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32,547,309
Int J Med Sci
Characteristics of in peripheral blood of 70 hospitalized patients and 8 diarrhea patients with COVID-19.
Objective: To analyze the blood test indicators of patients after infection of COVID-19 in Chongqing and analyze the clinical indicators of 8 patients with diarrhea. Materials and Methods: From January 26, 2019 to February 13, 2020, 70 patients diagnosed with 2019-nCoV according to the World Health Organization interim...
covid-19;diarrhea;ggt;peripheral blood
Journal Article
Wei, Xiao-Yu;Jing, Ding;Jia, Bei;Li, Qing;Zhou, Xia-Qia;Gong, Ming-Feng;Zou, Jing-Bo;Zhang, Qiang;Huang, Wen-Xiang;Tian, Wen-Guang
10.7150/ijms.45743
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Characteristics of in peripheral blood of 70 hospitalized patients and 8 diarrhea patients with COVID-19. [Abstract]: Objective: To analyze the blood test indicators of patients after infection of COVID-19 in Chongqing and analyze the clinical indicators of 8 patients with diarrhea. Materials and Methods: From...
32,891,579
An Pediatr (Barc)
[COVID-19 and Africa: Surviving between a rock and a hard place].
With over 575,000 deaths and about 13.3 million cases globally, the COVID-19 pandemic has had a terrible impact globally during the 6 months since cases were first detected in China. Conscious of the many challenges presented in settings with abundance of resources and with robust health systems, where mortality has be...
africa;covid-19;epidemiology;epidemiologia;low-income countries;pandemia;pandemic;paises de baja renta;africa
Journal Article
de Aranzabal, Maite;Fumado, Victoria;Alegria, Inaki;Rivera, Mercedes;Torre, Nuria;Guibert, Belen;Munoz, Maria Jose;Moraleda, Cinta;Bassat, Quique
10.1016/j.anpedi.2020.07.007
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [COVID-19 and Africa: Surviving between a rock and a hard place]. [Abstract]: With over 575,000 deaths and about 13.3 million cases globally, the COVID-19 pandemic has had a terrible impact globally during the 6 months since cases were first detected in China. Conscious of the many challenges presented in sett...
32,921,283
J Agromedicine
Partnerships as an Avenue to Translate Emerging Disease Ecology of SARS-CoV-2 to Agricultural Groups.
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and associated coronavirus disease 19 (COVID-19) has brought farmers and farmworkers the designation of "essential", while placing them into heightened vulnerability for the disease. Many factors diminish access to education and prevention te...
covid-19;airborne transmission;farmers;farmworkers;healthcare
Journal Article
Liebman, Amy;Roy, Natalie;Seda, Claire;Zuroweste, Ed;Roy, Chad
10.1080/1059924X.2020.1815626
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Partnerships as an Avenue to Translate Emerging Disease Ecology of SARS-CoV-2 to Agricultural Groups. [Abstract]: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and associated coronavirus disease 19 (COVID-19) has brought farmers and farmworkers the designation of "essential", wh...
32,730,358
PLoS One
Prediction model and risk scores of ICU admission and mortality in COVID-19.
This study aimed to develop risk scores based on clinical characteristics at presentation to predict intensive care unit (ICU) admission and mortality in COVID-19 patients. 641 hospitalized patients with laboratory-confirmed COVID-19 were selected from 4997 persons under investigation. We performed a retrospective revi...
Journal Article
Zhao, Zirun;Chen, Anne;Hou, Wei;Graham, James M;Li, Haifang;Richman, Paul S;Thode, Henry C;Singer, Adam J;Duong, Tim Q
10.1371/journal.pone.0236618
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Prediction model and risk scores of ICU admission and mortality in COVID-19. [Abstract]: This study aimed to develop risk scores based on clinical characteristics at presentation to predict intensive care unit (ICU) admission and mortality in COVID-19 patients. 641 hospitalized patients with laboratory-confirm...
32,649,784
Acta Paediatr
Multicentre Spanish study found no incidences of viral transmission in infants born to mothers with COVID-19.
AIM: Our aim was to describe the clinical features of mothers infected with COVID-19 and examine any potential vertical mother to newborn transmission. We also assessed how effective the discharge recommendations were in preventing transmission during the first month of life. METHODS: This multicentre descriptive study...
covid-19;caesarean delivery;breastfeeding;horizontal transmission;newborn infant
Journal Article;Multicenter Study
Marin Gabriel, Miguel A;Cuadrado, Irene;Alvarez Fernandez, Blanca;Gonzalez Carrasco, Ersilia;Alonso Diaz, Clara;Llana Martin, Isabel;Sanchez, Laura;Olivas, Cristina;de Las Heras, Susana;Criado, Enrique
10.1111/apa.15474
[ 0, 1, 0, 0, 1, 0, 0 ]
[Title]: Multicentre Spanish study found no incidences of viral transmission in infants born to mothers with COVID-19. [Abstract]: AIM: Our aim was to describe the clinical features of mothers infected with COVID-19 and examine any potential vertical mother to newborn transmission. We also assessed how effective the di...
32,922,585
Radiol Case Rep
Lung point-of-care (POCUS) ultrasound in a pediatric COVID-19 case.
The World Health Organization categorized coronavirus disease 2019 (COVID-19) as a pandemic due to its high contagion rate and widespread infectivity in February 2020. In the United States, one of the public health concerns is the adequacy of resources to treat infected cases. We describe a case of a previously well, 9...
covid-19;lung ultrasound;pocus
Case Reports
Alilio, Prisca M;Ebeling-Koning, Natalie E;Roth, Kevin R;Desai, Tasha
10.1016/j.radcr.2020.09.007
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Lung point-of-care (POCUS) ultrasound in a pediatric COVID-19 case. [Abstract]: The World Health Organization categorized coronavirus disease 2019 (COVID-19) as a pandemic due to its high contagion rate and widespread infectivity in February 2020. In the United States, one of the public health concerns is the ...
32,562,119
Breast Cancer Res Treat
High-Efficiency Same-Day Approach to Breast Reconstruction During the COVID-19 Crisis.
PURPOSE: As our hospitals conserve and re-allocate resources during the COVID-19 crisis, there is urgent need to determine how best to continue caring for breast cancer patients. During the time window before the COVID-19 critical peak and particularly thereafter, as hospitals are able to resume cancer operations, we a...
breast reconstruction;covid-19;coronavirus;protocol;same-day
Journal Article
Specht, Michelle;Sobti, Nikhil;Rosado, Nikki;Tomczyk, Eleanor;Abbate, Olivia;Ellis, Dan;Liao, Eric C
10.1007/s10549-020-05739-7
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: High-Efficiency Same-Day Approach to Breast Reconstruction During the COVID-19 Crisis. [Abstract]: PURPOSE: As our hospitals conserve and re-allocate resources during the COVID-19 crisis, there is urgent need to determine how best to continue caring for breast cancer patients. During the time window before the...
32,921,712
Acta Biomed
COVID-19: What happened to the healthcare workers of a research and teaching hospital in Milan, Italy?
The paper wants to present the data of infection of the Health Care Workers of a research and teaching hospital in Milan, Italy. The majority (2554, 55.9%) of 4572 HCWs were tested for SARS-CoV-2 and 8.8% were found positive. Most of the tested workers were women, but we found higher relative frequency of positivity fo...
Journal Article
Consonni, Dario;Bordini, Lorenzo;Nava, Carlo;Todaro, Aldo;Lunghi, Giovanna;Lombardi, Andrea;Magioni, Davide;De Palo, Francesco;Guerrieri, Lidia;Gatti, Michele;Serra, Daniele;Polonioli, Marco;Prato, Simone;Muscatello, Antonio;Bandera, Alessandra;Auxilia, Francesco;Castaldi, Silvana
10.23750/abm.v91i3.10361
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19: What happened to the healthcare workers of a research and teaching hospital in Milan, Italy? [Abstract]: The paper wants to present the data of infection of the Health Care Workers of a research and teaching hospital in Milan, Italy. The majority (2554, 55.9%) of 4572 HCWs were tested for SARS-CoV-2 ...
32,340,539
Otolaryngol Head Neck Surg
Otolaryngology Education in the Setting of COVID-19: Current and Future Implications.
The COVID-19 pandemic continues to garner extensive international attention. The pandemic has resulted in significant changes in clinical practice for otolaryngologists in the United States; many changes have been implemented to mitigate risks identified by otolaryngologists in other countries. COVID-19-induced limitat...
consortium;otolaryngology;remote learning;resident education
Journal Article;Review
Comer, Brett T;Gupta, Nikita;Mowry, Sarah E;Malekzadeh, Sonya
10.1177/0194599820923621
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Otolaryngology Education in the Setting of COVID-19: Current and Future Implications. [Abstract]: The COVID-19 pandemic continues to garner extensive international attention. The pandemic has resulted in significant changes in clinical practice for otolaryngologists in the United States; many changes have been...
32,944,387
Cancer Biol Med
COVID-19 in cancer patients: risk, clinical features, and management.
A novel coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread across the world, prompting the World Health Organization to declare the coronavirus disease of 2019 (COVID-19) a public health emergency of international concern. Cancer patients are regarded as a highly vulnerable pop...
anti-viral therapy;covid-19;sars-cov-2;anti-cancer treatment;immunotherapy;inflammation
Journal Article;Research Support, Non-U.S. Gov't;Review
Liu, Cuiwei;Zhao, Yanxia;Okwan-Duodu, Derick;Basho, Reva;Cui, Xiaojiang
10.20892/j.issn.2095-3941.2020.0289
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: COVID-19 in cancer patients: risk, clinical features, and management. [Abstract]: A novel coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread across the world, prompting the World Health Organization to declare the coronavirus disease of 2019 (COVID-19) a public health ...
32,292,802
Virusdisease
Emergence of deadly severe acute respiratory syndrome coronavirus-2 during 2019-2020.
Wuhan, the city in Hubei province in China is in the focus of global community due to the outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), formerly known as 2019-nCoV. The virus emerged in humans from Wuhan seafood market probably via zoonotic trans...
covid-19;china;emergence;global transmission;sars-cov-2;wuhan city
Journal Article;Review
Islam, Arshi;Ahmed, Anwar;Naqvi, Irshad H;Parveen, Shama
10.1007/s13337-020-00575-1
[ 1, 1, 1, 0, 1, 0, 0 ]
[Title]: Emergence of deadly severe acute respiratory syndrome coronavirus-2 during 2019-2020. [Abstract]: Wuhan, the city in Hubei province in China is in the focus of global community due to the outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), for...
32,656,985
Intern Med J
Practical management of inflammatory bowel disease patients during the COVID-19 pandemic: expert commentary from the Gastroenterological Society of Australia Inflammatory Bowel Disease faculty.
The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, has emerged as a public health emergency and challenged healthcare systems globally. In a minority of patients, SARS-CoV-2 manifests with a severe acute respiratory illness and currently there is insufficient data regarding the virulence of COVID-19 in ...
covid-19;crohn disease;sars-cov-2;immunosuppression;inflammatory bowel disease;ulcerative colitis
Journal Article;Review
Aysha, Al-Ani;Rentsch, Clarissa;Prentice, Ralley;Johnson, Doug;Bryant, Robert V;Ward, Mark G;Costello, Samuel P;Lewindon, Peter;Ghaly, Simon;Connor, Susan J;Begun, Jakob;Christensen, Britt
10.1111/imj.14889
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Practical management of inflammatory bowel disease patients during the COVID-19 pandemic: expert commentary from the Gastroenterological Society of Australia Inflammatory Bowel Disease faculty. [Abstract]: The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, has emerged as a public health emergen...
32,695,225
Patient Saf Surg
COVID-19 in the operating room: a review of evolving safety protocols.
Background: The COVID-19 pandemic has already infected more than 3 million people across the world. As the healthworkers man the frontlines, the best practices model is continuously evolving as literature concerning the Coronavirus develops. Methods: A systematic review of the available literature was performed using t...
covid-19;coronavirus;health care workers;orthopaedic surgery;protection;surgeon
Journal Article;Review
Prakash, Lakshmanan;Dhar, Shabir Ahmed;Mushtaq, Muzaffar
10.1186/s13037-020-00254-6
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 in the operating room: a review of evolving safety protocols. [Abstract]: Background: The COVID-19 pandemic has already infected more than 3 million people across the world. As the healthworkers man the frontlines, the best practices model is continuously evolving as literature concerning the Coronavi...
32,497,623
Math Biosci
A data-driven network model for the emerging COVID-19 epidemics in Wuhan, Toronto and Italy.
The ongoing Coronavirus Disease 2019 (COVID-19) pandemic threatens the health of humans and causes great economic losses. Predictive modeling and forecasting the epidemic trends are essential for developing countermeasures to mitigate this pandemic. We develop a network model, where each node represents an individual a...
covid-19;control measures;heterogeneity;mitigation strategies;network model
Journal Article;Research Support, Non-U.S. Gov't
Xue, Ling;Jing, Shuanglin;Miller, Joel C;Sun, Wei;Li, Huafeng;Estrada-Franco, Jose Guillermo;Hyman, James M;Zhu, Huaiping
10.1016/j.mbs.2020.108391
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: A data-driven network model for the emerging COVID-19 epidemics in Wuhan, Toronto and Italy. [Abstract]: The ongoing Coronavirus Disease 2019 (COVID-19) pandemic threatens the health of humans and causes great economic losses. Predictive modeling and forecasting the epidemic trends are essential for developing...
32,600,649
Acta Otorrinolaringol Esp
Strategies for the practice of otolaryngology and head and neck surgery during the monitoring phase of COVID-19.
The appearance of a new coronavirus disease called COVID-19 at the end of 2019 and its pandemic expansion in the world has changed the usual practice of the specialty of Otorhinolaryngology (ENT). After a phase of exponential growth of infections, it has been possible to enter a phase of control of the spread of the di...
covid-19;diagnosis srds-cov-2;diagnostico de sars-cov-2;medidas preventivas en covid-19;preventive measures covid-19;serological covid-19;serologia covid-19
Journal Article;Review
Maza-Solano, Juan Manuel;Plaza-Mayor, Guillermo;Jimenez-Luna, Antonio;Parente-Arias, Pablo;Amor-Dorado, Juan Carlos
10.1016/j.otorri.2020.05.001
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Strategies for the practice of otolaryngology and head and neck surgery during the monitoring phase of COVID-19. [Abstract]: The appearance of a new coronavirus disease called COVID-19 at the end of 2019 and its pandemic expansion in the world has changed the usual practice of the specialty of Otorhinolaryngol...
32,784,125
Curr Opin Virol
Natural killer cell responses to emerging viruses of zoonotic origin.
Emerging viral diseases pose a major threat to public health worldwide. Nearly all emerging viruses, including Ebola, Dengue, Nipah, West Nile, Zika, and coronaviruses (including SARS-Cov2, the causative agent of the current COVID-19 pandemic), have zoonotic origins, indicating that animal-to-human transmission constit...
Journal Article;Research Support, Non-U.S. Gov't;Review
Diaz-Salazar, Carlos;Sun, Joseph C
10.1016/j.coviro.2020.07.003
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Natural killer cell responses to emerging viruses of zoonotic origin. [Abstract]: Emerging viral diseases pose a major threat to public health worldwide. Nearly all emerging viruses, including Ebola, Dengue, Nipah, West Nile, Zika, and coronaviruses (including SARS-Cov2, the causative agent of the current COVI...
32,310,715
Surg Infect (Larchmt)
Surgical Infection Society Guidance for Operative and Peri-Operative Care of Adult Patients Infected by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2).
Background: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-associated viral infection (coronavirus disease 2019, COVID-19) is a virulent, contagious viral pandemic that is affecting populations worldwide. As with any airborne viral respiratory infection, surgical and non-surgical patients may be affected....
covid-19;sars-cov-2;sis;guidelines;pandemic;virus infection
Journal Article;Practice Guideline;Review
Heffernan, Daithi S;Evans, Heather L;Huston, Jared M;Claridge, Jeffrey A;Blake, David P;May, Addison K;Beilman, Greg S;Barie, Philip S;Kaplan, Lewis J
10.1089/sur.2020.101
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Surgical Infection Society Guidance for Operative and Peri-Operative Care of Adult Patients Infected by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). [Abstract]: Background: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-associated viral infection (coronavirus disease 2019, CO...
32,292,847
JACC Basic Transl Sci
The Heart in COVID-19: Primary Target or Secondary Bystander?
In the throes of the current coronavirus disease-2019 (COVID-19) pandemic, interest has burgeoned in the cardiovascular complications of this virulent viral infection. As troponin, a biomarker of cardiac injury, often rises in hospitalized patients, its interpretation and actionability require careful consideration. Fu...
atherosclerosis;cytokines;endothelial cells;inflammation;sepsis;vascular biology
Journal Article
Libby, Peter
10.1016/j.jacbts.2020.04.001
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The Heart in COVID-19: Primary Target or Secondary Bystander? [Abstract]: In the throes of the current coronavirus disease-2019 (COVID-19) pandemic, interest has burgeoned in the cardiovascular complications of this virulent viral infection. As troponin, a biomarker of cardiac injury, often rises in hospitaliz...
32,344,167
Clin Microbiol Infect
Umifenovir treatment is not associated with improved outcomes in patients with coronavirus disease 2019: a retrospective study.
OBJECTIVES: Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Umifenovir (Arbidol(R)) is an antiviral drug being used to treat influenza in Russia and China. This study aimed to investigate the effectiveness and safety of umifenovir for COVID-19. METHODS:...
antiviral intervention;arbidol;corona virus disease 2019;effectiveness;umifenovir
Journal Article
Lian, N;Xie, H;Lin, S;Huang, J;Zhao, J;Lin, Q
10.1016/j.cmi.2020.04.026
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Umifenovir treatment is not associated with improved outcomes in patients with coronavirus disease 2019: a retrospective study. [Abstract]: OBJECTIVES: Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Umifenovir (Arbidol(R)) is an antiviral drug...
32,572,019
Rev Esp Salud Publica
[Digital surveillance tools for contact tracking of infected persons by SARS-CoV-2.]
BACKGROUND: In times of pandemic, case management and tracking people with contact can be differential elements for controlling the spread. The objective of this review was to evaluate the digital tools used to track contacts of people infected with SARS-CoV-2. METHODS: A systematic exploratory review was conducted in ...
communicable disease control;contact tracing;covid-19;epidemiological monitoring;medical informatics applications;public health;spain
Journal Article;Review
Garcia-Iglesias, Juan Jesus;Martin-Pereira, Jorge;Fagundo-Rivera, Javier;Gomez-Salgado, Juan
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [Digital surveillance tools for contact tracking of infected persons by SARS-CoV-2.] [Abstract]: BACKGROUND: In times of pandemic, case management and tracking people with contact can be differential elements for controlling the spread. The objective of this review was to evaluate the digital tools used to tra...
32,437,933
Int J Infect Dis
Viral dynamics in asymptomatic patients with COVID-19.
Data are limited on the viral load, viral shedding patterns, and potential infectivity of asymptomatic patients (APs) with coronavirus disease 2019 (COVID-19). This study included 31 adult patients who were virologically confirmed to have COVID-19 but were asymptomatic on admission. Among these 31 patients, 22 presente...
asymptomatic patients;covid-19;viral load;viral shedding
Journal Article
Zhou, Rui;Li, Furong;Chen, Fengjuan;Liu, Huamin;Zheng, Jiazhen;Lei, Chunliang;Wu, Xianbo
10.1016/j.ijid.2020.05.030
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Viral dynamics in asymptomatic patients with COVID-19. [Abstract]: Data are limited on the viral load, viral shedding patterns, and potential infectivity of asymptomatic patients (APs) with coronavirus disease 2019 (COVID-19). This study included 31 adult patients who were virologically confirmed to have COVID...
32,766,112
Integr Med Res
Evidence map on the contributions of traditional, complementary and integrative medicines for health care in times of COVID-19.
Background: Due to the pandemic, there is a significant interest in the therapeutic resources linked to TCIM to support potentially therapeutic research and intervention in the management of Coronavirus - 19 (COVID-19). At the date of this evidence map s publication, there is no evidence of specific treatments for COVI...
covid-19;complementary therapies;evidence map;integrative medicine;systematic review
Journal Article;Review
Portella, Caio Fabio Schlechta;Ghelman, Ricardo;Abdala, Carmen Veronica Mendes;Schveitzer, Mariana Cabral
10.1016/j.imr.2020.100473
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Evidence map on the contributions of traditional, complementary and integrative medicines for health care in times of COVID-19. [Abstract]: Background: Due to the pandemic, there is a significant interest in the therapeutic resources linked to TCIM to support potentially therapeutic research and intervention i...
32,815,353
Tidsskr Nor Laegeforen
SARS-CoV-2 in children and adolescents in Norway: confirmed infection, hospitalisations and underlying conditions.
BACKGROUND: Children and adolescents are at lower risk of disease caused by SARS-CoV-2. We describe the incidence of confirmed infection and hospitalisation of children and adolescents under the age of 20 in Norway, and specifically among those with underlying conditions. MATERIAL AND METHOD: The Norwegian Directorate ...
Journal Article
Stordal, Ketil;Bakken, Inger Johanne;Greve-Isdahl, Margrethe;Klingenberg, Claus;Helland, Eyvind;Nystad, Wenche;Hjellvik, Vidar;Gulseth, Hanne Lovdal
10.4045/tidsskr.20.0457
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: SARS-CoV-2 in children and adolescents in Norway: confirmed infection, hospitalisations and underlying conditions. [Abstract]: BACKGROUND: Children and adolescents are at lower risk of disease caused by SARS-CoV-2. We describe the incidence of confirmed infection and hospitalisation of children and adolescents...
32,175,421
Ann Transl Med
Early estimation of the case fatality rate of COVID-19 in mainland China: a data-driven analysis.
Background: An ongoing outbreak of pneumonia caused by a novel coronavirus [severe acute respiratory syndrome coronavirus (SARS-CoV)-2], named COVID-19, hit a major city of China, Wuhan in December 2019 and subsequently spread to other provinces/regions of China and overseas. Several studies have been done to estimate ...
2019 novel coronavirus;covid-19;case fatality rate (cfr);severe acute respiratory syndrome coronavirus-2 (sars-cov-2)
Journal Article
Yang, Shu;Cao, Peihua;Du, Peipei;Wu, Ziting;Zhuang, Zian;Yang, Lin;Yu, Xuan;Zhou, Qi;Feng, Xixi;Wang, Xiaohui;Li, Weiguo;Liu, Enmei;Chen, Ju;Chen, Yaolong;He, Daihai
10.21037/atm.2020.02.66
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Early estimation of the case fatality rate of COVID-19 in mainland China: a data-driven analysis. [Abstract]: Background: An ongoing outbreak of pneumonia caused by a novel coronavirus [severe acute respiratory syndrome coronavirus (SARS-CoV)-2], named COVID-19, hit a major city of China, Wuhan in December 201...
33,053,830
Molecules
Docking and QSAR of Aminothioureas at the SARS-CoV-2 S-Protein-Human ACE2 Receptor Interface.
Docking of over 160 aminothiourea derivatives at the SARS-CoV-2 S-protein-human ACE2 receptor interface, whose structure became available recently, has been evaluated for its complex stabilizing potency and subsequently subjected to quantitative structure-activity relationship (QSAR) analysis. The structural variety of...
admet;qsar;sars-cov-2;aminothioureas;docking
Journal Article
Plonka, Wojciech;Paneth, Agata;Paneth, Piotr
10.3390/molecules25204645
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Docking and QSAR of Aminothioureas at the SARS-CoV-2 S-Protein-Human ACE2 Receptor Interface. [Abstract]: Docking of over 160 aminothiourea derivatives at the SARS-CoV-2 S-protein-human ACE2 receptor interface, whose structure became available recently, has been evaluated for its complex stabilizing potency an...
32,997,237
Intern Emerg Med
The association of treatment with hydroxychloroquine and hospital mortality in COVID-19 patients.
This study investigates the association between the treatment with hydroxychloroquine and mortality in patients admitted with COVID-19. Routinely recorded, clinical data, up to the 24th of April 2020, from the 2075 patients with COVID-19, admitted in 17 hospitals in Spain between the 1st of March and the 20th of April ...
covid-19;coronavirus infections;hydroxychloroquine;mortality
Journal Article;Multicenter Study
Ayerbe, Luis;Risco-Risco, Carlos;Ayis, Salma
10.1007/s11739-020-02505-x
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: The association of treatment with hydroxychloroquine and hospital mortality in COVID-19 patients. [Abstract]: This study investigates the association between the treatment with hydroxychloroquine and mortality in patients admitted with COVID-19. Routinely recorded, clinical data, up to the 24th of April 2020, ...
32,883,328
Trials
The COVIRL002 Trial-Tocilizumab for management of severe, non-critical COVID-19 infection: A structured summary of a study protocol for a randomised controlled trial.
OBJECTIVES: Tocilizumab is a humanized monoclonal antibody which targets and inhibits interleukin-6 (IL-6) and has demonstrated efficacy in treating diseases associated with hyper-inflammation. Data are suggestive of tocilizumab as a potential treatment for patients with COVID-19 infection. The aim of this study is to ...
covid-19;immunology;randomised controlled trial;therapeutics;tocilizumab;protocol
Clinical Trial Protocol;Letter
Cotter, Aoife;Wallace, Deborah;McCarthy, Cormac;Feeney, Eoin;O'Neill, Lorraine;Stack, John;McCarthy, Geraldine;Hussain, Rabia;Alvarez Barco, Elena;Doran, Peter;Mallon, Patrick
10.1186/s13063-020-04680-w
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: The COVIRL002 Trial-Tocilizumab for management of severe, non-critical COVID-19 infection: A structured summary of a study protocol for a randomised controlled trial. [Abstract]: OBJECTIVES: Tocilizumab is a humanized monoclonal antibody which targets and inhibits interleukin-6 (IL-6) and has demonstrated effi...
32,892,746
Lipids Health Dis
Low high-density lipoprotein level is correlated with the severity of COVID-19 patients: an observational study.
BACKGROUND: The purpose of the study is to describe the blood lipid levels of patients diagnosed with coronavirus disease 2019 (COVID-19) and to analyze the correlation between blood lipid levels and the prognosis of COVID-19 patients. METHODS: In the clinical retrospective analysis, a total of 228 adults infected with...
adult;covid-19;high-density lipoprotein cholesterol;lipoproteins;prognosis;severe acute respiratory syndrome coronavirus 2
Journal Article;Observational Study
Wang, Guyi;Zhang, Quan;Zhao, Xianmei;Dong, Haiyun;Wu, Chenfang;Wu, Fang;Yu, Bo;Lv, Jianlei;Zhang, Siye;Wu, Guobao;Wu, Shangjie;Wang, Xiaolei;Wu, Ying;Zhong, Yanjun
10.1186/s12944-020-01382-9
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Low high-density lipoprotein level is correlated with the severity of COVID-19 patients: an observational study. [Abstract]: BACKGROUND: The purpose of the study is to describe the blood lipid levels of patients diagnosed with coronavirus disease 2019 (COVID-19) and to analyze the correlation between blood lip...
32,720,298
J Urban Health
A Community Responds to the COVID-19 Pandemic: a Case Study in Protecting the Health and Human Rights of People Who Use Drugs.
Effective responses to a global pandemic require local action. In the face of a pandemic or similar emergencies, communities of people who use drugs face risks that result from their ongoing drug use, reduced ability to secure treatment for drug use and correlated maladies, lack of access to preventive hygiene, and the...
covid-19;harm reduction;homelessness;incarceration;people who use drugs;substance abuse disorders;treatment for opioid use disorders
Journal Article
Heimer, Robert;McNeil, Ryan;Vlahov, David
10.1007/s11524-020-00465-3
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A Community Responds to the COVID-19 Pandemic: a Case Study in Protecting the Health and Human Rights of People Who Use Drugs. [Abstract]: Effective responses to a global pandemic require local action. In the face of a pandemic or similar emergencies, communities of people who use drugs face risks that result ...
32,250,244
Elife
Potential harmful effects of discontinuing ACE-inhibitors and ARBs in COVID-19 patients.
The discovery of angiotensin converting enzyme-2 (ACE-2) as the receptor for SARS- CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) has implicated the renin-angiotensin-aldosterone system in acute respiratory distress syndrome (ARDS) and respiratory failure in patients with coronavirus disease-19 (COVID-19). The...
ace;ace inhibitor;ace inhibitors;ace-2;aceis;arbs;ards;acute respiratory distress syndrome;covid-19;raas;sars;sars-cov-2;angiotensin;angiotensin receptor antagonists;angiotensin receptor blocker;angiotensin-converting enzyme-1;angiotensin-converting enzyme-2;arterial hypertension;cardiovascular;coronavirus;human biolog...
Journal Article
Rossi, Gian Paolo;Sanga, Viola;Barton, Matthias
10.7554/eLife.57278
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Potential harmful effects of discontinuing ACE-inhibitors and ARBs in COVID-19 patients. [Abstract]: The discovery of angiotensin converting enzyme-2 (ACE-2) as the receptor for SARS- CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) has implicated the renin-angiotensin-aldosterone system in acute respir...
32,818,606
Respir Physiol Neurobiol
Chest physiotherapy: An important adjuvant in critically ill mechanically ventilated patients with COVID-19.
In late 2019, an outbreak of a novel human coronavirus causing respiratory disease was identified in Wuhan, China. The virus spread rapidly worldwide, reaching pandemic status. Chest computed tomography scans of patients with coronavirus disease-2019 (COVID-19) have revealed different stages of respiratory involvement,...
covid-19;chest physiotherapy;extubation;mechanical ventilation;sars-cov-2
Journal Article;Research Support, Non-U.S. Gov't;Review
Battaglini, Denise;Robba, Chiara;Caiffa, Salvatore;Ball, Lorenzo;Brunetti, Iole;Loconte, Maurizio;Giacobbe, Daniele Roberto;Vena, Antonio;Patroniti, Nicolo;Bassetti, Matteo;Torres, Antoni;Rocco, Patricia Rm;Pelosi, Paolo
10.1016/j.resp.2020.103529
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Chest physiotherapy: An important adjuvant in critically ill mechanically ventilated patients with COVID-19. [Abstract]: In late 2019, an outbreak of a novel human coronavirus causing respiratory disease was identified in Wuhan, China. The virus spread rapidly worldwide, reaching pandemic status. Chest compute...
32,890,254
J Public Health Manag Pract
COVID-19's Impact on Women: A Stakeholder-Engagement Approach to Increase Public Awareness Through Virtual Town Halls.
Women face unprecedented challenges imposed by the COVID-19 pandemic. Emerging evidence suggests that women are unduly burdened by inequitable access to economic, health, and social resources during the pandemic. For many women, COVID-19 has presented new urgency to challenges and illuminates unique issues long encount...
Journal Article
Allen, Shauntice;Julian, Zoe;Coyne-Beasley, Tamera;Erwin, Paul C;Fletcher, Faith E
10.1097/PHH.0000000000001249
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19's Impact on Women: A Stakeholder-Engagement Approach to Increase Public Awareness Through Virtual Town Halls. [Abstract]: Women face unprecedented challenges imposed by the COVID-19 pandemic. Emerging evidence suggests that women are unduly burdened by inequitable access to economic, health, and socia...
32,233,018
Diabetes Metab Res Rev
Covid-19 and diabetes mellitus: unveiling the interaction of two pandemics.
A novel RNA betacoronavirus causing coronavirus disease 2019 (Covid-19) has now been declared pandemic disease by WHO. Guo et al published the first report of biochemical features in patients with diabetes and the further risk that this disease can determine to the progression of Covid-19. Among different cytokines fou...
covid-19;diabetes;inflammation; il-6
Journal Article
Maddaloni, Ernesto;Buzzetti, Raffaella
10.1002/dmrr.3321
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Covid-19 and diabetes mellitus: unveiling the interaction of two pandemics. [Abstract]: A novel RNA betacoronavirus causing coronavirus disease 2019 (Covid-19) has now been declared pandemic disease by WHO. Guo et al published the first report of biochemical features in patients with diabetes and the further r...
32,531,257
Clin Chim Acta
Lactate dehydrogenase and C-reactive protein as predictors of respiratory failure in CoVID-19 patients.
OBJECTIVE: The dramatic worldwide CoVID-19 infection requires the identification of a reliable and inexpensive tool to quickly discriminate patients with a more unfavorable outcome. METHODS: We performed routine laboratory tests suitable to identify tissue damage and inflammatory status in 123 consecutive CoVID-19 pati...
acute respiratory failure;crp;covid-19;covid-19 pneumonia;italian epidemic;ldh
Journal Article;Observational Study
Poggiali, Erika;Zaino, Domenica;Immovilli, Paolo;Rovero, Luca;Losi, Giulia;Dacrema, Alessandro;Nuccetelli, Marzia;Vadacca, Giovanni Battista;Guidetti, Donata;Vercelli, Andrea;Magnacavallo, Andrea;Bernardini, Sergio;Terracciano, Chiara
10.1016/j.cca.2020.06.012
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Lactate dehydrogenase and C-reactive protein as predictors of respiratory failure in CoVID-19 patients. [Abstract]: OBJECTIVE: The dramatic worldwide CoVID-19 infection requires the identification of a reliable and inexpensive tool to quickly discriminate patients with a more unfavorable outcome. METHODS: We p...
32,947,412
Cornea
Eye Banking: One Cornea for Multiple Recipients.
PURPOSE: Corneal transplantation is the most frequently performed transplant procedure. In much of the world, the demand for donor tissue heavily outstrips supply. With developments within lamellar corneal graft surgery, the use of split corneal donor tissue to increase donor tissue supply seems a pragmatic solution to...
Journal Article;Review
Gadhvi, Kunal A;Coco, Giulia;Pagano, Luca;Kaye, Stephen B;Ferrari, Stefano;Levis, Hannah J;Parekh, Mohit;Romano, Vito
10.1097/ICO.0000000000002476
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Eye Banking: One Cornea for Multiple Recipients. [Abstract]: PURPOSE: Corneal transplantation is the most frequently performed transplant procedure. In much of the world, the demand for donor tissue heavily outstrips supply. With developments within lamellar corneal graft surgery, the use of split corneal dono...
32,586,891
BMJ Glob Health
Voices from the frontline: findings from a thematic analysis of a rapid online global survey of maternal and newborn health professionals facing the COVID-19 pandemic.
INTRODUCTION: The COVID-19 pandemic has substantially impacted maternity care provision worldwide. Studies based on modelling estimated large indirect effects of the pandemic on services and health outcomes. The objective of this study was to prospectively document experiences of frontline maternal and newborn healthca...
child health;cross-sectional survey;health services research;health systems;maternal health
Journal Article
Semaan, Aline;Audet, Constance;Huysmans, Elise;Afolabi, Bosede;Assarag, Bouchra;Banke-Thomas, Aduragbemi;Blencowe, Hannah;Caluwaerts, Severine;Campbell, Oona Maeve Renee;Cavallaro, Francesca L;Chavane, Leonardo;Day, Louise Tina;Delamou, Alexandre;Delvaux, Therese;Graham, Wendy Jane;Gon, Giorgia;Kascak, Peter;Matsui, Mi...
10.1136/bmjgh-2020-002967
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Voices from the frontline: findings from a thematic analysis of a rapid online global survey of maternal and newborn health professionals facing the COVID-19 pandemic. [Abstract]: INTRODUCTION: The COVID-19 pandemic has substantially impacted maternity care provision worldwide. Studies based on modelling estim...
32,812,619
Photochem Photobiol Sci
Spectrum of virucidal activity from ultraviolet to infrared radiation.
The COVID-19 pandemic has sparked a demand for safe and highly effective decontamination techniques for both personal protective equipment (PPE) and hospital and operating rooms. The gradual lifting of lockdown restrictions warrants the expansion of these measures into the outpatient arena. Ultraviolet C (UVC) radiatio...
Journal Article
Horton, Luke;Torres, Angeli Eloise;Narla, Shanthi;Lyons, Alexis B;Kohli, Indermeet;Gelfand, Joel M;Ozog, David M;Hamzavi, Iltefat H;Lim, Henry W
10.1039/d0pp00221f
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Spectrum of virucidal activity from ultraviolet to infrared radiation. [Abstract]: The COVID-19 pandemic has sparked a demand for safe and highly effective decontamination techniques for both personal protective equipment (PPE) and hospital and operating rooms. The gradual lifting of lockdown restrictions warr...
32,674,190
Pneumologie
[48-Year-Old Triathlete with Severe COVID-19 Pneumonia: Successful and Safe Treatment with Oxygen and CPAP].
We present the case of a 48-year old man, a triathlet, with severe COVID-19 and extensive bilateral pneumonia. On day 7 since onset of symptoms, the patient had fever, cough, rheumatic pain, dyspnea as well as severe hypoxemic respiratory failure (PaO2 49,9 mmHg, PaCO2 35,7 mmHg, Horovitz-Index 130). CT of the lung sho...
Journal Article
Stais, P;Salloum, O;Kuhle, D;Fisteag, S;Kambartel, K;Veelken, D;Ewig, S;Voshaar, T
10.1055/a-1200-3336
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: [48-Year-Old Triathlete with Severe COVID-19 Pneumonia: Successful and Safe Treatment with Oxygen and CPAP]. [Abstract]: We present the case of a 48-year old man, a triathlet, with severe COVID-19 and extensive bilateral pneumonia. On day 7 since onset of symptoms, the patient had fever, cough, rheumatic pain,...
32,774,271
Case Rep Oncol
Weather the Cytokine Storm: A Report of Successful Management of a Colon Cancer Survivor and a Critically Ill Patient with COVID-19.
Patients with novel corona virus infection (COVID-19) can develop acute respiratory failure secondary to acute respiratory distress syndrome. Cytokine storm is suggested as one of underlying mechanisms for the rapid clinical decline. Immunocompromised patients and cancer patients are at particular risk for poor outcome...
covid-19;cancer;cytokine;tocilizumab;virus
Case Reports
Khalid, Mansoor;Dernaika, Tarek;Jacob, Lirin;Annamaraju, Pavan;Guddati, Achuta K
10.1159/000509507
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Weather the Cytokine Storm: A Report of Successful Management of a Colon Cancer Survivor and a Critically Ill Patient with COVID-19. [Abstract]: Patients with novel corona virus infection (COVID-19) can develop acute respiratory failure secondary to acute respiratory distress syndrome. Cytokine storm is sugges...
33,025,724
Colorectal Dis
A worldwide survey on proctological practice during COVID-19 lockdown (ProctoLock 2020): a cross-sectional analysis.
AIM: Proctology is one of the surgical specialties that has suffered the most during COVID-19 pandemic. Using a cross-sectional non-incentivised World Wide Web survey, we aimed to snapshot the current status of proctological practice in six world regions. METHOD: Surgeons affiliated to renowned scientific societies wit...
Journal Article
Gallo, Gaetano;Sturiale, Alessandro;De Simone, Veronica;Di Tanna, Gian Luca;Giani, Iacopo;Grossi, Ugo
10.1111/codi.15394
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A worldwide survey on proctological practice during COVID-19 lockdown (ProctoLock 2020): a cross-sectional analysis. [Abstract]: AIM: Proctology is one of the surgical specialties that has suffered the most during COVID-19 pandemic. Using a cross-sectional non-incentivised World Wide Web survey, we aimed to sn...
32,426,019
Int J Surg
Emergency and essential surgical healthcare services during COVID-19 in low- and middle-income countries: A perspective.
The COVID-19 pandemic resulted in significant changes in health care systems worldwide, with low- and middle-income countries (LMIC) sustaining important repercussions. Specifically, alongside cancellation and postponements of non-essential surgical services, emergency and essential surgical care delivery may become af...
covid-19;coronavirus;global health;global surgery
Journal Article
Ma, Xiya;Vervoort, Dominique;Reddy, Che L;Park, Kee B;Makasa, Emmanuel
10.1016/j.ijsu.2020.05.037
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Emergency and essential surgical healthcare services during COVID-19 in low- and middle-income countries: A perspective. [Abstract]: The COVID-19 pandemic resulted in significant changes in health care systems worldwide, with low- and middle-income countries (LMIC) sustaining important repercussions. Specifica...
32,751,106
Int J Mol Sci
A Rapid, Simple, Inexpensive, and Mobile Colorimetric Assay COVID-19-LAMP for Mass On-Site Screening of COVID-19.
To control the COVID-19 pandemic and prevent its resurgence in areas preparing for a return of economic activities, a method for a rapid, simple, and inexpensive point-of-care diagnosis and mass screening is urgently needed. We developed and evaluated a one-step colorimetric reverse-transcriptional loop-mediated isothe...
covid-19;rt-lamp;sars-cov-2;diagnosis;mass screening;mobile diagnostic;on-site screening
Journal Article
Chow, Franklin Wang-Ngai;Chan, Tony Tat-Yin;Tam, Anthony Raymond;Zhao, Suhui;Yao, Weiming;Fung, Joshua;Cheng, Flora Ka-Kei;Lo, George Chi-Shing;Chu, Stella;Aw-Yong, Kam Leng;Tang, James Yat-Man;Tsang, Chi-Ching;Luk, Hayes Kam-Hei;Wong, Antonio Cheuk-Pui;Li, Kenneth Sze-Ming;Zhu, Longchao;He, Zirong;Tam, Emily Wan Ting;...
10.3390/ijms21155380
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: A Rapid, Simple, Inexpensive, and Mobile Colorimetric Assay COVID-19-LAMP for Mass On-Site Screening of COVID-19. [Abstract]: To control the COVID-19 pandemic and prevent its resurgence in areas preparing for a return of economic activities, a method for a rapid, simple, and inexpensive point-of-care diagnosis...
32,761,981
Eur J Neurol
Impact of COVID-19 outbreak in reperfusion therapies of acute ischaemic stroke in northwest Spain.
BACKGROUND AND PURPOSE: Spain has been one of the countries more heavily stricken by SARS-CoV-2, which has had huge implications for stroke care. The aim was to analyse the impact of the COVID-19 epidemic outbreak on reperfusion therapies for acute ischaemic stroke in the northwest of Spain. METHODS: This was a Spanish...
covid-19;spain;acute stroke therapy;cerebral infarction;ischaemic stroke;thrombectomy;thrombolysis
Journal Article;Multicenter Study;Observational Study
Tejada Meza, H;Lambea Gil, A;Sancho Saldana, A;Martinez-Zabaleta, M;Garmendia Lopetegui, E;Lopez-Cancio Martinez, E;Castanon Apilanez, M;Herrera Isasi, M;Marta Enguita, J;Gomez-Vicente, B;Arenillas, J F;Arenaza Basterrechea, N;Timiraos Fernandez, J J;Sanchez Herrero, J;Macineiras Montero, J L;Castellanos Rodrigo, M;Fer...
10.1111/ene.14467
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of COVID-19 outbreak in reperfusion therapies of acute ischaemic stroke in northwest Spain. [Abstract]: BACKGROUND AND PURPOSE: Spain has been one of the countries more heavily stricken by SARS-CoV-2, which has had huge implications for stroke care. The aim was to analyse the impact of the COVID-19 epid...
32,892,275
Ann Hematol
Ixazomib-based frontline therapy in patients with newly diagnosed multiple myeloma in real-life practice showed comparable efficacy and safety profile with those reported in clinical trial: a multi-center study.
The induction therapy containing ixazomib, an oral proteasome inhibitor, has shown favorable efficacy and safety in clinical trials, but its experience in real-life remains limited. In routine practice, few patients received ixazomib-based induction therapy due to reasons including (1) patients' preference on oral regi...
frontline;ixazomib;myeloma;real-world
Clinical Trial, Phase I;Clinical Trial, Phase II;Journal Article;Multicenter Study;Observational Study
Li, Jing;Bao, Li;Xia, Zhongjun;Wang, Sili;Zhou, Xin;Ding, Kaiyang;Zhang, Wenhao;Yang, Wei;Li, Bingzong;Fu, Chengcheng;Chen, Bing;Hua, Luoming;Wang, Liang;Luo, Jun;Yang, Yang;Xu, Tianhong;Wang, Weida;Huang, Yun;Wu, Guolin;Liu, Peng
10.1007/s00277-020-04234-9
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Ixazomib-based frontline therapy in patients with newly diagnosed multiple myeloma in real-life practice showed comparable efficacy and safety profile with those reported in clinical trial: a multi-center study. [Abstract]: The induction therapy containing ixazomib, an oral proteasome inhibitor, has shown favo...
32,838,146
SN Compr Clin Med
Treatment-Refractory Headache in the Setting of COVID-19 Pneumonia: Migraine or Meningoencephalitis? Case Report.
The coronavirus responsible for the COVID-19 pandemic, SARS-2-CoV, most commonly involves the respiratory tract; however, more severe cases have been found to have multi-organ involvement, including the central nervous system. Headache has been documented as a presenting symptom of COVID-19, which may prompt neurology ...
covid-19;coronavirus;headache;meningitis;meningoencephalitis;migraine
Journal Article
Arca, Karissa N;Starling, Amaal J
10.1007/s42399-020-00369-y
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Treatment-Refractory Headache in the Setting of COVID-19 Pneumonia: Migraine or Meningoencephalitis? Case Report. [Abstract]: The coronavirus responsible for the COVID-19 pandemic, SARS-2-CoV, most commonly involves the respiratory tract; however, more severe cases have been found to have multi-organ involveme...
32,380,708
J Clin Med
Estimation of Unreported Novel Coronavirus (SARS-CoV-2) Infections from Reported Deaths: A Susceptible-Exposed-Infectious-Recovered-Dead Model.
In the midst of the novel coronavirus (SARS-CoV-2) epidemic, examining reported case data could lead to biased speculations and conclusions. Indeed, estimation of unreported infections is crucial for a better understanding of the current emergency in China and in other countries. In this study, we aimed to estimate the...
covid-19;epidemic model;epidemiology;novel coronavirus
Journal Article
Maugeri, Andrea;Barchitta, Martina;Battiato, Sebastiano;Agodi, Antonella
10.3390/jcm9051350
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Estimation of Unreported Novel Coronavirus (SARS-CoV-2) Infections from Reported Deaths: A Susceptible-Exposed-Infectious-Recovered-Dead Model. [Abstract]: In the midst of the novel coronavirus (SARS-CoV-2) epidemic, examining reported case data could lead to biased speculations and conclusions. Indeed, estima...
32,405,117
Antiviral Res
Identification of SARS-CoV RBD-targeting monoclonal antibodies with cross-reactive or neutralizing activity against SARS-CoV-2.
SARS-CoV-2-caused COVID-19 cases are growing globally, calling for developing effective therapeutics to control the current pandemic. SARS-CoV-2 and SARS-CoV recognize angiotensin-converting enzyme 2 (ACE2) receptor via the receptor-binding domain (RBD). Here, we identified six SARS-CoV RBD-specific neutralizing monocl...
covid-19;cross-neutralization;neutralizing monoclonal antibodies;receptor-binding domain;sars-cov;sars-cov-2
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Tai, Wanbo;Zhang, Xiujuan;He, Yuxian;Jiang, Shibo;Du, Lanying
10.1016/j.antiviral.2020.104820
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Identification of SARS-CoV RBD-targeting monoclonal antibodies with cross-reactive or neutralizing activity against SARS-CoV-2. [Abstract]: SARS-CoV-2-caused COVID-19 cases are growing globally, calling for developing effective therapeutics to control the current pandemic. SARS-CoV-2 and SARS-CoV recognize ang...
32,656,309
Virusdisease
Relevance of SARS-CoV-2 in food safety and food hygiene: potential preventive measures, suggestions and nanotechnological approaches.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is easily transmitted from person to person, which has fueled the ongoing pandemic. Governments in different countries have taken drastic actions such as complete lockdown. However, little attention has been paid to food safety and its potential linkage with ...
covid-19;food hygiene;food safety;foodborne viruses;nanotechnology;sars-cov-2
Journal Article;Review
Ceylan, Zafer;Meral, Raciye;Cetinkaya, Turgay
10.1007/s13337-020-00611-0
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Relevance of SARS-CoV-2 in food safety and food hygiene: potential preventive measures, suggestions and nanotechnological approaches. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is easily transmitted from person to person, which has fueled the ongoing pandemic. Governments in diffe...
32,888,638
Heart Fail Clin
Innovation in Ambulatory Care of Heart Failure in the Era of Coronavirus Disease 2019.
Despite steady progress over the past 3 decades in advancing drug and device therapies to reduce morbidity and mortality in heart failure with reduced ejection fraction, large registries of usual care demonstrate incomplete use of these evidence-based therapies in clinical practice. Potential strategies to improve guid...
ambulatory;covid-19;care optimization;guideline-directed medical therapy;heart failure
Journal Article;Review
Leiva, Orly;Bhatt, Ankeet S;Vaduganathan, Muthiah
10.1016/j.hfc.2020.06.004
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Innovation in Ambulatory Care of Heart Failure in the Era of Coronavirus Disease 2019. [Abstract]: Despite steady progress over the past 3 decades in advancing drug and device therapies to reduce morbidity and mortality in heart failure with reduced ejection fraction, large registries of usual care demonstrate...
32,676,882
J Thromb Thrombolysis
How haemophilia A impacts severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) treatment: a case report.
The typical symptoms of COVID-19 mimic those of the common season flu. In addition, several changes in the coagulation processes have been observed. To date, it's not fully clear how COVID-19 may affect patients with hereditary bleeding disorders. Anticoagulation in patients with haemophilia is still debated, but in th...
bleeding disorders;covid-19;coagulation;coronavirus;haemophilia a;sars-cov-2
Case Reports
Zanon, Ezio;Pasca, Samantha;Campello, Elena;Spiezia, Luca;Vettor, Roberto;Simioni, Paolo
10.1007/s11239-020-02227-z
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: How haemophilia A impacts severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) treatment: a case report. [Abstract]: The typical symptoms of COVID-19 mimic those of the common season flu. In addition, several changes in the coagulation processes have been observed. To date, it's not fully clear how COV...
32,591,286
Radiography (Lond)
Reporting radiographers' interpretation and use of the British Society of Thoracic Imaging's coding system when reporting COVID-19 chest x-rays.
INTRODUCTION: The United Kingdom (UK) has experienced one of the worst initial waves of the COVID-19 pandemic. Clinical signs help guide initial diagnosis, though definitive diagnosis is made using the laboratory technique reverse transcription polymerase chain reaction (RT-PCR). The chest x-ray (CXR) is used as the pr...
advanced practice;bsti;covid-19;cxr;reporting radiographers
Journal Article
Stevens, Barry J
10.1016/j.radi.2020.06.010
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Reporting radiographers' interpretation and use of the British Society of Thoracic Imaging's coding system when reporting COVID-19 chest x-rays. [Abstract]: INTRODUCTION: The United Kingdom (UK) has experienced one of the worst initial waves of the COVID-19 pandemic. Clinical signs help guide initial diagnosis...
32,820,884
Pol Arch Intern Med
Neurological symptoms as a clinical manifestation of COVID-19: implications for internists.
Many experimental and clinical studies have proven that the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has tropism to the nervous system. The infection of the nervous system by SARS-CoV-2 can occur via the nasal route through trans-synaptic pathways. Coronaviruses can infect neurons and glial cell...
Journal Article;Review
Adamczyk-Sowa, Monika;Niedziela, Natalia;Kubicka-Baczyk, Katarzyna;Wierzbicki, Krzysztof;Jaroszewicz, Jerzy;Sowa, Pawel
10.20452/pamw.15575
[ 0, 1, 1, 1, 0, 0, 0 ]
[Title]: Neurological symptoms as a clinical manifestation of COVID-19: implications for internists. [Abstract]: Many experimental and clinical studies have proven that the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has tropism to the nervous system. The infection of the nervous system by SARS-CoV...
32,769,822
Shock
Fibrinolysis Shutdown and Thrombosis in A COVID-19 ICU.
The coronavirus disease (COVID-19) pandemic has threatened millions of lives worldwide with severe systemic inflammation, organ dysfunction, and thromboembolic disease. Within our institution, many critically ill COVID-19 positive patients suffered major thrombotic events, prompting our clinicians to evaluate hypercoag...
Journal Article;Research Support, N.I.H., Extramural
Creel-Bulos, Christina;Auld, Sara C;Caridi-Scheible, Mark;Barker, Nicholas;Friend, Sarah;Gaddh, Manila;Kempton, Christine L;Maier, Cheryl;Nahab, Fadi;Sniecinski, Roman
10.1097/SHK.0000000000001635
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Fibrinolysis Shutdown and Thrombosis in A COVID-19 ICU. [Abstract]: The coronavirus disease (COVID-19) pandemic has threatened millions of lives worldwide with severe systemic inflammation, organ dysfunction, and thromboembolic disease. Within our institution, many critically ill COVID-19 positive patients suf...
32,426,111
Pulm Circ
Care of patients with pulmonary arterial hypertension during the coronavirus (COVID-19) pandemic.
The COVID-19 pandemic presents many unique challenges when caring for patients with pulmonary hypertension. The COVID-19 pandemic has altered routine standard of care practice and the acute management particularly for those patients with pulmonary arterial hypertension, where pulmonary arterial hypertension-specific tr...
clinical trials;mechanical ventilation;prostacyclin;pulmonary hypertension;right heart failure;therapeutics
Journal Article
Ryan, John J;Melendres-Groves, Lana;Zamanian, Roham T;Oudiz, Ronald J;Chakinala, Murali;Rosenzweig, Erika B;Gomberg-Maitland, Mardi
10.1177/2045894020920153
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Care of patients with pulmonary arterial hypertension during the coronavirus (COVID-19) pandemic. [Abstract]: The COVID-19 pandemic presents many unique challenges when caring for patients with pulmonary hypertension. The COVID-19 pandemic has altered routine standard of care practice and the acute management ...
32,800,857
Int J Infect Dis
The costs of an expanded screening criteria for COVID-19: A modelling study.
OBJECTIVES: Nosocomial infection is an ongoing concern in the COVID-19 outbreak. The effective screening of suspected cases in the healthcare setting is therefore necessary, enabling the early identification and prompt isolation of cases for epidemic containment. We aimed to assess the cost and health outcomes of an ex...
covid-19;extended screening criteria;nosocomial infection;sars-cov-2
Journal Article
Lim, Jue Tao;Dickens, Borame L;Cook, Alex R;Khoo, Ai Leng;Dan, Yock Young;Fisher, Dale Andrew;Tambyah, Paul Anantharajah;Chai, Louis Yi Ann
10.1016/j.ijid.2020.08.025
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The costs of an expanded screening criteria for COVID-19: A modelling study. [Abstract]: OBJECTIVES: Nosocomial infection is an ongoing concern in the COVID-19 outbreak. The effective screening of suspected cases in the healthcare setting is therefore necessary, enabling the early identification and prompt iso...
32,785,928
Oncology (Williston Park)
Challenges of Treating a Patient With Advanced Prostate Cancer During the COVID-19 Pandemic.
A 78-year-old man had a medical history of hypertension, atrial fibrillation, chronic kidney disease, and metastatic castration-resistant prostate cancer (CRPC). He had progressed to first-line therapy for CRPC with abiraterone plus androgen-deprivation therapy (ADT) and as second-line therapy he was being treated with...
Case Reports
Carril-Ajuria, Lucil;Remolina-Bonilla, Yuly A;Carretero-Gonzalez, Alberto;Martin-Soberon, Maricruz;Castellano, Daniel;Bourlon, Christianne;de Velasco, Guillermo;Bourlon, Maria T
10.46883/ONC.2020.3408.0317
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Challenges of Treating a Patient With Advanced Prostate Cancer During the COVID-19 Pandemic. [Abstract]: A 78-year-old man had a medical history of hypertension, atrial fibrillation, chronic kidney disease, and metastatic castration-resistant prostate cancer (CRPC). He had progressed to first-line therapy for ...
32,838,011
Int J Pediatr Adolesc Med
Approach to childhood asthma in the era of COVID-19: The official statement endorsed by the Saudi Pediatric Pulmonology Association (SPPA).
Coronaviruses are a large family of viruses that infect humans, which may result in mild symptoms similar to those of the common cold. COVID-19 is most recent subtype similar or even worse than the two previous pandemic strains which were the severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East ...
asthma;covid-19;covid-19, coronavirus. novel coronavirus-2019;mdi, metered dose inhaler;ppe, personal protective equipment;sina, the saudi initiative for asthma;sppa, saudi pediatric pulmonology association;sts, the saudi thoracic society;saudi pediatric pulmonology association (sppa);vhc, valved holding chamber;wap, w...
Journal Article
Al-Shamrani, Abdullah;Al-Harbi, Adel S;Alhaider, S A;Alharbi, Saleh;Al-Harbi, Nasser S;Alanazi, Alnashmi;Al Ahmadi, Turki S
10.1016/j.ijpam.2020.07.001
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Approach to childhood asthma in the era of COVID-19: The official statement endorsed by the Saudi Pediatric Pulmonology Association (SPPA). [Abstract]: Coronaviruses are a large family of viruses that infect humans, which may result in mild symptoms similar to those of the common cold. COVID-19 is most recent ...
32,827,462
Am J Pathol
Universal Precautions Provide Appropriate Protection during Autopsies of Patients with Infectious Diseases.
The current coronavirus disease 2019 (COVID-19) pandemic has raised concerns about the safety of laboratory personnel who handle tissue samples that harbor pathogens, including those performing autopsies. While pathologists have performed autopsies on infected decedents for centuries, universal precaution protocols for...
Journal Article;Research Support, N.I.H., Extramural;Review
Kritselis, Michael;Remick, Daniel G
10.1016/j.ajpath.2020.08.005
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Universal Precautions Provide Appropriate Protection during Autopsies of Patients with Infectious Diseases. [Abstract]: The current coronavirus disease 2019 (COVID-19) pandemic has raised concerns about the safety of laboratory personnel who handle tissue samples that harbor pathogens, including those performi...
32,744,709
Eur Rev Med Pharmacol Sci
From SARS-CoV to SARS-CoV2: a potential guide to better understanding of pathophysiology of the disease and potential therapeutic modality.
Currently, the outbreak and spread of coronavirus disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), are increasing worldwide. Furthermore, it has been considered as a major challenge, which threatens human beings and affects all aspects of their life. Understanding the cell...
Journal Article;Research Support, Non-U.S. Gov't;Review
Abbasi Pashaki, P;Habibi Roudkenar, M;Rahim, F;Ebrahimi, A
10.26355/eurrev_202007_22286
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: From SARS-CoV to SARS-CoV2: a potential guide to better understanding of pathophysiology of the disease and potential therapeutic modality. [Abstract]: Currently, the outbreak and spread of coronavirus disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), are increasin...
32,734,298
Phys Ther
Promoting Physical Activity via Telehealth in People With Parkinson Disease: The Path Forward After the COVID-19 Pandemic?
OBJECTIVE: There is mounting evidence in support of exercise and physical activity as a first-line approach to managing symptoms and potentially altering disease progression in people with Parkinson disease (PD). For many patients, a critical gap is the need for expert guidance to overcome barriers, set realistic goals...
Journal Article;Research Support, Non-U.S. Gov't
Quinn, Lori;Macpherson, Chelsea;Long, Katrina;Shah, Hiral
10.1093/ptj/pzaa128
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Promoting Physical Activity via Telehealth in People With Parkinson Disease: The Path Forward After the COVID-19 Pandemic? [Abstract]: OBJECTIVE: There is mounting evidence in support of exercise and physical activity as a first-line approach to managing symptoms and potentially altering disease progression in...
32,936,281
JAMA Surg
Restructuring of a General Surgery Residency Program in an Epicenter of the Coronavirus Disease 2019 Pandemic: Lessons From New York City.
On March 1, 2020, the first case of coronavirus disease 2019 (COVID-19) was confirmed in New York, New York. Since then, the city has emerged as an epicenter for the ongoing pandemic in the US. To meet the anticipated demand caused by the predicted surge of patients with COVID-19, the Department of Surgery at NewYork-P...
Journal Article;Review
Juprasert, Jackly M;Gray, Katherine D;Moore, Maureen D;Obeid, Lama;Peters, Alexander W;Fehling, David;Fahey, Thomas J 3rd;Yeo, Heather L
10.1001/jamasurg.2020.3107
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Restructuring of a General Surgery Residency Program in an Epicenter of the Coronavirus Disease 2019 Pandemic: Lessons From New York City. [Abstract]: On March 1, 2020, the first case of coronavirus disease 2019 (COVID-19) was confirmed in New York, New York. Since then, the city has emerged as an epicenter fo...
32,446,167
J Clin Virol
Coronavirus disease 2019 in children: Characteristics, antimicrobial treatment, and outcomes.
BACKGROUND: At present, coronavirus disease 2019 (COVID-19) has spread in many countries. We conducted this study to help pediatricians understand the conditions of COVID-19 in children. METHODS: We retrospectively summarized the characteristics, treatment and outcomes of pediatric cases in Wuhan Children's Hospital wh...
characteristics;coronavirus disease 2019;outcomes;pediatric;treatment
Journal Article
Peng, Hui;Gao, Ping;Xu, Qiong;Liu, Maochang;Peng, Jing;Wang, Yang;Xu, Hua
10.1016/j.jcv.2020.104425
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Coronavirus disease 2019 in children: Characteristics, antimicrobial treatment, and outcomes. [Abstract]: BACKGROUND: At present, coronavirus disease 2019 (COVID-19) has spread in many countries. We conducted this study to help pediatricians understand the conditions of COVID-19 in children. METHODS: We retros...
32,708,858
Medicina (Kaunas)
A Patient with Cryoglobulinemic Membranoproliferative GN (MPGN) Who Survived COVID-19 Disease: Case Presentation and Current Data of COVID-19 Infection in Dialysis and Transplanted Patients in Greece.
The evolving pandemic of Coronavirus Disease 2019 has posed a substantial health risk worldwide. However, there is a paucity of data regarding the clinical course and the therapeutic management of patients with chronic kidney disease and COVID-19 infection. To date, most evidence has come from renal transplantation, wi...
covid-19;renal replacement therapy (rrt);glomerulonephritis;immunosuppression;pneumonia;transplantation
Case Reports
Marinaki, Smaragdi;Tsiakas, Stathis;Skalioti, Chrysanthi;Lourida, Panayiota;Argyraki, Aikaterini;Grigorakos, Konstantinos;Boletis, Ioannis
10.3390/medicina56070355
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: A Patient with Cryoglobulinemic Membranoproliferative GN (MPGN) Who Survived COVID-19 Disease: Case Presentation and Current Data of COVID-19 Infection in Dialysis and Transplanted Patients in Greece. [Abstract]: The evolving pandemic of Coronavirus Disease 2019 has posed a substantial health risk worldwide. H...
32,609,044
Int J Audiol
Pure-tone audiometry without bone-conduction thresholds: using the digits-in-noise test to detect conductive hearing loss.
Objective: COVID-19 has been prohibitive to traditional audiological services. No- or low-touch audiological assessment outside a sound-booth precludes test batteries including bone conduction audiometry. This study investigated whether conductive hearing loss (CHL) can be differentiated from sensorineural hearing loss...
covid-19;audiometry;coronavirus;digits-in-noise;speech recognition threshold;speech-in-noise
Journal Article;Research Support, N.I.H., Extramural
De Sousa, Karina C;Smits, Cas;Moore, David R;Myburgh, Hermanus Carel;Swanepoel, De Wet
10.1080/14992027.2020.1783585
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Pure-tone audiometry without bone-conduction thresholds: using the digits-in-noise test to detect conductive hearing loss. [Abstract]: Objective: COVID-19 has been prohibitive to traditional audiological services. No- or low-touch audiological assessment outside a sound-booth precludes test batteries including...
32,954,015
Wellcome Open Res
Anonymised and aggregated crowd level mobility data from mobile phones suggests that initial compliance with COVID-19 social distancing interventions was high and geographically consistent across the UK.
Background: Since early March 2020, the COVID-19 epidemic across the United Kingdom has led to a range of social distancing policies, which have resulted in reduced mobility across different regions. Crowd level data on mobile phone usage can be used as a proxy for actual population mobility patterns and provide a way ...
covid-19;mobile phone;mobility;sars-cov-2;united kingdom
Journal Article
Jeffrey, Benjamin;Walters, Caroline E;Ainslie, Kylie E C;Eales, Oliver;Ciavarella, Constanze;Bhatia, Sangeeta;Hayes, Sarah;Baguelin, Marc;Boonyasiri, Adhiratha;Brazeau, Nicholas F;Cuomo-Dannenburg, Gina;FitzJohn, Richard G;Gaythorpe, Katy;Green, William;Imai, Natsuko;Mellan, Thomas A;Mishra, Swapnil;Nouvellet, Pierre;U...
10.12688/wellcomeopenres.15997.1
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Anonymised and aggregated crowd level mobility data from mobile phones suggests that initial compliance with COVID-19 social distancing interventions was high and geographically consistent across the UK. [Abstract]: Background: Since early March 2020, the COVID-19 epidemic across the United Kingdom has led to ...
32,924,007
Clin Infect Pract
Cold agglutinin syndrome as a complication of Covid-19 in two cases.
Background: Cold agglutinins are autoantibodies against RBC antigens, leading to hemolysis at less-than-physiological temperatures through complement fixation. Production can be triggered by infections, resulting in secondary cold agglutinin syndrome (CAS). This syndrome has been classically described in the setting of...
cold agglutinins;covid-19;hemolytic anemia
Case Reports
Jensen, Christopher E;Wilson, Samuel;Thombare, Aparna;Weiss, Susan;Ma, Alice
10.1016/j.clinpr.2020.100041
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Cold agglutinin syndrome as a complication of Covid-19 in two cases. [Abstract]: Background: Cold agglutinins are autoantibodies against RBC antigens, leading to hemolysis at less-than-physiological temperatures through complement fixation. Production can be triggered by infections, resulting in secondary cold...
33,037,824
J Gastroenterol Hepatol
Benefits of phone consultation for endoscopy-related clinics in the COVID-19 pandemic.
BACKGROUND AND AIM: During COVID-19 outbreak, restrictions to in-person consultations were introduced with a rise in telehealth. An indirect benefit of telehealth could be better attendance. This study aimed to assess "failure-to-attend" (FTA) rate and satisfaction for two endoscopy-related compulsory telehealth clinic...
covid-19;endoscopy;outpatient clinic;telehealth
Journal Article
Zorron Cheng Tao Pu, Leonardo;Singh, Gurpreet;Rajadurai, Anton;Terbah, Ryma;De Silva, Rahil;Vaughan, Rhys;Efthymiou, Marios;Chandran, Sujievvan
10.1111/jgh.15292
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Benefits of phone consultation for endoscopy-related clinics in the COVID-19 pandemic. [Abstract]: BACKGROUND AND AIM: During COVID-19 outbreak, restrictions to in-person consultations were introduced with a rise in telehealth. An indirect benefit of telehealth could be better attendance. This study aimed to a...
33,020,999
Diabet Med
Increased paediatric presentations of severe diabetic ketoacidosis in an Australian tertiary centre during the COVID-19 pandemic.
AIMS: To determine if the frequency of severe diabetic ketoacidosis at presentation of new-onset type 1 diabetes to an Australian tertiary centre increased during the initial period of restrictions resulting from the COVID-19 pandemic (March to May 2020). METHODS: Data were collected on presentations of newly diagnosed...
Journal Article
Lawrence, C;Seckold, R;Smart, C;King, B R;Howley, P;Feltrin, R;Smith, T A;Roy, R;Lopez, P
10.1111/dme.14417
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Increased paediatric presentations of severe diabetic ketoacidosis in an Australian tertiary centre during the COVID-19 pandemic. [Abstract]: AIMS: To determine if the frequency of severe diabetic ketoacidosis at presentation of new-onset type 1 diabetes to an Australian tertiary centre increased during the in...
33,032,333
Eur J Dent
Utilization of Teledentistry in Antimicrobial Prescribing and Diagnosis of Infectious Diseases during COVID-19 Lockdown.
OBJECTIVES: This study aimed to analyze Jordanian dentists' inquiries on oral infections and antimicrobial prescribing using dental professional WhatsApp groups during coronavirus disease lockdown period. MATERIALS AND METHODS: Three professional WhatsApp groups of Jordanian dentists were reviewed and analyzed for inqu...
Journal Article
Dar-Odeh, Najla;Babkair, Hamzah;Alnazzawi, Ahmad;Abu-Hammad, Shaden;Abu-Hammad, Abdalla;Abu-Hammad, Osama
10.1055/s-0040-1717159
[ 0, 1, 1, 0, 0, 0, 0 ]
[Title]: Utilization of Teledentistry in Antimicrobial Prescribing and Diagnosis of Infectious Diseases during COVID-19 Lockdown. [Abstract]: OBJECTIVES: This study aimed to analyze Jordanian dentists' inquiries on oral infections and antimicrobial prescribing using dental professional WhatsApp groups during coronaviru...
32,497,852
World Neurosurg
Traumatic Nonmissile Penetrating Transnasal Anterior Skull Base Fracture and Brain Injury with Cerebrospinal Fluid Leak: Intraoperative Leak Detection and an Effective Reconstruction Procedure for a Localized Skull Base Defect Especially After Coronavirus Disease 2019 Outbreak.
BACKGROUND: Cerebrospinal fluid (CSF) leakage after penetrating skull base injury is relatively rare compared with close head injuries involving skull base fractures. CASE DESCRIPTION: We report the case of a 65-year-old man who had presented with epistaxis and serous rhinorrhea. When he had fallen to the ground near h...
covid-19 era;cerebrospinal fluid leakage;endonasal endoscopic repair;fat-on-fascia graft;fluorescein;skull base defect;traumatic nonmissile penetrating transnasal skull base fracture
Case Reports
Yoneoka, Yuichiro;Aizawa, Naotaka;Nonomura, Yoriko;Ogi, Manabu;Seki, Yasuhiro;Akiyama, Katsuhiko
10.1016/j.wneu.2020.05.236
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Traumatic Nonmissile Penetrating Transnasal Anterior Skull Base Fracture and Brain Injury with Cerebrospinal Fluid Leak: Intraoperative Leak Detection and an Effective Reconstruction Procedure for a Localized Skull Base Defect Especially After Coronavirus Disease 2019 Outbreak. [Abstract]: BACKGROUND: Cerebros...
32,408,155
Mult Scler Relat Disord
Severe COVID-19 infection in a patient with multiple sclerosis treated with fingolimod.
BACKGROUND: Fingolimod is used for immune therapy in patients with multiple sclerosis. Long-term treatment is associated with a small increase in the risk of herpes virus reactivation and respiratory tract infections. Patients with coronavirus disease 2019 (COVID-19) under Fingolimod treatment have not been described. ...
covid-19;critical care;fingolimod;multiple sclerosis;viral infection
Case Reports
Foerch, Christian;Friedauer, Lucie;Bauer, Boris;Wolf, Timo;Adam, Elisabeth H
10.1016/j.msard.2020.102180
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Severe COVID-19 infection in a patient with multiple sclerosis treated with fingolimod. [Abstract]: BACKGROUND: Fingolimod is used for immune therapy in patients with multiple sclerosis. Long-term treatment is associated with a small increase in the risk of herpes virus reactivation and respiratory tract infec...
32,401,085
Med Teach
Coordinated responses of academic medical centres to pandemics: Sustaining medical education during COVID-19.
Background: The Corona Virus Disease-19 (COVID-19) has been declared a pandemic by the World Health Organization (WHO). We state the consolidated and systematic approach for academic medical centres in response to the evolving pandemic outbreaks for sustaining medical education.Discussion: Academic medical centres need...
e-learning/computers;general;public health;undergraduate
Journal Article
Ashokka, Balakrishnan;Ong, Say Yang;Tay, Kwang Hui;Loh, Ne Hooi Will;Gee, Chen Fun;Samarasekera, Dujeepa D
10.1080/0142159X.2020.1757634
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Coordinated responses of academic medical centres to pandemics: Sustaining medical education during COVID-19. [Abstract]: Background: The Corona Virus Disease-19 (COVID-19) has been declared a pandemic by the World Health Organization (WHO). We state the consolidated and systematic approach for academic medica...
32,602,680
J Assoc Physicians India
Impact of COVID-19 Pandemic on Oncology Practices During Nationwide Lockdown Period: A Single Centre Experience and the Way Forward.
Background: The COVID-19 pandemic has posed a grave challenge to mankind as it doesn't appear to get controlled in the near future. Worldwide, health care centers are working more than their capacity with the scarcity of medical resources. Cancer patients are considered to be at higher risk of developing life-threateni...
Journal Article
Sundriyal, Deepak;Sehrawat, Amit;Kumar, Parmod;Bhandari, Rekha
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of COVID-19 Pandemic on Oncology Practices During Nationwide Lockdown Period: A Single Centre Experience and the Way Forward. [Abstract]: Background: The COVID-19 pandemic has posed a grave challenge to mankind as it doesn't appear to get controlled in the near future. Worldwide, health care centers are...
33,003,634
Int J Environ Res Public Health
Epidemiology of and Risk Factors for COVID-19 Infection among Health Care Workers: A Multi-Centre Comparative Study.
Healthcare workers (HCWs) worldwide are putting themselves at high risks of coronavirus disease 2019 (COVID-19) by treating a large number of patients while lacking protective equipment. We aim to provide a scientific basis for preventing and controlling the COVID-19 infection among HCWs. We used data on COVID-19 cases...
covid-19;attack rate;epidemiology;health care worker;risk factor
Comparative Study;Journal Article;Multicenter Study;Research Support, Non-U.S. Gov't
Wei, Jia-Te;Liu, Zhi-Dong;Fan, Zheng-Wei;Zhao, Lin;Cao, Wu-Chun
10.3390/ijerph17197149
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Epidemiology of and Risk Factors for COVID-19 Infection among Health Care Workers: A Multi-Centre Comparative Study. [Abstract]: Healthcare workers (HCWs) worldwide are putting themselves at high risks of coronavirus disease 2019 (COVID-19) by treating a large number of patients while lacking protective equipm...
32,837,940
Indian J Otolaryngol Head Neck Surg
A Novel Technique of Draping for Otologic Surgery: Mitigation of Aerosol Generation During Covid Pandemic.
The surgical procedures in the temporal bone have the potential to generate aerosols which could affect the health care personnel. An innovative way to avoid aerosolization during ear surgery has been highlighted in this manuscript.
aerosol generating surgery;covid 19 pandemic;draping technique
Journal Article
Panda, Naresh K;Agarwal, Ganesh;Hage, Neemu;Balaji, R
10.1007/s12070-020-01983-x
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: A Novel Technique of Draping for Otologic Surgery: Mitigation of Aerosol Generation During Covid Pandemic. [Abstract]: The surgical procedures in the temporal bone have the potential to generate aerosols which could affect the health care personnel. An innovative way to avoid aerosolization during ear surgery ...
32,623,350
J Clin Virol
Multiplex detection and dynamics of IgG antibodies to SARS-CoV2 and the highly pathogenic human coronaviruses SARS-CoV and MERS-CoV.
BACKGROUND: Knowledge of the COVID-19 epidemic extent and the level of herd immunity is urgently needed to help manage this pandemic. METHODS: We used a panel of 167 samples (77 pre-epidemic and 90 COVID-19 seroconverters) and SARS-CoV1, SARS-CoV2 and MERS-CoV Spike and/or Nucleopcapsid (NC) proteins to develop a high ...
covid-19;luminex;sars;sars-cov2;serology
Evaluation Study;Journal Article;Research Support, Non-U.S. Gov't
Ayouba, Ahidjo;Thaurignac, Guillaume;Morquin, David;Tuaillon, Edouard;Raulino, Raisa;Nkuba, Antoine;Lacroix, Audrey;Vidal, Nicole;Foulongne, Vincent;Le Moing, Vincent;Reynes, Jacques;Delaporte, Eric;Peeters, Martine
10.1016/j.jcv.2020.104521
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Multiplex detection and dynamics of IgG antibodies to SARS-CoV2 and the highly pathogenic human coronaviruses SARS-CoV and MERS-CoV. [Abstract]: BACKGROUND: Knowledge of the COVID-19 epidemic extent and the level of herd immunity is urgently needed to help manage this pandemic. METHODS: We used a panel of 167 ...
32,529,405
Clin Auton Res
Autonomic function testing in the COVID-19 pandemic: an American Autonomic Society position statement.
COVID-19 is a global pandemic that is wreaking havoc with the health and economy of much of human civilization. In this document from the American Autonomic Society, we identify the potential risks of exposure to patients, physicians, and allied healthcare staff. We provide guidance for conducting autonomic function te...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't;Review
Figueroa, Juan J;Cheshire, William P;Claydon, Victoria E;Norcliffe-Kaufmann, Lucy;Peltier, Amanda;Singer, Wolfgang;Snapper, Howard;Vernino, Steven;Raj, Satish R
10.1007/s10286-020-00702-4
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Autonomic function testing in the COVID-19 pandemic: an American Autonomic Society position statement. [Abstract]: COVID-19 is a global pandemic that is wreaking havoc with the health and economy of much of human civilization. In this document from the American Autonomic Society, we identify the potential risk...
32,541,583
Anesth Analg
To Protect Health Care Workers Better, To Save More Lives With COVID-19.
The coronavirus disease 2019 (COVID-19) pandemic has thus far caused a total of 81,747 confirmed cases with 3283 deaths in China and more than 370,000 confirmed cases including over 16,000 deaths around the world by March 24, 2020. This issue has received extensive attention from the international community and has bec...
Historical Article;Journal Article;Review
Chen, Weiyun;Huang, Yuguang
10.1213/ANE.0000000000004834
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: To Protect Health Care Workers Better, To Save More Lives With COVID-19. [Abstract]: The coronavirus disease 2019 (COVID-19) pandemic has thus far caused a total of 81,747 confirmed cases with 3283 deaths in China and more than 370,000 confirmed cases including over 16,000 deaths around the world by March 24, ...
32,905,939
Diabetes Metab Syndr
No benefit of hydroxychloroquine in COVID-19: Results of Systematic Review and Meta-Analysis of Randomized Controlled Trials".
BACKGROUND AND AIMS: Coronavirus pandemic is currently a global public health emergency with no definitive treatment guidelines. We conducted a systematic review and meta-analysis of the literature evaluating the efficacy of hydroxychloroquine and its related formulations in COVID-19 patients. METHODS: A systematic sea...
covid-19;chloroquine;hydroxychloroquine;mortality;sars-cov-2 infection
Journal Article;Meta-Analysis;Systematic Review
Pathak, Dr Subodh Kumar;Salunke, Dr Abhijeet Ashok;Thivari, Dr Praveen;Pandey, Apurva;Nandy, Dr Kunal;Harish V K Ratna, Dr;Pandey, Dr Sanjay;Chawla, Dr Jasneet;Mujawar, Dr Jalil;Dhanwate, Dr Anant;Menon, Dr Vivek
10.1016/j.dsx.2020.08.033
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: No benefit of hydroxychloroquine in COVID-19: Results of Systematic Review and Meta-Analysis of Randomized Controlled Trials". [Abstract]: BACKGROUND AND AIMS: Coronavirus pandemic is currently a global public health emergency with no definitive treatment guidelines. We conducted a systematic review and meta-a...
32,565,366
Int J Infect Dis
Acute respiratory distress syndrome due to SARS-CoV-2 and Influenza A co-infection in an Italian patient: Mini-review of the literature.
A case of acute respiratory distress syndrome due to SARS-CoV-2 and Influenza A co-infection and a mini-review of the literature is reported. Even in COVID-19 epidemics, the early identification of concurrent respiratory pathogens is important to improve etiological diagnosis, preventive measures and patients' clinical...
acute respiratory distress syndrome;covid-19 epidemic;influenza a;sars-cov-2
Case Reports
D'Abramo, Alessandra;Lepore, Luciana;Palazzolo, Claudia;Barreca, Filippo;Liuzzi, Giuseppina;Lalle, Eleonora;Nicastri, Emanuele
10.1016/j.ijid.2020.06.056
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Acute respiratory distress syndrome due to SARS-CoV-2 and Influenza A co-infection in an Italian patient: Mini-review of the literature. [Abstract]: A case of acute respiratory distress syndrome due to SARS-CoV-2 and Influenza A co-infection and a mini-review of the literature is reported. Even in COVID-19 epi...
33,067,091
Acad Radiol
Imaging Features of Pediatric COVID-19 on Chest Radiography and Chest CT: A Retrospective, Single-Center Study.
RATIONALE AND OBJECTIVES: This study aims to reveal the imaging features of Coronavirus Disease 2019 (COVID-19) in children. MATERIALS AND METHODS: Sixty-nine chest radiographs and 37 chest CT examinations of 74 children (36 male; median (interquartile range) age:11 (6.25-15) years, 38 female; median (interquartile ran...
covid-19;ct;children;lung;radiography
Journal Article
Bayramoglu, Zuhal;Canipek, Eda;Comert, Rana G;Gasimli, Nilufar;Kaba, Ozge;Sari Yanartas, Mehpare;Hancerli Torun, Selda;Somer, Ayper;Erturk, Sukru Mehmet
10.1016/j.acra.2020.10.002
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Imaging Features of Pediatric COVID-19 on Chest Radiography and Chest CT: A Retrospective, Single-Center Study. [Abstract]: RATIONALE AND OBJECTIVES: This study aims to reveal the imaging features of Coronavirus Disease 2019 (COVID-19) in children. MATERIALS AND METHODS: Sixty-nine chest radiographs and 37 che...
32,573,254
Bioanalysis
Laboratory considerations amidst the coronavirus disease 2019 outbreak: the Spedali Civili in Brescia experience.
Coronavirus disease 2019 emergency has created an enormous stress on providers that have been transformed into coronavirus disease hospitals. This article presents the experience of the clinical laboratory of Spedali Civili in Brescia (a teaching hospital in Lombardy with over 1500 beds) in managing the crisis, and to ...
covid hospital;covid-19 emergency;lab organization;panels for monitoring patients;reagents;staff management
Journal Article
Garrafa, Emirena;Brugnoni, Duilio;Barbaro, Mose;Andreoli, Laura;Foca, Emanuele;Salvetti, Massimo;Castelli, Francesco;Franceschini, Franco;Piva, Simone;Muiesan, Maria Lorenza;Latronico, Nicola;Levaggi, Rosella
10.4155/bio-2020-0109
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Laboratory considerations amidst the coronavirus disease 2019 outbreak: the Spedali Civili in Brescia experience. [Abstract]: Coronavirus disease 2019 emergency has created an enormous stress on providers that have been transformed into coronavirus disease hospitals. This article presents the experience of the...
32,942,077
Eur J Obstet Gynecol Reprod Biol
Effects of SARS Cov-2 epidemic on the obstetrical and gynecological emergency service accesses. What happened and what shall we expect now?
OBJECTIVE: During the lockdown period, the fear about the risk of infection in hospital has reduced the admission to Emergency Services (ES) with possible negative health effects. We have investigated the changes in the emergency flow occurred during SARS-CoV-2 pandemic in an obstetrics and gynecological ES and the sho...
birth;covid-19;emergency service;fetal death;pregnancy
Comparative Study;Journal Article
Dell'Utri, Chiara;Manzoni, Elisabetta;Cipriani, Sonia;Spizzico, Claudio;Dell'Acqua, Andrea;Barbara, Giussy;Parazzini, Fabio;Kustermann, Alessandra
10.1016/j.ejogrb.2020.09.006
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Effects of SARS Cov-2 epidemic on the obstetrical and gynecological emergency service accesses. What happened and what shall we expect now? [Abstract]: OBJECTIVE: During the lockdown period, the fear about the risk of infection in hospital has reduced the admission to Emergency Services (ES) with possible nega...
32,565,229
Reprod Biomed Online
SARS-CoV-2: diagnostic and design conundrums in the context of male factor infertility.
The question of whether SARS-CoV-2 (severe acute respiratory syndrome-related coronavirus-2 [SARS-CoV-2], leading to the COVID-19 infection) can be harboured in the testes and/or semen is currently unanswered. It is essential to understand the limitations of both antibody and real-time PCR tests in interpreting SARS-Co...
covid-19;diagnosis;infertility;male factor;sars-cov-2;semen
Journal Article
Bahadur, Gulam;Acharya, Santanu;Muneer, Asif;Huirne, Judith;Lukaszuk, Mariusz;Doreski, Pablo Alexis;Homburg, Roy
10.1016/j.rbmo.2020.05.014
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: SARS-CoV-2: diagnostic and design conundrums in the context of male factor infertility. [Abstract]: The question of whether SARS-CoV-2 (severe acute respiratory syndrome-related coronavirus-2 [SARS-CoV-2], leading to the COVID-19 infection) can be harboured in the testes and/or semen is currently unanswered. I...
33,014,647
Cureus
24 Hours: A Case of Multiorgan Failure Associated With COVID-19.
Coronavirus has caused thousands of deaths due to several mechanisms of injury including acute kidney injury (AKI). Most of the patients have a fast progression of the disease leading to death in the second week of hospital admission, however, here we have a case of a 58-year-old female who died in less than 24 hours o...
acidosis;covid-19;cytokine storm;hemodialysis;mortality;renal failure;risk factors
Case Reports
Espinoza, Diana;Rodriguez, Raul;Kowalski, Andrew
10.7759/cureus.10149
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: 24 Hours: A Case of Multiorgan Failure Associated With COVID-19. [Abstract]: Coronavirus has caused thousands of deaths due to several mechanisms of injury including acute kidney injury (AKI). Most of the patients have a fast progression of the disease leading to death in the second week of hospital admission,...
32,914,775
Recenti Prog Med
[Acro-ischemic injuries in children-adolescents during CoViD-19 pandemic: from lifestyle changes due to lockdown to interferone.]
At the end of March 2020, just over a month after the first ascertained case of CoViD-19 infection in Italy, the first reports of acute lesions of acro-ischemia appeared, especially in pre-adolescents and adolescents. These manifestations have been called in the course of these months in various ways, from "acro-ischem...
Journal Article
Marchetti, Federico;Guiducci, Claudia;Bigucci, Barbara;Iacono, Alessandra;Calderoni, Ombretta;Sorci, Maria Rita;Sparacino, Monica;Semprini, Simona;Vergine, Gianluca
10.1701/3421.34060
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: [Acro-ischemic injuries in children-adolescents during CoViD-19 pandemic: from lifestyle changes due to lockdown to interferone.] [Abstract]: At the end of March 2020, just over a month after the first ascertained case of CoViD-19 infection in Italy, the first reports of acute lesions of acro-ischemia appeared...
33,034,674
HNO
Quality of cochlear implant rehabilitation under COVID-19 conditions.
BACKGROUND: The rehabilitation process following cochlear implant (CI) surgery is carried out in a multimodal therapy according to German national guidelines and includes technical and medical aftercare. In times of the corona pandemic surgery and rehabilitation appointments were cancelled or delayed leading to a more ...
aftercare;quality assurance;severe acute respiratory syndrome coronavirus 2;speech therapy;standard of care
Journal Article
Aschendorff, A;Arndt, S;Kroger, S;Wesarg, T;Ketterer, M C;Kirchem, P;Pixner, S;Hassepass, F;Beck, R
10.1007/s00106-020-00923-z
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Quality of cochlear implant rehabilitation under COVID-19 conditions. [Abstract]: BACKGROUND: The rehabilitation process following cochlear implant (CI) surgery is carried out in a multimodal therapy according to German national guidelines and includes technical and medical aftercare. In times of the corona pa...
32,953,307
Cureus
Paying in Blood: A Case of Thrombocytopenia in Covid-19.
Novel coronavirus disease 2019 (COVID-19) primarily involves the respiratory system. Consumptive coagulopathy is seen in acute respiratory distress syndrome (ARDS) and multi-organ failure (MOF). Usually, only severely sick patients develop mild thrombocytopenia. We present a case of mildly symptomatic young adult, pres...
covid 19;covid associated thrombocytopenia;thrombocytopenia
Case Reports
Malik, Jahanzeb;Javaid, Muhammad;Majedi, Omaid;Ishaq, Uzma;Zahid, Tayyaba
10.7759/cureus.9791
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Paying in Blood: A Case of Thrombocytopenia in Covid-19. [Abstract]: Novel coronavirus disease 2019 (COVID-19) primarily involves the respiratory system. Consumptive coagulopathy is seen in acute respiratory distress syndrome (ARDS) and multi-organ failure (MOF). Usually, only severely sick patients develop mi...
32,991,251
Physiol Genomics
The COVID-19 pandemic: a global health crisis.
The novel coronavirus SARS-CoV-2 was identified as the causative agent for a series of atypical respiratory diseases in the Hubei Province of Wuhan, China in December of 2019. The disease SARS-CoV-2, termed COVID-19, was officially declared a pandemic by the World Health Organization on March 11, 2020. SARS-CoV-2 conta...
ards;covid-19;gtpases;genetics;pulmonary fibrosis
Journal Article;Research Support, Non-U.S. Gov't;Review
Pollard, Casey A;Morran, Michael P;Nestor-Kalinoski, Andrea L
10.1152/physiolgenomics.00089.2020
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The COVID-19 pandemic: a global health crisis. [Abstract]: The novel coronavirus SARS-CoV-2 was identified as the causative agent for a series of atypical respiratory diseases in the Hubei Province of Wuhan, China in December of 2019. The disease SARS-CoV-2, termed COVID-19, was officially declared a pandemic ...
32,965,010
Eur Rev Med Pharmacol Sci
SARS-CoV-2 infection: NLRP3 inflammasome as plausible target to prevent cardiopulmonary complications?
NLRP3 (NOD-, LRR- and pyrin domain-containing protein 3) inflammasome has recently become an intriguing target of several chronic and viral diseases. Here, we argue that targeting NLRP3 inflammasome could be a strategy to prevent cardiovascular outcomes [fulminant myocarditis, heart failure, venous thromboembolism (VTE...
Journal Article;Research Support, Non-U.S. Gov't
Quagliariello, V;Bonelli, A;Caronna, A;Lombari, M C;Conforti, G;Libutti, M;Iaffaioli, R V;Berretta, M;Botti, G;Maurea, N
10.26355/eurrev_202009_22867
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: SARS-CoV-2 infection: NLRP3 inflammasome as plausible target to prevent cardiopulmonary complications? [Abstract]: NLRP3 (NOD-, LRR- and pyrin domain-containing protein 3) inflammasome has recently become an intriguing target of several chronic and viral diseases. Here, we argue that targeting NLRP3 inflammaso...
32,292,906
Med Drug Discov
The role of afferent pulmonary innervation in ARDS associated with COVID-19 and potential use of resiniferatoxin to improve prognosis: A review.
Acute respiratory distress syndrome (ARDS) is one of the major causes of mortality associated with COVID-19 disease. Many patients will require intensive care with ventilatory support. Despite progress and best efforts, the mortality rates projected remain high. Historical data outlook points towards 80% expected fatal...
ards;covid-19;sars-cov-2;trpv1;cytokine;inflammation;lung;resiniferatoxin
Journal Article;Review
Nahama, Alexis;Ramachandran, Roshni;Cisternas, Alvaro Francisco;Ji, Henry
10.1016/j.medidd.2020.100033
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The role of afferent pulmonary innervation in ARDS associated with COVID-19 and potential use of resiniferatoxin to improve prognosis: A review. [Abstract]: Acute respiratory distress syndrome (ARDS) is one of the major causes of mortality associated with COVID-19 disease. Many patients will require intensive ...
32,301,767
J Orthop Trauma
The Orthopaedic Trauma Service and COVID-19: Practice Considerations to Optimize Outcomes and Limit Exposure.
The COVID-19 pandemic has presented challenges to healthcare systems, including the cancellation and then staged resumption of elective procedures. The orthopaedic trauma community has continued to provide care to patients with acute musculoskeletal injuries that cannot be delayed in all scenarios. This article summari...
Case Reports;Journal Article
Stinner, Daniel J;Lebrun, Christopher;Hsu, Joseph R;Jahangir, A Alex;Mir, Hassan R
10.1097/BOT.0000000000001782
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Orthopaedic Trauma Service and COVID-19: Practice Considerations to Optimize Outcomes and Limit Exposure. [Abstract]: The COVID-19 pandemic has presented challenges to healthcare systems, including the cancellation and then staged resumption of elective procedures. The orthopaedic trauma community has cont...
32,844,136
J Vasc Surg Cases Innov Tech
Acute upper limb ischemia as the first manifestation in a patient with COVID-19.
Coronavirus disease-19 (COVID-19) first emerged in December 2019 in China and rapidly spread worldwide. Although various studies have reported that COVID-19 is associated with a hypercoagulable state and thrombotic complications in critically ill patients, there are few case reports on thrombotic events as one of the p...
acute limb ischemia;anticoagulation;covid-19;coronavirus;hypercoagulable state
Case Reports
Shao, Tony;In-Bok Lee, Christina;Jabori, Sinan;Rey, Jorge;Duran, Elizabeth Ramos;Kang, Naixin
10.1016/j.jvscit.2020.08.003
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Acute upper limb ischemia as the first manifestation in a patient with COVID-19. [Abstract]: Coronavirus disease-19 (COVID-19) first emerged in December 2019 in China and rapidly spread worldwide. Although various studies have reported that COVID-19 is associated with a hypercoagulable state and thrombotic com...
32,904,593
Drug Des Devel Ther
A Single Large Dose of Vitamin D Could be Used as a Means of Coronavirus Disease 2019 Prevention and Treatment.
There is no specific and effective medication for coronavirus disease 2019 (COVID-19), and avaccine is not available in recent months. Here, we hypothesize that a single large dose of vitamin D (Vit D) could be an option for trial in COVID-19. Vit D deficiency or insufficiency is very common in the general population a...
coronavirus disease 2019;large dose;vitamin d
Journal Article
Liu, Guoqiang;Hong, Tianpei;Yang, Jin
10.2147/DDDT.S271754
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: A Single Large Dose of Vitamin D Could be Used as a Means of Coronavirus Disease 2019 Prevention and Treatment. [Abstract]: There is no specific and effective medication for coronavirus disease 2019 (COVID-19), and avaccine is not available in recent months. Here, we hypothesize that a single large dose of vit...
32,871,424
Clin Imaging
Spontaneous subcutaneous emphysema and pneumomediastinum in non-intubated patients with COVID-19.
PURPOSE: We describe the presenting characteristics and hospital course of 11 novel coronavirus (COVID-19) patients who developed spontaneous subcutaneous emphysema (SE) with or without pneumomediastinum (SPM) in the absence of prior mechanical ventilation. MATERIALS AND METHODS: A total of 11 non-intubated COVID-19 pa...
covid-19;pneumomediastinum;subcutaneous emphysema
Case Reports
Manna, Sayan;Maron, Samuel Z;Cedillo, Mario A;Voutsinas, Nicholas;Toussie, Danielle;Finkelstein, Mark;Steinberger, Sharon;Chung, Michael;Bernheim, Adam;Eber, Corey;Gupta, Yogesh Sean;Concepcion, Jose;Libes, Richard;Jacobi, Adam
10.1016/j.clinimag.2020.08.013
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Spontaneous subcutaneous emphysema and pneumomediastinum in non-intubated patients with COVID-19. [Abstract]: PURPOSE: We describe the presenting characteristics and hospital course of 11 novel coronavirus (COVID-19) patients who developed spontaneous subcutaneous emphysema (SE) with or without pneumomediastin...
32,484,220
Brief Bioinform
Discovery of G-quadruplex-forming sequences in SARS-CoV-2.
The outbreak caused by the novel coronavirus SARS-CoV-2 has been declared a global health emergency. G-quadruplex structures in genomes have long been considered essential for regulating a number of biological processes in a plethora of organisms. We have analyzed and identified 25 four contiguous GG runs (G2NxG2NyG2Nz...
coronaviridae;g-quadruplex;pqss;sars-cov-2;helicase inhibitor;viral helicase nsp13
Journal Article;Research Support, Non-U.S. Gov't
Ji, Danyang;Juhas, Mario;Tsang, Chi Man;Kwok, Chun Kit;Li, Yongshu;Zhang, Yang
10.1093/bib/bbaa114
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Discovery of G-quadruplex-forming sequences in SARS-CoV-2. [Abstract]: The outbreak caused by the novel coronavirus SARS-CoV-2 has been declared a global health emergency. G-quadruplex structures in genomes have long been considered essential for regulating a number of biological processes in a plethora of org...
32,496,210
Antivir Ther
Combination antiviral therapy with lopinavir/ritonavir, arbidol and interferon-alpha1b for COVID-19.
Since the outbreak of coronavirus disease (COVID-19) that was discovered in 2019 in Wuhan, China, no standard therapy guideline has been set despite the severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its high infectivity. The globally pandemic outbreak suggests that COVID-19 is highly infe...
Case Reports;Journal Article;Research Support, Non-U.S. Gov't
Xie, Xiangyang;Jiang, Yuanliang;Zeng, Yuan;Liu, Hui
10.3851/IMP3362
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Combination antiviral therapy with lopinavir/ritonavir, arbidol and interferon-alpha1b for COVID-19. [Abstract]: Since the outbreak of coronavirus disease (COVID-19) that was discovered in 2019 in Wuhan, China, no standard therapy guideline has been set despite the severity of severe acute respiratory syndrome...
32,862,110
Int Immunopharmacol
Overview of the current promising approaches for the development of an effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine.
Coronavirus disease 2019 (COVID-19) is a pandemic infectious disease caused by the novel coronavirus called SARS-CoV-2. There is a gap in our understanding regarding the immunopathogenesis of COVID-19. However, many clinical trials are underway across the world for screening effective drugs against COVID-19. Neverthele...
covid-19;immunopathogenesis;sars-cov-2;vaccines
Journal Article;Review
Mirzaei, Rasoul;Mohammadzadeh, Rokhsareh;Mahdavi, Farzad;Badrzadeh, Fariba;Kazemi, Sheida;Ebrahimi, Mehdi;Soltani, Fatemeh;Kazemi, Sima;Jeda, Ali Salimi;Darvishmotevalli, Mohammad;Yousefimashouf, Rasoul;Keyvani, Hossein;Karampoor, Sajad
10.1016/j.intimp.2020.106928
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Overview of the current promising approaches for the development of an effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine. [Abstract]: Coronavirus disease 2019 (COVID-19) is a pandemic infectious disease caused by the novel coronavirus called SARS-CoV-2. There is a gap in our unders...
32,618,932
Pediatr Infect Dis J
Duration of Respiratory and Gastrointestinal Viral Shedding in Children With SARS-CoV-2: A Systematic Review and Synthesis of Data.
BACKGROUND: Children with coronavirus disease 2019 (COVID-19) are more likely to have mild or no symptoms compared with adults and may represent important vectors for transmitting the virus. Little is known about the duration of respiratory and gastrointestinal viral shedding in children with COVID-19. OBJECTIVE: To de...
Journal Article;Systematic Review
Xu, Cecilia L H;Raval, Manjri;Schnall, Jesse A;Kwong, Jason C;Holmes, Natasha E
10.1097/INF.0000000000002814
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Duration of Respiratory and Gastrointestinal Viral Shedding in Children With SARS-CoV-2: A Systematic Review and Synthesis of Data. [Abstract]: BACKGROUND: Children with coronavirus disease 2019 (COVID-19) are more likely to have mild or no symptoms compared with adults and may represent important vectors for ...
32,423,435
BMC Pediatr
Chest CT imaging characteristics of COVID-19 pneumonia in preschool children: a retrospective study.
BACKGROUND: Recently, the World Health Organization has declared the coronavirus disease 2019 (COVID-19) outbreak a public health emergency of international concern. So far, however, limited data are available for children. Therefore, we aimed to investigate the clinical and chest CT imaging characteristics of COVID-19...
covid-19;child;multidetector computed tomography;pneumonia;sars-cov-2
Journal Article
Li, Yang;Cao, Jianghui;Zhang, Xiaolong;Liu, Guangzhi;Wu, Xiaxia;Wu, Baolin
10.1186/s12887-020-02140-7
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Chest CT imaging characteristics of COVID-19 pneumonia in preschool children: a retrospective study. [Abstract]: BACKGROUND: Recently, the World Health Organization has declared the coronavirus disease 2019 (COVID-19) outbreak a public health emergency of international concern. So far, however, limited data ar...