row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:16067 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,067 | train | mutant | 4,901,217 | 341 | 4,907,803 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2C | Q2C | 1 | 1 | 0 | 0 | 2 | Q | C | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 5,083,032 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.026777 | 0.060935 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158746,"numValue":0.0267766591900983,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158747,"numValue":0.0609353941179077,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16068 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,068 | train | mutant | 4,901,218 | 341 | 4,907,804 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2D | Q2D | 1 | 1 | 0 | 0 | 2 | Q | D | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 5,083,033 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.035603 | 0.073115 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158748,"numValue":-0.0356030218780591,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158749,"numValue":0.0731154782417096,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16069 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,069 | train | mutant | 4,901,219 | 341 | 4,907,805 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2E | Q2E | 1 | 1 | 0 | 0 | 2 | Q | E | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 5,083,034 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.010884 | 0.067192 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158750,"numValue":0.0108838714112589,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158751,"numValue":0.0671918566851576,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16070 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,070 | train | mutant | 4,901,220 | 341 | 4,907,806 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2F | Q2F | 1 | 1 | 0 | 0 | 2 | Q | F | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 5,083,035 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.047954 | 0.069145 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158752,"numValue":0.0479540019295263,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158753,"numValue":0.0691449784058132,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16071 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,071 | train | mutant | 4,901,221 | 341 | 4,907,807 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2G | Q2G | 1 | 1 | 0 | 0 | 2 | Q | G | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 5,083,036 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.043228 | 0.038676 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158754,"numValue":-0.0432278374089683,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158755,"numValue":0.0386762854912975,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16072 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,072 | train | mutant | 4,901,222 | 341 | 4,907,808 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2H | Q2H | 1 | 1 | 0 | 0 | 2 | Q | H | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 5,083,037 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.027261 | 0.083267 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158756,"numValue":0.0272609532341589,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158757,"numValue":0.0832667437667329,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16073 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,073 | train | mutant | 4,901,223 | 341 | 4,907,809 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2I | Q2I | 1 | 1 | 0 | 0 | 2 | Q | I | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 5,083,038 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.02821 | 0.078354 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158758,"numValue":0.0282099798737442,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158759,"numValue":0.0783542119910307,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16075 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,075 | train | mutant | 4,901,225 | 341 | 4,907,811 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2M | Q2M | 1 | 1 | 0 | 0 | 2 | Q | M | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 5,083,041 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.050578 | 0.065625 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158764,"numValue":0.0505781998892042,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158765,"numValue":0.0656248661031815,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16076 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,076 | train | mutant | 4,901,226 | 341 | 4,907,812 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2N | Q2N | 1 | 1 | 0 | 0 | 2 | Q | N | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 5,083,042 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.026274 | 0.115784 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158766,"numValue":-0.026273989239837,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158767,"numValue":0.115784213885246,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16077 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,077 | train | mutant | 4,901,227 | 341 | 4,907,813 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2P | Q2P | 1 | 1 | 0 | 0 | 2 | Q | P | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 5,083,043 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.206217 | 0.038219 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158768,"numValue":-0.206217383238858,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158769,"numValue":0.0382189803185049,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16078 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,078 | train | mutant | 4,902,477 | 341 | 4,909,063 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2R | Q2R | 1 | 1 | 0 | 0 | 2 | Q | R | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 5,084,323 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.006418 | 0.038127 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161328,"numValue":-0.00641793343334807,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161329,"numValue":0.0381273556791041,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16079 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,079 | train | mutant | 4,902,478 | 341 | 4,909,064 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2S | Q2S | 1 | 1 | 0 | 0 | 2 | Q | S | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 5,084,324 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.033508 | 0.035476 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161330,"numValue":-0.0335075758000241,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161331,"numValue":0.0354763288963735,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16080 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,080 | train | mutant | 4,902,479 | 341 | 4,909,065 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2T | Q2T | 1 | 1 | 0 | 0 | 2 | Q | T | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 5,084,325 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.029153 | 0.055869 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161332,"numValue":0.0291530788016519,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161333,"numValue":0.0558691804892518,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16081 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,081 | train | mutant | 4,902,480 | 341 | 4,909,066 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2V | Q2V | 1 | 1 | 0 | 0 | 2 | Q | V | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 5,084,326 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.018259 | 0.038873 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161334,"numValue":0.0182585375093731,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161335,"numValue":0.0388725046032497,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16082 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,082 | train | mutant | 4,902,481 | 341 | 4,909,067 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2W | Q2W | 1 | 1 | 0 | 0 | 2 | Q | W | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 5,084,327 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.001228 | 0.050893 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161336,"numValue":0.00122822185960066,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161337,"numValue":0.0508933288974093,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16083 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,083 | train | mutant | 4,902,482 | 341 | 4,909,068 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q2Y | Q2Y | 1 | 1 | 0 | 0 | 2 | Q | Y | 3 | CONSERVATION | 1C9O | 231 | null | 2 | A|B | E | true | false | 67.502991 | 19.218333 | 5,084,328 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.00297 | 0.050577 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161338,"numValue":0.00296978355048244,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161339,"numValue":0.0505774352143978,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20744,"numValue":3.0,"position":2,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16085 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,085 | train | mutant | 308 | 341 | 343 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3E | R3E | 1 | 1 | 0 | 0 | 3 | R | E | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 4,175 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | null | 1C9O_A:R3E | 59.1 | -17.8 | null | null | null | null | 45.65 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | AUTOMUTE_S1749.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:R3E",... | [{"datasets":[],"id":15482,"numValue":59.1,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","Saraboji_S1791.csv"],"id":15483,"numValue":-17.8,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":15484,"numValue":45.65,"references":[],"strValue":null,"type":"DHVH"},{"datasets":... | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16086 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,086 | train | mutant | 308 | 341 | 343 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3E | R3E | 1 | 1 | 0 | 0 | 3 | R | E | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 6,623 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | NaCl | 2 M | 1C9O_A:R3E | null | null | 1.2 | 1 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":23634,"numValue":1.2,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv"],"id":23635,"numValue":1.0,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23636,"numValue":null,"references":[],"strValue":"yes","type":"REVERS... | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:16087 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,087 | train | mutant | 308 | 341 | 343 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3E | R3E | 1 | 1 | 0 | 0 | 3 | R | E | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 6,657 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | 70 | NaCl | 2 M | 1C9O_A:R3E | null | null | 1.2 | 1 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","typ... | [{"datasets":[],"id":23732,"numValue":1.2,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv"],"id":23733,"numValue":1.0,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23734,"numValue":null,"references":[],"strValue":"yes","type":"REVERS... | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:16088 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,088 | train | mutant | 308 | 341 | 343 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3E | R3E | 1 | 1 | 0 | 0 | 3 | R | E | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 8,798 | ProTherm | 7 | CD | GdnHCl | sodium cacodylate-HCl | 100 mM | 25 | 1C9O_A:R3E | null | null | 0.36 | 0.84 | null | null | null | 2.23 | 1.6 | null | null | null | null | null | null | null | yes | DG|DDG|M|CM|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","typ... | [{"datasets":[],"id":29744,"numValue":0.36,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":29745,"numValue":0.84,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":29746,"numValue":1.6,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":29747,"numValue":2.23,"references":[],"... | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:16089 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,089 | train | mutant | 308 | 341 | 343 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3E | R3E | 1 | 1 | 0 | 0 | 3 | R | E | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 5,083,048 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.01889 | 0.040791 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158778,"numValue":-0.0188898388030387,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158779,"numValue":0.0407908662226278,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16090 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,090 | train | mutant | 309 | 341 | 344 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3L | R3L | 1 | 1 | 0 | 0 | 3 | R | L | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 554 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | null | 1C9O_A:R3L | 70.9 | -6 | null | null | null | null | 55.69 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | AUTOMUTE_S1749.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:R3L"... | [{"datasets":[],"id":2200,"numValue":70.9,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","Saraboji_S1791.csv"],"id":2201,"numValue":-6.0,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":2202,"numValue":55.69,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"... | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16091 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,091 | train | mutant | 309 | 341 | 344 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3L | R3L | 1 | 1 | 0 | 0 | 3 | R | L | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 6,611 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | 1C9O_A:R3L | null | null | 0.14 | 0.93 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":23598,"numValue":0.14,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv"],"id":23599,"numValue":0.93,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23600,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16092 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,092 | train | mutant | 309 | 341 | 344 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3L | R3L | 1 | 1 | 0 | 0 | 3 | R | L | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 6,624 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | NaCl | 2 M | 1C9O_A:R3L | null | null | 1.98 | 0.22 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":23637,"numValue":1.98,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv"],"id":23638,"numValue":0.22,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23639,"numValue":null,"references":[],"strValue":"yes","type":"REVE... | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:16095 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,095 | train | mutant | 310 | 341 | 345 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3K | R3K | 1 | 1 | 0 | 0 | 3 | R | K | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 555 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | null | 1C9O_A:R3K | 76.1 | -0.8 | null | null | null | null | 53.54 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | AUTOMUTE_S1749.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:R3K"... | [{"datasets":[],"id":2204,"numValue":76.1,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","Saraboji_S1791.csv"],"id":2205,"numValue":-0.8,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":2206,"numValue":53.54,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"... | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16096 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,096 | train | mutant | 310 | 341 | 345 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3K | R3K | 1 | 1 | 0 | 0 | 3 | R | K | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 6,612 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | 1C9O_A:R3K | null | null | 0.88 | 0.19 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":23601,"numValue":0.88,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","potapov_with_uniprot_mapping.csv"],"id":23602,"numValue":0.19,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23603,"numValue":null,"references":[],"strValue":"yes","type":"R... | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16097 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,097 | train | mutant | 310 | 341 | 345 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3K | R3K | 1 | 1 | 0 | 0 | 3 | R | K | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 6,625 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | NaCl | 2 M | 1C9O_A:R3K | null | null | 2.06 | 0.14 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":23640,"numValue":2.06,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":23641,"numValue":0.14,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23642,"numValue":null,"reference... | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:16098 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,098 | train | mutant | 310 | 341 | 345 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3K | R3K | 1 | 1 | 0 | 0 | 3 | R | K | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 5,083,053 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.046063 | 0.054709 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158788,"numValue":-0.0460630619043691,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158789,"numValue":0.0547085286150641,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16099 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,099 | train | mutant | 311 | 341 | 346 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3A | R3A | 1 | 1 | 0 | 0 | 3 | R | A | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 556 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | null | 1C9O_A:R3A | 64.9 | -12 | null | null | null | null | 51.39 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | AUTOMUTE_S1749.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:R3A"... | [{"datasets":[],"id":2208,"numValue":64.9,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","Saraboji_S1791.csv"],"id":2209,"numValue":-12.0,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":2210,"numValue":51.39,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],... | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16100 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,100 | train | mutant | 311 | 341 | 346 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3A | R3A | 1 | 1 | 0 | 0 | 3 | R | A | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 6,626 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | NaCl | 2 M | 1C9O_A:R3A | null | null | 1.15 | 1.05 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":23643,"numValue":1.15,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv"],"id":23644,"numValue":1.05,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23645,"numValue":null,"references":[],"strValue":"yes","type":"REVE... | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:16101 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,101 | train | mutant | 311 | 341 | 346 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3A | R3A | 1 | 1 | 0 | 0 | 3 | R | A | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 5,083,045 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.032005 | 0.034316 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158772,"numValue":-0.0320054936609179,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158773,"numValue":0.0343161038174266,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16102 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,102 | train | mutant | 6,950 | 341 | 7,601 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3E|L66E | R3E|L66E | 2 | 2 | 0 | 0 | 3 | R | E | 4 | CONSERVATION | 1C9O | 231 | null | 3|66 | A|B | E|L | true | false | 123.810613 | 21.635404 | 14,808 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | null | 1C9O_A:R3E 1C9O_A:L66E | 44.6 | -32.3 | null | null | null | null | 36.81 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:R3E 1... | [{"datasets":[],"id":54686,"numValue":44.6,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":54687,"numValue":-32.3,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":54688,"numValue":36.81,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":54689,"numValue":null,"references... | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:16103 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,103 | train | mutant | 6,950 | 341 | 7,601 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3E|L66E | R3E|L66E | 2 | 2 | 0 | 0 | 3 | R | E | 4 | CONSERVATION | 1C9O | 231 | null | 3|66 | A|B | E|L | true | false | 123.810613 | 21.635404 | 15,679 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | null | 1C9O_A:R3E 1C9O_A:L66E | 44.6 | -32.3 | null | null | null | null | 36.81 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:R3E ... | [{"datasets":[],"id":57539,"numValue":44.6,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57540,"numValue":-32.3,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57541,"numValue":36.81,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":57542,"numValue":null,"references... | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:16104 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,104 | train | mutant | 7,317 | 341 | 7,987 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3E|E21A | R3E|E21A | 2 | 2 | 0 | 0 | 3 | R | E | 4 | CONSERVATION | 1C9O | 231 | null | 3|21 | A|B | E|T | true | false | 140.441446 | 22.635404 | 15,677 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | null | 1C9O_A:R3E 1C9O_A:E21A | 60 | -16.9 | null | null | null | null | 49.24 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:R3E ... | [{"datasets":[],"id":57531,"numValue":60.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57532,"numValue":-16.9,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57533,"numValue":49.24,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":57534,"numValue":null,"references... | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20763,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:16105 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,105 | train | mutant | 7,317 | 341 | 7,987 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3E|E21A | R3E|E21A | 2 | 2 | 0 | 0 | 3 | R | E | 4 | CONSERVATION | 1C9O | 231 | null | 3|21 | A|B | E|T | true | false | 140.441446 | 22.635404 | 16,702 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | NaCl | 2 M | 1C9O_A:R3E 1C9O_A:E21A | null | null | 1.1 | 1.1 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":61460,"numValue":1.1,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":61461,"numValue":1.1,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":61462,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20763,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||
fireprotdb:16106 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,106 | train | mutant | 7,318 | 341 | 7,988 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3E|E46A | R3E|E46A | 2 | 2 | 0 | 0 | 3 | R | E | 4 | CONSERVATION | 1C9O | 231 | null | 3|46 | A|B | E | true | false | 98.349516 | 21.027626 | 15,678 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | null | 1C9O_A:R3E 1C9O_A:E46A | 64.6 | -12.3 | null | null | null | null | 52.82 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:R3E ... | [{"datasets":[],"id":57535,"numValue":64.6,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57536,"numValue":-12.3,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57537,"numValue":52.82,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":57538,"numValue":null,"references... | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20788,"numValue":2.0,"position":46,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:16107 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,107 | train | mutant | 7,318 | 341 | 7,988 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3E|E46A | R3E|E46A | 2 | 2 | 0 | 0 | 3 | R | E | 4 | CONSERVATION | 1C9O | 231 | null | 3|46 | A|B | E | true | false | 98.349516 | 21.027626 | 16,703 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | NaCl | 2 M | 1C9O_A:R3E 1C9O_A:E46A | null | null | 1.24 | 0.96 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":61463,"numValue":1.24,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":61464,"numValue":0.96,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":61465,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20788,"numValue":2.0,"position":46,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||
fireprotdb:16108 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,108 | train | mutant | 7,318 | 341 | 7,988 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3E|E46A | R3E|E46A | 2 | 2 | 0 | 0 | 3 | R | E | 4 | CONSERVATION | 1C9O | 231 | null | 3|46 | A|B | E | true | false | 98.349516 | 21.027626 | 16,865 | ProTherm | 7 | CD | GdnHCl | sodium cacodylate-HCl | 100 mM | 25 | 1C9O_A:R3E 1C9O_A:E46A | null | null | 0.76 | 0.43 | null | null | null | 2.47 | 1.63 | null | null | null | null | null | null | null | yes | DG|DDG|M|CM|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","typ... | [{"datasets":[],"id":61966,"numValue":0.76,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":61967,"numValue":0.43,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":61968,"numValue":1.63,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":61969,"numValue":2.47,"references":[],... | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20788,"numValue":2.0,"position":46,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:16109 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,109 | train | mutant | 7,319 | 341 | 7,989 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3E|E46A|L66E | R3E|E46A|L66E | 3 | 3 | 0 | 0 | 3 | R | E | 4 | CONSERVATION | 1C9O | 231 | null | 3|46|66 | A|B | E|L | true | false | 104.038296 | 21.878232 | 15,680 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | null | 1C9O_A:R3E 1C9O_A:E46A 1C9O_A:L66E | 50.3 | -26.6 | null | null | null | null | 40.39 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:R3E ... | [{"datasets":[],"id":57543,"numValue":50.3,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57544,"numValue":-26.6,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57545,"numValue":40.39,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":57546,"numValue":null,"references... | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20788,"numValue":2.0,"position":46,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange... | ||||||||||||||
fireprotdb:16110 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,110 | train | mutant | 4,901,228 | 341 | 4,907,814 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delR3 | delR3 | 1 | 0 | 1 | 0 | 3 | R | - | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 5,083,044 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.044172 | 0.12378 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158770,"numValue":-1.04417204333703,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158771,"numValue":0.123779867058706,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16111 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,111 | train | mutant | 4,901,229 | 341 | 4,907,815 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3C | R3C | 1 | 1 | 0 | 0 | 3 | R | C | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 5,083,046 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.075521 | 0.05936 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158774,"numValue":-0.0755214178574179,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158775,"numValue":0.0593599269082326,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16112 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,112 | train | mutant | 4,901,230 | 341 | 4,907,816 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3D | R3D | 1 | 1 | 0 | 0 | 3 | R | D | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 5,083,047 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.023354 | 0.068758 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158776,"numValue":-0.0233539984674466,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158777,"numValue":0.0687576024476814,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16113 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,113 | train | mutant | 4,901,231 | 341 | 4,907,817 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3F | R3F | 1 | 1 | 0 | 0 | 3 | R | F | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 5,083,049 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.003459 | 0.061665 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158780,"numValue":-0.00345941253505309,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158781,"numValue":0.0616645619313705,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16114 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,114 | train | mutant | 4,901,232 | 341 | 4,907,818 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3G | R3G | 1 | 1 | 0 | 0 | 3 | R | G | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 5,083,050 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.004257 | 0.03106 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158782,"numValue":-0.00425668975569148,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158783,"numValue":0.0310595197928464,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16116 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,116 | train | mutant | 4,901,234 | 341 | 4,907,820 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3I | R3I | 1 | 1 | 0 | 0 | 3 | R | I | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 5,083,052 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.025068 | 0.081344 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158786,"numValue":-0.0250682926846112,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158787,"numValue":0.0813437940985164,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16117 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,117 | train | mutant | 4,901,235 | 341 | 4,907,821 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3M | R3M | 1 | 1 | 0 | 0 | 3 | R | M | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 5,083,055 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.018533 | 0.051116 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158792,"numValue":0.0185329905600464,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158793,"numValue":0.0511161100853889,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16118 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,118 | train | mutant | 4,901,236 | 341 | 4,907,822 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3N | R3N | 1 | 1 | 0 | 0 | 3 | R | N | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 5,083,056 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.060522 | 0.067333 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158794,"numValue":-0.0605219362283944,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158795,"numValue":0.067333114054435,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16120 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,120 | train | mutant | 4,901,238 | 341 | 4,907,824 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3Q | R3Q | 1 | 1 | 0 | 0 | 3 | R | Q | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 5,083,058 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.021033 | 0.040688 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158798,"numValue":-0.0210332993456623,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158799,"numValue":0.0406884531479738,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16121 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,121 | train | mutant | 4,902,472 | 341 | 4,909,058 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3S | R3S | 1 | 1 | 0 | 0 | 3 | R | S | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 5,084,318 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.03899 | 0.030963 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161318,"numValue":-0.0389901163306453,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161319,"numValue":0.030962536502089,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16122 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,122 | train | mutant | 4,902,473 | 341 | 4,909,059 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3T | R3T | 1 | 1 | 0 | 0 | 3 | R | T | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 5,084,319 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.024465 | 0.058959 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161320,"numValue":-0.0244648516358305,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161321,"numValue":0.0589587156710453,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16123 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,123 | train | mutant | 4,902,474 | 341 | 4,909,060 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3V | R3V | 1 | 1 | 0 | 0 | 3 | R | V | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 5,084,320 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.01316 | 0.034091 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161322,"numValue":-0.0131601126954612,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161323,"numValue":0.034090785568849,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16124 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,124 | train | mutant | 4,902,475 | 341 | 4,909,061 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3W | R3W | 1 | 1 | 0 | 0 | 3 | R | W | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 5,084,321 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.116586 | 0.041353 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161324,"numValue":-0.116585640504059,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161325,"numValue":0.0413532104463476,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16125 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,125 | train | mutant | 4,902,476 | 341 | 4,909,062 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R3Y | R3Y | 1 | 1 | 0 | 0 | 3 | R | Y | 4 | CONSERVATION | 1C9O | 231 | null | 3 | A|B | E | true | false | 132.20537 | 19.691364 | 5,084,322 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.026638 | 0.064525 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161326,"numValue":0.0266379507368422,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161327,"numValue":0.0645246828158171,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20745,"numValue":4.0,"position":3,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16126 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,126 | train | mutant | 4,901,239 | 341 | 4,907,825 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delG4 | delG4 | 1 | 0 | 1 | 0 | 4 | G | - | 9 | CONSERVATION | 1C9O | 231 | null | 4 | A|B | E | true | false | 3.749054 | 14.92 | 5,083,059 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.040645 | 0.099573 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158800,"numValue":-1.04064452732251,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158801,"numValue":0.099572574495268,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20746,"numValue":9.0,"position":4,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16127 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,127 | train | mutant | 4,901,240 | 341 | 4,907,826 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G4A | G4A | 1 | 1 | 0 | 0 | 4 | G | A | 9 | CONSERVATION | 1C9O | 231 | null | 4 | A|B | E | true | false | 3.749054 | 14.92 | 5,083,060 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.116996 | 0.024598 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158802,"numValue":-0.116996430923317,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158803,"numValue":0.0245978754135877,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20746,"numValue":9.0,"position":4,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16128 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,128 | train | mutant | 4,901,241 | 341 | 4,907,827 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G4C | G4C | 1 | 1 | 0 | 0 | 4 | G | C | 9 | CONSERVATION | 1C9O | 231 | null | 4 | A|B | E | true | false | 3.749054 | 14.92 | 5,083,061 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.905109 | 0.042003 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158804,"numValue":-0.905108994368412,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158805,"numValue":0.0420033144414544,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20746,"numValue":9.0,"position":4,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16129 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,129 | train | mutant | 4,901,242 | 341 | 4,907,828 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G4D | G4D | 1 | 1 | 0 | 0 | 4 | G | D | 9 | CONSERVATION | 1C9O | 231 | null | 4 | A|B | E | true | false | 3.749054 | 14.92 | 5,083,062 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.891219 | 0.037807 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158806,"numValue":-0.891218706148503,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158807,"numValue":0.0378068798749658,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20746,"numValue":9.0,"position":4,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16130 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,130 | train | mutant | 4,901,243 | 341 | 4,907,829 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G4E | G4E | 1 | 1 | 0 | 0 | 4 | G | E | 9 | CONSERVATION | 1C9O | 231 | null | 4 | A|B | E | true | false | 3.749054 | 14.92 | 5,083,063 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.71682 | 0.047839 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158808,"numValue":-0.716819619435783,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158809,"numValue":0.0478393955519516,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20746,"numValue":9.0,"position":4,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16131 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,131 | train | mutant | 4,901,244 | 341 | 4,907,830 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G4F | G4F | 1 | 1 | 0 | 0 | 4 | G | F | 9 | CONSERVATION | 1C9O | 231 | null | 4 | A|B | E | true | false | 3.749054 | 14.92 | 5,083,064 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.866337 | 0.035319 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158810,"numValue":-0.866337492044437,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158811,"numValue":0.0353186399103257,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20746,"numValue":9.0,"position":4,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16132 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,132 | train | mutant | 4,902,458 | 341 | 4,909,044 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G4H | G4H | 1 | 1 | 0 | 0 | 4 | G | H | 9 | CONSERVATION | 1C9O | 231 | null | 4 | A|B | E | true | false | 3.749054 | 14.92 | 5,084,304 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.409012 | 0.029454 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161290,"numValue":-0.409012105755065,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161291,"numValue":0.0294537323379403,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20746,"numValue":9.0,"position":4,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16134 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,134 | train | mutant | 4,902,460 | 341 | 4,909,046 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G4K | G4K | 1 | 1 | 0 | 0 | 4 | G | K | 9 | CONSERVATION | 1C9O | 231 | null | 4 | A|B | E | true | false | 3.749054 | 14.92 | 5,084,306 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.654467 | 0.041179 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161294,"numValue":-0.654467205841343,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161295,"numValue":0.041179190614628,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20746,"numValue":9.0,"position":4,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16136 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,136 | train | mutant | 4,902,462 | 341 | 4,909,048 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G4M | G4M | 1 | 1 | 0 | 0 | 4 | G | M | 9 | CONSERVATION | 1C9O | 231 | null | 4 | A|B | E | true | false | 3.749054 | 14.92 | 5,084,308 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.996525 | 0.065961 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161298,"numValue":-0.996524563378354,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161299,"numValue":0.0659609080781852,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20746,"numValue":9.0,"position":4,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16137 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,137 | train | mutant | 4,902,463 | 341 | 4,909,049 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G4N | G4N | 1 | 1 | 0 | 0 | 4 | G | N | 9 | CONSERVATION | 1C9O | 231 | null | 4 | A|B | E | true | false | 3.749054 | 14.92 | 5,084,309 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.368437 | 0.029403 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161300,"numValue":-0.368436919321827,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161301,"numValue":0.0294025584030275,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20746,"numValue":9.0,"position":4,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16138 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,138 | train | mutant | 4,902,464 | 341 | 4,909,050 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G4P | G4P | 1 | 1 | 0 | 0 | 4 | G | P | 9 | CONSERVATION | 1C9O | 231 | null | 4 | A|B | E | true | false | 3.749054 | 14.92 | 5,084,310 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.571271 | 0.035433 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161302,"numValue":-0.571270942566456,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161303,"numValue":0.0354328669143532,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20746,"numValue":9.0,"position":4,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16139 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,139 | train | mutant | 4,902,465 | 341 | 4,909,051 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G4Q | G4Q | 1 | 1 | 0 | 0 | 4 | G | Q | 9 | CONSERVATION | 1C9O | 231 | null | 4 | A|B | E | true | false | 3.749054 | 14.92 | 5,084,311 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.427889 | 0.035045 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161304,"numValue":-0.427888903592413,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161305,"numValue":0.0350451471489441,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20746,"numValue":9.0,"position":4,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16140 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,140 | train | mutant | 4,902,466 | 341 | 4,909,052 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G4R | G4R | 1 | 1 | 0 | 0 | 4 | G | R | 9 | CONSERVATION | 1C9O | 231 | null | 4 | A|B | E | true | false | 3.749054 | 14.92 | 5,084,312 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.537256 | 0.023954 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161306,"numValue":-0.537255717538362,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161307,"numValue":0.0239540014434541,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20746,"numValue":9.0,"position":4,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16141 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,141 | train | mutant | 4,902,467 | 341 | 4,909,053 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G4S | G4S | 1 | 1 | 0 | 0 | 4 | G | S | 9 | CONSERVATION | 1C9O | 231 | null | 4 | A|B | E | true | false | 3.749054 | 14.92 | 5,084,313 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.109018 | 0.021214 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161308,"numValue":-0.109018323776422,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161309,"numValue":0.0212140886241177,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20746,"numValue":9.0,"position":4,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16142 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,142 | train | mutant | 4,902,468 | 341 | 4,909,054 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G4T | G4T | 1 | 1 | 0 | 0 | 4 | G | T | 9 | CONSERVATION | 1C9O | 231 | null | 4 | A|B | E | true | false | 3.749054 | 14.92 | 5,084,314 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.770379 | 0.039469 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161310,"numValue":-0.770379280467474,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161311,"numValue":0.0394686545666669,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20746,"numValue":9.0,"position":4,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16144 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,144 | train | mutant | 4,902,470 | 341 | 4,909,056 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G4W | G4W | 1 | 1 | 0 | 0 | 4 | G | W | 9 | CONSERVATION | 1C9O | 231 | null | 4 | A|B | E | true | false | 3.749054 | 14.92 | 5,084,316 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.054922 | 0.067058 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161314,"numValue":-1.05492190104268,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161315,"numValue":0.0670581867868275,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20746,"numValue":9.0,"position":4,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16145 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,145 | train | mutant | 4,902,471 | 341 | 4,909,057 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G4Y | G4Y | 1 | 1 | 0 | 0 | 4 | G | Y | 9 | CONSERVATION | 1C9O | 231 | null | 4 | A|B | E | true | false | 3.749054 | 14.92 | 5,084,317 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.809919 | 0.04148 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161316,"numValue":-0.809919073501984,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161317,"numValue":0.0414801761027703,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20746,"numValue":9.0,"position":4,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16146 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,146 | train | mutant | 4,901,245 | 341 | 4,907,831 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delK5 | delK5 | 1 | 0 | 1 | 0 | 5 | K | - | 7 | CONSERVATION | 1C9O | 231 | null | 5 | A|B | E | true | false | 69.955167 | 20.854445 | 5,083,065 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.015105 | 0.08957 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158812,"numValue":-1.01510455476429,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158813,"numValue":0.0895702130875863,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20747,"numValue":7.0,"position":5,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16147 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,147 | train | mutant | 4,901,246 | 341 | 4,907,832 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K5A | K5A | 1 | 1 | 0 | 0 | 5 | K | A | 7 | CONSERVATION | 1C9O | 231 | null | 5 | A|B | E | true | false | 69.955167 | 20.854445 | 5,083,066 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.041967 | 0.042212 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158814,"numValue":-0.0419670131351407,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158815,"numValue":0.0422117090731925,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20747,"numValue":7.0,"position":5,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16148 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,148 | train | mutant | 4,901,247 | 341 | 4,907,833 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K5C | K5C | 1 | 1 | 0 | 0 | 5 | K | C | 7 | CONSERVATION | 1C9O | 231 | null | 5 | A|B | E | true | false | 69.955167 | 20.854445 | 5,083,067 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.002785 | 0.048972 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158816,"numValue":-0.00278543171730891,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158817,"numValue":0.0489715766269516,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20747,"numValue":7.0,"position":5,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16149 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,149 | train | mutant | 4,901,248 | 341 | 4,907,834 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K5D | K5D | 1 | 1 | 0 | 0 | 5 | K | D | 7 | CONSERVATION | 1C9O | 231 | null | 5 | A|B | E | true | false | 69.955167 | 20.854445 | 5,083,068 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.156184 | 0.081642 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158818,"numValue":-0.156183940052827,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158819,"numValue":0.0816415430560827,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20747,"numValue":7.0,"position":5,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16150 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,150 | train | mutant | 4,901,249 | 341 | 4,907,835 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K5E | K5E | 1 | 1 | 0 | 0 | 5 | K | E | 7 | CONSERVATION | 1C9O | 231 | null | 5 | A|B | E | true | false | 69.955167 | 20.854445 | 5,083,069 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.064651 | 0.056356 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158820,"numValue":-0.0646511801830174,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158821,"numValue":0.0563558396902719,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20747,"numValue":7.0,"position":5,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16151 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,151 | train | mutant | 4,901,250 | 341 | 4,907,836 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K5F | K5F | 1 | 1 | 0 | 0 | 5 | K | F | 7 | CONSERVATION | 1C9O | 231 | null | 5 | A|B | E | true | false | 69.955167 | 20.854445 | 5,083,070 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.008493 | 0.06121 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158822,"numValue":-0.00849322529167916,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158823,"numValue":0.0612102028312817,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20747,"numValue":7.0,"position":5,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16152 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,152 | train | mutant | 4,901,251 | 341 | 4,907,837 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K5G | K5G | 1 | 1 | 0 | 0 | 5 | K | G | 7 | CONSERVATION | 1C9O | 231 | null | 5 | A|B | E | true | false | 69.955167 | 20.854445 | 5,083,071 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.222142 | 0.032883 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158824,"numValue":-0.222141587889589,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158825,"numValue":0.0328831091579229,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20747,"numValue":7.0,"position":5,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16153 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,153 | train | mutant | 4,901,252 | 341 | 4,907,838 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K5H | K5H | 1 | 1 | 0 | 0 | 5 | K | H | 7 | CONSERVATION | 1C9O | 231 | null | 5 | A|B | E | true | false | 69.955167 | 20.854445 | 5,083,072 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.005231 | 0.064673 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158826,"numValue":0.00523061278432261,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158827,"numValue":0.0646730534391077,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20747,"numValue":7.0,"position":5,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16154 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,154 | train | mutant | 4,901,253 | 341 | 4,907,839 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K5I | K5I | 1 | 1 | 0 | 0 | 5 | K | I | 7 | CONSERVATION | 1C9O | 231 | null | 5 | A|B | E | true | false | 69.955167 | 20.854445 | 5,083,073 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.036532 | 0.049606 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158828,"numValue":-0.0365324870691082,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158829,"numValue":0.0496057943547625,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20747,"numValue":7.0,"position":5,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16156 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,156 | train | mutant | 4,902,448 | 341 | 4,909,034 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K5M | K5M | 1 | 1 | 0 | 0 | 5 | K | M | 7 | CONSERVATION | 1C9O | 231 | null | 5 | A|B | E | true | false | 69.955167 | 20.854445 | 5,084,294 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.069319 | 0.038936 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161270,"numValue":-0.069319253129135,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161271,"numValue":0.0389362927086125,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20747,"numValue":7.0,"position":5,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16157 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,157 | train | mutant | 4,902,449 | 341 | 4,909,035 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K5N | K5N | 1 | 1 | 0 | 0 | 5 | K | N | 7 | CONSERVATION | 1C9O | 231 | null | 5 | A|B | E | true | false | 69.955167 | 20.854445 | 5,084,295 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.028697 | 0.062512 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161272,"numValue":-0.0286966450024761,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161273,"numValue":0.0625124618097357,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20747,"numValue":7.0,"position":5,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16158 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,158 | train | mutant | 4,902,450 | 341 | 4,909,036 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K5P | K5P | 1 | 1 | 0 | 0 | 5 | K | P | 7 | CONSERVATION | 1C9O | 231 | null | 5 | A|B | E | true | false | 69.955167 | 20.854445 | 5,084,296 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.220251 | 0.041017 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161274,"numValue":-0.220250647864432,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161275,"numValue":0.0410171743990556,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20747,"numValue":7.0,"position":5,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16159 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,159 | train | mutant | 4,902,451 | 341 | 4,909,037 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K5Q | K5Q | 1 | 1 | 0 | 0 | 5 | K | Q | 7 | CONSERVATION | 1C9O | 231 | null | 5 | A|B | E | true | false | 69.955167 | 20.854445 | 5,084,297 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.055555 | 0.044504 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161276,"numValue":-0.0555551066137254,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161277,"numValue":0.044503901829519,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20747,"numValue":7.0,"position":5,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16160 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,160 | train | mutant | 4,902,452 | 341 | 4,909,038 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K5R | K5R | 1 | 1 | 0 | 0 | 5 | K | R | 7 | CONSERVATION | 1C9O | 231 | null | 5 | A|B | E | true | false | 69.955167 | 20.854445 | 5,084,298 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.035403 | 0.025772 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161278,"numValue":-0.0354032579945237,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161279,"numValue":0.0257718112896449,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20747,"numValue":7.0,"position":5,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16161 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,161 | train | mutant | 4,902,453 | 341 | 4,909,039 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K5S | K5S | 1 | 1 | 0 | 0 | 5 | K | S | 7 | CONSERVATION | 1C9O | 231 | null | 5 | A|B | E | true | false | 69.955167 | 20.854445 | 5,084,299 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.02712 | 0.033802 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161280,"numValue":-0.0271204664673996,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161281,"numValue":0.0338019222510874,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20747,"numValue":7.0,"position":5,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16163 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,163 | train | mutant | 4,902,455 | 341 | 4,909,041 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K5V | K5V | 1 | 1 | 0 | 0 | 5 | K | V | 7 | CONSERVATION | 1C9O | 231 | null | 5 | A|B | E | true | false | 69.955167 | 20.854445 | 5,084,301 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.030356 | 0.039104 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161284,"numValue":-0.0303564042722068,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161285,"numValue":0.0391036912863882,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20747,"numValue":7.0,"position":5,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16164 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,164 | train | mutant | 4,902,456 | 341 | 4,909,042 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K5W | K5W | 1 | 1 | 0 | 0 | 5 | K | W | 7 | CONSERVATION | 1C9O | 231 | null | 5 | A|B | E | true | false | 69.955167 | 20.854445 | 5,084,302 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.051784 | 0.029981 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161286,"numValue":-0.0517844892155979,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161287,"numValue":0.0299808955928535,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20747,"numValue":7.0,"position":5,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16165 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,165 | train | mutant | 4,902,457 | 341 | 4,909,043 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K5Y | K5Y | 1 | 1 | 0 | 0 | 5 | K | Y | 7 | CONSERVATION | 1C9O | 231 | null | 5 | A|B | E | true | false | 69.955167 | 20.854445 | 5,084,303 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.071623 | 0.061121 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12161288,"numValue":-0.071622761887054,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12161289,"numValue":0.0611214057103511,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20747,"numValue":7.0,"position":5,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16166 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,166 | train | mutant | 4,901,254 | 341 | 4,907,840 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delV6 | delV6 | 1 | 0 | 1 | 0 | 6 | V | - | 9 | CONSERVATION | 1C9O | 231 | null | 6 | A|B | E | false | false | 0.985203 | 12.711429 | 5,083,074 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.203729 | 0.183436 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158830,"numValue":-1.20372908844289,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158831,"numValue":0.183436416659287,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20748,"numValue":9.0,"position":6,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16167 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,167 | train | mutant | 4,901,255 | 341 | 4,907,841 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V6A | V6A | 1 | 1 | 0 | 0 | 6 | V | A | 9 | CONSERVATION | 1C9O | 231 | null | 6 | A|B | E | false | false | 0.985203 | 12.711429 | 5,083,075 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.088118 | 0.034888 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158832,"numValue":-0.0881178051723383,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158833,"numValue":0.0348877426930569,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20748,"numValue":9.0,"position":6,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16168 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,168 | train | mutant | 4,901,256 | 341 | 4,907,842 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V6C | V6C | 1 | 1 | 0 | 0 | 6 | V | C | 9 | CONSERVATION | 1C9O | 231 | null | 6 | A|B | E | false | false | 0.985203 | 12.711429 | 5,083,076 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.05838 | 0.059214 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158834,"numValue":-0.0583802539992741,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158835,"numValue":0.0592140518515583,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20748,"numValue":9.0,"position":6,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16169 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,169 | train | mutant | 4,901,257 | 341 | 4,907,843 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V6D | V6D | 1 | 1 | 0 | 0 | 6 | V | D | 9 | CONSERVATION | 1C9O | 231 | null | 6 | A|B | E | false | false | 0.985203 | 12.711429 | 5,083,077 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.087387 | 0.106368 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158836,"numValue":-1.08738651968388,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158837,"numValue":0.106368221716713,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20748,"numValue":9.0,"position":6,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16170 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,170 | train | mutant | 4,901,258 | 341 | 4,907,844 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V6E | V6E | 1 | 1 | 0 | 0 | 6 | V | E | 9 | CONSERVATION | 1C9O | 231 | null | 6 | A|B | E | false | false | 0.985203 | 12.711429 | 5,083,078 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.019533 | 0.090998 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158838,"numValue":-1.01953266208628,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158839,"numValue":0.0909980802764889,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20748,"numValue":9.0,"position":6,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16171 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,171 | train | mutant | 4,901,259 | 341 | 4,907,845 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V6F | V6F | 1 | 1 | 0 | 0 | 6 | V | F | 9 | CONSERVATION | 1C9O | 231 | null | 6 | A|B | E | false | false | 0.985203 | 12.711429 | 5,083,079 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.621612 | 0.051499 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158840,"numValue":-0.621611678325856,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158841,"numValue":0.0514994848381383,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20748,"numValue":9.0,"position":6,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16172 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,172 | train | mutant | 4,901,260 | 341 | 4,907,846 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V6G | V6G | 1 | 1 | 0 | 0 | 6 | V | G | 9 | CONSERVATION | 1C9O | 231 | null | 6 | A|B | E | false | false | 0.985203 | 12.711429 | 5,083,080 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.451778 | 0.025727 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158842,"numValue":-0.451778174424348,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158843,"numValue":0.0257272348978293,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20748,"numValue":9.0,"position":6,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16173 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,173 | train | mutant | 4,901,261 | 341 | 4,907,847 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V6H | V6H | 1 | 1 | 0 | 0 | 6 | V | H | 9 | CONSERVATION | 1C9O | 231 | null | 6 | A|B | E | false | false | 0.985203 | 12.711429 | 5,083,081 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.862961 | 0.083837 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158844,"numValue":-0.862961482412688,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158845,"numValue":0.0838372267385861,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20748,"numValue":9.0,"position":6,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16174 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,174 | train | mutant | 4,901,262 | 341 | 4,907,848 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V6I | V6I | 1 | 1 | 0 | 0 | 6 | V | I | 9 | CONSERVATION | 1C9O | 231 | null | 6 | A|B | E | false | false | 0.985203 | 12.711429 | 5,083,082 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.017288 | 0.039954 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158846,"numValue":-0.0172881711077486,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158847,"numValue":0.0399543771892419,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20748,"numValue":9.0,"position":6,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16176 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,176 | train | mutant | 4,901,264 | 341 | 4,907,850 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V6L | V6L | 1 | 1 | 0 | 0 | 6 | V | L | 9 | CONSERVATION | 1C9O | 231 | null | 6 | A|B | E | false | false | 0.985203 | 12.711429 | 5,083,084 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.158145 | 0.030495 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158850,"numValue":-0.158145419846948,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158851,"numValue":0.030494869689284,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20748,"numValue":9.0,"position":6,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16177 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,177 | train | mutant | 4,901,265 | 341 | 4,907,851 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V6M | V6M | 1 | 1 | 0 | 0 | 6 | V | M | 9 | CONSERVATION | 1C9O | 231 | null | 6 | A|B | E | false | false | 0.985203 | 12.711429 | 5,083,085 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.103884 | 0.058739 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158852,"numValue":-0.103884332692445,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158853,"numValue":0.0587385545316272,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20748,"numValue":9.0,"position":6,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16179 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,179 | train | mutant | 4,901,267 | 341 | 4,907,853 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V6P | V6P | 1 | 1 | 0 | 0 | 6 | V | P | 9 | CONSERVATION | 1C9O | 231 | null | 6 | A|B | E | false | false | 0.985203 | 12.711429 | 5,083,087 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.801067 | 0.081078 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12158856,"numValue":-0.801067458762277,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12158857,"numValue":0.0810784697238266,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20748,"numValue":9.0,"position":6,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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