row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:11383 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,383 | train | mutant | 3,800,655 | 225 | 3,804,600 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192F | H192F | 1 | 1 | 0 | 0 | 192 | H | F | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 3,853,907 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.330814 | 0.088798 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9700496,"numValue":0.330813959791252,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9700497,"numValue":0.0887979873194692,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11384 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,384 | train | mutant | 3,800,655 | 225 | 3,804,600 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192F | H192F | 1 | 1 | 0 | 0 | 192 | H | F | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,093,336 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.77367 | 0.15639 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179354,"numValue":-0.773669523600902,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179355,"numValue":0.1563900378714,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11385 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,385 | train | mutant | 3,800,655 | 225 | 3,804,600 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192F | H192F | 1 | 1 | 0 | 0 | 192 | H | F | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,094,290 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.510084 | 0.098908 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181262,"numValue":-0.510083962607429,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181263,"numValue":0.0989082750820003,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11386 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,386 | train | mutant | 3,800,656 | 225 | 3,804,601 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192G | H192G | 1 | 1 | 0 | 0 | 192 | H | G | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 3,853,908 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.198241 | 0.068991 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9700498,"numValue":0.198240676852516,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9700499,"numValue":0.0689905535324498,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11387 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,387 | train | mutant | 3,800,656 | 225 | 3,804,601 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192G | H192G | 1 | 1 | 0 | 0 | 192 | H | G | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,093,337 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.435134 | 0.034564 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179356,"numValue":-0.435134354626805,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179357,"numValue":0.0345640797490225,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11388 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,388 | train | mutant | 3,800,656 | 225 | 3,804,601 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192G | H192G | 1 | 1 | 0 | 0 | 192 | H | G | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,094,291 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.460037 | 0.03809 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181264,"numValue":-0.460037335023017,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181265,"numValue":0.0380901855955571,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11389 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,389 | train | mutant | 3,800,657 | 225 | 3,804,602 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192I | H192I | 1 | 1 | 0 | 0 | 192 | H | I | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 3,853,909 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.052933 | 0.071105 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9700500,"numValue":0.0529326436926478,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9700501,"numValue":0.0711045856137548,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11390 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,390 | train | mutant | 3,800,657 | 225 | 3,804,602 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192I | H192I | 1 | 1 | 0 | 0 | 192 | H | I | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,093,718 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.369465 | 0.069022 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180118,"numValue":-0.369464835261055,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180119,"numValue":0.0690219108366687,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11391 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,391 | train | mutant | 3,800,657 | 225 | 3,804,602 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192I | H192I | 1 | 1 | 0 | 0 | 192 | H | I | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,094,652 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.576231 | 0.121253 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181986,"numValue":-0.576231365377536,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181987,"numValue":0.121253016512276,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11392 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,392 | train | mutant | 3,800,658 | 225 | 3,804,603 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192K | H192K | 1 | 1 | 0 | 0 | 192 | H | K | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 3,853,910 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.075479 | 0.071023 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9700502,"numValue":-0.0754788844950006,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9700503,"numValue":0.0710230320255744,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11393 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,393 | train | mutant | 3,800,658 | 225 | 3,804,603 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192K | H192K | 1 | 1 | 0 | 0 | 192 | H | K | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,093,719 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.015745 | 0.062785 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180120,"numValue":0.0157447593143293,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180121,"numValue":0.0627847786475102,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11394 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,394 | train | mutant | 3,800,658 | 225 | 3,804,603 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192K | H192K | 1 | 1 | 0 | 0 | 192 | H | K | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,094,653 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.163593 | 0.056724 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181988,"numValue":-0.163593162955474,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181989,"numValue":0.0567242809489274,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11395 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,395 | train | mutant | 3,800,659 | 225 | 3,804,604 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192L | H192L | 1 | 1 | 0 | 0 | 192 | H | L | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 3,853,911 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.092237 | 0.070011 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9700504,"numValue":0.0922367616456254,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9700505,"numValue":0.0700112697079877,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11396 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,396 | train | mutant | 3,800,659 | 225 | 3,804,604 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192L | H192L | 1 | 1 | 0 | 0 | 192 | H | L | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,093,720 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.211937 | 0.050797 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180122,"numValue":-0.211937470411042,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180123,"numValue":0.0507968316012454,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11397 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,397 | train | mutant | 3,800,659 | 225 | 3,804,604 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192L | H192L | 1 | 1 | 0 | 0 | 192 | H | L | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,094,654 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.300762 | 0.04877 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181990,"numValue":-0.300761695206857,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181991,"numValue":0.0487701871625374,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11398 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,398 | train | mutant | 3,800,660 | 225 | 3,804,605 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192M | H192M | 1 | 1 | 0 | 0 | 192 | H | M | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 3,853,912 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.0331 | 0.079543 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9700506,"numValue":0.0331002241745806,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9700507,"numValue":0.0795426329298562,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11399 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,399 | train | mutant | 3,800,660 | 225 | 3,804,605 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192M | H192M | 1 | 1 | 0 | 0 | 192 | H | M | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,093,721 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.315901 | 0.054868 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180124,"numValue":-0.315901034988581,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180125,"numValue":0.0548684085200766,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11401 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,401 | train | mutant | 3,800,661 | 225 | 3,804,606 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192N | H192N | 1 | 1 | 0 | 0 | 192 | H | N | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 3,853,913 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.020378 | 0.140368 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9700508,"numValue":0.020378234635761,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9700509,"numValue":0.140367764259614,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11402 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,402 | train | mutant | 3,800,661 | 225 | 3,804,606 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192N | H192N | 1 | 1 | 0 | 0 | 192 | H | N | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,093,722 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.398497 | 0.112193 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180126,"numValue":-0.398496660125435,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180127,"numValue":0.112193031401871,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11403 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,403 | train | mutant | 3,800,661 | 225 | 3,804,606 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192N | H192N | 1 | 1 | 0 | 0 | 192 | H | N | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,094,656 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.202234 | 0.040175 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181994,"numValue":-0.202234002844129,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181995,"numValue":0.0401753607522866,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11404 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,404 | train | mutant | 3,800,662 | 225 | 3,804,607 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192P | H192P | 1 | 1 | 0 | 0 | 192 | H | P | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 3,853,914 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.233437 | 0.049113 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9700510,"numValue":0.233436697935837,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9700511,"numValue":0.0491128077107163,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11405 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,405 | train | mutant | 3,800,662 | 225 | 3,804,607 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192P | H192P | 1 | 1 | 0 | 0 | 192 | H | P | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,093,723 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.454926 | 0.064356 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180128,"numValue":-0.454925715063789,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180129,"numValue":0.0643564408132879,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11406 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,406 | train | mutant | 3,800,662 | 225 | 3,804,607 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192P | H192P | 1 | 1 | 0 | 0 | 192 | H | P | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,094,657 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.453038 | 0.064523 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181996,"numValue":-0.4530380148451,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181997,"numValue":0.0645229027965335,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11407 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,407 | train | mutant | 3,800,663 | 225 | 3,804,608 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192Q | H192Q | 1 | 1 | 0 | 0 | 192 | H | Q | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 3,853,915 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.099128 | 0.083324 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9700512,"numValue":0.0991280747305706,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9700513,"numValue":0.0833244423035505,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11408 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,408 | train | mutant | 3,800,663 | 225 | 3,804,608 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192Q | H192Q | 1 | 1 | 0 | 0 | 192 | H | Q | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,093,724 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.292247 | 0.07381 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180130,"numValue":-0.292246548354396,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180131,"numValue":0.0738102945561568,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11409 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,409 | train | mutant | 3,800,663 | 225 | 3,804,608 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192Q | H192Q | 1 | 1 | 0 | 0 | 192 | H | Q | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,094,658 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.310658 | 0.072262 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181998,"numValue":-0.310657554628105,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181999,"numValue":0.072261673227673,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11411 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,411 | train | mutant | 3,800,664 | 225 | 3,804,609 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192R | H192R | 1 | 1 | 0 | 0 | 192 | H | R | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,093,725 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.200518 | 0.03777 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180132,"numValue":-0.20051778799555,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180133,"numValue":0.0377698145631257,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11412 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,412 | train | mutant | 3,800,664 | 225 | 3,804,609 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192R | H192R | 1 | 1 | 0 | 0 | 192 | H | R | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,094,659 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.222776 | 0.035815 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182000,"numValue":-0.222776256322958,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182001,"numValue":0.0358150805264664,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11413 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,413 | train | mutant | 3,800,665 | 225 | 3,804,610 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192S | H192S | 1 | 1 | 0 | 0 | 192 | H | S | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 3,853,917 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.048827 | 0.071268 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9700516,"numValue":0.0488266038359777,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9700517,"numValue":0.0712682644326743,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11414 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,414 | train | mutant | 3,800,665 | 225 | 3,804,610 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192S | H192S | 1 | 1 | 0 | 0 | 192 | H | S | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,093,726 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.183913 | 0.038877 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180134,"numValue":-0.183912944643323,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180135,"numValue":0.0388765237103051,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11415 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,415 | train | mutant | 3,800,665 | 225 | 3,804,610 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192S | H192S | 1 | 1 | 0 | 0 | 192 | H | S | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,094,660 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.36932 | 0.042467 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182002,"numValue":-0.369319738687086,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182003,"numValue":0.0424672908376819,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11416 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,416 | train | mutant | 3,800,666 | 225 | 3,804,611 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192T | H192T | 1 | 1 | 0 | 0 | 192 | H | T | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 3,853,918 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.011047 | 0.079487 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9700518,"numValue":0.0110468214032705,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9700519,"numValue":0.0794874649218239,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11417 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,417 | train | mutant | 3,800,666 | 225 | 3,804,611 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192T | H192T | 1 | 1 | 0 | 0 | 192 | H | T | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,093,727 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.171236 | 0.047798 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180136,"numValue":-0.171235770051006,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180137,"numValue":0.047798401696985,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11418 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,418 | train | mutant | 3,800,666 | 225 | 3,804,611 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192T | H192T | 1 | 1 | 0 | 0 | 192 | H | T | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,094,661 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.181022 | 0.06963 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182004,"numValue":-0.181022008825798,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182005,"numValue":0.0696299685291047,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11419 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,419 | train | mutant | 3,800,667 | 225 | 3,804,612 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192V | H192V | 1 | 1 | 0 | 0 | 192 | H | V | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 3,853,919 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.095983 | 0.063398 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9700520,"numValue":0.0959825372830734,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9700521,"numValue":0.0633975284700894,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11420 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,420 | train | mutant | 3,800,667 | 225 | 3,804,612 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192V | H192V | 1 | 1 | 0 | 0 | 192 | H | V | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,093,728 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.24178 | 0.051506 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180138,"numValue":-0.241780065894621,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180139,"numValue":0.0515064589482977,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11421 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,421 | train | mutant | 3,800,667 | 225 | 3,804,612 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192V | H192V | 1 | 1 | 0 | 0 | 192 | H | V | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,094,662 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.221266 | 0.037899 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182006,"numValue":-0.221265973688375,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182007,"numValue":0.0378992280389818,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11422 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,422 | train | mutant | 3,800,668 | 225 | 3,804,613 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192W | H192W | 1 | 1 | 0 | 0 | 192 | H | W | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 3,853,920 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.272263 | 0.074924 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9700522,"numValue":0.272262604255365,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9700523,"numValue":0.0749239478525422,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11424 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,424 | train | mutant | 3,800,668 | 225 | 3,804,613 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192W | H192W | 1 | 1 | 0 | 0 | 192 | H | W | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,094,663 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.542159 | 0.067505 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182008,"numValue":-0.542158935560453,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182009,"numValue":0.0675047932072434,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11426 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,426 | train | mutant | 3,800,669 | 225 | 3,804,614 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192Y | H192Y | 1 | 1 | 0 | 0 | 192 | H | Y | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,093,730 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.381104 | 0.077549 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180142,"numValue":-0.381103527271358,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180143,"numValue":0.0775490494106096,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11427 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,427 | train | mutant | 3,800,669 | 225 | 3,804,614 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | H192Y | H192Y | 1 | 1 | 0 | 0 | 192 | H | Y | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,094,664 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.36876 | 0.052749 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182010,"numValue":-0.368759849770464,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182011,"numValue":0.0527491759489369,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11429 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,429 | train | mutant | 4,905,679 | 225 | 4,912,267 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delH192 | delH192 | 1 | 0 | 1 | 0 | 192 | H | - | 9 | CONSERVATION | 1K9Q | 347 | null | 192 | A | T | false | false | 90.931641 | null | 5,094,285 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.390145 | 0.245935 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181252,"numValue":-1.39014542707095,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181253,"numValue":0.245934537610689,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16856,"numValue":9.0,"position":192,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11430 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,430 | train | mutant | 3,801,960 | 225 | 3,805,905 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193A | I193A | 1 | 1 | 0 | 0 | 193 | I | A | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 3,855,214 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.034945 | 0.101075 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9703110,"numValue":-0.0349454976067115,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9703111,"numValue":0.101075215316765,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11431 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,431 | train | mutant | 3,801,960 | 225 | 3,805,905 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193A | I193A | 1 | 1 | 0 | 0 | 193 | I | A | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,093,339 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.527773 | 0.190928 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179360,"numValue":-0.527772512442247,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179361,"numValue":0.190928358611126,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11432 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,432 | train | mutant | 3,801,960 | 225 | 3,805,905 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193A | I193A | 1 | 1 | 0 | 0 | 193 | I | A | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,094,293 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.01615 | 0.033561 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181268,"numValue":-0.0161503147240136,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181269,"numValue":0.0335612228874014,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11433 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,433 | train | mutant | 3,801,961 | 225 | 3,805,906 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193C | I193C | 1 | 1 | 0 | 0 | 193 | I | C | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 3,855,215 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.104649 | 0.078519 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9703112,"numValue":0.104648836521609,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9703113,"numValue":0.0785193814970651,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11434 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,434 | train | mutant | 3,801,961 | 225 | 3,805,906 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193C | I193C | 1 | 1 | 0 | 0 | 193 | I | C | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,093,340 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.085434 | 0.11643 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179362,"numValue":-0.0854340475013827,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179363,"numValue":0.116430431943051,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11435 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,435 | train | mutant | 3,801,961 | 225 | 3,805,906 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193C | I193C | 1 | 1 | 0 | 0 | 193 | I | C | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,094,294 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.266404 | 0.0744 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181270,"numValue":-0.26640435989043,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181271,"numValue":0.0743998110410342,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11436 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,436 | train | mutant | 3,801,962 | 225 | 3,805,907 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193D | I193D | 1 | 1 | 0 | 0 | 193 | I | D | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 3,855,216 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.033197 | 0.081263 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9703114,"numValue":0.0331972976331723,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9703115,"numValue":0.0812631982617511,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11437 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,437 | train | mutant | 3,801,962 | 225 | 3,805,907 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193D | I193D | 1 | 1 | 0 | 0 | 193 | I | D | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,093,341 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.072853 | 0.193448 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179364,"numValue":0.0728525989571285,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179365,"numValue":0.193447694148779,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11438 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,438 | train | mutant | 3,801,962 | 225 | 3,805,907 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193D | I193D | 1 | 1 | 0 | 0 | 193 | I | D | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,094,295 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.075231 | 0.07755 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181272,"numValue":-0.0752313523902392,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181273,"numValue":0.0775504973293033,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11439 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,439 | train | mutant | 3,801,963 | 225 | 3,805,908 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193E | I193E | 1 | 1 | 0 | 0 | 193 | I | E | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 3,855,217 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.009612 | 0.070364 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9703116,"numValue":-0.00961154846880623,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9703117,"numValue":0.070363865139735,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11440 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,440 | train | mutant | 3,801,963 | 225 | 3,805,908 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193E | I193E | 1 | 1 | 0 | 0 | 193 | I | E | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,093,342 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.221035 | 0.132905 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179366,"numValue":0.221035070963677,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179367,"numValue":0.132905464972526,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11441 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,441 | train | mutant | 3,801,963 | 225 | 3,805,908 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193E | I193E | 1 | 1 | 0 | 0 | 193 | I | E | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,094,296 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.043216 | 0.060678 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181274,"numValue":-0.0432156284415562,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181275,"numValue":0.0606784574429586,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11442 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,442 | train | mutant | 3,801,964 | 225 | 3,805,909 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193F | I193F | 1 | 1 | 0 | 0 | 193 | I | F | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 3,855,218 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.14597 | 0.057831 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9703118,"numValue":0.145969940104035,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9703119,"numValue":0.0578310679074968,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11443 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,443 | train | mutant | 3,801,964 | 225 | 3,805,909 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193F | I193F | 1 | 1 | 0 | 0 | 193 | I | F | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,093,343 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.896332 | 0.320408 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179368,"numValue":-0.896331793792575,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179369,"numValue":0.320408353977405,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11444 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,444 | train | mutant | 3,801,964 | 225 | 3,805,909 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193F | I193F | 1 | 1 | 0 | 0 | 193 | I | F | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,094,297 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.472403 | 0.10557 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181276,"numValue":-0.472403084158728,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181277,"numValue":0.105570457085693,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11445 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,445 | train | mutant | 3,801,965 | 225 | 3,805,910 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193G | I193G | 1 | 1 | 0 | 0 | 193 | I | G | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 3,855,219 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.012387 | 0.091038 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9703120,"numValue":0.0123873625881285,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9703121,"numValue":0.0910380159473285,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11446 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,446 | train | mutant | 3,801,965 | 225 | 3,805,910 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193G | I193G | 1 | 1 | 0 | 0 | 193 | I | G | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,093,344 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.355582 | 0.104404 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179370,"numValue":-0.355582382699948,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179371,"numValue":0.104404484556495,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11447 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,447 | train | mutant | 3,801,965 | 225 | 3,805,910 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193G | I193G | 1 | 1 | 0 | 0 | 193 | I | G | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,094,298 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.033633 | 0.041329 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181278,"numValue":-0.0336330233255569,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181279,"numValue":0.0413290650189963,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11448 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,448 | train | mutant | 3,801,966 | 225 | 3,805,911 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193H | I193H | 1 | 1 | 0 | 0 | 193 | I | H | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 3,855,220 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.023337 | 0.104336 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9703122,"numValue":-0.0233372208103089,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9703123,"numValue":0.104335805956717,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11449 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,449 | train | mutant | 3,801,966 | 225 | 3,805,911 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193H | I193H | 1 | 1 | 0 | 0 | 193 | I | H | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,093,345 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179372,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179373,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11450 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,450 | train | mutant | 3,801,966 | 225 | 3,805,911 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193H | I193H | 1 | 1 | 0 | 0 | 193 | I | H | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,094,299 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.108571 | 0.083991 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181280,"numValue":0.108570965574681,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181281,"numValue":0.0839910625428344,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11451 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,451 | train | mutant | 3,801,967 | 225 | 3,805,912 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193K | I193K | 1 | 1 | 0 | 0 | 193 | I | K | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 3,855,221 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.123927 | 0.067006 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9703124,"numValue":-0.123927155480724,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9703125,"numValue":0.0670060243721335,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11452 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,452 | train | mutant | 3,801,967 | 225 | 3,805,912 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193K | I193K | 1 | 1 | 0 | 0 | 193 | I | K | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,093,706 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180094,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180095,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11453 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,453 | train | mutant | 3,801,967 | 225 | 3,805,912 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193K | I193K | 1 | 1 | 0 | 0 | 193 | I | K | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,094,640 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.021956 | 0.044009 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181962,"numValue":-0.0219561501733343,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181963,"numValue":0.0440091540420427,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11454 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,454 | train | mutant | 3,801,968 | 225 | 3,805,913 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193L | I193L | 1 | 1 | 0 | 0 | 193 | I | L | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 3,855,222 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.023364 | 0.078087 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9703126,"numValue":0.0233635163680068,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9703127,"numValue":0.0780870531811923,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11455 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,455 | train | mutant | 3,801,968 | 225 | 3,805,913 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193L | I193L | 1 | 1 | 0 | 0 | 193 | I | L | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,093,707 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.052589 | 0.043793 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180096,"numValue":-0.0525891350558346,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180097,"numValue":0.0437930425467039,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11456 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,456 | train | mutant | 3,801,968 | 225 | 3,805,913 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193L | I193L | 1 | 1 | 0 | 0 | 193 | I | L | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,094,641 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.368934 | 0.03927 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181964,"numValue":-0.368934194926779,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181965,"numValue":0.0392704456061982,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11458 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,458 | train | mutant | 3,801,969 | 225 | 3,805,914 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193M | I193M | 1 | 1 | 0 | 0 | 193 | I | M | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,093,708 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.31976 | 0.686789 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180098,"numValue":-0.31975981000178,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180099,"numValue":0.686788852458037,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11459 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,459 | train | mutant | 3,801,969 | 225 | 3,805,914 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193M | I193M | 1 | 1 | 0 | 0 | 193 | I | M | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,094,642 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.156214 | 0.071097 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181966,"numValue":-0.156213968778432,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181967,"numValue":0.0710973168971445,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11460 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,460 | train | mutant | 3,801,970 | 225 | 3,805,915 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193N | I193N | 1 | 1 | 0 | 0 | 193 | I | N | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 3,855,224 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.01989 | 0.148791 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9703130,"numValue":-0.0198898302103896,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9703131,"numValue":0.148790591029951,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11461 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,461 | train | mutant | 3,801,970 | 225 | 3,805,915 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193N | I193N | 1 | 1 | 0 | 0 | 193 | I | N | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,093,709 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.7078 | 0.254575 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180100,"numValue":-0.707799994810488,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180101,"numValue":0.254574577415548,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11462 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,462 | train | mutant | 3,801,970 | 225 | 3,805,915 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193N | I193N | 1 | 1 | 0 | 0 | 193 | I | N | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,094,643 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.172489 | 0.080496 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181968,"numValue":0.172489018248428,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181969,"numValue":0.0804963634949095,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11463 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,463 | train | mutant | 3,801,971 | 225 | 3,805,916 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193P | I193P | 1 | 1 | 0 | 0 | 193 | I | P | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 3,855,225 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.245268 | 0.068147 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9703132,"numValue":0.245267774670035,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9703133,"numValue":0.0681469835343785,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11464 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,464 | train | mutant | 3,801,971 | 225 | 3,805,916 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193P | I193P | 1 | 1 | 0 | 0 | 193 | I | P | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,093,710 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.856828 | 0.644923 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180102,"numValue":-0.856827974388525,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180103,"numValue":0.64492284777857,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11465 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,465 | train | mutant | 3,801,971 | 225 | 3,805,916 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193P | I193P | 1 | 1 | 0 | 0 | 193 | I | P | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,094,644 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.348904 | 0.07001 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181970,"numValue":-0.348903637394534,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181971,"numValue":0.0700100409698715,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11466 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,466 | train | mutant | 3,801,972 | 225 | 3,805,917 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193Q | I193Q | 1 | 1 | 0 | 0 | 193 | I | Q | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 3,855,226 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.017682 | 0.065792 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9703134,"numValue":0.0176824122151085,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9703135,"numValue":0.065791883709575,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11467 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,467 | train | mutant | 3,801,972 | 225 | 3,805,917 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193Q | I193Q | 1 | 1 | 0 | 0 | 193 | I | Q | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,093,711 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180104,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180105,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11468 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,468 | train | mutant | 3,801,972 | 225 | 3,805,917 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193Q | I193Q | 1 | 1 | 0 | 0 | 193 | I | Q | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,094,645 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.340673 | 0.077942 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181972,"numValue":-0.34067256160005,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181973,"numValue":0.0779423486989236,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11469 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,469 | train | mutant | 3,801,973 | 225 | 3,805,918 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193R | I193R | 1 | 1 | 0 | 0 | 193 | I | R | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 3,855,227 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.042205 | 0.083108 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9703136,"numValue":-0.0422045107652638,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9703137,"numValue":0.0831083276579617,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11470 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,470 | train | mutant | 3,801,973 | 225 | 3,805,918 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193R | I193R | 1 | 1 | 0 | 0 | 193 | I | R | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,093,712 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.158971 | 0.110382 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180106,"numValue":-0.158971232741627,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180107,"numValue":0.110382141139617,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11471 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,471 | train | mutant | 3,801,973 | 225 | 3,805,918 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193R | I193R | 1 | 1 | 0 | 0 | 193 | I | R | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,094,646 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.07364 | 0.037218 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181974,"numValue":-0.0736402756588276,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181975,"numValue":0.0372181054539081,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11472 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,472 | train | mutant | 3,801,974 | 225 | 3,805,919 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193S | I193S | 1 | 1 | 0 | 0 | 193 | I | S | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 3,855,228 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.009729 | 0.095127 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9703138,"numValue":-0.00972883309274421,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9703139,"numValue":0.0951267748694057,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11473 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,473 | train | mutant | 3,801,974 | 225 | 3,805,919 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193S | I193S | 1 | 1 | 0 | 0 | 193 | I | S | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,093,713 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.198366 | 0.118773 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180108,"numValue":-0.198366127506139,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180109,"numValue":0.118772891850988,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11474 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,474 | train | mutant | 3,801,974 | 225 | 3,805,919 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193S | I193S | 1 | 1 | 0 | 0 | 193 | I | S | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,094,647 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.12865 | 0.037393 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181976,"numValue":-0.128650424797112,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181977,"numValue":0.0373933010744003,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11475 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,475 | train | mutant | 3,801,975 | 225 | 3,805,920 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193T | I193T | 1 | 1 | 0 | 0 | 193 | I | T | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 3,855,229 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.063391 | 0.0944 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9703140,"numValue":-0.0633910097194156,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9703141,"numValue":0.0943997918212835,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11476 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,476 | train | mutant | 3,801,975 | 225 | 3,805,920 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193T | I193T | 1 | 1 | 0 | 0 | 193 | I | T | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,093,714 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.19603 | 0.18258 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180110,"numValue":-0.196029541696606,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180111,"numValue":0.182579596825382,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11477 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,477 | train | mutant | 3,801,975 | 225 | 3,805,920 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193T | I193T | 1 | 1 | 0 | 0 | 193 | I | T | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,094,648 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.089973 | 0.072778 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181978,"numValue":-0.0899734401809277,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181979,"numValue":0.0727784719593191,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11479 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,479 | train | mutant | 3,801,976 | 225 | 3,805,921 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193V | I193V | 1 | 1 | 0 | 0 | 193 | I | V | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,093,715 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.127576 | 0.090761 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180112,"numValue":-0.127575989766363,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180113,"numValue":0.0907612020760775,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11480 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,480 | train | mutant | 3,801,976 | 225 | 3,805,921 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193V | I193V | 1 | 1 | 0 | 0 | 193 | I | V | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,094,649 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.020521 | 0.03616 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181980,"numValue":-0.0205209918743995,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181981,"numValue":0.0361604682032086,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11482 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,482 | train | mutant | 3,801,977 | 225 | 3,805,922 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193W | I193W | 1 | 1 | 0 | 0 | 193 | I | W | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,093,716 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.638471 | 0.186944 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180114,"numValue":-0.638471419777271,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180115,"numValue":0.186943544301312,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11484 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,484 | train | mutant | 3,801,978 | 225 | 3,805,923 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193Y | I193Y | 1 | 1 | 0 | 0 | 193 | I | Y | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 3,855,232 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.1594 | 0.081328 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9703146,"numValue":0.159399781795033,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9703147,"numValue":0.0813283137505284,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11485 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,485 | train | mutant | 3,801,978 | 225 | 3,805,923 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | I193Y | I193Y | 1 | 1 | 0 | 0 | 193 | I | Y | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,093,717 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.296059 | 0.113209 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12180116,"numValue":0.29605891073823,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12180117,"numValue":0.113208960346804,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11487 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,487 | train | mutant | 4,905,680 | 225 | 4,912,268 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delI193 | delI193 | 1 | 0 | 1 | 0 | 193 | I | - | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,093,338 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12179358,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12179359,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11488 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,488 | train | mutant | 4,905,680 | 225 | 4,912,268 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delI193 | delI193 | 1 | 0 | 1 | 0 | 193 | I | - | 4 | CONSERVATION | 1K9Q | 347 | null | 193 | A | T | false | false | 138.352747 | null | 5,094,292 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.2005 | 0.189567 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181266,"numValue":-1.20049994253166,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181267,"numValue":0.18956662241359,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16857,"numValue":4.0,"position":193,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11489 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,489 | train | mutant | 198 | 225 | 227 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D194T | D194T | 1 | 1 | 0 | 0 | 194 | D | T | 6 | CONSERVATION | 1K9Q | 347 | null | 194 | A | T | false | false | 90.782416 | null | 373 | ProTherm | 7 | Fluorescence | Thermal | potassium phosphate | 20 mM | null | NaCl | 100 mM | 1K9Q_A:D34T | 56.5 | 4.9 | null | null | null | null | 29.2 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 39 | ARTICLE | Increasing protein stability using a rational approach combining sequence homology and structural alignment: Stabilizing the WW domain. | 2,001 | 10.1110/ps.640101 | 11420447 | Protein Sci;10;1454-65 | 3 | Jiang X|Kowalski J|Kelly J W | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"potassium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"20 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl... | [{"datasets":[],"id":1535,"numValue":56.5,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":1536,"numValue":4.9,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":1537,"numValue":29.2,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":1538,"numValue":null,"references":[],"s... | [{"id":16858,"numValue":6.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||
fireprotdb:11490 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,490 | train | mutant | 198 | 225 | 227 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D194T | D194T | 1 | 1 | 0 | 0 | 194 | D | T | 6 | CONSERVATION | 1K9Q | 347 | null | 194 | A | T | false | false | 90.782416 | null | 376 | ProTherm | 7 | Fluorescence | Thermal | potassium | 20 mM | null | NaCl | 2 M | 1K9Q_A:D34T | 57.7 | 4.8 | null | null | null | null | 24.7 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 39 | ARTICLE | Increasing protein stability using a rational approach combining sequence homology and structural alignment: Stabilizing the WW domain. | 2,001 | 10.1110/ps.640101 | 11420447 | Protein Sci;10;1454-65 | 3 | Jiang X|Kowalski J|Kelly J W | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"potassium","type":"BUFFER"},{"numValue":null,"strValue":"20 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"... | [{"datasets":[],"id":1547,"numValue":57.7,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":1548,"numValue":4.8,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":1549,"numValue":24.7,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":1550,"numValue":null,"references":[],"s... | [{"id":16858,"numValue":6.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||
fireprotdb:11491 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,491 | train | mutant | 198 | 225 | 227 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D194T | D194T | 1 | 1 | 0 | 0 | 194 | D | T | 6 | CONSERVATION | 1K9Q | 347 | null | 194 | A | T | false | false | 90.782416 | null | 3,856,540 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.180886 | 0.143658 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9705762,"numValue":-0.180886486490769,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9705763,"numValue":0.143657758482356,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16858,"numValue":6.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:11493 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 11,493 | train | mutant | 198 | 225 | 227 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D194T | D194T | 1 | 1 | 0 | 0 | 194 | D | T | 6 | CONSERVATION | 1K9Q | 347 | null | 194 | A | T | false | false | 90.782416 | null | 5,094,636 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.035403 | 0.069737 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12181954,"numValue":-0.0354034062543172,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12181955,"numValue":0.0697373892418797,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16858,"numValue":6.0,"position":194,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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