Syndrome Coronavirus 2 Detection and Coronavirus Disease 2019 in a Child. [Abstract]: Coronavirus disease (COVID-19) is caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Physicians in China reported what is be...
32,530,033
J Public Health (Oxf)
Descriptive analysis of social determinant factors in urban communities affected by COVID-19.
OBJECTIVES: To provide a descriptive analysis of communities severely impacted by COVID-19 to that of communities moderately affected by COVID-19, with an emphasis on the social determinant factors within them. METHODS: To compare the communities with extremely high COVID-19 rates to that of communities with moderate C...
covid-19;descriptive analysis;health disparities;severely affected communities;social determinants
Comparative Study;Journal Article
Harlem, Gunness;Lynn, Millheiser
10.1093/pubmed/fdaa078
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Descriptive analysis of social determinant factors in urban communities affected by COVID-19. [Abstract]: OBJECTIVES: To provide a descriptive analysis of communities severely impacted by COVID-19 to that of communities moderately affected by COVID-19, with an emphasis on the social determinant factors within ...
32,626,720
Front Med (Lausanne)
Nasopharyngeal Swabs Are More Sensitive Than Oropharyngeal Swabs for COVID-19 Diagnosis and Monitoring the SARS-CoV-2 Load.
Objective: Detection of SARS-CoV-2 by oropharyngeal swabs (OPS) and nasopharyngeal swabs (NPS) is an essential method for coronavirus disease 2019 (COVID-19) management. It is not clear how detection rate, sensitivity, and the risk of exposure for medical providers differ in two sampling methods. Methods: In this prosp...
covid-19;sars-cov-2;nasopharyngeal swab;oropharyngeal swab;sensitivity;viral load
Journal Article
Wang, Huan;Liu, Qian;Hu, Jing;Zhou, Min;Yu, Mu-Qing;Li, Kai-Yan;Xu, Dong;Xiao, Yao;Yang, Jun-Yi;Lu, Yan-Jun;Wang, Feng;Yin, Ping;Xu, Shu-Yun
10.3389/fmed.2020.00334
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Nasopharyngeal Swabs Are More Sensitive Than Oropharyngeal Swabs for COVID-19 Diagnosis and Monitoring the SARS-CoV-2 Load. [Abstract]: Objective: Detection of SARS-CoV-2 by oropharyngeal swabs (OPS) and nasopharyngeal swabs (NPS) is an essential method for coronavirus disease 2019 (COVID-19) management. It is...
32,959,892
J Cell Physiol
Quantitative proteomics reveals a broad-spectrum antiviral property of ivermectin, benefiting for COVID-19 treatment.
Viruses such as human cytomegalovirus (HCMV), human papillomavirus (HPV), Epstein-Barr virus (EBV), human immunodeficiency virus (HIV), and coronavirus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) represent a great burden to human health worldwide. FDA-approved anti-parasite drug ivermectin is also an...
sars-cov-2/covid-19;ivermectin;quantitative proteomics;stable isotope labeling by amino acids in cell culture;virus-related pathways
Journal Article;Research Support, Non-U.S. Gov't
Li, Na;Zhao, Lingfeng;Zhan, Xianquan
10.1002/jcp.30055
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Quantitative proteomics reveals a broad-spectrum antiviral property of ivermectin, benefiting for COVID-19 treatment. [Abstract]: Viruses such as human cytomegalovirus (HCMV), human papillomavirus (HPV), Epstein-Barr virus (EBV), human immunodeficiency virus (HIV), and coronavirus (severe acute respiratory syn...
32,557,214
BioDrugs
Potential Role of Anti-interleukin (IL)-6 Drugs in the Treatment of COVID-19: Rationale, Clinical Evidence and Risks.
The epidemic due to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection has been spreading globally, raising increasing concerns. This public health emergency has triggered a race to find medications to improve the prognosis of this disease. There is currently great interest in drug repositioning to ...
Journal Article;Review
Crisafulli, Salvatore;Isgro, Valentina;La Corte, Laura;Atzeni, Fabiola;Trifiro, Gianluca
10.1007/s40259-020-00430-1
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Potential Role of Anti-interleukin (IL)-6 Drugs in the Treatment of COVID-19: Rationale, Clinical Evidence and Risks. [Abstract]: The epidemic due to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection has been spreading globally, raising increasing concerns. This public health emergency has...
32,546,655
Neurology
Neurochemical evidence of astrocytic and neuronal injury commonly found in COVID-19.
OBJECTIVE: To test the hypothesis that coronavirus disease 2019 (COVID-19) has an impact on the CNS by measuring plasma biomarkers of CNS injury. METHODS: We recruited 47 patients with mild (n = 20), moderate (n = 9), or severe (n = 18) COVID-19 and measured 2 plasma biomarkers of CNS injury by single molecule array, n...
Journal Article;Research Support, Non-U.S. Gov't
Kanberg, Nelly;Ashton, Nicholas J;Andersson, Lars-Magnus;Yilmaz, Aylin;Lindh, Magnus;Nilsson, Staffan;Price, Richard W;Blennow, Kaj;Zetterberg, Henrik;Gisslen, Magnus
10.1212/WNL.0000000000010111
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Neurochemical evidence of astrocytic and neuronal injury commonly found in COVID-19. [Abstract]: OBJECTIVE: To test the hypothesis that coronavirus disease 2019 (COVID-19) has an impact on the CNS by measuring plasma biomarkers of CNS injury. METHODS: We recruited 47 patients with mild (n = 20), moderate (n = ...
32,358,232
ASAIO J
Advanced Pulmonary and Cardiac Support of COVID-19 Patients: Emerging Recommendations From ASAIO-A "Living Working Document".
The severe acute respiratory syndrome (SARS)-CoV-2 is an emerging viral pathogen responsible for the global coronavirus disease 2019 (COVID)-19 pandemic resulting in significant human morbidity and mortality. Based on preliminary clinical reports, hypoxic respiratory failure complicated by acute respiratory distress sy...
Journal Article;Review
Rajagopal, Keshava;Keller, Steven P;Akkanti, Bindu;Bime, Christian;Loyalka, Pranav;Cheema, Faisal H;Zwischenberger, Joseph B;El Banayosy, Aly;Pappalardo, Federico;Slaughter, Mark S;Slepian, Marvin J
10.1097/MAT.0000000000001180
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Advanced Pulmonary and Cardiac Support of COVID-19 Patients: Emerging Recommendations From ASAIO-A "Living Working Document". [Abstract]: The severe acute respiratory syndrome (SARS)-CoV-2 is an emerging viral pathogen responsible for the global coronavirus disease 2019 (COVID)-19 pandemic resulting in signifi...
32,984,209
Front Pediatr
The Recommendations for the Management of Chinese Children With Epilepsy During the COVID-19 Outbreak.
The coronavirus disease (COVID-19) is the most severe public health problem facing the world currently. Social distancing and avoidance of unnecessary movements are preventive strategies that are being advocated to prevent the spread of the causative virus [severe acute respiratory syndrome (SARS)-CoV2]. It is known th...
covid-19;sars-cov2;children;epilepsy;management recommendations
Journal Article
Chen, Baiyu;Kessi, Miriam;Chen, Shimeng;Xiong, Juan;Wu, Liwen;Deng, Xiaolu;Yang, Lifen;He, Fang;Yin, Fei;Peng, Jing
10.3389/fped.2020.00495
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Recommendations for the Management of Chinese Children With Epilepsy During the COVID-19 Outbreak. [Abstract]: The coronavirus disease (COVID-19) is the most severe public health problem facing the world currently. Social distancing and avoidance of unnecessary movements are preventive strategies that are ...
32,458,150
J Exp Orthop
The role of the orthopaedic surgeon in the COVID-19 era: cautions and perspectives.
The current coronavirus disease 2019 (COVID-19) pandemic has revolutionized global healthcare in an unprecedented way and with unimaginable repercussions. Resource reallocation, socioeconomic confinement and reorganization of production activities are current challenges being faced both at the national and internationa...
covid-19;coronavirus;education;elective surgery;orthopaedic surgery;ppe;sars-cov-2;surgical algorithm;surgical indication;telemedicine
Journal Article;Review
Ambrosio, Luca;Vadala, Gianluca;Russo, Fabrizio;Papalia, Rocco;Denaro, Vincenzo
10.1186/s40634-020-00255-5
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The role of the orthopaedic surgeon in the COVID-19 era: cautions and perspectives. [Abstract]: The current coronavirus disease 2019 (COVID-19) pandemic has revolutionized global healthcare in an unprecedented way and with unimaginable repercussions. Resource reallocation, socioeconomic confinement and reorgan...
32,445,583
Pediatr Dermatol
Erythema multiforme-like lesions in children and COVID-19.
During examination of cases of chilblains in children and adolescents, we identified four patients who also showed skin lesions similar to erythema multiforme (EM). They had no other known triggers for EM. One of them had a positive PCR for SARS-CoV-2, while the other three were negative. Skin biopsies from two patient...
covid-19;sars-cov-2;chilblains;erythema multiforme;exanthem;pernio;skin;viral diseases
Case Reports;Journal Article
Torrelo, Antonio;Andina, David;Santonja, Carlos;Noguera-Morel, Lucero;Bascuas-Arribas, Marta;Gaitero-Tristan, Jara;Alonso-Cadenas, Jose Antonio;Escalada-Pellitero, Silvia;Hernandez-Martin, Angela;de la Torre-Espi, Mercedes;Colmenero, Isabel
10.1111/pde.14246
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Erythema multiforme-like lesions in children and COVID-19. [Abstract]: During examination of cases of chilblains in children and adolescents, we identified four patients who also showed skin lesions similar to erythema multiforme (EM). They had no other known triggers for EM. One of them had a positive PCR for...
33,039,790
Mar Pollut Bull
Using Copernicus Sentinel-2 and Sentinel-3 data to monitor harmful algal blooms in Southern Chile during the COVID-19 lockdown.
During the southern summer of 2020, large phytoplankton blooms were detected using satellite technology in Chile (western Patagonia), where intensive salmonid aquaculture is carried out. Some harvesting sites recorded massive fish mortalities, which were associated with the presence of the dinoflagellate species Cochlo...
covid-19 lockdown;copernicus programme;dinoflagellates;harmful algal blooms;remote sensing;salmonid aquaculture
Journal Article
Rodriguez-Benito, Cristina V;Navarro, Gabriel;Caballero, Isabel
10.1016/j.marpolbul.2020.111722
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Using Copernicus Sentinel-2 and Sentinel-3 data to monitor harmful algal blooms in Southern Chile during the COVID-19 lockdown. [Abstract]: During the southern summer of 2020, large phytoplankton blooms were detected using satellite technology in Chile (western Patagonia), where intensive salmonid aquaculture ...
32,282,614
J Neurosurg Anesthesiol
Anesthetic Management of Endovascular Treatment of Acute Ischemic Stroke During COVID-19 Pandemic: Consensus Statement From Society for Neuroscience in Anesthesiology & Critical Care (SNACC): Endorsed by Society of Vascular & Interventional Neurology (SVIN), Society of NeuroInterventional Surgery (SNIS), Neurocritical ...
The pandemic of coronavirus disease 2019 (COVID-19) has unique implications for the anesthetic management of endovascular therapy for acute ischemic stroke. The Society for Neuroscience in Anesthesiology and Critical Care appointed a task force to provide timely, consensus-based expert recommendations using available e...
Journal Article;Practice Guideline
Sharma, Deepak;Rasmussen, Mads;Han, Ruquan;Whalin, Matthew K;Davis, Melinda;Kofke, W Andrew;Venkatraghvan, Lakshmikumar;Raychev, Radoslav;Fraser, Justin F
10.1097/ANA.0000000000000688
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Anesthetic Management of Endovascular Treatment of Acute Ischemic Stroke During COVID-19 Pandemic: Consensus Statement From Society for Neuroscience in Anesthesiology & Critical Care (SNACC): Endorsed by Society of Vascular & Interventional Neurology (SVIN), Society of NeuroInterventional Surgery (SNIS), Neuro...
32,933,641
Zhongguo Dang Dai Er Ke Za Zhi
[Possibility of mother-to-child vertical transmission of coronavirus infection from the perspectives of severe acute respiratory syndrome, Middle East respiratory syndrome, and coronavirus disease 2019].
This article evaluates the potential influence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pregnant women on the development of coronavirus disease 2019 in neonates and discusses the possibility of mother-to-child vertical transmission of SARS-CoV-2. With reference to related articles p...
Journal Article
Luo, Fang;DU, Li-Zhong
[ 0, 0, 0, 0, 1, 0, 0 ]
[Title]: [Possibility of mother-to-child vertical transmission of coronavirus infection from the perspectives of severe acute respiratory syndrome, Middle East respiratory syndrome, and coronavirus disease 2019]. [Abstract]: This article evaluates the potential influence of severe acute respiratory syndrome coronavirus...
32,932,347
Crit Care Med
Probative Value of the D-Dimer Assay for Diagnosis of Deep Venous Thrombosis in the Coronavirus Disease 2019 Syndrome.
OBJECTIVES: To describe the predictive utility of the D-dimer assay among patients with the coronavirus disease 2019 syndrome for unprovoked lower extremity deep venous thrombosis. DESIGN: Prospective observational study with retrospective data analysis. SETTING: Academic medical center surgical ICU. PATIENTS: Seventy-...
Journal Article;Observational Study
Gibson, Cameron J;Alqunaibit, Dalia;Smith, Kira E;Bronstein, Matthew;Eachempati, Soumitra R;Kelly, Anton G;Lee, Christina;Minneman, Jennifer A;Narayan, Mayur;Shou, Jian;Villegas, Cassandra V;Winchell, Robert J;Barie, Philip S
10.1097/CCM.0000000000004614
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Probative Value of the D-Dimer Assay for Diagnosis of Deep Venous Thrombosis in the Coronavirus Disease 2019 Syndrome. [Abstract]: OBJECTIVES: To describe the predictive utility of the D-dimer assay among patients with the coronavirus disease 2019 syndrome for unprovoked lower extremity deep venous thrombosis....
32,909,961
Aging (Albany NY)
Clinical course and risk factors for recurrence of positive SARS-CoV-2 RNA: a retrospective cohort study from Wuhan, China.
The coronavirus disease 2019 (COVID-19) pandemic is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The objective of this study was to determine the clinical course and risk factors for patients showing recurrent SARS-CoV-2 RNA positivity. A total of 1087 COVID-19 patients confirmed by RT-PC...
covid-19;sars-cov-2;clinical course;coronavirus disease 2019;recurrence;risk factor
Journal Article
Chen, Jie;Xu, Xiaoping;Hu, Jing;Chen, Qiangda;Xu, Fengfeng;Liang, Hui;Liu, Nanmei;Zhu, Hengmei;Lan, Jinlong;Zhou, Lan;Xing, Jiajun;Pu, Ning;Cai, Zhigang
10.18632/aging.103795
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Clinical course and risk factors for recurrence of positive SARS-CoV-2 RNA: a retrospective cohort study from Wuhan, China. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The objective of this study was to determine th...
32,205,186
Autoimmun Rev
COVID-19 infection and rheumatoid arthritis: Faraway, so close!
The outbreak of the new coronavirus infections COVID-19 in December 2019 in China has quickly become a global health emergency. Given the lack of specific anti-viral therapies, the current management of severe acute respiratory syndrome coronaviruses (SARS-CoV-2) is mainly supportive, even though several compounds are ...
covid-19;coronavirus;cytokine release syndrome;dmards;rheumatoid arthritis;treatment
Journal Article;Review
Favalli, Ennio Giulio;Ingegnoli, Francesca;De Lucia, Orazio;Cincinelli, Gilberto;Cimaz, Rolando;Caporali, Roberto
10.1016/j.autrev.2020.102523
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 infection and rheumatoid arthritis: Faraway, so close! [Abstract]: The outbreak of the new coronavirus infections COVID-19 in December 2019 in China has quickly become a global health emergency. Given the lack of specific anti-viral therapies, the current management of severe acute respiratory syndrom...
33,047,040
R Soc Open Sci
Super-spreading events initiated the exponential growth phase of COVID-19 with 0 higher than initially estimated.
The basic reproduction number R 0 of the coronavirus disease 2019 has been estimated to range between 2 and 4. Here, we used an SEIR model that properly accounts for the distribution of the latent period and, based on empirical estimates of the doubling time in the near-exponential phases of epidemic progression in Chi...
covid-19;reproduction number
Journal Article
Kochanczyk, Marek;Grabowski, Frederic;Lipniacki, Tomasz
10.1098/rsos.200786
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Super-spreading events initiated the exponential growth phase of COVID-19 with 0 higher than initially estimated. [Abstract]: The basic reproduction number R 0 of the coronavirus disease 2019 has been estimated to range between 2 and 4. Here, we used an SEIR model that properly accounts for the distribution of...
32,855,827
Case Rep Cardiol
ST Elevations in the Era of COVID-19.
Myocardial injury, represented by elevated cardiac enzymes, has been associated with increased morbidity and mortality in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections. Coronavirus disease 2019 (COVID-19) has created unique challenges in approaching patients with acute ST-segment changes. We d...
Case Reports
Sang, Charlie Joseph 3rd;Heindl, Brittain;Von Mering, Gregory;Brott, Brigitta;Kopf, Robert S;Rajapreyar, Indranee
10.1155/2020/8845627
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: ST Elevations in the Era of COVID-19. [Abstract]: Myocardial injury, represented by elevated cardiac enzymes, has been associated with increased morbidity and mortality in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections. Coronavirus disease 2019 (COVID-19) has created unique challenges ...
32,988,441
J Prim Health Care
Wearing one for the team: views and attitudes to face covering in New Zealand/Aotearoa during COVID-19 Alert Level 4 lockdown.
INTRODUCTION Mass masking is emerging as a key non-pharmaceutical intervention for reducing community spread of COVID-19. However, although hand washing, social distancing and bubble living have been widely adopted by the 'team of 5 million', mass masking has not been socialised to the general population. AIM To identi...
Journal Article;Research Support, Non-U.S. Gov't
Gray, Lesley;MacDonald, Carol;Tassell-Matamua, Natasha;Stanley, James;Kvalsvig, Amanda;Zhang, Jane;Murton, Samantha;Wiles, Siouxsie;Puloka, Viliami;Becker, Julia;Johnston, David;Baker, Michael G
10.1071/HC20089
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Wearing one for the team: views and attitudes to face covering in New Zealand/Aotearoa during COVID-19 Alert Level 4 lockdown. [Abstract]: INTRODUCTION Mass masking is emerging as a key non-pharmaceutical intervention for reducing community spread of COVID-19. However, although hand washing, social distancing ...
32,329,432
Am J Trop Med Hyg
COVID-19 Serosurveillance May Facilitate Return-to-Work Decisions.
Public health measures are needed to resolve the novel coronavirus disease (COVID-19) pandemic, although a looming economic fallout merits close attention. Early safe reintroduction of immune individuals into the workforce may be essential to protecting the economic welfare of communities. Reverse transcriptase-polymer...
Journal Article
Krsak, Martin;Johnson, Steven C;Poeschla, Eric M
10.4269/ajtmh.20-0302
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 Serosurveillance May Facilitate Return-to-Work Decisions. [Abstract]: Public health measures are needed to resolve the novel coronavirus disease (COVID-19) pandemic, although a looming economic fallout merits close attention. Early safe reintroduction of immune individuals into the workforce may be es...
32,915,959
J Crohns Colitis
Intestinal receptor of SARS-CoV-2 in inflamed IBD tissue seems downregulated by HNF4A in ileum and upregulated by interferon regulating factors in colon.
BACKGROUND: Patients with IBD are considered immunosuppressed, but do not seem more vulnerable for COVID-19. Nevertheless, intestinal inflammation has shown an important risk factor for SARS-CoV-2 infection and prognosis. Therefore, we investigated the role of intestinal inflammation on the viral intestinal entry mecha...
ace2;covid-19;hnf4a;sars-cov-2;tmprss2;inflammatory bowel diseases;interferon;intestinal inflammation;organoids;single cell;transcriptomics
Journal Article
Verstockt, Bram;Verstockt, Sare;Abdu Rahiman, Saeed;Ke, Bo-Jun;Arnauts, Kaline;Cleynen, Isabelle;Sabino, Joao;Ferrante, Marc;Matteoli, Gianluca;Vermeire, Severine
10.1093/ecco-jcc/jjaa185
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Intestinal receptor of SARS-CoV-2 in inflamed IBD tissue seems downregulated by HNF4A in ileum and upregulated by interferon regulating factors in colon. [Abstract]: BACKGROUND: Patients with IBD are considered immunosuppressed, but do not seem more vulnerable for COVID-19. Nevertheless, intestinal inflammatio...
32,493,833
BMJ Evid Based Med
COVID-19 and the US response: accelerating health inequities.
Health inequities have long defined health and the healthcare system in the USA. The clinical and research capacity across the USA is unparalleled, yet compared to other high and even some middle-income countries, the average health indicators of the population remain suboptimal in 2020, a finding at least in part expl...
delivery of healthcare;healthcare quality, access, and evaluation;infectious disease medicine;public health;socioeconomic factors
Journal Article
Okonkwo, Nneoma E;Aguwa, Ugochi T;Jang, Minyoung;Barre, Iman A;Page, Kathleen R;Sullivan, Patrick S;Beyrer, Chris;Baral, Stefan
10.1136/bmjebm-2020-111426
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 and the US response: accelerating health inequities. [Abstract]: Health inequities have long defined health and the healthcare system in the USA. The clinical and research capacity across the USA is unparalleled, yet compared to other high and even some middle-income countries, the average health indi...
32,794,466
J Infect Dev Ctries
Clinical, Radiological Features and Outcome of COVID-19 patients in a Secondary Hospital in Jakarta, Indonesia.
INTRODUCTION: The numbers of people infected with SARS-CoV-2 in Indonesia especially in Jakarta as the epicenter continue to rise. Limited published clinical data, scarcity and long turn over time of diagnostic testing put clinician in dilemma to make diagnosis. METHODOLOGY: This is an observational case series study f...
covid-19;diagnosis;limited resources
Journal Article;Observational Study
Hafiz, Muhammad;Icksan, Aziza Ghanie;Harlivasari, Annisa Dian;Aulia, Rizky;Susanti, Febrina;Eldinia, Lourisa
10.3855/jidc.12911
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical, Radiological Features and Outcome of COVID-19 patients in a Secondary Hospital in Jakarta, Indonesia. [Abstract]: INTRODUCTION: The numbers of people infected with SARS-CoV-2 in Indonesia especially in Jakarta as the epicenter continue to rise. Limited published clinical data, scarcity and long turn ...
32,876,273
Cien Saude Colet
Interfaces and "Silver Bullets": Technologies and Policies.
This paper discusses the understanding of complex health events, such as the pandemics involving SARS-CoV-2. It supports that simplifying the issue to the point of considering it just a consequence of contact between a pathogen and a susceptible human being overly weakens the effectiveness of the mitigation strategies....
Journal Article
Guimaraes, Reinaldo
10.1590/1413-81232020259.22292020
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Interfaces and "Silver Bullets": Technologies and Policies. [Abstract]: This paper discusses the understanding of complex health events, such as the pandemics involving SARS-CoV-2. It supports that simplifying the issue to the point of considering it just a consequence of contact between a pathogen and a susce...
33,069,829
Genomics
Clustering and classification of virus sequence through music communication protocol and wavelet transform.
The coronavirus pandemic became a major risk in global public health. The outbreak is caused by SARS-CoV-2, a member of the coronavirus family. Though the images of the virus are familiar to us, in the present study, an attempt is made to hear the coronavirus by translating its protein spike into audio sequences. The m...
coronavirus;haar wavelet;midi;protein music;svm
Journal Article;Research Support, Non-U.S. Gov't
Paul, Tirthankar;Vainio, Seppo;Roning, Juha
10.1016/j.ygeno.2020.10.009
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Clustering and classification of virus sequence through music communication protocol and wavelet transform. [Abstract]: The coronavirus pandemic became a major risk in global public health. The outbreak is caused by SARS-CoV-2, a member of the coronavirus family. Though the images of the virus are familiar to ...
32,427,403
Head Neck
Safe and effective management of tracheostomy in COVID-19 patients.
BACKGROUND: An increasing number of COVID-19 patients worldwide will probably need tracheostomy in an emergency or at the recovering stage of COVID-19. We explored the safe and effective management of tracheostomy in COVID-19 patients, to benefit patients and protect health care workers at the same time. METHODS: We re...
covid-19;nosocomial infection;open;percutaneous;tracheostomy
Journal Article;Observational Study
Zhang, Xiaomeng;Huang, Qiling;Niu, Xun;Zhou, Tao;Xie, Zhen;Zhong, Yi;Xiao, Hongjun
10.1002/hed.26261
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Safe and effective management of tracheostomy in COVID-19 patients. [Abstract]: BACKGROUND: An increasing number of COVID-19 patients worldwide will probably need tracheostomy in an emergency or at the recovering stage of COVID-19. We explored the safe and effective management of tracheostomy in COVID-19 patie...
32,388,470
J Clin Virol
Rapid and sensitive detection of SARS-CoV-2 RNA using the Simplexa COVID-19 direct assay.
BACKGROUND: So far, one of the major drawbacks of the available molecular assays for the diagnosis of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) is the need for viral nucleic acid extraction from clinical specimens. OBJECTIVE: The aim of this study was to evaluate the performances of a newly designed ...
rapid response;real-time rt-pcr;sars-cov-2;surveillance
Journal Article;Research Support, Non-U.S. Gov't
Bordi, Licia;Piralla, Antonio;Lalle, Eleonora;Giardina, Federica;Colavita, Francesca;Tallarita, Monica;Sberna, Giuseppe;Novazzi, Federica;Meschi, Silvia;Castilletti, Concetta;Brisci, Angela;Minnucci, Giulia;Tettamanzi, Veronica;Baldanti, Fausto;Capobianchi, Maria Rosaria
10.1016/j.jcv.2020.104416
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Rapid and sensitive detection of SARS-CoV-2 RNA using the Simplexa COVID-19 direct assay. [Abstract]: BACKGROUND: So far, one of the major drawbacks of the available molecular assays for the diagnosis of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) is the need for viral nucleic acid extraction ...
33,005,276
Can Respir J
Clinical Characteristics of Asymptomatic Patients with SARS-CoV-2 in Zhejiang: An Imperceptible Source of Infection.
Objective: Coronavirus disease 2019 (COVID-19), caused by the novel coronavirus SARS-CoV-2, was first identified in December 2019 in Wuhan, China, and has since spread globally, resulting in an ongoing pandemic. However, the study of asymptomatic patients is still rare, and the understanding of its potential transmissi...
Journal Article;Research Support, Non-U.S. Gov't
Dai, Wei;Chen, Xinmiao;Xu, Xiaoting;Leng, Zhefeng;Yu, Wenwen;Lin, Hui;Li, Huiying;Lin, Jie;Qiu, Zhangwei;Dai, Yuanrong
10.1155/2020/2045341
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical Characteristics of Asymptomatic Patients with SARS-CoV-2 in Zhejiang: An Imperceptible Source of Infection. [Abstract]: Objective: Coronavirus disease 2019 (COVID-19), caused by the novel coronavirus SARS-CoV-2, was first identified in December 2019 in Wuhan, China, and has since spread globally, resu...
32,546,459
Indian J Med Ethics
The Covid-19 pandemic and India's cardiovascular disease burden: Finding the right balance.
The national lockdown in India has (thus far) prevented a surge of Covid-19 cases. Due to crowded living conditions and poor social security, infectious spread may be difficult to contain and mitigate. India's healthcare system must respond to impending Covid-19 cases, as well as chronic, non-communicable diseases. Acu...
Journal Article
Chalasani, Meghana;Nasir, Khurram;Gupta, Mohit D;Kalra, Ankur
10.20529/IJME.2020.059
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Covid-19 pandemic and India's cardiovascular disease burden: Finding the right balance. [Abstract]: The national lockdown in India has (thus far) prevented a surge of Covid-19 cases. Due to crowded living conditions and poor social security, infectious spread may be difficult to contain and mitigate. India...
32,762,783
Epidemiol Infect
Emergency management in fever clinic during the outbreak of COVID-19: an experience from Zhuhai.
Coronavirus disease 2019 (COVID-19) is a global health threat. A hospital in Zhuhai adopted several measures in Fever Clinic Management (FCM) to respond to the outbreak of COVID-19. FCM has been proved to be effective in preventing nosocomial cross infection. Faced with the emergency, the hospital undertook creative op...
covid-19;sars-cov-2;emergency management;fever clinic;infection prevention and control
Journal Article;Research Support, Non-U.S. Gov't
Jiang, H;Liu, J W;Ren, N;He, R;Li, M Q;Dong, Q C
10.1017/S0950268820001764
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Emergency management in fever clinic during the outbreak of COVID-19: an experience from Zhuhai. [Abstract]: Coronavirus disease 2019 (COVID-19) is a global health threat. A hospital in Zhuhai adopted several measures in Fever Clinic Management (FCM) to respond to the outbreak of COVID-19. FCM has been proved ...
32,864,128
Clin Transl Immunology
Systematic analysis of disease-specific immunological signatures in patients with febrile illness from Saudi Arabia.
Objectives: Little is known about the prevalence of febrile illness in the Arabian region as clinical, laboratory and immunological profiling remains largely uncharacterised. Methods: A total of 2018 febrile patients from Jazan, Saudi Arabia, were recruited between 2014 and 2017. Patients were screened for dengue and c...
saudi arabia;biomarkers;cytokines;infectious diseases;patients
Journal Article
Kam, Yiu-Wing;Ahmed, Mohamed Yousif;Amrun, Siti Naqiah;Lee, Bernett;Refaie, Tarik;Elgizouli, Kamla;Fong, Siew-Wai;Renia, Laurent;Ng, Lisa Fp
10.1002/cti2.1163
[ 1, 1, 0, 1, 0, 0, 0 ]
[Title]: Systematic analysis of disease-specific immunological signatures in patients with febrile illness from Saudi Arabia. [Abstract]: Objectives: Little is known about the prevalence of febrile illness in the Arabian region as clinical, laboratory and immunological profiling remains largely uncharacterised. Methods...
32,198,005
J Microbiol Immunol Infect
A case of COVID-19 and pneumonia returning from Macau in Taiwan: Clinical course and anti-SARS-CoV-2 IgG dynamic.
A 46-year-old woman presented to the emergency department with 2-day fever and cough at seven days after returning from Macau. COVID-19 and pneumonia was diagnosed based on the positive real-time RT-PCR tests for oropharyngeal swab samples and the presence of anti-SARS-COV-2 IgG starting from the illness day 11 and pos...
covid-19;igg;macau;novel coronavirus;pneumonia;sars-cov-2;serology;taiwan
Case Reports;Journal Article
Lee, Nan-Yao;Li, Chia-Wen;Tsai, Huey-Pin;Chen, Po-Lin;Syue, Ling-Shan;Li, Ming-Chi;Tsai, Chin-Shiang;Lo, Ching-Lung;Hsueh, Po-Ren;Ko, Wen-Chien
10.1016/j.jmii.2020.03.003
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: A case of COVID-19 and pneumonia returning from Macau in Taiwan: Clinical course and anti-SARS-CoV-2 IgG dynamic. [Abstract]: A 46-year-old woman presented to the emergency department with 2-day fever and cough at seven days after returning from Macau. COVID-19 and pneumonia was diagnosed based on the positive...
32,888,800
J Cardiothorac Vasc Anesth
Successful Use of Extracorporeal Membrane Oxygenation Postpartum as Rescue Therapy in a Woman With COVID-19.
Clinical manifestations of coronavirus disease 2019 in pregnant women, in contrast to previous outbreaks, seem to be similar to those of nonpregnant women. During severe acute respiratory syndrome (SARS), SARS influenza A, and Middle East respiratory syndrome outbreaks, an increased severity of disease among pregnant w...
ards;covid-19;extracorporeal membrane oxygenation (ecmo);maternal mortality;postpartum;pregnancy complication
Case Reports
Fiore, Antonio;Piscitelli, Mariantonietta;Adodo, Didier K;Thomas, Charrier;Dessap, Armand Mekontso;Bagate, Francois;Folliguet, Thierry
10.1053/j.jvca.2020.07.088
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Successful Use of Extracorporeal Membrane Oxygenation Postpartum as Rescue Therapy in a Woman With COVID-19. [Abstract]: Clinical manifestations of coronavirus disease 2019 in pregnant women, in contrast to previous outbreaks, seem to be similar to those of nonpregnant women. During severe acute respiratory sy...
32,450,171
Life Sci
Coronaviruses pandemics: Can neutralizing antibodies help?
For the first time in Homo sapiens history, possibly, most of human activities is stopped by coronavirus disease 2019 (COVID-19). Nearly eight billion people of this world are facing a great challenge, maybe not "to be or not to be" yet, but unpredictable. What happens to other major pandemics in the past, and how huma...
antibodies;covid-19;mers-cov;sars-cov;sars-cov-2
Journal Article;Review
Tong, Phuoc-Bao-Viet;Lin, Li-Yun;Tran, Tuan Hiep
10.1016/j.lfs.2020.117836
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Coronaviruses pandemics: Can neutralizing antibodies help? [Abstract]: For the first time in Homo sapiens history, possibly, most of human activities is stopped by coronavirus disease 2019 (COVID-19). Nearly eight billion people of this world are facing a great challenge, maybe not "to be or not to be" yet, bu...
32,695,884
Wellcome Open Res
Historicising "containment and delay": COVID-19, the NHS and high-risk patients.
Despite the first case of the novel coronavirus only being reported to the WHO at the end of December 2019, humanities and social science scholars have been quick to subject local, national and international responses to COVID-19 to critique. Through television and radio, blogs, social media and other outlets, historia...
charles rosenberg;national health service;general practice;health inequalities;pandemics;risk
Journal Article
Moore, Martin D
10.12688/wellcomeopenres.15962.1
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Historicising "containment and delay": COVID-19, the NHS and high-risk patients. [Abstract]: Despite the first case of the novel coronavirus only being reported to the WHO at the end of December 2019, humanities and social science scholars have been quick to subject local, national and international responses ...
32,741,697
Phytomedicine
Antiviral activity of green tea and black tea polyphenols in prophylaxis and treatment of COVID-19: A review.
BACKGROUND: The rapid spread of novel coronavirus called SARS-CoV-2 or nCoV has caused countries all over the world to impose lockdowns and undertake stringent preventive measures. This new positive-sense single-stranded RNA strain of coronavirus spreads through droplets of saliva and nasal discharge. PURPOSE: US FDA h...
covid-19;egcg;sars-cov-2;tea polyphenols;theaflavin
Journal Article;Review
Mhatre, Susmit;Srivastava, Tishya;Naik, Shivraj;Patravale, Vandana
10.1016/j.phymed.2020.153286
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Antiviral activity of green tea and black tea polyphenols in prophylaxis and treatment of COVID-19: A review. [Abstract]: BACKGROUND: The rapid spread of novel coronavirus called SARS-CoV-2 or nCoV has caused countries all over the world to impose lockdowns and undertake stringent preventive measures. This new...
32,371,562
Cleve Clin J Med
Keep cystic fibrosis patients out of the hospital.
No specific data exists regarding management of patients with cystic fibrosis (CF) who are infected with COVID-19. Based on expert opinion, strategies for outpatient management include use of elexacaftor-tezacaftor-ivacaftor to reduce pulmonary exacerbations, telemedicine, adherence to prescribed regimens, prompt and a...
Journal Article
Dasenbrook, Elliot
10.3949/ccjm.87a.ccc005
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Keep cystic fibrosis patients out of the hospital. [Abstract]: No specific data exists regarding management of patients with cystic fibrosis (CF) who are infected with COVID-19. Based on expert opinion, strategies for outpatient management include use of elexacaftor-tezacaftor-ivacaftor to reduce pulmonary exa...
32,794,366
Dermatol Ther
Familial clustering of COVID-19 skin manifestations.
The medical community in the past months has seen a flourishing of information related to the SARS-CoV-2 virus responsible for the COVID-19 pandemic. From the early days of the pandemic, the SARS-CoV-2 virus has been linked to multiple different types of skin involvement. To the best of our knowledge, we are the first ...
covid-19;familial clustering;genetics;immunology;virology
Case Reports;Journal Article
Tatu, Alin Laurentiu;Nadasdy, Thomas;Bujoreanu, Florin Ciprian
10.1111/dth.14181
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Familial clustering of COVID-19 skin manifestations. [Abstract]: The medical community in the past months has seen a flourishing of information related to the SARS-CoV-2 virus responsible for the COVID-19 pandemic. From the early days of the pandemic, the SARS-CoV-2 virus has been linked to multiple different ...
33,021,554
J Addict Med
MOUD Provision in Correctional Settings During Time of COVID-19: Prevention and Solutions.
: Correctional settings can be vectors of infectious diseases due to overcrowding, unsanitary living conditions, and very little capacity to engage in social distancing. In the US, COVID-19 outbreaks were first identified in the New York City and Cook County jails, with infection rates far exceeding community rates. Ea...
Journal Article
Zaller, Nickolas;Brinkley-Rubinstein, Lauren
10.1097/ADM.0000000000000758
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: MOUD Provision in Correctional Settings During Time of COVID-19: Prevention and Solutions. [Abstract]: : Correctional settings can be vectors of infectious diseases due to overcrowding, unsanitary living conditions, and very little capacity to engage in social distancing. In the US, COVID-19 outbreaks were fir...
32,462,289
Curr Oncol Rep
The COVID-19 Pandemic and its Impact on the Cardio-Oncology Population.
PURPOSE OF REVIEW: The novel Coronavirus (2019-nCoV, COVID-19) is historically one of the most severe acute respiratory syndromes and pandemics to affect the globe in the twenty-first century. Originating in Wuhan, the virus rapidly spread and impacted subsets of populations with initial unclear risk factors contributi...
covid-19;cancer;cardio-oncology;cardiovascular disease
Journal Article;Review
Asokan, Ishan;Rabadia, Soniya V;Yang, Eric H
10.1007/s11912-020-00945-4
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The COVID-19 Pandemic and its Impact on the Cardio-Oncology Population. [Abstract]: PURPOSE OF REVIEW: The novel Coronavirus (2019-nCoV, COVID-19) is historically one of the most severe acute respiratory syndromes and pandemics to affect the globe in the twenty-first century. Originating in Wuhan, the virus ra...
32,483,409
Chin Med
The potential insights of Traditional Chinese Medicine on treatment of COVID-19.
Corona Virus Disease 2019 (COVID-19) broke out in 2019 and spread rapidly around the world. There is still no specific antiviral therapy to the current pandemic. In China, historical records show that Traditional Chinese Medicine (TCM) is effective in prevention and enhancing the resistance to pandemic with unique insi...
covid-19;mechanism;sars-cov-2;traditional chinese medicine;treatment
Journal Article
Tong, Tong;Wu, Ying-Qi;Ni, Wei-Jian;Shen, Ai-Zong;Liu, Sheng
10.1186/s13020-020-00326-w
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: The potential insights of Traditional Chinese Medicine on treatment of COVID-19. [Abstract]: Corona Virus Disease 2019 (COVID-19) broke out in 2019 and spread rapidly around the world. There is still no specific antiviral therapy to the current pandemic. In China, historical records show that Traditional Chine...
32,643,410
Nat Prod Res
Bioactive compounds from marine resources against novel corona virus (2019-nCoV): in silico study for corona viral drug.
Present research reports the molecular docking analysis of 2019-nCoV inhibition by antiviral compounds from marine natural resources. For this study, the structure of ligand (antiviral compound) and 2019-nCoV main protease (M(pro)) was received from the databases of PubChem and Protein Data Bank (PDB), respectively. Mo...
2019-ncov;antiviral drug;bioactive compounds;esculetin ethyl ester
Journal Article
Vijayaraj, R;Altaff, K;Rosita, A Sherlin;Ramadevi, S;Revathy, J
10.1080/14786419.2020.1791115
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Bioactive compounds from marine resources against novel corona virus (2019-nCoV): in silico study for corona viral drug. [Abstract]: Present research reports the molecular docking analysis of 2019-nCoV inhibition by antiviral compounds from marine natural resources. For this study, the structure of ligand (ant...
32,761,402
Abdom Radiol (NY)
Abdominopelvic CT findings in patients with novel coronavirus disease 2019 (COVID-19).
PURPOSE: Some patients with novel coronavirus disease 2019 (COVID-2019) present with abdominal symptoms. Abdominal manifestations of COVID on imaging are not yet established. The goal of this study was to quantify the frequency of positive findings on abdominopelvic CT in COVID-positive patients, and to identify clinic...
covid-19;coronavirus;pandemic;sars-cov-2
Journal Article
Goldberg-Stein, Shlomit;Fink, Adam;Paroder, Viktoriya;Kobi, Mariya;Yee, Judy;Chernyak, Victoria
10.1007/s00261-020-02669-2
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Abdominopelvic CT findings in patients with novel coronavirus disease 2019 (COVID-19). [Abstract]: PURPOSE: Some patients with novel coronavirus disease 2019 (COVID-2019) present with abdominal symptoms. Abdominal manifestations of COVID on imaging are not yet established. The goal of this study was to quantif...
32,249,943
J Med Virol
A comparative-descriptive analysis of clinical characteristics in 2019-coronavirus-infected children and adults.
Acute respiratory disease caused by 2019 novel coronavirus (2019-nCoV) has rapidly spread throughout China. Children and adults show a different clinical course. The purpose of the current study is to comparatively analyze the clinical characteristics of 2019-nCoV infection in children and adults and to explore the pos...
2019 novel coronavirus;clinical manifestations;comparative analysis;differences between children and adults;laboratory parameters
Journal Article
Han, Ya-Nan;Feng, Zhan-Wei;Sun, Li-Na;Ren, Xiao-Xia;Wang, Hua;Xue, Yong-Ming;Wang, Yi;Fang, Ying
10.1002/jmv.25835
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: A comparative-descriptive analysis of clinical characteristics in 2019-coronavirus-infected children and adults. [Abstract]: Acute respiratory disease caused by 2019 novel coronavirus (2019-nCoV) has rapidly spread throughout China. Children and adults show a different clinical course. The purpose of the curre...
32,490,887
Braz Oral Res
Investigation of Turkish dentists' clinical attitudes and behaviors towards the COVID-19 pandemic: a survey study.
Currently, the whole world is under the threat of the COVID-19 pandemic, and dentists are at high risk. The aim of this study was to investigate what kind of precautions Turkish dentists take in dental clinics during the COVID-19 pandemic. The study population consisted of dentists in Turkey. An online questionnaire (2...
Journal Article
Duruk, Gulsum;Gumusboga, Zekiye Seyma;Colak, Cemil
10.1590/1807-3107bor-2020.vol34.0054
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Investigation of Turkish dentists' clinical attitudes and behaviors towards the COVID-19 pandemic: a survey study. [Abstract]: Currently, the whole world is under the threat of the COVID-19 pandemic, and dentists are at high risk. The aim of this study was to investigate what kind of precautions Turkish dentis...
32,436,622
J Gastroenterol Hepatol
Metabolic associated fatty liver disease increases coronavirus disease 2019 disease severity in nondiabetic patients.
BACKGROUND AND AIM: Coronavirus disease 2019 (COVID-19) has attracted increasing worldwide attention. While diabetes is known to aggravate COVID-19 severity, it is not known whether nondiabetic patients with metabolic dysfunction are also more prone to more severe disease. The association of metabolic associated fatty ...
covid-19;metabolic associated fatty liver disease;nondiabetes
Journal Article
Gao, Feng;Zheng, Kenneth I;Wang, Xiao-Bo;Yan, Hua-Dong;Sun, Qing-Feng;Pan, Ke-Hua;Wang, Ting-Yao;Chen, Yong-Ping;George, Jacob;Zheng, Ming-Hua
10.1111/jgh.15112
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Metabolic associated fatty liver disease increases coronavirus disease 2019 disease severity in nondiabetic patients. [Abstract]: BACKGROUND AND AIM: Coronavirus disease 2019 (COVID-19) has attracted increasing worldwide attention. While diabetes is known to aggravate COVID-19 severity, it is not known whether...
32,997,488
ACS Chem Neurosci
Chemosensory Dysfunction in COVID-19: Integration of Genetic and Epidemiological Data Points to D614G Spike Protein Variant as a Contributing Factor.
After several months of rapid pandemic expansion, it is now apparent that the SARS-CoV-2 coronavirus interferes with smell and taste sensation in a substantial proportion of COVID-19 patients. Recent epidemiological data documented intriguing differences in prevalence of chemosensory dysfunctions between different worl...
ace2;covid-19;chemosensory dysfunction;d614g mutation;d614g variant;olfactory dysfunction
Journal Article;Review
Butowt, Rafal;Bilinska, Katarzyna;Von Bartheld, Christopher S
10.1021/acschemneuro.0c00596
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Chemosensory Dysfunction in COVID-19: Integration of Genetic and Epidemiological Data Points to D614G Spike Protein Variant as a Contributing Factor. [Abstract]: After several months of rapid pandemic expansion, it is now apparent that the SARS-CoV-2 coronavirus interferes with smell and taste sensation in a s...
32,503,668
Crit Care
Neutrophil-to-lymphocyte ratio as a predictive biomarker for moderate-severe ARDS in severe COVID-19 patients.
TRIAL REGISTRATION: ChiCTR, ChiCTR2000029758. Registered 12 February 2020 - Retrospectively registered.
Clinical Trial;Letter;Research Support, Non-U.S. Gov't
Ma, Aijia;Cheng, Jiangli;Yang, Jing;Dong, Meiling;Liao, Xuelian;Kang, Yan
10.1186/s13054-020-03007-0
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Neutrophil-to-lymphocyte ratio as a predictive biomarker for moderate-severe ARDS in severe COVID-19 patients. [Abstract]: TRIAL REGISTRATION: ChiCTR, ChiCTR2000029758. Registered 12 February 2020 - Retrospectively registered. [Keywords]:
32,954,592
J Intellect Disabil Res
Impact of the initial response to COVID-19 on long-term care for people with intellectual disability: an interrupted time series analysis of incident reports.
BACKGROUND: The lockdown-measures in response to COVID-19 taken by long-term care organisations might have impacted problem behaviour and behavioural functioning of people with intellectual disability. This study tested changes in reported incidents, in particular regarding aggression, unexplained absence and, for cont...
covid-19;administrative data;aggression;incident reports;long term care;people with intellectual disability
Journal Article
Schuengel, C;Tummers, J;Embregts, P J C M;Leusink, G L
10.1111/jir.12778
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of the initial response to COVID-19 on long-term care for people with intellectual disability: an interrupted time series analysis of incident reports. [Abstract]: BACKGROUND: The lockdown-measures in response to COVID-19 taken by long-term care organisations might have impacted problem behaviour and be...
32,835,066
Radiol Infect Dis
Clinical and CT characteristics which indicate timely radiological reexamination in patients with COVID-19: A retrospective study in Beijing, China.
Objective: Chest CT is useful in assessing the disease course of coronavirus disease-19 (COVID-19). This study aims to identify the characteristics of patients in whom imaging progression occurred while clinical symptoms were relieved and to guide radiological reexamination. Methods: This retrospective study included 7...
computed tomography;coronavirus disease-19;prognosis
Journal Article
Li, Xueqin;Pan, Ziang;Xia, Zhenying;Li, Ruili;Wang, Xing;Zhang, Ruichi;Li, Hongjun
10.1016/j.jrid.2020.05.003
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical and CT characteristics which indicate timely radiological reexamination in patients with COVID-19: A retrospective study in Beijing, China. [Abstract]: Objective: Chest CT is useful in assessing the disease course of coronavirus disease-19 (COVID-19). This study aims to identify the characteristics of...
32,730,212
IEEE Trans Med Imaging
Dual-Sampling Attention Network for Diagnosis of COVID-19 From Community Acquired Pneumonia.
The coronavirus disease (COVID-19) is rapidly spreading all over the world, and has infected more than 1,436,000 people in more than 200 countries and territories as of April 9, 2020. Detecting COVID-19 at early stage is essential to deliver proper healthcare to the patients and also to protect the uninfected populatio...
Journal Article
Ouyang, Xi;Huo, Jiayu;Xia, Liming;Shan, Fei;Liu, Jun;Mo, Zhanhao;Yan, Fuhua;Ding, Zhongxiang;Yang, Qi;Song, Bin;Shi, Feng;Yuan, Huan;Wei, Ying;Cao, Xiaohuan;Gao, Yaozong;Wu, Dijia;Wang, Qian;Shen, Dinggang
10.1109/TMI.2020.2995508
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Dual-Sampling Attention Network for Diagnosis of COVID-19 From Community Acquired Pneumonia. [Abstract]: The coronavirus disease (COVID-19) is rapidly spreading all over the world, and has infected more than 1,436,000 people in more than 200 countries and territories as of April 9, 2020. Detecting COVID-19 at ...
32,994,343
Proc Natl Acad Sci U S A
Experimental infection of domestic dogs and cats with SARS-CoV-2: Pathogenesis, transmission, and response to reexposure in cats.
The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has reached nearly every country in the world with extraordinary person-to-person transmission. The most likely original source of the virus was spillover from an animal reservoir and subsequent adaptation to humans sometime during the ...
sars-cov-2;cats;experimental infection;transmission
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Bosco-Lauth, Angela M;Hartwig, Airn E;Porter, Stephanie M;Gordy, Paul W;Nehring, Mary;Byas, Alex D;VandeWoude, Sue;Ragan, Izabela K;Maison, Rachel M;Bowen, Richard A
10.1073/pnas.2013102117
[ 0, 0, 0, 1, 1, 0, 0 ]
[Title]: Experimental infection of domestic dogs and cats with SARS-CoV-2: Pathogenesis, transmission, and response to reexposure in cats. [Abstract]: The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has reached nearly every country in the world with extraordinary person-to-person tra...
32,970,661
MMWR Morb Mortal Wkly Rep
Update: Characteristics of Health Care Personnel with COVID-19 - United States, February 12-July 16, 2020.
As of September 21, 2020, the coronavirus disease 2019 (COVID-19) pandemic had resulted in 6,786,352 cases and 199,024 deaths in the United States.* Health care personnel (HCP) are essential workers at risk for exposure to patients or infectious materials (1). The impact of COVID-19 on U.S. HCP was first described usin...
Journal Article
Hughes, Michelle M;Groenewold, Matthew R;Lessem, Sarah E;Xu, Kerui;Ussery, Emily N;Wiegand, Ryan E;Qin, Xiaoting;Do, Tuyen;Thomas, Deepam;Tsai, Stella;Davidson, Alexander;Latash, Julia;Eckel, Seth;Collins, Jim;Ojo, Mojisola;McHugh, Lisa;Li, Wenhui;Chen, Judy;Chan, Jonathan;Wortham, Jonathan M;Reagan-Steiner, Sarah;Lee,...
10.15585/mmwr.mm6938a3
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Update: Characteristics of Health Care Personnel with COVID-19 - United States, February 12-July 16, 2020. [Abstract]: As of September 21, 2020, the coronavirus disease 2019 (COVID-19) pandemic had resulted in 6,786,352 cases and 199,024 deaths in the United States.* Health care personnel (HCP) are essential w...
32,277,408
Infection
First case of COVID-19 complicated with fulminant myocarditis: a case report and insights.
BACKGROUND: Coronavirus disease 2019 (COVID-19) has been demonstrated to be the cause of pneumonia. Nevertheless, it has not been reported as the cause of acute myocarditis or fulminant myocarditis. CASE PRESENTATION: A 63-year-old male was admitted with pneumonia and cardiac symptoms. He was genetically confirmed as h...
covid-19;coronavirus;echocardiography;fulminant myocarditis;infection
Case Reports;Journal Article
Zeng, Jia-Hui;Liu, Ying-Xia;Yuan, Jing;Wang, Fu-Xiang;Wu, Wei-Bo;Li, Jin-Xiu;Wang, Li-Fei;Gao, Hong;Wang, Yao;Dong, Chang-Feng;Li, Yi-Jun;Xie, Xiao-Juan;Feng, Cheng;Liu, Lei
10.1007/s15010-020-01424-5
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: First case of COVID-19 complicated with fulminant myocarditis: a case report and insights. [Abstract]: BACKGROUND: Coronavirus disease 2019 (COVID-19) has been demonstrated to be the cause of pneumonia. Nevertheless, it has not been reported as the cause of acute myocarditis or fulminant myocarditis. CASE PRES...
32,745,895
Eur J Radiol
Role of computed tomography in predicting critical disease in patients with covid-19 pneumonia: A retrospective study using a semiautomatic quantitative method.
BACKGROUND: So far, only a few studies evaluated the correlation between CT features and clinical outcome in patients with COVID-19 pneumonia. PURPOSE: To evaluate CT ability in differentiating critically ill patients requiring invasive ventilation from patients with less severe disease. METHODS: We retrospectively col...
covid-19;invasive mechanical ventilation;lung volume;pneumonia;quantitative ct;sars- cov-2
Evaluation Study;Journal Article
Leonardi, Andrea;Scipione, Roberto;Alfieri, Giulia;Petrillo, Roberta;Dolciami, Miriam;Ciccarelli, Fabio;Perotti, Stefano;Cartocci, Gaia;Scala, Annarita;Imperiale, Carmela;Iafrate, Franco;Francone, Marco;Catalano, Carlo;Ricci, Paolo
10.1016/j.ejrad.2020.109202
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Role of computed tomography in predicting critical disease in patients with covid-19 pneumonia: A retrospective study using a semiautomatic quantitative method. [Abstract]: BACKGROUND: So far, only a few studies evaluated the correlation between CT features and clinical outcome in patients with COVID-19 pneumo...
32,963,564
Evid Based Complement Alternat Med
Tea Polyphenols EGCG and Theaflavin Inhibit the Activity of SARS-CoV-2 3CL-Protease In Vitro.
COVID-19, a global pandemic, has caused over 750,000 deaths worldwide as of August 2020. A vaccine or remedy for SARS-CoV-2, the virus responsible for COVID-19, is necessary to slow down the spread and lethality of COVID-19. However, there is currently no effective treatment available against SARS-CoV-2. In this report...
Journal Article
Jang, Minsu;Park, Yea-In;Cha, Yeo-Eun;Park, Rackhyun;Namkoong, Sim;Lee, Jin I;Park, Junsoo
10.1155/2020/5630838
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Tea Polyphenols EGCG and Theaflavin Inhibit the Activity of SARS-CoV-2 3CL-Protease In Vitro. [Abstract]: COVID-19, a global pandemic, has caused over 750,000 deaths worldwide as of August 2020. A vaccine or remedy for SARS-CoV-2, the virus responsible for COVID-19, is necessary to slow down the spread and let...
32,543,703
Clin Sci (Lond)
SARS-CoV2 may evade innate immune response, causing uncontrolled neutrophil extracellular traps formation and multi-organ failure.
We demonstrate that the general clinical conditions, risk factors and numerous pathological and biological features of COVID-19 are analogous with various disorders caused by the uncontrolled formation of neutrophil extracellular traps and their by-products. Given the rapid evolution of this disease's symptoms and its ...
covid19;neutrophil;traps;circulating dna;pathogenesis
Journal Article;Research Support, Non-U.S. Gov't
Thierry, Alain R;Roch, Benoit
10.1042/CS20200531
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: SARS-CoV2 may evade innate immune response, causing uncontrolled neutrophil extracellular traps formation and multi-organ failure. [Abstract]: We demonstrate that the general clinical conditions, risk factors and numerous pathological and biological features of COVID-19 are analogous with various disorders cau...
32,984,837
Crit Care Explor
Disseminated Multifocal Intracerebral Bleeding Events in Three Coronavirus Disease 2019 Patients on Extracorporeal Membrane Oxygenation As Rescue Therapy.
Objectives: To describe three coronavirus disease 2019 patients suffering from acute respiratory distress syndrome under venovenous extracorporeal membrane oxygenation therapy and tight anticoagulation monitoring presenting a novel pattern of multifocal brain hemorrhage in various degrees in all cerebral and cerebellar...
acute respiratory distress syndrome;cerebral microhemorrhage;coronavirus disease 2019;extracorporeal membrane oxygenation;intracerebral bleeding
Journal Article
Bihlmaier, Karl;Coras, Roland;Willam, Carsten;Grampp, Steffen;Jabari, Samir;Eichhorn, Philip;Haller, Florian;Kuramatsu, Joji;Schwab, Stefan;Castellanos, Ixchel;Birkholz, Torsten;Schuttler, Jurgen;Altmeppen, Jurgen;Schiffer, Mario;Herbst, Larissa
10.1097/CCE.0000000000000218
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Disseminated Multifocal Intracerebral Bleeding Events in Three Coronavirus Disease 2019 Patients on Extracorporeal Membrane Oxygenation As Rescue Therapy. [Abstract]: Objectives: To describe three coronavirus disease 2019 patients suffering from acute respiratory distress syndrome under venovenous extracorpore...
32,385,891
Dermatol Ther
Systemic immunobiological, immunosuppressant, and oncologic agents for the treatment of dermatologic diseases during the SARS-CoV-2 (COVID-19) pandemic emergency: A quick review for a quick consultation.
The precision medicine era has helped to better manage patients with immunological and oncological diseases, improving the quality of life of this class of patients. Regarding the management of these patients and positivity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), currently, limited data are ava...
covid-19;sars-cov-2;biologics;dermatologic treatments;immunosuppressants;skin disease;therapy systemic
Journal Article;Review
Paolino, Giovanni;Mercuri, Santo Raffaele;Bearzi, Pietro;Mattozzi, Carlo
10.1111/dth.13537
[ 1, 0, 1, 1, 0, 0, 0 ]
[Title]: Systemic immunobiological, immunosuppressant, and oncologic agents for the treatment of dermatologic diseases during the SARS-CoV-2 (COVID-19) pandemic emergency: A quick review for a quick consultation. [Abstract]: The precision medicine era has helped to better manage patients with immunological and oncologi...
33,019,663
Vaccines (Basel)
Relationship between Citizens' Health Engagement and Intention to Take the COVID-19 Vaccine in Italy: A Mediation Analysis.
The actual effectiveness of the still-to-come vaccination against the coronavirus SARS-CoV-2 might be challenged by vaccine hesitancy, a rather common and known phenomenon whose psychological predictors are, nevertheless, still largely debated. Our study aims at understanding how adult citizens' health engagement, perc...
covid-19;sars-cov-2;health engagement;mediation model;path model;patient engagement;vaccine acceptance;vaccine attitude;vaccine hesitancy
Journal Article
Graffigna, Guendalina;Palamenghi, Lorenzo;Boccia, Stefania;Barello, Serena
10.3390/vaccines8040576
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Relationship between Citizens' Health Engagement and Intention to Take the COVID-19 Vaccine in Italy: A Mediation Analysis. [Abstract]: The actual effectiveness of the still-to-come vaccination against the coronavirus SARS-CoV-2 might be challenged by vaccine hesitancy, a rather common and known phenomenon who...
32,836,371
Int Rev Educ
Adult learning and education as a tool to contain pandemics: The COVID-19 experience.
In combating pandemics, more can be gained by changing citizens' behaviours than by relying solely on the medical route. In the current COVID-19 pandemic, the struggle to contain the outbreak and push back new infection figures will ultimately be won by training citizens how to avoid creating secondary transmission cha...
covid-19;adult education;adult learning;advocacy;health campaigns;health literacy;pandemics
Journal Article
Lopes, Henrique;McKay, Veronica
10.1007/s11159-020-09843-0
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Adult learning and education as a tool to contain pandemics: The COVID-19 experience. [Abstract]: In combating pandemics, more can be gained by changing citizens' behaviours than by relying solely on the medical route. In the current COVID-19 pandemic, the struggle to contain the outbreak and push back new inf...
32,880,667
Pediatr Cardiol
From Other Journals: A Review of Recent Articles in Pediatric Cardiology.
In this review, we provide a brief description of recently published articles addressing topics relevant to pediatric cardiologists. Our hope is to provide a summary of the latest articles published recently in other journals in our field. The articles address (1) pulmonary valve repair in patients with tetralogy of Fa...
adults with congenital heart disease;heart transplantation;marfan syndrome;multisystem inflammatory syndrome in children;pulmonary valve repair;tetralogy of fallot
Journal Article;Review
Alsaied, Tarek;Ashfaq, Awais
10.1007/s00246-020-02443-7
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: From Other Journals: A Review of Recent Articles in Pediatric Cardiology. [Abstract]: In this review, we provide a brief description of recently published articles addressing topics relevant to pediatric cardiologists. Our hope is to provide a summary of the latest articles published recently in other journals...
32,729,142
Cancer
COVID-19 outcomes of patients with gynecologic cancer in New York City.
BACKGROUND: New York City (NYC) is the epicenter of severe acute respiratory syndrome coronavirus 2 (coronavirus disease 2019 [COVID-19]) in the United States. Clinical characteristics and outcomes of vulnerable populations, such as those with gynecologic cancer who develop COVID-19 infections, is limited. METHODS: Pat...
coronavirus disease 2019 (covid-19);gynecologic cancer;outcomes;severe acute respiratory syndrome coronavirus 2 (sars-cov-2)
Journal Article;Multicenter Study;Observational Study;Research Support, N.I.H., Extramural
Lara, Olivia D;O'Cearbhaill, Roisin E;Smith, Maria J;Sutter, Megan E;Knisely, Anne;McEachron, Jennifer;Gabor, Lisa R;Jee, Justin;Fehniger, Julia E;Lee, Yi-Chun;Isani, Sara S;Wright, Jason D;Pothuri, Bhavana
10.1002/cncr.33084
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 outcomes of patients with gynecologic cancer in New York City. [Abstract]: BACKGROUND: New York City (NYC) is the epicenter of severe acute respiratory syndrome coronavirus 2 (coronavirus disease 2019 [COVID-19]) in the United States. Clinical characteristics and outcomes of vulnerable populations, su...
32,490,972
Arq Bras Oftalmol
COVID-19 and the eye: how much do we really know? A best evidence review.
To identify and classify available information regarding COVID-19 and eye care according to the level of evidence, within four main topics of interest: evidence of the virus in tears and the ocular surface, infection via the conjunctival route, ocular manifestations, and best practice recommendations. A structured revi...
Journal Article;Review
Emparan, Juan Pablo Olivares-de;Sardi-Correa, Carolina;Lopez-Ulloa, Juan Alberto;Viteri-Soria, Jaime;Penniecook, Jason A;Jimenez-Roman, Jesus;Lansingh, Van C
10.5935/0004-2749.20200067
[ 0, 1, 1, 0, 1, 0, 0 ]
[Title]: COVID-19 and the eye: how much do we really know? A best evidence review. [Abstract]: To identify and classify available information regarding COVID-19 and eye care according to the level of evidence, within four main topics of interest: evidence of the virus in tears and the ocular surface, infection via the ...
32,856,817
Probl Sotsialnoi Gig Zdravookhranenniiai Istor Med
[MANAGEMENT ASPECTS OF PROFESSIONAL SAFETY OF MEDICAL PERSONNEL IN BUDGETARY HEALTH OF RUSSIA].
The study examines the issues of assessing the impact on occupational safety of public health workers of psycho-emotional factors associated with the provision of medical services and the socio-economic and industrial conditions of their work. As the analysis conducted by the authors on the basis of foreign sources sho...
budget healthcare;occupational burnout;occupational safety of medical workers
Journal Article
Dolzhenkova, Yu V;Kamneva, E V;Safonov, A L;Zappala, S
10.32687/0869-866X-2020-28-s1-736-740
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [MANAGEMENT ASPECTS OF PROFESSIONAL SAFETY OF MEDICAL PERSONNEL IN BUDGETARY HEALTH OF RUSSIA]. [Abstract]: The study examines the issues of assessing the impact on occupational safety of public health workers of psycho-emotional factors associated with the provision of medical services and the socio-economic ...
32,629,121
Clin Gastroenterol Hepatol
Increased Internet Search Interest for GI Symptoms May Predict COVID-19 Cases in US Hotspots.
Google Trends is an online tool that allows measurement of search term popularity on Google, spatially and temporally. While not an epidemiological tool for determining incidence, it can estimate the popularity of a certain disease by search volume over time.(1)(,)(2) It has previously correlated well with infectious d...
Journal Article;Multicenter Study
Ahmad, Imama;Flanagan, Ryan;Staller, Kyle
10.1016/j.cgh.2020.06.058
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: Increased Internet Search Interest for GI Symptoms May Predict COVID-19 Cases in US Hotspots. [Abstract]: Google Trends is an online tool that allows measurement of search term popularity on Google, spatially and temporally. While not an epidemiological tool for determining incidence, it can estimate the popul...
32,857,119
Am J Clin Pathol
COVID-19 Testing.
OBJECTIVES: To illustrate how patient risk and clinical costs are driven by false-positive and false-negative results. METHODS: Molecular, antigen, and antibody testing are the mainstay to identify infected patients and fight the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). To evaluate the test methods...
clinical;covid-19;coronavirus;cost;false-negative;false-positive;metrics;prevalence;risk;sars-cov-2;sensitivity;specificity
Journal Article
Brooks, Zoe C;Das, Saswati
10.1093/ajcp/aqaa141
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 Testing. [Abstract]: OBJECTIVES: To illustrate how patient risk and clinical costs are driven by false-positive and false-negative results. METHODS: Molecular, antigen, and antibody testing are the mainstay to identify infected patients and fight the severe acute respiratory syndrome coronavirus 2 (SA...
32,864,837
Appl Psychol Health Well Being
Belief in COVID-19 Conspiracy Theories Reduces Social Distancing over Time.
BACKGROUND: Conspiracy theories about the origins of COVID-19 are widespread and have even been propagated by highly ranked state officials and politicians in the US. Health authorities have cautioned that such theories, although not questioning the existence of the pandemic, may increase the spread of the virus by red...
covid-19;conspiracy theories;longitudinal;social distancing
Journal Article
Bierwiaczonek, Kinga;Kunst, Jonas R;Pich, Olivia
10.1111/aphw.12223
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Belief in COVID-19 Conspiracy Theories Reduces Social Distancing over Time. [Abstract]: BACKGROUND: Conspiracy theories about the origins of COVID-19 are widespread and have even been propagated by highly ranked state officials and politicians in the US. Health authorities have cautioned that such theories, al...
32,929,416
JTO Clin Res Rep
Real-World Scenario of Patients With Lung Cancer Amid the Coronavirus Disease 2019 Pandemic in the People's Republic of China.
Introduction: The coronavirus disease 2019 (COVID-19) outbreak throughout the world has affected millions of people in many ways, putting a huge burden on the health care system. The ongoing outbreak of this respiratory disease has posed critical challenges to public health, research, and medical communities around the...
coronavirus disease 2019;lung cancer;pandemic;severe acute respiratory syndrome coronavirus 2
Journal Article
Fu, Rui;Wu, Lin;Zhang, Chao;Chu, Qian;Hu, Jie;Lin, Gen;Yang, Lin;Li, Ji-Sheng;Yang, Xue-Ning;Yang, Jin-Ji;Zhou, Qing;Wu, Yi-Long;Zhong, Wen-Zhao
10.1016/j.jtocrr.2020.100053
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Real-World Scenario of Patients With Lung Cancer Amid the Coronavirus Disease 2019 Pandemic in the People's Republic of China. [Abstract]: Introduction: The coronavirus disease 2019 (COVID-19) outbreak throughout the world has affected millions of people in many ways, putting a huge burden on the health care s...
32,933,522
J Transl Med
Correlation of the two most frequent HLA haplotypes in the Italian population to the differential regional incidence of Covid-19.
BACKGROUND: Understanding how HLA polymorphisms may affect both susceptibility, course and severity of Covid-19 infection could help both at the clinical level to identify individuals at higher risk from the disease and at the epidemiological one to explain the differences in the epidemic trend among countries or even ...
covid-19 incidence and mortality;hla polymorphisms;hla typing;susceptibility
Journal Article;Research Support, Non-U.S. Gov't
Pisanti, Simona;Deelen, Joris;Gallina, Anna Maria;Caputo, Mariella;Citro, Marianna;Abate, Mario;Sacchi, Nicoletta;Vecchione, Carmine;Martinelli, Rosanna
10.1186/s12967-020-02515-5
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Correlation of the two most frequent HLA haplotypes in the Italian population to the differential regional incidence of Covid-19. [Abstract]: BACKGROUND: Understanding how HLA polymorphisms may affect both susceptibility, course and severity of Covid-19 infection could help both at the clinical level to identi...
33,061,829
Mediators Inflamm
Distinguishable Immunologic Characteristics of COVID-19 Patients with Comorbid Type 2 Diabetes Compared with Nondiabetic Individuals.
Background: COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has threatened every civilian as a global pandemic. The immune system poses the critical interactive chain between the human body and the virus. Here, we make efforts to examine whether comorbidity with type 2 diabetes (T2D) aff...
Journal Article
Zhao, Ruxing;Sun, Yujing;Zhang, Yongyuan;Wang, Weili;Wang, Shouyu;Wang, Chuang;Liu, Jinbo;Gao, Ling;Hu, Zhao;Fei, Jianchun;Hou, Xinguo;Zheng, Huizhen;Chen, Li
10.1155/2020/6914878
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Distinguishable Immunologic Characteristics of COVID-19 Patients with Comorbid Type 2 Diabetes Compared with Nondiabetic Individuals. [Abstract]: Background: COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has threatened every civilian as a global pandemic. The immune system pos...
32,987,033
Virus Res
Transcription-based drug repurposing for COVID-19.
We have utilised the transcriptional response of lung epithelial cells following infection by the original Severe Acute Respiratory Syndrome coronavirus (SARS) to identify repurposable drugs for COVID-19. Drugs best able to recapitulate the infection profile are highly enriched for antiviral activity. Nine of these hav...
covid-19;gene expression;repurposing
Journal Article
Killick, Richard;Ballard, Clive;Doherty, Patrick;Williams, Gareth
10.1016/j.virusres.2020.198176
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Transcription-based drug repurposing for COVID-19. [Abstract]: We have utilised the transcriptional response of lung epithelial cells following infection by the original Severe Acute Respiratory Syndrome coronavirus (SARS) to identify repurposable drugs for COVID-19. Drugs best able to recapitulate the infecti...
32,407,937
Thromb Res
The clinical implication of dynamic neutrophil to lymphocyte ratio and D-dimer in COVID-19: A retrospective study in Suzhou China.
OBJECTIVE: To investigate the clinical features of COVID-19 cases in Suzhou China. Biomarkers were screened out of hematological parameters for risk stratification. METHOD: Confirmed COVID-19 adult patients in Suzhou were included. The patient data was collected, and the results of laboratory examinations were compared...
coronavirus disease 2019;d-dimer;neutrophil to lymphocyte ratio
Comparative Study;Journal Article
Fu, Jianhong;Kong, Jindan;Wang, Wei;Wu, Meiying;Yao, Lin;Wang, Zhaoyue;Jin, Jun;Wu, Depei;Yu, Xin
10.1016/j.thromres.2020.05.006
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: The clinical implication of dynamic neutrophil to lymphocyte ratio and D-dimer in COVID-19: A retrospective study in Suzhou China. [Abstract]: OBJECTIVE: To investigate the clinical features of COVID-19 cases in Suzhou China. Biomarkers were screened out of hematological parameters for risk stratification. MET...
32,717,052
Clin Infect Dis
SARS-CoV-2 in rural Latin America. A population-based study in coastal Ecuador.
Antibodies to SARS-CoV-2 were detected in 303/673 rural Ecuadorian adults (45%), 77% of whom had compatible clinical manifestations. Seropositivity was associated with the use of open latrines. Our findings support the fears of mass spread of SARS-CoV-2 in rural Latin America and cannot exclude a contributing role for ...
covid-19;coronavirus-19;ecuador;population study;rural setting;sars-cov-2
Journal Article
Del Brutto, Oscar H;Costa, Aldo F;Mera, Robertino M;Recalde, Bettsy Y;Bustos, Javier A;Garcia, Hector H
10.1093/cid/ciaa1055
[ 0, 1, 0, 0, 1, 0, 0 ]
[Title]: SARS-CoV-2 in rural Latin America. A population-based study in coastal Ecuador. [Abstract]: Antibodies to SARS-CoV-2 were detected in 303/673 rural Ecuadorian adults (45%), 77% of whom had compatible clinical manifestations. Seropositivity was associated with the use of open latrines. Our findings support the ...
32,393,973
Inflamm Bowel Dis
Management of Acute Severe Ulcerative Colitis in a Pregnant Woman With COVID-19 Infection: A Case Report and Review of the Literature.
First detected in Wuhan, China, the novel 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped RNA beta-coronavirus responsible for an unprecedented, worldwide pandemic caused by COVID-19. Optimal management of immunosuppression in inflammatory bowel disease (IBD) patients with COVID-19 inf...
covid-19;coronavirus;cyclosporine;inflammatory bowel disease;pregnancy;ulcerative colitis
Case Reports;Journal Article;Review
Rosen, Melissa H;Axelrad, Jordan;Hudesman, David;Rubin, David T;Chang, Shannon
10.1093/ibd/izaa109
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Management of Acute Severe Ulcerative Colitis in a Pregnant Woman With COVID-19 Infection: A Case Report and Review of the Literature. [Abstract]: First detected in Wuhan, China, the novel 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped RNA beta-coronavirus responsible for an ...
32,911,555
Am J Perinatol
Beyond the First Wave: Consequences of COVID-19 on High-Risk Infants and Families.
The novel coronavirus disease 2019 (COVID-19) pandemic is affecting care for high-risk newborns in ways that will likely be sustained beyond the initial pandemic response. These novel challenges present an urgent imperative to understand how COVID-19 impacts parent, family, and infant outcomes. We highlight three areas...
Journal Article
Lemmon, Monica E;Chapman, Ira;Malcolm, William;Kelley, Kelli;Shaw, Richard J;Milazzo, Angelo;Cotten, C Michael;Hintz, Susan R
10.1055/s-0040-1715839
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Beyond the First Wave: Consequences of COVID-19 on High-Risk Infants and Families. [Abstract]: The novel coronavirus disease 2019 (COVID-19) pandemic is affecting care for high-risk newborns in ways that will likely be sustained beyond the initial pandemic response. These novel challenges present an urgent imp...