row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:15961 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,961 | train | mutant | 305 | 336 | 339 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T68W | T68W | 1 | 1 | 0 | 0 | 68 | T | W | 4 | CONSERVATION | 1MJC | 50 | null | 68 | A | E | false | false | 46.382902 | 27.085715 | 5,003,082 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.101235 | 0.032218 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998846,"numValue":-0.101235189594642,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998847,"numValue":0.0322184990326712,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20740,"numValue":4.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15962 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,962 | train | mutant | 4,873,906 | 336 | 4,880,480 | 70 | 69 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delT68 | delT68 | 1 | 0 | 1 | 0 | 68 | T | - | 4 | CONSERVATION | 1MJC | 50 | null | 68 | A | E | false | false | 46.382902 | 27.085715 | 5,003,025 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.919602 | 0.089066 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998732,"numValue":-0.919602472335915,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998733,"numValue":0.0890659359919969,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20740,"numValue":4.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15963 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,963 | train | mutant | 4,873,907 | 336 | 4,880,481 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T68A | T68A | 1 | 1 | 0 | 0 | 68 | T | A | 4 | CONSERVATION | 1MJC | 50 | null | 68 | A | E | false | false | 46.382902 | 27.085715 | 5,003,026 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.067438 | 0.037981 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998734,"numValue":-0.067437713059884,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998735,"numValue":0.037981471739289,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20740,"numValue":4.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15964 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,964 | train | mutant | 4,873,908 | 336 | 4,880,482 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T68C | T68C | 1 | 1 | 0 | 0 | 68 | T | C | 4 | CONSERVATION | 1MJC | 50 | null | 68 | A | E | false | false | 46.382902 | 27.085715 | 5,003,027 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.043099 | 0.040592 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998736,"numValue":-0.0430985038902644,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998737,"numValue":0.0405922736278012,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20740,"numValue":4.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15965 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,965 | train | mutant | 4,873,909 | 336 | 4,880,483 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T68D | T68D | 1 | 1 | 0 | 0 | 68 | T | D | 4 | CONSERVATION | 1MJC | 50 | null | 68 | A | E | false | false | 46.382902 | 27.085715 | 5,003,028 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.182853 | 0.057279 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998738,"numValue":-0.182852582094619,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998739,"numValue":0.0572794328268617,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20740,"numValue":4.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15966 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,966 | train | mutant | 4,873,910 | 336 | 4,880,484 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T68E | T68E | 1 | 1 | 0 | 0 | 68 | T | E | 4 | CONSERVATION | 1MJC | 50 | null | 68 | A | E | false | false | 46.382902 | 27.085715 | 5,003,029 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.007698 | 0.043243 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998740,"numValue":-0.00769844279304415,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998741,"numValue":0.0432427294812427,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20740,"numValue":4.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15967 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,967 | train | mutant | 4,873,911 | 336 | 4,880,485 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T68F | T68F | 1 | 1 | 0 | 0 | 68 | T | F | 4 | CONSERVATION | 1MJC | 50 | null | 68 | A | E | false | false | 46.382902 | 27.085715 | 5,003,030 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.141041 | 0.046399 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998742,"numValue":-0.141040778818893,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998743,"numValue":0.0463988874567354,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20740,"numValue":4.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15968 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,968 | train | mutant | 4,873,912 | 336 | 4,880,486 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T68G | T68G | 1 | 1 | 0 | 0 | 68 | T | G | 4 | CONSERVATION | 1MJC | 50 | null | 68 | A | E | false | false | 46.382902 | 27.085715 | 5,003,031 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.289646 | 0.033086 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998744,"numValue":-0.289645925244046,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998745,"numValue":0.0330855232536433,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20740,"numValue":4.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15969 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,969 | train | mutant | 4,873,913 | 336 | 4,880,487 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T68H | T68H | 1 | 1 | 0 | 0 | 68 | T | H | 4 | CONSERVATION | 1MJC | 50 | null | 68 | A | E | false | false | 46.382902 | 27.085715 | 5,003,032 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.00743 | 0.062487 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998746,"numValue":-0.00742959045514544,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998747,"numValue":0.0624866954726503,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20740,"numValue":4.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15970 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,970 | train | mutant | 4,873,914 | 336 | 4,880,488 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T68I | T68I | 1 | 1 | 0 | 0 | 68 | T | I | 4 | CONSERVATION | 1MJC | 50 | null | 68 | A | E | false | false | 46.382902 | 27.085715 | 5,003,033 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.073463 | 0.043985 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998748,"numValue":-0.0734626728932658,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998749,"numValue":0.0439850778177912,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20740,"numValue":4.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15971 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,971 | train | mutant | 4,873,915 | 336 | 4,880,489 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T68K | T68K | 1 | 1 | 0 | 0 | 68 | T | K | 4 | CONSERVATION | 1MJC | 50 | null | 68 | A | E | false | false | 46.382902 | 27.085715 | 5,003,034 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.022426 | 0.036806 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998750,"numValue":0.0224263563738646,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998751,"numValue":0.0368058148619098,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20740,"numValue":4.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15972 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,972 | train | mutant | 4,873,916 | 336 | 4,880,490 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T68L | T68L | 1 | 1 | 0 | 0 | 68 | T | L | 4 | CONSERVATION | 1MJC | 50 | null | 68 | A | E | false | false | 46.382902 | 27.085715 | 5,003,035 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.084677 | 0.027352 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998752,"numValue":-0.0846772550088556,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998753,"numValue":0.027351871597036,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20740,"numValue":4.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15973 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,973 | train | mutant | 4,873,917 | 336 | 4,880,491 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T68M | T68M | 1 | 1 | 0 | 0 | 68 | T | M | 4 | CONSERVATION | 1MJC | 50 | null | 68 | A | E | false | false | 46.382902 | 27.085715 | 5,003,036 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.013579 | 0.037296 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998754,"numValue":0.0135787979747101,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998755,"numValue":0.0372955613347694,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20740,"numValue":4.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15974 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,974 | train | mutant | 4,873,918 | 336 | 4,880,492 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T68N | T68N | 1 | 1 | 0 | 0 | 68 | T | N | 4 | CONSERVATION | 1MJC | 50 | null | 68 | A | E | false | false | 46.382902 | 27.085715 | 5,003,037 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.118221 | 0.055173 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998756,"numValue":-0.118221322420947,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998757,"numValue":0.0551733573299839,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20740,"numValue":4.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15976 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,976 | train | mutant | 4,873,920 | 336 | 4,880,494 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T68Q | T68Q | 1 | 1 | 0 | 0 | 68 | T | Q | 4 | CONSERVATION | 1MJC | 50 | null | 68 | A | E | false | false | 46.382902 | 27.085715 | 5,003,039 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.003223 | 0.036264 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998760,"numValue":0.00322271823314168,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998761,"numValue":0.0362635544376189,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20740,"numValue":4.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15977 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,977 | train | mutant | 4,873,921 | 336 | 4,880,495 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T68R | T68R | 1 | 1 | 0 | 0 | 68 | T | R | 4 | CONSERVATION | 1MJC | 50 | null | 68 | A | E | false | false | 46.382902 | 27.085715 | 5,003,040 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.017196 | 0.024361 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998762,"numValue":-0.017196020160591,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998763,"numValue":0.0243605137869962,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20740,"numValue":4.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15978 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,978 | train | mutant | 4,873,922 | 336 | 4,880,496 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T68S | T68S | 1 | 1 | 0 | 0 | 68 | T | S | 4 | CONSERVATION | 1MJC | 50 | null | 68 | A | E | false | false | 46.382902 | 27.085715 | 5,003,041 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.044599 | 0.029796 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998764,"numValue":-0.0445993036250623,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998765,"numValue":0.0297964834307243,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20740,"numValue":4.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15979 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,979 | train | mutant | 4,873,962 | 336 | 4,880,536 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T68V | T68V | 1 | 1 | 0 | 0 | 68 | T | V | 4 | CONSERVATION | 1MJC | 50 | null | 68 | A | E | false | false | 46.382902 | 27.085715 | 5,003,081 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.01083 | 0.032909 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998844,"numValue":0.0108299056634527,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998845,"numValue":0.0329090494214037,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20740,"numValue":4.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15980 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,980 | train | mutant | 4,873,963 | 336 | 4,880,537 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T68Y | T68Y | 1 | 1 | 0 | 0 | 68 | T | Y | 4 | CONSERVATION | 1MJC | 50 | null | 68 | A | E | false | false | 46.382902 | 27.085715 | 5,003,083 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.118614 | 0.051806 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998848,"numValue":-0.118614422445029,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998849,"numValue":0.0518060274254831,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20740,"numValue":4.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15981 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,981 | train | mutant | 4,873,923 | 336 | 4,880,497 | 70 | 69 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delS69 | delS69 | 1 | 0 | 1 | 0 | 69 | S | - | 3 | CONSERVATION | 1MJC | 50 | null | 69 | A | E | false | false | 58.757789 | 34.306667 | 5,003,042 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.147366 | 0.121587 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998766,"numValue":-1.14736647947472,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998767,"numValue":0.121586539412818,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20741,"numValue":3.0,"position":69,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15982 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,982 | train | mutant | 4,873,924 | 336 | 4,880,498 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S69A | S69A | 1 | 1 | 0 | 0 | 69 | S | A | 3 | CONSERVATION | 1MJC | 50 | null | 69 | A | E | false | false | 58.757789 | 34.306667 | 5,003,043 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.026421 | 0.033827 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998768,"numValue":0.0264205334042669,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998769,"numValue":0.0338265448776105,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20741,"numValue":3.0,"position":69,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15983 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,983 | train | mutant | 4,873,925 | 336 | 4,880,499 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S69C | S69C | 1 | 1 | 0 | 0 | 69 | S | C | 3 | CONSERVATION | 1MJC | 50 | null | 69 | A | E | false | false | 58.757789 | 34.306667 | 5,003,044 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.044375 | 0.046399 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998770,"numValue":-0.0443753770042015,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998771,"numValue":0.0463988242799458,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20741,"numValue":3.0,"position":69,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15984 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,984 | train | mutant | 4,873,926 | 336 | 4,880,500 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S69D | S69D | 1 | 1 | 0 | 0 | 69 | S | D | 3 | CONSERVATION | 1MJC | 50 | null | 69 | A | E | false | false | 58.757789 | 34.306667 | 5,003,045 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.050058 | 0.042513 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998772,"numValue":-0.0500584802094978,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998773,"numValue":0.0425128410115288,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20741,"numValue":3.0,"position":69,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15986 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,986 | train | mutant | 4,873,928 | 336 | 4,880,502 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S69F | S69F | 1 | 1 | 0 | 0 | 69 | S | F | 3 | CONSERVATION | 1MJC | 50 | null | 69 | A | E | false | false | 58.757789 | 34.306667 | 5,003,047 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.010119 | 0.04607 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998776,"numValue":0.0101188157984617,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998777,"numValue":0.0460699329330118,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20741,"numValue":3.0,"position":69,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15987 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,987 | train | mutant | 4,873,929 | 336 | 4,880,503 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S69G | S69G | 1 | 1 | 0 | 0 | 69 | S | G | 3 | CONSERVATION | 1MJC | 50 | null | 69 | A | E | false | false | 58.757789 | 34.306667 | 5,003,048 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.027943 | 0.038628 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998778,"numValue":-0.027943094033255,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998779,"numValue":0.0386277211592362,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20741,"numValue":3.0,"position":69,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15988 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,988 | train | mutant | 4,873,930 | 336 | 4,880,504 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S69H | S69H | 1 | 1 | 0 | 0 | 69 | S | H | 3 | CONSERVATION | 1MJC | 50 | null | 69 | A | E | false | false | 58.757789 | 34.306667 | 5,003,049 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.005465 | 0.066146 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998780,"numValue":-0.00546479229906534,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998781,"numValue":0.0661461688914768,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20741,"numValue":3.0,"position":69,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15989 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,989 | train | mutant | 4,873,931 | 336 | 4,880,505 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S69I | S69I | 1 | 1 | 0 | 0 | 69 | S | I | 3 | CONSERVATION | 1MJC | 50 | null | 69 | A | E | false | false | 58.757789 | 34.306667 | 5,003,050 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.024746 | 0.044018 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998782,"numValue":-0.0247463484802758,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998783,"numValue":0.0440183439073291,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20741,"numValue":3.0,"position":69,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15990 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,990 | train | mutant | 4,873,932 | 336 | 4,880,506 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S69K | S69K | 1 | 1 | 0 | 0 | 69 | S | K | 3 | CONSERVATION | 1MJC | 50 | null | 69 | A | E | false | false | 58.757789 | 34.306667 | 5,003,051 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.014581 | 0.053556 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998784,"numValue":0.0145805010717898,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998785,"numValue":0.0535562631648474,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20741,"numValue":3.0,"position":69,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15991 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,991 | train | mutant | 4,873,933 | 336 | 4,880,507 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S69L | S69L | 1 | 1 | 0 | 0 | 69 | S | L | 3 | CONSERVATION | 1MJC | 50 | null | 69 | A | E | false | false | 58.757789 | 34.306667 | 5,003,052 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.056922 | 0.026894 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998786,"numValue":0.0569215854513681,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998787,"numValue":0.0268944576011571,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20741,"numValue":3.0,"position":69,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15992 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,992 | train | mutant | 4,873,934 | 336 | 4,880,508 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S69M | S69M | 1 | 1 | 0 | 0 | 69 | S | M | 3 | CONSERVATION | 1MJC | 50 | null | 69 | A | E | false | false | 58.757789 | 34.306667 | 5,003,053 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.000473 | 0.043712 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998788,"numValue":-0.000473123957555518,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998789,"numValue":0.0437121049492829,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20741,"numValue":3.0,"position":69,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15993 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,993 | train | mutant | 4,873,935 | 336 | 4,880,509 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S69N | S69N | 1 | 1 | 0 | 0 | 69 | S | N | 3 | CONSERVATION | 1MJC | 50 | null | 69 | A | E | false | false | 58.757789 | 34.306667 | 5,003,054 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.199622 | 0.054952 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998790,"numValue":-0.199621807943349,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998791,"numValue":0.0549516910342615,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20741,"numValue":3.0,"position":69,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15994 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,994 | train | mutant | 4,873,936 | 336 | 4,880,510 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S69P | S69P | 1 | 1 | 0 | 0 | 69 | S | P | 3 | CONSERVATION | 1MJC | 50 | null | 69 | A | E | false | false | 58.757789 | 34.306667 | 5,003,055 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.049314 | 0.038595 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998792,"numValue":0.0493136960567286,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998793,"numValue":0.0385952342501031,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20741,"numValue":3.0,"position":69,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15995 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,995 | train | mutant | 4,873,937 | 336 | 4,880,511 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S69Q | S69Q | 1 | 1 | 0 | 0 | 69 | S | Q | 3 | CONSERVATION | 1MJC | 50 | null | 69 | A | E | false | false | 58.757789 | 34.306667 | 5,003,056 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.000835 | 0.058179 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998794,"numValue":-0.000834635586845066,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998795,"numValue":0.0581794493712834,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20741,"numValue":3.0,"position":69,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15996 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,996 | train | mutant | 4,873,938 | 336 | 4,880,512 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S69R | S69R | 1 | 1 | 0 | 0 | 69 | S | R | 3 | CONSERVATION | 1MJC | 50 | null | 69 | A | E | false | false | 58.757789 | 34.306667 | 5,003,057 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.029155 | 0.033862 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998796,"numValue":-0.02915538642895,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998797,"numValue":0.0338624784315976,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20741,"numValue":3.0,"position":69,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15997 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,997 | train | mutant | 4,873,958 | 336 | 4,880,532 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S69T | S69T | 1 | 1 | 0 | 0 | 69 | S | T | 3 | CONSERVATION | 1MJC | 50 | null | 69 | A | E | false | false | 58.757789 | 34.306667 | 5,003,077 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.048 | 0.040035 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998836,"numValue":0.0479996188333696,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998837,"numValue":0.0400353912865431,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20741,"numValue":3.0,"position":69,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15998 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,998 | train | mutant | 4,873,959 | 336 | 4,880,533 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S69V | S69V | 1 | 1 | 0 | 0 | 69 | S | V | 3 | CONSERVATION | 1MJC | 50 | null | 69 | A | E | false | false | 58.757789 | 34.306667 | 5,003,078 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.052119 | 0.031519 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998838,"numValue":0.0521194474786122,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998839,"numValue":0.0315186125183668,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20741,"numValue":3.0,"position":69,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:15999 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 15,999 | train | mutant | 4,873,960 | 336 | 4,880,534 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S69W | S69W | 1 | 1 | 0 | 0 | 69 | S | W | 3 | CONSERVATION | 1MJC | 50 | null | 69 | A | E | false | false | 58.757789 | 34.306667 | 5,003,079 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.126031 | 0.046723 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998840,"numValue":-0.126031377542257,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998841,"numValue":0.0467232932516089,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20741,"numValue":3.0,"position":69,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16000 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,000 | train | mutant | 4,873,961 | 336 | 4,880,535 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S69Y | S69Y | 1 | 1 | 0 | 0 | 69 | S | Y | 3 | CONSERVATION | 1MJC | 50 | null | 69 | A | E | false | false | 58.757789 | 34.306667 | 5,003,080 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.129333 | 0.055837 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998842,"numValue":-0.129332715780215,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998843,"numValue":0.0558370646027862,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20741,"numValue":3.0,"position":69,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16001 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,001 | train | mutant | 4,873,939 | 336 | 4,880,513 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L70A | L70A | 1 | 1 | 0 | 0 | 70 | L | A | 6 | CONSERVATION | 1MJC | 50 | null | 70 | A | L | false | false | 120.534717 | 40.563333 | 5,003,058 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.078254 | 0.057872 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998798,"numValue":-0.0782535794367623,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998799,"numValue":0.0578718064845797,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20742,"numValue":6.0,"position":70,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16002 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,002 | train | mutant | 4,873,940 | 336 | 4,880,514 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L70C | L70C | 1 | 1 | 0 | 0 | 70 | L | C | 6 | CONSERVATION | 1MJC | 50 | null | 70 | A | L | false | false | 120.534717 | 40.563333 | 5,003,059 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.074801 | 0.062828 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998800,"numValue":-0.0748013188681299,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998801,"numValue":0.062828313432864,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20742,"numValue":6.0,"position":70,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16003 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,003 | train | mutant | 4,873,941 | 336 | 4,880,515 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L70D | L70D | 1 | 1 | 0 | 0 | 70 | L | D | 6 | CONSERVATION | 1MJC | 50 | null | 70 | A | L | false | false | 120.534717 | 40.563333 | 5,003,060 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.287444 | 0.114611 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998802,"numValue":-0.287443863144859,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998803,"numValue":0.114611470860517,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20742,"numValue":6.0,"position":70,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16004 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,004 | train | mutant | 4,873,942 | 336 | 4,880,516 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L70E | L70E | 1 | 1 | 0 | 0 | 70 | L | E | 6 | CONSERVATION | 1MJC | 50 | null | 70 | A | L | false | false | 120.534717 | 40.563333 | 5,003,061 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.059889 | 0.070572 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998804,"numValue":-0.0598887886688567,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998805,"numValue":0.070571632805443,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20742,"numValue":6.0,"position":70,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16005 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,005 | train | mutant | 4,873,943 | 336 | 4,880,517 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L70F | L70F | 1 | 1 | 0 | 0 | 70 | L | F | 6 | CONSERVATION | 1MJC | 50 | null | 70 | A | L | false | false | 120.534717 | 40.563333 | 5,003,062 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.032479 | 0.066838 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998806,"numValue":-0.0324791875254269,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998807,"numValue":0.0668383337981653,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20742,"numValue":6.0,"position":70,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16006 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,006 | train | mutant | 4,873,944 | 336 | 4,880,518 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L70G | L70G | 1 | 1 | 0 | 0 | 70 | L | G | 6 | CONSERVATION | 1MJC | 50 | null | 70 | A | L | false | false | 120.534717 | 40.563333 | 5,003,063 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.170401 | 0.04771 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998808,"numValue":-0.170401138831829,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998809,"numValue":0.0477104305888678,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20742,"numValue":6.0,"position":70,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16007 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,007 | train | mutant | 4,873,945 | 336 | 4,880,519 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L70H | L70H | 1 | 1 | 0 | 0 | 70 | L | H | 6 | CONSERVATION | 1MJC | 50 | null | 70 | A | L | false | false | 120.534717 | 40.563333 | 5,003,064 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.079271 | 0.102983 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998810,"numValue":-0.0792714277134025,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998811,"numValue":0.10298287018385,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20742,"numValue":6.0,"position":70,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16008 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,008 | train | mutant | 4,873,946 | 336 | 4,880,520 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L70I | L70I | 1 | 1 | 0 | 0 | 70 | L | I | 6 | CONSERVATION | 1MJC | 50 | null | 70 | A | L | false | false | 120.534717 | 40.563333 | 5,003,065 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.022076 | 0.098237 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998812,"numValue":0.0220760761738347,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998813,"numValue":0.0982368893573916,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20742,"numValue":6.0,"position":70,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16009 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,009 | train | mutant | 4,873,947 | 336 | 4,880,521 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L70K | L70K | 1 | 1 | 0 | 0 | 70 | L | K | 6 | CONSERVATION | 1MJC | 50 | null | 70 | A | L | false | false | 120.534717 | 40.563333 | 5,003,066 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.292782 | 0.140237 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998814,"numValue":-0.292781599900426,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998815,"numValue":0.140237099858945,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20742,"numValue":6.0,"position":70,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16010 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,010 | train | mutant | 4,873,948 | 336 | 4,880,522 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L70M | L70M | 1 | 1 | 0 | 0 | 70 | L | M | 6 | CONSERVATION | 1MJC | 50 | null | 70 | A | L | false | false | 120.534717 | 40.563333 | 5,003,067 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.03094 | 0.041678 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998816,"numValue":-0.0309404817168785,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998817,"numValue":0.0416775876960745,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20742,"numValue":6.0,"position":70,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16011 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,011 | train | mutant | 4,873,949 | 336 | 4,880,523 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L70N | L70N | 1 | 1 | 0 | 0 | 70 | L | N | 6 | CONSERVATION | 1MJC | 50 | null | 70 | A | L | false | false | 120.534717 | 40.563333 | 5,003,068 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.189839 | 0.133202 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998818,"numValue":-0.189838531094015,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998819,"numValue":0.133202013356539,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20742,"numValue":6.0,"position":70,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16012 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,012 | train | mutant | 4,873,950 | 336 | 4,880,524 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L70P | L70P | 1 | 1 | 0 | 0 | 70 | L | P | 6 | CONSERVATION | 1MJC | 50 | null | 70 | A | L | false | false | 120.534717 | 40.563333 | 5,003,069 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.237164 | 0.05888 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998820,"numValue":-0.237163562207487,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998821,"numValue":0.0588804941267303,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20742,"numValue":6.0,"position":70,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16013 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,013 | train | mutant | 4,873,951 | 336 | 4,880,525 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L70Q | L70Q | 1 | 1 | 0 | 0 | 70 | L | Q | 6 | CONSERVATION | 1MJC | 50 | null | 70 | A | L | false | false | 120.534717 | 40.563333 | 5,003,070 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.103584 | 0.071103 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998822,"numValue":-0.103583962238531,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998823,"numValue":0.0711029496058492,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20742,"numValue":6.0,"position":70,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16014 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,014 | train | mutant | 4,873,952 | 336 | 4,880,526 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L70R | L70R | 1 | 1 | 0 | 0 | 70 | L | R | 6 | CONSERVATION | 1MJC | 50 | null | 70 | A | L | false | false | 120.534717 | 40.563333 | 5,003,071 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.17125 | 0.040576 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998824,"numValue":-0.171249813705248,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998825,"numValue":0.0405759669964451,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20742,"numValue":6.0,"position":70,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16015 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,015 | train | mutant | 4,873,953 | 336 | 4,880,527 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L70S | L70S | 1 | 1 | 0 | 0 | 70 | L | S | 6 | CONSERVATION | 1MJC | 50 | null | 70 | A | L | false | false | 120.534717 | 40.563333 | 5,003,072 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.006547 | 0.044223 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998826,"numValue":-0.00654651932961884,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998827,"numValue":0.044222959489507,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20742,"numValue":6.0,"position":70,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16016 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,016 | train | mutant | 4,873,954 | 336 | 4,880,528 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L70T | L70T | 1 | 1 | 0 | 0 | 70 | L | T | 6 | CONSERVATION | 1MJC | 50 | null | 70 | A | L | false | false | 120.534717 | 40.563333 | 5,003,073 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.095685 | 0.054936 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998828,"numValue":-0.0956847576474736,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998829,"numValue":0.0549363601333223,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20742,"numValue":6.0,"position":70,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16017 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,017 | train | mutant | 4,873,955 | 336 | 4,880,529 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L70V | L70V | 1 | 1 | 0 | 0 | 70 | L | V | 6 | CONSERVATION | 1MJC | 50 | null | 70 | A | L | false | false | 120.534717 | 40.563333 | 5,003,074 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.016267 | 0.041596 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998830,"numValue":-0.0162666193893691,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998831,"numValue":0.0415964125411017,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20742,"numValue":6.0,"position":70,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16018 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,018 | train | mutant | 4,873,956 | 336 | 4,880,530 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L70W | L70W | 1 | 1 | 0 | 0 | 70 | L | W | 6 | CONSERVATION | 1MJC | 50 | null | 70 | A | L | false | false | 120.534717 | 40.563333 | 5,003,075 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.083113 | 0.0371 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998832,"numValue":-0.0831125765201443,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998833,"numValue":0.0370995167370452,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20742,"numValue":6.0,"position":70,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16019 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,019 | train | mutant | 4,873,957 | 336 | 4,880,531 | 70 | 70 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | 34 | Cold shock protein CspA | Escherichia coli (strain K12) | 1 | P0A9X9 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L70Y | L70Y | 1 | 1 | 0 | 0 | 70 | L | Y | 6 | CONSERVATION | 1MJC | 50 | null | 70 | A | L | false | false | 120.534717 | 40.563333 | 5,003,076 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.124913 | 0.061969 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":11998834,"numValue":-0.12491314836661,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":11998835,"numValue":0.0619687019552032,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20742,"numValue":6.0,"position":70,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16020 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,020 | train | sequence | 341 | 341 | -1 | 66 | -1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 19,723 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | null | 76.9 | null | null | null | null | null | 58.56 | null | null | null | null | null | null | null | null | null | yes | TM|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":"BUFFER_CONC"}] | [{"datasets":[],"id":72534,"numValue":76.9,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":72535,"numValue":58.56,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":72536,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | ||||||||||||||||||||||||||
fireprotdb:16021 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,021 | train | sequence | 341 | 341 | -1 | 66 | -1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 20,131 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | 70 | NaCl | 2 M | null | null | 2.2 | null | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","typ... | [{"datasets":[],"id":73792,"numValue":2.2,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":73793,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | ||||||||||||||||||||||||
fireprotdb:16022 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,022 | train | sequence | 341 | 341 | -1 | 66 | -1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 22,337 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | null | 76.9 | null | null | null | null | null | 58.56 | null | null | null | null | null | null | null | null | null | yes | TM|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","type":"BUFFER_CONC"}] | [{"datasets":[],"id":80654,"numValue":76.9,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":80655,"numValue":58.56,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":80656,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | ||||||||||||||||||||||||||
fireprotdb:16023 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,023 | train | sequence | 341 | 341 | -1 | 66 | -1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 22,482 | ProTherm | 7 | CD | Thermal | sodium cacodylate | 100 mM | null | 76.9 | null | null | null | null | null | 58.56 | null | null | null | null | null | null | null | null | null | yes | TM|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC | 1610 | ARTICLE | The effects of ionic strength on protein stability: the cold shock protein family. | 2,002 | 10.1016/S0022-2836(02)00259-0 | 12051927 | J Mol Biol;319;541-54 | 4 | Schmid Franz X|Brooks Charles L|Dominy Brian N|Perl Dieter | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","type":"BUFFER_CONC"}] | [{"datasets":[],"id":81074,"numValue":76.9,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":81075,"numValue":58.56,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":81076,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | ||||||||||||||||||||||||||
fireprotdb:16024 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,024 | train | sequence | 341 | 341 | -1 | 66 | -1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 22,484 | ProTherm | 7 | CD | Thermal | sodium cacodylate | 100 mM | null | NaCl | 2 M | 84.4 | null | null | null | null | null | 61.42 | null | null | null | null | null | null | null | null | null | yes | TM|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC | 1610 | ARTICLE | The effects of ionic strength on protein stability: the cold shock protein family. | 2,002 | 10.1016/S0022-2836(02)00259-0 | 12051927 | J Mol Biol;319;541-54 | 4 | Schmid Franz X|Brooks Charles L|Dominy Brian N|Perl Dieter | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"I... | [{"datasets":[],"id":81080,"numValue":84.4,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":81081,"numValue":61.42,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":81082,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | ||||||||||||||||||||||||
fireprotdb:16025 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,025 | train | sequence | 341 | 341 | -1 | 66 | -1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 23,378 | ProTherm | 7 | CD | Thermal | Na cacodylate/HCl | 0.1 M | null | 76.9 | null | null | null | null | 0.96 | 58.56 | null | null | null | null | null | null | null | null | null | Yes | TM|DCP|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC | 223 | ARTICLE | The correlation between protein stability and dipole moment: a critical test. | 2,006 | 10.1093/protein/gzl019 | 16720692 | Protein Eng Des Sel;19;355-8 | 2 | Wunderlich Michael|Schmid Franz X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Na cacodylate/HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":"BUFFER_CONC"}] | [{"datasets":[],"id":83724,"numValue":76.9,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":83725,"numValue":0.96,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":83726,"numValue":58.56,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":83727,"numValue":null,"references"... | ||||||||||||||||||||||||||
fireprotdb:16026 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,026 | train | sequence | 341 | 341 | -1 | 66 | -1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 23,379 | ProTherm | 7 | DSC | Thermal | Na cacodylate/HCl | 0.1 M | null | 76.9 | null | null | null | 61.42 | 0.96 | null | null | null | null | null | null | null | null | null | null | Yes | TM|DH|DCP|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC | 223 | ARTICLE | The correlation between protein stability and dipole moment: a critical test. | 2,006 | 10.1093/protein/gzl019 | 16720692 | Protein Eng Des Sel;19;355-8 | 2 | Wunderlich Michael|Schmid Franz X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Na cacodylate/HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":"BUFFER_CONC"}] | [{"datasets":[],"id":83728,"numValue":76.9,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":83729,"numValue":61.42,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":83730,"numValue":0.96,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":83731,"numValue":null,"references":[... | ||||||||||||||||||||||||||
fireprotdb:16027 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,027 | train | sequence | 341 | 341 | -1 | 66 | -1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 25,258 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | null | null | 1.08 | null | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":89024,"numValue":1.08,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":89025,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | ||||||||||||||||||||||||||
fireprotdb:16028 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,028 | train | sequence | 341 | 341 | -1 | 66 | -1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 25,259 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | NaCl | 2 M | null | null | 2.2 | null | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":89026,"numValue":2.2,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":89027,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | ||||||||||||||||||||||||
fireprotdb:16029 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,029 | train | sequence | 341 | 341 | -1 | 66 | -1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 25,267 | ProTherm | 7 | CD | Thermal | sodium cacodylate | 100 mM | 60 | null | null | 2.44 | null | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC | 1610 | ARTICLE | The effects of ionic strength on protein stability: the cold shock protein family. | 2,002 | 10.1016/S0022-2836(02)00259-0 | 12051927 | J Mol Biol;319;541-54 | 4 | Schmid Franz X|Brooks Charles L|Dominy Brian N|Perl Dieter | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":60.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","type":... | [{"datasets":[],"id":89048,"numValue":2.44,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":89049,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | ||||||||||||||||||||||||||
fireprotdb:16030 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,030 | train | sequence | 341 | 341 | -1 | 66 | -1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 25,269 | ProTherm | 7 | CD | Thermal | sodium cacodylate | 100 mM | 60 | NaCl | 2 M | null | null | 3.37 | null | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC | 1610 | ARTICLE | The effects of ionic strength on protein stability: the cold shock protein family. | 2,002 | 10.1016/S0022-2836(02)00259-0 | 12051927 | J Mol Biol;319;541-54 | 4 | Schmid Franz X|Brooks Charles L|Dominy Brian N|Perl Dieter | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":60.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","type":... | [{"datasets":[],"id":89052,"numValue":3.37,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":89053,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | ||||||||||||||||||||||||
fireprotdb:16031 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,031 | train | sequence | 341 | 341 | -1 | 66 | -1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 25,677 | ProTherm | 7 | CD | GdnHCl | sodium cacodylate-HCl | 100 mM | 25 | null | null | 1.2 | null | null | null | null | 2.68 | 1.77 | null | null | null | null | null | null | null | yes | DG|M|CM|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","typ... | [{"datasets":[],"id":90119,"numValue":1.2,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":90120,"numValue":1.77,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":90121,"numValue":2.68,"references":[],"strValue":null,"type":"CM"},{"datasets":[],"id":90122,"numValue":null,"references":[],"s... | ||||||||||||||||||||||||||
fireprotdb:16032 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,032 | train | sequence | 341 | 341 | -1 | 66 | -1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 25,964 | ProTherm | 7 | Fluorescence | GdnHCl | sodium cacodylate | 100 mM | 25 | null | null | 3.63 | null | null | null | null | 2.36 | 1.53 | null | null | null | null | null | null | null | yes | DG|M|CM|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC | 623 | ARTICLE | Rapid collapse precedes the fast two-state folding of the cold shock protein. | 2,004 | 10.1016/j.jmb.2003.11.050 | 14729346 | J Mol Biol;335;1309-23 | 2 | Schmid Franz X|Magg Christine | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"100 mM... | [{"datasets":[],"id":91260,"numValue":3.63,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":91261,"numValue":1.53,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":91262,"numValue":2.36,"references":[],"strValue":null,"type":"CM"},{"datasets":[],"id":91263,"numValue":null,"references":[],"... | ||||||||||||||||||||||||||
fireprotdb:16033 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,033 | train | mutant | 4,901,204 | 341 | 4,907,790 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delM1 | delM1 | 1 | 0 | 1 | 0 | 1 | M | - | 9 | CONSERVATION | 1C9O | 231 | null | 1 | A|B | L | true | true | 158.186514 | 33.460625 | 5,083,019 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.011855 | 0.240822 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158720,"numValue":-1.01185475204187,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158721,"numValue":0.240821941361941,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20743,"numValue":9.0,"position":1,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16034 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,034 | train | mutant | 4,901,205 | 341 | 4,907,791 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | M1A | M1A | 1 | 1 | 0 | 0 | 1 | M | A | 9 | CONSERVATION | 1C9O | 231 | null | 1 | A|B | L | true | true | 158.186514 | 33.460625 | 5,083,020 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.046046 | 0.04732 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158722,"numValue":-0.0460464643116717,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158723,"numValue":0.0473195411655369,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20743,"numValue":9.0,"position":1,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16035 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,035 | train | mutant | 4,901,206 | 341 | 4,907,792 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | M1C | M1C | 1 | 1 | 0 | 0 | 1 | M | C | 9 | CONSERVATION | 1C9O | 231 | null | 1 | A|B | L | true | true | 158.186514 | 33.460625 | 5,083,021 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.101835 | 0.101656 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158724,"numValue":-0.101835122765495,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158725,"numValue":0.101656046595714,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20743,"numValue":9.0,"position":1,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16036 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,036 | train | mutant | 4,901,207 | 341 | 4,907,793 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | M1D | M1D | 1 | 1 | 0 | 0 | 1 | M | D | 9 | CONSERVATION | 1C9O | 231 | null | 1 | A|B | L | true | true | 158.186514 | 33.460625 | 5,083,022 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.086176 | 0.08486 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158726,"numValue":-0.0861764795979213,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158727,"numValue":0.0848602904970247,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20743,"numValue":9.0,"position":1,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16037 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,037 | train | mutant | 4,901,208 | 341 | 4,907,794 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | M1E | M1E | 1 | 1 | 0 | 0 | 1 | M | E | 9 | CONSERVATION | 1C9O | 231 | null | 1 | A|B | L | true | true | 158.186514 | 33.460625 | 5,083,023 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.007861 | 0.053365 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158728,"numValue":0.0078613312268459,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158729,"numValue":0.0533649831247755,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20743,"numValue":9.0,"position":1,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16038 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,038 | train | mutant | 4,901,209 | 341 | 4,907,795 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | M1F | M1F | 1 | 1 | 0 | 0 | 1 | M | F | 9 | CONSERVATION | 1C9O | 231 | null | 1 | A|B | L | true | true | 158.186514 | 33.460625 | 5,083,024 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.024912 | 0.065457 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158730,"numValue":-0.0249118010963223,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158731,"numValue":0.0654568154771212,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20743,"numValue":9.0,"position":1,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16039 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,039 | train | mutant | 4,901,210 | 341 | 4,907,796 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | M1G | M1G | 1 | 1 | 0 | 0 | 1 | M | G | 9 | CONSERVATION | 1C9O | 231 | null | 1 | A|B | L | true | true | 158.186514 | 33.460625 | 5,083,025 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.064312 | 0.050061 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158732,"numValue":-0.0643121150750581,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158733,"numValue":0.0500607995754241,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20743,"numValue":9.0,"position":1,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16040 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,040 | train | mutant | 4,901,211 | 341 | 4,907,797 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | M1H | M1H | 1 | 1 | 0 | 0 | 1 | M | H | 9 | CONSERVATION | 1C9O | 231 | null | 1 | A|B | L | true | true | 158.186514 | 33.460625 | 5,083,026 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.01579 | 0.177945 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158734,"numValue":0.0157902383668165,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158735,"numValue":0.177944747452682,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20743,"numValue":9.0,"position":1,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16041 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,041 | train | mutant | 4,901,212 | 341 | 4,907,798 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | M1I | M1I | 1 | 1 | 0 | 0 | 1 | M | I | 9 | CONSERVATION | 1C9O | 231 | null | 1 | A|B | L | true | true | 158.186514 | 33.460625 | 5,083,027 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.005991 | 0.074525 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158736,"numValue":-0.00599113819256008,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158737,"numValue":0.0745248509701781,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20743,"numValue":9.0,"position":1,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16042 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,042 | train | mutant | 4,901,213 | 341 | 4,907,799 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | M1K | M1K | 1 | 1 | 0 | 0 | 1 | M | K | 9 | CONSERVATION | 1C9O | 231 | null | 1 | A|B | L | true | true | 158.186514 | 33.460625 | 5,083,028 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.100351 | 0.068799 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158738,"numValue":-0.100350823761421,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158739,"numValue":0.068799274260775,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20743,"numValue":9.0,"position":1,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16043 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,043 | train | mutant | 4,901,214 | 341 | 4,907,800 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | M1L | M1L | 1 | 1 | 0 | 0 | 1 | M | L | 9 | CONSERVATION | 1C9O | 231 | null | 1 | A|B | L | true | true | 158.186514 | 33.460625 | 5,083,029 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.044017 | 0.044444 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158740,"numValue":-0.0440174086044259,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158741,"numValue":0.0444438956042066,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20743,"numValue":9.0,"position":1,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16046 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,046 | train | mutant | 4,902,485 | 341 | 4,909,071 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | M1Q | M1Q | 1 | 1 | 0 | 0 | 1 | M | Q | 9 | CONSERVATION | 1C9O | 231 | null | 1 | A|B | L | true | true | 158.186514 | 33.460625 | 5,084,331 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.020574 | 0.200223 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161344,"numValue":-0.0205744944618153,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161345,"numValue":0.200222806973525,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20743,"numValue":9.0,"position":1,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16047 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,047 | train | mutant | 4,902,486 | 341 | 4,909,072 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | M1R | M1R | 1 | 1 | 0 | 0 | 1 | M | R | 9 | CONSERVATION | 1C9O | 231 | null | 1 | A|B | L | true | true | 158.186514 | 33.460625 | 5,084,332 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.096487 | 0.046782 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161346,"numValue":-0.0964871412899555,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161347,"numValue":0.046782277089925,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20743,"numValue":9.0,"position":1,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16048 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,048 | train | mutant | 4,902,487 | 341 | 4,909,073 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | M1S | M1S | 1 | 1 | 0 | 0 | 1 | M | S | 9 | CONSERVATION | 1C9O | 231 | null | 1 | A|B | L | true | true | 158.186514 | 33.460625 | 5,084,333 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.048842 | 0.048957 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161348,"numValue":-0.0488419731388325,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161349,"numValue":0.0489569055405496,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20743,"numValue":9.0,"position":1,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16049 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,049 | train | mutant | 4,902,488 | 341 | 4,909,074 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | M1T | M1T | 1 | 1 | 0 | 0 | 1 | M | T | 9 | CONSERVATION | 1C9O | 231 | null | 1 | A|B | L | true | true | 158.186514 | 33.460625 | 5,084,334 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.029578 | 0.056659 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161350,"numValue":-0.0295780957289367,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161351,"numValue":0.0566593681667238,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20743,"numValue":9.0,"position":1,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16051 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,051 | train | mutant | 4,902,490 | 341 | 4,909,076 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | M1W | M1W | 1 | 1 | 0 | 0 | 1 | M | W | 9 | CONSERVATION | 1C9O | 231 | null | 1 | A|B | L | true | true | 158.186514 | 33.460625 | 5,084,336 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.085743 | 0.071637 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161354,"numValue":-0.0857431638742879,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161355,"numValue":0.0716371069493138,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20743,"numValue":9.0,"position":1,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16052 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,052 | train | mutant | 4,902,491 | 341 | 4,909,077 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | M1Y | M1Y | 1 | 1 | 0 | 0 | 1 | M | Y | 9 | CONSERVATION | 1C9O | 231 | null | 1 | A|B | L | true | true | 158.186514 | 33.460625 | 5,084,337 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.027241 | 0.15136 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161356,"numValue":0.0272413917856227,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161357,"numValue":0.151360264675172,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20743,"numValue":9.0,"position":1,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16053 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,053 | train | mutant | 307 | 341 | 342 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2L | Q2L | 1 | 1 | 0 | 0 | 2 | Q | L | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 552 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | null | 1C9O_A:Q2L | 80.9 | 4 | null | null | null | null | 57.84 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | AUTOMUTE_S1749.csv|M47andM8_S2760.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:Q2L"... | [{"datasets":[],"id":2192,"numValue":80.9,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","M47andM8_S2760.csv","Saraboji_S1791.csv"],"id":2193,"numValue":4.0,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":2194,"numValue":57.84,"references":[],"strValue":null,"type":"DHV... | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16054 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,054 | train | mutant | 307 | 341 | 342 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2L | Q2L | 1 | 1 | 0 | 0 | 2 | Q | L | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 4,174 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | null | 1C9O_A:Q2L | 80.9 | 4 | null | null | null | null | 57.84 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | AUTOMUTE_S1749.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:Q2L",... | [{"datasets":[],"id":15478,"numValue":80.9,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","Saraboji_S1791.csv"],"id":15479,"numValue":4.0,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":15480,"numValue":57.84,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[]... | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16055 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,055 | train | mutant | 307 | 341 | 342 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2L | Q2L | 1 | 1 | 0 | 0 | 2 | Q | L | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 6,610 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | 1C9O_A:Q2L | null | null | 1.63 | -0.55 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":23595,"numValue":1.63,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv"],"id":23596,"numValue":-0.55,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23597,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16056 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,056 | train | mutant | 307 | 341 | 342 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2L | Q2L | 1 | 1 | 0 | 0 | 2 | Q | L | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 6,622 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | NaCl | 2 M | 1C9O_A:Q2L | null | null | 2.49 | -0.29 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":23631,"numValue":2.49,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv"],"id":23632,"numValue":-0.29,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23633,"numValue":null,"references":[],"strValue":"yes","type":"REV... | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:16057 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,057 | train | mutant | 307 | 341 | 342 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2L | Q2L | 1 | 1 | 0 | 0 | 2 | Q | L | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 6,647 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | 70 | 1C9O_A:Q2L | null | null | 1.63 | -0.55 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","typ... | [{"datasets":[],"id":23702,"numValue":1.63,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv"],"id":23703,"numValue":-0.55,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23704,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16058 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,058 | train | mutant | 307 | 341 | 342 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2L | Q2L | 1 | 1 | 0 | 0 | 2 | Q | L | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 6,656 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | 70 | NaCl | 2 M | 1C9O_A:Q2L | null | null | 2.49 | -0.29 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","typ... | [{"datasets":[],"id":23729,"numValue":2.49,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv"],"id":23730,"numValue":-0.29,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23731,"numValue":null,"references":[],"strValue":"yes","type":"REV... | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:16059 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,059 | train | mutant | 307 | 341 | 342 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2L | Q2L | 1 | 1 | 0 | 0 | 2 | Q | L | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 8,797 | ProTherm | 7 | CD | GdnHCl | sodium cacodylate-HCl | 100 mM | 25 | 1C9O_A:Q2L | null | null | 1.6 | -0.41 | null | null | null | 2.95 | 1.7 | null | null | null | null | null | null | null | yes | DG|DDG|M|CM|REVERSIBILITY | potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","typ... | [{"datasets":[],"id":29739,"numValue":1.6,"references":[],"strValue":null,"type":"DG"},{"datasets":["potapov_with_uniprot_mapping.csv"],"id":29740,"numValue":-0.41,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":29741,"numValue":1.7,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":29742... | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16061 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,061 | train | mutant | 7,944 | 341 | 8,660 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | E50W|Q2C | E50W|Q2C | 2 | 2 | 0 | 0 | 50 | E | W | 3 | CONSERVATION | 1C9O | 231 | null | 2|50 | A|B | E | true | true | 59.384415 | 19.593056 | 16,940 | ProTherm | 7 | Fluorescence | GdnHCl | sodium cacodylate | 100 mM | 25 | 1C9O_A:Q2C 1C9O_A:E50W | null | null | 3.23 | 1.7 | null | null | null | 2.06 | 1.57 | null | null | null | null | null | null | null | yes | DG|DDG|M|CM|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 623 | ARTICLE | Rapid collapse precedes the fast two-state folding of the cold shock protein. | 2,004 | 10.1016/j.jmb.2003.11.050 | 14729346 | J Mol Biol;335;1309-23 | 2 | Schmid Franz X|Magg Christine | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"100 mM... | [{"datasets":[],"id":62260,"numValue":3.23,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":62261,"numValue":1.7,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":62262,"numValue":1.57,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":62263,"numValue":2.06,"references":[],"... | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20792,"numValue":5.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:16062 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,062 | train | mutant | 7,944 | 341 | 8,660 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | E50W|Q2C | E50W|Q2C | 2 | 2 | 0 | 0 | 50 | E | W | 3 | CONSERVATION | 1C9O | 231 | null | 2|50 | A|B | E | true | true | 59.384415 | 19.593056 | 16,941 | ProTherm | 7 | Fluorescence | GdnHCl | sodium cacodylate | 100 mM | 25 | 1C9O_A:Q2C 1C9O_A:E50W | null | null | 2.77 | 3.6 | null | null | null | 1.95 | 1.42 | null | null | null | null | null | null | null | yes | DG|DDG|M|CM|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 623 | ARTICLE | Rapid collapse precedes the fast two-state folding of the cold shock protein. | 2,004 | 10.1016/j.jmb.2003.11.050 | 14729346 | J Mol Biol;335;1309-23 | 2 | Schmid Franz X|Magg Christine | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"100 mM... | [{"datasets":[],"id":62265,"numValue":2.77,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":62266,"numValue":3.6,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":62267,"numValue":1.42,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":62268,"numValue":1.95,"references":[],"... | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20792,"numValue":5.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:16063 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,063 | train | mutant | 7,944 | 341 | 8,660 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | E50W|Q2C | E50W|Q2C | 2 | 2 | 0 | 0 | 50 | E | W | 3 | CONSERVATION | 1C9O | 231 | null | 2|50 | A|B | E | true | true | 59.384415 | 19.593056 | 16,942 | ProTherm | 7 | Fluorescence | GdnHCl | sodium cacodylate | 100 mM | 25 | 1C9O_A:Q2C 1C9O_A:E50W | null | null | 3.9 | -1.1 | null | null | null | 2.13 | 1.82 | null | null | null | null | null | null | null | yes | DG|DDG|M|CM|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 623 | ARTICLE | Rapid collapse precedes the fast two-state folding of the cold shock protein. | 2,004 | 10.1016/j.jmb.2003.11.050 | 14729346 | J Mol Biol;335;1309-23 | 2 | Schmid Franz X|Magg Christine | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"100 mM... | [{"datasets":[],"id":62270,"numValue":3.9,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":62271,"numValue":-1.1,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":62272,"numValue":1.82,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":62273,"numValue":2.13,"references":[],"... | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20792,"numValue":5.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:16064 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,064 | train | mutant | 7,944 | 341 | 8,660 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | E50W|Q2C | E50W|Q2C | 2 | 2 | 0 | 0 | 50 | E | W | 3 | CONSERVATION | 1C9O | 231 | null | 2|50 | A|B | E | true | true | 59.384415 | 19.593056 | 16,943 | ProTherm | 7 | Fluorescence | GdnHCl | sodium cacodylate | 100 mM | 25 | 1C9O_A:Q2C 1C9O_A:E50W | null | null | 2.92 | 0.3 | null | null | null | 2.02 | 1.44 | null | null | null | null | null | null | null | yes | DG|DDG|M|CM|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 623 | ARTICLE | Rapid collapse precedes the fast two-state folding of the cold shock protein. | 2,004 | 10.1016/j.jmb.2003.11.050 | 14729346 | J Mol Biol;335;1309-23 | 2 | Schmid Franz X|Magg Christine | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"100 mM... | [{"datasets":[],"id":62275,"numValue":2.92,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":62276,"numValue":0.3,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":62277,"numValue":1.44,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":62278,"numValue":2.02,"references":[],"... | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20792,"numValue":5.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:16065 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,065 | train | mutant | 4,901,215 | 341 | 4,907,801 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delQ2 | delQ2 | 1 | 0 | 1 | 0 | 2 | Q | - | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 5,083,030 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.166996 | 0.174053 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158742,"numValue":-1.16699600761061,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158743,"numValue":0.174052908350747,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16066 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,066 | train | mutant | 4,901,216 | 341 | 4,907,802 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2A | Q2A | 1 | 1 | 0 | 0 | 2 | Q | A | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 5,083,031 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.003058 | 0.046215 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158744,"numValue":-0.00305751368331112,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158745,"numValue":0.0462154930101587,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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