row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:17175 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,175 | train | mutant | 4,901,964 | 341 | 4,908,550 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | I51Q | I51Q | 1 | 1 | 0 | 0 | 51 | I | Q | 5 | CONSERVATION | 1C9O | 231 | null | 51 | A|B | E | true | false | 71.652686 | 13.63125 | 5,083,801 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.006824 | 0.046864 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160284,"numValue":0.00682398168326416,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160285,"numValue":0.0468636112218535,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20793,"numValue":5.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17176 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,176 | train | mutant | 4,901,965 | 341 | 4,908,551 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | I51R | I51R | 1 | 1 | 0 | 0 | 51 | I | R | 5 | CONSERVATION | 1C9O | 231 | null | 51 | A|B | E | true | false | 71.652686 | 13.63125 | 5,083,802 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.004193 | 0.033546 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160286,"numValue":-0.00419326324074104,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160287,"numValue":0.0335456376367059,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20793,"numValue":5.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17178 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,178 | train | mutant | 4,901,967 | 341 | 4,908,553 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | I51T | I51T | 1 | 1 | 0 | 0 | 51 | I | T | 5 | CONSERVATION | 1C9O | 231 | null | 51 | A|B | E | true | false | 71.652686 | 13.63125 | 5,083,804 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.0333 | 0.047633 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160290,"numValue":-0.0333001058913077,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160291,"numValue":0.0476325836192314,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20793,"numValue":5.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17179 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,179 | train | mutant | 4,901,968 | 341 | 4,908,554 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | I51V | I51V | 1 | 1 | 0 | 0 | 51 | I | V | 5 | CONSERVATION | 1C9O | 231 | null | 51 | A|B | E | true | false | 71.652686 | 13.63125 | 5,083,805 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.009212 | 0.048905 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160292,"numValue":0.00921166394700538,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160293,"numValue":0.0489046527621114,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20793,"numValue":5.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17180 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,180 | train | mutant | 4,901,969 | 341 | 4,908,555 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | I51W | I51W | 1 | 1 | 0 | 0 | 51 | I | W | 5 | CONSERVATION | 1C9O | 231 | null | 51 | A|B | E | true | false | 71.652686 | 13.63125 | 5,083,806 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.041253 | 0.039309 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160294,"numValue":-0.0412533166491566,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160295,"numValue":0.039308908664667,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20793,"numValue":5.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17181 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,181 | train | mutant | 4,901,970 | 341 | 4,908,556 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | I51Y | I51Y | 1 | 1 | 0 | 0 | 51 | I | Y | 5 | CONSERVATION | 1C9O | 231 | null | 51 | A|B | E | true | false | 71.652686 | 13.63125 | 5,083,807 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.037345 | 0.089311 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160296,"numValue":0.0373451763401085,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160297,"numValue":0.0893108757016908,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20793,"numValue":5.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17183 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,183 | train | mutant | 4,901,669 | 341 | 4,908,255 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V52A | V52A | 1 | 1 | 0 | 0 | 52 | V | A | 3 | CONSERVATION | 1C9O | 231 | null | 52 | A|B | E | true | true | 2.553048 | 11.026429 | 5,083,498 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.028636 | 0.036509 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159678,"numValue":0.0286361823433644,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159679,"numValue":0.0365094104875473,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20794,"numValue":3.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17184 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,184 | train | mutant | 4,901,670 | 341 | 4,908,256 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V52C | V52C | 1 | 1 | 0 | 0 | 52 | V | C | 3 | CONSERVATION | 1C9O | 231 | null | 52 | A|B | E | true | true | 2.553048 | 11.026429 | 5,083,499 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.013893 | 0.076592 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159680,"numValue":-0.0138933706299815,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159681,"numValue":0.0765924960804451,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20794,"numValue":3.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17185 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,185 | train | mutant | 4,901,671 | 341 | 4,908,257 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V52D | V52D | 1 | 1 | 0 | 0 | 52 | V | D | 3 | CONSERVATION | 1C9O | 231 | null | 52 | A|B | E | true | true | 2.553048 | 11.026429 | 5,083,500 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.092436 | 0.072074 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159682,"numValue":-0.0924361431294771,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159683,"numValue":0.0720740978541872,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20794,"numValue":3.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17186 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,186 | train | mutant | 4,901,672 | 341 | 4,908,258 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V52E | V52E | 1 | 1 | 0 | 0 | 52 | V | E | 3 | CONSERVATION | 1C9O | 231 | null | 52 | A|B | E | true | true | 2.553048 | 11.026429 | 5,083,501 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.004374 | 0.036916 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159684,"numValue":-0.00437405844690823,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159685,"numValue":0.0369159388821094,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20794,"numValue":3.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17187 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,187 | train | mutant | 4,901,673 | 341 | 4,908,259 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V52F | V52F | 1 | 1 | 0 | 0 | 52 | V | F | 3 | CONSERVATION | 1C9O | 231 | null | 52 | A|B | E | true | true | 2.553048 | 11.026429 | 5,083,502 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.029405 | 0.064417 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159686,"numValue":-0.0294050065479504,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159687,"numValue":0.0644173912344524,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20794,"numValue":3.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17188 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,188 | train | mutant | 4,901,674 | 341 | 4,908,260 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V52G | V52G | 1 | 1 | 0 | 0 | 52 | V | G | 3 | CONSERVATION | 1C9O | 231 | null | 52 | A|B | E | true | true | 2.553048 | 11.026429 | 5,083,503 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.028683 | 0.034515 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159688,"numValue":-0.0286830112656176,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159689,"numValue":0.034515316423776,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20794,"numValue":3.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17189 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,189 | train | mutant | 4,901,675 | 341 | 4,908,261 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V52H | V52H | 1 | 1 | 0 | 0 | 52 | V | H | 3 | CONSERVATION | 1C9O | 231 | null | 52 | A|B | E | true | true | 2.553048 | 11.026429 | 5,083,504 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.03303 | 0.075148 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159690,"numValue":-0.0330298022388087,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159691,"numValue":0.0751482091301955,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20794,"numValue":3.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17190 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,190 | train | mutant | 4,901,676 | 341 | 4,908,262 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V52I | V52I | 1 | 1 | 0 | 0 | 52 | V | I | 3 | CONSERVATION | 1C9O | 231 | null | 52 | A|B | E | true | true | 2.553048 | 11.026429 | 5,083,505 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.018436 | 0.048119 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159692,"numValue":-0.0184363688597015,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159693,"numValue":0.0481186678322188,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20794,"numValue":3.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17193 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,193 | train | mutant | 4,901,679 | 341 | 4,908,265 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V52M | V52M | 1 | 1 | 0 | 0 | 52 | V | M | 3 | CONSERVATION | 1C9O | 231 | null | 52 | A|B | E | true | true | 2.553048 | 11.026429 | 5,083,508 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.03831 | 0.059372 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159698,"numValue":0.0383102078012233,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159699,"numValue":0.0593719008858214,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20794,"numValue":3.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17194 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,194 | train | mutant | 4,901,680 | 341 | 4,908,266 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V52N | V52N | 1 | 1 | 0 | 0 | 52 | V | N | 3 | CONSERVATION | 1C9O | 231 | null | 52 | A|B | E | true | true | 2.553048 | 11.026429 | 5,083,509 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.019928 | 0.092541 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159700,"numValue":-0.0199283738889559,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159701,"numValue":0.0925411821804042,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20794,"numValue":3.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17195 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,195 | train | mutant | 4,901,681 | 341 | 4,908,267 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V52P | V52P | 1 | 1 | 0 | 0 | 52 | V | P | 3 | CONSERVATION | 1C9O | 231 | null | 52 | A|B | E | true | true | 2.553048 | 11.026429 | 5,083,510 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.514052 | 0.048314 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159702,"numValue":-0.514051630899242,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159703,"numValue":0.0483144838597769,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20794,"numValue":3.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17196 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,196 | train | mutant | 4,901,682 | 341 | 4,908,268 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V52Q | V52Q | 1 | 1 | 0 | 0 | 52 | V | Q | 3 | CONSERVATION | 1C9O | 231 | null | 52 | A|B | E | true | true | 2.553048 | 11.026429 | 5,083,511 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.001451 | 0.053589 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159704,"numValue":-0.00145051104751116,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159705,"numValue":0.0535891158310176,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20794,"numValue":3.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17197 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,197 | train | mutant | 4,901,683 | 341 | 4,908,269 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V52R | V52R | 1 | 1 | 0 | 0 | 52 | V | R | 3 | CONSERVATION | 1C9O | 231 | null | 52 | A|B | E | true | true | 2.553048 | 11.026429 | 5,083,512 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.008583 | 0.032485 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159706,"numValue":0.00858332650917862,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159707,"numValue":0.0324848439934393,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20794,"numValue":3.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17198 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,198 | train | mutant | 4,901,684 | 341 | 4,908,270 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V52S | V52S | 1 | 1 | 0 | 0 | 52 | V | S | 3 | CONSERVATION | 1C9O | 231 | null | 52 | A|B | E | true | true | 2.553048 | 11.026429 | 5,083,513 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.01794 | 0.039271 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159708,"numValue":-0.0179396266211179,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159709,"numValue":0.0392714336714412,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20794,"numValue":3.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17199 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,199 | train | mutant | 4,901,685 | 341 | 4,908,271 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V52T | V52T | 1 | 1 | 0 | 0 | 52 | V | T | 3 | CONSERVATION | 1C9O | 231 | null | 52 | A|B | E | true | true | 2.553048 | 11.026429 | 5,083,514 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.012391 | 0.027107 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159710,"numValue":0.0123912884908751,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159711,"numValue":0.0271074255017089,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20794,"numValue":3.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17200 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,200 | train | mutant | 4,901,957 | 341 | 4,908,543 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V52W | V52W | 1 | 1 | 0 | 0 | 52 | V | W | 3 | CONSERVATION | 1C9O | 231 | null | 52 | A|B | E | true | true | 2.553048 | 11.026429 | 5,083,794 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.053389 | 0.048327 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160270,"numValue":-0.0533891207667268,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160271,"numValue":0.0483266534518511,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20794,"numValue":3.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17201 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,201 | train | mutant | 4,901,958 | 341 | 4,908,544 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V52Y | V52Y | 1 | 1 | 0 | 0 | 52 | V | Y | 3 | CONSERVATION | 1C9O | 231 | null | 52 | A|B | E | true | true | 2.553048 | 11.026429 | 5,083,795 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.042953 | 0.092159 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160272,"numValue":-0.042953384358295,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160273,"numValue":0.092159200439899,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20794,"numValue":3.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17202 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,202 | train | mutant | 319 | 341 | 354 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q53E | Q53E | 1 | 1 | 0 | 0 | 53 | Q | E | 3 | CONSERVATION | 1C9O | 231 | null | 53 | A|B | E | true | false | 97.489505 | 18.374444 | 564 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | null | 1C9O_A:Q53E | 76.1 | -0.8 | null | null | null | null | 58.8 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv|AUTOMUTE_S1749.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:Q53E... | [{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv"],"id":2240,"numValue":76.1,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","capriotti_S1615_map.csv","khan_protherm_data_mapped.csv","Saraboji_S1791.csv"],"id":2241,"numValue":-0.8,"references":[],"strValue":null,"typ... | [{"id":20795,"numValue":3.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:17203 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,203 | train | mutant | 319 | 341 | 354 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q53E | Q53E | 1 | 1 | 0 | 0 | 53 | Q | E | 3 | CONSERVATION | 1C9O | 231 | null | 53 | A|B | E | true | false | 97.489505 | 18.374444 | 4,182 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | null | 1C9O_A:Q53E | 76.1 | -0.8 | null | null | null | null | 58.8 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv|AUTOMUTE_S1749.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:Q53E"... | [{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv"],"id":15510,"numValue":76.1,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","capriotti_S1615_map.csv","khan_protherm_data_mapped.csv","Saraboji_S1791.csv"],"id":15511,"numValue":-0.8,"references":[],"strValue":null,"t... | [{"id":20795,"numValue":3.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:17204 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,204 | train | mutant | 319 | 341 | 354 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q53E | Q53E | 1 | 1 | 0 | 0 | 53 | Q | E | 3 | CONSERVATION | 1C9O | 231 | null | 53 | A|B | E | true | false | 97.489505 | 18.374444 | 6,620 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | 1C9O_A:Q53E | null | null | 0.98 | 0.1 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv"],"id":23625,"numValue":0.98,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":23626,"numValue":0.1,"references":[],"strValue":null,"type":"DD... | [{"id":20795,"numValue":3.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:17205 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,205 | train | mutant | 319 | 341 | 354 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q53E | Q53E | 1 | 1 | 0 | 0 | 53 | Q | E | 3 | CONSERVATION | 1C9O | 231 | null | 53 | A|B | E | true | false | 97.489505 | 18.374444 | 6,634 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | NaCl | 2 M | 1C9O_A:Q53E | null | null | 2.2 | 0 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv"],"id":23667,"numValue":2.2,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":23668,"numValue":0.0,"references":[],"strValue":null,"type":"DDG... | [{"id":20795,"numValue":3.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:17206 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,206 | train | mutant | 319 | 341 | 354 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q53E | Q53E | 1 | 1 | 0 | 0 | 53 | Q | E | 3 | CONSERVATION | 1C9O | 231 | null | 53 | A|B | E | true | false | 97.489505 | 18.374444 | 6,654 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | 70 | 1C9O_A:Q53E | null | null | 0.98 | 0.1 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","typ... | [{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv"],"id":23723,"numValue":0.98,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":23724,"numValue":0.1,"references":[],"strValue":null,"type":"DD... | [{"id":20795,"numValue":3.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:17207 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,207 | train | mutant | 319 | 341 | 354 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q53E | Q53E | 1 | 1 | 0 | 0 | 53 | Q | E | 3 | CONSERVATION | 1C9O | 231 | null | 53 | A|B | E | true | false | 97.489505 | 18.374444 | 6,664 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | 70 | NaCl | 2 M | 1C9O_A:Q53E | null | null | 2.2 | 0 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","typ... | [{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv"],"id":23753,"numValue":2.2,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":23754,"numValue":0.0,"references":[],"strValue":null,"type":"DDG... | [{"id":20795,"numValue":3.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:17208 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,208 | train | mutant | 319 | 341 | 354 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q53E | Q53E | 1 | 1 | 0 | 0 | 53 | Q | E | 3 | CONSERVATION | 1C9O | 231 | null | 53 | A|B | E | true | false | 97.489505 | 18.374444 | 8,806 | ProTherm | 7 | CD | GdnHCl | sodium cacodylate-HCl | 100 mM | 25 | 1C9O_A:Q53E | null | null | 1.22 | -0.02 | null | null | null | 2.68 | 1.82 | null | null | null | null | null | null | null | yes | DG|DDG|M|CM|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","typ... | [{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv"],"id":29784,"numValue":1.22,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":29785,"numValue":-0.02,"references":[],"strValue":null,"type":"... | [{"id":20795,"numValue":3.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:17209 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,209 | train | mutant | 319 | 341 | 354 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q53E | Q53E | 1 | 1 | 0 | 0 | 53 | Q | E | 3 | CONSERVATION | 1C9O | 231 | null | 53 | A|B | E | true | false | 97.489505 | 18.374444 | 5,083,519 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.003466 | 0.051678 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159720,"numValue":0.00346593301789832,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159721,"numValue":0.0516778852487877,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20795,"numValue":3.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17211 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,211 | train | mutant | 4,901,687 | 341 | 4,908,273 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q53A | Q53A | 1 | 1 | 0 | 0 | 53 | Q | A | 3 | CONSERVATION | 1C9O | 231 | null | 53 | A|B | E | true | false | 97.489505 | 18.374444 | 5,083,516 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.00212 | 0.045339 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159714,"numValue":-0.00212034246708107,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159715,"numValue":0.0453389682121023,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20795,"numValue":3.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17213 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,213 | train | mutant | 4,901,689 | 341 | 4,908,275 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q53D | Q53D | 1 | 1 | 0 | 0 | 53 | Q | D | 3 | CONSERVATION | 1C9O | 231 | null | 53 | A|B | E | true | false | 97.489505 | 18.374444 | 5,083,518 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.021817 | 0.092608 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159718,"numValue":0.0218169428294423,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159719,"numValue":0.0926082838765947,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20795,"numValue":3.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17216 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,216 | train | mutant | 4,901,692 | 341 | 4,908,278 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q53H | Q53H | 1 | 1 | 0 | 0 | 53 | Q | H | 3 | CONSERVATION | 1C9O | 231 | null | 53 | A|B | E | true | false | 97.489505 | 18.374444 | 5,083,522 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.045997 | 0.079677 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159726,"numValue":-0.0459966715335798,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159727,"numValue":0.0796767437434222,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20795,"numValue":3.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17218 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,218 | train | mutant | 4,901,694 | 341 | 4,908,280 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q53K | Q53K | 1 | 1 | 0 | 0 | 53 | Q | K | 3 | CONSERVATION | 1C9O | 231 | null | 53 | A|B | E | true | false | 97.489505 | 18.374444 | 5,083,524 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.032937 | 0.051506 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159730,"numValue":-0.0329367371654703,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159731,"numValue":0.0515062187186041,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20795,"numValue":3.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17219 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,219 | train | mutant | 4,901,695 | 341 | 4,908,281 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q53L | Q53L | 1 | 1 | 0 | 0 | 53 | Q | L | 3 | CONSERVATION | 1C9O | 231 | null | 53 | A|B | E | true | false | 97.489505 | 18.374444 | 5,083,525 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.026681 | 0.027911 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159732,"numValue":-0.0266812230320888,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159733,"numValue":0.0279114603136599,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20795,"numValue":3.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17220 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,220 | train | mutant | 4,901,696 | 341 | 4,908,282 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q53M | Q53M | 1 | 1 | 0 | 0 | 53 | Q | M | 3 | CONSERVATION | 1C9O | 231 | null | 53 | A|B | E | true | false | 97.489505 | 18.374444 | 5,083,526 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.009883 | 0.044209 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159734,"numValue":0.00988327368007845,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159735,"numValue":0.0442087314265324,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20795,"numValue":3.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17221 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,221 | train | mutant | 4,901,697 | 341 | 4,908,283 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q53N | Q53N | 1 | 1 | 0 | 0 | 53 | Q | N | 3 | CONSERVATION | 1C9O | 231 | null | 53 | A|B | E | true | false | 97.489505 | 18.374444 | 5,083,527 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.003729 | 0.071248 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159736,"numValue":0.00372853064521641,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159737,"numValue":0.0712479526776787,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20795,"numValue":3.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17222 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,222 | train | mutant | 4,901,698 | 341 | 4,908,284 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q53P | Q53P | 1 | 1 | 0 | 0 | 53 | Q | P | 3 | CONSERVATION | 1C9O | 231 | null | 53 | A|B | E | true | false | 97.489505 | 18.374444 | 5,083,528 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.09204 | 0.040553 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159738,"numValue":-0.0920401719894127,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159739,"numValue":0.040552607779458,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20795,"numValue":3.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17223 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,223 | train | mutant | 4,901,951 | 341 | 4,908,537 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q53R | Q53R | 1 | 1 | 0 | 0 | 53 | Q | R | 3 | CONSERVATION | 1C9O | 231 | null | 53 | A|B | E | true | false | 97.489505 | 18.374444 | 5,083,788 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.0016 | 0.043125 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160258,"numValue":-0.00160048215295472,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160259,"numValue":0.0431250568161902,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20795,"numValue":3.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17224 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,224 | train | mutant | 4,901,952 | 341 | 4,908,538 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q53S | Q53S | 1 | 1 | 0 | 0 | 53 | Q | S | 3 | CONSERVATION | 1C9O | 231 | null | 53 | A|B | E | true | false | 97.489505 | 18.374444 | 5,083,789 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.030228 | 0.035964 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160260,"numValue":-0.0302277729288026,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160261,"numValue":0.0359636342179664,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20795,"numValue":3.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17225 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,225 | train | mutant | 4,901,953 | 341 | 4,908,539 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q53T | Q53T | 1 | 1 | 0 | 0 | 53 | Q | T | 3 | CONSERVATION | 1C9O | 231 | null | 53 | A|B | E | true | false | 97.489505 | 18.374444 | 5,083,790 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.018271 | 0.043934 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160262,"numValue":0.0182709857038961,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160263,"numValue":0.0439337448818081,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20795,"numValue":3.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17226 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,226 | train | mutant | 4,901,954 | 341 | 4,908,540 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q53V | Q53V | 1 | 1 | 0 | 0 | 53 | Q | V | 3 | CONSERVATION | 1C9O | 231 | null | 53 | A|B | E | true | false | 97.489505 | 18.374444 | 5,083,791 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.000568 | 0.03951 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160264,"numValue":-0.000568467549882823,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160265,"numValue":0.0395104567894174,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20795,"numValue":3.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17227 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,227 | train | mutant | 4,901,955 | 341 | 4,908,541 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | Q53W | Q53W | 1 | 1 | 0 | 0 | 53 | Q | W | 3 | CONSERVATION | 1C9O | 231 | null | 53 | A|B | E | true | false | 97.489505 | 18.374444 | 5,083,792 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.006633 | 0.051644 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160266,"numValue":0.00663310936724507,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160267,"numValue":0.0516442632681523,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20795,"numValue":3.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17229 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,229 | train | mutant | 4,901,699 | 341 | 4,908,285 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delG54 | delG54 | 1 | 0 | 1 | 0 | 54 | G | - | 5 | CONSERVATION | 1C9O | 231 | null | 54 | A|B | E | true | false | 17.562469 | 14.13625 | 5,083,529 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.865844 | 0.139598 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159740,"numValue":-0.865844010047276,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159741,"numValue":0.139598380610225,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20796,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17230 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,230 | train | mutant | 4,901,700 | 341 | 4,908,286 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G54A | G54A | 1 | 1 | 0 | 0 | 54 | G | A | 5 | CONSERVATION | 1C9O | 231 | null | 54 | A|B | E | true | false | 17.562469 | 14.13625 | 5,083,530 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.028198 | 0.061271 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159742,"numValue":-0.0281975316792213,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159743,"numValue":0.0612712582615611,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20796,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17231 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,231 | train | mutant | 4,901,701 | 341 | 4,908,287 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G54C | G54C | 1 | 1 | 0 | 0 | 54 | G | C | 5 | CONSERVATION | 1C9O | 231 | null | 54 | A|B | E | true | false | 17.562469 | 14.13625 | 5,083,531 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.013005 | 0.046532 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159744,"numValue":-0.0130048066495078,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159745,"numValue":0.0465315823076556,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20796,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17232 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,232 | train | mutant | 4,901,702 | 341 | 4,908,288 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G54D | G54D | 1 | 1 | 0 | 0 | 54 | G | D | 5 | CONSERVATION | 1C9O | 231 | null | 54 | A|B | E | true | false | 17.562469 | 14.13625 | 5,083,532 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.069966 | 0.0673 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159746,"numValue":-0.0699659664731622,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159747,"numValue":0.0672999781461572,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20796,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17233 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,233 | train | mutant | 4,901,703 | 341 | 4,908,289 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G54E | G54E | 1 | 1 | 0 | 0 | 54 | G | E | 5 | CONSERVATION | 1C9O | 231 | null | 54 | A|B | E | true | false | 17.562469 | 14.13625 | 5,083,533 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.105994 | 0.059029 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159748,"numValue":-0.105994005278506,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159749,"numValue":0.0590294688376292,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20796,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17234 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,234 | train | mutant | 4,901,704 | 341 | 4,908,290 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G54F | G54F | 1 | 1 | 0 | 0 | 54 | G | F | 5 | CONSERVATION | 1C9O | 231 | null | 54 | A|B | E | true | false | 17.562469 | 14.13625 | 5,083,534 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.127032 | 0.074623 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159750,"numValue":-0.12703204679351,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159751,"numValue":0.0746231917069097,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20796,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17235 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,235 | train | mutant | 4,901,937 | 341 | 4,908,523 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G54H | G54H | 1 | 1 | 0 | 0 | 54 | G | H | 5 | CONSERVATION | 1C9O | 231 | null | 54 | A|B | E | true | false | 17.562469 | 14.13625 | 5,083,774 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.045103 | 0.113537 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160230,"numValue":0.045103365383764,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160231,"numValue":0.113537314773848,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20796,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17236 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,236 | train | mutant | 4,901,938 | 341 | 4,908,524 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G54I | G54I | 1 | 1 | 0 | 0 | 54 | G | I | 5 | CONSERVATION | 1C9O | 231 | null | 54 | A|B | E | true | false | 17.562469 | 14.13625 | 5,083,775 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.226922 | 0.128507 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160232,"numValue":-0.226922287357581,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160233,"numValue":0.128506920736016,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20796,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17237 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,237 | train | mutant | 4,901,939 | 341 | 4,908,525 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G54K | G54K | 1 | 1 | 0 | 0 | 54 | G | K | 5 | CONSERVATION | 1C9O | 231 | null | 54 | A|B | E | true | false | 17.562469 | 14.13625 | 5,083,776 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.037829 | 0.097934 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160234,"numValue":-0.0378288776130015,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160235,"numValue":0.0979335029392921,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20796,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17238 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,238 | train | mutant | 4,901,940 | 341 | 4,908,526 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G54L | G54L | 1 | 1 | 0 | 0 | 54 | G | L | 5 | CONSERVATION | 1C9O | 231 | null | 54 | A|B | E | true | false | 17.562469 | 14.13625 | 5,083,777 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.130864 | 0.051965 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160236,"numValue":-0.130864312393085,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160237,"numValue":0.0519647983494073,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20796,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17239 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,239 | train | mutant | 4,901,941 | 341 | 4,908,527 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G54M | G54M | 1 | 1 | 0 | 0 | 54 | G | M | 5 | CONSERVATION | 1C9O | 231 | null | 54 | A|B | E | true | false | 17.562469 | 14.13625 | 5,083,778 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.236233 | 0.177456 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160238,"numValue":-0.236232944089603,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160239,"numValue":0.177456481841797,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20796,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17240 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,240 | train | mutant | 4,901,942 | 341 | 4,908,528 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G54N | G54N | 1 | 1 | 0 | 0 | 54 | G | N | 5 | CONSERVATION | 1C9O | 231 | null | 54 | A|B | E | true | false | 17.562469 | 14.13625 | 5,083,779 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.11049 | 0.118366 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160240,"numValue":-0.110490174585973,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160241,"numValue":0.118365850875078,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20796,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17241 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,241 | train | mutant | 4,901,943 | 341 | 4,908,529 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G54P | G54P | 1 | 1 | 0 | 0 | 54 | G | P | 5 | CONSERVATION | 1C9O | 231 | null | 54 | A|B | E | true | false | 17.562469 | 14.13625 | 5,083,780 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.307732 | 0.062266 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160242,"numValue":-0.307732409573762,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160243,"numValue":0.0622655133412465,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20796,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17243 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,243 | train | mutant | 4,901,945 | 341 | 4,908,531 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G54R | G54R | 1 | 1 | 0 | 0 | 54 | G | R | 5 | CONSERVATION | 1C9O | 231 | null | 54 | A|B | E | true | false | 17.562469 | 14.13625 | 5,083,782 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.044121 | 0.036706 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160246,"numValue":-0.0441205507876164,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160247,"numValue":0.0367061571658388,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20796,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17244 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,244 | train | mutant | 4,901,946 | 341 | 4,908,532 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G54S | G54S | 1 | 1 | 0 | 0 | 54 | G | S | 5 | CONSERVATION | 1C9O | 231 | null | 54 | A|B | E | true | false | 17.562469 | 14.13625 | 5,083,783 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.025799 | 0.033961 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160248,"numValue":-0.0257991795344605,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160249,"numValue":0.0339612413578465,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20796,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17245 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,245 | train | mutant | 4,901,947 | 341 | 4,908,533 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G54T | G54T | 1 | 1 | 0 | 0 | 54 | G | T | 5 | CONSERVATION | 1C9O | 231 | null | 54 | A|B | E | true | false | 17.562469 | 14.13625 | 5,083,784 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.010145 | 0.068195 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160250,"numValue":0.0101452785362288,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160251,"numValue":0.0681954775492937,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20796,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17246 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,246 | train | mutant | 4,901,948 | 341 | 4,908,534 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G54V | G54V | 1 | 1 | 0 | 0 | 54 | G | V | 5 | CONSERVATION | 1C9O | 231 | null | 54 | A|B | E | true | false | 17.562469 | 14.13625 | 5,083,785 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.170663 | 0.067941 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160252,"numValue":-0.170662968596556,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160253,"numValue":0.0679407637785068,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20796,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17247 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,247 | train | mutant | 4,901,949 | 341 | 4,908,535 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | G54W | G54W | 1 | 1 | 0 | 0 | 54 | G | W | 5 | CONSERVATION | 1C9O | 231 | null | 54 | A|B | E | true | false | 17.562469 | 14.13625 | 5,083,786 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.179583 | 0.035991 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160254,"numValue":-0.179582989129023,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160255,"numValue":0.0359913284869242,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20796,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17249 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,249 | train | mutant | 1,209 | 341 | 1,355 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55K | N55K | 1 | 1 | 0 | 0 | 55 | N | K | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 2,372 | ProTherm | 7 | CD | Thermal | Na cacodylate/HCl | 0.1 M | null | 1C9O_A:N55K | 77.7 | 0.8 | null | null | null | 0.96 | 55.21 | null | null | null | null | null | null | null | null | null | Yes | TM|DTM|DCP|DHVH|REVERSIBILITY | potapov_with_uniprot_mapping.csv|Broom_S605.csv|EASE-MM_S1676.csv|PON-TStab_dataset.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 223 | ARTICLE | The correlation between protein stability and dipole moment: a critical test. | 2,006 | 10.1093/protein/gzl019 | 16720692 | Protein Eng Des Sel;19;355-8 | 2 | Wunderlich Michael|Schmid Franz X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Na cacodylate/HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:N55K","ty... | [{"datasets":["potapov_with_uniprot_mapping.csv"],"id":8688,"numValue":77.7,"references":[],"strValue":null,"type":"TM"},{"datasets":["potapov_with_uniprot_mapping.csv"],"id":8689,"numValue":0.8,"references":[],"strValue":null,"type":"DTM"},{"datasets":["potapov_with_uniprot_mapping.csv"],"id":8690,"numValue":0.96,"ref... | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:17250 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,250 | train | mutant | 1,209 | 341 | 1,355 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55K | N55K | 1 | 1 | 0 | 0 | 55 | N | K | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 6,549 | ProTherm | 7 | CD | Thermal | Na cacodylate/HCl | 0.1 M | 75 | 1C9O_A:N55K | null | null | null | -0.1 | null | 0.96 | null | null | null | null | null | null | null | null | null | null | Yes | DCP|DDG|REVERSIBILITY | potapov_with_uniprot_mapping.csv|khan_protherm_data_mapped.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 223 | ARTICLE | The correlation between protein stability and dipole moment: a critical test. | 2,006 | 10.1093/protein/gzl019 | 16720692 | Protein Eng Des Sel;19;355-8 | 2 | Wunderlich Michael|Schmid Franz X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":75.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Na cacodylate/HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":"... | [{"datasets":["potapov_with_uniprot_mapping.csv"],"id":23429,"numValue":0.96,"references":[],"strValue":null,"type":"DCP"},{"datasets":["khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":23430,"numValue":-0.1,"references":[],"strValue":null,"type":"DDG"},{"datasets":["potapov_with_uniprot_mapping.... | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:17251 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,251 | train | mutant | 1,209 | 341 | 1,355 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55K | N55K | 1 | 1 | 0 | 0 | 55 | N | K | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 6,557 | ProTherm | 7 | CD | Thermal | Na cacodylate/HCl | 0.1 M | 75 | NaCl | 0-2 M | 1C9O_A:N55K | null | null | null | 0.29 | null | 0.96 | null | null | null | null | null | null | null | null | null | null | Yes | DCP|DDG|REVERSIBILITY | potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 223 | ARTICLE | The correlation between protein stability and dipole moment: a critical test. | 2,006 | 10.1093/protein/gzl019 | 16720692 | Protein Eng Des Sel;19;355-8 | 2 | Wunderlich Michael|Schmid Franz X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":75.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Na cacodylate/HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":"... | [{"datasets":["potapov_with_uniprot_mapping.csv"],"id":23453,"numValue":0.96,"references":[],"strValue":null,"type":"DCP"},{"datasets":["potapov_with_uniprot_mapping.csv"],"id":23454,"numValue":0.29,"references":[],"strValue":null,"type":"DDG"},{"datasets":["potapov_with_uniprot_mapping.csv"],"id":23455,"numValue":null... | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:17252 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,252 | train | mutant | 1,209 | 341 | 1,355 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55K | N55K | 1 | 1 | 0 | 0 | 55 | N | K | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 6,565 | ProTherm | 7 | CD | Thermal | Na cacodylate/HCl | 0.1 M | 75 | NaCl | 2 M | 1C9O_A:N55K | null | null | null | -0.19 | null | 0.96 | null | null | null | null | null | null | null | null | null | null | Yes | DCP|DDG|REVERSIBILITY | potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 223 | ARTICLE | The correlation between protein stability and dipole moment: a critical test. | 2,006 | 10.1093/protein/gzl019 | 16720692 | Protein Eng Des Sel;19;355-8 | 2 | Wunderlich Michael|Schmid Franz X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":75.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Na cacodylate/HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":"... | [{"datasets":["potapov_with_uniprot_mapping.csv"],"id":23477,"numValue":0.96,"references":[],"strValue":null,"type":"DCP"},{"datasets":["potapov_with_uniprot_mapping.csv"],"id":23478,"numValue":-0.19,"references":[],"strValue":null,"type":"DDG"},{"datasets":["potapov_with_uniprot_mapping.csv"],"id":23479,"numValue":nul... | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:17253 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,253 | train | mutant | 1,209 | 341 | 1,355 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55K | N55K | 1 | 1 | 0 | 0 | 55 | N | K | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 5,083,544 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.018072 | 0.152735 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159770,"numValue":0.0180724073626962,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159771,"numValue":0.152734545350509,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17254 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,254 | train | mutant | 4,901,705 | 341 | 4,908,291 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delN55 | delN55 | 1 | 0 | 1 | 0 | 55 | N | - | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 5,083,535 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159752,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159753,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17255 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,255 | train | mutant | 4,901,706 | 341 | 4,908,292 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55A | N55A | 1 | 1 | 0 | 0 | 55 | N | A | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 5,083,536 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.035246 | 0.162025 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159754,"numValue":-0.0352455808638992,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159755,"numValue":0.162025047862826,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17256 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,256 | train | mutant | 4,901,707 | 341 | 4,908,293 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55C | N55C | 1 | 1 | 0 | 0 | 55 | N | C | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 5,083,537 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.089171 | 0.173317 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159756,"numValue":-0.0891711595374496,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159757,"numValue":0.173317220054439,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17257 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,257 | train | mutant | 4,901,708 | 341 | 4,908,294 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55D | N55D | 1 | 1 | 0 | 0 | 55 | N | D | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 5,083,538 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.308913 | 0.274838 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159758,"numValue":-0.308912616968774,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159759,"numValue":0.274838174101021,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17258 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,258 | train | mutant | 4,901,709 | 341 | 4,908,295 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55E | N55E | 1 | 1 | 0 | 0 | 55 | N | E | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 5,083,539 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.042697 | 0.311904 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159760,"numValue":-0.0426967144426545,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159761,"numValue":0.311904451606698,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17259 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,259 | train | mutant | 4,901,710 | 341 | 4,908,296 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55F | N55F | 1 | 1 | 0 | 0 | 55 | N | F | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 5,083,540 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.046265 | 0.432182 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159762,"numValue":0.0462651968725755,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159763,"numValue":0.432181693112221,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17260 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,260 | train | mutant | 4,901,711 | 341 | 4,908,297 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55G | N55G | 1 | 1 | 0 | 0 | 55 | N | G | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 5,083,541 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.064249 | 0.117512 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159764,"numValue":-0.0642486885601076,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159765,"numValue":0.117511608345218,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17262 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,262 | train | mutant | 4,901,713 | 341 | 4,908,299 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55I | N55I | 1 | 1 | 0 | 0 | 55 | N | I | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 5,083,543 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.058781 | 0.125896 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159768,"numValue":0.0587809673086804,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159769,"numValue":0.125896178681847,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17263 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,263 | train | mutant | 4,901,714 | 341 | 4,908,300 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55L | N55L | 1 | 1 | 0 | 0 | 55 | N | L | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 5,083,545 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.035268 | 0.107237 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159772,"numValue":-0.0352681061682741,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159773,"numValue":0.107237461357118,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17264 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,264 | train | mutant | 4,901,715 | 341 | 4,908,301 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55M | N55M | 1 | 1 | 0 | 0 | 55 | N | M | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 5,083,546 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.440034 | 1.000077 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159774,"numValue":-0.4400335992775,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159775,"numValue":1.00007727809521,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17265 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,265 | train | mutant | 4,901,929 | 341 | 4,908,515 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55P | N55P | 1 | 1 | 0 | 0 | 55 | N | P | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 5,083,766 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.026347 | 0.152607 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160214,"numValue":-0.0263474928646393,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160215,"numValue":0.15260692171809,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17266 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,266 | train | mutant | 4,901,930 | 341 | 4,908,516 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55Q | N55Q | 1 | 1 | 0 | 0 | 55 | N | Q | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 5,083,767 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.041738 | 0.179053 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160216,"numValue":-0.041738203464385,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160217,"numValue":0.179053407367745,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17267 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,267 | train | mutant | 4,901,931 | 341 | 4,908,517 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55R | N55R | 1 | 1 | 0 | 0 | 55 | N | R | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 5,083,768 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.074687 | 0.094306 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160218,"numValue":-0.0746867960532105,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160219,"numValue":0.0943056248383615,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17268 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,268 | train | mutant | 4,901,932 | 341 | 4,908,518 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55S | N55S | 1 | 1 | 0 | 0 | 55 | N | S | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 5,083,769 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.048983 | 0.092231 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160220,"numValue":0.0489830526767594,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160221,"numValue":0.0922308071969646,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17269 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,269 | train | mutant | 4,901,933 | 341 | 4,908,519 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55T | N55T | 1 | 1 | 0 | 0 | 55 | N | T | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 5,083,770 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.256448 | 0.177666 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160222,"numValue":-0.256448219223755,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160223,"numValue":0.177666085726717,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17270 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,270 | train | mutant | 4,901,934 | 341 | 4,908,520 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55V | N55V | 1 | 1 | 0 | 0 | 55 | N | V | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 5,083,771 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.005184 | 0.099215 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160224,"numValue":0.00518378386206963,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160225,"numValue":0.0992147185412907,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17271 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,271 | train | mutant | 4,901,935 | 341 | 4,908,521 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55W | N55W | 1 | 1 | 0 | 0 | 55 | N | W | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 5,083,772 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.002197 | 0.21576 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160226,"numValue":0.00219680994772212,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160227,"numValue":0.215760169160175,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17272 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,272 | train | mutant | 4,901,936 | 341 | 4,908,522 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N55Y | N55Y | 1 | 1 | 0 | 0 | 55 | N | Y | 2 | CONSERVATION | 1C9O | 231 | null | 55 | A|B | T | true | false | 146.515544 | 23.509375 | 5,083,773 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.164724 | 0.602412 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160228,"numValue":-0.164723994266759,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160229,"numValue":0.602411998033428,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20797,"numValue":2.0,"position":55,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17274 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,274 | train | mutant | 1,205 | 341 | 1,351 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R56E | R56E | 1 | 1 | 0 | 0 | 56 | R | E | 7 | CONSERVATION | 1C9O | 231 | null | 56 | A|B | T | true | false | 218.449071 | 20.133636 | 6,545 | ProTherm | 7 | CD | Thermal | Na cacodylate/HCl | 0.1 M | 75 | 1C9O_A:R56E | null | null | null | -0.76 | null | 0.96 | null | null | null | null | null | null | null | null | null | null | Yes | DCP|DDG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 223 | ARTICLE | The correlation between protein stability and dipole moment: a critical test. | 2,006 | 10.1093/protein/gzl019 | 16720692 | Protein Eng Des Sel;19;355-8 | 2 | Wunderlich Michael|Schmid Franz X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":75.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Na cacodylate/HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":"... | [{"datasets":[],"id":23417,"numValue":0.96,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":23418,"numValue":-0.76,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23419,"numValue":null,"references":[],"strValue":"Yes","type":"REVERSIBILITY"}] | [{"id":20798,"numValue":7.0,"position":56,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:17275 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,275 | train | mutant | 1,205 | 341 | 1,351 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R56E | R56E | 1 | 1 | 0 | 0 | 56 | R | E | 7 | CONSERVATION | 1C9O | 231 | null | 56 | A|B | T | true | false | 218.449071 | 20.133636 | 6,553 | ProTherm | 7 | CD | Thermal | Na cacodylate/HCl | 0.1 M | 75 | NaCl | 0-2 M | 1C9O_A:R56E | null | null | null | -0.53 | null | 0.96 | null | null | null | null | null | null | null | null | null | null | Yes | DCP|DDG|REVERSIBILITY | potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 223 | ARTICLE | The correlation between protein stability and dipole moment: a critical test. | 2,006 | 10.1093/protein/gzl019 | 16720692 | Protein Eng Des Sel;19;355-8 | 2 | Wunderlich Michael|Schmid Franz X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":75.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Na cacodylate/HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":"... | [{"datasets":[],"id":23441,"numValue":0.96,"references":[],"strValue":null,"type":"DCP"},{"datasets":["potapov_with_uniprot_mapping.csv"],"id":23442,"numValue":-0.53,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23443,"numValue":null,"references":[],"strValue":"Yes","type":"REVERSIBILITY"}] | [{"id":20798,"numValue":7.0,"position":56,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:17276 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,276 | train | mutant | 1,205 | 341 | 1,351 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R56E | R56E | 1 | 1 | 0 | 0 | 56 | R | E | 7 | CONSERVATION | 1C9O | 231 | null | 56 | A|B | T | true | false | 218.449071 | 20.133636 | 6,561 | ProTherm | 7 | CD | Thermal | Na cacodylate/HCl | 0.1 M | 75 | NaCl | 2 M | 1C9O_A:R56E | null | null | null | -0.24 | null | 0.96 | null | null | null | null | null | null | null | null | null | null | Yes | DCP|DDG|REVERSIBILITY | khan_protherm_data_mapped.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 223 | ARTICLE | The correlation between protein stability and dipole moment: a critical test. | 2,006 | 10.1093/protein/gzl019 | 16720692 | Protein Eng Des Sel;19;355-8 | 2 | Wunderlich Michael|Schmid Franz X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":75.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Na cacodylate/HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":"... | [{"datasets":[],"id":23465,"numValue":0.96,"references":[],"strValue":null,"type":"DCP"},{"datasets":["khan_protherm_data_mapped.csv"],"id":23466,"numValue":-0.24,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23467,"numValue":null,"references":[],"strValue":"Yes","type":"REVERSIBILITY"}] | [{"id":20798,"numValue":7.0,"position":56,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:17277 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,277 | train | mutant | 1,205 | 341 | 1,351 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R56E | R56E | 1 | 1 | 0 | 0 | 56 | R | E | 7 | CONSERVATION | 1C9O | 231 | null | 56 | A|B | T | true | false | 218.449071 | 20.133636 | 5,083,551 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.065843 | 0.053405 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159784,"numValue":-0.0658432430013846,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159785,"numValue":0.0534049359014826,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20798,"numValue":7.0,"position":56,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17278 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,278 | train | mutant | 4,901,716 | 341 | 4,908,302 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delR56 | delR56 | 1 | 0 | 1 | 0 | 56 | R | - | 7 | CONSERVATION | 1C9O | 231 | null | 56 | A|B | T | true | false | 218.449071 | 20.133636 | 5,083,547 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.076302 | 0.16896 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159776,"numValue":-1.07630159926119,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159777,"numValue":0.168959522091761,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20798,"numValue":7.0,"position":56,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17279 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,279 | train | mutant | 4,901,717 | 341 | 4,908,303 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R56A | R56A | 1 | 1 | 0 | 0 | 56 | R | A | 7 | CONSERVATION | 1C9O | 231 | null | 56 | A|B | T | true | false | 218.449071 | 20.133636 | 5,083,548 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.069358 | 0.049071 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159778,"numValue":-0.0693583760262072,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159779,"numValue":0.0490706464722195,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20798,"numValue":7.0,"position":56,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17280 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,280 | train | mutant | 4,901,718 | 341 | 4,908,304 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R56C | R56C | 1 | 1 | 0 | 0 | 56 | R | C | 7 | CONSERVATION | 1C9O | 231 | null | 56 | A|B | T | true | false | 218.449071 | 20.133636 | 5,083,549 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.096988 | 0.056515 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159780,"numValue":-0.0969880329267135,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159781,"numValue":0.056515342556093,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20798,"numValue":7.0,"position":56,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17281 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,281 | train | mutant | 4,901,719 | 341 | 4,908,305 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R56D | R56D | 1 | 1 | 0 | 0 | 56 | R | D | 7 | CONSERVATION | 1C9O | 231 | null | 56 | A|B | T | true | false | 218.449071 | 20.133636 | 5,083,550 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.17521 | 0.078877 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159782,"numValue":-0.175209523453283,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159783,"numValue":0.078876739775412,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20798,"numValue":7.0,"position":56,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17282 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,282 | train | mutant | 4,901,720 | 341 | 4,908,306 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R56F | R56F | 1 | 1 | 0 | 0 | 56 | R | F | 7 | CONSERVATION | 1C9O | 231 | null | 56 | A|B | T | true | false | 218.449071 | 20.133636 | 5,083,552 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.180984 | 0.049735 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159786,"numValue":-0.18098430016961,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159787,"numValue":0.0497353267103416,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20798,"numValue":7.0,"position":56,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17283 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,283 | train | mutant | 4,901,721 | 341 | 4,908,307 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R56G | R56G | 1 | 1 | 0 | 0 | 56 | R | G | 7 | CONSERVATION | 1C9O | 231 | null | 56 | A|B | T | true | false | 218.449071 | 20.133636 | 5,083,553 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.080888 | 0.039241 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159788,"numValue":-0.0808877752391579,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159789,"numValue":0.0392409178117248,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20798,"numValue":7.0,"position":56,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17284 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,284 | train | mutant | 4,901,722 | 341 | 4,908,308 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R56H | R56H | 1 | 1 | 0 | 0 | 56 | R | H | 7 | CONSERVATION | 1C9O | 231 | null | 56 | A|B | T | true | false | 218.449071 | 20.133636 | 5,083,554 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.068767 | 0.059116 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159790,"numValue":-0.0687673831719494,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159791,"numValue":0.0591161201269325,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20798,"numValue":7.0,"position":56,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17285 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,285 | train | mutant | 4,901,723 | 341 | 4,908,309 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R56I | R56I | 1 | 1 | 0 | 0 | 56 | R | I | 7 | CONSERVATION | 1C9O | 231 | null | 56 | A|B | T | true | false | 218.449071 | 20.133636 | 5,083,555 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.142912 | 0.092581 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159792,"numValue":-0.142912386377826,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159793,"numValue":0.0925807200172939,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20798,"numValue":7.0,"position":56,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17286 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,286 | train | mutant | 4,901,724 | 341 | 4,908,310 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R56K | R56K | 1 | 1 | 0 | 0 | 56 | R | K | 7 | CONSERVATION | 1C9O | 231 | null | 56 | A|B | T | true | false | 218.449071 | 20.133636 | 5,083,556 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.003314 | 0.057263 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159794,"numValue":0.00331359082778365,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159795,"numValue":0.0572628981311797,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20798,"numValue":7.0,"position":56,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17288 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,288 | train | mutant | 4,901,726 | 341 | 4,908,312 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R56M | R56M | 1 | 1 | 0 | 0 | 56 | R | M | 7 | CONSERVATION | 1C9O | 231 | null | 56 | A|B | T | true | false | 218.449071 | 20.133636 | 5,083,558 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.067702 | 0.063662 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159798,"numValue":-0.0677015806123153,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159799,"numValue":0.0636620229353746,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20798,"numValue":7.0,"position":56,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17289 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,289 | train | mutant | 4,901,727 | 341 | 4,908,313 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | R56N | R56N | 1 | 1 | 0 | 0 | 56 | R | N | 7 | CONSERVATION | 1C9O | 231 | null | 56 | A|B | T | true | false | 218.449071 | 20.133636 | 5,083,559 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.017954 | 0.102846 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159800,"numValue":0.0179544459003118,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159801,"numValue":0.102846153269228,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20798,"numValue":7.0,"position":56,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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