row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:16615 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,615 | train | mutant | 4,902,257 | 341 | 4,908,843 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | D25Y | D25Y | 1 | 1 | 0 | 0 | 25 | D | Y | 8 | CONSERVATION | 1C9O | 231 | null | 25 | A|B | E|L | true | false | 57.243361 | 13.296875 | 5,084,099 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.230958 | 0.059816 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160880,"numValue":-0.230957873467698,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160881,"numValue":0.0598164199845253,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20767,"numValue":8.0,"position":25,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16616 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,616 | train | mutant | 4,901,439 | 341 | 4,908,025 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delV26 | delV26 | 1 | 0 | 1 | 0 | 26 | V | - | 7 | CONSERVATION | 1C9O | 231 | null | 26 | A|B | E | false | false | 7.927886 | 10.865714 | 5,083,264 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.001411 | 0.083443 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159210,"numValue":-1.00141083539132,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159211,"numValue":0.0834427375264412,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20768,"numValue":7.0,"position":26,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16618 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,618 | train | mutant | 4,901,441 | 341 | 4,908,027 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V26C | V26C | 1 | 1 | 0 | 0 | 26 | V | C | 7 | CONSERVATION | 1C9O | 231 | null | 26 | A|B | E | false | false | 7.927886 | 10.865714 | 5,083,266 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.052594 | 0.047606 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159214,"numValue":-0.0525942146307593,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159215,"numValue":0.0476059029889705,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20768,"numValue":7.0,"position":26,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16619 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,619 | train | mutant | 4,901,442 | 341 | 4,908,028 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V26D | V26D | 1 | 1 | 0 | 0 | 26 | V | D | 7 | CONSERVATION | 1C9O | 231 | null | 26 | A|B | E | false | false | 7.927886 | 10.865714 | 5,083,267 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.52927 | 0.059894 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159216,"numValue":-0.529270141474753,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159217,"numValue":0.059893539513451,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20768,"numValue":7.0,"position":26,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16620 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,620 | train | mutant | 4,901,443 | 341 | 4,908,029 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V26E | V26E | 1 | 1 | 0 | 0 | 26 | V | E | 7 | CONSERVATION | 1C9O | 231 | null | 26 | A|B | E | false | false | 7.927886 | 10.865714 | 5,083,268 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.371867 | 0.042567 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159218,"numValue":-0.371866693298492,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159219,"numValue":0.0425669212677615,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20768,"numValue":7.0,"position":26,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16621 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,621 | train | mutant | 4,901,444 | 341 | 4,908,030 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V26F | V26F | 1 | 1 | 0 | 0 | 26 | V | F | 7 | CONSERVATION | 1C9O | 231 | null | 26 | A|B | E | false | false | 7.927886 | 10.865714 | 5,083,269 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.109679 | 0.054083 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159220,"numValue":-0.109679263628476,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159221,"numValue":0.0540825978281786,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20768,"numValue":7.0,"position":26,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16622 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,622 | train | mutant | 4,901,445 | 341 | 4,908,031 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V26G | V26G | 1 | 1 | 0 | 0 | 26 | V | G | 7 | CONSERVATION | 1C9O | 231 | null | 26 | A|B | E | false | false | 7.927886 | 10.865714 | 5,083,270 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.573056 | 0.036179 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159222,"numValue":-0.573056191492402,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159223,"numValue":0.0361785552602615,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20768,"numValue":7.0,"position":26,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16623 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,623 | train | mutant | 4,901,446 | 341 | 4,908,032 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V26H | V26H | 1 | 1 | 0 | 0 | 26 | V | H | 7 | CONSERVATION | 1C9O | 231 | null | 26 | A|B | E | false | false | 7.927886 | 10.865714 | 5,083,271 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.132235 | 0.074758 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159224,"numValue":-0.132234799332948,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159225,"numValue":0.0747576914848746,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20768,"numValue":7.0,"position":26,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16624 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,624 | train | mutant | 4,901,447 | 341 | 4,908,033 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V26I | V26I | 1 | 1 | 0 | 0 | 26 | V | I | 7 | CONSERVATION | 1C9O | 231 | null | 26 | A|B | E | false | false | 7.927886 | 10.865714 | 5,083,272 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.016518 | 0.044574 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159226,"numValue":-0.0165175685896592,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159227,"numValue":0.0445738251164681,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20768,"numValue":7.0,"position":26,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16625 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,625 | train | mutant | 4,901,448 | 341 | 4,908,034 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V26K | V26K | 1 | 1 | 0 | 0 | 26 | V | K | 7 | CONSERVATION | 1C9O | 231 | null | 26 | A|B | E | false | false | 7.927886 | 10.865714 | 5,083,273 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.25057 | 0.059121 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159228,"numValue":-0.250569707553069,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159229,"numValue":0.0591213839349022,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20768,"numValue":7.0,"position":26,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16627 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,627 | train | mutant | 4,901,450 | 341 | 4,908,036 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V26M | V26M | 1 | 1 | 0 | 0 | 26 | V | M | 7 | CONSERVATION | 1C9O | 231 | null | 26 | A|B | E | false | false | 7.927886 | 10.865714 | 5,083,275 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.056476 | 0.043329 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159232,"numValue":-0.056476273008426,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159233,"numValue":0.0433288515436664,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20768,"numValue":7.0,"position":26,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16629 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,629 | train | mutant | 4,901,452 | 341 | 4,908,038 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V26P | V26P | 1 | 1 | 0 | 0 | 26 | V | P | 7 | CONSERVATION | 1C9O | 231 | null | 26 | A|B | E | false | false | 7.927886 | 10.865714 | 5,083,277 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.566317 | 0.038149 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159236,"numValue":-0.566317035363245,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159237,"numValue":0.0381491933689244,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20768,"numValue":7.0,"position":26,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16630 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,630 | train | mutant | 4,901,453 | 341 | 4,908,039 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V26Q | V26Q | 1 | 1 | 0 | 0 | 26 | V | Q | 7 | CONSERVATION | 1C9O | 231 | null | 26 | A|B | E | false | false | 7.927886 | 10.865714 | 5,083,278 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.172686 | 0.040387 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159238,"numValue":-0.172685503820956,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159239,"numValue":0.0403872068405176,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20768,"numValue":7.0,"position":26,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16631 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,631 | train | mutant | 4,901,454 | 341 | 4,908,040 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V26R | V26R | 1 | 1 | 0 | 0 | 26 | V | R | 7 | CONSERVATION | 1C9O | 231 | null | 26 | A|B | E | false | false | 7.927886 | 10.865714 | 5,083,279 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.247791 | 0.03203 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159240,"numValue":-0.247790796318606,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159241,"numValue":0.0320302477848834,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20768,"numValue":7.0,"position":26,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16632 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,632 | train | mutant | 4,901,455 | 341 | 4,908,041 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V26S | V26S | 1 | 1 | 0 | 0 | 26 | V | S | 7 | CONSERVATION | 1C9O | 231 | null | 26 | A|B | E | false | false | 7.927886 | 10.865714 | 5,083,280 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.194858 | 0.029445 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159242,"numValue":-0.194858109351055,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159243,"numValue":0.0294447044330553,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20768,"numValue":7.0,"position":26,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16634 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,634 | train | mutant | 4,902,239 | 341 | 4,908,825 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V26W | V26W | 1 | 1 | 0 | 0 | 26 | V | W | 7 | CONSERVATION | 1C9O | 231 | null | 26 | A|B | E | false | false | 7.927886 | 10.865714 | 5,084,081 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.230274 | 0.035092 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160844,"numValue":-0.230273815540102,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160845,"numValue":0.0350924621435548,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20768,"numValue":7.0,"position":26,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16635 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,635 | train | mutant | 4,902,240 | 341 | 4,908,826 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V26Y | V26Y | 1 | 1 | 0 | 0 | 26 | V | Y | 7 | CONSERVATION | 1C9O | 231 | null | 26 | A|B | E | false | false | 7.927886 | 10.865714 | 5,084,082 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.074199 | 0.053745 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160846,"numValue":-0.0741989453821432,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160847,"numValue":0.0537449672264453,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20768,"numValue":7.0,"position":26,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16636 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,636 | train | mutant | 4,901,457 | 341 | 4,908,043 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delF27 | delF27 | 1 | 0 | 1 | 0 | 27 | F | - | 9 | CONSERVATION | 1C9O | 231 | null | 27 | A|B | E | true | true | 63.651537 | 10.55 | 5,083,282 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.043799 | 0.084599 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159246,"numValue":-1.0437992851159,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159247,"numValue":0.0845992933518596,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20769,"numValue":9.0,"position":27,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16637 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,637 | train | mutant | 4,901,458 | 341 | 4,908,044 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F27A | F27A | 1 | 1 | 0 | 0 | 27 | F | A | 9 | CONSERVATION | 1C9O | 231 | null | 27 | A|B | E | true | true | 63.651537 | 10.55 | 5,083,283 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.205521 | 0.036875 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159248,"numValue":-0.205520877116739,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159249,"numValue":0.0368747649967967,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20769,"numValue":9.0,"position":27,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16638 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,638 | train | mutant | 4,901,459 | 341 | 4,908,045 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F27C | F27C | 1 | 1 | 0 | 0 | 27 | F | C | 9 | CONSERVATION | 1C9O | 231 | null | 27 | A|B | E | true | true | 63.651537 | 10.55 | 5,083,284 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.242892 | 0.046814 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159250,"numValue":-0.242892135388229,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159251,"numValue":0.0468143875040827,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20769,"numValue":9.0,"position":27,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16640 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,640 | train | mutant | 4,901,461 | 341 | 4,908,047 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F27E | F27E | 1 | 1 | 0 | 0 | 27 | F | E | 9 | CONSERVATION | 1C9O | 231 | null | 27 | A|B | E | true | true | 63.651537 | 10.55 | 5,083,286 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.183202 | 0.041002 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159254,"numValue":-0.183201857108204,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159255,"numValue":0.0410024558909601,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20769,"numValue":9.0,"position":27,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16641 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,641 | train | mutant | 4,902,224 | 341 | 4,908,810 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F27G | F27G | 1 | 1 | 0 | 0 | 27 | F | G | 9 | CONSERVATION | 1C9O | 231 | null | 27 | A|B | E | true | true | 63.651537 | 10.55 | 5,084,066 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.229101 | 0.031053 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160814,"numValue":-0.229100721399103,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160815,"numValue":0.0310530763702528,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20769,"numValue":9.0,"position":27,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16642 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,642 | train | mutant | 4,902,225 | 341 | 4,908,811 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F27H | F27H | 1 | 1 | 0 | 0 | 27 | F | H | 9 | CONSERVATION | 1C9O | 231 | null | 27 | A|B | E | true | true | 63.651537 | 10.55 | 5,084,067 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.07529 | 0.076728 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160816,"numValue":-0.0752902371019911,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160817,"numValue":0.0767284185092127,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20769,"numValue":9.0,"position":27,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16643 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,643 | train | mutant | 4,902,226 | 341 | 4,908,812 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F27I | F27I | 1 | 1 | 0 | 0 | 27 | F | I | 9 | CONSERVATION | 1C9O | 231 | null | 27 | A|B | E | true | true | 63.651537 | 10.55 | 5,084,068 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.208372 | 0.055822 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160818,"numValue":-0.208371513662502,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160819,"numValue":0.055821978121163,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20769,"numValue":9.0,"position":27,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16645 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,645 | train | mutant | 4,902,228 | 341 | 4,908,814 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F27L | F27L | 1 | 1 | 0 | 0 | 27 | F | L | 9 | CONSERVATION | 1C9O | 231 | null | 27 | A|B | E | true | true | 63.651537 | 10.55 | 5,084,070 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.187087 | 0.029444 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160822,"numValue":-0.187086879341709,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160823,"numValue":0.0294441709390043,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20769,"numValue":9.0,"position":27,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16646 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,646 | train | mutant | 4,902,229 | 341 | 4,908,815 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F27M | F27M | 1 | 1 | 0 | 0 | 27 | F | M | 9 | CONSERVATION | 1C9O | 231 | null | 27 | A|B | E | true | true | 63.651537 | 10.55 | 5,084,071 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.169464 | 0.049243 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160824,"numValue":-0.169464385295343,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160825,"numValue":0.0492429531952643,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20769,"numValue":9.0,"position":27,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16647 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,647 | train | mutant | 4,902,230 | 341 | 4,908,816 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F27N | F27N | 1 | 1 | 0 | 0 | 27 | F | N | 9 | CONSERVATION | 1C9O | 231 | null | 27 | A|B | E | true | true | 63.651537 | 10.55 | 5,084,072 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.335389 | 0.104289 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160826,"numValue":-0.335389333947986,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160827,"numValue":0.104289017568675,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20769,"numValue":9.0,"position":27,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16648 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,648 | train | mutant | 4,902,231 | 341 | 4,908,817 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F27P | F27P | 1 | 1 | 0 | 0 | 27 | F | P | 9 | CONSERVATION | 1C9O | 231 | null | 27 | A|B | E | true | true | 63.651537 | 10.55 | 5,084,073 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.161442 | 0.041842 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160828,"numValue":-0.161441820310866,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160829,"numValue":0.0418416420331593,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20769,"numValue":9.0,"position":27,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16649 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,649 | train | mutant | 4,902,232 | 341 | 4,908,818 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F27Q | F27Q | 1 | 1 | 0 | 0 | 27 | F | Q | 9 | CONSERVATION | 1C9O | 231 | null | 27 | A|B | E | true | true | 63.651537 | 10.55 | 5,084,074 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.208379 | 0.040154 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160830,"numValue":-0.208378626916515,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160831,"numValue":0.0401537913377884,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20769,"numValue":9.0,"position":27,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16650 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,650 | train | mutant | 4,902,233 | 341 | 4,908,819 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F27R | F27R | 1 | 1 | 0 | 0 | 27 | F | R | 9 | CONSERVATION | 1C9O | 231 | null | 27 | A|B | E | true | true | 63.651537 | 10.55 | 5,084,075 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.176106 | 0.028393 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160832,"numValue":-0.176106386230105,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160833,"numValue":0.0283934188393196,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20769,"numValue":9.0,"position":27,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16651 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,651 | train | mutant | 4,902,234 | 341 | 4,908,820 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F27S | F27S | 1 | 1 | 0 | 0 | 27 | F | S | 9 | CONSERVATION | 1C9O | 231 | null | 27 | A|B | E | true | true | 63.651537 | 10.55 | 5,084,076 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.211576 | 0.030011 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160834,"numValue":-0.211576034595418,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160835,"numValue":0.0300109965127524,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20769,"numValue":9.0,"position":27,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16654 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,654 | train | mutant | 4,902,237 | 341 | 4,908,823 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F27W | F27W | 1 | 1 | 0 | 0 | 27 | F | W | 9 | CONSERVATION | 1C9O | 231 | null | 27 | A|B | E | true | true | 63.651537 | 10.55 | 5,084,079 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.102146 | 0.034571 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160840,"numValue":-0.102146327628569,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160841,"numValue":0.0345712621665893,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20769,"numValue":9.0,"position":27,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16655 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,655 | train | mutant | 4,902,238 | 341 | 4,908,824 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F27Y | F27Y | 1 | 1 | 0 | 0 | 27 | F | Y | 9 | CONSERVATION | 1C9O | 231 | null | 27 | A|B | E | true | true | 63.651537 | 10.55 | 5,084,080 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.002866 | 0.054273 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160842,"numValue":0.00286604859612425,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160843,"numValue":0.0542725217103292,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20769,"numValue":9.0,"position":27,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16656 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,656 | train | mutant | 4,901,462 | 341 | 4,908,048 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delV28 | delV28 | 1 | 0 | 1 | 0 | 28 | V | - | 8 | CONSERVATION | 1C9O | 231 | null | 28 | A|B | E | true | true | 0.067185 | 9.173571 | 5,083,287 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.181304 | 0.122789 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159256,"numValue":-1.18130402167244,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159257,"numValue":0.122788516557743,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20770,"numValue":8.0,"position":28,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16657 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,657 | train | mutant | 4,901,463 | 341 | 4,908,049 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V28A | V28A | 1 | 1 | 0 | 0 | 28 | V | A | 8 | CONSERVATION | 1C9O | 231 | null | 28 | A|B | E | true | true | 0.067185 | 9.173571 | 5,083,288 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.100191 | 0.044973 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159258,"numValue":-0.100190775546126,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159259,"numValue":0.0449731394859186,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20770,"numValue":8.0,"position":28,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16658 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,658 | train | mutant | 4,901,464 | 341 | 4,908,050 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V28C | V28C | 1 | 1 | 0 | 0 | 28 | V | C | 8 | CONSERVATION | 1C9O | 231 | null | 28 | A|B | E | true | true | 0.067185 | 9.173571 | 5,083,289 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.016779 | 0.048458 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159260,"numValue":0.0167789806746418,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159261,"numValue":0.0484579581932218,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20770,"numValue":8.0,"position":28,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16659 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,659 | train | mutant | 4,901,465 | 341 | 4,908,051 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V28D | V28D | 1 | 1 | 0 | 0 | 28 | V | D | 8 | CONSERVATION | 1C9O | 231 | null | 28 | A|B | E | true | true | 0.067185 | 9.173571 | 5,083,290 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.911551 | 0.137822 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159262,"numValue":-0.91155081647982,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159263,"numValue":0.137821608311978,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20770,"numValue":8.0,"position":28,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16660 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,660 | train | mutant | 4,901,466 | 341 | 4,908,052 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V28E | V28E | 1 | 1 | 0 | 0 | 28 | V | E | 8 | CONSERVATION | 1C9O | 231 | null | 28 | A|B | E | true | true | 0.067185 | 9.173571 | 5,083,291 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.095662 | 0.146864 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159264,"numValue":-1.09566202012564,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159265,"numValue":0.146864332476172,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20770,"numValue":8.0,"position":28,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16661 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,661 | train | mutant | 4,901,467 | 341 | 4,908,053 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V28F | V28F | 1 | 1 | 0 | 0 | 28 | V | F | 8 | CONSERVATION | 1C9O | 231 | null | 28 | A|B | E | true | true | 0.067185 | 9.173571 | 5,083,292 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.061512 | 0.058075 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159266,"numValue":-0.0615118640785552,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159267,"numValue":0.0580754095708296,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20770,"numValue":8.0,"position":28,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16662 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,662 | train | mutant | 4,901,468 | 341 | 4,908,054 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V28G | V28G | 1 | 1 | 0 | 0 | 28 | V | G | 8 | CONSERVATION | 1C9O | 231 | null | 28 | A|B | E | true | true | 0.067185 | 9.173571 | 5,083,293 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.637903 | 0.040709 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159268,"numValue":-0.637902986160781,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159269,"numValue":0.0407092416328271,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20770,"numValue":8.0,"position":28,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16663 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,663 | train | mutant | 4,901,469 | 341 | 4,908,055 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V28H | V28H | 1 | 1 | 0 | 0 | 28 | V | H | 8 | CONSERVATION | 1C9O | 231 | null | 28 | A|B | E | true | true | 0.067185 | 9.173571 | 5,083,294 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.040708 | 0.209867 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159270,"numValue":-1.04070783528323,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159271,"numValue":0.209867075318763,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20770,"numValue":8.0,"position":28,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16664 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,664 | train | mutant | 4,901,470 | 341 | 4,908,056 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V28I | V28I | 1 | 1 | 0 | 0 | 28 | V | I | 8 | CONSERVATION | 1C9O | 231 | null | 28 | A|B | E | true | true | 0.067185 | 9.173571 | 5,083,295 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.047646 | 0.049603 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159272,"numValue":-0.0476457609222908,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159273,"numValue":0.0496032217278944,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20770,"numValue":8.0,"position":28,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16666 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,666 | train | mutant | 4,901,472 | 341 | 4,908,058 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V28L | V28L | 1 | 1 | 0 | 0 | 28 | V | L | 8 | CONSERVATION | 1C9O | 231 | null | 28 | A|B | E | true | true | 0.067185 | 9.173571 | 5,083,297 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.107037 | 0.029071 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159276,"numValue":-0.107036689762597,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159277,"numValue":0.0290709207178003,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20770,"numValue":8.0,"position":28,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16667 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,667 | train | mutant | 4,901,473 | 341 | 4,908,059 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V28M | V28M | 1 | 1 | 0 | 0 | 28 | V | M | 8 | CONSERVATION | 1C9O | 231 | null | 28 | A|B | E | true | true | 0.067185 | 9.173571 | 5,083,298 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.152771 | 0.05482 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159278,"numValue":-0.152771356440027,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159279,"numValue":0.0548202719078987,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20770,"numValue":8.0,"position":28,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16668 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,668 | train | mutant | 4,901,474 | 341 | 4,908,060 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V28N | V28N | 1 | 1 | 0 | 0 | 28 | V | N | 8 | CONSERVATION | 1C9O | 231 | null | 28 | A|B | E | true | true | 0.067185 | 9.173571 | 5,083,299 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.998611 | 0.336905 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159280,"numValue":-0.998610821503289,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159281,"numValue":0.336904516329899,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20770,"numValue":8.0,"position":28,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16669 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,669 | train | mutant | 4,901,475 | 341 | 4,908,061 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V28P | V28P | 1 | 1 | 0 | 0 | 28 | V | P | 8 | CONSERVATION | 1C9O | 231 | null | 28 | A|B | E | true | true | 0.067185 | 9.173571 | 5,083,300 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.69337 | 0.087594 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159282,"numValue":-0.693370362641677,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159283,"numValue":0.0875942103998551,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20770,"numValue":8.0,"position":28,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16670 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,670 | train | mutant | 4,901,476 | 341 | 4,908,062 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V28Q | V28Q | 1 | 1 | 0 | 0 | 28 | V | Q | 8 | CONSERVATION | 1C9O | 231 | null | 28 | A|B | E | true | true | 0.067185 | 9.173571 | 5,083,301 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.900622 | 0.084331 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159284,"numValue":-0.900621538797111,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159285,"numValue":0.0843307680128639,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20770,"numValue":8.0,"position":28,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16671 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,671 | train | mutant | 4,901,477 | 341 | 4,908,063 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V28R | V28R | 1 | 1 | 0 | 0 | 28 | V | R | 8 | CONSERVATION | 1C9O | 231 | null | 28 | A|B | E | true | true | 0.067185 | 9.173571 | 5,083,302 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.99289 | 0.049646 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159286,"numValue":-0.992890164794578,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159287,"numValue":0.0496455455892725,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20770,"numValue":8.0,"position":28,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16672 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,672 | train | mutant | 4,901,478 | 341 | 4,908,064 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V28S | V28S | 1 | 1 | 0 | 0 | 28 | V | S | 8 | CONSERVATION | 1C9O | 231 | null | 28 | A|B | E | true | true | 0.067185 | 9.173571 | 5,083,303 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.355456 | 0.029508 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159288,"numValue":-0.35545582351903,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159289,"numValue":0.0295083562010495,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20770,"numValue":8.0,"position":28,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16673 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,673 | train | mutant | 4,901,479 | 341 | 4,908,065 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V28T | V28T | 1 | 1 | 0 | 0 | 28 | V | T | 8 | CONSERVATION | 1C9O | 231 | null | 28 | A|B | E | true | true | 0.067185 | 9.173571 | 5,083,304 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.049971 | 0.046767 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159290,"numValue":-0.0499712022134172,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159291,"numValue":0.0467672503408223,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20770,"numValue":8.0,"position":28,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16674 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,674 | train | mutant | 4,902,222 | 341 | 4,908,808 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V28W | V28W | 1 | 1 | 0 | 0 | 28 | V | W | 8 | CONSERVATION | 1C9O | 231 | null | 28 | A|B | E | true | true | 0.067185 | 9.173571 | 5,084,064 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.6749 | 0.0362 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160810,"numValue":-0.674899731608479,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160811,"numValue":0.036199598636717,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20770,"numValue":8.0,"position":28,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16675 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,675 | train | mutant | 4,902,223 | 341 | 4,908,809 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V28Y | V28Y | 1 | 1 | 0 | 0 | 28 | V | Y | 8 | CONSERVATION | 1C9O | 231 | null | 28 | A|B | E | true | true | 0.067185 | 9.173571 | 5,084,065 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.269543 | 0.06117 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160812,"numValue":-0.269543127090762,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160813,"numValue":0.061170131500341,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20770,"numValue":8.0,"position":28,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16677 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,677 | train | mutant | 1,206 | 341 | 1,352 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | H29E | H29E | 1 | 1 | 0 | 0 | 29 | H | E | 9 | CONSERVATION | 1C9O | 231 | null | 29 | A|B | E | true | true | 63.398842 | 9.869 | 6,546 | ProTherm | 7 | DSC | Thermal | Na cacodylate/HCl | 0.1 M | 75 | 1C9O_A:H29E | null | null | null | 0.76 | null | 0.96 | null | null | null | null | null | null | null | null | null | null | Yes | DCP|DDG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 223 | ARTICLE | The correlation between protein stability and dipole moment: a critical test. | 2,006 | 10.1093/protein/gzl019 | 16720692 | Protein Eng Des Sel;19;355-8 | 2 | Wunderlich Michael|Schmid Franz X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":75.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Na cacodylate/HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":... | [{"datasets":[],"id":23420,"numValue":0.96,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":23421,"numValue":0.76,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23422,"numValue":null,"references":[],"strValue":"Yes","type":"REVERSIBILITY"}] | [{"id":20771,"numValue":9.0,"position":29,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:16678 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,678 | train | mutant | 1,206 | 341 | 1,352 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | H29E | H29E | 1 | 1 | 0 | 0 | 29 | H | E | 9 | CONSERVATION | 1C9O | 231 | null | 29 | A|B | E | true | true | 63.398842 | 9.869 | 6,554 | ProTherm | 7 | DSC | Thermal | Na cacodylate/HCl | 0.1 M | 75 | NaCl | 0-2 M | 1C9O_A:H29E | null | null | null | 0.29 | null | 0.96 | null | null | null | null | null | null | null | null | null | null | Yes | DCP|DDG|REVERSIBILITY | khan_protherm_data_mapped.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 223 | ARTICLE | The correlation between protein stability and dipole moment: a critical test. | 2,006 | 10.1093/protein/gzl019 | 16720692 | Protein Eng Des Sel;19;355-8 | 2 | Wunderlich Michael|Schmid Franz X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":75.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Na cacodylate/HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":... | [{"datasets":[],"id":23444,"numValue":0.96,"references":[],"strValue":null,"type":"DCP"},{"datasets":["khan_protherm_data_mapped.csv"],"id":23445,"numValue":0.29,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23446,"numValue":null,"references":[],"strValue":"Yes","type":"REVERSIBILITY"}] | [{"id":20771,"numValue":9.0,"position":29,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:16679 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,679 | train | mutant | 1,206 | 341 | 1,352 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | H29E | H29E | 1 | 1 | 0 | 0 | 29 | H | E | 9 | CONSERVATION | 1C9O | 231 | null | 29 | A|B | E | true | true | 63.398842 | 9.869 | 6,562 | ProTherm | 7 | DSC | Thermal | Na cacodylate/HCl | 0.1 M | 75 | NaCl | 2 M | 1C9O_A:H29E | null | null | null | 0.48 | null | 0.96 | null | null | null | null | null | null | null | null | null | null | Yes | DCP|DDG|REVERSIBILITY | potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 223 | ARTICLE | The correlation between protein stability and dipole moment: a critical test. | 2,006 | 10.1093/protein/gzl019 | 16720692 | Protein Eng Des Sel;19;355-8 | 2 | Wunderlich Michael|Schmid Franz X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":75.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Na cacodylate/HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":... | [{"datasets":[],"id":23468,"numValue":0.96,"references":[],"strValue":null,"type":"DCP"},{"datasets":["potapov_with_uniprot_mapping.csv"],"id":23469,"numValue":0.48,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23470,"numValue":null,"references":[],"strValue":"Yes","type":"REVERSIBILITY"}] | [{"id":20771,"numValue":9.0,"position":29,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:16680 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,680 | train | mutant | 1,206 | 341 | 1,352 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | H29E | H29E | 1 | 1 | 0 | 0 | 29 | H | E | 9 | CONSERVATION | 1C9O | 231 | null | 29 | A|B | E | true | true | 63.398842 | 9.869 | 5,083,309 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159300,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159301,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":20771,"numValue":9.0,"position":29,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16681 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,681 | train | mutant | 4,901,480 | 341 | 4,908,066 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delH29 | delH29 | 1 | 0 | 1 | 0 | 29 | H | - | 9 | CONSERVATION | 1C9O | 231 | null | 29 | A|B | E | true | true | 63.398842 | 9.869 | 5,083,305 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.028456 | 0.354953 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159292,"numValue":-1.02845599028186,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159293,"numValue":0.354952560797601,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20771,"numValue":9.0,"position":29,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16682 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,682 | train | mutant | 4,901,481 | 341 | 4,908,067 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | H29A | H29A | 1 | 1 | 0 | 0 | 29 | H | A | 9 | CONSERVATION | 1C9O | 231 | null | 29 | A|B | E | true | true | 63.398842 | 9.869 | 5,083,306 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.532265 | 0.393313 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159294,"numValue":-0.532264702860048,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159295,"numValue":0.393312798485383,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20771,"numValue":9.0,"position":29,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16683 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,683 | train | mutant | 4,901,482 | 341 | 4,908,068 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | H29C | H29C | 1 | 1 | 0 | 0 | 29 | H | C | 9 | CONSERVATION | 1C9O | 231 | null | 29 | A|B | E | true | true | 63.398842 | 9.869 | 5,083,307 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.543576 | 0.938831 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159296,"numValue":-0.543576436500197,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159297,"numValue":0.938830975499815,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20771,"numValue":9.0,"position":29,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16686 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,686 | train | mutant | 4,901,485 | 341 | 4,908,071 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | H29G | H29G | 1 | 1 | 0 | 0 | 29 | H | G | 9 | CONSERVATION | 1C9O | 231 | null | 29 | A|B | E | true | true | 63.398842 | 9.869 | 5,083,311 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159304,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159305,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":20771,"numValue":9.0,"position":29,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16687 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,687 | train | mutant | 4,902,209 | 341 | 4,908,795 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | H29I | H29I | 1 | 1 | 0 | 0 | 29 | H | I | 9 | CONSERVATION | 1C9O | 231 | null | 29 | A|B | E | true | true | 63.398842 | 9.869 | 5,084,051 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.537872 | 0.160166 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160784,"numValue":-0.537872377384184,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160785,"numValue":0.160166295312078,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20771,"numValue":9.0,"position":29,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16688 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,688 | train | mutant | 4,902,210 | 341 | 4,908,796 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | H29K | H29K | 1 | 1 | 0 | 0 | 29 | H | K | 9 | CONSERVATION | 1C9O | 231 | null | 29 | A|B | E | true | true | 63.398842 | 9.869 | 5,084,052 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.196887 | 0.125587 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160786,"numValue":-0.196886572287133,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160787,"numValue":0.125586633578042,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20771,"numValue":9.0,"position":29,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16689 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,689 | train | mutant | 4,902,211 | 341 | 4,908,797 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | H29L | H29L | 1 | 1 | 0 | 0 | 29 | H | L | 9 | CONSERVATION | 1C9O | 231 | null | 29 | A|B | E | true | true | 63.398842 | 9.869 | 5,084,053 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.479655 | 0.118724 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160788,"numValue":-0.47965501690181,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160789,"numValue":0.118724477431574,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20771,"numValue":9.0,"position":29,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16690 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,690 | train | mutant | 4,902,212 | 341 | 4,908,798 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | H29M | H29M | 1 | 1 | 0 | 0 | 29 | H | M | 9 | CONSERVATION | 1C9O | 231 | null | 29 | A|B | E | true | true | 63.398842 | 9.869 | 5,084,054 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.274184 | 0.130836 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160790,"numValue":-0.274183932563163,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160791,"numValue":0.130835918654149,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20771,"numValue":9.0,"position":29,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16691 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,691 | train | mutant | 4,902,213 | 341 | 4,908,799 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | H29N | H29N | 1 | 1 | 0 | 0 | 29 | H | N | 9 | CONSERVATION | 1C9O | 231 | null | 29 | A|B | E | true | true | 63.398842 | 9.869 | 5,084,055 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.227519 | 0.124638 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160792,"numValue":-0.227519207923517,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160793,"numValue":0.124638140432507,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20771,"numValue":9.0,"position":29,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16692 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,692 | train | mutant | 4,902,214 | 341 | 4,908,800 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | H29P | H29P | 1 | 1 | 0 | 0 | 29 | H | P | 9 | CONSERVATION | 1C9O | 231 | null | 29 | A|B | E | true | true | 63.398842 | 9.869 | 5,084,056 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160794,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160795,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":20771,"numValue":9.0,"position":29,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16693 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,693 | train | mutant | 4,902,215 | 341 | 4,908,801 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | H29Q | H29Q | 1 | 1 | 0 | 0 | 29 | H | Q | 9 | CONSERVATION | 1C9O | 231 | null | 29 | A|B | E | true | true | 63.398842 | 9.869 | 5,084,057 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.173683 | 0.149076 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160796,"numValue":-0.17368254492513,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160797,"numValue":0.149075665317504,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20771,"numValue":9.0,"position":29,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16694 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,694 | train | mutant | 4,902,216 | 341 | 4,908,802 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | H29R | H29R | 1 | 1 | 0 | 0 | 29 | H | R | 9 | CONSERVATION | 1C9O | 231 | null | 29 | A|B | E | true | true | 63.398842 | 9.869 | 5,084,058 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.28132 | 0.108626 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160798,"numValue":-0.281319711880669,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160799,"numValue":0.108626264926065,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20771,"numValue":9.0,"position":29,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16695 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,695 | train | mutant | 4,902,217 | 341 | 4,908,803 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | H29S | H29S | 1 | 1 | 0 | 0 | 29 | H | S | 9 | CONSERVATION | 1C9O | 231 | null | 29 | A|B | E | true | true | 63.398842 | 9.869 | 5,084,059 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.344949 | 0.140794 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160800,"numValue":-0.344948954570467,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160801,"numValue":0.140793703670015,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20771,"numValue":9.0,"position":29,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16696 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,696 | train | mutant | 4,902,218 | 341 | 4,908,804 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | H29T | H29T | 1 | 1 | 0 | 0 | 29 | H | T | 9 | CONSERVATION | 1C9O | 231 | null | 29 | A|B | E | true | true | 63.398842 | 9.869 | 5,084,060 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.279581 | 0.120331 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160802,"numValue":-0.279581114045627,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160803,"numValue":0.120330709464856,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20771,"numValue":9.0,"position":29,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16697 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,697 | train | mutant | 4,902,219 | 341 | 4,908,805 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | H29V | H29V | 1 | 1 | 0 | 0 | 29 | H | V | 9 | CONSERVATION | 1C9O | 231 | null | 29 | A|B | E | true | true | 63.398842 | 9.869 | 5,084,061 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.505806 | 0.283868 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160804,"numValue":-0.50580559118452,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160805,"numValue":0.283867857299523,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20771,"numValue":9.0,"position":29,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16699 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,699 | train | mutant | 4,902,221 | 341 | 4,908,807 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | H29Y | H29Y | 1 | 1 | 0 | 0 | 29 | H | Y | 9 | CONSERVATION | 1C9O | 231 | null | 29 | A|B | E | true | true | 63.398842 | 9.869 | 5,084,063 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.149248 | 0.051618 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160808,"numValue":-0.149247924618856,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160809,"numValue":0.051617588565603,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20771,"numValue":9.0,"position":29,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16700 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,700 | train | mutant | 4,901,486 | 341 | 4,908,072 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delF30 | delF30 | 1 | 0 | 1 | 0 | 30 | F | - | 5 | CONSERVATION | 1C9O | 231 | null | 30 | A|B | G | true | true | 82.808983 | 11.409091 | 5,083,312 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.260364 | 0.164048 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159306,"numValue":-1.26036428340139,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159307,"numValue":0.164047642364343,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20772,"numValue":5.0,"position":30,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16701 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,701 | train | mutant | 4,901,487 | 341 | 4,908,073 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F30A | F30A | 1 | 1 | 0 | 0 | 30 | F | A | 5 | CONSERVATION | 1C9O | 231 | null | 30 | A|B | G | true | true | 82.808983 | 11.409091 | 5,083,313 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.034688 | 0.047116 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159308,"numValue":-0.0346877831950362,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159309,"numValue":0.0471155034018819,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20772,"numValue":5.0,"position":30,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16702 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,702 | train | mutant | 4,901,488 | 341 | 4,908,074 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F30C | F30C | 1 | 1 | 0 | 0 | 30 | F | C | 5 | CONSERVATION | 1C9O | 231 | null | 30 | A|B | G | true | true | 82.808983 | 11.409091 | 5,083,314 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.090735 | 0.051744 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159310,"numValue":-0.0907354826491708,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159311,"numValue":0.0517441155713616,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20772,"numValue":5.0,"position":30,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16703 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,703 | train | mutant | 4,901,489 | 341 | 4,908,075 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F30D | F30D | 1 | 1 | 0 | 0 | 30 | F | D | 5 | CONSERVATION | 1C9O | 231 | null | 30 | A|B | G | true | true | 82.808983 | 11.409091 | 5,083,315 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.18844 | 0.068311 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159312,"numValue":-0.188439583146539,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159313,"numValue":0.0683113643125909,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20772,"numValue":5.0,"position":30,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16705 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,705 | train | mutant | 4,902,194 | 341 | 4,908,780 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F30G | F30G | 1 | 1 | 0 | 0 | 30 | F | G | 5 | CONSERVATION | 1C9O | 231 | null | 30 | A|B | G | true | true | 82.808983 | 11.409091 | 5,084,036 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.088792 | 0.03958 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160754,"numValue":-0.0887923787612503,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160755,"numValue":0.0395799947751075,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20772,"numValue":5.0,"position":30,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16706 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,706 | train | mutant | 4,902,195 | 341 | 4,908,781 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F30H | F30H | 1 | 1 | 0 | 0 | 30 | F | H | 5 | CONSERVATION | 1C9O | 231 | null | 30 | A|B | G | true | true | 82.808983 | 11.409091 | 5,084,037 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.022652 | 0.067001 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160756,"numValue":-0.0226521574048175,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160757,"numValue":0.0670006879835547,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20772,"numValue":5.0,"position":30,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16707 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,707 | train | mutant | 4,902,196 | 341 | 4,908,782 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F30I | F30I | 1 | 1 | 0 | 0 | 30 | F | I | 5 | CONSERVATION | 1C9O | 231 | null | 30 | A|B | G | true | true | 82.808983 | 11.409091 | 5,084,038 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.087325 | 0.068227 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160758,"numValue":-0.087325270121042,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160759,"numValue":0.0682273686381192,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20772,"numValue":5.0,"position":30,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16708 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,708 | train | mutant | 4,902,197 | 341 | 4,908,783 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F30K | F30K | 1 | 1 | 0 | 0 | 30 | F | K | 5 | CONSERVATION | 1C9O | 231 | null | 30 | A|B | G | true | true | 82.808983 | 11.409091 | 5,084,039 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.01631 | 0.056765 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160760,"numValue":-0.0163095059097753,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160761,"numValue":0.0567653852900779,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20772,"numValue":5.0,"position":30,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16709 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,709 | train | mutant | 4,902,198 | 341 | 4,908,784 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F30L | F30L | 1 | 1 | 0 | 0 | 30 | F | L | 5 | CONSERVATION | 1C9O | 231 | null | 30 | A|B | G | true | true | 82.808983 | 11.409091 | 5,084,040 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.103287 | 0.026912 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160762,"numValue":-0.103286819355341,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160763,"numValue":0.0269115146307639,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20772,"numValue":5.0,"position":30,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16710 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,710 | train | mutant | 4,902,199 | 341 | 4,908,785 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F30M | F30M | 1 | 1 | 0 | 0 | 30 | F | M | 5 | CONSERVATION | 1C9O | 231 | null | 30 | A|B | G | true | true | 82.808983 | 11.409091 | 5,084,041 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.169282 | 0.04709 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160764,"numValue":-0.169282404546841,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160765,"numValue":0.047089907542858,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20772,"numValue":5.0,"position":30,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16711 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,711 | train | mutant | 4,902,200 | 341 | 4,908,786 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F30N | F30N | 1 | 1 | 0 | 0 | 30 | F | N | 5 | CONSERVATION | 1C9O | 231 | null | 30 | A|B | G | true | true | 82.808983 | 11.409091 | 5,084,042 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.0695 | 0.077335 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160766,"numValue":-0.069500048335302,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160767,"numValue":0.0773346455824819,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20772,"numValue":5.0,"position":30,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16712 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,712 | train | mutant | 4,902,201 | 341 | 4,908,787 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F30P | F30P | 1 | 1 | 0 | 0 | 30 | F | P | 5 | CONSERVATION | 1C9O | 231 | null | 30 | A|B | G | true | true | 82.808983 | 11.409091 | 5,084,043 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.227471 | 0.049731 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160768,"numValue":-0.22747060068776,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160769,"numValue":0.0497305726855761,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20772,"numValue":5.0,"position":30,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16713 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,713 | train | mutant | 4,902,202 | 341 | 4,908,788 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F30Q | F30Q | 1 | 1 | 0 | 0 | 30 | F | Q | 5 | CONSERVATION | 1C9O | 231 | null | 30 | A|B | G | true | true | 82.808983 | 11.409091 | 5,084,044 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.025132 | 0.073691 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160770,"numValue":-0.0251323119707294,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160771,"numValue":0.073691473985423,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20772,"numValue":5.0,"position":30,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16715 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,715 | train | mutant | 4,902,204 | 341 | 4,908,790 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F30S | F30S | 1 | 1 | 0 | 0 | 30 | F | S | 5 | CONSERVATION | 1C9O | 231 | null | 30 | A|B | G | true | true | 82.808983 | 11.409091 | 5,084,046 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.047236 | 0.035986 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160774,"numValue":-0.0472355632742003,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160775,"numValue":0.0359862187994581,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20772,"numValue":5.0,"position":30,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16716 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,716 | train | mutant | 4,902,205 | 341 | 4,908,791 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F30T | F30T | 1 | 1 | 0 | 0 | 30 | F | T | 5 | CONSERVATION | 1C9O | 231 | null | 30 | A|B | G | true | true | 82.808983 | 11.409091 | 5,084,047 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.126984 | 0.05043 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160776,"numValue":-0.126984032328921,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160777,"numValue":0.0504302382780194,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20772,"numValue":5.0,"position":30,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16717 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,717 | train | mutant | 4,902,206 | 341 | 4,908,792 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F30V | F30V | 1 | 1 | 0 | 0 | 30 | F | V | 5 | CONSERVATION | 1C9O | 231 | null | 30 | A|B | G | true | true | 82.808983 | 11.409091 | 5,084,048 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.048624 | 0.046673 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160778,"numValue":-0.0486238333490964,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160779,"numValue":0.0466725907130425,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20772,"numValue":5.0,"position":30,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16718 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,718 | train | mutant | 4,902,207 | 341 | 4,908,793 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F30W | F30W | 1 | 1 | 0 | 0 | 30 | F | W | 5 | CONSERVATION | 1C9O | 231 | null | 30 | A|B | G | true | true | 82.808983 | 11.409091 | 5,084,049 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.026331 | 0.050836 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160780,"numValue":-0.0263314880431098,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160781,"numValue":0.0508358538049832,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20772,"numValue":5.0,"position":30,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16719 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,719 | train | mutant | 4,902,208 | 341 | 4,908,794 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | F30Y | F30Y | 1 | 1 | 0 | 0 | 30 | F | Y | 5 | CONSERVATION | 1C9O | 231 | null | 30 | A|B | G | true | true | 82.808983 | 11.409091 | 5,084,050 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.011154 | 0.040641 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160782,"numValue":0.011154175063758,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160783,"numValue":0.040641452322082,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20772,"numValue":5.0,"position":30,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16720 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,720 | train | mutant | 317 | 341 | 352 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T31S | T31S | 1 | 1 | 0 | 0 | 31 | T | S | 7 | CONSERVATION | 1C9O | 231 | null | 31 | A|B | G | true | true | 28.842583 | 10.426429 | 562 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | null | 1C9O_A:T31S | 77.8 | 0.9 | null | null | null | null | 59.75 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | M47andM8_S2760.csv|AUTOMUTE_S1749.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:T31S... | [{"datasets":["M47andM8_S2760.csv"],"id":2232,"numValue":77.8,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","M47andM8_S2760.csv","Saraboji_S1791.csv"],"id":2233,"numValue":0.9,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":2234,"numValue":59.75,"references":[],"strVal... | [{"id":20773,"numValue":7.0,"position":31,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16721 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,721 | train | mutant | 317 | 341 | 352 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T31S | T31S | 1 | 1 | 0 | 0 | 31 | T | S | 7 | CONSERVATION | 1C9O | 231 | null | 31 | A|B | G | true | true | 28.842583 | 10.426429 | 4,180 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | null | 1C9O_A:T31S | 77.8 | 0.9 | null | null | null | null | 59.75 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | AUTOMUTE_S1749.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:T31S"... | [{"datasets":[],"id":15502,"numValue":77.8,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","Saraboji_S1791.csv"],"id":15503,"numValue":0.9,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":15504,"numValue":59.75,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[]... | [{"id":20773,"numValue":7.0,"position":31,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16722 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,722 | train | mutant | 317 | 341 | 352 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T31S | T31S | 1 | 1 | 0 | 0 | 31 | T | S | 7 | CONSERVATION | 1C9O | 231 | null | 31 | A|B | G | true | true | 28.842583 | 10.426429 | 6,618 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | 1C9O_A:T31S | null | null | 1.24 | -0.17 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":23619,"numValue":1.24,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":23620,"numValue":-0.17,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23621,"numValue":null,"referenc... | [{"id":20773,"numValue":7.0,"position":31,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16723 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,723 | train | mutant | 317 | 341 | 352 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T31S | T31S | 1 | 1 | 0 | 0 | 31 | T | S | 7 | CONSERVATION | 1C9O | 231 | null | 31 | A|B | G | true | true | 28.842583 | 10.426429 | 6,632 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | NaCl | 2 M | 1C9O_A:T31S | null | null | 2.39 | -0.19 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":23661,"numValue":2.39,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","potapov_with_uniprot_mapping.csv"],"id":23662,"numValue":-0.19,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23663,"numValue":null,"references":[],"strValue":"yes","type":"... | [{"id":20773,"numValue":7.0,"position":31,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:16724 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,724 | train | mutant | 317 | 341 | 352 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T31S | T31S | 1 | 1 | 0 | 0 | 31 | T | S | 7 | CONSERVATION | 1C9O | 231 | null | 31 | A|B | G | true | true | 28.842583 | 10.426429 | 6,652 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | 70 | 1C9O_A:T31S | null | null | 1.24 | -0.17 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","typ... | [{"datasets":[],"id":23717,"numValue":1.24,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":23718,"numValue":-0.17,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23719,"numValue":null,"referenc... | [{"id":20773,"numValue":7.0,"position":31,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:16725 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,725 | train | mutant | 317 | 341 | 352 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T31S | T31S | 1 | 1 | 0 | 0 | 31 | T | S | 7 | CONSERVATION | 1C9O | 231 | null | 31 | A|B | G | true | true | 28.842583 | 10.426429 | 6,662 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | 70 | NaCl | 2 M | 1C9O_A:T31S | null | null | 2.39 | -0.19 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","typ... | [{"datasets":[],"id":23747,"numValue":2.39,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","potapov_with_uniprot_mapping.csv"],"id":23748,"numValue":-0.19,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23749,"numValue":null,"references":[],"strValue":"yes","type":"... | [{"id":20773,"numValue":7.0,"position":31,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:16727 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,727 | train | mutant | 317 | 341 | 352 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T31S | T31S | 1 | 1 | 0 | 0 | 31 | T | S | 7 | CONSERVATION | 1C9O | 231 | null | 31 | A|B | G | true | true | 28.842583 | 10.426429 | 5,083,333 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.010671 | 0.031803 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159348,"numValue":-0.0106710665620329,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159349,"numValue":0.0318031097288208,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20773,"numValue":7.0,"position":31,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16728 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,728 | train | mutant | 4,901,491 | 341 | 4,908,077 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delT31 | delT31 | 1 | 0 | 1 | 0 | 31 | T | - | 7 | CONSERVATION | 1C9O | 231 | null | 31 | A|B | G | true | true | 28.842583 | 10.426429 | 5,083,317 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.187225 | 0.155832 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159316,"numValue":-1.18722473865027,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159317,"numValue":0.155832248918994,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20773,"numValue":7.0,"position":31,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16729 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,729 | train | mutant | 4,901,492 | 341 | 4,908,078 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T31A | T31A | 1 | 1 | 0 | 0 | 31 | T | A | 7 | CONSERVATION | 1C9O | 231 | null | 31 | A|B | G | true | true | 28.842583 | 10.426429 | 5,083,318 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.134285 | 0.049022 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159318,"numValue":-0.134284602031065,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159319,"numValue":0.0490221815015434,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20773,"numValue":7.0,"position":31,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:16730 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 16,730 | train | mutant | 4,901,493 | 341 | 4,908,079 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | T31C | T31C | 1 | 1 | 0 | 0 | 31 | T | C | 7 | CONSERVATION | 1C9O | 231 | null | 31 | A|B | G | true | true | 28.842583 | 10.426429 | 5,083,319 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.145543 | 0.049968 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159320,"numValue":-0.14554310482035,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159321,"numValue":0.0499682146467315,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20773,"numValue":7.0,"position":31,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.