row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:16502 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,502 | train | mutant | 4,902,291 | 341 | 4,908,877 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | E21H | E21H | 1 | 1 | 0 | 0 | 21 | E | H | 4 | CONSERVATION | 1C9O | 231 | null | 21 | A|B | T | true | false | 148.677523 | 25.579444 | 5,084,134 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.026787 | 0.051551 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160950,"numValue":0.0267867362999502,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160951,"numValue":0.0515509433032117,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20763,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16503 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,503 | train | mutant | 4,902,292 | 341 | 4,908,878 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | E21I | E21I | 1 | 1 | 0 | 0 | 21 | E | I | 4 | CONSERVATION | 1C9O | 231 | null | 21 | A|B | T | true | false | 148.677523 | 25.579444 | 5,084,135 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.034374 | 0.069142 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160952,"numValue":0.0343736144761227,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160953,"numValue":0.0691420145499744,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20763,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16505 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,505 | train | mutant | 4,902,294 | 341 | 4,908,880 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | E21M | E21M | 1 | 1 | 0 | 0 | 21 | E | M | 4 | CONSERVATION | 1C9O | 231 | null | 21 | A|B | T | true | false | 148.677523 | 25.579444 | 5,084,138 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.050767 | 0.069121 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160958,"numValue":-0.0507667011205522,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160959,"numValue":0.0691212675591027,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20763,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16506 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,506 | train | mutant | 4,902,295 | 341 | 4,908,881 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | E21N | E21N | 1 | 1 | 0 | 0 | 21 | E | N | 4 | CONSERVATION | 1C9O | 231 | null | 21 | A|B | T | true | false | 148.677523 | 25.579444 | 5,084,139 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.022173 | 0.08589 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160960,"numValue":0.0221726055300987,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160961,"numValue":0.0858902896781262,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20763,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16508 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,508 | train | mutant | 4,902,297 | 341 | 4,908,883 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | E21Q | E21Q | 1 | 1 | 0 | 0 | 21 | E | Q | 4 | CONSERVATION | 1C9O | 231 | null | 21 | A|B | T | true | false | 148.677523 | 25.579444 | 5,084,141 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.006828 | 0.066369 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160964,"numValue":-0.00682813108143861,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160965,"numValue":0.0663689717500718,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20763,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16509 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,509 | train | mutant | 4,902,298 | 341 | 4,908,884 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | E21R | E21R | 1 | 1 | 0 | 0 | 21 | E | R | 4 | CONSERVATION | 1C9O | 231 | null | 21 | A|B | T | true | false | 148.677523 | 25.579444 | 5,084,142 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.010688 | 0.03624 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160966,"numValue":0.0106876641547302,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160967,"numValue":0.0362402805219604,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20763,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16510 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,510 | train | mutant | 4,902,299 | 341 | 4,908,885 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | E21S | E21S | 1 | 1 | 0 | 0 | 21 | E | S | 4 | CONSERVATION | 1C9O | 231 | null | 21 | A|B | T | true | false | 148.677523 | 25.579444 | 5,084,143 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.008738 | 0.035598 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160968,"numValue":-0.00873803978396441,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160969,"numValue":0.0355977936363594,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20763,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16511 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,511 | train | mutant | 4,902,300 | 341 | 4,908,886 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | E21T | E21T | 1 | 1 | 0 | 0 | 21 | E | T | 4 | CONSERVATION | 1C9O | 231 | null | 21 | A|B | T | true | false | 148.677523 | 25.579444 | 5,084,144 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.0137 | 0.054559 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160970,"numValue":0.0136995344581235,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160971,"numValue":0.0545592154856168,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20763,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16512 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,512 | train | mutant | 4,902,301 | 341 | 4,908,887 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | E21V | E21V | 1 | 1 | 0 | 0 | 21 | E | V | 4 | CONSERVATION | 1C9O | 231 | null | 21 | A|B | T | true | false | 148.677523 | 25.579444 | 5,084,145 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.012858 | 0.034839 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160972,"numValue":0.0128577993999029,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160973,"numValue":0.0348388924211217,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20763,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16513 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,513 | train | mutant | 4,902,302 | 341 | 4,908,888 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | E21W | E21W | 1 | 1 | 0 | 0 | 21 | E | W | 4 | CONSERVATION | 1C9O | 231 | null | 21 | A|B | T | true | false | 148.677523 | 25.579444 | 5,084,146 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.033471 | 0.043944 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160974,"numValue":-0.0334714167587906,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160975,"numValue":0.0439439464736053,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20763,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16514 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,514 | train | mutant | 4,902,303 | 341 | 4,908,889 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | E21Y | E21Y | 1 | 1 | 0 | 0 | 21 | E | Y | 4 | CONSERVATION | 1C9O | 231 | null | 21 | A|B | T | true | false | 148.677523 | 25.579444 | 5,084,147 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.022445 | 0.041508 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160976,"numValue":-0.0224446874961013,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160977,"numValue":0.0415077043958011,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20763,"numValue":4.0,"position":21,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16515 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,515 | train | mutant | 4,901,410 | 341 | 4,907,996 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delG22 | delG22 | 1 | 0 | 1 | 0 | 22 | G | - | 4 | CONSERVATION | 1C9O | 231 | null | 22 | A|B | T | false | false | 94.832041 | 26.795 | 5,083,233 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.988771 | 0.074528 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159148,"numValue":-0.988770642287107,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159149,"numValue":0.0745278741031337,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20764,"numValue":4.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16516 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,516 | train | mutant | 4,901,410 | 341 | 4,907,996 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delG22 | delG22 | 1 | 0 | 1 | 0 | 22 | G | - | 4 | CONSERVATION | 1C9O | 231 | null | 22 | A|B | T | false | false | 94.832041 | 26.795 | 5,083,239 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.968779 | 0.079797 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159160,"numValue":-0.968779256823018,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159161,"numValue":0.0797971355675945,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20764,"numValue":4.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16518 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,518 | train | mutant | 4,901,412 | 341 | 4,907,998 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G22C | G22C | 1 | 1 | 0 | 0 | 22 | G | C | 4 | CONSERVATION | 1C9O | 231 | null | 22 | A|B | T | false | false | 94.832041 | 26.795 | 5,083,235 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.01972 | 0.057358 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159152,"numValue":0.0197197184379039,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159153,"numValue":0.0573576644577696,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20764,"numValue":4.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16520 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,520 | train | mutant | 4,901,414 | 341 | 4,908,000 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G22E | G22E | 1 | 1 | 0 | 0 | 22 | G | E | 4 | CONSERVATION | 1C9O | 231 | null | 22 | A|B | T | false | false | 94.832041 | 26.795 | 5,083,237 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.012745 | 0.05444 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159156,"numValue":-0.0127451728780286,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159157,"numValue":0.0544399854929334,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20764,"numValue":4.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16521 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,521 | train | mutant | 4,901,415 | 341 | 4,908,001 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G22F | G22F | 1 | 1 | 0 | 0 | 22 | G | F | 4 | CONSERVATION | 1C9O | 231 | null | 22 | A|B | T | false | false | 94.832041 | 26.795 | 5,083,238 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.015516 | 0.060132 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159158,"numValue":-0.015516378087311,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159159,"numValue":0.0601323670169419,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20764,"numValue":4.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16523 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,523 | train | mutant | 4,902,276 | 341 | 4,908,862 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G22I | G22I | 1 | 1 | 0 | 0 | 22 | G | I | 4 | CONSERVATION | 1C9O | 231 | null | 22 | A|B | T | false | false | 94.832041 | 26.795 | 5,084,119 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.027278 | 0.058705 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160920,"numValue":-0.0272781435980241,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160921,"numValue":0.0587052052257289,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20764,"numValue":4.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16525 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,525 | train | mutant | 4,902,278 | 341 | 4,908,864 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G22L | G22L | 1 | 1 | 0 | 0 | 22 | G | L | 4 | CONSERVATION | 1C9O | 231 | null | 22 | A|B | T | false | false | 94.832041 | 26.795 | 5,084,121 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.012114 | 0.02775 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160924,"numValue":-0.0121138715843631,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160925,"numValue":0.0277498886764632,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20764,"numValue":4.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16526 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,526 | train | mutant | 4,902,279 | 341 | 4,908,865 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G22M | G22M | 1 | 1 | 0 | 0 | 22 | G | M | 4 | CONSERVATION | 1C9O | 231 | null | 22 | A|B | T | false | false | 94.832041 | 26.795 | 5,084,122 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.009639 | 0.047364 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160926,"numValue":-0.00963905195896115,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160927,"numValue":0.0473638270994803,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20764,"numValue":4.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16528 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,528 | train | mutant | 4,902,281 | 341 | 4,908,867 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G22P | G22P | 1 | 1 | 0 | 0 | 22 | G | P | 4 | CONSERVATION | 1C9O | 231 | null | 22 | A|B | T | false | false | 94.832041 | 26.795 | 5,084,124 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.032185 | 0.047377 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160930,"numValue":0.0321845105535816,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160931,"numValue":0.0473770221856746,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20764,"numValue":4.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16529 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,529 | train | mutant | 4,902,282 | 341 | 4,908,868 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G22Q | G22Q | 1 | 1 | 0 | 0 | 22 | G | Q | 4 | CONSERVATION | 1C9O | 231 | null | 22 | A|B | T | false | false | 94.832041 | 26.795 | 5,084,125 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.035413 | 0.058472 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160932,"numValue":-0.0354133351043756,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160933,"numValue":0.0584717719398647,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20764,"numValue":4.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16530 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,530 | train | mutant | 4,902,283 | 341 | 4,908,869 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G22R | G22R | 1 | 1 | 0 | 0 | 22 | G | R | 4 | CONSERVATION | 1C9O | 231 | null | 22 | A|B | T | false | false | 94.832041 | 26.795 | 5,084,126 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.010823 | 0.034012 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160934,"numValue":-0.0108228159809798,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160935,"numValue":0.0340121781842922,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20764,"numValue":4.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16531 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,531 | train | mutant | 4,902,284 | 341 | 4,908,870 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G22S | G22S | 1 | 1 | 0 | 0 | 22 | G | S | 4 | CONSERVATION | 1C9O | 231 | null | 22 | A|B | T | false | false | 94.832041 | 26.795 | 5,084,127 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.01076 | 0.035212 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160936,"numValue":0.010759982237197,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160937,"numValue":0.03521173363022,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20764,"numValue":4.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16532 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,532 | train | mutant | 4,902,285 | 341 | 4,908,871 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G22T | G22T | 1 | 1 | 0 | 0 | 22 | G | T | 4 | CONSERVATION | 1C9O | 231 | null | 22 | A|B | T | false | false | 94.832041 | 26.795 | 5,084,128 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.024575 | 0.047977 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160938,"numValue":0.0245745143018663,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160939,"numValue":0.0479771852098976,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20764,"numValue":4.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16533 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,533 | train | mutant | 4,902,286 | 341 | 4,908,872 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G22V | G22V | 1 | 1 | 0 | 0 | 22 | G | V | 4 | CONSERVATION | 1C9O | 231 | null | 22 | A|B | T | false | false | 94.832041 | 26.795 | 5,084,129 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.020212 | 0.032777 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160940,"numValue":-0.0202117185071457,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160941,"numValue":0.0327768786369484,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20764,"numValue":4.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16534 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,534 | train | mutant | 4,902,287 | 341 | 4,908,873 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G22W | G22W | 1 | 1 | 0 | 0 | 22 | G | W | 4 | CONSERVATION | 1C9O | 231 | null | 22 | A|B | T | false | false | 94.832041 | 26.795 | 5,084,130 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.018567 | 0.036457 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160942,"numValue":-0.0185667785166089,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160943,"numValue":0.0364571162151274,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20764,"numValue":4.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16535 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,535 | train | mutant | 4,902,288 | 341 | 4,908,874 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G22Y | G22Y | 1 | 1 | 0 | 0 | 22 | G | Y | 4 | CONSERVATION | 1C9O | 231 | null | 22 | A|B | T | false | false | 94.832041 | 26.795 | 5,084,131 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.062507 | 0.061515 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160944,"numValue":-0.062507126869226,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160945,"numValue":0.0615151835970947,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20764,"numValue":4.0,"position":22,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16536 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,536 | train | mutant | 315 | 341 | 350 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23Q | G23Q | 1 | 1 | 0 | 0 | 23 | G | Q | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 560 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | null | 1C9O_A:G23Q | 74.7 | -2.2 | null | null | null | null | 59.51 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | AUTOMUTE_S1749.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:G23Q... | [{"datasets":[],"id":2224,"numValue":74.7,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","Saraboji_S1791.csv"],"id":2225,"numValue":-2.2,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":2226,"numValue":59.51,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"... | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16537 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,537 | train | mutant | 315 | 341 | 350 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23Q | G23Q | 1 | 1 | 0 | 0 | 23 | G | Q | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 4,178 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | null | 1C9O_A:G23Q | 74.7 | -2.2 | null | null | null | null | 59.51 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | AUTOMUTE_S1749.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:G23Q"... | [{"datasets":[],"id":15494,"numValue":74.7,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","Saraboji_S1791.csv"],"id":15495,"numValue":-2.2,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":15496,"numValue":59.51,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[... | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16538 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,538 | train | mutant | 315 | 341 | 350 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23Q | G23Q | 1 | 1 | 0 | 0 | 23 | G | Q | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 6,616 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | 1C9O_A:G23Q | null | null | 0.79 | 0.29 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":23613,"numValue":0.79,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","potapov_with_uniprot_mapping.csv"],"id":23614,"numValue":0.29,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23615,"numValue":null,"references":[],"strValue":"yes","type":"R... | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16539 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,539 | train | mutant | 315 | 341 | 350 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23Q | G23Q | 1 | 1 | 0 | 0 | 23 | G | Q | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 6,630 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | NaCl | 2 M | 1C9O_A:G23Q | null | null | 1.89 | 0.31 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":23655,"numValue":1.89,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","potapov_with_uniprot_mapping.csv"],"id":23656,"numValue":0.31,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23657,"numValue":null,"references":[],"strValue":"yes","type":"R... | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:16540 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,540 | train | mutant | 315 | 341 | 350 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23Q | G23Q | 1 | 1 | 0 | 0 | 23 | G | Q | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 6,650 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | 70 | 1C9O_A:G23Q | null | null | 0.79 | 0.29 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","typ... | [{"datasets":[],"id":23711,"numValue":0.79,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","potapov_with_uniprot_mapping.csv"],"id":23712,"numValue":0.29,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23713,"numValue":null,"references":[],"strValue":"yes","type":"R... | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16541 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,541 | train | mutant | 315 | 341 | 350 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23Q | G23Q | 1 | 1 | 0 | 0 | 23 | G | Q | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 6,660 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | 70 | NaCl | 2 M | 1C9O_A:G23Q | null | null | 1.89 | 0.31 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","typ... | [{"datasets":[],"id":23741,"numValue":1.89,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","potapov_with_uniprot_mapping.csv"],"id":23742,"numValue":0.31,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23743,"numValue":null,"references":[],"strValue":"yes","type":"R... | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:16542 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,542 | train | mutant | 315 | 341 | 350 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23Q | G23Q | 1 | 1 | 0 | 0 | 23 | G | Q | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 8,802 | ProTherm | 7 | CD | GdnHCl | sodium cacodylate-HCl | 100 mM | 25 | 1C9O_A:G23Q | null | null | 1.2 | 0 | null | null | null | 2.62 | 1.89 | null | null | null | null | null | null | null | yes | DG|DDG|M|CM|REVERSIBILITY | khan_protherm_data_mapped.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","typ... | [{"datasets":[],"id":29764,"numValue":1.2,"references":[],"strValue":null,"type":"DG"},{"datasets":["khan_protherm_data_mapped.csv"],"id":29765,"numValue":0.0,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":29766,"numValue":1.89,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":29767,"nu... | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16543 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,543 | train | mutant | 315 | 341 | 350 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23Q | G23Q | 1 | 1 | 0 | 0 | 23 | G | Q | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 5,084,111 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.01179 | 0.054676 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160904,"numValue":0.0117896257555977,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160905,"numValue":0.0546758491405855,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16544 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,544 | train | mutant | 7,320 | 341 | 7,990 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23Q|S24D | G23Q|S24D | 2 | 2 | 0 | 0 | 23 | G | Q | 4 | CONSERVATION | 1C9O | 231 | null | 23|24 | A|B | E|S|L | false | false | 68.854291 | 17.0275 | 15,681 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | null | 1C9O_A:G23Q 1C9O_A:S24D | 75.9 | -1 | null | null | null | null | 59.51 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:G23Q... | [{"datasets":[],"id":57547,"numValue":75.9,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57548,"numValue":-1.0,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57549,"numValue":59.51,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":57550,"numValue":null,"references"... | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:16545 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,545 | train | mutant | 7,320 | 341 | 7,990 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23Q|S24D | G23Q|S24D | 2 | 2 | 0 | 0 | 23 | G | Q | 4 | CONSERVATION | 1C9O | 231 | null | 23|24 | A|B | E|S|L | false | false | 68.854291 | 17.0275 | 16,698 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | 1C9O_A:G23Q 1C9O_A:S24D | null | null | 0.96 | 0.12 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":61448,"numValue":0.96,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":61449,"numValue":0.12,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":61450,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:16546 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,546 | train | mutant | 7,320 | 341 | 7,990 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23Q|S24D | G23Q|S24D | 2 | 2 | 0 | 0 | 23 | G | Q | 4 | CONSERVATION | 1C9O | 231 | null | 23|24 | A|B | E|S|L | false | false | 68.854291 | 17.0275 | 16,704 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | NaCl | 2 M | 1C9O_A:G23Q 1C9O_A:S24D | null | null | 2.1 | 0.1 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":61466,"numValue":2.1,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":61467,"numValue":0.1,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":61468,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||
fireprotdb:16547 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,547 | train | mutant | 7,320 | 341 | 7,990 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23Q|S24D | G23Q|S24D | 2 | 2 | 0 | 0 | 23 | G | Q | 4 | CONSERVATION | 1C9O | 231 | null | 23|24 | A|B | E|S|L | false | false | 68.854291 | 17.0275 | 16,866 | ProTherm | 7 | CD | GdnHCl | sodium cacodylate-HCl | 100 mM | 25 | 1C9O_A:G23Q 1C9O_A:S24D | null | null | 1.27 | -0.07 | null | null | null | 2.75 | 1.67 | null | null | null | null | null | null | null | yes | DG|DDG|M|CM|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","typ... | [{"datasets":[],"id":61971,"numValue":1.27,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":61972,"numValue":-0.07,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":61973,"numValue":1.67,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":61974,"numValue":2.75,"references":[]... | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:16548 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,548 | train | mutant | 4,901,416 | 341 | 4,908,002 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23A | G23A | 1 | 1 | 0 | 0 | 23 | G | A | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 5,083,240 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.02987 | 0.045796 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159162,"numValue":0.0298697391434749,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159163,"numValue":0.0457956924691504,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16549 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,549 | train | mutant | 4,901,417 | 341 | 4,908,003 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23C | G23C | 1 | 1 | 0 | 0 | 23 | G | C | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 5,083,241 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.028594 | 0.05852 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159164,"numValue":0.0285935028192855,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159165,"numValue":0.0585203554647744,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16550 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,550 | train | mutant | 4,901,418 | 341 | 4,908,004 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23D | G23D | 1 | 1 | 0 | 0 | 23 | G | D | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 5,083,242 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.026106 | 0.072744 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159166,"numValue":0.0261062349993606,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159167,"numValue":0.07274369216529,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16552 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,552 | train | mutant | 4,901,420 | 341 | 4,908,006 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23F | G23F | 1 | 1 | 0 | 0 | 23 | G | F | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 5,083,244 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.034342 | 0.048669 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159170,"numValue":-0.0343416048330637,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159171,"numValue":0.0486685164397222,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16553 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,553 | train | mutant | 4,902,262 | 341 | 4,908,848 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23H | G23H | 1 | 1 | 0 | 0 | 23 | G | H | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 5,084,104 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.052926 | 0.079894 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160890,"numValue":-0.0529255737135377,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160891,"numValue":0.0798936979908227,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16554 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,554 | train | mutant | 4,902,263 | 341 | 4,908,849 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23I | G23I | 1 | 1 | 0 | 0 | 23 | G | I | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 5,084,105 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.040799 | 0.055365 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160892,"numValue":-0.0407992539346518,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160893,"numValue":0.0553648507797207,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16555 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,555 | train | mutant | 4,902,264 | 341 | 4,908,850 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23K | G23K | 1 | 1 | 0 | 0 | 23 | G | K | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 5,084,106 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.051961 | 0.057398 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160894,"numValue":0.0519605422524227,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160895,"numValue":0.0573977298609986,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16556 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,556 | train | mutant | 4,902,265 | 341 | 4,908,851 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23L | G23L | 1 | 1 | 0 | 0 | 23 | G | L | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 5,084,107 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.003223 | 0.027122 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160896,"numValue":-0.00322348961028419,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160897,"numValue":0.0271218713350672,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16557 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,557 | train | mutant | 4,902,266 | 341 | 4,908,852 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23M | G23M | 1 | 1 | 0 | 0 | 23 | G | M | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 5,084,108 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.000381 | 0.047713 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160898,"numValue":-0.000380559089702623,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160899,"numValue":0.0477132479197403,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16558 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,558 | train | mutant | 4,902,267 | 341 | 4,908,853 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23N | G23N | 1 | 1 | 0 | 0 | 23 | G | N | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 5,084,109 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.065962 | 0.080824 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160900,"numValue":-0.0659617972349369,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160901,"numValue":0.0808235781216893,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16559 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,559 | train | mutant | 4,902,268 | 341 | 4,908,854 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23P | G23P | 1 | 1 | 0 | 0 | 23 | G | P | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 5,084,110 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.010909 | 0.044977 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160902,"numValue":-0.0109087678003051,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160903,"numValue":0.0449774192937498,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16560 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,560 | train | mutant | 4,902,269 | 341 | 4,908,855 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23R | G23R | 1 | 1 | 0 | 0 | 23 | G | R | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 5,084,112 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.028225 | 0.036983 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160906,"numValue":0.0282247991529383,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160907,"numValue":0.0369833725301539,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16561 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,561 | train | mutant | 4,902,270 | 341 | 4,908,856 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23S | G23S | 1 | 1 | 0 | 0 | 23 | G | S | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 5,084,113 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.011382 | 0.034048 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160908,"numValue":0.0113817991921782,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160909,"numValue":0.0340477088880878,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16562 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,562 | train | mutant | 4,902,271 | 341 | 4,908,857 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23T | G23T | 1 | 1 | 0 | 0 | 23 | G | T | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 5,084,114 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.002645 | 0.052209 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160910,"numValue":0.0026449449505493,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160911,"numValue":0.0522085932752841,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16563 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,563 | train | mutant | 4,902,272 | 341 | 4,908,858 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23V | G23V | 1 | 1 | 0 | 0 | 23 | G | V | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 5,084,115 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.020612 | 0.038451 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160912,"numValue":-0.0206118390453843,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160913,"numValue":0.0384511035800884,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16564 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,564 | train | mutant | 4,902,273 | 341 | 4,908,859 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23W | G23W | 1 | 1 | 0 | 0 | 23 | G | W | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 5,084,116 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.057401 | 0.039913 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160914,"numValue":-0.057400996030133,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160915,"numValue":0.0399130847496957,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16565 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,565 | train | mutant | 4,902,274 | 341 | 4,908,860 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G23Y | G23Y | 1 | 1 | 0 | 0 | 23 | G | Y | 4 | CONSERVATION | 1C9O | 231 | null | 23 | A|B | E|S | false | false | 43.757744 | 19.155 | 5,084,117 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.061204 | 0.04765 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160916,"numValue":-0.0612042158424873,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160917,"numValue":0.0476500822241037,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20765,"numValue":4.0,"position":23,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16566 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,566 | train | mutant | 316 | 341 | 351 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24D | S24D | 1 | 1 | 0 | 0 | 24 | S | D | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 561 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | null | 1C9O_A:S24D | 77.8 | 0.9 | null | null | null | null | 61.66 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | AUTOMUTE_S1749.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:S24D... | [{"datasets":[],"id":2228,"numValue":77.8,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","Saraboji_S1791.csv"],"id":2229,"numValue":0.9,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":2230,"numValue":61.66,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"i... | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16567 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,567 | train | mutant | 316 | 341 | 351 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24D | S24D | 1 | 1 | 0 | 0 | 24 | S | D | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 4,179 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | null | 1C9O_A:S24D | 77.8 | 0.9 | null | null | null | null | 61.66 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | AUTOMUTE_S1749.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:S24D"... | [{"datasets":[],"id":15498,"numValue":77.8,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","Saraboji_S1791.csv"],"id":15499,"numValue":0.9,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":15500,"numValue":61.66,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[]... | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16568 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,568 | train | mutant | 316 | 341 | 351 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24D | S24D | 1 | 1 | 0 | 0 | 24 | S | D | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 6,617 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | 1C9O_A:S24D | null | null | 1.29 | -0.22 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":23616,"numValue":1.29,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","potapov_with_uniprot_mapping.csv"],"id":23617,"numValue":-0.22,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23618,"numValue":null,"references":[],"strValue":"yes","type":"... | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16569 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,569 | train | mutant | 316 | 341 | 351 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24D | S24D | 1 | 1 | 0 | 0 | 24 | S | D | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 6,631 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | NaCl | 2 M | 1C9O_A:S24D | null | null | 2.39 | -0.19 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":23658,"numValue":2.39,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":23659,"numValue":-0.19,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23660,"numValue":null,"referenc... | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:16570 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,570 | train | mutant | 316 | 341 | 351 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24D | S24D | 1 | 1 | 0 | 0 | 24 | S | D | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 6,651 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | 70 | 1C9O_A:S24D | null | null | 1.29 | -0.22 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","typ... | [{"datasets":[],"id":23714,"numValue":1.29,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","potapov_with_uniprot_mapping.csv"],"id":23715,"numValue":-0.22,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23716,"numValue":null,"references":[],"strValue":"yes","type":"... | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16571 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,571 | train | mutant | 316 | 341 | 351 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24D | S24D | 1 | 1 | 0 | 0 | 24 | S | D | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 6,661 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | 70 | NaCl | 2 M | 1C9O_A:S24D | null | null | 2.39 | -0.19 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","typ... | [{"datasets":[],"id":23744,"numValue":2.39,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":23745,"numValue":-0.19,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23746,"numValue":null,"referenc... | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:16572 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,572 | train | mutant | 316 | 341 | 351 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24D | S24D | 1 | 1 | 0 | 0 | 24 | S | D | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 8,803 | ProTherm | 7 | CD | GdnHCl | sodium cacodylate-HCl | 100 mM | 25 | 1C9O_A:S24D | null | null | 1.29 | -0.1 | null | null | null | 2.79 | 1.65 | null | null | null | null | null | null | null | yes | DG|DDG|M|CM|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","typ... | [{"datasets":[],"id":29769,"numValue":1.29,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":29770,"numValue":-0.1,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":29771,"numValue":1.65,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":29772,"numValue":2.79,"references":[],... | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:16573 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,573 | train | mutant | 316 | 341 | 351 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24D | S24D | 1 | 1 | 0 | 0 | 24 | S | D | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 5,083,248 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.001833 | 0.070507 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159178,"numValue":-0.00183344122188473,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159179,"numValue":0.0705069887179775,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16575 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,575 | train | mutant | 7,945 | 341 | 8,661 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | E50W|S24C | E50W|S24C | 2 | 2 | 0 | 0 | 50 | E | W | 1 | CONSERVATION | 1C9O | 231 | null | 24|50 | A|B | E|L | true | true | 72.608339 | 17.433889 | 16,945 | ProTherm | 7 | Fluorescence | GdnHCl | sodium cacodylate | 100 mM | 25 | 1C9O_A:S24C 1C9O_A:E50W | null | null | 3.44 | 0.8 | null | null | null | 2.09 | 1.64 | null | null | null | null | null | null | null | yes | DG|DDG|M|CM|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 623 | ARTICLE | Rapid collapse precedes the fast two-state folding of the cold shock protein. | 2,004 | 10.1016/j.jmb.2003.11.050 | 14729346 | J Mol Biol;335;1309-23 | 2 | Schmid Franz X|Magg Christine | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"100 mM... | [{"datasets":[],"id":62285,"numValue":3.44,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":62286,"numValue":0.8,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":62287,"numValue":1.64,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":62288,"numValue":2.09,"references":[],"... | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20792,"numValue":5.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:16576 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,576 | train | mutant | 7,945 | 341 | 8,661 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | E50W|S24C | E50W|S24C | 2 | 2 | 0 | 0 | 50 | E | W | 1 | CONSERVATION | 1C9O | 231 | null | 24|50 | A|B | E|L | true | true | 72.608339 | 17.433889 | 16,946 | ProTherm | 7 | Fluorescence | GdnHCl | sodium cacodylate | 100 mM | 25 | 1C9O_A:S24C 1C9O_A:E50W | null | null | 2.92 | 0.3 | null | null | null | 2.05 | 1.43 | null | null | null | null | null | null | null | yes | DG|DDG|M|CM|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 623 | ARTICLE | Rapid collapse precedes the fast two-state folding of the cold shock protein. | 2,004 | 10.1016/j.jmb.2003.11.050 | 14729346 | J Mol Biol;335;1309-23 | 2 | Schmid Franz X|Magg Christine | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"Fluorescence","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate","type":"BUFFER"},{"numValue":null,"strValue":"100 mM... | [{"datasets":[],"id":62290,"numValue":2.92,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":62291,"numValue":0.3,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":62292,"numValue":1.43,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":62293,"numValue":2.05,"references":[],"... | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":20792,"numValue":5.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:16577 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,577 | train | mutant | 4,901,421 | 341 | 4,908,007 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delS24 | delS24 | 1 | 0 | 1 | 0 | 24 | S | - | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 5,083,245 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.814224 | 0.077645 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159172,"numValue":-0.814224074107848,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159173,"numValue":0.0776447834574544,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16578 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,578 | train | mutant | 4,901,422 | 341 | 4,908,008 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24A | S24A | 1 | 1 | 0 | 0 | 24 | S | A | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 5,083,246 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.011004 | 0.054979 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159174,"numValue":-0.0110036111871468,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159175,"numValue":0.0549790515928952,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16579 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,579 | train | mutant | 4,901,423 | 341 | 4,908,009 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24C | S24C | 1 | 1 | 0 | 0 | 24 | S | C | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 5,083,247 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.029032 | 0.040552 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159176,"numValue":-0.029031560712261,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159177,"numValue":0.0405519498034618,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16580 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,580 | train | mutant | 4,901,424 | 341 | 4,908,010 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24E | S24E | 1 | 1 | 0 | 0 | 24 | S | E | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 5,083,249 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.011686 | 0.053396 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159180,"numValue":0.0116864835724073,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159181,"numValue":0.0533955464061853,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16581 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,581 | train | mutant | 4,901,425 | 341 | 4,908,011 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24F | S24F | 1 | 1 | 0 | 0 | 24 | S | F | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 5,083,250 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.025327 | 0.057811 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159182,"numValue":-0.0253273336849228,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159183,"numValue":0.0578112233167819,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16583 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,583 | train | mutant | 4,901,427 | 341 | 4,908,013 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24H | S24H | 1 | 1 | 0 | 0 | 24 | S | H | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 5,083,252 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.007018 | 0.071517 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159186,"numValue":0.00701841062628976,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159187,"numValue":0.071516596570908,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16584 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,584 | train | mutant | 4,901,428 | 341 | 4,908,014 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24I | S24I | 1 | 1 | 0 | 0 | 24 | S | I | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 5,083,253 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.032976 | 0.080583 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159188,"numValue":-0.0329758600625425,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159189,"numValue":0.0805829723046952,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16585 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,585 | train | mutant | 4,901,429 | 341 | 4,908,015 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24K | S24K | 1 | 1 | 0 | 0 | 24 | S | K | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 5,083,254 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.015164 | 0.04907 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159190,"numValue":0.0151636792424931,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159191,"numValue":0.0490695320624241,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16586 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,586 | train | mutant | 4,901,430 | 341 | 4,908,016 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24L | S24L | 1 | 1 | 0 | 0 | 24 | S | L | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 5,083,255 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.002126 | 0.032841 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159192,"numValue":-0.0021256774075909,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159193,"numValue":0.0328414254894059,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16587 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,587 | train | mutant | 4,901,431 | 341 | 4,908,017 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24M | S24M | 1 | 1 | 0 | 0 | 24 | S | M | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 5,083,256 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.019048 | 0.054806 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159194,"numValue":-0.0190481087048308,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159195,"numValue":0.0548057193757302,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16588 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,588 | train | mutant | 4,901,432 | 341 | 4,908,018 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24N | S24N | 1 | 1 | 0 | 0 | 24 | S | N | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 5,083,257 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.004285 | 0.080715 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159196,"numValue":0.004285142771744,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159197,"numValue":0.080714863889522,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16589 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,589 | train | mutant | 4,901,433 | 341 | 4,908,019 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24P | S24P | 1 | 1 | 0 | 0 | 24 | S | P | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 5,083,258 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.011586 | 0.05683 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159198,"numValue":0.011585712473888,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159199,"numValue":0.0568296831786449,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16590 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,590 | train | mutant | 4,901,434 | 341 | 4,908,020 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24Q | S24Q | 1 | 1 | 0 | 0 | 24 | S | Q | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 5,083,259 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.003726 | 0.054542 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159200,"numValue":-0.00372615956054546,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159201,"numValue":0.0545424044952991,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16591 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,591 | train | mutant | 4,901,435 | 341 | 4,908,021 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24R | S24R | 1 | 1 | 0 | 0 | 24 | S | R | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 5,083,260 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.009605 | 0.029213 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159202,"numValue":0.00960467123123085,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159203,"numValue":0.0292132450751797,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16592 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,592 | train | mutant | 4,902,258 | 341 | 4,908,844 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24T | S24T | 1 | 1 | 0 | 0 | 24 | S | T | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 5,084,100 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.002569 | 0.046549 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160882,"numValue":0.00256907024107602,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160883,"numValue":0.0465485177799185,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16593 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,593 | train | mutant | 4,902,259 | 341 | 4,908,845 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24V | S24V | 1 | 1 | 0 | 0 | 24 | S | V | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 5,084,101 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.016082 | 0.03871 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160884,"numValue":-0.0160824745525229,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160885,"numValue":0.0387100734478599,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16594 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,594 | train | mutant | 4,902,260 | 341 | 4,908,846 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24W | S24W | 1 | 1 | 0 | 0 | 24 | S | W | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 5,084,102 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.030584 | 0.039473 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160886,"numValue":-0.030584028400627,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160887,"numValue":0.0394731892661003,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16595 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,595 | train | mutant | 4,902,261 | 341 | 4,908,847 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | S24Y | S24Y | 1 | 1 | 0 | 0 | 24 | S | Y | 1 | CONSERVATION | 1C9O | 231 | null | 24 | A|B | E|L | false | false | 93.950838 | 14.9 | 5,084,103 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.015848 | 0.083945 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160888,"numValue":-0.0158483299412571,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160889,"numValue":0.0839447554284179,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20766,"numValue":1.0,"position":24,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16596 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,596 | train | mutant | 4,901,436 | 341 | 4,908,022 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delD25 | delD25 | 1 | 0 | 1 | 0 | 25 | D | - | 8 | CONSERVATION | 1C9O | 231 | null | 25 | A|B | E|L | true | false | 57.243361 | 13.296875 | 5,083,261 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.233215 | 0.129485 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159204,"numValue":-1.23321459331542,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159205,"numValue":0.129484815331471,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20767,"numValue":8.0,"position":25,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16597 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,597 | train | mutant | 4,901,437 | 341 | 4,908,023 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | D25A | D25A | 1 | 1 | 0 | 0 | 25 | D | A | 8 | CONSERVATION | 1C9O | 231 | null | 25 | A|B | E|L | true | false | 57.243361 | 13.296875 | 5,083,262 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.112983 | 0.040473 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159206,"numValue":-0.112983370117575,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159207,"numValue":0.0404726310935037,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20767,"numValue":8.0,"position":25,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16599 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,599 | train | mutant | 4,902,241 | 341 | 4,908,827 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | D25E | D25E | 1 | 1 | 0 | 0 | 25 | D | E | 8 | CONSERVATION | 1C9O | 231 | null | 25 | A|B | E|L | true | false | 57.243361 | 13.296875 | 5,084,083 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.081689 | 0.04322 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160848,"numValue":-0.0816892018579708,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160849,"numValue":0.0432198705644736,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20767,"numValue":8.0,"position":25,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16600 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,600 | train | mutant | 4,902,242 | 341 | 4,908,828 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | D25F | D25F | 1 | 1 | 0 | 0 | 25 | D | F | 8 | CONSERVATION | 1C9O | 231 | null | 25 | A|B | E|L | true | false | 57.243361 | 13.296875 | 5,084,084 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.250617 | 0.05449 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160850,"numValue":-0.25061712924649,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160851,"numValue":0.0544904006807514,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20767,"numValue":8.0,"position":25,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16601 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,601 | train | mutant | 4,902,243 | 341 | 4,908,829 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | D25G | D25G | 1 | 1 | 0 | 0 | 25 | D | G | 8 | CONSERVATION | 1C9O | 231 | null | 25 | A|B | E|L | true | false | 57.243361 | 13.296875 | 5,084,085 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.256762 | 0.047443 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160852,"numValue":-0.256762387942668,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160853,"numValue":0.0474431220985917,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20767,"numValue":8.0,"position":25,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16602 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,602 | train | mutant | 4,902,244 | 341 | 4,908,830 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | D25H | D25H | 1 | 1 | 0 | 0 | 25 | D | H | 8 | CONSERVATION | 1C9O | 231 | null | 25 | A|B | E|L | true | false | 57.243361 | 13.296875 | 5,084,086 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.102021 | 0.064071 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160854,"numValue":-0.102021252912172,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160855,"numValue":0.0640713907038303,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20767,"numValue":8.0,"position":25,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16603 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,603 | train | mutant | 4,902,245 | 341 | 4,908,831 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | D25I | D25I | 1 | 1 | 0 | 0 | 25 | D | I | 8 | CONSERVATION | 1C9O | 231 | null | 25 | A|B | E|L | true | false | 57.243361 | 13.296875 | 5,084,087 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.213963 | 0.063432 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160856,"numValue":-0.213963124087991,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160857,"numValue":0.0634316720595827,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20767,"numValue":8.0,"position":25,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16604 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,604 | train | mutant | 4,902,246 | 341 | 4,908,832 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | D25K | D25K | 1 | 1 | 0 | 0 | 25 | D | K | 8 | CONSERVATION | 1C9O | 231 | null | 25 | A|B | E|L | true | false | 57.243361 | 13.296875 | 5,084,088 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.092927 | 0.045985 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160858,"numValue":-0.0929269576563831,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160859,"numValue":0.0459851006403851,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20767,"numValue":8.0,"position":25,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16606 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,606 | train | mutant | 4,902,248 | 341 | 4,908,834 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | D25M | D25M | 1 | 1 | 0 | 0 | 25 | D | M | 8 | CONSERVATION | 1C9O | 231 | null | 25 | A|B | E|L | true | false | 57.243361 | 13.296875 | 5,084,090 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.152517 | 0.04268 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160862,"numValue":-0.152517057609057,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160863,"numValue":0.0426804547295228,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20767,"numValue":8.0,"position":25,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16607 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,607 | train | mutant | 4,902,249 | 341 | 4,908,835 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | D25N | D25N | 1 | 1 | 0 | 0 | 25 | D | N | 8 | CONSERVATION | 1C9O | 231 | null | 25 | A|B | E|L | true | false | 57.243361 | 13.296875 | 5,084,091 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.046736 | 0.079678 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160864,"numValue":-0.0467364499509455,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160865,"numValue":0.0796779292857577,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20767,"numValue":8.0,"position":25,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16608 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,608 | train | mutant | 4,902,250 | 341 | 4,908,836 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | D25P | D25P | 1 | 1 | 0 | 0 | 25 | D | P | 8 | CONSERVATION | 1C9O | 231 | null | 25 | A|B | E|L | true | false | 57.243361 | 13.296875 | 5,084,092 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.093063 | 0.035969 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160866,"numValue":-0.0930632950249681,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160867,"numValue":0.03596919441152,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20767,"numValue":8.0,"position":25,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16609 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,609 | train | mutant | 4,902,251 | 341 | 4,908,837 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | D25Q | D25Q | 1 | 1 | 0 | 0 | 25 | D | Q | 8 | CONSERVATION | 1C9O | 231 | null | 25 | A|B | E|L | true | false | 57.243361 | 13.296875 | 5,084,093 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.073188 | 0.053925 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160868,"numValue":-0.073187677769943,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160869,"numValue":0.0539246717336637,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20767,"numValue":8.0,"position":25,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16611 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,611 | train | mutant | 4,902,253 | 341 | 4,908,839 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | D25S | D25S | 1 | 1 | 0 | 0 | 25 | D | S | 8 | CONSERVATION | 1C9O | 231 | null | 25 | A|B | E|L | true | false | 57.243361 | 13.296875 | 5,084,095 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.052815 | 0.031508 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160872,"numValue":-0.0528153182763341,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160873,"numValue":0.0315083068439582,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20767,"numValue":8.0,"position":25,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16612 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,612 | train | mutant | 4,902,254 | 341 | 4,908,840 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | D25T | D25T | 1 | 1 | 0 | 0 | 25 | D | T | 8 | CONSERVATION | 1C9O | 231 | null | 25 | A|B | E|L | true | false | 57.243361 | 13.296875 | 5,084,096 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.072724 | 0.041009 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160874,"numValue":-0.072724130716754,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160875,"numValue":0.0410091482774441,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20767,"numValue":8.0,"position":25,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16613 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,613 | train | mutant | 4,902,255 | 341 | 4,908,841 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | D25V | D25V | 1 | 1 | 0 | 0 | 25 | D | V | 8 | CONSERVATION | 1C9O | 231 | null | 25 | A|B | E|L | true | false | 57.243361 | 13.296875 | 5,084,097 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.141305 | 0.035451 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160876,"numValue":-0.141305383742026,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160877,"numValue":0.0354510412783568,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20767,"numValue":8.0,"position":25,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16614 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,614 | train | mutant | 4,902,256 | 341 | 4,908,842 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | D25W | D25W | 1 | 1 | 0 | 0 | 25 | D | W | 8 | CONSERVATION | 1C9O | 231 | null | 25 | A|B | E|L | true | false | 57.243361 | 13.296875 | 5,084,098 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.260092 | 0.035739 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160878,"numValue":-0.260091983591981,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160879,"numValue":0.035738624210396,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20767,"numValue":8.0,"position":25,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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