row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:11270 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,270 | train | mutant | 3,798,037 | 225 | 3,801,982 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190F | L190F | 1 | 1 | 0 | 0 | 190 | L | F | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,094,268 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.5075 | 0.098344 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181218,"numValue":-0.50749954371711,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181219,"numValue":0.0983443464605373,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11271 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,271 | train | mutant | 3,798,038 | 225 | 3,801,983 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190G | L190G | 1 | 1 | 0 | 0 | 190 | L | G | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 3,851,286 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.590519 | 0.067887 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9695254,"numValue":0.590519028645069,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9695255,"numValue":0.0678870605886896,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11272 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,272 | train | mutant | 3,798,038 | 225 | 3,801,983 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190G | L190G | 1 | 1 | 0 | 0 | 190 | L | G | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,093,315 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.737131 | 0.034024 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179312,"numValue":-0.737131108614531,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179313,"numValue":0.0340236119320546,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11273 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,273 | train | mutant | 3,798,038 | 225 | 3,801,983 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190G | L190G | 1 | 1 | 0 | 0 | 190 | L | G | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,094,269 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.596377 | 0.06888 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181220,"numValue":-0.596376522957651,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181221,"numValue":0.0688801284385175,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11274 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,274 | train | mutant | 3,798,039 | 225 | 3,801,984 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190H | L190H | 1 | 1 | 0 | 0 | 190 | L | H | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 3,851,287 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.314878 | 0.053095 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9695256,"numValue":0.314877938098434,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9695257,"numValue":0.053094723487796,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11275 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,275 | train | mutant | 3,798,039 | 225 | 3,801,984 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190H | L190H | 1 | 1 | 0 | 0 | 190 | L | H | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,093,316 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.401998 | 0.102336 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179314,"numValue":-0.401997912853065,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179315,"numValue":0.102335786642071,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11276 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,276 | train | mutant | 3,798,039 | 225 | 3,801,984 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190H | L190H | 1 | 1 | 0 | 0 | 190 | L | H | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,094,270 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.697383 | 0.195922 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181222,"numValue":-0.69738346014079,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181223,"numValue":0.195922141209406,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11277 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,277 | train | mutant | 3,798,040 | 225 | 3,801,985 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190I | L190I | 1 | 1 | 0 | 0 | 190 | L | I | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 3,851,288 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.112987 | 0.119565 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9695258,"numValue":-0.112987143464032,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9695259,"numValue":0.119564881348261,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11278 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,278 | train | mutant | 3,798,040 | 225 | 3,801,985 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190I | L190I | 1 | 1 | 0 | 0 | 190 | L | I | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,093,317 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.081337 | 0.076734 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179316,"numValue":0.081337407762695,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179317,"numValue":0.0767339276074082,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11279 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,279 | train | mutant | 3,798,040 | 225 | 3,801,985 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190I | L190I | 1 | 1 | 0 | 0 | 190 | L | I | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,094,271 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.080293 | 0.082708 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181224,"numValue":0.0802930316845568,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181225,"numValue":0.082708066459594,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11280 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,280 | train | mutant | 3,798,041 | 225 | 3,801,986 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190K | L190K | 1 | 1 | 0 | 0 | 190 | L | K | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 3,851,289 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.027485 | 0.160237 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9695260,"numValue":0.027485100851262,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9695261,"numValue":0.160237463199582,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11281 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,281 | train | mutant | 3,798,041 | 225 | 3,801,986 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190K | L190K | 1 | 1 | 0 | 0 | 190 | L | K | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,093,318 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.146768 | 0.055032 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179318,"numValue":-0.146767612008287,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179319,"numValue":0.0550322668576508,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11282 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,282 | train | mutant | 3,798,041 | 225 | 3,801,986 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190K | L190K | 1 | 1 | 0 | 0 | 190 | L | K | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,094,272 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.11033 | 0.072983 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181226,"numValue":-0.110330008981079,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181227,"numValue":0.0729825833618342,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11283 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,283 | train | mutant | 3,798,042 | 225 | 3,801,987 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190M | L190M | 1 | 1 | 0 | 0 | 190 | L | M | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 3,851,290 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.011058 | 0.073514 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9695262,"numValue":-0.0110581422890211,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9695263,"numValue":0.0735138519468324,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11284 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,284 | train | mutant | 3,798,042 | 225 | 3,801,987 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190M | L190M | 1 | 1 | 0 | 0 | 190 | L | M | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,093,739 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.066499 | 0.035831 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180160,"numValue":-0.066499145115627,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180161,"numValue":0.0358312533102539,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11285 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,285 | train | mutant | 3,798,042 | 225 | 3,801,987 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190M | L190M | 1 | 1 | 0 | 0 | 190 | L | M | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,094,673 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.187342 | 0.071598 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182028,"numValue":0.187341666382145,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182029,"numValue":0.0715975315773362,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11286 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,286 | train | mutant | 3,798,043 | 225 | 3,801,988 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190N | L190N | 1 | 1 | 0 | 0 | 190 | L | N | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 3,851,291 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.444491 | 0.09401 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9695264,"numValue":0.444490720234898,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9695265,"numValue":0.0940096750323007,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11288 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,288 | train | mutant | 3,798,043 | 225 | 3,801,988 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190N | L190N | 1 | 1 | 0 | 0 | 190 | L | N | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,094,674 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.31851 | 0.13077 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182030,"numValue":-0.318510173863758,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182031,"numValue":0.130770348502679,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11289 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,289 | train | mutant | 3,798,044 | 225 | 3,801,989 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190P | L190P | 1 | 1 | 0 | 0 | 190 | L | P | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 3,851,292 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.734269 | 0.219955 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9695266,"numValue":0.734268722554673,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9695267,"numValue":0.219955475931399,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11290 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,290 | train | mutant | 3,798,044 | 225 | 3,801,989 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190P | L190P | 1 | 1 | 0 | 0 | 190 | L | P | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,093,741 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.689387 | 0.080055 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180164,"numValue":-0.689387379544542,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180165,"numValue":0.0800548962778536,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11291 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,291 | train | mutant | 3,798,044 | 225 | 3,801,989 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190P | L190P | 1 | 1 | 0 | 0 | 190 | L | P | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,094,675 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.813269 | 0.131286 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182032,"numValue":-0.813269126359079,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182033,"numValue":0.131286084154104,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11292 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,292 | train | mutant | 3,798,045 | 225 | 3,801,990 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190Q | L190Q | 1 | 1 | 0 | 0 | 190 | L | Q | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 3,851,293 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.147929 | 0.066743 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9695268,"numValue":0.147929031170492,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9695269,"numValue":0.0667432916007184,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11293 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,293 | train | mutant | 3,798,045 | 225 | 3,801,990 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190Q | L190Q | 1 | 1 | 0 | 0 | 190 | L | Q | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,093,742 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.164475 | 0.083423 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180166,"numValue":-0.164474755307904,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180167,"numValue":0.0834232928539301,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11294 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,294 | train | mutant | 3,798,045 | 225 | 3,801,990 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190Q | L190Q | 1 | 1 | 0 | 0 | 190 | L | Q | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,094,676 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.428582 | 0.070254 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182034,"numValue":-0.428582208711103,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182035,"numValue":0.0702540745783022,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11295 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,295 | train | mutant | 3,798,046 | 225 | 3,801,991 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190R | L190R | 1 | 1 | 0 | 0 | 190 | L | R | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 3,851,294 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.184323 | 0.051941 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9695270,"numValue":0.184323329835369,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9695271,"numValue":0.051940532150655,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11296 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,296 | train | mutant | 3,798,046 | 225 | 3,801,991 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190R | L190R | 1 | 1 | 0 | 0 | 190 | L | R | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,093,743 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.212715 | 0.039815 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180168,"numValue":-0.212714881952886,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180169,"numValue":0.0398152191391876,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11297 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,297 | train | mutant | 3,798,046 | 225 | 3,801,991 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190R | L190R | 1 | 1 | 0 | 0 | 190 | L | R | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,094,677 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.284803 | 0.047888 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182036,"numValue":-0.284802734922701,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182037,"numValue":0.0478877384451286,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11298 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,298 | train | mutant | 3,798,047 | 225 | 3,801,992 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190S | L190S | 1 | 1 | 0 | 0 | 190 | L | S | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 3,851,295 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.35449 | 0.043709 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9695272,"numValue":0.354489650385594,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9695273,"numValue":0.0437086452477136,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11301 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,301 | train | mutant | 3,798,048 | 225 | 3,801,993 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190T | L190T | 1 | 1 | 0 | 0 | 190 | L | T | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 3,851,296 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.169983 | 0.067947 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9695274,"numValue":0.169983068600076,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9695275,"numValue":0.0679472867331415,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11303 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,303 | train | mutant | 3,798,048 | 225 | 3,801,993 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190T | L190T | 1 | 1 | 0 | 0 | 190 | L | T | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,094,679 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.38826 | 0.046987 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182040,"numValue":-0.388260284632288,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182041,"numValue":0.0469872953231717,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11304 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,304 | train | mutant | 3,798,049 | 225 | 3,801,994 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190V | L190V | 1 | 1 | 0 | 0 | 190 | L | V | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 3,851,297 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.093649 | 0.10024 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9695276,"numValue":-0.0936486444969714,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9695277,"numValue":0.100240020782403,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11305 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,305 | train | mutant | 3,798,049 | 225 | 3,801,994 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190V | L190V | 1 | 1 | 0 | 0 | 190 | L | V | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,093,746 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.073317 | 0.04324 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180174,"numValue":-0.0733167252507664,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180175,"numValue":0.0432400215638878,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11306 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,306 | train | mutant | 3,798,049 | 225 | 3,801,994 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190V | L190V | 1 | 1 | 0 | 0 | 190 | L | V | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,094,680 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.101113 | 0.07138 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182042,"numValue":-0.101113103461253,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182043,"numValue":0.0713802379800753,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11307 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,307 | train | mutant | 3,798,050 | 225 | 3,801,995 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190W | L190W | 1 | 1 | 0 | 0 | 190 | L | W | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 3,851,298 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.309497 | 0.053398 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9695278,"numValue":0.30949687989727,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9695279,"numValue":0.0533975702630119,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11308 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,308 | train | mutant | 3,798,050 | 225 | 3,801,995 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190W | L190W | 1 | 1 | 0 | 0 | 190 | L | W | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,093,747 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.487309 | 0.039374 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180176,"numValue":-0.487308676807701,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180177,"numValue":0.0393735449550045,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11309 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,309 | train | mutant | 3,798,050 | 225 | 3,801,995 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | L190W | L190W | 1 | 1 | 0 | 0 | 190 | L | W | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,094,681 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.556758 | 0.041595 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182044,"numValue":-0.556758074497366,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182045,"numValue":0.0415949626439812,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11310 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,310 | train | mutant | 4,905,677 | 225 | 4,912,265 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delL190 | delL190 | 1 | 0 | 1 | 0 | 190 | L | - | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,093,309 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.059598 | 0.129018 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179300,"numValue":-1.05959793522395,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179301,"numValue":0.129018117184376,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11311 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,311 | train | mutant | 4,905,677 | 225 | 4,912,265 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delL190 | delL190 | 1 | 0 | 1 | 0 | 190 | L | - | 8 | CONSERVATION | 1K9Q | 347 | null | 190 | A | E | false | false | 10.884046 | null | 5,094,263 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.098114 | 0.197035 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181208,"numValue":-1.09811445536265,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181209,"numValue":0.197034690097144,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16854,"numValue":8.0,"position":190,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11312 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,312 | train | mutant | 3,799,342 | 225 | 3,803,287 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191A | N191A | 1 | 1 | 0 | 0 | 191 | N | A | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 3,852,592 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.879547 | 0.119704 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9697866,"numValue":0.879546570061715,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9697867,"numValue":0.119704427398849,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11313 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,313 | train | mutant | 3,799,342 | 225 | 3,803,287 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191A | N191A | 1 | 1 | 0 | 0 | 191 | N | A | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,093,320 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.995368 | 0.073902 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179322,"numValue":-0.995367932565815,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179323,"numValue":0.0739023220978172,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11314 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,314 | train | mutant | 3,799,342 | 225 | 3,803,287 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191A | N191A | 1 | 1 | 0 | 0 | 191 | N | A | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,094,274 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.968996 | 0.105685 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181230,"numValue":-0.968996346140125,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181231,"numValue":0.105685269749608,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11316 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,316 | train | mutant | 3,799,343 | 225 | 3,803,288 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191C | N191C | 1 | 1 | 0 | 0 | 191 | N | C | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,093,321 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.168743 | 0.06197 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179324,"numValue":-0.168742541617371,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179325,"numValue":0.0619697583719355,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11317 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,317 | train | mutant | 3,799,343 | 225 | 3,803,288 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191C | N191C | 1 | 1 | 0 | 0 | 191 | N | C | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,094,275 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.038376 | 0.062669 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181232,"numValue":-0.0383757785534444,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181233,"numValue":0.0626687066231156,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11319 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,319 | train | mutant | 3,799,344 | 225 | 3,803,289 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191D | N191D | 1 | 1 | 0 | 0 | 191 | N | D | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,093,322 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.399806 | 0.059506 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179326,"numValue":-0.399806366510294,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179327,"numValue":0.0595061615013592,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11320 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,320 | train | mutant | 3,799,344 | 225 | 3,803,289 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191D | N191D | 1 | 1 | 0 | 0 | 191 | N | D | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,094,276 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.332325 | 0.100114 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181234,"numValue":-0.332325255701357,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181235,"numValue":0.10011387892512,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11321 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,321 | train | mutant | 3,799,345 | 225 | 3,803,290 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191E | N191E | 1 | 1 | 0 | 0 | 191 | N | E | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 3,852,595 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.497677 | 0.091073 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9697872,"numValue":0.497676906532078,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9697873,"numValue":0.0910729964209077,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11323 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,323 | train | mutant | 3,799,345 | 225 | 3,803,290 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191E | N191E | 1 | 1 | 0 | 0 | 191 | N | E | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,094,277 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.022818 | 0.13554 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181236,"numValue":-1.02281782984682,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181237,"numValue":0.135540035096176,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11324 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,324 | train | mutant | 3,799,346 | 225 | 3,803,291 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191F | N191F | 1 | 1 | 0 | 0 | 191 | N | F | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 3,852,596 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1.091984 | 0.209627 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9697874,"numValue":1.09198410238639,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9697875,"numValue":0.209626930154756,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11325 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,325 | train | mutant | 3,799,346 | 225 | 3,803,291 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191F | N191F | 1 | 1 | 0 | 0 | 191 | N | F | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,093,324 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.154722 | 0.162946 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179330,"numValue":-1.15472214201943,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179331,"numValue":0.162945966808501,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11326 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,326 | train | mutant | 3,799,346 | 225 | 3,803,291 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191F | N191F | 1 | 1 | 0 | 0 | 191 | N | F | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,094,278 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.134441 | 0.10681 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181238,"numValue":-1.13444139484134,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181239,"numValue":0.106810008623884,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11327 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,327 | train | mutant | 3,799,347 | 225 | 3,803,292 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191G | N191G | 1 | 1 | 0 | 0 | 191 | N | G | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 3,852,597 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.912803 | 0.153738 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9697876,"numValue":0.912802663607662,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9697877,"numValue":0.153737921066142,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11328 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,328 | train | mutant | 3,799,347 | 225 | 3,803,292 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191G | N191G | 1 | 1 | 0 | 0 | 191 | N | G | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,093,325 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.917406 | 0.039684 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179332,"numValue":-0.917405955793334,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179333,"numValue":0.0396841324691282,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11329 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,329 | train | mutant | 3,799,347 | 225 | 3,803,292 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191G | N191G | 1 | 1 | 0 | 0 | 191 | N | G | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,094,279 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.080256 | 0.093229 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181240,"numValue":-1.08025598333884,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181241,"numValue":0.0932293005391039,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11330 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,330 | train | mutant | 3,799,348 | 225 | 3,803,293 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191H | N191H | 1 | 1 | 0 | 0 | 191 | N | H | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 3,852,598 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.230079 | 0.176159 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9697878,"numValue":0.230078860544078,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9697879,"numValue":0.176159171322821,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11331 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,331 | train | mutant | 3,799,348 | 225 | 3,803,293 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191H | N191H | 1 | 1 | 0 | 0 | 191 | N | H | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,093,326 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.464789 | 0.096327 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179334,"numValue":-0.464789124000926,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179335,"numValue":0.0963271641327958,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11332 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,332 | train | mutant | 3,799,348 | 225 | 3,803,293 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191H | N191H | 1 | 1 | 0 | 0 | 191 | N | H | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,094,280 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.789945 | 0.151737 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181242,"numValue":-0.789944650196731,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181243,"numValue":0.151737196221948,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11333 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,333 | train | mutant | 3,799,349 | 225 | 3,803,294 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191I | N191I | 1 | 1 | 0 | 0 | 191 | N | I | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 3,852,599 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1.662021 | 0.776185 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9697880,"numValue":1.66202148198077,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9697881,"numValue":0.776185268381016,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11334 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,334 | train | mutant | 3,799,349 | 225 | 3,803,294 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191I | N191I | 1 | 1 | 0 | 0 | 191 | N | I | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,093,327 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.225117 | 0.209641 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179336,"numValue":-1.22511711973201,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179337,"numValue":0.209640552895669,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11335 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,335 | train | mutant | 3,799,349 | 225 | 3,803,294 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191I | N191I | 1 | 1 | 0 | 0 | 191 | N | I | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,094,281 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.025316 | 0.241885 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181244,"numValue":-1.02531642272726,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181245,"numValue":0.241884627199117,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11336 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,336 | train | mutant | 3,799,350 | 225 | 3,803,295 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191K | N191K | 1 | 1 | 0 | 0 | 191 | N | K | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 3,852,600 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.847987 | 0.098092 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9697882,"numValue":0.847987129634333,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9697883,"numValue":0.0980918938233722,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11337 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,337 | train | mutant | 3,799,350 | 225 | 3,803,295 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191K | N191K | 1 | 1 | 0 | 0 | 191 | N | K | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,093,328 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.81165 | 0.104025 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179338,"numValue":-0.811650138525019,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179339,"numValue":0.104025423910113,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11338 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,338 | train | mutant | 3,799,350 | 225 | 3,803,295 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191K | N191K | 1 | 1 | 0 | 0 | 191 | N | K | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,094,282 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.765629 | 0.104534 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181246,"numValue":-0.765629099779948,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181247,"numValue":0.10453402474181,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11339 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,339 | train | mutant | 3,799,351 | 225 | 3,803,296 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191L | N191L | 1 | 1 | 0 | 0 | 191 | N | L | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 3,852,601 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1.256052 | 0.329313 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9697884,"numValue":1.2560524146894,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9697885,"numValue":0.329312992973768,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11340 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,340 | train | mutant | 3,799,351 | 225 | 3,803,296 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191L | N191L | 1 | 1 | 0 | 0 | 191 | N | L | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,093,329 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.165901 | 0.101768 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179340,"numValue":-1.16590062380169,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179341,"numValue":0.101767594531032,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11341 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,341 | train | mutant | 3,799,351 | 225 | 3,803,296 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191L | N191L | 1 | 1 | 0 | 0 | 191 | N | L | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,094,283 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.235427 | 0.106326 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181248,"numValue":-1.23542739643131,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181249,"numValue":0.106325811019028,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11342 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,342 | train | mutant | 3,799,352 | 225 | 3,803,297 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191M | N191M | 1 | 1 | 0 | 0 | 191 | N | M | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 3,852,602 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.900615 | 0.125662 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9697886,"numValue":0.900614749133752,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9697887,"numValue":0.125662439483224,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11343 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,343 | train | mutant | 3,799,352 | 225 | 3,803,297 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191M | N191M | 1 | 1 | 0 | 0 | 191 | N | M | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,093,330 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.162216 | 0.053544 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179342,"numValue":-1.16221640378674,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179343,"numValue":0.0535435310069941,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11344 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,344 | train | mutant | 3,799,352 | 225 | 3,803,297 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191M | N191M | 1 | 1 | 0 | 0 | 191 | N | M | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,094,284 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.128015 | 0.166299 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181250,"numValue":-1.12801544343725,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181251,"numValue":0.166299410839169,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11346 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,346 | train | mutant | 3,799,353 | 225 | 3,803,298 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191P | N191P | 1 | 1 | 0 | 0 | 191 | N | P | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,093,731 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.969696 | 0.11921 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180144,"numValue":-0.969695874429239,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180145,"numValue":0.119210258363008,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11347 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,347 | train | mutant | 3,799,353 | 225 | 3,803,298 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191P | N191P | 1 | 1 | 0 | 0 | 191 | N | P | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,094,665 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.974016 | 0.167703 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182012,"numValue":-0.974016281817747,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182013,"numValue":0.167703243707579,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11348 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,348 | train | mutant | 3,799,354 | 225 | 3,803,299 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191Q | N191Q | 1 | 1 | 0 | 0 | 191 | N | Q | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 3,852,604 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.487953 | 0.095428 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9697890,"numValue":0.487953300367847,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9697891,"numValue":0.0954278437012305,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11349 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,349 | train | mutant | 3,799,354 | 225 | 3,803,299 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191Q | N191Q | 1 | 1 | 0 | 0 | 191 | N | Q | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,093,732 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.970451 | 0.182612 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180146,"numValue":-0.970450949893201,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180147,"numValue":0.182612085665937,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11351 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,351 | train | mutant | 3,799,355 | 225 | 3,803,300 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191R | N191R | 1 | 1 | 0 | 0 | 191 | N | R | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 3,852,605 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.788268 | 0.089076 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9697892,"numValue":0.78826835171169,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9697893,"numValue":0.0890755265333779,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11352 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,352 | train | mutant | 3,799,355 | 225 | 3,803,300 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191R | N191R | 1 | 1 | 0 | 0 | 191 | N | R | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,093,733 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.586444 | 0.044628 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180148,"numValue":-0.586443877536739,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180149,"numValue":0.0446281435364518,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11353 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,353 | train | mutant | 3,799,355 | 225 | 3,803,300 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191R | N191R | 1 | 1 | 0 | 0 | 191 | N | R | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,094,667 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.618462 | 0.042053 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182016,"numValue":-0.618462298045986,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182017,"numValue":0.042052526545689,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11354 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,354 | train | mutant | 3,799,356 | 225 | 3,803,301 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191S | N191S | 1 | 1 | 0 | 0 | 191 | N | S | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 3,852,606 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.352675 | 0.060561 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9697894,"numValue":0.352674955329229,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9697895,"numValue":0.0605605823554103,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11355 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,355 | train | mutant | 3,799,356 | 225 | 3,803,301 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191S | N191S | 1 | 1 | 0 | 0 | 191 | N | S | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,093,734 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.393186 | 0.03834 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180150,"numValue":-0.393186040049951,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180151,"numValue":0.0383398341714463,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11356 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,356 | train | mutant | 3,799,356 | 225 | 3,803,301 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191S | N191S | 1 | 1 | 0 | 0 | 191 | N | S | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,094,668 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.409874 | 0.056026 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182018,"numValue":-0.409874122974321,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182019,"numValue":0.056026064033893,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11357 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,357 | train | mutant | 3,799,357 | 225 | 3,803,302 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191T | N191T | 1 | 1 | 0 | 0 | 191 | N | T | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 3,852,607 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.927459 | 0.139223 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9697896,"numValue":0.927458656081353,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9697897,"numValue":0.139222689946115,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11359 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,359 | train | mutant | 3,799,357 | 225 | 3,803,302 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191T | N191T | 1 | 1 | 0 | 0 | 191 | N | T | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,094,669 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.911623 | 0.049294 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182020,"numValue":-0.911623465773698,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182021,"numValue":0.0492939384388316,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11360 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,360 | train | mutant | 3,799,358 | 225 | 3,803,303 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191V | N191V | 1 | 1 | 0 | 0 | 191 | N | V | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 3,852,608 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1.436154 | 0.143639 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9697898,"numValue":1.43615391666739,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9697899,"numValue":0.143639067571137,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11362 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,362 | train | mutant | 3,799,358 | 225 | 3,803,303 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191V | N191V | 1 | 1 | 0 | 0 | 191 | N | V | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,094,670 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.15451 | 0.155808 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182022,"numValue":-1.15450974133185,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182023,"numValue":0.15580780126183,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11363 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,363 | train | mutant | 3,799,359 | 225 | 3,803,304 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191W | N191W | 1 | 1 | 0 | 0 | 191 | N | W | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 3,852,609 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1.005875 | 0.170015 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9697900,"numValue":1.00587518692909,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9697901,"numValue":0.170015037822696,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11365 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,365 | train | mutant | 3,799,359 | 225 | 3,803,304 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191W | N191W | 1 | 1 | 0 | 0 | 191 | N | W | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,094,671 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.066684 | 0.068998 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182024,"numValue":-1.06668448861598,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182025,"numValue":0.0689984067439541,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11366 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,366 | train | mutant | 3,799,360 | 225 | 3,803,305 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191Y | N191Y | 1 | 1 | 0 | 0 | 191 | N | Y | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 3,852,610 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.77629 | 0.20441 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9697902,"numValue":0.776290144535477,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9697903,"numValue":0.204409937869048,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11367 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,367 | train | mutant | 3,799,360 | 225 | 3,803,305 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N191Y | N191Y | 1 | 1 | 0 | 0 | 191 | N | Y | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,093,738 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.609873 | 0.141983 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180158,"numValue":-0.60987348047771,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180159,"numValue":0.141982687480082,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11369 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,369 | train | mutant | 4,905,678 | 225 | 4,912,266 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delN191 | delN191 | 1 | 0 | 1 | 0 | 191 | N | - | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,093,319 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.319217 | 0.171827 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179320,"numValue":-1.31921653567113,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179321,"numValue":0.171826588318861,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11370 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,370 | train | mutant | 4,905,678 | 225 | 4,912,266 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delN191 | delN191 | 1 | 0 | 1 | 0 | 191 | N | - | 9 | CONSERVATION | 1K9Q | 347 | null | 191 | A | E | false | false | 15.465568 | null | 5,094,273 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.113343 | 0.249514 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181228,"numValue":-1.1133431504067,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181229,"numValue":0.249514424820358,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16855,"numValue":9.0,"position":191,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11371 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,371 | train | mutant | 3,800,651 | 225 | 3,804,596 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192A | H192A | 1 | 1 | 0 | 0 | 192 | H | A | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 3,853,903 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.098509 | 0.050002 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9700488,"numValue":0.0985085177228109,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9700489,"numValue":0.0500016983860507,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11372 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,372 | train | mutant | 3,800,651 | 225 | 3,804,596 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192A | H192A | 1 | 1 | 0 | 0 | 192 | H | A | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,093,332 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.238012 | 0.046933 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179346,"numValue":-0.238011940548149,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179347,"numValue":0.0469332340257774,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11373 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,373 | train | mutant | 3,800,651 | 225 | 3,804,596 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192A | H192A | 1 | 1 | 0 | 0 | 192 | H | A | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,094,286 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.215546 | 0.061723 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181254,"numValue":-0.215545893376916,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181255,"numValue":0.0617228274524946,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11374 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,374 | train | mutant | 3,800,652 | 225 | 3,804,597 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192C | H192C | 1 | 1 | 0 | 0 | 192 | H | C | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 3,853,904 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.130862 | 0.063402 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9700490,"numValue":0.130862327503398,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9700491,"numValue":0.0634017786550185,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11375 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,375 | train | mutant | 3,800,652 | 225 | 3,804,597 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192C | H192C | 1 | 1 | 0 | 0 | 192 | H | C | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,093,333 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.296933 | 0.077494 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179348,"numValue":-0.29693277352547,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179349,"numValue":0.0774941519724403,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11376 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,376 | train | mutant | 3,800,652 | 225 | 3,804,597 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192C | H192C | 1 | 1 | 0 | 0 | 192 | H | C | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,094,287 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.476181 | 0.124625 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181256,"numValue":-0.476180562545554,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181257,"numValue":0.124624894358618,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11377 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,377 | train | mutant | 3,800,653 | 225 | 3,804,598 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192D | H192D | 1 | 1 | 0 | 0 | 192 | H | D | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 3,853,905 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.282842 | 0.069791 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9700492,"numValue":0.282841817544537,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9700493,"numValue":0.0697914123790326,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11378 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,378 | train | mutant | 3,800,653 | 225 | 3,804,598 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192D | H192D | 1 | 1 | 0 | 0 | 192 | H | D | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,093,334 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.539901 | 0.072463 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179350,"numValue":-0.53990071265287,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179351,"numValue":0.0724633420362331,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11379 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,379 | train | mutant | 3,800,653 | 225 | 3,804,598 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192D | H192D | 1 | 1 | 0 | 0 | 192 | H | D | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,094,288 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.632227 | 0.13168 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181258,"numValue":-0.632226848137059,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181259,"numValue":0.131680203428196,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11380 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,380 | train | mutant | 3,800,654 | 225 | 3,804,599 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192E | H192E | 1 | 1 | 0 | 0 | 192 | H | E | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 3,853,906 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.14464 | 0.128331 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9700494,"numValue":0.144639588335257,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9700495,"numValue":0.12833105374359,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11381 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,381 | train | mutant | 3,800,654 | 225 | 3,804,599 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192E | H192E | 1 | 1 | 0 | 0 | 192 | H | E | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,093,335 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.444399 | 0.055767 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179352,"numValue":-0.44439947576355,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179353,"numValue":0.055767290615333,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11382 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,382 | train | mutant | 3,800,654 | 225 | 3,804,599 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192E | H192E | 1 | 1 | 0 | 0 | 192 | H | E | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,094,289 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.693048 | 0.094255 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181260,"numValue":-0.6930482898698,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181261,"numValue":0.094254889464728,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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